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Results for MligTC455_20153

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_20153 989 20.60 Mlig455_022272, Mlig455_048224

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.478

Region-enriched R2: 1.984/0.01966

CALM2

Mlig455_022272 {REF} {Length: 2203} {Pfam: EF hand [PF00036.34, score=117.8]; EF-hand domain pair [PF13499.8, score=101.8]; EF-hand domain [PF13405.8, score=94.4]; EF-hand domain pair [PF13833.8, score=78.3]; EF hand [PF13202.8, score=71.2]; EF-hand domain [PF14658.8, score=50.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=24.5]; Dockerin type I domain [PF00404.20, score=19.7]; EF-hand domain [PF17959.3, score=18.8]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=151, Expect=3e-46]; ENSG00000198668, CALM1, calmodulin 1, [Score=150, Expect=3e-46]; ENSG00000160014, CALM3, calmodulin 3, [Score=150, Expect=3e-46]; ENSG00000178363, CALML3, calmodulin like 3, [Score=144, Expect=5e-44]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=150, Expect=2e-46]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=150, Expect=2e-46]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=150, Expect=2e-46]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=149, Expect=4e-46]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=148, Expect=7e-46]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=148, Expect=5e-46]} {Smed: dd_Smed_v6_7222_0_1, dd_Smed_v6_7222_0_1, [RH, Score=158, Expect=5e-50]} {RNA1509_11855, RNA1509_40540, RNA1509_46868, RNA1509_55138, RNA1509_55739} {RNA1310_24547.1, RNA1509_11855, RNA1509_40540, RNA1509_46868, RNA1509_55138, RNA1509_55739} {RNA1509_11855, RNA1509_40540, RNA1509_46868, RNA1509_55138, RNA1509_55739, RNA815_19167}

Mlig455_048224 {REF} {Length: 2338} {Pfam: EF hand [PF00036.34, score=117.8]; EF-hand domain pair [PF13499.8, score=101.8]; EF-hand domain [PF13405.8, score=94.4]; EF-hand domain pair [PF13833.8, score=78.3]; EF hand [PF13202.8, score=71.2]; EF-hand domain [PF14658.8, score=50.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=24.5]; Dockerin type I domain [PF00404.20, score=19.7]; EF-hand domain [PF17959.3, score=18.8]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=151, Expect=3e-46]; ENSG00000198668, CALM1, calmodulin 1, [Score=150, Expect=3e-46]; ENSG00000160014, CALM3, calmodulin 3, [Score=150, Expect=3e-46]; ENSG00000178363, CALML3, calmodulin like 3, [Score=144, Expect=5e-44]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=150, Expect=2e-46]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=150, Expect=2e-46]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=150, Expect=2e-46]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=149, Expect=4e-46]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=148, Expect=7e-46]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=148, Expect=5e-46]} {Smed: dd_Smed_v6_7222_0_1, dd_Smed_v6_7222_0_1, [RH, Score=158, Expect=5e-50]} {RNA1509_11855, RNA1509_33416} {RNA1310_24547.1, RNA1509_33416} {RNA1509_33416, RNA815_19167}

Cumulative graph for MligTC455_20153

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.963 4.69 0.08176 0.62377
RegionR2 1.984 4.69 0.00086 0.01966
RegionR3 1.007 4.69 0.03739 0.33585
RegionR4 -0.222 4.69 0.70716 0.99374
RegionR5 -0.232 4.69 0.63628 0.98893
RegionR6 0.582 4.69 0.23446 0.81786
RegionR7 -0.768 4.69 0.17220 0.76239
RegionR8 -0.389 4.69 0.53565 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -6.045 4.69 0.19795 0.93767
RegenerationR2 -0.336 4.69 0.53618 0.88669
RegenerationR3 -0.333 4.69 0.58111 0.89943
RegenerationR4 -0.828 4.69 0.18278 0.62369
RegenerationR5 -0.949 4.69 0.11546 0.51130
RegenerationR6 -1.568 4.69 0.01477 0.14990
RegenerationBL -2.915 4.69 0.00170 0.03243
RegenerationTP -0.673 4.69 0.36399 0.80327


Genes with expression patterns similar to MligTC455_20153

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_20153 989 20.6 Mlig455_022272, Mlig455_048224

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.478

Region-enriched R2: 1.984/0.01966

CALM2 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_022272 {REF} {Length: 2203} {Pfam: EF hand [PF00036.34, score=117.8]; EF-hand domain pair [PF13499.8, score=101.8]; EF-hand domain [PF13405.8, score=94.4]; EF-hand domain pair [PF13833.8, score=78.3]; EF hand [PF13202.8, score=71.2]; EF-hand domain [PF14658.8, score=50.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=24.5]; Dockerin type I domain [PF00404.20, score=19.7]; EF-hand domain [PF17959.3, score=18.8]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=151, Expect=3e-46]; ENSG00000198668, CALM1, calmodulin 1, [Score=150, Expect=3e-46]; ENSG00000160014, CALM3, calmodulin 3, [Score=150, Expect=3e-46]; ENSG00000178363, CALML3, calmodulin like 3, [Score=144, Expect=5e-44]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=150, Expect=2e-46]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=150, Expect=2e-46]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=150, Expect=2e-46]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=149, Expect=4e-46]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=148, Expect=7e-46]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=148, Expect=5e-46]} {Smed: dd_Smed_v6_7222_0_1, dd_Smed_v6_7222_0_1, [RH, Score=158, Expect=5e-50]} {RNA1509_11855, RNA1509_40540, RNA1509_46868, RNA1509_55138, RNA1509_55739} {RNA1310_24547.1, RNA1509_11855, RNA1509_40540, RNA1509_46868, RNA1509_55138, RNA1509_55739} {RNA1509_11855, RNA1509_40540, RNA1509_46868, RNA1509_55138, RNA1509_55739, RNA815_19167}

Mlig455_048224 {REF} {Length: 2338} {Pfam: EF hand [PF00036.34, score=117.8]; EF-hand domain pair [PF13499.8, score=101.8]; EF-hand domain [PF13405.8, score=94.4]; EF-hand domain pair [PF13833.8, score=78.3]; EF hand [PF13202.8, score=71.2]; EF-hand domain [PF14658.8, score=50.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=24.5]; Dockerin type I domain [PF00404.20, score=19.7]; EF-hand domain [PF17959.3, score=18.8]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=151, Expect=3e-46]; ENSG00000198668, CALM1, calmodulin 1, [Score=150, Expect=3e-46]; ENSG00000160014, CALM3, calmodulin 3, [Score=150, Expect=3e-46]; ENSG00000178363, CALML3, calmodulin like 3, [Score=144, Expect=5e-44]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=150, Expect=2e-46]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=150, Expect=2e-46]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=150, Expect=2e-46]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=149, Expect=4e-46]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=148, Expect=7e-46]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=148, Expect=5e-46]} {Smed: dd_Smed_v6_7222_0_1, dd_Smed_v6_7222_0_1, [RH, Score=158, Expect=5e-50]} {RNA1509_11855, RNA1509_33416} {RNA1310_24547.1, RNA1509_33416} {RNA1509_33416, RNA815_19167}
2. MligTC455_11494 99 2.06 Mlig455_055605

Neo: -

Age: Down-Up-Down

HS3ST5 4.24 - 0.855 0.743 0.769 0.907 0.966 Mlig455_055605 {REF} {Length: 2196} {Pfam: Sulfotransferase domain [PF00685.29, score=91.7]; Sulfotransferase family [PF13469.8, score=45.8]} {Human: ENSG00000249853, HS3ST5, heparan sulfate-glucosamine 3-sulfotransferase 5, [RH, Score=256, Expect=1e-82]} {Mouse: ENSMUSG00000044499, Hs3st5, heparan sulfate (glucosamine) 3-O-sulfotransferase 5, [RH, Score=257, Expect=2e-83]} {Dmel: FBgn0031005, Hs3st-B, Heparan sulfate 3-O sulfotransferase-B, [Score=205, Expect=9e-63]} {Celegans: WBGene00044303, hst-3.2, Heparan SulphoTransferase, [Score=215, Expect=7e-68]} {Smed: dd_Smed_v6_81402_0_1, dd_Smed_v6_81402_0_1, [Score=123, Expect=7e-34]} {RNA1310_37118} {RNA815_58609}
3. MligTC455_32265 915 19.06 Mlig455_041418

Neo: -

Age: logFC(26M/2M)=-0.513

DCDC2 4.218 - 0.772 0.762 0.829 0.878 0.977 Mlig455_041418 {REF} {Length: 2999} {Pfam: Doublecortin [PF03607.19, score=82.8]; IQ calmodulin-binding motif [PF00612.29, score=68.9]} {Human: ENSG00000146038, DCDC2, doublecortin domain containing 2, [RH, Score=105, Expect=2e-23]} {Mouse: ENSMUSG00000035910, Dcdc2a, doublecortin domain containing 2a, [RH, Score=111, Expect=2e-25]} {Dmel: FBgn0013467, igl, igloo, [Score=50.8, Expect=1e-06]} {Smed: dd_Smed_v6_6464_0_1, dd_Smed_v6_6464_0_1, [Score=243, Expect=3e-70]} {RNA1509_53513, RNA1509_5661} {RNA1310_18305, RNA1509_53513} {RNA1509_53513, RNA815_9800.1}
4. MligTC455_47462 529 11.01 Mlig455_012033

Neo: -

Age: Down-Up-Down

CSMD3 4.196 - 0.730 0.789 0.810 0.901 0.966 Mlig455_012033 {REF} {Length: 3072} {Pfam: CUB domain [PF00431.22, score=95.8]; Wnt and FGF inhibitory regulator [PF13908.8, score=19.1]} {Human: ENSG00000164796, CSMD3, CUB and Sushi multiple domains 3, [Score=97.1, Expect=5e-20]; ENSG00000183117, CSMD1, CUB and Sushi multiple domains 1, [Score=93.2, Expect=9e-19]} {Mouse: ENSMUSG00000022311, Csmd3, CUB and Sushi multiple domains 3, [Score=95.9, Expect=8e-20]; ENSMUSG00000060924, Csmd1, CUB and Sushi multiple domains 1, [Score=94.7, Expect=2e-19]; ENSMUSG00000028804, Csmd2, CUB and Sushi multiple domains 2, [Score=92.4, Expect=9e-19]} {Dmel: FBgn0003719, tld, tolloid, [Score=58.5, Expect=2e-08]} {Celegans: WBGene00008294, clec-11, C-type LECtin, [Score=52.8, Expect=5e-07]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [Score=77.0, Expect=2e-14]} {RNA1509_35718, RNA1509_6830} {RNA1310_5183.1, RNA1509_35718} {RNA1509_35718, RNA815_5152}
5. MligTC455_52858 2196 45.76 Mlig455_015763, Mlig455_049488

Neo: -

Age: logFC(26M/2M)=-0.379

EFCAB10 4.092 - 0.754 0.767 0.776 0.819 0.976

Mlig455_015763 {REF} {Length: 734} {TRANSSPLICED} {Pfam: Family of unknown function (DUF5582) [PF17819.3, score=24.4]; Family of unknown function (DUF5586) [PF17824.3, score=23.9]} {Human: ENSG00000185055, EFCAB10, EF-hand calcium binding domain 10, [RH, Score=87.0, Expect=2e-22]} {Mouse: ENSMUSG00000020562, Efcab10, EF-hand calcium binding domain 10, [RH, Score=89.7, Expect=1e-23]} {Smed: dd_Smed_v6_6477_0_1, dd_Smed_v6_6477_0_1, [RH, Score=112, Expect=8e-33]} {RNA1509_21614} {RNA1310_54125.1} {RNA815_27872}

Mlig455_049488 {REF} {Length: 646} {TRANSSPLICED} {Pfam: Family of unknown function (DUF5582) [PF17819.3, score=24.4]; Family of unknown function (DUF5586) [PF17824.3, score=23.9]} {Human: ENSG00000185055, EFCAB10, EF-hand calcium binding domain 10, [RH, Score=87.0, Expect=2e-22]} {Mouse: ENSMUSG00000020562, Efcab10, EF-hand calcium binding domain 10, [RH, Score=89.7, Expect=1e-23]} {Smed: dd_Smed_v6_6477_0_1, dd_Smed_v6_6477_0_1, [RH, Score=112, Expect=8e-33]} {RNA1509_21614, RNA1509_38494} {RNA1310_54125.1, RNA1509_21614, RNA1509_38494} {RNA1509_21614, RNA1509_38494, RNA815_27872}
6. MligTC455_45891 7968 165.99 Mlig455_057102

Neo: -

Age: logFC(26M/2M)=-0.245

C1orf194 4.073 - 0.701 0.804 0.955 0.724 0.889 Mlig455_057102 {REF} {Length: 1201} {Pfam: Protein of unknown function (DUF3695) [PF12494.10, score=115.2]} {Human: ENSG00000179902, C1orf194, chromosome 1 open reading frame 194, [RH, Score=129, Expect=3e-38]} {Mouse: ENSMUSG00000027886, 1700013F07Rik, RIKEN cDNA 1700013F07 gene, [RH, Score=114, Expect=2e-32]} {Dmel: FBgn0032431, CG5435, [Score=66.2, Expect=9e-14]} {Smed: dd_Smed_v6_3833_0_1, dd_Smed_v6_3833_0_1, [RH, Score=181, Expect=3e-59]} {RNA1509_35267} {RNA1310_9088, RNA1509_35267} {RNA1509_35267, RNA815_9249}
7. MligTC455_31469 1076 22.43 Mlig455_002483

Neo: -

Age: Down-Up-Down

CCDC189 4.061 - 0.767 0.867 0.727 0.749 0.951 Mlig455_002483 {REF} {Length: 6604} {Pfam: Flagellar C1a complex subunit C1a-32 [PF14769.8, score=83.5]; PDZ domain [PF00595.26, score=76.3]; PDZ domain [PF17820.3, score=70.7]; PDZ domain [PF13180.8, score=43.3]; Tricorn protease PDZ domain [PF14685.8, score=23.4]} {Human: ENSG00000196118, CCDC189, coiled-coil domain containing 189, [Score=100, Expect=2e-22]} {Mouse: ENSMUSG00000057176, Ccdc189, coiled-coil domain containing 189, [Score=107, Expect=9e-25]} {Dmel: FBgn0024728, Slip1, [Score=61.6, Expect=3e-09]} {Celegans: WBGene00016846, C50F7.6, [Score=69.3, Expect=2e-12]} {Smed: dd_Smed_v6_12703_0_1, dd_Smed_v6_12703_0_1, [Score=117, Expect=6e-29]} {RNA1509_34490, RNA1509_53384} {RNA1310_23890, RNA1509_53384} {RNA1509_53384, RNA815_12270.1}
8. MligTC455_51307 298 6.2 Mlig455_032037

Neo: -

Age: -

DCTN1 3.477 - - 0.923 0.742 0.852 0.960 Mlig455_032037 {REF} {Length: 3293} {TRANSSPLICED} {Pfam: CAP-Gly domain [PF01302.27, score=63.8]; Macoilin family [PF09726.11, score=17.4]} {Human: ENSG00000204843, DCTN1, dynactin subunit 1, [Score=56.2, Expect=2e-07]; ENSG00000106665, CLIP2, CAP-Gly domain containing linker protein 2, [Score=56.2, Expect=2e-07]; ENSG00000197892, KIF13B, kinesin family member 13B, [Score=55.8, Expect=2e-07]} {Mouse: ENSMUSG00000031865, Dctn1, dynactin 1, [Score=57.0, Expect=9e-09]} {Dmel: FBgn0033055, Tbce, Tubulin-specific chaperone E, [Score=64.3, Expect=3e-10]} {Smed: dd_Smed_v6_12415_0_2, dd_Smed_v6_12415_0_2, [Score=97.1, Expect=9e-21]} {RNA1509_15825} {RNA1310_31448.1} {RNA815_3703.1}
9. MligTC455_43971 1049 21.85 Mlig455_014401

Neo: -

Age: logFC(26M/2M)=-0.330

NEK1 3.406 - 0.780 0.769 0.880 - 0.977 Mlig455_014401 {REF} {Length: 2439} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=118.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=68.0]; Kinase-like [PF14531.8, score=20.7]} {Human: ENSG00000137601, NEK1, NIMA related kinase 1, [Score=111, Expect=1e-24]} {Mouse: ENSMUSG00000049897, Stkld1, serine/threonine kinase-like domain containing 1, [RH, Score=142, Expect=3e-35]} {Dmel: FBgn0029970, Nek2, [Score=68.9, Expect=8e-12]} {Celegans: WBGene00021461, nekl-1, NEK (NEver in mitosis Kinase) Like, [Score=89.4, Expect=3e-18]} {Smed: dd_Smed_v6_10144_0_2, dd_Smed_v6_10144_0_2, [Score=100, Expect=7e-22]} {RNA1509_7618} {RNA1310_9007, RNA1509_7618} {RNA1509_7618, RNA815_6823}
10. MligTC455_16096 69 1.44 Mlig455_059809

Neo: -

Age: -

ANGPTL1 3.391 - - 0.790 0.805 0.833 0.963 Mlig455_059809 {REF} {Length: 1391} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=117.9]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=109, Expect=1e-26]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=106, Expect=2e-25]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=110, Expect=3e-27]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=105, Expect=2e-25]} {Dmel: FBgn0003326, sca, scabrous, [Score=91.3, Expect=3e-20]} {Celegans: WBGene00017013, ensh-1, [Score=61.2, Expect=1e-10]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=77.8, Expect=5e-16]} {RNA1509_28467} {RNA1310_47262} {RNA815_18070.1}
11. MligTC455_42132 837 17.43 Mlig455_012837

Neo: -

Age: logFC(26M/2M)=-0.387

EFCAB6 3.382 - 0.719 0.794 0.908 - 0.961 Mlig455_012837 {REF} {Length: 5469} {Pfam: EF-hand domain pair [PF13499.8, score=199.1]; EF-hand domain [PF08976.13, score=153.8]; EF-hand domain [PF13405.8, score=129.1]; EF hand [PF00036.34, score=112.1]; EF-hand domain pair [PF13833.8, score=77.4]; EF hand [PF13202.8, score=44.2]; Family of unknown function (DUF5580) [PF17743.3, score=35.6]} {Human: ENSG00000186976, EFCAB6, EF-hand calcium binding domain 6, [RH, Score=389, Expect=1e-111]} {Mouse: ENSMUSG00000022441, Efcab6, EF-hand calcium binding domain 6, [Score=373, Expect=4e-106]} {Smed: dd_Smed_v6_7065_0_1, dd_Smed_v6_7065_0_1, [RH, Score=743, Expect=0.0]} {RNA1509_39025} {RNA1310_902.1} {RNA815_763}
12. MligTC455_42172 67 1.39 Mlig455_066943

Neo: -

Age: Down-Up-Up

3.36 - - 0.796 0.839 0.756 0.969 Mlig455_066943 {REF} {Length: 2101} {Pfam: Innexin [PF00876.20, score=94.4]} {Celegans: WBGene00002133, inx-11, Innexin-11, [Score=87.8, Expect=9e-20]} {Smed: dd_Smed_v6_11501_0_1, dd_Smed_v6_11501_0_1, [Score=112, Expect=1e-28]} {RNA1509_10527} {RNA1310_14408} {RNA815_844.2}
13. MligTC455_48459 512 10.67 Mlig455_033033, Mlig455_044089

Neo: -

Age: logFC(26M/2M)=-0.316

Region-enriched R2: 2.708/0.00709

CSMD3 3.344 - 0.824 0.780 0.773 - 0.967

Mlig455_033033 {REF} {Length: 2936} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=194.1]} {Human: ENSG00000164796, CSMD3, CUB and Sushi multiple domains 3, [Score=161, Expect=2e-40]; ENSG00000183117, CSMD1, CUB and Sushi multiple domains 1, [Score=156, Expect=5e-39]; ENSG00000165124, SVEP1, sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1, [Score=155, Expect=1e-38]} {Mouse: ENSMUSG00000028369, Svep1, sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1, [Score=159, Expect=5e-40]; ENSMUSG00000060924, Csmd1, CUB and Sushi multiple domains 1, [Score=152, Expect=9e-38]} {Dmel: FBgn0032797, Hasp, Hig-anchoring scaffold protein, [Score=198, Expect=2e-53]} {Celegans: WBGene00002976, lev-9, [Score=123, Expect=3e-29]} {Smed: dd_Smed_v6_13071_0_1, dd_Smed_v6_13071_0_1, [RH, Score=296, Expect=2e-91]} {RNA1509_30688} {RNA1310_7890} {RNA815_3410.1}

Mlig455_044089 {REF} {Length: 2934} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=194.1]} {Human: ENSG00000164796, CSMD3, CUB and Sushi multiple domains 3, [Score=161, Expect=2e-40]; ENSG00000183117, CSMD1, CUB and Sushi multiple domains 1, [Score=156, Expect=5e-39]; ENSG00000165124, SVEP1, sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1, [Score=155, Expect=1e-38]} {Mouse: ENSMUSG00000028369, Svep1, sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1, [Score=159, Expect=5e-40]; ENSMUSG00000060924, Csmd1, CUB and Sushi multiple domains 1, [Score=152, Expect=9e-38]} {Dmel: FBgn0032797, Hasp, Hig-anchoring scaffold protein, [Score=198, Expect=2e-53]} {Celegans: WBGene00002976, lev-9, [Score=123, Expect=3e-29]} {Smed: dd_Smed_v6_13071_0_1, dd_Smed_v6_13071_0_1, [RH, Score=296, Expect=2e-91]} {RNA1509_30688} {RNA1310_7890, RNA1509_30688} {RNA1509_30688, RNA815_3410.1}
14. MligTC455_40989 801 16.68 Mlig455_016294

Neo: -

Age: logFC(26M/2M)=0.270

PKD2 3.338 0.725 - - 0.794 0.863 0.956 Mlig455_016294 {REF} {Length: 3179} {Pfam: Polycystin cation channel [PF08016.14, score=486.5]; Ion transport protein [PF00520.33, score=90.3]; EF hand [PF00036.34, score=23.7]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=718, Expect=0.0]; ENSG00000107593, PKD2L1, polycystin 2 like 1, transient receptor potential cation channel, [RH, Score=712, Expect=0.0]} {Mouse: ENSMUSG00000037578, Pkd2l1, polycystic kidney disease 2-like 1, [RH, Score=704, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [RH, Score=310, Expect=2e-91]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [RH, Score=370, Expect=7e-116]} {Smed: dd_Smed_v6_13327_0_1, dd_Smed_v6_13327_0_1, [RH, Score=743, Expect=0.0]} {RNA1509_14023, RNA1509_24240} {RNA1310_4836.1, RNA1509_14023, RNA1509_24240} {RNA1509_14023, RNA1509_24240, RNA815_4677}
15. MligTC455_35478 597 12.43 Mlig455_020720, Mlig455_020788

Neo: -

Age: logFC(26M/2M)=0.408

3.3 - 0.734 0.830 - 0.771 0.965

Mlig455_020720 {REF} {Length: 1135} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_13719} {RNA1310_25325} {RNA815_14669}

Mlig455_020788 {REF} {Length: 1139} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_13719} {RNA1310_25325} {RNA815_14669}
16. MligTC455_33791 1659 34.56 Mlig455_040695, Mlig455_064565

Neo: -

Age: logFC(26M/2M)=-0.516

NWD2 3.298 - - 0.730 0.780 0.808 0.980

Mlig455_040695 {REF} {Length: 5650} {Pfam: AAA ATPase domain [PF13191.8, score=37.7]; NACHT domain [PF05729.14, score=31.6]; ATPase domain predominantly from Archaea [PF01637.20, score=28.7]; AAA domain [PF13401.8, score=25.0]; P-loop containing dynein motor region [PF12775.9, score=22.6]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=145, Expect=4e-34]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [Score=145, Expect=3e-34]} {Dmel: FBgn0038397, CG10185, [Score=168, Expect=2e-41]} {Celegans: WBGene00020254, T05C3.2, [Score=202, Expect=7e-52]} {Smed: dd_Smed_v6_11466_0_1, dd_Smed_v6_11466_0_1, [RH, Score=722, Expect=0.0]} {RNA1509_2556} {RNA1310_841} {RNA815_245}

Mlig455_064565 {REF} {Length: 6818} {Pfam: AAA ATPase domain [PF13191.8, score=38.6]; NACHT domain [PF05729.14, score=32.5]; ATPase domain predominantly from Archaea [PF01637.20, score=28.1]; AAA domain [PF13401.8, score=24.5]; P-loop containing dynein motor region [PF12775.9, score=22.1]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=145, Expect=4e-34]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [Score=146, Expect=2e-34]} {Dmel: FBgn0038397, CG10185, [Score=171, Expect=4e-42]} {Celegans: WBGene00020254, T05C3.2, [Score=207, Expect=2e-53]} {Smed: dd_Smed_v6_11466_0_1, dd_Smed_v6_11466_0_1, [RH, Score=728, Expect=0.0]} {RNA1509_2556} {RNA1310_841, RNA1509_2556} {RNA1509_2556, RNA815_245}
17. MligTC455_22150 189 3.94 Mlig455_054947

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=2.071

XDH 3.274 - - 0.806 0.770 0.738 0.960 Mlig455_054947 {REF} {Length: 5481} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=346.4]; [2Fe-2S] binding domain [PF01799.22, score=95.7]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=91.5]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=51.5]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=47.3]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=25.1]} {Human: ENSG00000158125, XDH, xanthine dehydrogenase, [Score=476, Expect=9e-146]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=471, Expect=4e-144]; ENSMUSG00000079554, Aox2, aldehyde oxidase 2, [Score=457, Expect=7e-139]; ENSMUSG00000063558, Aox1, aldehyde oxidase 1, [Score=456, Expect=1e-138]; ENSMUSG00000038242, Aox4, aldehyde oxidase 4, [Score=449, Expect=5e-136]} {Dmel: FBgn0267408, AOX1, Aldehyde oxidase 1, [Score=640, Expect=0.0]} {Celegans: WBGene00010083, xhd-1, [Score=485, Expect=1e-149]} {RNA1509_325, RNA1509_38160} {RNA1310_1603.1, RNA1509_38160} {RNA1509_38160, RNA815_224.2}
18. MligTC455_16148 198 4.12 Mlig455_057689

Neo: -

Age: -

KLHDC8A 3.261 - 0.743 0.719 0.819 - 0.980 Mlig455_057689 {REF} {Length: 1806} {Pfam: Kelch motif [PF13964.8, score=56.9]; Kelch motif [PF01344.27, score=52.7]; Kelch motif [PF07646.17, score=37.5]; Galactose oxidase, central domain [PF13418.8, score=35.1]; Kelch motif [PF13854.8, score=27.6]} {Human: ENSG00000162873, KLHDC8A, kelch domain containing 8A, [Score=58.5, Expect=2e-09]} {Mouse: ENSMUSG00000042115, Klhdc8a, kelch domain containing 8A, [Score=63.9, Expect=1e-10]} {Smed: dd_Smed_v6_14507_0_1, dd_Smed_v6_14507_0_1, [RH, Score=209, Expect=4e-63]} {RNA1509_58319} {RNA1310_20213} {RNA815_8052}
19. MligTC455_32010 842 17.54 Mlig455_004590, Mlig455_064756

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.369

3.249 - 0.704 0.770 0.818 - 0.957

Mlig455_004590 {REF} {Length: 1488} {Smed: dd_Smed_v6_9116_0_1, dd_Smed_v6_9116_0_1, [RH, Score=55.8, Expect=1e-08]} {RNA1509_41382} {RNA1310_24662, RNA1509_41382} {RNA1509_41382, RNA815_11221}

Mlig455_064756 {REF} {Length: 1506} {Smed: dd_Smed_v6_9116_0_1, dd_Smed_v6_9116_0_1, [RH, Score=53.9, Expect=8e-08]} {RNA1509_23934} {RNA1310_24662, RNA1509_23934} {RNA1509_23934, RNA815_11221}
20. MligTC455_40658 152 3.17 Mlig455_064614

Neo: -

Age: -

CLIP2 3.245 - 0.725 0.752 0.801 - 0.967 Mlig455_064614 {REF} {Length: 2460} {Pfam: CAP-Gly domain [PF01302.27, score=60.7]} {Human: ENSG00000106665, CLIP2, CAP-Gly domain containing linker protein 2, [Score=61.6, Expect=2e-09]} {Mouse: ENSMUSG00000063146, Clip2, CAP-GLY domain containing linker protein 2, [Score=62.0, Expect=9e-10]} {Dmel: FBgn0036882, CG9279, [Score=55.1, Expect=9e-08]} {Smed: dd_Smed_v6_12985_0_1, dd_Smed_v6_12985_0_1, [Score=56.2, Expect=2e-08]} {RNA1310_20676} {RNA815_40746}
21. MligTC455_49883 494 10.3 Mlig455_048284

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.589

Region-enriched R2: 2.307/0.03081

ENO4 3.232 - - 0.705 0.745 0.829 0.953 Mlig455_048284 {REF} {Length: 2744} {Pfam: Enolase, C-terminal TIM barrel domain [PF00113.24, score=105.9]; Enolase, N-terminal domain [PF03952.18, score=35.3]} {Human: ENSG00000188316, ENO4, enolase 4, [RH, Score=218, Expect=9e-62]} {Mouse: ENSMUSG00000048029, Eno4, enolase 4, [RH, Score=204, Expect=3e-57]} {Dmel: FBgn0000579, Eno, Enolase, [Score=86.3, Expect=1e-17]} {Celegans: WBGene00011884, enol-1, Enolase, [Score=96.7, Expect=4e-21]} {Smed: dd_Smed_v6_12607_0_1, dd_Smed_v6_12607_0_1, [RH, Score=185, Expect=5e-51]} {RNA1509_28987, RNA1509_47129} {RNA1310_7158.1, RNA1509_47129} {RNA1509_47129, RNA815_8709}
22. MligTC455_43961 30 0.62 Mlig455_027626

Neo: -

Age: -

3.193 - - 0.762 0.770 0.702 0.959 Mlig455_027626 {REF} {Length: 602} {Pfam: PAN domain [PF00024.28, score=26.5]; PAN domain [PF14295.8, score=21.8]} {RNA1310_35396.1} {RNA815_23500}
23. MligTC455_20961 1780 37.08 Mlig455_031266

Neo: -

Age: logFC(26M/2M)=-0.283

Region-enriched R2: 1.483/0.00269

WDR63 3.187 0.707 0.783 - 0.735 - 0.962 Mlig455_031266 {REF} {Length: 3089} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=24.4]} {Human: ENSG00000162643, WDR63, WD repeat domain 63, [RH, Score=594, Expect=0.0]} {Mouse: ENSMUSG00000043020, Wdr63, WD repeat domain 63, [RH, Score=573, Expect=0.0]} {Dmel: FBgn0035799, CG14838, [RH, Score=176, Expect=1e-44]} {Smed: dd_Smed_v6_9187_0_1, dd_Smed_v6_9187_0_1, [RH, Score=736, Expect=0.0]} {RNA1509_2565} {RNA1310_5160, RNA1509_2565} {RNA1509_2565, RNA815_1888}
24. MligTC455_48766 985 20.53 Mlig455_020052, Mlig455_022298

Neo: -

Age: logFC(26M/2M)=-0.287

ODF3 3.178 - 0.767 - 0.735 0.709 0.967

Mlig455_020052 {REF} {Length: 1742} {TRANSSPLICED} {Pfam: Sperm-tail PG-rich repeat [PF07004.14, score=82.0]} {Human: ENSG00000177947, ODF3, outer dense fiber of sperm tails 3, [RH, Score=188, Expect=6e-59]} {Mouse: ENSMUSG00000025482, Odf3, outer dense fiber of sperm tails 3, [RH, Score=187, Expect=1e-58]} {Dmel: FBgn0032010, CG8086, [RH, Score=119, Expect=2e-32]} {Smed: dd_Smed_v6_2658_0_1, dd_Smed_v6_2658_0_1, [Score=304, Expect=4e-105]} {RNA1509_28289, RNA1509_56680} {RNA1310_15149, RNA1509_56680} {RNA1509_56680, RNA815_9422}

Mlig455_022298 {REF} {Length: 2031} {TRANSSPLICED} {Pfam: Sperm-tail PG-rich repeat [PF07004.14, score=82.0]} {Human: ENSG00000177947, ODF3, outer dense fiber of sperm tails 3, [RH, Score=188, Expect=6e-59]} {Mouse: ENSMUSG00000025482, Odf3, outer dense fiber of sperm tails 3, [RH, Score=187, Expect=1e-58]} {Dmel: FBgn0032010, CG8086, [RH, Score=119, Expect=2e-32]} {Smed: dd_Smed_v6_2658_0_1, dd_Smed_v6_2658_0_1, [Score=304, Expect=4e-105]} {RNA1509_28289, RNA1509_54276} {RNA1310_15149, RNA1509_28289, RNA1509_54276} {RNA1509_28289, RNA1509_54276, RNA815_9422}
25. MligTC455_30611 129 2.68 Mlig455_031173

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.392

Region-enriched R8: 4.530/0.01124

ITPR1 3.089 - - 0.707 0.707 0.721 0.954 Mlig455_031173 {REF} {Length: 9349} {Pfam: RIH domain [PF01365.23, score=93.2]; Inositol 1,4,5-trisphosphate/ryanodine receptor [PF08709.13, score=76.6]; RyR and IP3R Homology associated [PF08454.13, score=72.8]; MIR domain [PF02815.21, score=44.1]; Ion transport protein [PF00520.33, score=31.9]} {Human: ENSG00000150995, ITPR1, inositol 1,4,5-trisphosphate receptor type 1, [Score=239, Expect=4e-62]; ENSG00000123104, ITPR2, inositol 1,4,5-trisphosphate receptor type 2, [Score=229, Expect=2e-59]} {Mouse: ENSMUSG00000042644, Itpr3, inositol 1,4,5-triphosphate receptor 3, [Score=241, Expect=7e-63]} {Dmel: FBgn0010051, Itp-r83A, Inositol 1,4,5,-tris-phosphate receptor, [Score=202, Expect=3e-51]} {Celegans: WBGene00002173, itr-1, Inositol 1,4,5-trisphosphate receptor itr-1, [Score=174, Expect=7e-43]} {Smed: dd_Smed_v6_3814_1_1, dd_Smed_v6_3814_1_1, [Score=1868, Expect=0.0]} {RNA1509_5518} {RNA1310_129.1} {RNA815_62.1}
26. MligTC455_16370 2203 45.9 Mlig455_030628, Mlig455_031013

Neo: -

Age: logFC(26M/2M)=-0.323

ARMC3 2.694 - - 0.862 0.872 - 0.960

Mlig455_030628 {REF} {Length: 2931} {TRANSSPLICED} {Pfam: Ethylene-responsive protein kinase Le-CTR1 [PF14381.8, score=96.4]; Armadillo/beta-catenin-like repeat [PF00514.25, score=81.7]; HEAT repeats [PF13646.8, score=63.8]; HEAT-like repeat [PF13513.8, score=49.3]; V-ATPase subunit H [PF11698.10, score=49.2]; HEAT repeat [PF02985.24, score=38.5]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=29.0]} {Human: ENSG00000165309, ARMC3, armadillo repeat containing 3, [Score=496, Expect=2e-162]} {Mouse: ENSMUSG00000037683, Armc3, armadillo repeat containing 3, [Score=471, Expect=7e-153]} {Dmel: FBgn0033794, CG13326, [RH, Score=62.8, Expect=1e-09]} {Smed: dd_Smed_v6_9679_0_1, dd_Smed_v6_9679_0_1, [Score=665, Expect=0.0]} {RNA1509_7762} {RNA1310_5967} {RNA815_1775.1}

Mlig455_031013 {REF} {Length: 2952} {TRANSSPLICED} {Pfam: Ethylene-responsive protein kinase Le-CTR1 [PF14381.8, score=96.8]; Armadillo/beta-catenin-like repeat [PF00514.25, score=80.8]; HEAT repeats [PF13646.8, score=63.8]; V-ATPase subunit H [PF11698.10, score=50.9]; HEAT-like repeat [PF13513.8, score=48.4]; HEAT repeat [PF02985.24, score=40.7]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=31.6]; Required for nuclear transport of RNA pol II C-terminus 1 [PF10363.11, score=18.7]} {Human: ENSG00000165309, ARMC3, armadillo repeat containing 3, [Score=474, Expect=3e-154]} {Mouse: ENSMUSG00000037683, Armc3, armadillo repeat containing 3, [Score=335, Expect=1e-101]} {Dmel: FBgn0033794, CG13326, [RH, Score=62.8, Expect=1e-09]} {Smed: dd_Smed_v6_9679_0_1, dd_Smed_v6_9679_0_1, [Score=643, Expect=0.0]} {RNA1509_7762} {RNA1310_5967} {RNA815_1775.1}
27. MligTC455_37255 1581 32.94 Mlig455_048614

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.529

GAS8 2.674 - - - 0.840 0.867 0.967 Mlig455_048614 {REF} {Length: 2237} {Pfam: Growth-arrest specific micro-tubule binding [PF13851.8, score=274.9]} {Human: ENSG00000141013, GAS8, growth arrest specific 8, [RH, Score=623, Expect=0.0]} {Mouse: ENSMUSG00000040220, Gas8, growth arrest specific 8, [RH, Score=617, Expect=0.0]} {Dmel: FBgn0029667, Gas8, Growth arrest specific protein 8, [RH, Score=358, Expect=1e-119]} {Smed: dd_Smed_v6_2848_0_1, dd_Smed_v6_2848_0_1, [RH, Score=644, Expect=0.0]} {RNA1509_41557, RNA1509_4695} {RNA1310_10753.1, RNA1509_41557} {RNA1509_41557, RNA815_4143}
28. MligTC455_38402 477 9.94 Mlig455_049227

Neo: -

Age: -

2.66 - 0.786 - 0.902 - 0.972 Mlig455_049227 {REF} {Length: 2450} {TRANSSPLICED} {RNA1509_27392, RNA1509_28215} {RNA1310_19016, RNA1509_27392, RNA1509_28215} {RNA1509_27392, RNA1509_28215, RNA815_11860}
29. MligTC455_19225 26 0.54 Mlig455_018507

Neo: -

Age: -

SCNN1B 2.646 - - - 0.924 0.950 0.772 Mlig455_018507 {REF} {Length: 2590} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=142.8]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=59.3, Expect=1e-08]} {Celegans: WBGene00012116, del-4, DEgenerin Like, [Score=60.8, Expect=1e-09]} {Smed: dd_Smed_v6_17245_0_1, dd_Smed_v6_17245_0_1, [Score=49.3, Expect=5e-06]} {RNA1509_52685} {RNA1310_32081} {RNA815_49764}
30. MligTC455_39145 860 17.92 Mlig455_045710

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.035/0.04635

2.642 - 0.754 - 0.919 - 0.969 Mlig455_045710 {REF} {Length: 2657} {Pfam: Family of unknown function (DUF5580) [PF17743.3, score=80.4]} {Smed: dd_Smed_v6_9326_0_1, dd_Smed_v6_9326_0_1, [RH, Score=180, Expect=1e-49]} {RNA1509_11160, RNA1509_32698} {RNA1310_8387, RNA1509_11160, RNA1509_32698} {RNA1509_11160, RNA1509_32698, RNA815_15696.1}
31. MligTC455_41055 112 2.34 Mlig455_044574

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.659

Region-enriched R2: 6.247/0.00008

2.627 - - 0.820 0.841 - 0.966 Mlig455_044574 {REF} {Length: 1203} {Smed: dd_Smed_v6_9736_0_1, dd_Smed_v6_9736_0_1, [Score=86.7, Expect=1e-20]} {RNA1509_58567} {RNA1310_87689} {RNA815_53353}
32. MligTC455_14181 1196 24.91 Mlig455_043723, Mlig455_047435

Neo: -

Age: logFC(26M/2M)=-0.334

2.625 - - - 0.963 0.707 0.955

Mlig455_043723 {REF} {Length: 1333} {RNA1509_15671} {RNA1310_24777} {RNA815_10623}

Mlig455_047435 {REF} {Length: 1668} {RNA1509_15671} {RNA1310_24777, RNA1509_15671} {RNA1509_15671, RNA815_10623}
33. MligTC455_41324 401 8.35 Mlig455_024997

Neo: -

Age: Up-Down-Down

CCDC151 2.625 0.778 - - 0.880 - 0.967 Mlig455_024997 {REF} {Length: 2376} {TRANSSPLICED} {Human: ENSG00000198003, CCDC151, coiled-coil domain containing 151, [Score=251, Expect=5e-75]} {Mouse: ENSMUSG00000039632, Ccdc151, coiled-coil domain containing 151, [Score=261, Expect=4e-79]} {Dmel: FBgn0036219, CCDC151, Coiled-coil domain containing protein 151, [Score=111, Expect=2e-25]} {Smed: dd_Smed_v6_4526_0_1, dd_Smed_v6_4526_0_1, [Score=463, Expect=3e-158]} {RNA1509_18758} {RNA1310_9513.1, RNA1509_18758} {RNA1509_18758, RNA815_13766}
34. MligTC455_20294 341 7.11 Mlig455_007896, Mlig455_008003

Neo: -

Age: Up-Down-Down

Region-enriched R8: 3.032/0.04842

LRRK2 2.595 - - 0.839 0.770 - 0.986

Mlig455_007896 {REF} {Length: 11344} {TRANSSPLICED} {Pfam: C-terminal of Roc, COR, domain [PF16095.7, score=164.1]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=71.6]; TIR domain [PF13676.8, score=57.4]; Leucine rich repeat [PF13855.8, score=43.0]; Ras family [PF00071.24, score=38.2]; Leucine Rich repeats (2 copies) [PF12799.9, score=24.8]} {Human: ENSG00000188906, LRRK2, leucine rich repeat kinase 2, [Score=167, Expect=3e-40]} {Mouse: ENSMUSG00000036273, Lrrk2, leucine-rich repeat kinase 2, [Score=166, Expect=5e-40]} {Dmel: FBgn0038816, Lrrk, Leucine-rich repeat kinase, [Score=145, Expect=7e-34]} {Celegans: WBGene00003068, lrk-1, Leucine-rich repeat serine/threonine-protein kinase 1, [Score=125, Expect=4e-28]} {Smed: dd_Smed_v6_12105_0_1, dd_Smed_v6_12105_0_1, [Score=723, Expect=0.0]} {RNA1509_8727} {RNA1310_292.1, RNA1509_8727} {RNA1509_8727, RNA815_1320}

Mlig455_008003 {REF} {Length: 11209} {TRANSSPLICED} {Pfam: C-terminal of Roc, COR, domain [PF16095.7, score=160.9]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=72.4]; TIR domain [PF13676.8, score=59.5]; Leucine rich repeat [PF13855.8, score=45.2]; Ras family [PF00071.24, score=39.6]; Leucine Rich repeats (2 copies) [PF12799.9, score=28.4]} {Human: ENSG00000188906, LRRK2, leucine rich repeat kinase 2, [Score=167, Expect=1e-40]} {Mouse: ENSMUSG00000036273, Lrrk2, leucine-rich repeat kinase 2, [Score=163, Expect=1e-39]} {Dmel: FBgn0038816, Lrrk, Leucine-rich repeat kinase, [Score=145, Expect=4e-34]} {Celegans: WBGene00003068, lrk-1, Leucine-rich repeat serine/threonine-protein kinase 1, [Score=120, Expect=1e-26]} {Smed: dd_Smed_v6_12105_0_1, dd_Smed_v6_12105_0_1, [Score=686, Expect=0.0]} {RNA1509_8727} {RNA1310_292.1} {RNA815_1320}
35. MligTC455_39988 83 1.73 Mlig455_062081

Neo: -

Age: -

2.594 - - - 0.725 0.913 0.956 Mlig455_062081 {REF} {Length: 447} {NoTransDecoderORF} {RNA1509_50426} {RNA1310_88257} {RNA815_17173.4}
36. MligTC455_41119 1169 24.34 Mlig455_058911

Neo: -

Age: logFC(26M/2M)=-0.387

WDR78 2.585 - - 0.794 0.822 - 0.969 Mlig455_058911 {REF} {Length: 2881} {Pfam: WD domain, G-beta repeat [PF00400.34, score=54.0]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=36.7]} {Human: ENSG00000152763, WDR78, WD repeat domain 78, [RH, Score=446, Expect=3e-144]} {Mouse: ENSMUSG00000035126, Wdr78, WD repeat domain 78, [RH, Score=425, Expect=1e-136]} {Dmel: FBgn0263988, Dic61B, Dynein intermediate chain at 61B, [RH, Score=177, Expect=2e-46]} {Celegans: WBGene00015927, dyci-1, DYnein Chain, light Intermediate, [Score=97.1, Expect=1e-20]} {Smed: dd_Smed_v6_8721_0_1, dd_Smed_v6_8721_0_1, [RH, Score=604, Expect=0.0]} {RNA1509_29266, RNA1509_46859, RNA1509_6167} {RNA1310_6865, RNA1509_29266, RNA1509_46859, RNA1509_6167} {RNA1509_29266, RNA1509_46859, RNA1509_6167, RNA815_2311}
37. MligTC455_16872 306 6.37 Mlig455_006228

Neo: -

Age: -

Region-specific R2: 5.842

Region-enriched R2: 4.577/0.00000

2.576 0.915 - - 0.704 - 0.957 Mlig455_006228 {REF} {Length: 952} {RNA1310_48111} {RNA815_24753}
38. MligTC455_41537 411 8.57 Mlig455_058671

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.369

CCDC170 2.565 - - 0.852 0.760 - 0.953 Mlig455_058671 {REF} {Length: 4116} {Human: ENSG00000120262, CCDC170, coiled-coil domain containing 170, [RH, Score=284, Expect=8e-84]} {Mouse: ENSMUSG00000019767, Ccdc170, coiled-coil domain containing 170, [RH, Score=274, Expect=4e-80]} {Dmel: FBgn0263079, CG43338, [RH, Score=117, Expect=1e-26]} {Smed: dd_Smed_v6_10140_0_1, dd_Smed_v6_10140_0_1, [RH, Score=304, Expect=4e-91]} {RNA1509_3115} {RNA1310_2598, RNA1509_3115} {RNA1509_3115, RNA815_746}
39. MligTC455_32922 646 13.45 Mlig455_037744, Mlig455_069919

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.335

Region-enriched R2: 1.859/0.01146

ANXA4 2.564 - - - 0.779 0.814 0.971

Mlig455_037744 {REF} {Length: 3044} {TRANSSPLICED} {Pfam: Annexin [PF00191.22, score=312.1]; Fn3 associated [PF13287.8, score=30.9]; Chitobiase/beta-hexosaminidase C-terminal domain [PF13290.8, score=27.1]} {Human: ENSG00000196975, ANXA4, annexin A4, [RH, Score=330, Expect=1e-106]; ENSG00000122359, ANXA11, annexin A11, [RH, Score=318, Expect=6e-100]} {Mouse: ENSMUSG00000029994, Anxa4, annexin A4, [RH, Score=328, Expect=2e-106]; ENSMUSG00000021866, Anxa11, annexin A11, [RH, Score=317, Expect=2e-99]} {Dmel: FBgn0030749, AnxB11, Annexin B11, [RH, Score=318, Expect=6e-100]} {Celegans: WBGene00003589, nex-2, Annexin, [RH, Score=298, Expect=7e-93]} {Smed: dd_Smed_v6_5798_0_1, dd_Smed_v6_5798_0_1, [RH, Score=726, Expect=0.0]} {RNA1509_19722} {RNA1310_5582} {RNA815_3942.1}

Mlig455_069919 {REF} {Length: 3044} {TRANSSPLICED} {Pfam: Annexin [PF00191.22, score=308.6]; Fn3 associated [PF13287.8, score=30.9]; Chitobiase/beta-hexosaminidase C-terminal domain [PF13290.8, score=27.1]} {Human: ENSG00000196975, ANXA4, annexin A4, [RH, Score=330, Expect=6e-107]; ENSG00000122359, ANXA11, annexin A11, [RH, Score=316, Expect=3e-99]} {Mouse: ENSMUSG00000029994, Anxa4, annexin A4, [RH, Score=329, Expect=1e-106]; ENSMUSG00000021866, Anxa11, annexin A11, [RH, Score=315, Expect=1e-98]} {Dmel: FBgn0030749, AnxB11, Annexin B11, [RH, Score=316, Expect=3e-99]} {Celegans: WBGene00003589, nex-2, Annexin, [RH, Score=297, Expect=3e-92]} {Smed: dd_Smed_v6_5798_0_1, dd_Smed_v6_5798_0_1, [RH, Score=726, Expect=0.0]} {RNA1509_19722, RNA1509_52903} {RNA1310_5582, RNA1509_19722, RNA1509_52903} {RNA1509_19722, RNA1509_52903, RNA815_3942.1}
40. MligTC455_22098 31 0.66 Mlig455_004396, Mlig455_037219

Neo: -

Age: -

2.563 - - 0.782 0.830 - 0.951

Mlig455_004396 {REF} {Length: 1521} {RNA1310_40784}

Mlig455_037219 {REF} {Length: 1583} {RNA1310_63625}
41. MligTC455_43324 71 1.47 Mlig455_041984

Neo: -

Age: -

Region-enriched R2: 6.623/0.00573

2.559 - - - 0.774 0.827 0.958 Mlig455_041984 {REF} {Length: 388} {NoTransDecoderORF} {RNA1509_49821} {RNA1310_52560.2} {RNA815_59873}
42. MligTC455_41358 245 5.1 Mlig455_029627

Neo: -

Age: -

PPP1R42 2.557 - 0.712 - - 0.872 0.973 Mlig455_029627 {REF} {Length: 2517} {Pfam: Leucine Rich repeats (2 copies) [PF12799.9, score=62.4]; Leucine rich repeat [PF13855.8, score=47.1]; Leucine-rich repeat [PF14580.8, score=35.6]} {Human: ENSG00000178125, PPP1R42, protein phosphatase 1 regulatory subunit 42, [RH, Score=211, Expect=7e-66]} {Mouse: ENSMUSG00000025916, Ppp1r42, protein phosphatase 1, regulatory subunit 42, [RH, Score=196, Expect=1e-59]} {Dmel: FBgn0046697, Ppr-Y, [Score=53.5, Expect=1e-07]} {Celegans: WBGene00189952, K10D2.8, [Score=56.6, Expect=7e-09]} {Smed: dd_Smed_v6_7268_1_2, dd_Smed_v6_7268_1_2, [RH, Score=228, Expect=3e-73]} {RNA1509_39009, RNA1509_39771} {RNA1310_21948.1, RNA1509_39009, RNA1509_39771} {RNA1509_39009, RNA1509_39771, RNA815_20117}
43. MligTC455_36078 21 0.44 Mlig455_032513

Neo: -

Age: -

2.532 - - 0.705 - 0.861 0.966 Mlig455_032513 {REF} {Length: 503} {NoTransDecoderORF} {RNA1509_45539} {RNA1310_77014} {RNA815_40738}
44. MligTC455_21721 1177 24.51 Mlig455_052943, Mlig455_053013

Neo: -

Age: -

TRPM3 2.53 - - 0.751 0.804 - 0.975

Mlig455_052943 {REF} {Length: 4423} {TRANSSPLICED} {Pfam: SLOG in TRPM [PF18139.3, score=222.0]; SLOG in TRPM, prokaryote [PF18171.3, score=68.5]; Ion transport protein [PF00520.33, score=52.7]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [RH, Score=521, Expect=2e-158]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [RH, Score=522, Expect=1e-158]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=484, Expect=1e-149]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=362, Expect=8e-104]} {Smed: dd_Smed_v6_13119_0_1, dd_Smed_v6_13119_0_1, [Score=607, Expect=0.0]} {RNA1509_4847} {RNA1310_1801.1} {RNA815_652.1}

Mlig455_053013 {REF} {Length: 4421} {TRANSSPLICED} {Pfam: SLOG in TRPM [PF18139.3, score=222.1]; SLOG in TRPM, prokaryote [PF18171.3, score=68.5]; Ion transport protein [PF00520.33, score=53.1]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [RH, Score=517, Expect=8e-157]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [RH, Score=519, Expect=2e-157]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=482, Expect=8e-149]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=363, Expect=2e-104]} {Smed: dd_Smed_v6_13119_0_1, dd_Smed_v6_13119_0_1, [Score=605, Expect=0.0]} {RNA1509_4847} {RNA1310_1801.1, RNA1509_4847} {RNA1509_4847, RNA815_652.1}
45. MligTC455_29451 819 17.07 Mlig455_026453

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.590

LMNTD1 2.527 - - - 0.832 0.735 0.960 Mlig455_026453 {REF} {Length: 3415} {Pfam: Intermediate filament protein [PF00038.23, score=53.0]; Lamin Tail Domain [PF00932.21, score=40.2]; Mechanosensitive ion channel porin domain [PF12795.9, score=18.4]} {Human: ENSG00000152936, LMNTD1, lamin tail domain containing 1, [RH, Score=148, Expect=6e-38]} {Mouse: ENSMUSG00000054966, Lmntd1, lamin tail domain containing 1, [RH, Score=140, Expect=2e-35]} {Dmel: FBgn0002525, Lam, Lamin, [Score=72.4, Expect=1e-12]} {Celegans: WBGene00002051, ifa-3, Intermediate filament protein ifa-3, [Score=62.0, Expect=1e-09]} {Smed: dd_Smed_v6_10248_0_1, dd_Smed_v6_10248_0_1, [RH, Score=405, Expect=7e-127]} {RNA1509_7063} {RNA1310_3989.1} {RNA815_1147.1}
46. MligTC455_18683 419 8.74 Mlig455_069928

Neo: -

Age: -

Region-specific R2: 6.066

Region-enriched R2: 4.921/0.00217

2.523 0.842 - - 0.723 - 0.958 Mlig455_069928 {REF} {Length: 845} {RNA1509_25826} {RNA1310_42757} {RNA815_23874}
47. MligTC455_29452 881 18.34 Mlig455_044747

Neo: -

Age: -

LMNTD1 2.517 - - - 0.823 0.733 0.961 Mlig455_044747 {REF} {Length: 9990} {tRNA: Phe(GAA), score=86.5} {Pfam: Intermediate filament protein [PF00038.23, score=53.6]; Lamin Tail Domain [PF00932.21, score=40.3]; Mechanosensitive ion channel porin domain [PF12795.9, score=20.9]} {Human: ENSG00000152936, LMNTD1, lamin tail domain containing 1, [RH, Score=146, Expect=3e-37]} {Mouse: ENSMUSG00000054966, Lmntd1, lamin tail domain containing 1, [RH, Score=140, Expect=3e-35]} {Dmel: FBgn0002525, Lam, Lamin, [Score=72.4, Expect=1e-12]} {Celegans: WBGene00002051, ifa-3, Intermediate filament protein ifa-3, [Score=62.8, Expect=8e-10]} {Smed: dd_Smed_v6_10248_0_1, dd_Smed_v6_10248_0_1, [Score=208, Expect=5e-56]} {RNA1509_20212} {RNA1310_1500.1} {RNA815_1147.1}
48. MligTC455_29450 827 17.23 Mlig455_026424

Neo: -

Age: logFC(26M/2M)=-0.523

LMNTD1 2.515 - - - 0.830 0.723 0.962 Mlig455_026424 {REF} {Length: 3702} {Pfam: Intermediate filament protein [PF00038.23, score=52.8]; Lamin Tail Domain [PF00932.21, score=40.5]} {Human: ENSG00000152936, LMNTD1, lamin tail domain containing 1, [RH, Score=147, Expect=1e-37]} {Mouse: ENSMUSG00000054966, Lmntd1, lamin tail domain containing 1, [RH, Score=142, Expect=7e-36]} {Dmel: FBgn0002525, Lam, Lamin, [Score=72.8, Expect=9e-13]} {Celegans: WBGene00002051, ifa-3, Intermediate filament protein ifa-3, [Score=62.4, Expect=9e-10]} {Smed: dd_Smed_v6_10248_0_1, dd_Smed_v6_10248_0_1, [RH, Score=228, Expect=1e-62]} {RNA1509_16713, RNA1509_7063} {RNA1310_3989.1, RNA1509_16713, RNA1509_7063} {RNA1509_16713, RNA1509_7063, RNA815_1147.1}
49. MligTC455_16416 290 6.04 Mlig455_000468

Neo: -

Age: -

Region-enriched R2: 2.225/0.04782

ROR1 2.511 - 0.735 - 0.794 - 0.982 Mlig455_000468 {REF} {Length: 2686} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=208.1]; Protein kinase domain [PF00069.27, score=77.3]; Kringle domain [PF00051.20, score=19.4]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [Score=300, Expect=1e-89]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [Score=295, Expect=2e-87]; ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [Score=281, Expect=2e-82]} {Dmel: FBgn0010407, Ror, [Score=259, Expect=2e-76]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=217, Expect=2e-60]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [Score=328, Expect=1e-100]} {RNA1509_35395} {RNA1310_13558} {RNA815_27446}
50. MligTC455_22762 328 6.84 Mlig455_036232

Neo: -

Age: logFC(26M/2M)=0.467

ELOVL4 2.511 - - 0.781 0.766 - 0.964 Mlig455_036232 {REF} {Length: 1770} {TRANSSPLICED} {Pfam: GNS1/SUR4 family [PF01151.20, score=205.6]} {Human: ENSG00000118402, ELOVL4, ELOVL fatty acid elongase 4, [RH, Score=308, Expect=2e-104]} {Mouse: ENSMUSG00000032262, Elovl4, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4, [RH, Score=304, Expect=5e-103]} {Dmel: FBgn0052072, Elo68alpha, Elongase 68alpha, [RH, Score=214, Expect=2e-68]} {Celegans: WBGene00001245, elo-7, Elongation of very long chain fatty acids protein, [Score=81.3, Expect=1e-17]} {Smed: dd_Smed_v6_7835_0_1, dd_Smed_v6_7835_0_1, [Score=308, Expect=2e-105]} {RNA1509_11261} {RNA1310_21427.1} {RNA815_6649.1}
51. MligTC455_43741 196 4.08 Mlig455_018088

Neo: -

Age: Down-Up-Down

PTBP1 2.511 - - 0.786 0.759 - 0.966 Mlig455_018088 {REF} {Length: 2775} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF13893.8, score=116.9]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=52.7]; Occluded RNA-recognition motif [PF16842.7, score=26.8]} {Human: ENSG00000011304, PTBP1, polypyrimidine tract binding protein 1, [Score=258, Expect=8e-80]; ENSG00000117569, PTBP2, polypyrimidine tract binding protein 2, [Score=258, Expect=1e-80]; ENSG00000119314, PTBP3, polypyrimidine tract binding protein 3, [Score=248, Expect=1e-76]} {Mouse: ENSMUSG00000028134, Ptbp2, polypyrimidine tract binding protein 2, [Score=258, Expect=7e-81]; ENSMUSG00000006498, Ptbp1, polypyrimidine tract binding protein 1, [Score=251, Expect=1e-78]; ENSMUSG00000028382, Ptbp3, polypyrimidine tract binding protein 3, [Score=248, Expect=1e-77]} {Dmel: FBgn0011224, heph, hephaestus, [Score=249, Expect=7e-78]} {Celegans: WBGene00004207, ptb-1, PTB (HnRNP) homolog; Putative RNA-binding protein PTB-1b, [Score=234, Expect=1e-72]} {Smed: dd_Smed_v6_1868_0_1, dd_Smed_v6_1868_0_1, [Score=214, Expect=4e-64]} {RNA1509_36451} {RNA1310_3345} {RNA815_23519}
52. MligTC455_19278 4335 90.31 Mlig455_057304, Mlig455_070944

Neo: -

Age: logFC(26M/2M)=0.686

Region-specific R2: 5.590

Region-enriched R2: 5.465/0.00000
Region-enriched R3: 2.308/0.00629

CHRNA10 2.507 0.768 - - 0.786 - 0.953

Mlig455_057304 {REF} {Length: 1001} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=71.6]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=77.0, Expect=2e-16]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=75.9, Expect=4e-16]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=75.5, Expect=6e-16]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=73.9, Expect=2e-15]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=93.6, Expect=2e-22]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=100, Expect=5e-25]} {Smed: dd_Smed_v6_11955_0_1, dd_Smed_v6_11955_0_1, [Score=82.8, Expect=8e-19]} {RNA1509_23115} {RNA1310_34970} {RNA815_15305.1}

Mlig455_070944 {REF} {Length: 1060} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=88.2]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=95.9, Expect=6e-22]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=96.3, Expect=3e-22]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=94.7, Expect=1e-21]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=112, Expect=7e-28]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=118, Expect=4e-30]} {Smed: dd_Smed_v6_18184_0_1, dd_Smed_v6_18184_0_1, [Score=98.6, Expect=2e-23]} {RNA1509_23115, RNA1509_43907, RNA1509_9432} {RNA1310_34970, RNA1509_23115, RNA1509_43907, RNA1509_9432} {RNA1509_23115, RNA1509_43907, RNA1509_9432, RNA815_15305.1}
53. MligTC455_22761 288 6.01 Mlig455_005521

Neo: -

Age: -

ELOVL4 2.501 - - 0.741 0.795 - 0.965 Mlig455_005521 {REF} {Length: 1592} {TRANSSPLICED} {Pfam: GNS1/SUR4 family [PF01151.20, score=138.3]} {Human: ENSG00000118402, ELOVL4, ELOVL fatty acid elongase 4, [Score=220, Expect=1e-70]} {Mouse: ENSMUSG00000032262, Elovl4, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4, [Score=216, Expect=1e-69]} {Dmel: FBgn0052072, Elo68alpha, Elongase 68alpha, [Score=145, Expect=2e-42]} {Celegans: WBGene00001244, elo-6, Elongation of very long chain fatty acids protein 6, [Score=52.8, Expect=4e-08]} {Smed: dd_Smed_v6_7835_0_1, dd_Smed_v6_7835_0_1, [Score=215, Expect=7e-70]} {RNA1509_11261} {RNA1310_42181} {RNA815_6649.1}
54. MligTC455_35259 2265 47.19 Mlig455_040978

Neo: -

Age: Up-Down-Down

Region-specific R2: 2.606

Region-enriched R2: 1.588/0.00387

ADGRL2 2.5 0.756 - - 0.772 - 0.972 Mlig455_040978 {REF} {Length: 10808} {TRANSSPLICED} {Pfam: PDZ domain [PF00595.26, score=86.9]; 7 transmembrane receptor (Secretin family) [PF00002.26, score=76.2]; PDZ domain [PF17820.3, score=67.3]; GPCR proteolysis site, GPS, motif [PF01825.23, score=52.3]; PDZ domain [PF13180.8, score=36.4]; ZU5 domain [PF00791.22, score=30.8]; Guanylate kinase [PF00625.23, score=22.4]} {Human: ENSG00000117114, ADGRL2, adhesion G protein-coupled receptor L2, [RH, Score=174, Expect=1e-42]} {Mouse: ENSMUSG00000034917, Tjp3, tight junction protein 3, [RH, Score=172, Expect=9e-43]} {Dmel: FBgn0262614, pyd, polychaetoid, [RH, Score=232, Expect=8e-61]} {Celegans: WBGene00013683, zoo-1, ZO-1 (Zonula Occludens tight junctional protein) Ortholog, [Score=174, Expect=4e-43]} {Smed: dd_Smed_v6_8425_0_1, dd_Smed_v6_8425_0_1, [RH, Score=833, Expect=0.0]} {RNA1509_17602, RNA1509_52679, RNA1509_58629} {RNA1310_236.2, RNA1509_17602, RNA1509_58629} {RNA1509_17602, RNA1509_58629, RNA815_77.1}
55. MligTC455_20142 488 10.17 Mlig455_036513

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=-0.225

2.497 - - 0.786 0.753 - 0.958 Mlig455_036513 {REF} {Length: 1074} {NoTransDecoderORF} {RNA1509_4350} {RNA1310_20554, RNA1509_4350} {RNA1509_4350, RNA815_8810.1}
56. MligTC455_16002 752 15.67 Mlig455_062545

Neo: -

Age: -

TTC16 2.496 - - 0.757 - 0.765 0.974 Mlig455_062545 {REF} {Length: 2280} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF07719.19, score=82.7]; Tetratricopeptide repeat [PF00515.30, score=64.9]; TPR repeat [PF13414.8, score=58.1]; Tetratricopeptide repeat [PF13432.8, score=57.0]; Tetratricopeptide repeat [PF13181.8, score=56.4]; Tetratricopeptide repeat [PF13428.8, score=54.2]; Tetratricopeptide repeat [PF14559.8, score=42.2]; Tetratricopeptide repeat [PF13424.8, score=41.4]; Tetratricopeptide repeat [PF13371.8, score=32.2]; Tetratricopeptide repeat [PF13176.8, score=31.2]; Tetratricopeptide repeat [PF13431.8, score=24.0]; NMDA receptor-regulated protein 1 [PF12569.10, score=23.7]; Tetratricopeptide repeat [PF13174.8, score=21.3]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=19.2]} {Human: ENSG00000167094, TTC16, tetratricopeptide repeat domain 16, [RH, Score=291, Expect=3e-86]} {Mouse: ENSMUSG00000039021, Ttc16, tetratricopeptide repeat domain 16, [RH, Score=295, Expect=9e-89]} {Celegans: WBGene00000500, chn-1, C-term of Hsp70-iNteracting protein (CHIP family); Hsp70-interacting protein, [Score=50.8, Expect=1e-06]} {Smed: dd_Smed_v6_11894_0_1, dd_Smed_v6_11894_0_1, [RH, Score=447, Expect=1e-147]} {RNA1509_9009} {RNA1310_10645.1, RNA1509_9009} {RNA1509_9009, RNA815_3627}
57. MligTC455_41035 366 7.62 Mlig455_000866

Neo: -

Age: logFC(26M/2M)=-0.773

Region-specific R2: 5.029

Region-enriched R2: 4.768/0.00000

2.496 0.803 - 0.737 - - 0.956 Mlig455_000866 {REF} {Length: 1126} {Pfam: Pancreatic hormone peptide [PF00159.20, score=41.6]} {RNA1509_27581} {RNA1310_74103, RNA1509_27581} {RNA1509_27581, RNA815_38377}
58. MligTC455_29045 127 2.65 Mlig455_056054

Neo: -

Age: -

Region-enriched R2: 4.858/0.00652

FZD5 2.494 - - 0.788 0.747 - 0.959 Mlig455_056054 {REF} {Length: 3655} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=389.0]; Fz domain [PF01392.24, score=85.2]} {Human: ENSG00000163251, FZD5, frizzled class receptor 5, [Score=554, Expect=0.0]} {Mouse: ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [Score=561, Expect=0.0]} {Dmel: FBgn0016797, fz2, frizzled 2, [Score=516, Expect=5e-176]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=368, Expect=3e-120]} {Smed: dd_Smed_v6_16571_0_1, dd_Smed_v6_16571_0_1, [Score=522, Expect=7e-178]} {RNA1509_35313} {RNA1310_9623.1} {RNA815_2562.1}
59. MligTC455_50664 138 2.87 Mlig455_035152

Neo: -

Age: -

Region-enriched R2: 3.712/0.01441

LRRC74A 2.494 - - 0.811 0.732 - 0.951 Mlig455_035152 {REF} {Length: 2523} {TRANSSPLICED} {Pfam: Leucine Rich repeat [PF13516.8, score=68.7]; Leucine Rich Repeat [PF00560.35, score=35.6]; Leucine Rich repeats (2 copies) [PF12799.9, score=31.8]; Leucine rich repeat [PF13855.8, score=22.7]} {Human: ENSG00000100565, LRRC74A, leucine rich repeat containing 74A, [Score=146, Expect=1e-37]; ENSG00000187905, LRRC74B, leucine rich repeat containing 74B, [Score=144, Expect=1e-37]} {Mouse: ENSMUSG00000059114, Lrrc74a, leucine rich repeat containing 74A, [Score=147, Expect=5e-38]; ENSMUSG00000022759, Lrrc74b, leucine rich repeat containing 74B, [Score=144, Expect=1e-37]} {Dmel: FBgn0033212, LRR, Leucine-rich repeat, [Score=51.6, Expect=2e-06]} {Celegans: WBGene00009201, F28C1.3, Protein phosphatase 1 regulatory subunit 37 homolog, [Score=55.5, Expect=8e-08]} {Smed: dd_Smed_v6_14506_0_1, dd_Smed_v6_14506_0_1, [Score=147, Expect=6e-38]} {RNA1509_21228} {RNA1310_12842} {RNA815_17243}
60. MligTC455_15492 69 1.44 Mlig455_022488

Neo: -

Age: Down-Up-Up

2.493 - - 0.788 0.752 - 0.953 Mlig455_022488 {REF} {Length: 1351} {RNA1310_26051} {RNA815_10966}
61. MligTC455_52874 382 7.96 Mlig455_026014, Mlig455_070442

Neo: -

Age: -

CDH23 2.493 - - - 0.823 0.708 0.962

Mlig455_026014 {REF} {Length: 10931} {TRANSSPLICED} {Pfam: Cadherin domain [PF00028.19, score=362.8]; Cadherin-like [PF16184.7, score=40.0]; Cadherin-like [PF08266.14, score=32.1]} {Human: ENSG00000107736, CDH23, cadherin related 23, [Score=327, Expect=4e-90]} {Mouse: ENSMUSG00000012819, Cdh23, cadherin 23 (otocadherin), [Score=327, Expect=2e-90]} {Dmel: FBgn0038247, Cad88C, Cadherin 88C, [Score=404, Expect=8e-116]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=211, Expect=1e-54]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [Score=498, Expect=9e-149]} {RNA1509_48951} {RNA1310_475.1} {RNA815_321.1}

Mlig455_070442 {REF} {Length: 10801} {TRANSSPLICED} {Pfam: Cadherin domain [PF00028.19, score=364.1]; Cadherin-like [PF16184.7, score=39.7]; Cadherin-like [PF08266.14, score=30.9]} {Human: ENSG00000107736, CDH23, cadherin related 23, [Score=323, Expect=4e-89]} {Mouse: ENSMUSG00000012819, Cdh23, cadherin 23 (otocadherin), [Score=326, Expect=4e-90]} {Dmel: FBgn0038247, Cad88C, Cadherin 88C, [Score=404, Expect=8e-116]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=211, Expect=1e-54]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [Score=495, Expect=1e-147]} {RNA1509_44393, RNA1509_48951} {RNA1310_475.1, RNA1509_44393} {RNA1509_44393, RNA815_321.1}
62. MligTC455_53414 331 6.9 Mlig455_053442

Neo: -

Age: -

Region-specific R2: 4.308

Region-enriched R2: 3.374/0.00040

RP1 2.493 0.783 - - 0.751 - 0.959 Mlig455_053442 {REF} {Length: 1156} {Pfam: PLAT/LH2 domain [PF01477.25, score=155.8]; Doublecortin [PF03607.19, score=103.5]; Embryo-specific protein 3, (ATS3) [PF06232.13, score=22.0]} {Human: ENSG00000104237, RP1, RP1, axonemal microtubule associated, [Score=473, Expect=5e-146]} {Mouse: ENSMUSG00000025900, Rp1, retinitis pigmentosa 1 (human), [Score=454, Expect=1e-136]} {Dmel: FBgn0261387, CG17528, [Score=56.6, Expect=1e-07]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [Score=75.5, Expect=2e-13]} {Smed: dd_Smed_v6_10315_0_2, dd_Smed_v6_10315_0_2, [Score=698, Expect=0.0]} {RNA1509_21828} {RNA1310_33070.1} {RNA815_13802.1}
63. MligTC455_53415 319 6.64 Mlig455_053444

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.862

Region-enriched R2: 4.179/0.00011

RP1 2.49 0.783 - - 0.750 - 0.957 Mlig455_053444 {REF} {Length: 4944} {Pfam: PLAT/LH2 domain [PF01477.25, score=155.3]; Doublecortin [PF03607.19, score=100.5]; Embryo-specific protein 3, (ATS3) [PF06232.13, score=22.5]; Fibroblast growth factor [PF00167.20, score=18.6]} {Human: ENSG00000104237, RP1, RP1, axonemal microtubule associated, [Score=471, Expect=6e-145]} {Mouse: ENSMUSG00000025900, Rp1, retinitis pigmentosa 1 (human), [Score=453, Expect=3e-136]} {Dmel: FBgn0261387, CG17528, [Score=56.6, Expect=1e-07]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [Score=75.9, Expect=1e-13]} {Smed: dd_Smed_v6_10315_0_2, dd_Smed_v6_10315_0_2, [Score=691, Expect=0.0]} {RNA1509_59703} {RNA1310_2710} {RNA815_17469}
64. MligTC455_31845 109 2.26 Mlig455_009355, Mlig455_021094, Mlig455_021098, Mlig455_044178, Mlig455_044180

Neo: Int S/G2/M

Age: -

2.485 - - 0.749 - 0.780 0.956

Mlig455_009355 {REF} {Length: 800} {NoTransDecoderORF} {RNA1310_33360} {RNA815_55952}

Mlig455_021094 {REF} {Length: 811} {NoTransDecoderORF} {RNA1310_33360} {RNA815_55952}

Mlig455_021098 {REF} {Length: 2489} {RNA1509_38652} {RNA1310_33360} {RNA815_42706}

Mlig455_044178 {REF} {Length: 627} {NoTransDecoderORF} {RNA1310_32755} {RNA815_14068}

Mlig455_044180 {REF} {Length: 758} {NoTransDecoderORF} {RNA1310_32755} {RNA815_14068}
65. MligTC455_29204 333 6.93 Mlig455_052247

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.586

ANK3 2.484 - - 0.814 - 0.718 0.952 Mlig455_052247 {REF} {Length: 5485} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=62.8]; Ankyrin repeats (many copies) [PF13637.8, score=51.6]; Ankyrin repeat [PF00023.32, score=40.1]; Ankyrin repeat [PF13606.8, score=38.1]; Ankyrin repeats (many copies) [PF13857.8, score=34.4]; Mab-21 protein [PF03281.16, score=20.6]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=65.9, Expect=3e-10]} {Mouse: ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=65.9, Expect=2e-10]} {Dmel: FBgn0031473, CG3104, [Score=74.3, Expect=6e-14]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=58.2, Expect=2e-08]} {Smed: dd_Smed_v6_9936_0_1, dd_Smed_v6_9936_0_1, [Score=70.5, Expect=2e-12]} {RNA1509_39688} {RNA1310_6142.1} {RNA815_6750.1}
66. MligTC455_47948 100 2.07 Mlig455_005840

Neo: -

Age: -

Region-enriched R2: 3.643/0.03527

TSPAN16 2.484 - - - 0.793 0.740 0.951 Mlig455_005840 {REF} {Length: 2130} {Pfam: Tetraspanin family [PF00335.22, score=86.4]} {Human: ENSG00000130167, TSPAN16, tetraspanin 16, [Score=48.1, Expect=6e-06]} {Mouse: ENSMUSG00000025351, Cd63, CD63 antigen, [Score=50.4, Expect=7e-07]} {Dmel: FBgn0036769, Tsp74F, Tetraspanin 74F, [Score=68.2, Expect=4e-13]} {Smed: dd_Smed_v6_854_1_1, dd_Smed_v6_854_1_1, [Score=119, Expect=5e-32]} {RNA1509_35459} {RNA1310_22253, RNA1509_35459} {RNA1509_35459, RNA815_11065}
67. MligTC455_18501 200 4.16 Mlig455_031954

Neo: -

Age: Down-Up-Up

2.483 - 0.801 - 0.953 - 0.729 Mlig455_031954 {REF} {Length: 1030} {RNA1509_49054} {RNA1310_32906} {RNA815_15169}
68. MligTC455_29203 334 6.95 Mlig455_037140

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.614

2.478 - - 0.820 - 0.706 0.952 Mlig455_037140 {REF} {Length: 5032} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=37.3]; Ankyrin repeat [PF00023.32, score=28.8]; Ankyrin repeat [PF13606.8, score=25.8]; Ankyrin repeats (many copies) [PF13637.8, score=24.6]; Ankyrin repeats (many copies) [PF13857.8, score=22.2]; Mab-21 protein [PF03281.16, score=20.5]} {RNA1509_39416} {RNA1310_14401} {RNA815_5545.1}
69. MligTC455_41181 708 14.76 Mlig455_049760

Neo: -

Age: logFC(26M/2M)=-0.377

Region-enriched R2: 2.010/0.02984

AK5 2.477 0.799 - 0.711 - - 0.967 Mlig455_049760 {REF} {Length: 2835} {TRANSSPLICED} {Pfam: Adenylate kinase [PF00406.24, score=105.1]; AAA domain [PF13207.8, score=87.6]; AAA domain [PF13238.8, score=49.8]; AAA domain [PF13671.8, score=35.6]; IQ calmodulin-binding motif [PF00612.29, score=33.6]; AAA ATPase domain [PF13191.8, score=29.8]; AAA domain [PF13521.8, score=22.3]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=20.4]; AAA domain [PF13245.8, score=20.1]} {Human: ENSG00000154027, AK5, adenylate kinase 5, [RH, Score=223, Expect=6e-64]} {Mouse: ENSMUSG00000039058, Ak5, adenylate kinase 5, [RH, Score=222, Expect=1e-63]} {Dmel: FBgn0032083, CG9541, [RH, Score=109, Expect=1e-24]} {Celegans: WBGene00008746, F13E6.2, [Score=126, Expect=7e-30]} {Smed: dd_Smed_v6_5119_0_1, dd_Smed_v6_5119_0_1, [RH, Score=266, Expect=1e-77]} {RNA1509_14765, RNA1509_30132} {RNA1310_6179.1, RNA1509_14765, RNA1509_30132} {RNA1509_14765, RNA1509_30132, RNA815_3037}
70. MligTC455_40654 676 14.08 Mlig455_056785

Neo: -

Age: logFC(26M/2M)=-0.402

CCDC63 2.476 - 0.735 - 0.758 - 0.983 Mlig455_056785 {REF} {Length: 2093} {TRANSSPLICED} {Pfam: Initiation control protein YabA [PF06156.15, score=20.5]} {Human: ENSG00000173093, CCDC63, coiled-coil domain containing 63, [RH, Score=190, Expect=9e-53]} {Mouse: ENSMUSG00000043036, Ccdc63, coiled-coil domain containing 63, [RH, Score=179, Expect=7e-49]} {Dmel: FBgn0038452, CG14905, [RH, Score=168, Expect=6e-46]} {Smed: dd_Smed_v6_4191_0_1, dd_Smed_v6_4191_0_1, [RH, Score=442, Expect=7e-150]} {RNA1509_17628} {RNA1310_12386, RNA1509_17628} {RNA1509_17628, RNA815_7054}
71. MligTC455_48827 761 15.86 Mlig455_042518

Neo: -

Age: logFC(26M/2M)=-0.412

ANO7 2.466 - - 0.725 0.765 - 0.976 Mlig455_042518 {REF} {Length: 4110} {Pfam: Calcium-activated chloride channel [PF04547.14, score=290.9]; Dimerisation domain of Ca+-activated chloride-channel, anoctamin [PF16178.7, score=33.9]} {Human: ENSG00000146205, ANO7, anoctamin 7, [Score=164, Expect=8e-41]} {Mouse: ENSMUSG00000034107, Ano7, anoctamin 7, [Score=165, Expect=1e-41]; ENSMUSG00000031075, Ano1, anoctamin 1, calcium activated chloride channel, [Score=160, Expect=1e-39]; ENSMUSG00000064210, Ano6, anoctamin 6, [Score=157, Expect=4e-39]} {Dmel: FBgn0030349, CG10353, [Score=157, Expect=6e-39]} {Celegans: WBGene00010138, anoh-1, Anoctamin, [Score=263, Expect=3e-75]} {Smed: dd_Smed_v6_19189_0_1, dd_Smed_v6_19189_0_1, [Score=161, Expect=5e-41]} {RNA1509_6346} {RNA1310_5254, RNA1509_6346} {RNA1509_6346, RNA815_4443}
72. MligTC455_44432 1115 23.23 Mlig455_015671, Mlig455_062480

Neo: -

Age: logFC(26M/2M)=0.247

F5 2.463 - 0.718 - 0.793 - 0.952

Mlig455_015671 {REF} {Length: 5764} {Pfam: F5/8 type C domain [PF00754.27, score=47.5]} {Human: ENSG00000198734, F5, coagulation factor V, [Score=64.3, Expect=2e-09]; ENSG00000185010, F8, coagulation factor VIII, [Score=62.8, Expect=6e-09]} {Mouse: ENSMUSG00000031196, F8, coagulation factor VIII, [Score=69.3, Expect=4e-11]} {Dmel: FBgn0053531, Ddr, Discoidin domain receptor, [Score=50.8, Expect=6e-06]} {Smed: dd_Smed_v6_15631_0_1, dd_Smed_v6_15631_0_1, [Score=87.8, Expect=3e-17]} {RNA1509_2035} {RNA1310_951.1, RNA1509_2035} {RNA1509_2035, RNA815_305}

Mlig455_062480 {REF} {Length: 6260} {Pfam: F5/8 type C domain [PF00754.27, score=47.5]} {Human: ENSG00000198734, F5, coagulation factor V, [Score=64.7, Expect=2e-09]; ENSG00000185010, F8, coagulation factor VIII, [Score=62.0, Expect=1e-08]} {Mouse: ENSMUSG00000031196, F8, coagulation factor VIII, [Score=68.2, Expect=9e-11]} {Dmel: FBgn0053531, Ddr, Discoidin domain receptor, [Score=53.5, Expect=1e-06]} {Smed: dd_Smed_v6_15631_0_1, dd_Smed_v6_15631_0_1, [Score=89.7, Expect=8e-18]} {RNA1509_2035, RNA1509_37215} {RNA1310_951.1, RNA1509_37215} {RNA1509_37215, RNA815_305}
73. MligTC455_30366 614 12.78 Mlig455_005372, Mlig455_005424, Mlig455_036242

Neo: -

Age: logFC(26M/2M)=-0.322

C20orf194 2.46 - - 0.739 0.763 - 0.958

Mlig455_005372 {REF} {Length: 2621} {Human: ENSG00000088854, C20orf194, chromosome 20 open reading frame 194, [Score=103, Expect=6e-22]} {Mouse: ENSMUSG00000027309, 4930402H24Rik, RIKEN cDNA 4930402H24 gene, [RH, Score=110, Expect=3e-24]} {Smed: dd_Smed_v6_10121_0_1, dd_Smed_v6_10121_0_1, [Score=89.7, Expect=3e-18]} {RNA1509_13613} {RNA1310_6491.1} {RNA815_2468}

Mlig455_005424 {REF} {Length: 829} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_13613} {RNA1310_1263.1} {RNA815_2468}

Mlig455_036242 {REF} {Length: 3746} {Human: ENSG00000088854, C20orf194, chromosome 20 open reading frame 194, [RH, Score=165, Expect=7e-41]} {Mouse: ENSMUSG00000027309, 4930402H24Rik, RIKEN cDNA 4930402H24 gene, [RH, Score=162, Expect=3e-40]} {Smed: dd_Smed_v6_10121_0_1, dd_Smed_v6_10121_0_1, [RH, Score=178, Expect=3e-45]} {RNA1509_13613} {RNA1310_6491.1, RNA1509_13613} {RNA1509_13613, RNA815_2468}
74. MligTC455_35895 102 2.12 Mlig455_063971

Neo: -

Age: -

RYK 2.459 - - 0.763 0.741 - 0.955 Mlig455_063971 {REF} {Length: 3496} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=209.4]; WIF domain [PF02019.20, score=109.7]; Protein kinase domain [PF00069.27, score=79.1]} {Human: ENSG00000163785, RYK, receptor-like tyrosine kinase, [Score=202, Expect=1e-55]} {Mouse: ENSMUSG00000032547, Ryk, receptor-like tyrosine kinase, [RH, Score=202, Expect=2e-55]} {Dmel: FBgn0015380, drl, derailed, [RH, Score=239, Expect=4e-69]} {Celegans: WBGene00003007, lin-18, Inactive tyrosine-protein kinase RYK, [Score=179, Expect=6e-48]} {Smed: dd_Smed_v6_12594_0_2, dd_Smed_v6_12594_0_2, [Score=201, Expect=3e-55]} {RNA1509_58811} {RNA1310_6671.2} {RNA815_41921}
75. MligTC455_08760 88 1.82 Mlig455_032303

Neo: -

Age: -

2.456 - - 0.704 0.786 - 0.966 Mlig455_032303 {REF} {Length: 746} {Pfam: WSC domain [PF01822.21, score=46.4]; PAN domain [PF00024.28, score=25.3]} {RNA1310_49278} {RNA815_40649}
76. MligTC455_19276 1694 35.28 Mlig455_057303

Neo: -

Age: Down-Down-Up

Region-specific R2: 5.711

Region-enriched R2: 6.117/0.00000
Region-enriched R3: 2.663/0.00058

2.453 0.727 - - 0.772 - 0.954 Mlig455_057303 {REF} {Length: 1196} {Pfam: TATA-binding related factor (TRF) of subunit 20 of Mediator complex [PF08612.13, score=80.6]} {Smed: dd_Smed_v6_9879_0_1, dd_Smed_v6_9879_0_1, [RH, Score=73.9, Expect=1e-15]} {RNA1509_58478} {RNA1310_35292} {RNA815_20171}
77. MligTC455_39418 105 2.19 Mlig455_060584

Neo: -

Age: logFC(26M/2M)=-0.365

2.452 - 0.760 0.719 - 0.973 - Mlig455_060584 {REF} {Length: 2959} {RNA1509_1853, RNA1509_19407} {RNA1310_3937, RNA1509_1853, RNA1509_19407} {RNA1509_1853, RNA1509_19407, RNA815_2591.1}
78. MligTC455_41028 108 2.26 Mlig455_033278

Neo: -

Age: -

2.449 - - 0.725 0.774 - 0.950 Mlig455_033278 {REF} {Length: 1134} {Pfam: PAN domain [PF00024.28, score=19.4]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=68.2, Expect=9e-14]} {RNA1310_31986} {RNA815_17816.2}
79. MligTC455_22688 18 0.37 Mlig455_030413

Neo: -

Age: -

GRIK3 2.444 - - 0.732 0.761 - 0.951 Mlig455_030413 {REF} {Length: 3851} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=76.0]; Ligand-gated ion channel [PF00060.28, score=51.9]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=45.7]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=158, Expect=1e-40]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=153, Expect=7e-39]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=149, Expect=7e-38]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=149, Expect=6e-38]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=148, Expect=2e-37]} {Dmel: FBgn0039916, Ekar, Eye-enriched kainate receptor, [Score=142, Expect=1e-35]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=132, Expect=1e-32]} {Smed: dd_Smed_v6_4267_0_3, dd_Smed_v6_4267_0_3, [Score=149, Expect=5e-38]} {RNA1310_20394.1} {RNA815_45848}
80. MligTC455_32560 474 9.88 Mlig455_005052

Neo: -

Age: -

2.443 - 0.721 - - 0.761 0.961 Mlig455_005052 {REF} {Length: 3173} {Smed: dd_Smed_v6_9637_0_1, dd_Smed_v6_9637_0_1, [Score=71.6, Expect=1e-12]} {RNA1509_2854} {RNA1310_3474} {RNA815_179}
81. MligTC455_38126 181 3.78 Mlig455_001217

Neo: -

Age: Down-Up-Down

MOK 2.442 - - - 0.759 0.704 0.979 Mlig455_001217 {REF} {Length: 3206} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=225.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=101.8]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=23.8]; RIO1 family [PF01163.24, score=20.1]; Kinase-like [PF14531.8, score=19.8]; Kinetochore Sim4 complex subunit FTA2 [PF13095.8, score=18.7]} {Human: ENSG00000080823, MOK, MOK protein kinase, [RH, Score=394, Expect=4e-133]} {Mouse: ENSMUSG00000056458, Mok, MOK protein kinase, [RH, Score=397, Expect=1e-134]} {Dmel: FBgn0259712, CG42366, [Score=259, Expect=5e-78]} {Celegans: WBGene00001121, dyf-5, Serine/threonine-protein kinase dyf-5, [Score=230, Expect=2e-69]} {Smed: dd_Smed_v6_15542_0_1, dd_Smed_v6_15542_0_1, [RH, Score=416, Expect=2e-141]} {RNA1509_23114, RNA1509_48468} {RNA1310_15433.1, RNA1509_23114, RNA1509_48468} {RNA1509_23114, RNA1509_48468, RNA815_13706}
82. MligTC455_45450 66 1.38 Mlig455_061622

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.869

ZIC4 2.441 - - 0.766 - 0.723 0.952 Mlig455_061622 {REF} {Length: 1709} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=49.3]; Zinc-finger double domain [PF13465.8, score=44.8]; Zic proteins zinc finger domain [PF18366.3, score=30.5]} {Human: ENSG00000174963, ZIC4, Zic family member 4, [Score=201, Expect=5e-62]; ENSG00000156925, ZIC3, Zic family member 3, [Score=197, Expect=3e-59]; ENSG00000043355, ZIC2, Zic family member 2, [Score=197, Expect=2e-58]; ENSG00000152977, ZIC1, Zic family member 1, [Score=196, Expect=8e-59]; ENSG00000139800, ZIC5, Zic family member 5, [Score=194, Expect=1e-56]} {Mouse: ENSMUSG00000041703, Zic5, zinc finger protein of the cerebellum 5, [Score=199, Expect=9e-59]; ENSMUSG00000036972, Zic4, zinc finger protein of the cerebellum 4, [Score=197, Expect=9e-61]; ENSMUSG00000067860, Zic3, zinc finger protein of the cerebellum 3, [Score=197, Expect=2e-59]; ENSMUSG00000032368, Zic1, zinc finger protein of the cerebellum 1, [Score=196, Expect=5e-59]; ENSMUSG00000061524, Zic2, zinc finger protein of the cerebellum 2, [Score=196, Expect=1e-58]} {Dmel: FBgn0003002, opa, odd paired, [Score=194, Expect=5e-57]} {Celegans: WBGene00004335, ref-2, REgulator of Fusion, [Score=171, Expect=3e-51]} {Smed: dd_Smed_v6_15531_0_1, dd_Smed_v6_15531_0_1, [Score=214, Expect=4e-66]} {RNA1310_23362} {RNA815_19034}
83. MligTC455_35943 122 2.55 Mlig455_062123

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.634

FEZF2 2.439 - - - 0.726 0.758 0.955 Mlig455_062123 {REF} {Length: 3163} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=87.7]; Zinc-finger double domain [PF13465.8, score=71.3]; C2H2-type zinc finger [PF13894.8, score=56.0]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=25.4]; Transcription factor IIA, alpha/beta subunit [PF03153.15, score=23.1]; C2H2-type zinc finger [PF13912.8, score=21.6]} {Human: ENSG00000153266, FEZF2, FEZ family zinc finger 2, [RH, Score=337, Expect=3e-107]; ENSG00000128610, FEZF1, FEZ family zinc finger 1, [RH, Score=330, Expect=6e-105]} {Mouse: ENSMUSG00000021743, Fezf2, Fez family zinc finger 2, [RH, Score=341, Expect=7e-109]; ENSMUSG00000029697, Fezf1, Fez family zinc finger 1, [RH, Score=330, Expect=1e-104]} {Dmel: FBgn0031375, erm, earmuff, [RH, Score=343, Expect=2e-107]} {Celegans: WBGene00012639, fezf-1, FEZ Family zinc finger protein, [RH, Score=293, Expect=5e-94]} {Smed: dd_Smed_v6_26394_0_1, dd_Smed_v6_26394_0_1, [RH, Score=287, Expect=9e-92]} {RNA1310_14572} {RNA815_32467}
84. MligTC455_17412 44 0.91 Mlig455_069737

Neo: -

Age: -

Region-enriched R2: 5.062/0.00923

2.436 - - - 0.784 0.701 0.951 Mlig455_069737 {REF} {Length: 1628} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=42.8]} {Smed: dd_Smed_v6_31564_0_1, dd_Smed_v6_31564_0_1, [Score=72.8, Expect=3e-14]} {RNA1310_45758} {RNA815_42912}
85. MligTC455_19277 1013 21.11 Mlig455_059600

Neo: -

Age: -

Region-specific R2: 4.883

Region-enriched R2: 5.766/0.00000
Region-enriched R3: 2.030/0.00976

2.435 0.783 - - - 0.700 0.952 Mlig455_059600 {REF} {Length: 827} {NoTransDecoderORF} {RNA1509_43907} {RNA1310_81348}
86. MligTC455_42839 29 0.61 Mlig455_003852

Neo: -

Age: -

2.435 - - 0.743 0.741 - 0.951 Mlig455_003852 {REF} {Length: 1047} {RNA1509_48973} {RNA1310_36721} {RNA815_36286}
87. MligTC455_31841 36 0.75 Mlig455_015886

Neo: -

Age: Down-Up-Down

2.434 - - 0.749 - 0.727 0.958 Mlig455_015886 {REF} {Length: 4290} {Pfam: Variant SH3 domain [PF14604.8, score=21.1]; SH3 domain [PF00018.30, score=19.3]} {RNA1509_25886} {RNA1310_33360} {RNA815_17069.1}
88. MligTC455_27988 1036 21.59 Mlig455_006811, Mlig455_055192

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.311

CFAP54 2.433 - - 0.767 0.713 - 0.953

Mlig455_006811 {REF} {Length: 11171} {Pfam: Cilia- and flagella-associated protein 54 [PF14858.8, score=586.0]} {Human: ENSG00000188596, CFAP54, cilia and flagella associated protein 54, [RH, Score=1136, Expect=0.0]} {Mouse: ENSMUSG00000020014, Cfap54, cilia and flagella associated protein 54, [Score=1144, Expect=0.0]} {Smed: dd_Smed_v6_9860_0_1, dd_Smed_v6_9860_0_1, [Score=347, Expect=2e-95]} {RNA1509_2904} {RNA1310_96.1} {RNA815_135}

Mlig455_055192 {REF} {Length: 10890} {Pfam: Cilia- and flagella-associated protein 54 [PF14858.8, score=578.4]} {Human: ENSG00000188596, CFAP54, cilia and flagella associated protein 54, [Score=1112, Expect=0.0]} {Mouse: ENSMUSG00000020014, Cfap54, cilia and flagella associated protein 54, [RH, Score=1114, Expect=0.0]} {Smed: dd_Smed_v6_9860_0_2, dd_Smed_v6_9860_0_2, [RH, Score=519, Expect=1e-147]} {RNA1509_2904} {RNA1310_96.1} {RNA815_135}
89. MligTC455_35381 14 0.29 Mlig455_016857

Neo: -

Age: logFC(26M/2M)=-1.315

HMCN1 2.416 - - 0.737 - 0.728 0.951 Mlig455_016857 {REF} {Length: 4332} {Pfam: Fibronectin type II domain [PF00040.21, score=44.0]} {Human: ENSG00000143341, HMCN1, hemicentin 1, [Score=106, Expect=3e-22]} {Mouse: ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=112, Expect=2e-24]} {Dmel: FBgn0284221, Sema5c, Semaphorin 5c, [Score=65.9, Expect=2e-10]} {Celegans: WBGene00011880, T21B6.3, [Score=80.9, Expect=4e-15]} {Smed: dd_Smed_v6_1161_0_1, dd_Smed_v6_1161_0_1, [Score=105, Expect=1e-22]} {RNA1509_59017} {RNA1310_52334} {RNA815_20741}
90. MligTC455_47905 56 1.16 Mlig455_037694

Neo: -

Age: -

2.411 - - - 0.731 0.728 0.952 Mlig455_037694 {REF} {Length: 2503} {RNA1310_36768.1} {RNA815_27683}
91. MligTC455_41540 190 3.96 Mlig455_060056

Neo: -

Age: -

Region-enriched R2: 6.605/0.00196

GLUL 2.406 0.747 - - 0.708 - 0.951 Mlig455_060056 {REF} {Length: 1355} {Pfam: Glutamine synthetase, catalytic domain [PF00120.26, score=57.3]; Glutamine synthetase, beta-Grasp domain [PF03951.21, score=47.5]} {Human: ENSG00000135821, GLUL, glutamate-ammonia ligase, [RH, Score=511, Expect=1e-180]} {Mouse: ENSMUSG00000026473, Glul, glutamate-ammonia ligase (glutamine synthetase), [RH, Score=511, Expect=0.0]} {Dmel: FBgn0001145, Gs2, Glutamine synthetase 2, [RH, Score=511, Expect=0.0]} {Celegans: WBGene00001604, gln-3, Glutamine synthetase, [RH, Score=515, Expect=0.0]} {Smed: dd_Smed_v6_896_0_1, dd_Smed_v6_896_0_1, [RH, Score=545, Expect=0.0]} {RNA1509_47000} {RNA1310_22329.2} {RNA815_4116.6}
92. MligTC455_34498 36 0.75 Mlig455_029862

Neo: -

Age: -

NPLOC4 2.388 - - - 0.703 0.728 0.957 Mlig455_029862 {REF} {Length: 1491} {TRANSSPLICED} {Pfam: NPL4 family, putative zinc binding region [PF05020.17, score=77.9]} {Human: ENSG00000182446, NPLOC4, NPL4 homolog, ubiquitin recognition factor, [Score=98.2, Expect=1e-21]} {Mouse: ENSMUSG00000039703, Nploc4, NPL4 homolog, ubiquitin recognition factor, [Score=102, Expect=3e-23]} {Celegans: WBGene00019121, npl-4.2, NPL (Yeast Nuclear Protein Localization) homolog, [Score=54.3, Expect=6e-08]} {Smed: dd_Smed_v6_5277_0_1, dd_Smed_v6_5277_0_1, [Score=102, Expect=1e-23]} {RNA1509_6797} {RNA1310_13992} {RNA815_5567}
93. MligTC455_40325 103 2.15 Mlig455_013035

Neo: -

Age: -

2.386 - - 0.729 0.704 - 0.953 Mlig455_013035 {REF} {Length: 653} {RNA1509_20946} {RNA1310_44606} {RNA815_35640}
94. MligTC455_26253 375 7.81 Mlig455_009976

Neo: -

Age: -

FZD5 2.383 - - 0.710 - 0.721 0.952 Mlig455_009976 {REF} {Length: 4082} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=407.2]; Fz domain [PF01392.24, score=99.7]} {Human: ENSG00000163251, FZD5, frizzled class receptor 5, [RH, Score=605, Expect=0.0]} {Mouse: ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [RH, Score=607, Expect=0.0]} {Dmel: FBgn0016797, fz2, frizzled 2, [RH, Score=402, Expect=2e-130]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [RH, Score=417, Expect=8e-139]} {Smed: dd_Smed_v6_11823_0_1, dd_Smed_v6_11823_0_1, [RH, Score=551, Expect=0.0]} {RNA1509_25697, RNA1509_59712} {RNA1310_9946, RNA1509_25697} {RNA1509_25697, RNA815_7287}
95. MligTC455_44810 226 4.72 Mlig455_013293, Mlig455_035940, Mlig455_058406, Mlig455_058409

Neo: -

Age: -

Region-specific R2: 6.204

Region-enriched R2: 5.509/0.00501

2.375 0.705 - - 0.715 - 0.955

Mlig455_013293 {REF} {Length: 1362} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=56.6, Expect=2e-09]} {RNA1310_28961.1} {RNA815_27532}

Mlig455_035940 {REF} {Length: 1652} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=55.8, Expect=3e-09]} {RNA1310_28961.1} {RNA815_27532}

Mlig455_058406 {REF} {Length: 991} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=55.8, Expect=4e-09]} {RNA1310_28961.1} {RNA815_27532}

Mlig455_058409 {REF} {Length: 1311} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=55.8, Expect=3e-09]} {RNA1310_28961.1} {RNA815_27532}
96. MligTC455_19455 23 0.48 Mlig455_059587

Neo: -

Age: Up-Down-Down

2.372 - - 0.706 - 0.712 0.954 Mlig455_059587 {REF} {Length: 1356} {Pfam: FAM216B protein family [PF15107.8, score=21.6]} {RNA1310_31687} {RNA815_40824}
97. MligTC455_44809 88 1.83 Mlig455_035938

Neo: -

Age: -

2.37 0.711 - - 0.703 - 0.956 Mlig455_035938 {REF} {Length: 1369} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=55.8, Expect=3e-09]} {RNA1310_28961.1} {RNA815_27532}
98. MligTC455_25410 47 0.97 Mlig455_026185

Neo: -

Age: Up-Down-Down

Region-enriched R2: 8.036/0.00469
Region-enriched R6: 6.422/0.01487

1.912 - - - - 0.962 0.950 Mlig455_026185 {REF} {Length: 3002} {Pfam: Variant SH3 domain [PF07653.19, score=19.6]; Growth-arrest specific micro-tubule binding [PF13851.8, score=19.3]} {Mouse: ENSMUSG00000034156, Tspoap1, TSPO associated protein 1, [Score=54.7, Expect=6e-07]} {Smed: dd_Smed_v6_14584_0_1, dd_Smed_v6_14584_0_1, [Score=140, Expect=7e-35]} {RNA1509_45271} {RNA1310_5741} {RNA815_46868}
99. MligTC455_50660 81 1.7 Mlig455_019591

Neo: -

Age: -

SLC9B2 1.867 - - - - 0.907 0.960 Mlig455_019591 {REF} {Length: 2686} {Pfam: Sodium/hydrogen exchanger family [PF00999.23, score=30.0]} {Human: ENSG00000164038, SLC9B2, solute carrier family 9 member B2, [Score=124, Expect=1e-31]} {Mouse: ENSMUSG00000037994, Slc9b2, solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2, [Score=116, Expect=1e-28]; ENSMUSG00000050150, Slc9b1, solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1, [Score=112, Expect=2e-27]} {Dmel: FBgn0263390, Nha2, Na[+]/H[+] hydrogen antiporter 2, [Score=113, Expect=1e-27]} {Celegans: WBGene00009618, F41E7.2, [Score=70.9, Expect=2e-13]} {Smed: dd_Smed_v6_7736_0_1, dd_Smed_v6_7736_0_1, [Score=148, Expect=1e-43]} {RNA1509_34461} {RNA1310_39553.1} {RNA815_32589}
100. MligTC455_53239 733 15.27 Mlig455_025537

Neo: -

Age: -

Region-specific R2: 4.434

Region-enriched R2: 3.108/0.00000

1.863 0.961 - - - - 0.902 Mlig455_025537 {REF} {Length: 964} {Pfam: Low-density lipoprotein receptor domain class A [PF00057.20, score=28.0]} {Dmel: FBgn0051221, CG31221, [RH, Score=70.9, Expect=5e-15]} {Celegans: WBGene00010290, F58H1.7, [Score=63.9, Expect=8e-13]} {Smed: dd_Smed_v6_5576_0_1, dd_Smed_v6_5576_0_1, [RH, Score=168, Expect=2e-53]} {RNA1509_58542} {RNA1310_40950} {RNA815_19778.1}

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