Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_19648 | 125 | 2.60 | Mlig455_034667, Mlig455_067587 | Neo: - Age: - Regeneration-downregulated BL: -7.490 Regeneration-depleted BL: -7.490 |
CHRNA7, CHRNA9 | Mlig455_034667 {REF} {Length: 1938} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=125.9]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=97.4]} {Human: ENSG00000174343, CHRNA9, cholinergic receptor nicotinic alpha 9 subunit, [Score=210, Expect=4e-62]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=207, Expect=9e-61]; ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=207, Expect=2e-61]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=205, Expect=4e-60]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=202, Expect=4e-59]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=200, Expect=1e-58]} {Mouse: ENSMUSG00000029205, Chrna9, cholinergic receptor, nicotinic, alpha polypeptide 9, [Score=213, Expect=2e-63]; ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=206, Expect=1e-60]} {Dmel: FBgn0000039, nAChRalpha2, nicotinic Acetylcholine Receptor alpha2, [Score=217, Expect=3e-64]} {Celegans: WBGene00000055, acr-16, Acetylcholine receptor subunit alpha-type acr-16, [Score=207, Expect=2e-61]} {Smed: dd_Smed_v6_23922_0_1, dd_Smed_v6_23922_0_1, [Score=202, Expect=1e-58]} {RNA1310_33414.1} {RNA815_34654} Mlig455_067587 {REF} {Length: 1709} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=158.1]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=96.7]} {Human: ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=230, Expect=8e-69]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=230, Expect=8e-69]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=228, Expect=3e-68]; ENSG00000174343, CHRNA9, cholinergic receptor nicotinic alpha 9 subunit, [Score=224, Expect=1e-66]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=230, Expect=3e-69]; ENSMUSG00000029205, Chrna9, cholinergic receptor, nicotinic, alpha polypeptide 9, [Score=227, Expect=3e-68]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=221, Expect=8e-66]} {Dmel: FBgn0000039, nAChRalpha2, nicotinic Acetylcholine Receptor alpha2, [Score=237, Expect=3e-71]} {Celegans: WBGene00000055, acr-16, Acetylcholine receptor subunit alpha-type acr-16, [Score=236, Expect=1e-71]} {Smed: dd_Smed_v6_23922_0_1, dd_Smed_v6_23922_0_1, [Score=232, Expect=2e-69]} {RNA1310_33414.2} {RNA815_34654} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | 2.146 | 2.108 | 0.34509 | 0.98870 | |
RegionR2 | -0.702 | 2.108 | 0.41644 | 0.80906 | |
RegionR3 | -0.813 | 2.108 | 0.27660 | 0.82038 | |
RegionR4 | -0.428 | 2.108 | 0.68630 | 0.97865 | |
RegionR5 | -2.095 | 2.108 | 0.01162 | 0.06443 | |
RegionR6 | 0.103 | 2.108 | 0.90596 | 1.00000 | |
RegionR7 | 0.422 | 2.108 | 0.64902 | 1.00000 | |
RegionR8 | 1.367 | 2.108 | 0.27915 | 0.90460 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -8.006 | 2.108 | 0.11428 | 0.83878 | |
RegenerationR2 | -1.003 | 2.108 | 0.14483 | 0.57621 | |
RegenerationR3 | -1.334 | 2.108 | 0.11181 | 0.52493 | |
RegenerationR4 | -2.222 | 2.108 | 0.02815 | 0.26953 | |
RegenerationR5 | 0.768 | 2.108 | 0.37518 | 0.78407 | |
RegenerationR6 | -1.979 | 2.108 | 0.01322 | 0.14187 | |
RegenerationBL | -7.49 | 2.108 | 0.00017 | 0.00650 | Specific for BL: -7.490 |
RegenerationTP | -1.861 | 2.108 | 0.09585 | 0.48514 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_19648 | 125 | 2.6 | Mlig455_034667, Mlig455_067587 | Neo: - Age: - Regeneration-downregulated BL: -7.490 Regeneration-depleted BL: -7.490 |
CHRNA7, CHRNA9 | 5 | 1.000 | - | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_034667 {REF} {Length: 1938} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=125.9]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=97.4]} {Human: ENSG00000174343, CHRNA9, cholinergic receptor nicotinic alpha 9 subunit, [Score=210, Expect=4e-62]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=207, Expect=9e-61]; ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=207, Expect=2e-61]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=205, Expect=4e-60]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=202, Expect=4e-59]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=200, Expect=1e-58]} {Mouse: ENSMUSG00000029205, Chrna9, cholinergic receptor, nicotinic, alpha polypeptide 9, [Score=213, Expect=2e-63]; ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=206, Expect=1e-60]} {Dmel: FBgn0000039, nAChRalpha2, nicotinic Acetylcholine Receptor alpha2, [Score=217, Expect=3e-64]} {Celegans: WBGene00000055, acr-16, Acetylcholine receptor subunit alpha-type acr-16, [Score=207, Expect=2e-61]} {Smed: dd_Smed_v6_23922_0_1, dd_Smed_v6_23922_0_1, [Score=202, Expect=1e-58]} {RNA1310_33414.1} {RNA815_34654} Mlig455_067587 {REF} {Length: 1709} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=158.1]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=96.7]} {Human: ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=230, Expect=8e-69]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=230, Expect=8e-69]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=228, Expect=3e-68]; ENSG00000174343, CHRNA9, cholinergic receptor nicotinic alpha 9 subunit, [Score=224, Expect=1e-66]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=230, Expect=3e-69]; ENSMUSG00000029205, Chrna9, cholinergic receptor, nicotinic, alpha polypeptide 9, [Score=227, Expect=3e-68]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=221, Expect=8e-66]} {Dmel: FBgn0000039, nAChRalpha2, nicotinic Acetylcholine Receptor alpha2, [Score=237, Expect=3e-71]} {Celegans: WBGene00000055, acr-16, Acetylcholine receptor subunit alpha-type acr-16, [Score=236, Expect=1e-71]} {Smed: dd_Smed_v6_23922_0_1, dd_Smed_v6_23922_0_1, [Score=232, Expect=2e-69]} {RNA1310_33414.2} {RNA815_34654} |
2. | MligTC455_05052 | 39 | 0.82 | Mlig455_060041 | Neo: - Age: - |
1.689 | - | - | - | 0.951 | 0.738 | - | Mlig455_060041 {REF} {Length: 2112} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=44.4]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=24.5]; Serpentine type 7TM GPCR chemoreceptor Srv [PF10323.11, score=18.7]} {Celegans: WBGene00015323, frpr-1, Probable G-protein coupled receptor frpr-1, [Score=53.9, Expect=8e-08]} {Smed: dd_Smed_v6_19397_0_1, dd_Smed_v6_19397_0_1, [Score=89.0, Expect=3e-19]} {RNA1310_29651} {RNA815_43873} | |
3. | MligTC455_03391 | 16 | 0.33 | Mlig455_033757 | Neo: - Age: - |
0.977 | - | - | 0.977 | - | - | - | Mlig455_033757 {REF} {Length: 1986} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=32.4]} {Smed: dd_Smed_v6_33870_0_1, dd_Smed_v6_33870_0_1, [RH, Score=102, Expect=1e-25]} {RNA1310_44705} {RNA815_38827} | |
4. | MligTC455_03392 | 16 | 0.33 | Mlig455_033765 | Neo: - Age: - |
0.977 | - | - | 0.977 | - | - | - | Mlig455_033765 {REF} {Length: 2002} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=31.8]} {Smed: dd_Smed_v6_33870_0_1, dd_Smed_v6_33870_0_1, [RH, Score=102, Expect=1e-25]} {RNA1310_44705} {RNA815_38827} | |
5. | MligTC455_27413 | 35 | 0.73 | Mlig455_061428 | Neo: - |
TLN1 | 0.972 | - | - | 0.972 | - | - | - | Mlig455_061428 {REF} {Length: 9019} {Pfam: I/LWEQ domain [PF01608.19, score=163.1]; Talin, middle domain [PF09141.12, score=97.8]; FERM central domain [PF00373.20, score=81.5]; Vinculin Binding Site [PF08913.12, score=27.2]} {Human: ENSG00000137076, TLN1, talin 1, [Score=1194, Expect=0.0]; ENSG00000171914, TLN2, talin 2, [Score=1147, Expect=0.0]} {Mouse: ENSMUSG00000028465, Tln1, talin 1, [Score=1186, Expect=0.0]; ENSMUSG00000052698, Tln2, talin 2, [Score=1142, Expect=0.0]} {Dmel: FBgn0260442, rhea, [Score=992, Expect=0.0]} {Celegans: WBGene00006771, tln-1, TaLiN; Talin, [Score=483, Expect=1e-137]} {Smed: dd_Smed_v6_876_0_1, dd_Smed_v6_876_0_1, [Score=769, Expect=0.0]} {RNA1509_38276} {RNA1310_1325} {RNA815_75.1} |
6. | MligTC455_16849 | 24 | 0.5 | Mlig455_061467 | Neo: - Age: - |
0.963 | - | - | - | 0.963 | - | - | Mlig455_061467 {REF} {Length: 2785} {Pfam: Cryptococcal mannosyltransferase 1 [PF11735.10, score=25.6]} {RNA1509_16212} {RNA1310_23116} {RNA815_8985.3} | |
7. | MligTC455_50178 | 50 | 1.04 | Mlig455_066991 | Neo: - Age: - Region-enriched R2: 5.585/0.00318 |
0.959 | - | - | - | 0.959 | - | - | Mlig455_066991 {REF} {Length: 982} {RNA1310_32436} | |
8. | MligTC455_12516 | 29 | 0.61 | Mlig455_023132 | Neo: - Age: - |
FCN2 | 0.958 | - | - | 0.958 | - | - | - | Mlig455_023132 {REF} {Length: 2517} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=61.0]; PAN domain [PF14295.8, score=24.6]} {Human: ENSG00000160339, FCN2, ficolin 2, [Score=75.9, Expect=9e-15]} {Mouse: ENSMUSG00000022309, Angpt1, angiopoietin 1, [Score=50.1, Expect=3e-06]; ENSMUSG00000027460, Angpt4, angiopoietin 4, [Score=49.7, Expect=4e-06]; ENSMUSG00000028553, Angptl3, angiopoietin-like 3, [Score=48.1, Expect=1e-05]; ENSMUSG00000002289, Angptl4, angiopoietin-like 4, [Score=47.8, Expect=1e-05]} {Dmel: FBgn0031804, CG9500, [Score=73.6, Expect=2e-14]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=49.7, Expect=2e-06]} {RNA1509_53291} {RNA1310_30694.1} {RNA815_10579.2} |
9. | MligTC455_47245 | 73 | 1.52 | Mlig455_027393 | Neo: - Age: - |
0.958 | - | - | - | - | - | 0.958 | Mlig455_027393 {REF} {Length: 1984} {Dmel: FBgn0034267, CG4984, [Score=52.4, Expect=1e-07]} {RNA1310_36758} {RNA815_27905} | |
10. | MligTC455_53081 | 86 | 1.8 | Mlig455_069206 | Neo: Int S/G2/M Age: - |
FANCD2 | 0.957 | - | - | 0.957 | - | - | - | Mlig455_069206 {REF} {Length: 5289} {TRANSSPLICED} {Pfam: Fanconi anaemia protein FancD2 nuclease [PF14631.8, score=216.2]} {Human: ENSG00000144554, FANCD2, FA complementation group D2, [RH, Score=131, Expect=5e-30]} {Mouse: ENSMUSG00000034023, Fancd2, Fanconi anemia, complementation group D2, [RH, Score=130, Expect=7e-30]} {Smed: dd_Smed_v6_12881_0_1, dd_Smed_v6_12881_0_1, [RH, Score=70.9, Expect=5e-12]} {RNA1509_14338} {RNA1310_1038} {RNA815_21338} |
11. | MligTC455_11836 | 23 | 0.47 | Mlig455_002196 | Neo: - Age: - |
0.953 | - | - | - | - | 0.953 | - | Mlig455_002196 {REF} {Length: 212} {NoTransDecoderORF} {RNA1509_39174} {RNA1310_96981.1} {RNA815_34070.1} | |
12. | MligTC455_26148 | 19 | 0.4 | Mlig455_009882 | Neo: - Age: - |
0.952 | - | - | - | - | 0.952 | - | Mlig455_009882 {REF} {Length: 2043} {Pfam: Methyltransferase domain [PF13383.8, score=62.4]; Methyltransferase FkbM domain [PF05050.14, score=29.9]} {Celegans: WBGene00012743, Y40H7A.3, [RH, Score=58.2, Expect=4e-09]} {Smed: dd_Smed_v6_3107_0_1, dd_Smed_v6_3107_0_1, [RH, Score=195, Expect=9e-58]} {RNA1310_27976} {RNA815_58780} | |
13. | MligTC455_45968 | 43 | 0.89 | Mlig455_058916 | Neo: - Age: - |
0.952 | - | - | - | - | 0.952 | - | Mlig455_058916 {REF} {Length: 3026} {Pfam: Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=53.9]; 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=29.4]} {Smed: dd_Smed_v6_27761_0_1, dd_Smed_v6_27761_0_1, [RH, Score=105, Expect=7e-25]} {RNA1310_38706} | |
14. | MligTC455_10716 | 109 | 2.26 | Mlig455_042739 | Neo: - Age: - Region-enriched R5: 2.906/0.00315 |
MAPK8IP3 | 0.951 | - | - | - | - | - | 0.951 | Mlig455_042739 {REF} {Length: 2108} {TRANSSPLICED} {Pfam: JNK_SAPK-associated protein-1 [PF09744.11, score=79.4]} {Human: ENSG00000138834, MAPK8IP3, mitogen-activated protein kinase 8 interacting protein 3, [Score=79.7, Expect=1e-15]} {Mouse: ENSMUSG00000024163, Mapk8ip3, mitogen-activated protein kinase 8 interacting protein 3, [Score=79.0, Expect=2e-15]} {Dmel: FBgn0024187, syd, sunday driver, [Score=78.6, Expect=1e-15]} {Celegans: WBGene00007860, rilp-1, RILP (Rab7-Interacting Lysosomal Protein) homolog, [Score=65.1, Expect=1e-11]} {Smed: dd_Smed_v6_3798_0_2, dd_Smed_v6_3798_0_2, [Score=70.5, Expect=3e-13]} {RNA1509_55505} {RNA1310_19989.2} {RNA815_12559.1} |
15. | MligTC455_25472 | 100 | 2.07 | Mlig455_040494 | Neo: - Age: Up-Up-Down |
RAPH1 | 0.951 | - | - | 0.951 | - | - | - | Mlig455_040494 {REF} {Length: 1705} {Pfam: PH domain [PF00169.31, score=40.6]} {Human: ENSG00000173166, RAPH1, Ras association (RalGDS/AF-6) and pleckstrin homology domains 1, [Score=107, Expect=2e-26]} {Mouse: ENSMUSG00000026014, Raph1, Ras association (RalGDS/AF-6) and pleckstrin homology domains 1, [Score=104, Expect=7e-26]} {Dmel: FBgn0261811, pico, [Score=88.2, Expect=4e-20]} {Celegans: WBGene00003243, mig-10, Abnormal cell migration protein 10, [Score=90.5, Expect=3e-21]} {Smed: dd_Smed_v6_3216_0_1, dd_Smed_v6_3216_0_1, [Score=120, Expect=9e-32]} {RNA1509_24403} {RNA1310_12419} {RNA815_13072} |