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Results for MligTC455_36727

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_36727 2161 45.01 Mlig455_013407, Mlig455_013448

Neo: -

Age: logFC(26M/2M)=-0.438

Region-enriched R3: 1.447/0.00030

Mlig455_013407 {REF} {Length: 3635} {RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611} {RNA1310_1688.1, RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611} {RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611, RNA815_14547}

Mlig455_013448 {REF} {Length: 3532} {RNA1509_17696} {RNA1310_1688.1} {RNA815_14547}

Cumulative graph for MligTC455_36727

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.662 5.742 0.35824 1.00000
RegionR2 -1.232 5.742 0.00733 0.08268
RegionR3 1.447 5.742 0.00000 0.00030
RegionR4 0.994 5.742 0.00681 0.04604
RegionR5 0.914 5.742 0.00198 0.01729
RegionR6 0.849 5.742 0.01068 0.17539
RegionR7 -2.043 5.742 0.00019 0.00963
RegionR8 -1.591 5.742 0.02161 0.28673

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.52 5.742 0.16350 0.90541
RegenerationR2 -0.111 5.742 0.79753 0.98883
RegenerationR3 -0.307 5.742 0.40947 0.80801
RegenerationR4 -0.041 5.742 0.91477 1.00000
RegenerationR5 -0.103 5.742 0.77430 0.98015
RegenerationR6 0.054 5.742 0.88547 1.00000
RegenerationBL 0.433 5.742 0.39578 0.76460
RegenerationTP 0.873 5.742 0.15006 0.57391


Genes with expression patterns similar to MligTC455_36727

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_36727 2161 45.01 Mlig455_013407, Mlig455_013448

Neo: -

Age: logFC(26M/2M)=-0.438

Region-enriched R3: 1.447/0.00030

6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_013407 {REF} {Length: 3635} {RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611} {RNA1310_1688.1, RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611} {RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611, RNA815_14547}

Mlig455_013448 {REF} {Length: 3532} {RNA1509_17696} {RNA1310_1688.1} {RNA815_14547}
2. MligTC455_37466 1949 40.61 Mlig455_031186

Neo: -

Age: Down-Down-Up

Region-enriched R3: 1.619/0.00008

ARHGEF10 5.124 0.830 0.858 0.892 0.726 0.978 0.840 Mlig455_031186 {REF} {Length: 5352} {Pfam: RhoGEF domain [PF00621.22, score=105.9]; WD40 repeated domain [PF19056.2, score=87.7]; PH domain [PF19057.2, score=32.3]} {Human: ENSG00000274726, ARHGEF10, Rho guanine nucleotide exchange factor 10, [RH, Score=289, Expect=7e-80]; ENSG00000104728, ARHGEF10, Rho guanine nucleotide exchange factor 10, [RH, Score=289, Expect=7e-80]} {Mouse: ENSMUSG00000071176, Arhgef10, Rho guanine nucleotide exchange factor (GEF) 10, [RH, Score=301, Expect=5e-84]} {Dmel: FBgn0263706, CG43658, [RH, Score=249, Expect=8e-67]} {Celegans: WBGene00019832, osg-1, Rho guanine nucleotide exchange factor osg-1, [Score=115, Expect=1e-25]} {Smed: dd_Smed_v6_2922_0_1, dd_Smed_v6_2922_0_1, [Score=112, Expect=7e-25]} {RNA1509_2853} {RNA1310_2593.1} {RNA815_1265}
3. MligTC455_31825 3098 64.55 Mlig455_047151

Neo: -

Age: -

Region-enriched R3: 1.610/0.00965
Region-enriched R4: 1.361/0.04740
Region-enriched R5: 1.152/0.04924

5.028 0.726 0.848 0.803 0.952 0.803 0.896 Mlig455_047151 {REF} {Length: 1650} {Pfam: VDE lipocalin domain [PF07137.13, score=61.0]} {RNA1509_31696, RNA1509_3758, RNA1509_5185} {RNA1310_14334.2, RNA1509_31696, RNA1509_3758, RNA1509_5185} {RNA1509_31696, RNA1509_3758, RNA1509_5185, RNA815_7820}
4. MligTC455_53810 10368 216.01 Mlig455_015254

Neo: -

Age: logFC(26M/2M)=-0.519

Region-enriched R3: 1.584/0.00569
Region-enriched R5: 1.232/0.02515

SULT1C4 4.945 0.773 0.821 0.730 0.961 0.885 0.775 Mlig455_015254 {REF} {Length: 3712} {Pfam: Sulfotransferase domain [PF00685.29, score=172.2]; Sulfotransferase family [PF13469.8, score=31.5]} {Human: ENSG00000198075, SULT1C4, sulfotransferase family 1C member 4, [Score=168, Expect=6e-50]; ENSG00000198203, SULT1C2, sulfotransferase family 1C member 2, [Score=167, Expect=7e-50]} {Mouse: ENSMUSG00000023122, Sult1c2, sulfotransferase family, cytosolic, 1C, member 2, [Score=163, Expect=3e-48]} {Dmel: FBgn0034887, St1, Sulfotransferase 1, [Score=111, Expect=2e-28]} {Celegans: WBGene00013748, ssu-1, Suppressor of Stomatin mutant Uncoordination, [Score=99.0, Expect=2e-23]} {Smed: dd_Smed_v6_4622_0_1, dd_Smed_v6_4622_0_1, [Score=152, Expect=1e-44]} {RNA1509_178, RNA1509_182} {RNA1310_14124, RNA1509_178, RNA1509_182} {RNA1509_178, RNA1509_182, RNA815_6793}
5. MligTC455_49488 5075 105.73 Mlig455_055474

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.341

Region-enriched R3: 1.609/0.02116

4.807 0.743 0.848 0.783 0.955 0.747 0.731 Mlig455_055474 {REF} {Length: 988} {Pfam: Universal stress protein family [PF00582.28, score=100.4]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=126, Expect=2e-37]} {RNA1509_12747, RNA1509_15238} {RNA1310_22621, RNA1509_15238} {RNA1509_15238, RNA815_17247}
6. MligTC455_49487 5068 105.57 Mlig455_036283

Neo: -

Age: logFC(26M/2M)=-0.424

Region-enriched R3: 1.606/0.02613

4.797 0.743 0.848 0.782 0.954 0.737 0.733 Mlig455_036283 {REF} {Length: 978} {Pfam: Universal stress protein family [PF00582.28, score=89.7]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=109, Expect=3e-31]} {RNA1509_12747} {RNA1310_22621} {RNA815_17247}
7. MligTC455_14822 1135 23.64 Mlig455_018937, Mlig455_018944

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.579

Region-enriched R4: 1.878/0.00075
Region-enriched R3: 1.574/0.00063
Region-enriched R5: 1.391/0.00033

Regeneration-downregulated R3: -1.760

Regeneration-depleted R3: -1.760

PANK1 4.671 0.913 0.919 0.952 0.987 0.900 -

Mlig455_018937 {REF} {Length: 2205} {Pfam: Fumble [PF03630.16, score=44.5]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [Score=64.7, Expect=3e-12]} {RNA1509_12016} {RNA1310_16423} {RNA815_7574.1}

Mlig455_018944 {REF} {Length: 2211} {Pfam: Fumble [PF03630.16, score=101.1]} {Human: ENSG00000152782, PANK1, pantothenate kinase 1, [Score=55.5, Expect=6e-08]} {Mouse: ENSMUSG00000029056, Pank4, pantothenate kinase 4, [Score=80.1, Expect=8e-16]} {Dmel: FBgn0011205, fbl, fumble, [Score=56.2, Expect=2e-08]} {Celegans: WBGene00004068, pnk-1, PaNtothenate Kinase, [Score=75.1, Expect=1e-14]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [Score=181, Expect=7e-54]} {RNA1509_12016} {RNA1310_16423, RNA1509_12016} {RNA1509_12016, RNA815_7574.1}
8. MligTC455_24085 1786 37.2 Mlig455_007320

Neo: -

Age: logFC(26M/2M)=0.210

Region-enriched R3: 2.481/0.00000
Region-enriched R5: 1.136/0.04856

ACHE 4.441 0.826 0.944 - 0.979 0.836 0.856 Mlig455_007320 {REF} {Length: 2268} {Pfam: Carboxylesterase family [PF00135.30, score=353.8]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=232, Expect=2e-67]} {Mouse: ENSMUSG00000023328, Ache, acetylcholinesterase, [Score=227, Expect=1e-65]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=202, Expect=2e-56]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=223, Expect=2e-64]} {Smed: dd_Smed_v6_14790_0_1, dd_Smed_v6_14790_0_1, [Score=206, Expect=5e-58]} {RNA1509_28908, RNA1509_31228, RNA1509_46106} {RNA1310_10437.1, RNA1509_28908, RNA1509_31228, RNA1509_46106} {RNA1509_28908, RNA1509_31228, RNA1509_46106, RNA815_3976}
9. MligTC455_41503 3372 70.25 Mlig455_015421

Neo: -

Age: -

Region-enriched R3: 1.663/0.00123

4.44 0.802 0.833 0.892 0.941 0.972 - Mlig455_015421 {REF} {Length: 3377} {Pfam: Fasciclin domain [PF02469.24, score=41.0]} {Dmel: FBgn0032638, SPH93, Serine protease homolog 93, [Score=61.6, Expect=2e-09]} {RNA1509_26815, RNA1509_27548, RNA1509_56488} {RNA1310_8987, RNA1509_26815, RNA1509_27548, RNA1509_56488} {RNA1509_26815, RNA1509_27548, RNA1509_56488, RNA815_3084.1}
10. MligTC455_48071 1712 35.67 Mlig455_048082

Neo: -

Age: logFC(26M/2M)=-0.321

Region-enriched R4: 1.489/0.04451

HSD11B1 4.421 0.812 0.900 0.793 0.959 0.957 - Mlig455_048082 {REF} {Length: 1293} {Pfam: short chain dehydrogenase [PF00106.27, score=123.3]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=75.2]; KR domain [PF08659.12, score=26.1]} {Human: ENSG00000117594, HSD11B1, hydroxysteroid 11-beta dehydrogenase 1, [Score=155, Expect=4e-45]} {Mouse: ENSMUSG00000016194, Hsd11b1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=150, Expect=1e-43]} {Dmel: FBgn0027583, CG7601, [Score=82.4, Expect=9e-18]} {Celegans: WBGene00000982, dhs-19, DeHydrogenases, Short chain, [Score=73.2, Expect=1e-14]} {Smed: dd_Smed_v6_4976_0_1, dd_Smed_v6_4976_0_1, [Score=62.8, Expect=3e-11]} {RNA1509_14549, RNA1509_28912} {RNA1310_26648, RNA1509_14549, RNA1509_28912} {RNA1509_14549, RNA1509_28912, RNA815_11342}
11. MligTC455_37113 9210 191.88 Mlig455_020693

Neo: -

Age: -

Region-enriched R3: 1.525/0.00009

LGMN 4.414 0.715 0.872 0.962 0.963 0.902 - Mlig455_020693 {REF} {Length: 3890} {Pfam: Peptidase C13 family [PF01650.20, score=361.0]} {Human: ENSG00000100600, LGMN, legumain, [RH, Score=382, Expect=2e-129]} {Mouse: ENSMUSG00000021190, Lgmn, legumain, [RH, Score=388, Expect=4e-132]} {Dmel: FBgn0023545, PIG-K, Phosphatidylinositol glycan anchor biosynthesis class K, [Score=127, Expect=1e-32]} {Celegans: WBGene00012144, T28H10.3, [RH, Score=327, Expect=7e-108]} {Smed: dd_Smed_v6_6456_0_1, dd_Smed_v6_6456_0_1, [Score=105, Expect=3e-25]} {RNA1509_312} {RNA1310_13933, RNA1509_312} {RNA1509_312, RNA815_6243.1}
12. MligTC455_20725 2475 51.57 Mlig455_035227

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.822

Region-enriched R3: 2.240/0.00003

SLC1A6 4.404 0.768 0.856 - 0.954 0.904 0.922 Mlig455_035227 {REF} {Length: 2154} {Pfam: Sodium:dicarboxylate symporter family [PF00375.20, score=422.3]} {Human: ENSG00000105143, SLC1A6, solute carrier family 1 member 6, [RH, Score=462, Expect=2e-157]} {Mouse: ENSMUSG00000024935, Slc1a1, solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1, [RH, Score=456, Expect=3e-156]; ENSMUSG00000005357, Slc1a6, solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6, [RH, Score=452, Expect=1e-153]} {Dmel: FBgn0026439, Eaat1, Excitatory amino acid transporter 1, [RH, Score=373, Expect=3e-124]} {Celegans: WBGene00001620, glt-1, Excitatory amino acid transporter, [Score=422, Expect=3e-143]} {Smed: dd_Smed_v6_1106_0_1, dd_Smed_v6_1106_0_1, [Score=422, Expect=8e-144]} {RNA1509_7401} {RNA1310_8553.1, RNA1509_7401} {RNA1509_7401, RNA815_2974.1}
13. MligTC455_45590 6933 144.44 Mlig455_060243

Neo: -

Age: Up-Down-Down

Region-enriched R3: 1.918/0.00019

MRC1 4.397 0.782 0.889 - 0.990 0.832 0.904 Mlig455_060243 {REF} {Length: 4769} {Pfam: Lectin C-type domain [PF00059.23, score=548.8]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=62.0]; Extracellular link domain [PF00193.19, score=22.4]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [RH, Score=513, Expect=2e-156]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [RH, Score=485, Expect=1e-146]} {Dmel: FBgn0035199, tfc, triforce, [Score=57.4, Expect=8e-09]} {Celegans: WBGene00020191, clec-53, C-type LECtin, [RH, Score=103, Expect=1e-23]} {Smed: dd_Smed_v6_3193_0_2, dd_Smed_v6_3193_0_2, [Score=209, Expect=1e-54]} {RNA1509_169} {RNA1310_579} {RNA815_112.1}
14. MligTC455_42341 2131 44.4 Mlig455_015675, Mlig455_062486

Neo: -

Age: logFC(26M/2M)=-0.307

Region-enriched R3: 2.018/0.00002

CYB561A3 4.394 0.788 0.927 0.774 0.969 0.936 -

Mlig455_015675 {REF} {Length: 1331} {Pfam: Eukaryotic cytochrome b561 [PF03188.18, score=116.0]} {Human: ENSG00000162144, CYB561A3, cytochrome b561 family member A3, [Score=123, Expect=1e-33]} {Mouse: ENSMUSG00000034445, Cyb561a3, cytochrome b561 family, member A3, [Score=126, Expect=4e-35]} {Dmel: FBgn0035321, CG1275, [Score=86.3, Expect=4e-20]} {Celegans: WBGene00018210, F39G3.5, [RH, Score=87.4, Expect=1e-20]} {Smed: dd_Smed_v6_4017_0_1, dd_Smed_v6_4017_0_1, [Score=118, Expect=2e-32]} {RNA1509_29638} {RNA1310_17515.1} {RNA815_8047}

Mlig455_062486 {REF} {Length: 1632} {Pfam: Eukaryotic cytochrome b561 [PF03188.18, score=113.3]} {Human: ENSG00000162144, CYB561A3, cytochrome b561 family member A3, [Score=122, Expect=5e-34]} {Mouse: ENSMUSG00000034445, Cyb561a3, cytochrome b561 family, member A3, [Score=124, Expect=4e-35]} {Dmel: FBgn0261673, nemy, no extended memory, [Score=83.6, Expect=8e-20]} {Celegans: WBGene00010131, F55H2.5, Putative cytochrome b561, [Score=84.3, Expect=8e-20]} {Smed: dd_Smed_v6_4017_0_1, dd_Smed_v6_4017_0_1, [Score=113, Expect=4e-31]} {RNA1509_29638, RNA1509_6916} {RNA1310_17515.1, RNA1509_29638} {RNA1509_29638, RNA815_8047}
15. MligTC455_45089 554 11.55 Mlig455_050926

Neo: -

Age: -

Region-enriched R3: 2.774/0.00002
Region-enriched R4: 2.768/0.00026
Region-enriched R5: 1.929/0.00929

NAAA 4.352 - 0.851 0.740 0.918 0.954 0.889 Mlig455_050926 {REF} {Length: 1626} {Pfam: beta subunit of N-acylethanolamine-hydrolyzing acid amidase [PF15508.8, score=40.2]; Linear amide C-N hydrolases, choloylglycine hydrolase family [PF02275.20, score=39.6]} {Human: ENSG00000138744, NAAA, N-acylethanolamine acid amidase, [RH, Score=243, Expect=5e-77]} {Mouse: ENSMUSG00000029413, Naaa, N-acylethanolamine acid amidase, [RH, Score=247, Expect=7e-79]} {Celegans: WBGene00021917, Y55D5A.3, [RH, Score=198, Expect=5e-60]} {RNA1509_15029, RNA1509_51698} {RNA1310_22544, RNA1509_15029} {RNA1509_15029, RNA815_9551.1}
16. MligTC455_42150 1601 33.36 Mlig455_031740

Neo: -

Age: -

Region-enriched R3: 1.735/0.01830

4.337 0.734 - 0.872 0.925 0.970 0.836 Mlig455_031740 {REF} {Length: 2276} {Pfam: Lectin C-type domain [PF00059.23, score=29.1]} {Celegans: WBGene00016619, C43H6.6, [Score=48.9, Expect=5e-06]} {RNA1509_9329} {RNA1310_19331.2} {RNA815_8190.1}
17. MligTC455_41984 5794 120.71 Mlig455_070257

Neo: -

Age: logFC(26M/2M)=0.384

Region-enriched R3: 1.830/0.00014
Region-enriched R4: 1.696/0.00265
Region-enriched R6: 1.511/0.01084
Region-enriched R5: 1.493/0.00157

BHMT 4.336 0.860 0.754 - 0.850 0.960 0.912 Mlig455_070257 {REF} {Length: 2300} {Pfam: Homocysteine S-methyltransferase [PF02574.18, score=161.5]} {Human: ENSG00000145692, BHMT, betaine--homocysteine S-methyltransferase, [RH, Score=543, Expect=0.0]} {Mouse: ENSMUSG00000074768, Bhmt, betaine-homocysteine methyltransferase, [RH, Score=548, Expect=0.0]; ENSMUSG00000069324, Gm5096, predicted gene 5096, [RH, Score=548, Expect=0.0]} {Smed: dd_Smed_v6_873_0_1, dd_Smed_v6_873_0_1, [RH, Score=555, Expect=0.0]} {RNA1509_10637, RNA1509_54311, RNA1509_9980} {RNA1310_18981.1, RNA1509_54311, RNA1509_9980} {RNA1509_54311, RNA1509_9980, RNA815_5900.2}
18. MligTC455_51431 4302 89.63 Mlig455_045755

Neo: -

Age: Up-Down-Up

Region-enriched R3: 1.984/0.00149
Region-enriched R5: 1.417/0.02239

4.278 0.779 - 0.826 0.889 0.961 0.823 Mlig455_045755 {REF} {Length: 312} {NoTransDecoderORF} {RNA1509_51873} {RNA1310_8784.1} {RNA815_3564}
19. MligTC455_20358 3816 79.5 Mlig455_051035

Neo: -

Age: logFC(26M/2M)=0.321

Region-enriched R3: 1.944/0.00005
Region-enriched R6: 1.584/0.00678

SLC15A1 4.237 0.723 0.866 0.771 - 0.951 0.926 Mlig455_051035 {REF} {Length: 1758} {Pfam: POT family [PF00854.23, score=33.7]} {Human: ENSG00000088386, SLC15A1, solute carrier family 15 member 1, [Score=85.1, Expect=5e-17]} {Mouse: ENSMUSG00000025557, Slc15a1, solute carrier family 15 (oligopeptide transporter), member 1, [Score=86.7, Expect=1e-17]} {Dmel: FBgn0028491, CG2930, [Score=99.0, Expect=8e-22]} {Celegans: WBGene00003878, pept-3, Peptide transporter 3, [Score=75.5, Expect=2e-14]} {Smed: dd_Smed_v6_4941_0_1, dd_Smed_v6_4941_0_1, [Score=91.7, Expect=1e-19]} {RNA1509_7670} {RNA1310_5104.2} {RNA815_1763.1}
20. MligTC455_27869 8765 182.6 Mlig455_051857, Mlig455_051868, Mlig455_051893

Neo: -

Age: Down-Down-Up

Region-enriched R3: 2.214/0.00040
Region-enriched R5: 1.603/0.01133

ANPEP 4.21 - 0.728 0.835 0.751 0.934 0.962

Mlig455_051857 {REF} {Length: 3680} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=260.1]; Peptidase family M1 domain [PF01433.22, score=238.0]; Peptidase M1 N-terminal domain [PF17900.3, score=137.9]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=560, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [RH, Score=546, Expect=6e-179]} {Dmel: FBgn0039640, CG14516, [RH, Score=536, Expect=1e-174]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=405, Expect=2e-125]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=599, Expect=0.0]} {RNA1509_5196} {RNA1310_2955.1} {RNA815_759.2}

Mlig455_051868 {REF} {Length: 4344} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=259.5]; Peptidase family M1 domain [PF01433.22, score=234.1]; Peptidase M1 N-terminal domain [PF17900.3, score=137.9]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=552, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [Score=542, Expect=4e-177]} {Dmel: FBgn0039640, CG14516, [RH, Score=529, Expect=7e-172]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=406, Expect=1e-125]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=595, Expect=0.0]} {RNA1509_5196} {RNA1310_2955.1} {RNA815_759.2}

Mlig455_051893 {REF} {Length: 4373} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=260.1]; Peptidase family M1 domain [PF01433.22, score=236.2]; Peptidase M1 N-terminal domain [PF17900.3, score=137.9]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=558, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [RH, Score=545, Expect=3e-178]} {Dmel: FBgn0039640, CG14516, [RH, Score=533, Expect=2e-173]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=405, Expect=2e-125]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=596, Expect=0.0]} {RNA1509_5196} {RNA1310_2955.1} {RNA815_759.2}
21. MligTC455_42151 2150 44.78 Mlig455_031754

Neo: -

Age: logFC(26M/2M)=-0.411

Region-enriched R3: 1.586/0.00024
Region-enriched R4: 1.056/0.04463

4.186 0.753 - 0.760 0.954 0.912 0.807 Mlig455_031754 {REF} {Length: 1956} {Pfam: Lectin C-type domain [PF00059.23, score=24.6]} {Celegans: WBGene00016619, C43H6.6, [Score=50.4, Expect=2e-06]} {RNA1509_13408, RNA1509_53962} {RNA1310_19331.1, RNA1509_53962} {RNA1509_53962, RNA815_8190.1}
22. MligTC455_45090 767 15.97 Mlig455_050942

Neo: -

Age: Down-Up-Down

Region-enriched R3: 1.666/0.00039
Region-enriched R4: 1.435/0.01328

NAAA 4.158 0.709 0.845 0.804 0.977 0.823 - Mlig455_050942 {REF} {Length: 1563} {Pfam: beta subunit of N-acylethanolamine-hydrolyzing acid amidase [PF15508.8, score=40.2]; Linear amide C-N hydrolases, choloylglycine hydrolase family [PF02275.20, score=40.0]} {Human: ENSG00000138744, NAAA, N-acylethanolamine acid amidase, [RH, Score=243, Expect=5e-77]} {Mouse: ENSMUSG00000029413, Naaa, N-acylethanolamine acid amidase, [RH, Score=248, Expect=7e-79]} {Celegans: WBGene00021917, Y55D5A.3, [RH, Score=198, Expect=5e-60]} {RNA1509_56673} {RNA1310_22544, RNA1509_56673} {RNA1509_56673, RNA815_9551.1}
23. MligTC455_12590 579 12.06 Mlig455_049883

Neo: -

Age: -

Region-enriched R3: 1.952/0.03324

SLC1A7 4.114 0.761 0.841 - 0.758 0.954 0.800 Mlig455_049883 {REF} {Length: 2234} {Pfam: Sodium:dicarboxylate symporter family [PF00375.20, score=406.4]} {Human: ENSG00000162383, SLC1A7, solute carrier family 1 member 7, [RH, Score=442, Expect=7e-150]; ENSG00000106688, SLC1A1, solute carrier family 1 member 1, [RH, Score=427, Expect=7e-145]} {Mouse: ENSMUSG00000024935, Slc1a1, solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1, [RH, Score=446, Expect=5e-152]} {Dmel: FBgn0026439, Eaat1, Excitatory amino acid transporter 1, [RH, Score=364, Expect=6e-121]} {Celegans: WBGene00001620, glt-1, Excitatory amino acid transporter, [Score=428, Expect=1e-145]} {Smed: dd_Smed_v6_1106_0_1, dd_Smed_v6_1106_0_1, [Score=449, Expect=2e-154]} {RNA1509_28921, RNA1509_5225} {RNA1310_19422.1, RNA1509_28921, RNA1509_5225} {RNA1509_28921, RNA1509_5225, RNA815_7338}
24. MligTC455_37064 5158 107.45 Mlig455_024253, Mlig455_051570, Mlig455_055809

Neo: -

Age: logFC(26M/2M)=-0.286

SDK2 4.09 - 0.844 0.959 0.754 0.717 0.816

Mlig455_024253 {REF} {Length: 1808} {Pfam: Oxidoreductase family, C-terminal alpha/beta domain [PF02894.19, score=72.8]; Oxidoreductase family, NAD-binding Rossmann fold [PF01408.24, score=63.3]} {Smed: dd_Smed_v6_1689_0_1, dd_Smed_v6_1689_0_1, [RH, Score=278, Expect=4e-92]} {RNA1509_16223, RNA1509_19677, RNA1509_25441} {RNA1310_22108, RNA1509_16223, RNA1509_19677, RNA1509_25441} {RNA1509_16223, RNA1509_19677, RNA1509_25441, RNA815_9104.1}

Mlig455_051570 {REF} {Length: 4440} {Pfam: Fibronectin type III domain [PF00041.23, score=232.6]; Immunoglobulin I-set domain [PF07679.18, score=85.9]; Immunoglobulin domain [PF13927.8, score=72.1]; Purple acid Phosphatase, N-terminal domain [PF16656.7, score=71.8]; Immunoglobulin V-set domain [PF07686.19, score=42.6]; Immunoglobulin domain [PF13895.8, score=38.3]; Immunoglobulin domain [PF00047.27, score=35.2]; Glycosyl hydrolase family 36 C-terminal domain [PF16874.7, score=20.9]} {Human: ENSG00000069188, SDK2, sidekick cell adhesion molecule 2, [Score=330, Expect=4e-92]} {Mouse: ENSMUSG00000041592, Sdk2, sidekick cell adhesion molecule 2, [Score=325, Expect=1e-90]} {Dmel: FBgn0021764, sdk, sidekick, [Score=311, Expect=3e-86]} {Celegans: WBGene00004371, rig-4, Protein sidekick homolog, [Score=245, Expect=2e-65]} {Smed: dd_Smed_v6_4031_0_1, dd_Smed_v6_4031_0_1, [Score=134, Expect=1e-31]} {RNA1509_37157} {RNA1310_10115} {RNA815_23017}

Mlig455_055809 {REF} {Length: 1657} {Pfam: Oxidoreductase family, C-terminal alpha/beta domain [PF02894.19, score=72.1]; Oxidoreductase family, NAD-binding Rossmann fold [PF01408.24, score=63.2]} {Smed: dd_Smed_v6_1689_0_1, dd_Smed_v6_1689_0_1, [RH, Score=281, Expect=5e-93]} {RNA1509_24086, RNA1509_27967, RNA1509_31849} {RNA1310_22108, RNA1509_24086, RNA1509_27967, RNA1509_31849} {RNA1509_24086, RNA1509_27967, RNA1509_31849, RNA815_9104.1}
25. MligTC455_38469 2237 46.61 Mlig455_028190, Mlig455_063554

Neo: -

Age: logFC(26M/2M)=0.551

Region-enriched R4: 2.765/0.00002
Region-enriched R3: 2.517/0.00000
Region-enriched R5: 1.859/0.00156

MFSD2A 3.665 0.840 0.866 - 0.974 0.985 -

Mlig455_028190 {REF} {Length: 1877} {Pfam: MFS/sugar transport protein [PF13347.8, score=314.5]; Major Facilitator Superfamily [PF07690.18, score=35.3]} {Human: ENSG00000168389, MFSD2A, major facilitator superfamily domain containing 2A, [RH, Score=317, Expect=2e-101]} {Mouse: ENSMUSG00000028655, Mfsd2a, major facilitator superfamily domain containing 2A, [RH, Score=312, Expect=2e-99]} {Smed: dd_Smed_v6_11210_0_1, dd_Smed_v6_11210_0_1, [RH, Score=380, Expect=3e-126]} {RNA1509_5264} {RNA1310_14549} {RNA815_5531}

Mlig455_063554 {REF} {Length: 2339} {Pfam: MFS/sugar transport protein [PF13347.8, score=217.9]; Major Facilitator Superfamily [PF07690.18, score=39.9]} {Human: ENSG00000168389, MFSD2A, major facilitator superfamily domain containing 2A, [RH, Score=223, Expect=1e-68]} {Mouse: ENSMUSG00000037336, Mfsd2b, major facilitator superfamily domain containing 2B, [RH, Score=212, Expect=2e-64]} {Smed: dd_Smed_v6_11210_0_1, dd_Smed_v6_11210_0_1, [Score=274, Expect=8e-87]} {RNA1509_5264} {RNA1310_14549} {RNA815_5531}
26. MligTC455_37239 1846 38.46 Mlig455_060082

Neo: -

Age: -

Region-enriched R3: 1.562/0.04763
Region-enriched R5: 1.292/0.04648

PANK4 3.664 0.880 0.842 0.973 0.969 - - Mlig455_060082 {REF} {Length: 1532} {Pfam: Fumble [PF03630.16, score=120.5]} {Human: ENSG00000273494, PANK4, pantothenate kinase 4, [Score=106, Expect=2e-24]; ENSG00000157881, PANK4, pantothenate kinase 4, [Score=106, Expect=2e-24]} {Mouse: ENSMUSG00000029056, Pank4, pantothenate kinase 4, [Score=97.4, Expect=1e-21]} {Dmel: FBgn0011205, fbl, fumble, [Score=66.2, Expect=7e-12]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [Score=170, Expect=1e-49]} {RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233} {RNA1310_20224, RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233} {RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233, RNA815_7673}
27. MligTC455_20726 1772 36.91 Mlig455_035274

Neo: -

Age: -

Region-enriched R3: 2.119/0.00009

SLC1A6 3.626 - 0.851 - 0.959 0.907 0.909 Mlig455_035274 {REF} {Length: 2086} {Pfam: Sodium:dicarboxylate symporter family [PF00375.20, score=422.3]} {Human: ENSG00000105143, SLC1A6, solute carrier family 1 member 6, [RH, Score=462, Expect=9e-158]} {Mouse: ENSMUSG00000024935, Slc1a1, solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1, [RH, Score=457, Expect=3e-156]; ENSMUSG00000005357, Slc1a6, solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6, [RH, Score=452, Expect=6e-154]} {Dmel: FBgn0026439, Eaat1, Excitatory amino acid transporter 1, [RH, Score=373, Expect=4e-124]} {Celegans: WBGene00001620, glt-1, Excitatory amino acid transporter, [Score=421, Expect=6e-143]} {Smed: dd_Smed_v6_1106_0_1, dd_Smed_v6_1106_0_1, [Score=427, Expect=2e-145]} {RNA1509_5272, RNA1509_57758, RNA1509_7401} {RNA1310_8553.1, RNA1509_5272, RNA1509_57758} {RNA1509_5272, RNA1509_57758, RNA815_2974.1}
28. MligTC455_42224 691 14.4 Mlig455_012381, Mlig455_012802

Neo: -

Age: logFC(26M/2M)=-0.411

Region-enriched R4: 3.746/0.00086
Region-enriched R3: 3.098/0.00277

ENTPD6 3.592 - 0.808 - 0.978 0.861 0.945

Mlig455_012381 {REF} {Length: 2018} {Pfam: GDA1/CD39 (nucleoside phosphatase) family [PF01150.19, score=209.9]; Ppx/GppA phosphatase family [PF02541.18, score=18.1]} {Human: ENSG00000197586, ENTPD6, ectonucleoside triphosphate diphosphohydrolase 6 (putative), [Score=196, Expect=9e-57]} {Mouse: ENSMUSG00000033068, Entpd6, ectonucleoside triphosphate diphosphohydrolase 6, [Score=196, Expect=5e-57]; ENSMUSG00000021236, Entpd5, ectonucleoside triphosphate diphosphohydrolase 5, [Score=189, Expect=2e-54]} {Dmel: FBgn0024947, NTPase, [Score=165, Expect=8e-46]} {Celegans: WBGene00010697, uda-1, Nucleoside-diphosphatase uda-1, [Score=144, Expect=6e-38]} {Smed: dd_Smed_v6_8855_0_2, dd_Smed_v6_8855_0_2, [Score=178, Expect=8e-51]} {RNA1509_19635, RNA1509_40383, RNA1509_54757} {RNA1310_14737, RNA1509_19635, RNA1509_40383, RNA1509_54757} {RNA1509_19635, RNA1509_40383, RNA1509_54757, RNA815_6957}

Mlig455_012802 {REF} {Length: 1599} {Pfam: GDA1/CD39 (nucleoside phosphatase) family [PF01150.19, score=124.4]; Ppx/GppA phosphatase family [PF02541.18, score=18.4]} {Human: ENSG00000197586, ENTPD6, ectonucleoside triphosphate diphosphohydrolase 6 (putative), [Score=138, Expect=7e-36]; ENSG00000187097, ENTPD5, ectonucleoside triphosphate diphosphohydrolase 5, [Score=134, Expect=9e-35]} {Mouse: ENSMUSG00000033068, Entpd6, ectonucleoside triphosphate diphosphohydrolase 6, [Score=138, Expect=3e-36]; ENSMUSG00000021236, Entpd5, ectonucleoside triphosphate diphosphohydrolase 5, [Score=132, Expect=3e-34]} {Dmel: FBgn0024947, NTPase, [Score=118, Expect=5e-29]} {Celegans: WBGene00010697, uda-1, Nucleoside-diphosphatase uda-1, [Score=95.1, Expect=4e-21]} {Smed: dd_Smed_v6_8855_0_2, dd_Smed_v6_8855_0_2, [Score=120, Expect=3e-30]} {RNA1509_40383, RNA1509_51501} {RNA1310_14737, RNA1509_51501} {RNA1509_51501, RNA815_6957}
29. MligTC455_19022 687 14.31 Mlig455_037405

Neo: -

Age: -

Region-enriched R3: 1.615/0.00300
Region-enriched R5: 1.137/0.02464

GRINA 3.519 0.816 - - 0.902 0.841 0.960 Mlig455_037405 {REF} {Length: 2190} {Pfam: Inhibitor of apoptosis-promoting Bax1 [PF01027.22, score=72.3]} {Human: ENSG00000178719, GRINA, glutamate ionotropic receptor NMDA type subunit associated protein 1, [Score=163, Expect=3e-47]} {Mouse: ENSMUSG00000022564, Grina, glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding), [Score=145, Expect=4e-41]; ENSMUSG00000023011, Faim2, Fas apoptotic inhibitory molecule 2, [Score=144, Expect=8e-41]} {Dmel: FBgn0013305, Nmda1, N-methyl-D-aspartate receptor-associated protein, [Score=155, Expect=6e-45]} {Celegans: WBGene00006470, tag-120, [Score=111, Expect=4e-29]} {Smed: dd_Smed_v6_1586_0_1, dd_Smed_v6_1586_0_1, [Score=171, Expect=9e-52]} {RNA1509_32288} {RNA1310_27497.1, RNA1509_32288} {RNA1509_32288, RNA815_12093}
30. MligTC455_40682 2549 53.1 Mlig455_013284, Mlig455_035928

Neo: -

Age: -

Region-enriched R3: 1.724/0.00155
Region-enriched R4: 1.452/0.02174
Region-enriched R5: 1.104/0.04518

3.514 0.705 - - 0.976 0.908 0.925

Mlig455_013284 {REF} {Length: 2073} {Pfam: Tctex-1 family [PF03645.15, score=31.9]} {Mouse: ENSMUSG00000079710, Gm3448, predicted gene 3448, [Score=50.1, Expect=3e-07]; ENSMUSG00000079707, Tcte3, t-complex-associated testis expressed 3, [Score=50.1, Expect=3e-07]; ENSMUSG00000116780, Gm3417, predicted gene 3417, [Score=48.9, Expect=6e-07]} {Smed: dd_Smed_v6_12108_0_1, dd_Smed_v6_12108_0_1, [Score=57.8, Expect=2e-10]} {RNA1509_11021, RNA1509_22678} {RNA1310_29221, RNA1509_11021, RNA1509_22678} {RNA1509_11021, RNA1509_22678, RNA815_16910}

Mlig455_035928 {REF} {Length: 1424} {Pfam: Tctex-1 family [PF03645.15, score=31.7]} {Mouse: ENSMUSG00000079707, Tcte3, t-complex-associated testis expressed 3, [Score=49.7, Expect=4e-07]; ENSMUSG00000079710, Gm3448, predicted gene 3448, [Score=49.7, Expect=4e-07]; ENSMUSG00000116780, Gm3417, predicted gene 3417, [Score=48.5, Expect=9e-07]} {Smed: dd_Smed_v6_12108_0_1, dd_Smed_v6_12108_0_1, [Score=58.5, Expect=1e-10]} {RNA1509_11021, RNA1509_38233} {RNA1310_29221, RNA1509_38233} {RNA1509_38233, RNA815_16910}
31. MligTC455_35949 279 5.81 Mlig455_011030

Neo: -

Age: -

Region-enriched R3: 2.439/0.03369
Region-enriched R5: 2.149/0.02386

DIRC2 3.503 0.794 - 0.852 0.976 0.881 - Mlig455_011030 {REF} {Length: 1623} {TRANSSPLICED} {Pfam: Major Facilitator Superfamily [PF07690.18, score=70.1]} {Human: ENSG00000138463, DIRC2, disrupted in renal carcinoma 2, [RH, Score=194, Expect=4e-56]} {Mouse: ENSMUSG00000022848, Dirc2, disrupted in renal carcinoma 2 (human), [RH, Score=197, Expect=1e-57]} {Celegans: WBGene00015632, C09D4.1, Uncharacterized MFS-type transporter C09D4.1, [Score=102, Expect=2e-23]} {Smed: dd_Smed_v6_12577_0_1, dd_Smed_v6_12577_0_1, [Score=145, Expect=9e-39]} {RNA1509_19444} {RNA1310_8463, RNA1509_19444} {RNA1509_19444, RNA815_7671}
32. MligTC455_45742 2132 44.42 Mlig455_003184, Mlig455_003387

Neo: -

Age: logFC(26M/2M)=0.345

Region-specific R4: 3.405
Region-specific R3: 3.388

Region-enriched R4: 3.484/0.00000
Region-enriched R3: 2.393/0.00000
Region-enriched R5: 1.235/0.00412

SLC22A4, SLC22A5 3.502 - 0.869 - 0.967 0.724 0.942

Mlig455_003184 {REF} {Length: 2170} {Pfam: Sugar (and other) transporter [PF00083.26, score=102.2]; Major Facilitator Superfamily [PF07690.18, score=60.9]} {Human: ENSG00000197208, SLC22A4, solute carrier family 22 member 4, [Score=274, Expect=4e-84]; ENSG00000197375, SLC22A5, solute carrier family 22 member 5, [Score=274, Expect=7e-84]} {Mouse: ENSMUSG00000063652, Slc22a21, solute carrier family 22 (organic cation transporter), member 21, [Score=278, Expect=1e-85]} {Dmel: FBgn0019952, Orct, Organic cation transporter, [Score=285, Expect=2e-88]} {Celegans: WBGene00003842, oct-1, Organic cation transporter 1, [Score=240, Expect=4e-71]} {Smed: dd_Smed_v6_10826_0_2, dd_Smed_v6_10826_0_2, [Score=198, Expect=7e-56]} {RNA1509_40645} {RNA1310_12725.1} {RNA815_4270}

Mlig455_003387 {REF} {Length: 2455} {Pfam: Sugar (and other) transporter [PF00083.26, score=70.5]; Major Facilitator Superfamily [PF07690.18, score=57.3]} {Human: ENSG00000197375, SLC22A5, solute carrier family 22 member 5, [Score=154, Expect=6e-42]; ENSG00000197208, SLC22A4, solute carrier family 22 member 4, [Score=147, Expect=2e-39]} {Mouse: ENSMUSG00000063652, Slc22a21, solute carrier family 22 (organic cation transporter), member 21, [Score=154, Expect=6e-42]} {Dmel: FBgn0019952, Orct, Organic cation transporter, [Score=174, Expect=1e-49]} {Celegans: WBGene00003843, oct-2, Organic Cation Transporter; Organic cation transporter, [Score=113, Expect=2e-27]} {Smed: dd_Smed_v6_10826_0_2, dd_Smed_v6_10826_0_2, [Score=116, Expect=1e-28]} {RNA1509_11765, RNA1509_40645} {RNA1310_12725.1, RNA1509_11765} {RNA1509_11765, RNA815_4270}
33. MligTC455_52040 2198 45.8 Mlig455_029597

Neo: Germline

Age: logFC(26M/2M)=0.256

Region-enriched R3: 1.723/0.00072
Region-enriched R5: 1.481/0.00114

VIL1 3.485 0.714 0.835 - 0.982 0.954 - Mlig455_029597 {REF} {Length: 2577} {Pfam: Gelsolin repeat [PF00626.24, score=113.7]} {Human: ENSG00000127831, VIL1, villin 1, [Score=182, Expect=5e-53]; ENSG00000148180, GSN, gelsolin, [Score=179, Expect=1e-49]; ENSG00000135407, AVIL, advillin, [Score=174, Expect=1e-47]} {Mouse: ENSMUSG00000026879, Gsn, gelsolin, [Score=185, Expect=7e-52]; ENSMUSG00000026175, Vil1, villin 1, [Score=182, Expect=1e-50]} {Dmel: FBgn0010225, Gel, Gelsolin, [Score=194, Expect=3e-55]} {Celegans: WBGene00010593, gsnl-1, Gelsolin-like protein 1, [Score=164, Expect=4e-46]} {Smed: dd_Smed_v6_1215_0_1, dd_Smed_v6_1215_0_1, [RH, Score=403, Expect=3e-140]} {RNA1509_12411, RNA1509_17911, RNA1509_2858, RNA1509_30271, RNA1509_44412, RNA1509_44633} {RNA1310_15610, RNA1509_12411, RNA1509_17911, RNA1509_2858, RNA1509_30271, RNA1509_44412, RNA1509_44633} {RNA1509_12411, RNA1509_17911, RNA1509_2858, RNA1509_30271, RNA1509_44412, RNA1509_44633, RNA815_7841}
34. MligTC455_24112 7326 152.63 Mlig455_006637, Mlig455_070643

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.380

CYP2D6, CYP2U1 3.482 - 0.796 0.905 0.970 0.811 -

Mlig455_006637 {REF} {Length: 1777} {Pfam: Cytochrome P450 [PF00067.24, score=343.6]} {Human: ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=263, Expect=7e-81]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [RH, Score=263, Expect=2e-81]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [RH, Score=260, Expect=2e-80]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [RH, Score=259, Expect=4e-80]; ENSG00000275211, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=2e-79]; ENSG00000283284, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=1e-79]; ENSG00000100197, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=3e-79]; ENSG00000280905, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]; ENSG00000272532, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]; ENSG00000272000, AC236040.1, cytochrome P450 family 2 subfamily D member 6 pseudogene, [RH, Score=257, Expect=4e-79]; ENSG00000282966, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]} {Mouse: ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=285, Expect=3e-90]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [RH, Score=283, Expect=1e-89]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=278, Expect=2e-87]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=273, Expect=2e-85]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=271, Expect=8e-85]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=271, Expect=1e-84]} {Dmel: FBgn0001992, Cyp303a1, [RH, Score=207, Expect=1e-60]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [RH, Score=292, Expect=3e-93]} {RNA1509_10420} {RNA1310_15091.1} {RNA815_4606.2}

Mlig455_070643 {REF} {Length: 2371} {Pfam: Cytochrome P450 [PF00067.24, score=337.1]} {Human: ENSG00000283284, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=261, Expect=1e-80]; ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=260, Expect=7e-80]; ENSG00000275211, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=260, Expect=2e-80]; ENSG00000282966, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000272000, AC236040.1, cytochrome P450 family 2 subfamily D member 6 pseudogene, [RH, Score=259, Expect=3e-80]; ENSG00000272532, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000280905, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000100197, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [RH, Score=256, Expect=6e-79]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [RH, Score=254, Expect=3e-78]} {Mouse: ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=280, Expect=2e-88]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [RH, Score=279, Expect=7e-88]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=275, Expect=3e-86]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=268, Expect=1e-83]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=268, Expect=1e-83]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=266, Expect=7e-83]} {Dmel: FBgn0001992, Cyp303a1, [RH, Score=201, Expect=4e-58]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [RH, Score=288, Expect=2e-91]} {RNA1509_10420, RNA1509_36519} {RNA1310_15091.1, RNA1509_10420, RNA1509_36519} {RNA1509_10420, RNA1509_36519, RNA815_4606.2}
35. MligTC455_52041 2170 45.21 Mlig455_029621

Neo: -

Age: logFC(26M/2M)=0.515

Region-enriched R3: 1.780/0.00221
Region-enriched R5: 1.483/0.00437

SCIN 3.476 0.711 0.837 - 0.981 0.947 - Mlig455_029621 {REF} {Length: 1419} {Pfam: Gelsolin repeat [PF00626.24, score=61.4]} {Human: ENSG00000006747, SCIN, scinderin, [Score=78.6, Expect=3e-15]} {Mouse: ENSMUSG00000002565, Scin, scinderin, [Score=82.8, Expect=7e-17]} {Dmel: FBgn0010225, Gel, Gelsolin, [Score=76.6, Expect=7e-15]} {Smed: dd_Smed_v6_1215_0_1, dd_Smed_v6_1215_0_1, [Score=214, Expect=8e-67]} {RNA1509_17911} {RNA1310_15610} {RNA815_7841}
36. MligTC455_49659 4741 98.77 Mlig455_011512, Mlig455_050003

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.314

Region-enriched R3: 1.923/0.00380

3.466 0.795 0.814 - 0.971 0.886 -

Mlig455_011512 {REF} {Length: 2299} {RNA1509_3964} {RNA1310_32368} {RNA815_14237.1}

Mlig455_050003 {REF} {Length: 1812} {RNA1509_3964} {RNA1310_32368} {RNA815_14237.1}
37. MligTC455_12517 587 12.23 Mlig455_023517

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-1.412

3.465 - 0.773 - 0.962 0.808 0.922 Mlig455_023517 {REF} {Length: 661} {RNA1509_22223} {RNA1310_60769} {RNA815_31256}
38. MligTC455_44700 2825 58.85 Mlig455_049079

Neo: -

Age: -

Region-enriched R3: 1.667/0.02565

SLC10A1 3.454 0.760 0.818 - 0.976 0.900 - Mlig455_049079 {REF} {Length: 2131} {Pfam: Sodium Bile acid symporter family [PF01758.18, score=117.8]; SBF-like CPA transporter family (DUF4137) [PF13593.8, score=36.6]} {Human: ENSG00000100652, SLC10A1, solute carrier family 10 member 1, [RH, Score=124, Expect=4e-31]} {Mouse: ENSMUSG00000023073, Slc10a2, solute carrier family 10, member 2, [Score=131, Expect=1e-33]} {Dmel: FBgn0030638, CG11655, [Score=154, Expect=2e-41]} {Celegans: WBGene00044650, Y71G10AR.4, [RH, Score=202, Expect=9e-59]} {Smed: dd_Smed_v6_11330_0_1, dd_Smed_v6_11330_0_1, [RH, Score=297, Expect=9e-96]} {RNA1509_41454} {RNA1310_15046, RNA1509_41454} {RNA1509_41454, RNA815_3102}
39. MligTC455_15832 1195 24.9 Mlig455_048167

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.477

Region-enriched R4: 1.763/0.00304
Region-enriched R3: 1.641/0.00124
Region-enriched R5: 1.086/0.02606

3.452 - 0.853 0.902 0.954 0.743 - Mlig455_048167 {REF} {Length: 3287} {Dmel: FBgn0033252, CG12769, [Score=60.1, Expect=2e-09]} {RNA1509_7124} {RNA1310_24518, RNA1509_7124} {RNA1509_7124, RNA815_12801}
40. MligTC455_26167 4416 92 Mlig455_001635

Neo: -

Age: -

Region-enriched R3: 1.339/0.03044

TUBB2B 3.427 0.789 0.865 - 0.952 - 0.821 Mlig455_001635 {REF} {Length: 2122} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=239.0]; Tubulin C-terminal domain [PF03953.19, score=140.8]; Misato Segment II tubulin-like domain [PF10644.11, score=23.2]} {Human: ENSG00000137285, TUBB2B, tubulin beta 2B class IIb, [Score=814, Expect=0.0]; ENSG00000137267, TUBB2A, tubulin beta 2A class IIa, [Score=812, Expect=0.0]; ENSG00000196230, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000227739, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000235067, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000232421, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000224156, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000229684, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000183311, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000232575, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000188229, TUBB4B, tubulin beta 4B class IVb, [Score=811, Expect=0.0]; ENSG00000258947, TUBB3, tubulin beta 3 class III, [Score=803, Expect=0.0]; ENSG00000104833, TUBB4A, tubulin beta 4A class IVa, [Score=802, Expect=0.0]; ENSG00000176014, TUBB6, tubulin beta 6 class V, [Score=784, Expect=0.0]; ENSG00000261456, TUBB8, tubulin beta 8 class VIII, [Score=775, Expect=0.0]} {Mouse: ENSMUSG00000001473, Tubb6, tubulin, beta 6 class V, [RH, Score=788, Expect=0.0]} {Dmel: FBgn0284243, betaTub56D, beta-Tubulin at 56D, [Score=773, Expect=0.0]} {Celegans: WBGene00006537, tbb-2, Tubulin beta-2 chain, [Score=781, Expect=0.0]} {Smed: dd_Smed_v6_83_0_3, dd_Smed_v6_83_0_3, [Score=817, Expect=0.0]} {RNA1509_15718, RNA1509_19379, RNA1509_19747, RNA1509_30988, RNA1509_36839, RNA1509_41622, RNA1509_5016} {RNA1310_13968.2, RNA1509_15718, RNA1509_19379, RNA1509_19747, RNA1509_30988, RNA1509_36839, RNA1509_41622, RNA1509_5016} {RNA1509_15718, RNA1509_19379, RNA1509_19747, RNA1509_30988, RNA1509_36839, RNA1509_41622, RNA1509_5016, RNA815_1610.4}
41. MligTC455_37843 1027 21.4 Mlig455_036229

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.713

Region-enriched R4: 2.635/0.00618
Region-enriched R5: 2.090/0.01009

3.399 0.717 - - 0.956 0.862 0.864 Mlig455_036229 {REF} {Length: 3170} {RNA1509_37071} {RNA1310_75243} {RNA815_10582}
42. MligTC455_19213 332 6.92 Mlig455_027303

Neo: -

Age: -

Region-enriched R4: 3.653/0.00406
Region-enriched R3: 2.959/0.01217
Region-enriched R5: 2.470/0.02256

HSD11B1 3.391 - 0.758 0.815 0.960 0.858 - Mlig455_027303 {REF} {Length: 1227} {Pfam: short chain dehydrogenase [PF00106.27, score=127.7]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=83.9]; KR domain [PF08659.12, score=25.0]} {Human: ENSG00000117594, HSD11B1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=161, Expect=2e-47]} {Mouse: ENSMUSG00000016194, Hsd11b1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=151, Expect=1e-43]} {Dmel: FBgn0051548, CG31548, [Score=79.7, Expect=4e-17]} {Celegans: WBGene00019885, R05D8.7, [Score=80.1, Expect=3e-17]} {Smed: dd_Smed_v6_4614_0_1, dd_Smed_v6_4614_0_1, [Score=72.4, Expect=1e-14]} {RNA1509_41682} {RNA1310_27439} {RNA815_13316}
43. MligTC455_43406 1382 28.79 Mlig455_063546

Neo: -

Age: logFC(26M/2M)=-0.363

Region-enriched R4: 1.356/0.01589
Region-enriched R3: 1.139/0.04629

TRPA1 3.374 - 0.771 0.714 0.987 0.902 - Mlig455_063546 {REF} {Length: 5889} {Pfam: Ion transport protein [PF00520.33, score=52.1]; Ankyrin repeat [PF00023.32, score=19.5]} {Human: ENSG00000104321, TRPA1, transient receptor potential cation channel subfamily A member 1, [Score=130, Expect=7e-30]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=127, Expect=5e-29]} {Dmel: FBgn0035934, TrpA1, Transient receptor potential cation channel A1, [Score=139, Expect=6e-33]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=153, Expect=2e-37]} {Smed: dd_Smed_v6_6201_0_2, dd_Smed_v6_6201_0_2, [Score=132, Expect=7e-31]} {RNA1509_21433, RNA1509_40381, RNA1509_43070, RNA1509_46763} {RNA1310_1768.1, RNA1509_21433, RNA1509_40381, RNA1509_43070} {RNA1509_21433, RNA1509_40381, RNA1509_43070, RNA815_3153}
44. MligTC455_18925 1222 25.47 Mlig455_034430

Neo: -

Age: Down-Up-Down

Region-enriched R4: 1.749/0.00485

RGS12 3.365 0.707 0.748 - 0.966 0.944 - Mlig455_034430 {REF} {Length: 1569} {Pfam: Regulator of G protein signaling domain [PF00615.21, score=98.3]} {Human: ENSG00000159788, RGS12, regulator of G protein signaling 12, [Score=112, Expect=3e-26]; ENSG00000169220, RGS14, regulator of G protein signaling 14, [Score=110, Expect=6e-26]} {Mouse: ENSMUSG00000052087, Rgs14, regulator of G-protein signaling 14, [RH, Score=114, Expect=2e-27]} {Dmel: FBgn0020278, loco, locomotion defects, [Score=99.4, Expect=3e-22]} {Celegans: WBGene00004347, rgs-4, Regulator of G protein Signaling, [Score=82.8, Expect=3e-18]} {Smed: dd_Smed_v6_3873_0_1, dd_Smed_v6_3873_0_1, [Score=95.5, Expect=3e-23]} {RNA1509_7258} {RNA1310_21231} {RNA815_8874}
45. MligTC455_24083 6997 145.77 Mlig455_007319

Neo: -

Age: -

Region-enriched R3: 2.037/0.00010
Region-enriched R5: 1.165/0.04106

ACHE 3.358 0.763 0.892 0.733 - 0.970 - Mlig455_007319 {REF} {Length: 2399} {Pfam: Carboxylesterase family [PF00135.30, score=344.4]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=233, Expect=9e-68]} {Mouse: ENSMUSG00000023328, Ache, acetylcholinesterase, [Score=225, Expect=3e-65]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=183, Expect=6e-50]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=228, Expect=1e-66]} {Smed: dd_Smed_v6_4800_0_1, dd_Smed_v6_4800_0_1, [Score=184, Expect=4e-50]} {RNA1509_195, RNA1509_4270, RNA1509_51012} {RNA1310_9229, RNA1509_4270, RNA1509_51012} {RNA1509_4270, RNA1509_51012, RNA815_3141.1}
46. MligTC455_30314 17741 369.6 Mlig455_014122, Mlig455_014131

Neo: -

Age: -

Region-enriched R3: 1.904/0.00059

TUBB4B 3.343 0.743 0.804 - 0.952 - 0.844

Mlig455_014122 {REF} {Length: 2342} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=235.9]; Tubulin C-terminal domain [PF03953.19, score=141.7]; Misato Segment II tubulin-like domain [PF10644.11, score=24.4]} {Human: ENSG00000188229, TUBB4B, tubulin beta 4B class IVb, [RH, Score=913, Expect=0.0]} {Mouse: ENSMUSG00000036752, Tubb4b, tubulin, beta 4B class IVB, [RH, Score=913, Expect=0.0]} {Dmel: FBgn0284243, betaTub56D, beta-Tubulin at 56D, [RH, Score=854, Expect=0.0]} {Celegans: WBGene00006538, tbb-4, Tubulin beta-4 chain, [RH, Score=856, Expect=0.0]} {Smed: dd_Smed_v6_83_0_3, dd_Smed_v6_83_0_3, [RH, Score=910, Expect=0.0]} {RNA1509_24313, RNA1509_3450, RNA1509_35816, RNA1509_47714, RNA1509_5200, RNA1509_7269} {RNA1310_15130.1, RNA1509_24313, RNA1509_3450, RNA1509_35816, RNA1509_47714, RNA1509_5200, RNA1509_7269} {RNA1509_24313, RNA1509_3450, RNA1509_35816, RNA1509_47714, RNA1509_5200, RNA1509_7269, RNA815_1610.1}

Mlig455_014131 {REF} {Length: 2057} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=235.8]; Tubulin C-terminal domain [PF03953.19, score=143.3]; Misato Segment II tubulin-like domain [PF10644.11, score=24.4]} {Human: ENSG00000188229, TUBB4B, tubulin beta 4B class IVb, [RH, Score=913, Expect=0.0]} {Mouse: ENSMUSG00000036752, Tubb4b, tubulin, beta 4B class IVB, [RH, Score=913, Expect=0.0]} {Dmel: FBgn0284243, betaTub56D, beta-Tubulin at 56D, [RH, Score=854, Expect=0.0]} {Celegans: WBGene00006538, tbb-4, Tubulin beta-4 chain, [RH, Score=856, Expect=0.0]} {Smed: dd_Smed_v6_83_0_1, dd_Smed_v6_83_0_1, [RH, Score=910, Expect=0.0]} {RNA1509_10060, RNA1509_16564, RNA1509_30077, RNA1509_51924, RNA1509_5235, RNA1509_54023, RNA1509_5590, RNA1509_7735} {RNA1310_15130.1, RNA1509_10060, RNA1509_16564, RNA1509_30077, RNA1509_51924, RNA1509_5235, RNA1509_54023, RNA1509_5590, RNA1509_7735} {RNA1509_10060, RNA1509_16564, RNA1509_30077, RNA1509_51924, RNA1509_5235, RNA1509_54023, RNA1509_5590, RNA1509_7735, RNA815_1610.1}
47. MligTC455_35217 5138 107.05 Mlig455_014282, Mlig455_014335

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.399

Region-enriched R3: 1.348/0.01129

3.342 0.884 0.709 - 0.961 0.788 -

Mlig455_014282 {REF} {Length: 1807} {TRANSSPLICED} {Pfam: Transferase family [PF02458.17, score=158.0]} {RNA1509_22501, RNA1509_4768} {RNA1310_7742.1, RNA1509_22501} {RNA1509_22501, RNA815_6411}

Mlig455_014335 {REF} {Length: 1769} {TRANSSPLICED} {Pfam: Transferase family [PF02458.17, score=159.5]} {RNA1509_4768} {RNA1310_7742.1} {RNA815_6411}
48. MligTC455_42353 5099 106.23 Mlig455_014274, Mlig455_014309, Mlig455_018673

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.786

Region-enriched R3: 2.226/0.00003

AC113554.1, ACE 3.331 0.762 0.839 0.776 0.954 - -

Mlig455_014274 {REF} {Length: 2949} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=705.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0016122, Acer, Angiotensin-converting enzyme-related, [RH, Score=426, Expect=4e-141]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=191, Expect=3e-51]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=411, Expect=1e-135]} {RNA1509_37062, RNA1509_441} {RNA1310_8949, RNA1509_37062} {RNA1509_37062, RNA815_4061}

Mlig455_014309 {REF} {Length: 2926} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=705.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0016122, Acer, Angiotensin-converting enzyme-related, [RH, Score=426, Expect=4e-141]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=191, Expect=3e-51]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=411, Expect=1e-135]} {RNA1509_441} {RNA1310_8949} {RNA815_4061}

Mlig455_018673 {REF} {Length: 833} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=122.4]} {Human: ENSG00000264813, AC113554.1, novel transcript, [Score=103, Expect=3e-24]; ENSG00000159640, ACE, angiotensin I converting enzyme, [Score=103, Expect=2e-24]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [Score=97.8, Expect=2e-22]; ENSMUSG00000101605, Ace3, angiotensin I converting enzyme (peptidyl-dipeptidase A) 3, [Score=93.2, Expect=6e-21]} {Dmel: FBgn0012037, Ance, Angiotensin converting enzyme, [Score=74.7, Expect=7e-15]} {Smed: dd_Smed_v6_13804_0_1, dd_Smed_v6_13804_0_1, [Score=51.2, Expect=2e-07]} {RNA1509_16360} {RNA1310_8949} {RNA815_4061}
49. MligTC455_41983 2249 46.86 Mlig455_014572

Neo: -

Age: -

Region-enriched R4: 2.314/0.00000
Region-enriched R3: 1.500/0.00235
Region-enriched R6: 1.362/0.01872
Region-enriched R5: 1.347/0.00318

BHMT 3.325 0.787 - - 0.804 0.964 0.770 Mlig455_014572 {REF} {Length: 2550} {Pfam: Homocysteine S-methyltransferase [PF02574.18, score=161.0]} {Human: ENSG00000145692, BHMT, betaine--homocysteine S-methyltransferase, [RH, Score=542, Expect=0.0]} {Mouse: ENSMUSG00000069324, Gm5096, predicted gene 5096, [RH, Score=545, Expect=0.0]; ENSMUSG00000074768, Bhmt, betaine-homocysteine methyltransferase, [RH, Score=545, Expect=0.0]} {Smed: dd_Smed_v6_873_0_1, dd_Smed_v6_873_0_1, [RH, Score=555, Expect=0.0]} {RNA1509_18954, RNA1509_57529} {RNA1310_18981.1, RNA1509_18954} {RNA1509_18954, RNA815_5900.2}
50. MligTC455_46260 1736 36.16 Mlig455_058605

Neo: -

Age: -

Region-enriched R3: 1.241/0.00018

Regeneration-upregulated R5: 1.429

Regeneration-enriched R5: 1.429

RETSAT 3.302 0.722 - - 0.912 0.705 0.963 Mlig455_058605 {REF} {Length: 5100} {Pfam: Sulfate permease family [PF00916.22, score=276.8]; STAS domain [PF01740.23, score=87.9]; Flavin containing amine oxidoreductase [PF01593.26, score=62.3]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=57.4]; FAD binding domain [PF00890.26, score=37.1]; FAD dependent oxidoreductase [PF12831.9, score=25.7]; FAD dependent oxidoreductase [PF01266.26, score=24.9]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=24.6]; STAS domain [PF13466.8, score=24.6]; Thi4 family [PF01946.19, score=19.7]; FAD binding domain [PF01494.21, score=19.3]} {Human: ENSG00000042445, RETSAT, retinol saturase, [Score=382, Expect=7e-118]} {Mouse: ENSMUSG00000056666, Retsat, retinol saturase (all trans retinol 13,14 reductase), [Score=401, Expect=3e-125]} {Dmel: FBgn0036770, Prestin, [Score=296, Expect=1e-85]} {Celegans: WBGene00013963, sulp-8, Anion transporter SULP-8a; Anion transporter SULP-8b; SULfate Permease family, [Score=308, Expect=2e-91]} {Smed: dd_Smed_v6_4250_0_2, dd_Smed_v6_4250_0_2, [Score=360, Expect=2e-108]} {RNA1509_1340} {RNA1310_6908.1} {RNA815_3307}
51. MligTC455_35633 4966 103.45 Mlig455_048471

Neo: -

Age: -

Region-enriched R4: 1.579/0.00682
Region-enriched R3: 1.493/0.00762

DHDH 3.297 0.739 0.760 - 0.958 0.840 - Mlig455_048471 {REF} {Length: 1491} {Pfam: Oxidoreductase family, NAD-binding Rossmann fold [PF01408.24, score=87.6]; Oxidoreductase family, C-terminal alpha/beta domain [PF02894.19, score=32.8]; Homoserine dehydrogenase, NAD binding domain [PF03447.18, score=19.9]} {Human: ENSG00000104808, DHDH, dihydrodiol dehydrogenase, [RH, Score=246, Expect=3e-79]} {Mouse: ENSMUSG00000011382, Dhdh, dihydrodiol dehydrogenase (dimeric), [RH, Score=248, Expect=4e-80]} {Dmel: FBgn0031418, CG3609, [RH, Score=231, Expect=1e-73]} {Smed: dd_Smed_v6_7643_0_1, dd_Smed_v6_7643_0_1, [RH, Score=213, Expect=9e-67]} {RNA1509_1049, RNA1509_4889, RNA1509_8979} {RNA1310_24236, RNA1509_1049, RNA1509_4889, RNA1509_8979} {RNA1509_1049, RNA1509_4889, RNA1509_8979, RNA815_11111.1}
52. MligTC455_40929 2670 55.63 Mlig455_015646

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.152

3.248 0.726 - 0.724 0.846 0.952 - Mlig455_015646 {REF} {Length: 2421} {TRANSSPLICED} {RNA1509_3650} {RNA1310_20423, RNA1509_3650} {RNA1509_3650, RNA815_3682}
53. MligTC455_50387 1074 22.38 Mlig455_018618

Neo: -

Age: logFC(26M/2M)=0.362

Region-enriched R4: 2.247/0.00001
Region-enriched R3: 1.935/0.00000

SLC8B1 2.847 - 0.947 - 0.959 0.941 - Mlig455_018618 {REF} {Length: 2020} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=96.0]} {Human: ENSG00000089060, SLC8B1, solute carrier family 8 member B1, [RH, Score=214, Expect=1e-62]} {Mouse: ENSMUSG00000032754, Slc8b1, solute carrier family 8 (sodium/lithium/calcium exchanger), member B1, [RH, Score=220, Expect=4e-65]} {Dmel: FBgn0033324, CG14744, [Score=126, Expect=8e-31]} {Celegans: WBGene00003572, ncx-7, Putative sodium/calcium exchanger 7, [RH, Score=168, Expect=3e-45]} {Smed: dd_Smed_v6_1009_1_1, dd_Smed_v6_1009_1_1, [RH, Score=254, Expect=2e-80]} {RNA1509_17694, RNA1509_27887, RNA1509_3073} {RNA1310_3165.1, RNA1509_17694, RNA1509_27887} {RNA1509_17694, RNA1509_27887, RNA815_1390}
54. MligTC455_20619 2288 47.67 Mlig455_055574

Neo: -

Age: Down-Down-Up

Region-enriched R3: 1.591/0.00258
Region-enriched R4: 1.303/0.03358

SLC24A5 2.779 0.930 0.870 - - 0.979 - Mlig455_055574 {REF} {Length: 3527} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=180.5]} {Human: ENSG00000188467, SLC24A5, solute carrier family 24 member 5, [RH, Score=378, Expect=2e-125]} {Mouse: ENSMUSG00000035183, Slc24a5, solute carrier family 24, member 5, [RH, Score=378, Expect=1e-125]} {Dmel: FBgn0265767, zyd, zydeco, [Score=359, Expect=2e-118]} {Celegans: WBGene00003569, ncx-4, Na/Ca eXchangers, [Score=304, Expect=4e-96]} {Smed: dd_Smed_v6_7121_0_1, dd_Smed_v6_7121_0_1, [RH, Score=469, Expect=1e-161]} {RNA1509_4708} {RNA1310_7971.1} {RNA815_7327}
55. MligTC455_38613 969 20.2 Mlig455_048005, Mlig455_063705

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.394

Region-enriched R3: 1.570/0.01256

POSTN 2.755 - 0.894 0.899 0.962 - -

Mlig455_048005 {REF} {Length: 629} {Pfam: Fasciclin domain [PF02469.24, score=22.3]} {Smed: dd_Smed_v6_1088_0_1, dd_Smed_v6_1088_0_1, [Score=52.0, Expect=7e-08]} {RNA1509_6801} {RNA1310_9258} {RNA815_5083}

Mlig455_063705 {REF} {Length: 2741} {Pfam: Fasciclin domain [PF02469.24, score=65.6]} {Human: ENSG00000133110, POSTN, periostin, [Score=67.0, Expect=9e-11]} {Mouse: ENSMUSG00000027750, Postn, periostin, osteoblast specific factor, [Score=63.5, Expect=7e-10]} {Smed: dd_Smed_v6_1088_0_1, dd_Smed_v6_1088_0_1, [Score=141, Expect=9e-35]} {RNA1509_45570, RNA1509_6801} {RNA1310_9258, RNA1509_45570, RNA1509_6801} {RNA1509_45570, RNA1509_6801, RNA815_5083}
56. MligTC455_36665 2410 50.21 Mlig455_028654

Neo: -

Age: logFC(26M/2M)=0.273

Region-enriched R3: 1.404/0.00674

PSAP 2.749 - 0.820 - 0.979 0.950 - Mlig455_028654 {REF} {Length: 3951} {Pfam: Saposin-like type B, region 1 [PF05184.17, score=340.1]; Saposin-like type B, region 2 [PF03489.19, score=316.5]; Homeodomain-like domain [PF13384.8, score=47.9]; Helix-turn-helix domain [PF13518.8, score=39.6]; Saposin A-type domain [PF02199.17, score=35.5]; Protein of unknown function (DUF2753) [PF10952.10, score=31.0]; Replication factor RFC1 C terminal domain [PF08519.14, score=24.2]; Winged helix-turn helix [PF13551.8, score=23.7]; HD domain [PF13023.8, score=21.9]; Delta endotoxin [PF18449.3, score=19.6]} {Human: ENSG00000197746, PSAP, prosaposin, [RH, Score=177, Expect=9e-47]} {Mouse: ENSMUSG00000004207, Psap, prosaposin, [RH, Score=154, Expect=6e-39]} {Dmel: FBgn0000416, Sap-r, Saposin-related, [RH, Score=245, Expect=3e-67]} {Smed: dd_Smed_v6_266_0_1, dd_Smed_v6_266_0_1, [Score=99.0, Expect=1e-22]} {RNA1509_1917} {RNA1310_9056} {RNA815_5033.1}
57. MligTC455_48360 594 12.37 Mlig455_034363

Neo: -

Age: -

Region-enriched R3: 2.361/0.00279
Region-enriched R4: 2.128/0.02443

2.742 - 0.840 - 0.938 0.964 - Mlig455_034363 {REF} {Length: 3889} {Pfam: Death domain [PF00531.24, score=30.1]} {Celegans: WBGene00002041, hum-8, Heavy chain, Unconventional Myosin, [Score=50.4, Expect=6e-06]} {Smed: dd_Smed_v6_13807_0_1, dd_Smed_v6_13807_0_1, [Score=105, Expect=3e-23]} {RNA1509_29690, RNA1509_59375} {RNA1310_5206.1, RNA1509_59375} {RNA1509_59375, RNA815_3494}
58. MligTC455_40293 973 20.27 Mlig455_003116

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.598

Region-enriched R4: 2.611/0.00000
Region-enriched R3: 1.603/0.00240
Region-enriched R5: 1.400/0.00374

VAV1 2.723 - 0.819 - 0.972 0.932 - Mlig455_003116 {REF} {Length: 5727} {Pfam: SH2 domain [PF00017.26, score=32.8]; RhoGEF domain [PF00621.22, score=31.4]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=27.4]} {Human: ENSG00000141968, VAV1, vav guanine nucleotide exchange factor 1, [Score=95.1, Expect=2e-19]} {Mouse: ENSMUSG00000034116, Vav1, vav 1 oncogene, [Score=92.0, Expect=1e-18]} {Dmel: FBgn0040068, Vav, Vav guanine nucleotide exchange factor, [Score=65.1, Expect=2e-10]} {Celegans: WBGene00006887, vav-1, [Score=65.5, Expect=9e-11]} {RNA1509_11835} {RNA1310_8757} {RNA815_2576}
59. MligTC455_40294 928 19.33 Mlig455_062769

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.415

Region-enriched R4: 2.693/0.00000
Region-enriched R3: 1.531/0.00694
Region-enriched R5: 1.366/0.00671

VAV1 2.707 - 0.813 - 0.964 0.930 - Mlig455_062769 {REF} {Length: 4319} {Pfam: SH2 domain [PF00017.26, score=34.9]; RhoGEF domain [PF00621.22, score=28.2]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=27.1]} {Human: ENSG00000141968, VAV1, vav guanine nucleotide exchange factor 1, [Score=93.6, Expect=5e-19]} {Mouse: ENSMUSG00000034116, Vav1, vav 1 oncogene, [Score=91.3, Expect=1e-18]} {Dmel: FBgn0040068, Vav, Vav guanine nucleotide exchange factor, [Score=61.2, Expect=2e-09]} {Celegans: WBGene00006887, vav-1, [Score=64.3, Expect=2e-10]} {RNA1509_11835} {RNA1310_8757} {RNA815_2576}
60. MligTC455_33836 2065 43.02 Mlig455_036757

Neo: -

Age: logFC(26M/2M)=-0.242

Region-enriched R3: 1.925/0.00000
Region-enriched R4: 1.200/0.01490
Region-enriched R5: 1.020/0.01114

CYP2J2 2.695 - 0.860 - - 0.971 0.864 Mlig455_036757 {REF} {Length: 1902} {Pfam: Cytochrome P450 [PF00067.24, score=314.8]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=252, Expect=2e-77]} {Mouse: ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=248, Expect=4e-76]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [Score=248, Expect=4e-76]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [Score=246, Expect=3e-75]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [Score=246, Expect=2e-75]; ENSMUSG00000066097, Cyp2j11, cytochrome P450, family 2, subfamily j, polypeptide 11, [Score=240, Expect=7e-73]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [Score=239, Expect=1e-72]; ENSMUSG00000082932, Cyp2j8, cytochrome P450, family 2, subfamily j, polypeptide 8, [Score=236, Expect=2e-71]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=208, Expect=1e-60]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [Score=226, Expect=7e-68]} {Smed: dd_Smed_v6_5344_0_2, dd_Smed_v6_5344_0_2, [RH, Score=260, Expect=8e-81]} {RNA1509_32471} {RNA1310_10330} {RNA815_3898.1}
61. MligTC455_23304 1206 25.12 Mlig455_036050

Neo: -

Age: Up-Down-Up

Region-enriched R3: 1.727/0.00398

CH25H 2.686 0.798 0.917 - 0.971 - - Mlig455_036050 {REF} {Length: 2059} {Pfam: Fatty acid hydroxylase superfamily [PF04116.15, score=77.6]} {Human: ENSG00000138135, CH25H, cholesterol 25-hydroxylase, [RH, Score=168, Expect=6e-50]} {Mouse: ENSMUSG00000050370, Ch25h, cholesterol 25-hydroxylase, [RH, Score=182, Expect=2e-55]} {Celegans: WBGene00018036, F35C8.5, Cholesterol 25-hydroxylase-like protein, [RH, Score=201, Expect=1e-62]} {RNA1509_10839, RNA1509_11085, RNA1509_2104, RNA1509_51868} {RNA1310_8947, RNA1509_10839, RNA1509_11085, RNA1509_51868} {RNA1509_10839, RNA1509_11085, RNA1509_51868, RNA815_835.1}
62. MligTC455_52058 1280 26.66 Mlig455_041271

Neo: -

Age: logFC(26M/2M)=0.755

Region-enriched R3: 1.713/0.01206

2.683 0.865 0.861 - 0.957 - - Mlig455_041271 {REF} {Length: 2151} {Celegans: WBGene00015469, C05D2.8, [RH, Score=207, Expect=2e-62]} {Smed: dd_Smed_v6_8821_0_1, dd_Smed_v6_8821_0_1, [Score=159, Expect=8e-45]} {RNA1509_15031, RNA1509_21776, RNA1509_33962, RNA1509_54125, RNA1509_56588} {RNA1310_13148, RNA1509_15031, RNA1509_21776, RNA1509_33962, RNA1509_54125, RNA1509_56588} {RNA1509_15031, RNA1509_21776, RNA1509_33962, RNA1509_54125, RNA1509_56588, RNA815_7949}
63. MligTC455_22998 1192 24.84 Mlig455_001873, Mlig455_001948

Neo: -

Age: logFC(26M/2M)=0.334

Region-enriched R4: 2.809/0.00024
Region-enriched R3: 2.226/0.00227
Region-enriched R5: 1.925/0.00474

GATA4 2.678 - 0.820 - 0.966 0.892 -

Mlig455_001873 {REF} {Length: 2384} {Pfam: GATA zinc finger [PF00320.29, score=98.7]; TFIIB zinc-binding [PF08271.14, score=29.6]; Putative GTPase activating protein for Arf [PF01412.20, score=28.6]} {Human: ENSG00000285109, GATA4, GATA binding protein 4, [Score=172, Expect=6e-47]; ENSG00000136574, GATA4, GATA binding protein 4, [Score=172, Expect=6e-47]; ENSG00000141448, GATA6, GATA binding protein 6, [Score=166, Expect=1e-43]} {Mouse: ENSMUSG00000021944, Gata4, GATA binding protein 4, [Score=173, Expect=1e-47]; ENSMUSG00000005836, Gata6, GATA binding protein 6, [Score=165, Expect=1e-43]; ENSMUSG00000015627, Gata5, GATA binding protein 5, [Score=165, Expect=5e-45]} {Dmel: FBgn0003117, pnr, pannier, [Score=170, Expect=3e-46]} {Celegans: WBGene00001249, elt-1, Transcription factor elt-1, [Score=147, Expect=1e-38]} {Smed: dd_Smed_v6_4075_0_2, dd_Smed_v6_4075_0_2, [RH, Score=143, Expect=2e-36]} {RNA1509_43294} {RNA1310_15255} {RNA815_30190}

Mlig455_001948 {REF} {Length: 2519} {Pfam: GATA zinc finger [PF00320.29, score=98.7]; TFIIB zinc-binding [PF08271.14, score=29.6]; Putative GTPase activating protein for Arf [PF01412.20, score=28.1]} {Human: ENSG00000136574, GATA4, GATA binding protein 4, [Score=172, Expect=6e-47]; ENSG00000285109, GATA4, GATA binding protein 4, [Score=172, Expect=6e-47]; ENSG00000141448, GATA6, GATA binding protein 6, [Score=166, Expect=1e-43]} {Mouse: ENSMUSG00000021944, Gata4, GATA binding protein 4, [Score=172, Expect=2e-47]; ENSMUSG00000005836, Gata6, GATA binding protein 6, [Score=165, Expect=1e-43]; ENSMUSG00000015627, Gata5, GATA binding protein 5, [Score=165, Expect=5e-45]} {Dmel: FBgn0003117, pnr, pannier, [Score=170, Expect=3e-46]} {Celegans: WBGene00001249, elt-1, Transcription factor elt-1, [Score=146, Expect=2e-38]} {Smed: dd_Smed_v6_4075_0_1, dd_Smed_v6_4075_0_1, [RH, Score=143, Expect=1e-36]} {RNA1509_43294} {RNA1310_15255, RNA1509_43294} {RNA1509_43294, RNA815_30190}
64. MligTC455_48920 539 11.22 Mlig455_004019, Mlig455_004101

Neo: -

Age: logFC(26M/2M)=0.521

Region-enriched R3: 4.806/0.00011

AMY1A 2.678 - 0.864 - 0.959 - 0.855

Mlig455_004019 {REF} {Length: 3692} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=47.0]} {Human: ENSG00000237763, AMY1A, amylase, alpha 1A (salivary), [Score=446, Expect=4e-152]; ENSG00000174876, AMY1B, amylase, alpha 1B (salivary), [Score=446, Expect=4e-152]; ENSG00000187733, AMY1C, amylase, alpha 1C (salivary), [Score=446, Expect=4e-152]; ENSG00000243480, AMY2A, amylase, alpha 2A (pancreatic), [Score=442, Expect=9e-151]; ENSG00000240038, AMY2B, amylase, alpha 2B (pancreatic), [Score=442, Expect=1e-150]} {Mouse: ENSMUSG00000074264, Amy1, amylase 1, salivary, [Score=441, Expect=4e-150]; ENSMUSG00000096770, Amy2a4, amylase 2a4, [Score=434, Expect=1e-147]; ENSMUSG00000093931, Amy2a3, amylase 2a3, [Score=434, Expect=1e-147]; ENSMUSG00000074268, Amy2a5, amylase 2a5, [Score=434, Expect=1e-147]; ENSMUSG00000096569, Amy2a2, amylase 2a2, [Score=434, Expect=1e-147]} {Dmel: FBgn0000078, Amy-d, Amylase distal, [Score=384, Expect=2e-128]} {Celegans: WBGene00008220, C50B6.7, Alpha-amylase, [Score=319, Expect=1e-100]} {RNA1509_8491} {RNA1310_6099.1} {RNA815_5046}

Mlig455_004101 {REF} {Length: 3934} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=47.0]} {Human: ENSG00000237763, AMY1A, amylase, alpha 1A (salivary), [Score=446, Expect=4e-152]; ENSG00000174876, AMY1B, amylase, alpha 1B (salivary), [Score=446, Expect=4e-152]; ENSG00000187733, AMY1C, amylase, alpha 1C (salivary), [Score=446, Expect=4e-152]; ENSG00000243480, AMY2A, amylase, alpha 2A (pancreatic), [Score=442, Expect=9e-151]; ENSG00000240038, AMY2B, amylase, alpha 2B (pancreatic), [Score=442, Expect=1e-150]} {Mouse: ENSMUSG00000074264, Amy1, amylase 1, salivary, [Score=441, Expect=4e-150]; ENSMUSG00000096770, Amy2a4, amylase 2a4, [Score=434, Expect=1e-147]; ENSMUSG00000093931, Amy2a3, amylase 2a3, [Score=434, Expect=1e-147]; ENSMUSG00000074268, Amy2a5, amylase 2a5, [Score=434, Expect=1e-147]; ENSMUSG00000096569, Amy2a2, amylase 2a2, [Score=434, Expect=1e-147]} {Dmel: FBgn0000078, Amy-d, Amylase distal, [Score=384, Expect=2e-128]} {Celegans: WBGene00008220, C50B6.7, Alpha-amylase, [Score=319, Expect=1e-100]} {RNA1509_38912, RNA1509_8491} {RNA1310_6099.1, RNA1509_38912} {RNA1509_38912, RNA815_5046}
65. MligTC455_48678 310 6.47 Mlig455_051170

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.654

Region-enriched R4: 4.319/0.00000
Region-enriched R5: 2.245/0.02276

2.677 - - 0.852 0.963 0.862 - Mlig455_051170 {REF} {Length: 954} {RNA1509_15660} {RNA1310_10726.1} {RNA815_29494}
66. MligTC455_46860 1191 24.81 Mlig455_018534

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=0.909

Region-enriched R3: 1.808/0.00423
Region-enriched R5: 1.239/0.03396

2.676 0.892 - - 0.955 0.829 - Mlig455_018534 {REF} {Length: 3025} {Pfam: Acyltransferase family [PF01757.24, score=80.7]; Nose resistant-to-fluoxetine protein, N-terminal domain [PF20146.1, score=39.1]} {Mouse: ENSMUSG00000046610, Oacyl, O-acyltransferase like, [Score=152, Expect=4e-38]} {Dmel: FBgn0031034, CG14205, [RH, Score=213, Expect=2e-58]} {Celegans: WBGene00003813, nrf-6, Nose resistant to fluoxetine protein 6, [Score=246, Expect=5e-70]} {RNA1509_3351, RNA1509_37199} {RNA1310_6513, RNA1509_3351, RNA1509_37199} {RNA1509_3351, RNA1509_37199, RNA815_2310}
67. MligTC455_18869 1346 28.04 Mlig455_067491

Neo: -

Age: -

Region-enriched R3: 1.933/0.00397
Region-enriched R4: 1.775/0.01938
Region-enriched R5: 1.440/0.02287

2.67 - - 0.726 0.987 0.957 - Mlig455_067491 {REF} {Length: 2320} {Pfam: NAD dependent epimerase/dehydratase family [PF01370.23, score=72.5]; GDP-mannose 4,6 dehydratase [PF16363.7, score=51.3]; 3-beta hydroxysteroid dehydrogenase/isomerase family [PF01073.21, score=46.4]; Male sterility protein [PF07993.14, score=42.2]; NAD(P)H-binding [PF13460.8, score=39.3]; Polysaccharide biosynthesis protein [PF02719.17, score=30.0]; KR domain [PF08659.12, score=29.5]; NmrA-like family [PF05368.15, score=28.0]; short chain dehydrogenase [PF00106.27, score=19.3]} {Celegans: WBGene00017429, F13D11.4, [RH, Score=213, Expect=4e-66]} {RNA1509_20033, RNA1509_5037} {RNA1310_19379, RNA1509_20033, RNA1509_5037} {RNA1509_20033, RNA1509_5037, RNA815_6182.1}
68. MligTC455_18868 1328 27.67 Mlig455_067483

Neo: -

Age: -

Region-enriched R3: 1.928/0.00492
Region-enriched R4: 1.837/0.01691
Region-enriched R5: 1.462/0.02245

2.663 - - 0.713 0.988 0.962 - Mlig455_067483 {REF} {Length: 405} {RNA1509_5037} {RNA1310_19379} {RNA815_6182.1}
69. MligTC455_38458 308 6.42 Mlig455_045398

Neo: -

Age: -

2.639 0.811 0.872 - 0.956 - - Mlig455_045398 {REF} {Length: 2465} {Pfam: CRT-like, chloroquine-resistance transporter-like [PF08627.12, score=67.0]} {RNA1509_38506, RNA1509_40463, RNA1509_45079, RNA1509_52251, RNA1509_58112} {RNA1310_11453, RNA1509_38506, RNA1509_40463, RNA1509_45079, RNA1509_52251, RNA1509_58112} {RNA1509_38506, RNA1509_40463, RNA1509_45079, RNA1509_52251, RNA1509_58112, RNA815_18529}
70. MligTC455_45334 2178 45.38 Mlig455_068883

Neo: -

Age: Down-Up-Down

Region-enriched R4: 1.795/0.00015
Region-enriched R3: 1.326/0.00189
Region-enriched R5: 1.022/0.01242

LIPA 2.628 - - 0.775 0.885 0.968 - Mlig455_068883 {REF} {Length: 2253} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=88.7]; Partial alpha/beta-hydrolase lipase region [PF04083.18, score=54.0]; Serine aminopeptidase, S33 [PF12146.10, score=47.6]; Alpha/beta hydrolase family [PF12697.9, score=30.4]} {Human: ENSG00000107798, LIPA, lipase A, lysosomal acid type, [RH, Score=323, Expect=2e-106]; ENSG00000182333, LIPF, lipase F, gastric type, [RH, Score=322, Expect=5e-106]; ENSG00000204021, LIPK, lipase family member K, [RH, Score=312, Expect=3e-102]} {Mouse: ENSMUSG00000024781, Lipa, lysosomal acid lipase A, [RH, Score=320, Expect=2e-105]; ENSMUSG00000024768, Lipf, lipase, gastric, [RH, Score=315, Expect=1e-103]; ENSMUSG00000056078, Lipm, lipase, family member M, [RH, Score=308, Expect=1e-100]} {Dmel: FBgn0032264, Lip4, Lipase 4, [RH, Score=265, Expect=1e-83]} {Celegans: WBGene00021963, lipl-6, LIPase Like, [RH, Score=295, Expect=9e-94]} {Smed: dd_Smed_v6_257_0_1, dd_Smed_v6_257_0_1, [RH, Score=360, Expect=2e-121]} {RNA1509_16913, RNA1509_19422, RNA1509_39468} {RNA1310_10300.2, RNA1509_16913, RNA1509_19422, RNA1509_39468} {RNA1509_16913, RNA1509_19422, RNA1509_39468, RNA815_4697}
71. MligTC455_17882 4410 91.87 Mlig455_017550, Mlig455_030854

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=-1.153

Region-enriched R6: 2.434/0.00204
Region-enriched R5: 1.911/0.00431
Region-enriched R3: 1.811/0.04295

Regeneration-upregulated TP: 4.451

Regeneration-enriched TP: 4.451

2.603 - - 0.865 0.952 0.786 -

Mlig455_017550 {REF} {Length: 2052} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=68.3]} {RNA1509_5435} {RNA1310_16003} {RNA815_8431}

Mlig455_030854 {REF} {Length: 1811} {RNA1509_41365, RNA1509_5435} {RNA1310_16003, RNA1509_41365} {RNA1509_41365, RNA815_8431}
72. MligTC455_50091 3389 70.6 Mlig455_041940

Neo: -

Age: logFC(26M/2M)=0.438

CAT 2.602 - - 0.878 0.971 0.753 - Mlig455_041940 {REF} {Length: 2013} {TRANSSPLICED} {Pfam: Catalase [PF00199.21, score=645.7]; Catalase-related immune-responsive [PF06628.14, score=80.3]} {Human: ENSG00000121691, CAT, catalase, [RH, Score=744, Expect=0.0]} {Mouse: ENSMUSG00000027187, Cat, catalase, [RH, Score=744, Expect=0.0]} {Dmel: FBgn0000261, Cat, Catalase, [RH, Score=704, Expect=0.0]} {Celegans: WBGene00000831, ctl-2, Peroxisomal catalase 1, [RH, Score=635, Expect=0.0]} {Smed: dd_Smed_v6_859_0_1, dd_Smed_v6_859_0_1, [RH, Score=640, Expect=0.0]} {RNA1509_2448, RNA1509_24848} {RNA1310_13356.1, RNA1509_2448, RNA1509_24848} {RNA1509_2448, RNA1509_24848, RNA815_4899.1}
73. MligTC455_32319 1579 32.9 Mlig455_065963

Neo: -

Age: -

Region-enriched R4: 1.893/0.00270

CTSA 2.601 - - - 0.865 0.957 0.779 Mlig455_065963 {REF} {Length: 1899} {TRANSSPLICED} {Pfam: Serine carboxypeptidase [PF00450.24, score=405.7]} {Human: ENSG00000064601, CTSA, cathepsin A, [RH, Score=417, Expect=1e-141]} {Mouse: ENSMUSG00000017760, Ctsa, cathepsin A, [RH, Score=425, Expect=1e-144]} {Dmel: FBgn0038738, CG4572, [Score=108, Expect=4e-25]} {Celegans: WBGene00019605, ctsa-1, Uncharacterized serine carboxypeptidase ctsa-1, [RH, Score=339, Expect=1e-111]} {Smed: dd_Smed_v6_785_0_1, dd_Smed_v6_785_0_1, [RH, Score=392, Expect=3e-132]} {RNA1509_366, RNA1509_39936} {RNA1310_10272.1, RNA1509_39936} {RNA1509_39936, RNA815_3612.1}
74. MligTC455_51597 1321 27.52 Mlig455_014868, Mlig455_014909, Mlig455_014993

Neo: -

Age: -

Region-enriched R3: 3.740/0.00000
Region-enriched R5: 2.963/0.00013
Region-enriched R6: 2.888/0.00494

SLC16A12 2.599 - - 0.813 0.972 0.814 -

Mlig455_014868 {REF} {Length: 5090} {Pfam: Major Facilitator Superfamily [PF07690.18, score=59.2]; Dynamin family [PF00350.25, score=28.1]; 50S ribosome-binding GTPase [PF01926.25, score=28.0]; Elongation factor Tu GTP binding domain [PF00009.29, score=25.7]; Protein kinase domain [PF00069.27, score=23.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=20.9]; FtsK/SpoIIIE family [PF01580.20, score=18.7]} {Human: ENSG00000152779, SLC16A12, solute carrier family 16 member 12, [Score=51.2, Expect=1e-05]} {Mouse: ENSMUSG00000045775, Slc16a5, solute carrier family 16 (monocarboxylic acid transporters), member 5, [Score=57.4, Expect=8e-08]} {Dmel: FBgn0033028, CG11665, [Score=63.5, Expect=1e-09]} {Smed: dd_Smed_v6_1284_0_1, dd_Smed_v6_1284_0_1, [RH, Score=514, Expect=4e-170]} {RNA1509_9414} {RNA1310_4109.2} {RNA815_1086}

Mlig455_014909 {REF} {Length: 3678} {Pfam: 50S ribosome-binding GTPase [PF01926.25, score=29.1]; Dynamin family [PF00350.25, score=28.2]; Protein kinase domain [PF00069.27, score=27.5]; Elongation factor Tu GTP binding domain [PF00009.29, score=25.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=23.9]; FtsK/SpoIIIE family [PF01580.20, score=18.9]} {Celegans: WBGene00013355, gck-3, Germinal center kinase 3, [Score=48.9, Expect=1e-05]} {Smed: dd_Smed_v6_7028_0_1, dd_Smed_v6_7028_0_1, [Score=60.1, Expect=5e-09]} {RNA1509_9414} {RNA1310_4109.2} {RNA815_1086}

Mlig455_014993 {REF} {Length: 4883} {Pfam: Major Facilitator Superfamily [PF07690.18, score=59.2]; Dynamin family [PF00350.25, score=28.1]; 50S ribosome-binding GTPase [PF01926.25, score=28.1]; Protein kinase domain [PF00069.27, score=25.6]; Elongation factor Tu GTP binding domain [PF00009.29, score=25.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=22.7]; FtsK/SpoIIIE family [PF01580.20, score=19.4]} {Human: ENSG00000152779, SLC16A12, solute carrier family 16 member 12, [Score=51.2, Expect=1e-05]} {Mouse: ENSMUSG00000045775, Slc16a5, solute carrier family 16 (monocarboxylic acid transporters), member 5, [Score=57.4, Expect=9e-08]} {Dmel: FBgn0033028, CG11665, [Score=63.5, Expect=9e-10]} {Smed: dd_Smed_v6_1284_0_1, dd_Smed_v6_1284_0_1, [RH, Score=515, Expect=2e-170]} {RNA1509_9414} {RNA1310_4109.2} {RNA815_1086}
75. MligTC455_34688 756 15.75 Mlig455_049905

Neo: -

Age: logFC(26M/2M)=0.524

Region-enriched R3: 2.234/0.00031
Region-enriched R4: 1.743/0.02090
Region-enriched R5: 1.276/0.04216

MGAM2 2.593 - 0.834 - 0.951 0.808 - Mlig455_049905 {REF} {Length: 4307} {Pfam: Glycosyl hydrolases family 31 [PF01055.28, score=486.1]; N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase [PF16863.7, score=39.1]; Galactose mutarotase-like [PF13802.8, score=25.5]} {Human: ENSG00000257743, MGAM2, maltase-glucoamylase 2 (putative), [Score=632, Expect=0.0]; ENSG00000278563, MGAM2, maltase-glucoamylase 2 (putative), [Score=632, Expect=0.0]; ENSG00000257335, MGAM, maltase-glucoamylase, [Score=626, Expect=0.0]; ENSG00000282607, MGAM, maltase-glucoamylase, [Score=617, Expect=0.0]; ENSG00000090402, SI, sucrase-isomaltase, [Score=605, Expect=0.0]} {Mouse: ENSMUSG00000068587, Mgam, maltase-glucoamylase, [Score=644, Expect=0.0]; ENSMUSG00000027790, Sis, sucrase isomaltase (alpha-glucosidase), [Score=631, Expect=0.0]} {Dmel: FBgn0027588, GCS2alpha, Glucosidase 2 alpha subunit, [Score=226, Expect=1e-61]} {Celegans: WBGene00017071, aagr-1, Acid Alpha Glucosidase Relate, [RH, Score=476, Expect=5e-153]} {Smed: dd_Smed_v6_1062_0_1, dd_Smed_v6_1062_0_1, [Score=530, Expect=2e-174]} {RNA1509_22266, RNA1509_2280, RNA1509_24970, RNA1509_29248, RNA1509_32202, RNA1509_33412} {RNA1310_4558.1, RNA1509_22266, RNA1509_2280, RNA1509_24970, RNA1509_29248, RNA1509_32202, RNA1509_33412} {RNA1509_22266, RNA1509_2280, RNA1509_24970, RNA1509_29248, RNA1509_32202, RNA1509_33412, RNA815_1348}
76. MligTC455_45587 1025 21.35 Mlig455_051369

Neo: -

Age: Down-Up-Down

Region-enriched R3: 2.196/0.00000

2.588 - - - 0.965 0.813 0.810 Mlig455_051369 {REF} {Length: 1638} {Pfam: Ecdysteroid kinase-like family [PF02958.22, score=98.4]; Protein of unknown function (DUF1679) [PF07914.13, score=50.1]; Phosphotransferase enzyme family [PF01636.25, score=28.8]} {Dmel: FBgn0051380, CG31380, [RH, Score=51.6, Expect=6e-07]} {RNA1509_16462, RNA1509_4592, RNA1509_49634} {RNA1310_8890, RNA1509_16462, RNA1509_4592, RNA1509_49634} {RNA1509_16462, RNA1509_4592, RNA1509_49634, RNA815_8347}
77. MligTC455_14741 176 3.67 Mlig455_011002

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=1.244

SMS 2.586 - 0.735 - 0.979 0.872 - Mlig455_011002 {REF} {Length: 1797} {Pfam: Spermine/spermidine synthase domain [PF01564.19, score=88.5]; Spermidine synthase tetramerisation domain [PF17284.4, score=27.5]} {Human: ENSG00000102172, SMS, spermine synthase, [RH, Score=159, Expect=6e-45]} {Mouse: ENSMUSG00000071708, Sms, spermine synthase, [RH, Score=159, Expect=4e-45]} {Dmel: FBgn0036272, CG4300, [RH, Score=168, Expect=1e-47]} {Smed: dd_Smed_v6_9035_0_1, dd_Smed_v6_9035_0_1, [Score=72.4, Expect=3e-14]} {RNA1509_38495} {RNA1310_22551} {RNA815_6564.2}
78. MligTC455_32761 994 20.72 Mlig455_031205

Neo: -

Age: Down-Down-Up

TTPAL 2.575 - - 0.838 0.963 - 0.774 Mlig455_031205 {REF} {Length: 1688} {Pfam: CRAL/TRIO domain [PF00650.22, score=52.1]} {Human: ENSG00000124120, TTPAL, alpha tocopherol transfer protein like, [Score=105, Expect=2e-25]; ENSG00000177182, CLVS1, clavesin 1, [Score=104, Expect=7e-25]; ENSG00000146352, CLVS2, clavesin 2, [Score=103, Expect=1e-24]} {Mouse: ENSMUSG00000017679, Ttpal, tocopherol (alpha) transfer protein-like, [Score=107, Expect=5e-26]; ENSMUSG00000019785, Clvs2, clavesin 2, [Score=103, Expect=4e-25]; ENSMUSG00000041216, Clvs1, clavesin 1, [Score=103, Expect=1e-24]} {Dmel: FBgn0036289, CG10657, [Score=114, Expect=5e-29]} {Smed: dd_Smed_v6_3680_0_1, dd_Smed_v6_3680_0_1, [Score=220, Expect=5e-69]} {RNA1509_52690} {RNA1310_22590.1} {RNA815_11166}
79. MligTC455_38362 1015 21.16 Mlig455_045508

Neo: -

Age: -

Region-enriched R4: 1.693/0.01745
Region-enriched R5: 1.163/0.02906

AADAC 2.575 0.735 - 0.856 0.984 - - Mlig455_045508 {REF} {Length: 2224} {Pfam: alpha/beta hydrolase fold [PF07859.15, score=113.1]; Carboxylesterase family [PF00135.30, score=19.9]} {Human: ENSG00000114771, AADAC, arylacetamide deacetylase, [Score=96.3, Expect=2e-21]; ENSG00000197953, AADACL2, arylacetamide deacetylase like 2, [Score=93.6, Expect=2e-20]; ENSG00000261846, AADACL2, arylacetamide deacetylase like 2, [Score=93.6, Expect=2e-20]} {Mouse: ENSMUSG00000090527, Gm5538, predicted gene 5538, [Score=102, Expect=1e-23]; ENSMUSG00000095522, Gm8298, predicted gene 8298, [Score=98.2, Expect=3e-22]} {Dmel: FBgn0034491, Hsl, Hormone-sensitive lipase, [Score=65.5, Expect=4e-11]} {Celegans: WBGene00012810, nceh-1, Neutral Cholesterol Ester Hydrolase homolog, [Score=98.2, Expect=2e-22]} {Smed: dd_Smed_v6_4674_0_1, dd_Smed_v6_4674_0_1, [Score=82.0, Expect=5e-17]} {RNA1509_14307} {RNA1310_15560.2} {RNA815_8354}
80. MligTC455_51882 911 18.99 Mlig455_036838, Mlig455_052977, Mlig455_053038

Neo: -

Age: logFC(26M/2M)=0.535

Region-enriched R4: 3.812/0.00000
Region-enriched R3: 1.761/0.01300
Region-enriched R5: 1.366/0.03532

ANK2 2.562 - 0.779 - 0.954 0.829 -

Mlig455_036838 {REF} {Length: 3082} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=92.5]; Ankyrin repeats (3 copies) [PF12796.9, score=88.5]; Ankyrin repeat [PF13606.8, score=66.9]; Ankyrin repeat [PF00023.32, score=61.3]; Ankyrin repeats (many copies) [PF13857.8, score=58.3]; Mab-21 protein [PF03281.16, score=29.1]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=84.7, Expect=6e-16]; ENSG00000170209, ANKK1, ankyrin repeat and kinase domain containing 1, [Score=82.8, Expect=2e-15]; ENSG00000137494, ANKRD42, ankyrin repeat domain 42, [Score=82.0, Expect=2e-15]; ENSG00000029534, ANK1, ankyrin 1, [Score=81.6, Expect=5e-15]; ENSG00000206560, ANKRD28, ankyrin repeat domain 28, [Score=80.5, Expect=8e-15]} {Mouse: ENSMUSG00000032257, Ankk1, ankyrin repeat and kinase domain containing 1, [Score=92.0, Expect=1e-18]; ENSMUSG00000014496, Ankrd28, ankyrin repeat domain 28, [Score=90.9, Expect=3e-18]} {Dmel: FBgn0031473, CG3104, [Score=87.4, Expect=3e-18]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=79.0, Expect=1e-14]} {Smed: dd_Smed_v6_10835_0_2, dd_Smed_v6_10835_0_2, [Score=85.1, Expect=1e-16]} {RNA1509_21275} {RNA1310_6086} {RNA815_930}

Mlig455_052977 {REF} {Length: 3059} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=91.0]; Ankyrin repeats (3 copies) [PF12796.9, score=88.1]; Ankyrin repeat [PF13606.8, score=65.6]; Ankyrin repeat [PF00023.32, score=63.0]; Ankyrin repeats (many copies) [PF13857.8, score=58.4]; Mab-21 protein [PF03281.16, score=29.1]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=85.1, Expect=5e-16]; ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=84.7, Expect=5e-16]; ENSG00000170209, ANKK1, ankyrin repeat and kinase domain containing 1, [Score=83.6, Expect=9e-16]; ENSG00000137494, ANKRD42, ankyrin repeat domain 42, [Score=82.4, Expect=1e-15]; ENSG00000135299, ANKRD6, ankyrin repeat domain 6, [Score=82.0, Expect=3e-15]; ENSG00000029534, ANK1, ankyrin 1, [Score=81.3, Expect=6e-15]} {Mouse: ENSMUSG00000032257, Ankk1, ankyrin repeat and kinase domain containing 1, [Score=92.8, Expect=8e-19]; ENSMUSG00000014496, Ankrd28, ankyrin repeat domain 28, [Score=89.7, Expect=9e-18]} {Dmel: FBgn0031473, CG3104, [Score=87.8, Expect=2e-18]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=80.9, Expect=4e-15]} {Smed: dd_Smed_v6_10835_0_2, dd_Smed_v6_10835_0_2, [Score=85.9, Expect=8e-17]} {RNA1509_21275} {RNA1310_6086} {RNA815_930}

Mlig455_053038 {REF} {Length: 3082} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=92.5]; Ankyrin repeats (3 copies) [PF12796.9, score=88.5]; Ankyrin repeat [PF13606.8, score=66.9]; Ankyrin repeat [PF00023.32, score=61.3]; Ankyrin repeats (many copies) [PF13857.8, score=58.3]; Mab-21 protein [PF03281.16, score=29.1]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=85.1, Expect=5e-16]; ENSG00000170209, ANKK1, ankyrin repeat and kinase domain containing 1, [Score=82.8, Expect=1e-15]; ENSG00000137494, ANKRD42, ankyrin repeat domain 42, [Score=82.0, Expect=2e-15]; ENSG00000029534, ANK1, ankyrin 1, [Score=81.6, Expect=5e-15]; ENSG00000206560, ANKRD28, ankyrin repeat domain 28, [Score=80.9, Expect=8e-15]} {Mouse: ENSMUSG00000032257, Ankk1, ankyrin repeat and kinase domain containing 1, [Score=92.4, Expect=1e-18]; ENSMUSG00000014496, Ankrd28, ankyrin repeat domain 28, [Score=91.3, Expect=3e-18]} {Dmel: FBgn0031473, CG3104, [Score=87.4, Expect=3e-18]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=79.7, Expect=9e-15]} {Smed: dd_Smed_v6_10835_0_2, dd_Smed_v6_10835_0_2, [Score=85.1, Expect=1e-16]} {RNA1509_21275} {RNA1310_6086, RNA1509_21275} {RNA1509_21275, RNA815_930}
81. MligTC455_34548 892 18.58 Mlig455_037149, Mlig455_052297

Neo: -

Age: Up-Down-Down

Region-enriched R3: 1.952/0.03060

2.56 - 0.823 - 0.953 0.784 -

Mlig455_037149 {REF} {Length: 10460} {TRANSSPLICED} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=31.2]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=55.8, Expect=5e-07]} {RNA1509_40938, RNA1509_4906} {RNA1310_88.1, RNA1509_40938} {RNA1509_40938, RNA815_214}

Mlig455_052297 {REF} {Length: 9432} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=36.3]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=52.0, Expect=7e-06]} {RNA1509_4906} {RNA1310_88.1} {RNA815_214}
82. MligTC455_46736 403 8.4 Mlig455_064968, Mlig455_066818

Neo: -

Age: -

Region-enriched R4: 2.255/0.01408

MAOA 2.556 0.738 - - 0.957 0.861 -

Mlig455_064968 {REF} {Length: 2244} {TRANSSPLICED} {Pfam: Flavin containing amine oxidoreductase [PF01593.26, score=191.6]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=43.1]; FAD dependent oxidoreductase [PF01266.26, score=30.3]; Thi4 family [PF01946.19, score=25.3]; Pyridine nucleotide-disulphide oxidoreductase [PF00070.29, score=24.5]; HI0933-like protein [PF03486.16, score=22.6]; FAD binding domain [PF00890.26, score=21.7]; FAD dependent oxidoreductase [PF12831.9, score=20.4]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=18.9]} {Human: ENSG00000189221, MAOA, monoamine oxidase A, [RH, Score=229, Expect=4e-68]} {Mouse: ENSMUSG00000025037, Maoa, monoamine oxidase A, [RH, Score=236, Expect=3e-71]} {Dmel: FBgn0039177, CG13611, [RH, Score=51.2, Expect=1e-06]} {Celegans: WBGene00000138, amx-2, AMine oXidase family, [Score=78.2, Expect=5e-15]} {Smed: dd_Smed_v6_7098_0_2, dd_Smed_v6_7098_0_2, [RH, Score=325, Expect=4e-106]} {RNA1509_46542} {RNA1310_20650} {RNA815_24826}

Mlig455_066818 {REF} {Length: 1937} {TRANSSPLICED} {Pfam: Flavin containing amine oxidoreductase [PF01593.26, score=191.0]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=43.2]; FAD dependent oxidoreductase [PF01266.26, score=30.7]; Thi4 family [PF01946.19, score=25.9]; Pyridine nucleotide-disulphide oxidoreductase [PF00070.29, score=24.4]; HI0933-like protein [PF03486.16, score=22.5]; FAD binding domain [PF00890.26, score=21.7]; FAD dependent oxidoreductase [PF12831.9, score=20.3]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=18.9]} {Human: ENSG00000189221, MAOA, monoamine oxidase A, [RH, Score=226, Expect=4e-67]} {Mouse: ENSMUSG00000025037, Maoa, monoamine oxidase A, [RH, Score=236, Expect=6e-71]} {Dmel: FBgn0039177, CG13611, [RH, Score=51.2, Expect=2e-06]} {Celegans: WBGene00000138, amx-2, AMine oXidase family, [Score=76.6, Expect=1e-14]} {Smed: dd_Smed_v6_6606_1_1, dd_Smed_v6_6606_1_1, [RH, Score=322, Expect=1e-104]} {RNA1509_46542, RNA1509_58749} {RNA1310_20650, RNA1509_46542, RNA1509_58749} {RNA1509_46542, RNA1509_58749, RNA815_24826}
83. MligTC455_45333 5039 104.98 Mlig455_024662, Mlig455_048643, Mlig455_068867

Neo: -

Age: Down-Up-Up

Region-enriched R4: 1.566/0.00006
Region-enriched R3: 1.419/0.00002

LIPA 2.55 0.704 - - 0.869 0.977 -

Mlig455_024662 {REF} {Length: 2228} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=85.7]; Partial alpha/beta-hydrolase lipase region [PF04083.18, score=52.3]; Serine aminopeptidase, S33 [PF12146.10, score=42.7]; Alpha/beta hydrolase family [PF12697.9, score=29.3]} {Human: ENSG00000107798, LIPA, lipase A, lysosomal acid type, [RH, Score=325, Expect=3e-100]; ENSG00000182333, LIPF, lipase F, gastric type, [RH, Score=324, Expect=2e-99]; ENSG00000204021, LIPK, lipase family member K, [RH, Score=313, Expect=8e-96]} {Mouse: ENSMUSG00000024781, Lipa, lysosomal acid lipase A, [RH, Score=322, Expect=3e-99]; ENSMUSG00000024768, Lipf, lipase, gastric, [RH, Score=317, Expect=3e-97]; ENSMUSG00000056078, Lipm, lipase, family member M, [RH, Score=309, Expect=3e-94]} {Dmel: FBgn0030052, CG12065, [RH, Score=276, Expect=6e-80]} {Celegans: WBGene00010062, lipl-1, Lipase, [RH, Score=295, Expect=2e-89]} {Smed: dd_Smed_v6_257_0_1, dd_Smed_v6_257_0_1, [RH, Score=361, Expect=6e-114]} {RNA1509_16913} {RNA1310_10300.2} {RNA815_4697}

Mlig455_048643 {REF} {Length: 2232} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=85.7]; Partial alpha/beta-hydrolase lipase region [PF04083.18, score=52.3]; Serine aminopeptidase, S33 [PF12146.10, score=42.7]; Alpha/beta hydrolase family [PF12697.9, score=29.3]} {Human: ENSG00000107798, LIPA, lipase A, lysosomal acid type, [RH, Score=325, Expect=3e-100]; ENSG00000182333, LIPF, lipase F, gastric type, [RH, Score=324, Expect=2e-99]; ENSG00000204021, LIPK, lipase family member K, [RH, Score=313, Expect=8e-96]} {Mouse: ENSMUSG00000024781, Lipa, lysosomal acid lipase A, [RH, Score=322, Expect=3e-99]; ENSMUSG00000024768, Lipf, lipase, gastric, [RH, Score=317, Expect=3e-97]; ENSMUSG00000056078, Lipm, lipase, family member M, [RH, Score=309, Expect=3e-94]} {Dmel: FBgn0030052, CG12065, [RH, Score=276, Expect=6e-80]} {Celegans: WBGene00010062, lipl-1, Lipase, [RH, Score=295, Expect=2e-89]} {Smed: dd_Smed_v6_257_0_1, dd_Smed_v6_257_0_1, [RH, Score=361, Expect=6e-114]} {RNA1509_16913} {RNA1310_10300.2} {RNA815_4697}

Mlig455_068867 {REF} {Length: 4154} {TRANSSPLICED} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=85.7]; Partial alpha/beta-hydrolase lipase region [PF04083.18, score=52.3]; Serine aminopeptidase, S33 [PF12146.10, score=42.7]; Alpha/beta hydrolase family [PF12697.9, score=29.3]} {Human: ENSG00000107798, LIPA, lipase A, lysosomal acid type, [RH, Score=325, Expect=3e-100]; ENSG00000182333, LIPF, lipase F, gastric type, [RH, Score=324, Expect=2e-99]; ENSG00000204021, LIPK, lipase family member K, [RH, Score=313, Expect=8e-96]} {Mouse: ENSMUSG00000024781, Lipa, lysosomal acid lipase A, [RH, Score=322, Expect=3e-99]; ENSMUSG00000024768, Lipf, lipase, gastric, [RH, Score=317, Expect=3e-97]; ENSMUSG00000056078, Lipm, lipase, family member M, [RH, Score=309, Expect=3e-94]} {Dmel: FBgn0030052, CG12065, [RH, Score=276, Expect=6e-80]} {Celegans: WBGene00010062, lipl-1, Lipase, [RH, Score=295, Expect=2e-89]} {Smed: dd_Smed_v6_257_0_1, dd_Smed_v6_257_0_1, [RH, Score=361, Expect=6e-114]} {RNA1509_16913} {RNA1310_10300.2} {RNA815_4697}
84. MligTC455_39600 674 14.05 Mlig455_012926, Mlig455_031140, Mlig455_032440

Neo: -

Age: -

Region-enriched R3: 3.870/0.00079

2.544 - 0.824 0.759 - 0.961 -

Mlig455_012926 {REF} {Length: 87} {NoTransDecoderORF} {RNA1509_3980} {RNA1310_20780.1} {RNA815_13375.1}

Mlig455_031140 {REF} {Length: 785} {NoTransDecoderORF} {RNA1509_20101} {RNA1310_14959.1} {RNA815_9852.1}

Mlig455_032440 {REF} {Length: 138} {NoTransDecoderORF} {RNA1509_3980} {RNA1310_20780.1} {RNA815_4111.1}
85. MligTC455_26168 821 17.11 Mlig455_019363

Neo: -

Age: logFC(26M/2M)=0.387

Region-enriched R5: 1.107/0.01127

2.537 0.725 - - - 0.971 0.841 Mlig455_019363 {REF} {Length: 4266} {TRANSSPLICED} {Pfam: Prokaryotic RING finger family 4 [PF14447.8, score=20.2]} {RNA1509_42908, RNA1509_8681} {RNA1310_8559, RNA1509_42908, RNA1509_8681} {RNA1509_42908, RNA1509_8681, RNA815_6586}
86. MligTC455_43368 6858 142.86 Mlig455_048986, Mlig455_049002

Neo: -

Age: Up-Down-Down

ACHE 2.531 0.716 0.855 - - - 0.960

Mlig455_048986 {REF} {Length: 14781} {Pfam: Carboxylesterase family [PF00135.30, score=2484.2]; alpha/beta hydrolase fold [PF07859.15, score=129.3]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=238, Expect=8e-66]} {Mouse: ENSMUSG00000058019, Ces5a, carboxylesterase 5A, [RH, Score=209, Expect=1e-56]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=189, Expect=3e-49]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=213, Expect=1e-57]} {Smed: dd_Smed_v6_10334_0_1, dd_Smed_v6_10334_0_1, [Score=202, Expect=8e-54]} {RNA1509_1156, RNA1509_14744, RNA1509_15426, RNA1509_18645, RNA1509_25748, RNA1509_38830, RNA1509_6237, RNA1509_82, RNA1509_8879} {RNA1310_83.1, RNA1509_1156, RNA1509_14744, RNA1509_15426, RNA1509_18645, RNA1509_25748, RNA1509_38830, RNA1509_6237, RNA1509_8879} {RNA1509_1156, RNA1509_14744, RNA1509_15426, RNA1509_18645, RNA1509_25748, RNA1509_38830, RNA1509_6237, RNA1509_8879, RNA815_40.1}

Mlig455_049002 {REF} {Length: 15214} {Pfam: Carboxylesterase family [PF00135.30, score=2695.8]; alpha/beta hydrolase fold [PF07859.15, score=131.9]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=238, Expect=1e-65]} {Mouse: ENSMUSG00000058019, Ces5a, carboxylesterase 5A, [RH, Score=211, Expect=7e-57]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=191, Expect=5e-50]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=207, Expect=1e-55]} {Smed: dd_Smed_v6_10334_0_1, dd_Smed_v6_10334_0_1, [Score=199, Expect=5e-53]} {RNA1509_82, RNA1509_8738} {RNA1310_83.1, RNA1509_8738} {RNA1509_8738, RNA815_40.1}
87. MligTC455_35660 846 17.62 Mlig455_000402

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=1.182

Region-enriched R3: 1.565/0.00201

AC099489.1 2.525 - 0.800 - 0.962 0.763 - Mlig455_000402 {REF} {Length: 12839} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=92.7]; Domain of unknown function (DUF1943) [PF09172.13, score=67.1]} {Human: ENSG00000188897, AC099489.1, vitellogenin, [Score=129, Expect=8e-29]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=96.3, Expect=2e-19]} {RNA1509_862} {RNA1310_65.1} {RNA815_55}
88. MligTC455_21905 681 14.18 Mlig455_016692, Mlig455_062345

Neo: Germline

Age: logFC(26M/2M)=0.410

Region-enriched R4: 2.760/0.00010

2.521 - - - 0.969 0.813 0.739

Mlig455_016692 {REF} {Length: 3207} {RNA1509_11497} {RNA1310_2097} {RNA815_6620}

Mlig455_062345 {REF} {Length: 877} {NoTransDecoderORF} {RNA1509_17998} {RNA1310_44069} {RNA815_10763.1}
89. MligTC455_18225 657 13.69 Mlig455_034956

Neo: -

Age: logFC(26M/2M)=0.287

2.5 - 0.732 - 0.968 0.800 - Mlig455_034956 {REF} {Length: 2635} {Pfam: Arrestin (or S-antigen), N-terminal domain [PF00339.31, score=45.3]; Arrestin (or S-antigen), C-terminal domain [PF02752.24, score=40.0]} {Dmel: FBgn0037518, CG2641, [Score=52.4, Expect=4e-07]} {Celegans: WBGene00012464, arrd-7, ARRestin Domain protein, [Score=54.7, Expect=5e-08]} {RNA1509_22116} {RNA1310_8444.1, RNA1509_22116} {RNA1509_22116, RNA815_2910}
90. MligTC455_48108 469 9.76 Mlig455_005110

Neo: -

Age: Down-Up-Up

SLC47A2 2.479 - 0.807 - 0.967 - 0.705 Mlig455_005110 {REF} {Length: 2550} {Pfam: MatE [PF01554.20, score=163.9]; Polysaccharide biosynthesis C-terminal domain [PF14667.8, score=29.8]} {Human: ENSG00000180638, SLC47A2, solute carrier family 47 member 2, [Score=294, Expect=7e-91]; ENSG00000142494, SLC47A1, solute carrier family 47 member 1, [Score=280, Expect=1e-85]} {Mouse: ENSMUSG00000010122, Slc47a1, solute carrier family 47, member 1, [Score=291, Expect=5e-90]; ENSMUSG00000069855, Slc47a2, solute carrier family 47, member 2, [Score=280, Expect=8e-86]} {Smed: dd_Smed_v6_11376_0_1, dd_Smed_v6_11376_0_1, [RH, Score=433, Expect=3e-145]} {RNA1509_37205} {RNA1310_8224.2, RNA1509_37205} {RNA1509_37205, RNA815_3210}
91. MligTC455_19366 2365 49.28 Mlig455_029830

Neo: -

Age: -

Region-enriched R3: 1.992/0.00057
Region-enriched R5: 1.418/0.01296

PANK3 2.471 - - 0.752 0.968 - 0.751 Mlig455_029830 {REF} {Length: 1495} {Pfam: Fumble [PF03630.16, score=108.9]} {Human: ENSG00000120137, PANK3, pantothenate kinase 3, [Score=57.0, Expect=2e-08]; ENSG00000152782, PANK1, pantothenate kinase 1, [Score=56.6, Expect=3e-08]; ENSG00000125779, PANK2, pantothenate kinase 2, [Score=55.1, Expect=5e-08]} {Mouse: ENSMUSG00000018846, Pank3, pantothenate kinase 3, [Score=56.6, Expect=2e-08]; ENSMUSG00000033610, Pank1, pantothenate kinase 1, [Score=56.2, Expect=2e-08]; ENSMUSG00000037514, Pank2, pantothenate kinase 2, [Score=55.8, Expect=4e-08]} {Dmel: FBgn0011205, fbl, fumble, [Score=55.1, Expect=5e-08]} {Smed: dd_Smed_v6_994_0_1, dd_Smed_v6_994_0_1, [RH, Score=227, Expect=2e-71]} {RNA1509_1801} {RNA1310_24657, RNA1509_1801} {RNA1509_1801, RNA815_10326}
92. MligTC455_50036 1353 28.19 Mlig455_063714

Neo: -

Age: logFC(26M/2M)=-0.294

Region-enriched R4: 1.826/0.00071
Region-enriched R3: 1.745/0.00078
Region-enriched R5: 1.202/0.01353

SPHK1 2.455 0.765 - 0.714 0.976 - - Mlig455_063714 {REF} {Length: 3647} {TRANSSPLICED} {Pfam: Diacylglycerol kinase catalytic domain [PF00781.26, score=81.8]} {Human: ENSG00000176170, SPHK1, sphingosine kinase 1, [Score=152, Expect=4e-43]} {Mouse: ENSMUSG00000061878, Sphk1, sphingosine kinase 1, [RH, Score=150, Expect=5e-44]; ENSMUSG00000057342, Sphk2, sphingosine kinase 2, [RH, Score=145, Expect=2e-39]} {Dmel: FBgn0030300, Sk1, Sphingosine kinase 1, [RH, Score=145, Expect=1e-39]} {Celegans: WBGene00007918, sphk-1, Sphingosine kinase 1, [Score=120, Expect=2e-31]} {Smed: dd_Smed_v6_5736_0_1, dd_Smed_v6_5736_0_1, [Score=127, Expect=3e-34]} {RNA1509_19326} {RNA1310_4471} {RNA815_1161}
93. MligTC455_44699 2074 43.2 Mlig455_048395

Neo: -

Age: logFC(26M/2M)=0.553

Region-enriched R3: 1.711/0.00637

SLC10A5 2.391 0.723 0.711 - 0.957 - - Mlig455_048395 {REF} {Length: 1771} {Pfam: Sodium Bile acid symporter family [PF01758.18, score=116.4]} {Human: ENSG00000253598, SLC10A5, solute carrier family 10 member 5, [RH, Score=130, Expect=9e-33]; ENSG00000100652, SLC10A1, solute carrier family 10 member 1, [RH, Score=125, Expect=2e-31]} {Mouse: ENSMUSG00000023073, Slc10a2, solute carrier family 10, member 2, [Score=129, Expect=4e-33]; ENSMUSG00000058921, Slc10a5, solute carrier family 10 (sodium/bile acid cotransporter family), member 5, [Score=125, Expect=6e-31]; ENSMUSG00000032806, Slc10a3, solute carrier family 10 (sodium/bile acid cotransporter family), member 3, [Score=124, Expect=9e-31]} {Dmel: FBgn0030756, CG9903, [Score=103, Expect=1e-23]} {Celegans: WBGene00044650, Y71G10AR.4, [RH, Score=206, Expect=4e-60]} {Smed: dd_Smed_v6_10199_0_1, dd_Smed_v6_10199_0_1, [RH, Score=295, Expect=3e-95]} {RNA1509_51285} {RNA1310_359.1} {RNA815_3102}
94. MligTC455_20618 1076 22.42 Mlig455_044808

Neo: -

Age: logFC(26M/2M)=-0.260

Region-enriched R4: 2.047/0.01278

SLC24A5 1.914 - - - 0.958 0.956 - Mlig455_044808 {REF} {Length: 2975} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=180.5]} {Human: ENSG00000188467, SLC24A5, solute carrier family 24 member 5, [RH, Score=378, Expect=2e-125]} {Mouse: ENSMUSG00000035183, Slc24a5, solute carrier family 24, member 5, [RH, Score=378, Expect=1e-125]} {Dmel: FBgn0265767, zyd, zydeco, [Score=359, Expect=2e-118]} {Celegans: WBGene00003569, ncx-4, Na/Ca eXchangers, [Score=304, Expect=4e-96]} {Smed: dd_Smed_v6_7121_0_1, dd_Smed_v6_7121_0_1, [RH, Score=469, Expect=1e-161]} {RNA1509_11724, RNA1509_31011, RNA1509_4708} {RNA1310_7971.1, RNA1509_11724, RNA1509_31011, RNA1509_4708} {RNA1509_11724, RNA1509_31011, RNA1509_4708, RNA815_7327}
95. MligTC455_35665 550 11.46 Mlig455_000411

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.492

AC099489.1 1.909 - - - 0.976 0.933 - Mlig455_000411 {REF} {Length: 12958} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=89.4]; Domain of unknown function (DUF1943) [PF09172.13, score=66.3]; von Willebrand factor type D domain [PF00094.27, score=25.5]} {Human: ENSG00000188897, AC099489.1, vitellogenin, [Score=122, Expect=1e-26]} {Dmel: FBgn0032136, Apoltp, Apolipoprotein lipid transfer particle, [Score=74.3, Expect=3e-12]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=93.6, Expect=3e-18]} {RNA1509_862} {RNA1310_65.2} {RNA815_55}
96. MligTC455_52631 525 10.95 Mlig455_005805, Mlig455_059403

Neo: -

Age: -

Region-enriched R6: 3.275/0.00143
Region-enriched R3: 3.065/0.00173
Region-enriched R4: 2.836/0.00562
Region-enriched R5: 2.683/0.00312

1.901 - - - 0.939 0.962 -

Mlig455_005805 {REF} {Length: 1711} {Pfam: Syntaxin 6, N-terminal [PF09177.13, score=36.6]} {RNA1509_51182} {RNA1310_21442.1} {RNA815_8498.1}

Mlig455_059403 {REF} {Length: 1696} {Pfam: Syntaxin 6, N-terminal [PF09177.13, score=46.1]} {RNA1509_37211} {RNA1310_27366, RNA1509_37211} {RNA1509_37211, RNA815_8498.2}
97. MligTC455_50388 1031 21.47 Mlig455_018603, Mlig455_018617

Neo: -

Age: Up-Down-Up

Region-enriched R3: 1.979/0.00000
Region-enriched R4: 1.829/0.00016

SLC8B1 1.898 - - - 0.955 0.943 -

Mlig455_018603 {REF} {Length: 3460} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=150.9]} {Human: ENSG00000089060, SLC8B1, solute carrier family 8 member B1, [RH, Score=215, Expect=5e-60]} {Mouse: ENSMUSG00000032754, Slc8b1, solute carrier family 8 (sodium/lithium/calcium exchanger), member B1, [RH, Score=222, Expect=1e-62]} {Dmel: FBgn0033324, CG14744, [Score=127, Expect=4e-30]} {Celegans: WBGene00003572, ncx-7, Putative sodium/calcium exchanger 7, [RH, Score=169, Expect=8e-44]} {Smed: dd_Smed_v6_9904_0_1, dd_Smed_v6_9904_0_1, [RH, Score=359, Expect=5e-110]} {RNA1509_3073} {RNA1310_3165.1, RNA1509_3073} {RNA1509_3073, RNA815_1390}

Mlig455_018617 {REF} {Length: 1059} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=47.3]} {Human: ENSG00000089060, SLC8B1, solute carrier family 8 member B1, [Score=97.1, Expect=4e-25]} {Mouse: ENSMUSG00000032754, Slc8b1, solute carrier family 8 (sodium/lithium/calcium exchanger), member B1, [Score=95.1, Expect=3e-23]} {Dmel: FBgn0033599, CG13223, [Score=60.5, Expect=3e-11]} {Celegans: WBGene00003572, ncx-7, Putative sodium/calcium exchanger 7, [Score=68.9, Expect=3e-14]} {Smed: dd_Smed_v6_20334_0_5, dd_Smed_v6_20334_0_5, [Score=114, Expect=6e-33]} {RNA1509_3073} {RNA1310_3165.1} {RNA815_1823}
98. MligTC455_16658 1547 32.23 Mlig455_056718, Mlig455_060300

Neo: -

Age: -

Region-enriched R3: 1.971/0.00155
Region-enriched R4: 1.653/0.02745

1.897 - - - - 0.957 0.940

Mlig455_056718 {REF} {Length: 1714} {Pfam: Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=44.7]} {RNA1509_50620, RNA1509_51103, RNA1509_8737} {RNA1310_8838, RNA1509_50620, RNA1509_51103} {RNA1509_50620, RNA1509_51103, RNA815_7244}

Mlig455_060300 {REF} {Length: 1815} {Pfam: Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=46.9]} {Smed: dd_Smed_v6_855_0_1, dd_Smed_v6_855_0_1, [Score=47.0, Expect=5e-06]} {RNA1509_8737} {RNA1310_8838, RNA1509_8737} {RNA1509_8737, RNA815_7244}
99. MligTC455_24698 664 13.84 Mlig455_002176

Neo: -

Age: Up-Down-Up

Region-enriched R3: 2.133/0.00000
Region-enriched R4: 1.095/0.04769

1.892 - - - 0.911 0.981 - Mlig455_002176 {REF} {Length: 1826} {TRANSSPLICED} {RNA1509_10156} {RNA1310_5607} {RNA815_1167}
100. MligTC455_35670 353 7.35 Mlig455_000478, Mlig455_000513

Neo: -

Age: logFC(26M/2M)=0.556

AC099489.1 1.873 - - - 0.979 0.894 -

Mlig455_000478 {REF} {Length: 11127} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=93.5]; Domain of unknown function (DUF1943) [PF09172.13, score=67.6]} {Human: ENSG00000188897, AC099489.1, vitellogenin, [Score=131, Expect=1e-29]} {Dmel: FBgn0087002, apolpp, apolipophorin, [Score=61.2, Expect=8e-09]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=91.7, Expect=3e-18]} {RNA1509_27087, RNA1509_28440} {RNA1310_65.2, RNA1509_28440} {RNA1509_28440, RNA815_55}

Mlig455_000513 {REF} {Length: 2538} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=41.7]} {Human: ENSG00000188897, AC099489.1, vitellogenin, [Score=68.6, Expect=2e-11]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=60.8, Expect=2e-09]} {RNA1509_27087} {RNA1310_65.2} {RNA815_55}

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