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Results for MligTC455_22762

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_22762 328 6.84 Mlig455_036232

Neo: -

Age: logFC(26M/2M)=0.467

ELOVL4 Mlig455_036232 {REF} {Length: 1770} {TRANSSPLICED} {Pfam: GNS1/SUR4 family [PF01151.20, score=205.6]} {Human: ENSG00000118402, ELOVL4, ELOVL fatty acid elongase 4, [RH, Score=308, Expect=2e-104]} {Mouse: ENSMUSG00000032262, Elovl4, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4, [RH, Score=304, Expect=5e-103]} {Dmel: FBgn0052072, Elo68alpha, Elongase 68alpha, [RH, Score=214, Expect=2e-68]} {Celegans: WBGene00001245, elo-7, Elongation of very long chain fatty acids protein, [Score=81.3, Expect=1e-17]} {Smed: dd_Smed_v6_7835_0_1, dd_Smed_v6_7835_0_1, [Score=308, Expect=2e-105]} {RNA1509_11261} {RNA1310_21427.1} {RNA815_6649.1}

Cumulative graph for MligTC455_22762

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.618 3.295 0.70768 1.00000
RegionR2 0.957 3.295 0.21484 0.58091
RegionR3 -0.177 3.295 0.79013 1.00000
RegionR4 0.357 3.295 0.62963 0.93810
RegionR5 -0.118 3.295 0.84798 1.00000
RegionR6 -0.366 3.295 0.59366 1.00000
RegionR7 0.12 3.295 0.88351 1.00000
RegionR8 -1.39 3.295 0.29020 0.91801

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -6.378 3.295 0.19506 0.93368
RegenerationR2 1.571 3.295 0.00564 0.11917
RegenerationR3 0.637 3.295 0.38020 0.79061
RegenerationR4 0.5 3.295 0.49111 0.86521
RegenerationR5 0.541 3.295 0.41341 0.80770
RegenerationR6 -0.171 3.295 0.82363 0.98837
RegenerationBL 0.482 3.295 0.59543 0.94396
RegenerationTP -0.273 3.295 0.81784 1.00000


Genes with expression patterns similar to MligTC455_22762

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_22762 328 6.84 Mlig455_036232

Neo: -

Age: logFC(26M/2M)=0.467

ELOVL4 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_036232 {REF} {Length: 1770} {TRANSSPLICED} {Pfam: GNS1/SUR4 family [PF01151.20, score=205.6]} {Human: ENSG00000118402, ELOVL4, ELOVL fatty acid elongase 4, [RH, Score=308, Expect=2e-104]} {Mouse: ENSMUSG00000032262, Elovl4, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4, [RH, Score=304, Expect=5e-103]} {Dmel: FBgn0052072, Elo68alpha, Elongase 68alpha, [RH, Score=214, Expect=2e-68]} {Celegans: WBGene00001245, elo-7, Elongation of very long chain fatty acids protein, [Score=81.3, Expect=1e-17]} {Smed: dd_Smed_v6_7835_0_1, dd_Smed_v6_7835_0_1, [Score=308, Expect=2e-105]} {RNA1509_11261} {RNA1310_21427.1} {RNA815_6649.1}
2. MligTC455_22761 288 6.01 Mlig455_005521

Neo: -

Age: -

ELOVL4 5.67 0.953 0.776 0.991 0.984 0.968 0.998 Mlig455_005521 {REF} {Length: 1592} {TRANSSPLICED} {Pfam: GNS1/SUR4 family [PF01151.20, score=138.3]} {Human: ENSG00000118402, ELOVL4, ELOVL fatty acid elongase 4, [Score=220, Expect=1e-70]} {Mouse: ENSMUSG00000032262, Elovl4, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4, [Score=216, Expect=1e-69]} {Dmel: FBgn0052072, Elo68alpha, Elongase 68alpha, [Score=145, Expect=2e-42]} {Celegans: WBGene00001244, elo-6, Elongation of very long chain fatty acids protein 6, [Score=52.8, Expect=4e-08]} {Smed: dd_Smed_v6_7835_0_1, dd_Smed_v6_7835_0_1, [Score=215, Expect=7e-70]} {RNA1509_11261} {RNA1310_42181} {RNA815_6649.1}
3. MligTC455_13102 65 1.35 Mlig455_056246

Neo: -

Age: Up-Down-Down

Region-enriched R2: 6.206/0.00027

NWD2 4.429 0.813 - 0.860 0.945 0.844 0.967 Mlig455_056246 {REF} {Length: 8104} {Pfam: NACHT domain [PF05729.14, score=51.2]; AAA ATPase domain [PF13191.8, score=36.8]; Domain of unknown function (DUF4062) [PF13271.8, score=36.5]; ATPase domain predominantly from Archaea [PF01637.20, score=23.7]; AAA domain [PF13401.8, score=20.6]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=451, Expect=2e-130]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [RH, Score=436, Expect=2e-125]} {Dmel: FBgn0038397, CG10185, [RH, Score=980, Expect=0.0]} {Celegans: WBGene00020254, T05C3.2, [RH, Score=925, Expect=0.0]} {Smed: dd_Smed_v6_11085_0_1, dd_Smed_v6_11085_0_1, [Score=344, Expect=9e-96]} {RNA1509_20730} {RNA1310_1147} {RNA815_11922}
4. MligTC455_10215 54 1.12 Mlig455_012202, Mlig455_028799

Neo: -

Age: logFC(26M/2M)=-0.429

PCDH9, PCDHB16 4.338 0.842 - 0.755 0.952 0.810 0.979

Mlig455_012202 {REF} {Length: 2809} {Pfam: Cadherin domain [PF00028.19, score=133.3]; Cadherin-like [PF16184.7, score=19.8]} {Human: ENSG00000272674, PCDHB16, protocadherin beta 16, [Score=123, Expect=4e-28]; ENSG00000113211, PCDHB6, protocadherin beta 6, [Score=122, Expect=5e-28]; ENSG00000250120, PCDHA10, protocadherin alpha 10, [Score=122, Expect=1e-27]; ENSG00000204970, PCDHA1, protocadherin alpha 1, [Score=122, Expect=1e-27]; ENSG00000113212, PCDHB7, protocadherin beta 7, [Score=121, Expect=1e-27]; ENSG00000177839, PCDHB9, protocadherin beta 9, [Score=119, Expect=4e-27]; ENSG00000204963, PCDHA7, protocadherin alpha 7, [Score=119, Expect=6e-27]; ENSG00000243232, PCDHAC2, protocadherin alpha subfamily C, 2, [Score=119, Expect=8e-27]; ENSG00000204961, PCDHA9, protocadherin alpha 9, [Score=118, Expect=1e-26]; ENSG00000099715, PCDH11Y, protocadherin 11 Y-linked, [Score=117, Expect=4e-26]; ENSG00000138650, PCDH10, protocadherin 10, [Score=117, Expect=3e-26]} {Mouse: ENSMUSG00000103442, Pcdha1, protocadherin alpha 1, [Score=127, Expect=2e-29]; ENSMUSG00000102222, Pcdhga10, protocadherin gamma subfamily A, 10, [Score=127, Expect=1e-29]; ENSMUSG00000036862, Dchs1, dachsous cadherin related 1, [Score=126, Expect=5e-29]; ENSMUSG00000102692, Dchs2, dachsous cadherin related 2, [Score=125, Expect=2e-28]; ENSMUSG00000007440, Pcdha11, protocadherin alpha 11, [Score=124, Expect=1e-28]} {Dmel: FBgn0261574, kug, kugelei, [Score=117, Expect=3e-26]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=96.3, Expect=6e-20]} {Smed: dd_Smed_v6_16566_0_2, dd_Smed_v6_16566_0_2, [Score=214, Expect=5e-58]} {RNA1509_32459} {RNA1310_2760.2} {RNA815_22195}

Mlig455_028799 {REF} {Length: 4449} {Pfam: Cadherin domain [PF00028.19, score=242.6]; Cadherin-like [PF16184.7, score=24.0]} {Human: ENSG00000184226, PCDH9, protocadherin 9, [Score=234, Expect=1e-62]} {Mouse: ENSMUSG00000055421, Pcdh9, protocadherin 9, [Score=234, Expect=1e-62]; ENSMUSG00000034755, Pcdh11x, protocadherin 11 X-linked, [Score=226, Expect=5e-60]} {Dmel: FBgn0001075, ft, fat, [Score=196, Expect=2e-50]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=161, Expect=8e-40]} {Smed: dd_Smed_v6_16566_0_1, dd_Smed_v6_16566_0_1, [RH, Score=349, Expect=1e-103]} {RNA1509_32459} {RNA1310_2760.1, RNA1509_32459} {RNA1509_32459, RNA815_6515}
5. MligTC455_13905 34 0.71 Mlig455_023395

Neo: -

Age: -

4.308 0.781 - 0.873 0.934 0.757 0.963 Mlig455_023395 {REF} {Length: 1110} {Smed: dd_Smed_v6_12856_0_1, dd_Smed_v6_12856_0_1, [Score=47.0, Expect=2e-06]} {RNA1509_18233} {RNA1310_51675} {RNA815_25040}
6. MligTC455_40228 146 3.03 Mlig455_010654, Mlig455_010753

Neo: -

Age: logFC(26M/2M)=0.372

Region-enriched R2: 5.064/0.02014

KY 4.27 0.849 - 0.822 0.968 0.737 0.894

Mlig455_010654 {REF} {Length: 3057} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=103, Expect=6e-22]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=113, Expect=2e-25]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=373, Expect=6e-115]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [RH, Score=347, Expect=3e-106]} {Smed: dd_Smed_v6_1846_0_1, dd_Smed_v6_1846_0_1, [Score=207, Expect=1e-55]} {RNA1509_35609} {RNA1310_6947.1} {RNA815_20684}

Mlig455_010753 {REF} {Length: 3328} {Pfam: LIM domain [PF00412.24, score=33.6]} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=104, Expect=3e-22]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=114, Expect=2e-25]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=376, Expect=1e-115]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [RH, Score=353, Expect=4e-108]} {Smed: dd_Smed_v6_1846_0_1, dd_Smed_v6_1846_0_1, [Score=207, Expect=2e-55]} {RNA1509_35609} {RNA1310_6947.1, RNA1509_35609} {RNA1509_35609, RNA815_20684}
7. MligTC455_12180 107 2.23 Mlig455_038554, Mlig455_052202, Mlig455_053449

Neo: -

Age: logFC(26M/2M)=-0.655

Region-enriched R2: 5.717/0.01573

CNGA3 4.227 0.753 - 0.941 0.743 0.818 0.972

Mlig455_038554 {REF} {Length: 2866} {Pfam: C-terminal leucine zipper domain of cyclic nucleotide-gated channels [PF16526.7, score=75.9]; Cyclic nucleotide-binding domain [PF00027.31, score=69.1]; Ion transport protein [PF00520.33, score=68.6]} {Human: ENSG00000144191, CNGA3, cyclic nucleotide gated channel alpha 3, [RH, Score=650, Expect=0.0]} {Mouse: ENSMUSG00000026114, Cnga3, cyclic nucleotide gated channel alpha 3, [RH, Score=644, Expect=0.0]} {Dmel: FBgn0261612, CngA, Cyclic nucleotide-gated ion channel subunit A, [RH, Score=607, Expect=0.0]} {Celegans: WBGene00006526, tax-4, Cyclic nucleotide-gated cation channel, [RH, Score=563, Expect=0.0]} {Smed: dd_Smed_v6_22398_0_1, dd_Smed_v6_22398_0_1, [RH, Score=669, Expect=0.0]} {RNA1310_22950} {RNA815_16119}

Mlig455_052202 {REF} {Length: 3203} {Pfam: C-terminal leucine zipper domain of cyclic nucleotide-gated channels [PF16526.7, score=76.1]; Cyclic nucleotide-binding domain [PF00027.31, score=69.1]; Ion transport protein [PF00520.33, score=68.2]} {Human: ENSG00000144191, CNGA3, cyclic nucleotide gated channel alpha 3, [RH, Score=650, Expect=0.0]} {Mouse: ENSMUSG00000026114, Cnga3, cyclic nucleotide gated channel alpha 3, [RH, Score=644, Expect=0.0]} {Dmel: FBgn0261612, CngA, Cyclic nucleotide-gated ion channel subunit A, [RH, Score=605, Expect=0.0]} {Celegans: WBGene00006526, tax-4, Cyclic nucleotide-gated cation channel, [RH, Score=563, Expect=0.0]} {Smed: dd_Smed_v6_22398_0_1, dd_Smed_v6_22398_0_1, [RH, Score=667, Expect=0.0]} {RNA1310_22950} {RNA815_16119}

Mlig455_053449 {REF} {Length: 991} {Pfam: C-terminal leucine zipper domain of cyclic nucleotide-gated channels [PF16526.7, score=79.9]; Cyclic nucleotide-binding domain [PF00027.31, score=29.1]} {Human: ENSG00000144191, CNGA3, cyclic nucleotide gated channel alpha 3, [Score=171, Expect=7e-50]} {Mouse: ENSMUSG00000026114, Cnga3, cyclic nucleotide gated channel alpha 3, [Score=161, Expect=2e-46]; ENSMUSG00000067220, Cnga1, cyclic nucleotide gated channel alpha 1, [Score=155, Expect=4e-44]} {Dmel: FBgn0261612, CngA, Cyclic nucleotide-gated ion channel subunit A, [Score=148, Expect=1e-41]} {Celegans: WBGene00006526, tax-4, Cyclic nucleotide-gated cation channel, [Score=149, Expect=3e-42]} {Smed: dd_Smed_v6_22398_0_1, dd_Smed_v6_22398_0_1, [Score=155, Expect=8e-45]} {RNA1310_61700} {RNA815_16119}
8. MligTC455_15492 69 1.44 Mlig455_022488

Neo: -

Age: Down-Up-Up

3.757 - - 0.941 0.932 0.900 0.984 Mlig455_022488 {REF} {Length: 1351} {RNA1310_26051} {RNA815_10966}
9. MligTC455_13963 31 0.64 Mlig455_052027

Neo: -

Age: Down-Up-Down

3.709 - - 0.827 0.940 0.962 0.980 Mlig455_052027 {REF} {Length: 1717} {RNA1509_48973} {RNA1310_34931} {RNA815_59614}
10. MligTC455_40325 103 2.15 Mlig455_013035

Neo: -

Age: -

3.679 - - 0.875 0.927 0.896 0.981 Mlig455_013035 {REF} {Length: 653} {RNA1509_20946} {RNA1310_44606} {RNA815_35640}
11. MligTC455_43741 196 4.08 Mlig455_018088

Neo: -

Age: Down-Up-Down

PTBP1 3.679 - - 0.941 0.932 0.831 0.975 Mlig455_018088 {REF} {Length: 2775} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF13893.8, score=116.9]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=52.7]; Occluded RNA-recognition motif [PF16842.7, score=26.8]} {Human: ENSG00000011304, PTBP1, polypyrimidine tract binding protein 1, [Score=258, Expect=8e-80]; ENSG00000117569, PTBP2, polypyrimidine tract binding protein 2, [Score=258, Expect=1e-80]; ENSG00000119314, PTBP3, polypyrimidine tract binding protein 3, [Score=248, Expect=1e-76]} {Mouse: ENSMUSG00000028134, Ptbp2, polypyrimidine tract binding protein 2, [Score=258, Expect=7e-81]; ENSMUSG00000006498, Ptbp1, polypyrimidine tract binding protein 1, [Score=251, Expect=1e-78]; ENSMUSG00000028382, Ptbp3, polypyrimidine tract binding protein 3, [Score=248, Expect=1e-77]} {Dmel: FBgn0011224, heph, hephaestus, [Score=249, Expect=7e-78]} {Celegans: WBGene00004207, ptb-1, PTB (HnRNP) homolog; Putative RNA-binding protein PTB-1b, [Score=234, Expect=1e-72]} {Smed: dd_Smed_v6_1868_0_1, dd_Smed_v6_1868_0_1, [Score=214, Expect=4e-64]} {RNA1509_36451} {RNA1310_3345} {RNA815_23519}
12. MligTC455_03841 920 19.16 Mlig455_018790, Mlig455_048140

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.474

Region-enriched R2: 5.915/0.00081

NKX2-1, NKX2-4 3.657 - - 0.951 0.894 0.942 0.870

Mlig455_018790 {REF} {Length: 2203} {Pfam: Homeodomain [PF00046.31, score=72.7]} {Human: ENSG00000136352, NKX2-1, NK2 homeobox 1, [RH, Score=145, Expect=2e-39]; ENSG00000125816, NKX2-4, NK2 homeobox 4, [RH, Score=145, Expect=2e-39]} {Mouse: ENSMUSG00000001496, Nkx2-1, NK2 homeobox 1, [RH, Score=145, Expect=2e-39]} {Dmel: FBgn0028993, scro, scarecrow, [RH, Score=166, Expect=8e-47]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [RH, Score=134, Expect=2e-36]} {Smed: dd_Smed_v6_6729_0_1, dd_Smed_v6_6729_0_1, [RH, Score=191, Expect=1e-57]} {RNA1509_12761} {RNA1310_13401} {RNA815_21584}

Mlig455_048140 {REF} {Length: 2218} {Pfam: Homeodomain [PF00046.31, score=72.5]} {Human: ENSG00000125816, NKX2-4, NK2 homeobox 4, [RH, Score=145, Expect=3e-39]; ENSG00000136352, NKX2-1, NK2 homeobox 1, [RH, Score=145, Expect=7e-39]} {Mouse: ENSMUSG00000001496, Nkx2-1, NK2 homeobox 1, [RH, Score=144, Expect=6e-39]} {Dmel: FBgn0028993, scro, scarecrow, [RH, Score=166, Expect=2e-46]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [RH, Score=136, Expect=1e-36]} {Smed: dd_Smed_v6_6729_0_1, dd_Smed_v6_6729_0_1, [RH, Score=193, Expect=1e-57]} {RNA1509_12761} {RNA1310_13401, RNA1509_12761} {RNA1509_12761, RNA815_21584}
13. MligTC455_46880 44 0.91 Mlig455_046271

Neo: -

Age: -

IAH1 3.657 - - 0.837 0.947 0.907 0.966 Mlig455_046271 {REF} {Length: 1061} {Pfam: GDSL-like Lipase/Acylhydrolase family [PF13472.8, score=75.8]; GDSL-like Lipase/Acylhydrolase [PF00657.24, score=32.0]} {Human: ENSG00000134330, IAH1, isoamyl acetate hydrolyzing esterase 1 (putative), [Score=138, Expect=2e-39]} {Mouse: ENSMUSG00000062054, Iah1, isoamyl acetate-hydrolyzing esterase 1 homolog, [Score=121, Expect=4e-33]} {Smed: dd_Smed_v6_6241_0_1, dd_Smed_v6_6241_0_1, [Score=111, Expect=8e-30]} {RNA1310_130726}
14. MligTC455_16415 197 4.1 Mlig455_000401

Neo: -

Age: -

Region-enriched R2: 4.276/0.00982

ROR1 3.636 - - 0.784 0.920 0.947 0.985 Mlig455_000401 {REF} {Length: 3780} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=233.3]; Protein kinase domain [PF00069.27, score=85.9]; Immunoglobulin I-set domain [PF07679.18, score=49.4]; Immunoglobulin domain [PF13927.8, score=46.6]; Immunoglobulin domain [PF00047.27, score=31.9]; Immunoglobulin domain [PF13895.8, score=30.0]; Fz domain [PF01392.24, score=27.6]; Kringle domain [PF00051.20, score=22.3]; Immunoglobulin V-set domain [PF07686.19, score=19.5]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [RH, Score=390, Expect=1e-119]; ENSG00000169071, ROR2, receptor tyrosine kinase like orphan receptor 2, [RH, Score=379, Expect=1e-115]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [RH, Score=386, Expect=1e-118]; ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [RH, Score=377, Expect=4e-115]} {Dmel: FBgn0010407, Ror, [Score=286, Expect=3e-84]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=285, Expect=4e-82]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [RH, Score=439, Expect=2e-139]} {RNA1509_35395} {RNA1310_13558, RNA1509_35395} {RNA1509_35395, RNA815_27446}
15. MligTC455_22760 1202 25.04 Mlig455_005448

Neo: -

Age: -

ELOVL4 3.634 - - 0.834 0.880 0.941 0.979 Mlig455_005448 {REF} {Length: 1604} {TRANSSPLICED} {Pfam: GNS1/SUR4 family [PF01151.20, score=208.1]} {Human: ENSG00000118402, ELOVL4, ELOVL fatty acid elongase 4, [Score=284, Expect=2e-95]} {Mouse: ENSMUSG00000032262, Elovl4, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4, [Score=281, Expect=7e-95]} {Dmel: FBgn0052072, Elo68alpha, Elongase 68alpha, [Score=204, Expect=3e-65]} {Celegans: WBGene00001244, elo-6, Elongation of very long chain fatty acids protein 6, [Score=81.6, Expect=4e-18]} {Smed: dd_Smed_v6_7835_0_1, dd_Smed_v6_7835_0_1, [Score=286, Expect=2e-97]} {RNA1509_11261} {RNA1310_21427.2} {RNA815_6649.1}
16. MligTC455_31853 516 10.74 Mlig455_014495, Mlig455_014514, Mlig455_054434

Neo: -

Age: -

3.631 - - 0.858 0.947 0.967 0.859

Mlig455_014495 {REF} {Length: 3100} {RNA1509_20117} {RNA1310_5956.1, RNA1509_20117} {RNA1509_20117, RNA815_18508}

Mlig455_014514 {REF} {Length: 3051} {Smed: dd_Smed_v6_3795_0_2, dd_Smed_v6_3795_0_2, [RH, Score=89.7, Expect=2e-19]} {RNA1509_20117} {RNA1310_5956.1} {RNA815_18508}

Mlig455_054434 {REF} {Length: 4026} {Pfam: Late embryogenesis abundant protein [PF03242.15, score=21.0]} {Smed: dd_Smed_v6_3795_0_2, dd_Smed_v6_3795_0_2, [RH, Score=89.4, Expect=2e-20]} {RNA1509_20117} {RNA1310_8165} {RNA815_23492}
17. MligTC455_39481 461 9.6 Mlig455_056703, Mlig455_060318

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.222

ANGPTL1 3.606 - - 0.787 0.922 0.913 0.984

Mlig455_056703 {REF} {Length: 1114} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=79.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=89.4, Expect=1e-19]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=85.1, Expect=3e-18]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=91.3, Expect=2e-20]} {Dmel: FBgn0033312, CG8642, [Score=82.4, Expect=1e-17]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=76.3, Expect=1e-15]} {RNA1310_31288} {RNA815_20497.1}

Mlig455_060318 {REF} {Length: 1175} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=112.7]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=106, Expect=2e-25]; ENSG00000171819, ANGPTL7, angiopoietin like 7, [Score=105, Expect=6e-26]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=109, Expect=1e-26]} {Dmel: FBgn0034160, CG5550, [Score=96.3, Expect=2e-23]} {Celegans: WBGene00016769, C49C8.5, [Score=47.0, Expect=9e-06]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=88.2, Expect=2e-19]} {RNA1310_31288} {RNA815_20497.1}
18. MligTC455_30618 652 13.59 Mlig455_031172

Neo: -

Age: logFC(26M/2M)=-0.520

ITPR2 3.605 - - 0.889 0.971 0.851 0.894 Mlig455_031172 {REF} {Length: 9583} {Pfam: RIH domain [PF01365.23, score=93.8]; Inositol 1,4,5-trisphosphate/ryanodine receptor [PF08709.13, score=76.1]; MIR domain [PF02815.21, score=44.8]} {Human: ENSG00000123104, ITPR2, inositol 1,4,5-trisphosphate receptor type 2, [Score=214, Expect=5e-55]; ENSG00000150995, ITPR1, inositol 1,4,5-trisphosphate receptor type 1, [Score=205, Expect=3e-52]} {Mouse: ENSMUSG00000042644, Itpr3, inositol 1,4,5-triphosphate receptor 3, [Score=222, Expect=2e-57]; ENSMUSG00000030287, Itpr2, inositol 1,4,5-triphosphate receptor 2, [Score=213, Expect=8e-55]} {Dmel: FBgn0010051, Itp-r83A, Inositol 1,4,5,-tris-phosphate receptor, [Score=194, Expect=3e-49]} {Celegans: WBGene00002173, itr-1, Inositol 1,4,5-trisphosphate receptor itr-1, [Score=140, Expect=7e-33]} {Smed: dd_Smed_v6_3814_1_1, dd_Smed_v6_3814_1_1, [Score=1298, Expect=0.0]} {RNA1509_23724, RNA1509_55174, RNA1509_5518} {RNA1310_129.1, RNA1509_23724, RNA1509_55174, RNA1509_5518} {RNA1509_23724, RNA1509_55174, RNA1509_5518, RNA815_62.1}
19. MligTC455_16416 290 6.04 Mlig455_000468

Neo: -

Age: -

Region-enriched R2: 2.225/0.04782

ROR1 3.598 - - 0.754 0.924 0.942 0.978 Mlig455_000468 {REF} {Length: 2686} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=208.1]; Protein kinase domain [PF00069.27, score=77.3]; Kringle domain [PF00051.20, score=19.4]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [Score=300, Expect=1e-89]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [Score=295, Expect=2e-87]; ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [Score=281, Expect=2e-82]} {Dmel: FBgn0010407, Ror, [Score=259, Expect=2e-76]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=217, Expect=2e-60]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [Score=328, Expect=1e-100]} {RNA1509_35395} {RNA1310_13558} {RNA815_27446}
20. MligTC455_30617 647 13.47 Mlig455_031164

Neo: -

Age: logFC(26M/2M)=-0.513

ITPR1 3.587 - - 0.907 0.968 0.821 0.891 Mlig455_031164 {REF} {Length: 3978} {Pfam: RyR and IP3R Homology associated [PF08454.13, score=75.9]; Ion transport protein [PF00520.33, score=29.6]} {Human: ENSG00000150995, ITPR1, inositol 1,4,5-trisphosphate receptor type 1, [Score=157, Expect=3e-38]} {Mouse: ENSMUSG00000057378, Ryr3, ryanodine receptor 3, [Score=149, Expect=6e-36]; ENSMUSG00000030592, Ryr1, ryanodine receptor 1, skeletal muscle, [Score=148, Expect=1e-35]} {Dmel: FBgn0010051, Itp-r83A, Inositol 1,4,5,-tris-phosphate receptor, [Score=137, Expect=2e-32]} {Celegans: WBGene00002173, itr-1, Inositol 1,4,5-trisphosphate receptor itr-1, [Score=127, Expect=1e-29]} {Smed: dd_Smed_v6_3814_1_1, dd_Smed_v6_3814_1_1, [Score=598, Expect=0.0]} {RNA1509_42170} {RNA1310_129.1} {RNA815_62.1}
21. MligTC455_17778 198 4.12 Mlig455_021327

Neo: -

Age: -

3.581 - - 0.884 0.912 0.808 0.977 Mlig455_021327 {REF} {Length: 416} {TRANSSPLICED} {RNA1509_23323} {RNA1310_114939}
22. MligTC455_29408 45 0.94 Mlig455_038322

Neo: -

Age: -

Region-enriched R2: 8.586/0.00762

MB 3.58 - - 0.785 0.887 0.927 0.981 Mlig455_038322 {REF} {Length: 2059} {Pfam: Globin [PF00042.24, score=57.8]} {Human: ENSG00000198125, MB, myoglobin, [RH, Score=47.8, Expect=5e-07]} {Mouse: ENSMUSG00000018893, Mb, myoglobin, [RH, Score=45.4, Expect=2e-06]} {Celegans: WBGene00008996, glb-14, GLoBin related, [Score=51.6, Expect=4e-08]} {Smed: dd_Smed_v6_15997_0_1, dd_Smed_v6_15997_0_1, [RH, Score=63.5, Expect=1e-12]} {RNA1509_48898} {RNA1310_47695} {RNA815_7096.1}
23. MligTC455_16096 69 1.44 Mlig455_059809

Neo: -

Age: -

ANGPTL1 3.578 - - 0.872 0.952 0.769 0.985 Mlig455_059809 {REF} {Length: 1391} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=117.9]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=109, Expect=1e-26]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=106, Expect=2e-25]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=110, Expect=3e-27]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=105, Expect=2e-25]} {Dmel: FBgn0003326, sca, scabrous, [Score=91.3, Expect=3e-20]} {Celegans: WBGene00017013, ensh-1, [Score=61.2, Expect=1e-10]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=77.8, Expect=5e-16]} {RNA1509_28467} {RNA1310_47262} {RNA815_18070.1}
24. MligTC455_16148 198 4.12 Mlig455_057689

Neo: -

Age: -

KLHDC8A 3.57 - - 0.731 0.926 0.967 0.946 Mlig455_057689 {REF} {Length: 1806} {Pfam: Kelch motif [PF13964.8, score=56.9]; Kelch motif [PF01344.27, score=52.7]; Kelch motif [PF07646.17, score=37.5]; Galactose oxidase, central domain [PF13418.8, score=35.1]; Kelch motif [PF13854.8, score=27.6]} {Human: ENSG00000162873, KLHDC8A, kelch domain containing 8A, [Score=58.5, Expect=2e-09]} {Mouse: ENSMUSG00000042115, Klhdc8a, kelch domain containing 8A, [Score=63.9, Expect=1e-10]} {Smed: dd_Smed_v6_14507_0_1, dd_Smed_v6_14507_0_1, [RH, Score=209, Expect=4e-63]} {RNA1509_58319} {RNA1310_20213} {RNA815_8052}
25. MligTC455_50123 29 0.61 Mlig455_063710

Neo: -

Age: -

Region-enriched R4: 5.673/0.02044

3.556 - - 0.869 0.929 0.793 0.965 Mlig455_063710 {REF} {Length: 1119}
26. MligTC455_40289 93 1.94 Mlig455_017727, Mlig455_056175

Neo: -

Age: -

BMP1, CUBN 3.544 - - 0.788 0.866 0.980 0.910

Mlig455_017727 {REF} {Length: 1202} {Pfam: CUB domain [PF00431.22, score=55.3]} {Human: ENSG00000107611, CUBN, cubilin, [Score=54.7, Expect=4e-08]; ENSG00000168487, BMP1, bone morphogenetic protein 1, [Score=52.0, Expect=3e-07]} {Mouse: ENSMUSG00000026726, Cubn, cubilin (intrinsic factor-cobalamin receptor), [Score=51.6, Expect=3e-07]; ENSMUSG00000022098, Bmp1, bone morphogenetic protein 1, [Score=49.7, Expect=1e-06]} {Dmel: FBgn0003719, tld, tolloid, [Score=51.2, Expect=3e-07]} {Smed: dd_Smed_v6_69474_0_1, dd_Smed_v6_69474_0_1, [Score=47.4, Expect=2e-07]} {RNA1310_48745} {RNA815_23305}

Mlig455_056175 {REF} {Length: 2747} {Pfam: CUB domain [PF00431.22, score=62.6]} {Human: ENSG00000168487, BMP1, bone morphogenetic protein 1, [Score=52.8, Expect=2e-07]; ENSG00000107611, CUBN, cubilin, [Score=51.6, Expect=4e-07]} {Mouse: ENSMUSG00000022098, Bmp1, bone morphogenetic protein 1, [Score=51.6, Expect=3e-07]; ENSMUSG00000026726, Cubn, cubilin (intrinsic factor-cobalamin receptor), [Score=49.7, Expect=1e-06]} {Dmel: FBgn0003719, tld, tolloid, [Score=51.2, Expect=3e-07]} {Smed: dd_Smed_v6_69474_0_1, dd_Smed_v6_69474_0_1, [Score=47.0, Expect=3e-07]} {RNA1310_48745} {RNA815_23305}
27. MligTC455_35895 102 2.12 Mlig455_063971

Neo: -

Age: -

RYK 3.533 - - 0.823 0.835 0.910 0.965 Mlig455_063971 {REF} {Length: 3496} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=209.4]; WIF domain [PF02019.20, score=109.7]; Protein kinase domain [PF00069.27, score=79.1]} {Human: ENSG00000163785, RYK, receptor-like tyrosine kinase, [Score=202, Expect=1e-55]} {Mouse: ENSMUSG00000032547, Ryk, receptor-like tyrosine kinase, [RH, Score=202, Expect=2e-55]} {Dmel: FBgn0015380, drl, derailed, [RH, Score=239, Expect=4e-69]} {Celegans: WBGene00003007, lin-18, Inactive tyrosine-protein kinase RYK, [Score=179, Expect=6e-48]} {Smed: dd_Smed_v6_12594_0_2, dd_Smed_v6_12594_0_2, [Score=201, Expect=3e-55]} {RNA1509_58811} {RNA1310_6671.2} {RNA815_41921}
28. MligTC455_45051 307 6.41 Mlig455_043687, Mlig455_043755

Neo: -

Age: -

3.533 - - 0.786 0.899 0.965 0.883

Mlig455_043687 {REF} {Length: 1460} {RNA1310_17293.1}

Mlig455_043755 {REF} {Length: 1366} {TRANSSPLICED} {RNA1310_17293.1}
29. MligTC455_25464 185 3.85 Mlig455_001339

Neo: -

Age: -

Region-enriched R2: 4.725/0.00025

3.525 - - 0.866 0.923 0.777 0.959 Mlig455_001339 {REF} {Length: 1386} {RNA1509_58508} {RNA1310_32754, RNA1509_58508} {RNA1509_58508, RNA815_47065}
30. MligTC455_17464 409 8.52 Mlig455_048989, Mlig455_049006, Mlig455_067762

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.512

Regeneration-downregulated BL: -7.800

Regeneration-depleted BL: -7.800

3.524 - - 0.737 0.940 0.864 0.983

Mlig455_048989 {REF} {Length: 1272} {RNA1310_37715} {RNA815_39767}

Mlig455_049006 {REF} {Length: 1028} {RNA1310_37715} {RNA815_39767}

Mlig455_067762 {REF} {Length: 1353} {RNA1310_37715} {RNA815_39767}
31. MligTC455_16874 38 0.8 Mlig455_028170

Neo: -

Age: -

KCNK18 3.523 - - 0.889 0.951 0.701 0.982 Mlig455_028170 {REF} {Length: 2452} {Pfam: Ion channel [PF07885.18, score=103.1]; Protein of unknown function (DUF3112) [PF11309.10, score=20.2]} {Human: ENSG00000186795, KCNK18, potassium two pore domain channel subfamily K member 18, [Score=96.7, Expect=1e-21]} {Mouse: ENSMUSG00000040901, Kcnk18, potassium channel, subfamily K, member 18, [Score=101, Expect=2e-23]} {Dmel: FBgn0033257, sand, sandman, [Score=129, Expect=2e-33]} {Celegans: WBGene00006680, twk-28, TWiK family of potassium channels, [Score=144, Expect=3e-38]} {Smed: dd_Smed_v6_17586_0_1, dd_Smed_v6_17586_0_1, [Score=270, Expect=2e-87]} {RNA1509_39975} {RNA1310_18301.1} {RNA815_12440}
32. MligTC455_13885 28 0.58 Mlig455_020919

Neo: -

Age: -

3.513 - - 0.865 0.919 0.749 0.980 Mlig455_020919 {REF} {Length: 1208} {RNA1310_25040.4} {RNA815_12562.1}
33. MligTC455_51559 43 0.89 Mlig455_002923, Mlig455_002941

Neo: -

Age: -

Region-enriched R2: 6.806/0.01463

3.509 - - 0.805 0.930 0.793 0.981

Mlig455_002923 {REF} {Length: 1008} {RNA1310_77227} {RNA815_43894}

Mlig455_002941 {REF} {Length: 897} {RNA1310_88681} {RNA815_43894}
34. MligTC455_41055 112 2.34 Mlig455_044574

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.659

Region-enriched R2: 6.247/0.00008

3.508 - - 0.957 0.841 0.729 0.981 Mlig455_044574 {REF} {Length: 1203} {Smed: dd_Smed_v6_9736_0_1, dd_Smed_v6_9736_0_1, [Score=86.7, Expect=1e-20]} {RNA1509_58567} {RNA1310_87689} {RNA815_53353}
35. MligTC455_49448 237 4.94 Mlig455_057665

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.549

PRKCQ 3.494 - - 0.957 0.860 0.740 0.937 Mlig455_057665 {REF} {Length: 2763} {Pfam: Protein kinase domain [PF00069.27, score=119.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=84.8]; Kinase-like [PF14531.8, score=23.9]} {Human: ENSG00000065675, PRKCQ, protein kinase C theta, [Score=90.1, Expect=1e-18]; ENSG00000067606, PRKCZ, protein kinase C zeta, [Score=89.4, Expect=2e-18]; ENSG00000281877, RPS6KA1, ribosomal protein S6 kinase A1, [Score=88.6, Expect=4e-18]; ENSG00000117676, RPS6KA1, ribosomal protein S6 kinase A1, [Score=88.6, Expect=4e-18]; ENSG00000163558, PRKCI, protein kinase C iota, [Score=88.2, Expect=5e-18]; ENSG00000108443, RPS6KB1, ribosomal protein S6 kinase B1, [Score=87.8, Expect=5e-18]; ENSG00000027075, PRKCH, protein kinase C eta, [Score=85.9, Expect=2e-17]; ENSG00000171132, PRKCE, protein kinase C epsilon, [Score=85.9, Expect=4e-17]} {Mouse: ENSMUSG00000029053, Prkcz, protein kinase C, zeta, [Score=88.6, Expect=3e-18]; ENSMUSG00000003644, Rps6ka1, ribosomal protein S6 kinase polypeptide 1, [Score=88.2, Expect=4e-18]; ENSMUSG00000021108, Prkch, protein kinase C, eta, [Score=87.8, Expect=5e-18]; ENSMUSG00000037643, Prkci, protein kinase C, iota, [Score=87.8, Expect=4e-18]; ENSMUSG00000020516, Rps6kb1, ribosomal protein S6 kinase, polypeptide 1, [Score=87.8, Expect=4e-18]; ENSMUSG00000031309, Rps6ka3, ribosomal protein S6 kinase polypeptide 3, [Score=87.4, Expect=7e-18]; ENSMUSG00000116203, Rps6ka6, ribosomal protein S6 kinase polypeptide 6, [Score=84.7, Expect=6e-17]; ENSMUSG00000045038, Prkce, protein kinase C, epsilon, [Score=84.7, Expect=6e-17]; ENSMUSG00000025665, Rps6ka6, ribosomal protein S6 kinase polypeptide 6, [Score=84.7, Expect=6e-17]; ENSMUSG00000026778, Prkcq, protein kinase C, theta, [Score=84.3, Expect=7e-17]; ENSMUSG00000019699, Akt3, thymoma viral proto-oncogene 3, [Score=84.3, Expect=4e-17]} {Dmel: FBgn0003093, Pkc98E, Protein C kinase 98E, [Score=86.7, Expect=7e-18]} {Celegans: WBGene00004032, pkc-1, Protein kinase C-like 1B, [Score=84.7, Expect=3e-17]} {Smed: dd_Smed_v6_8010_0_1, dd_Smed_v6_8010_0_1, [Score=88.2, Expect=2e-18]} {RNA1509_57646} {RNA1310_18713, RNA1509_57646} {RNA1509_57646, RNA815_7871}
36. MligTC455_46605 388 8.08 Mlig455_032055

Neo: -

Age: -

Region-specific R2: 4.152

3.493 - - 0.847 0.770 0.914 0.962 Mlig455_032055 {REF} {Length: 1416} {RNA1310_44339} {RNA815_20624}
37. MligTC455_48522 94 1.96 Mlig455_032491

Neo: -

Age: -

Region-enriched R2: 4.888/0.01251

3.493 - - 0.887 0.721 0.962 0.923 Mlig455_032491 {REF} {Length: 2169} {Pfam: Sodium / potassium ATPase beta chain [PF00287.20, score=47.3]} {Dmel: FBgn0015776, nrv1, nervana 1, [Score=55.5, Expect=2e-08]} {RNA1310_12303} {RNA815_10417}
38. MligTC455_48987 452 9.42 Mlig455_045280

Neo: -

Age: logFC(26M/2M)=-0.491

TRPM2 3.493 - - 0.711 0.916 0.955 0.911 Mlig455_045280 {REF} {Length: 4575} {Pfam: SLOG in TRPM [PF18139.3, score=216.5]; SLOG in TRPM, prokaryote [PF18171.3, score=65.0]; Ion transport protein [PF00520.33, score=58.8]} {Human: ENSG00000142185, TRPM2, transient receptor potential cation channel subfamily M member 2, [Score=420, Expect=3e-123]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [RH, Score=500, Expect=1e-150]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=293, Expect=2e-81]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=248, Expect=2e-66]} {Smed: dd_Smed_v6_13119_0_1, dd_Smed_v6_13119_0_1, [RH, Score=630, Expect=0.0]} {RNA1509_8528} {RNA1310_1728.1, RNA1509_8528} {RNA1509_8528, RNA815_888}
39. MligTC455_14873 15 0.31 Mlig455_021074

Neo: -

Age: -

3.492 - - 0.863 0.861 0.793 0.975 Mlig455_021074 {REF} {Length: 1075} {Pfam: WSC domain [PF01822.21, score=52.6]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=46.6, Expect=8e-06]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=50.8, Expect=2e-07]} {RNA1310_33352.1} {RNA815_14158.1}
40. MligTC455_49578 920 19.17 Mlig455_042519

Neo: -

Age: logFC(26M/2M)=-0.236

Region-enriched R2: 1.433/0.00873

ANO7 3.488 - - 0.835 0.897 0.952 0.804 Mlig455_042519 {REF} {Length: 3579} {Pfam: Calcium-activated chloride channel [PF04547.14, score=222.4]; Dimerisation domain of Ca+-activated chloride-channel, anoctamin [PF16178.7, score=30.6]} {Human: ENSG00000146205, ANO7, anoctamin 7, [Score=114, Expect=3e-25]} {Mouse: ENSMUSG00000034107, Ano7, anoctamin 7, [Score=120, Expect=3e-27]} {Dmel: FBgn0038721, subdued, [Score=117, Expect=2e-26]} {Celegans: WBGene00010138, anoh-1, Anoctamin, [Score=161, Expect=1e-40]} {Smed: dd_Smed_v6_6514_0_4, dd_Smed_v6_6514_0_4, [Score=126, Expect=2e-29]} {RNA1509_19842, RNA1509_21022, RNA1509_21269} {RNA1310_4099.1, RNA1509_19842, RNA1509_21022} {RNA1509_19842, RNA1509_21022, RNA815_1067}
41. MligTC455_50915 531 11.06 Mlig455_028745

Neo: -

Age: Up-Down-Down

Region-enriched R2: 2.109/0.02468

DNHD1 3.487 - - 0.845 0.903 0.954 0.785 Mlig455_028745 {REF} {Length: 14999} {TRANSSPLICED} {Pfam: Dynein heavy chain, N-terminal region 2 [PF08393.15, score=214.3]; Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=113.4]; P-loop containing dynein motor region D4 [PF12780.9, score=60.1]; Microtubule-binding stalk of dynein motor [PF12777.9, score=55.6]; P-loop containing dynein motor region [PF12775.9, score=49.4]; Dynein heavy chain C-terminal domain [PF18199.3, score=44.7]; Dynein heavy chain AAA lid domain [PF17852.3, score=40.5]; AAA domain [PF13401.8, score=23.5]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=22.3]; Dynein heavy chain AAA lid domain [PF18198.3, score=22.0]; Protein of unknown function (DUF815) [PF05673.15, score=21.1]; AAA domain [PF13604.8, score=18.7]} {Human: ENSG00000179532, DNHD1, dynein heavy chain domain 1, [Score=157, Expect=4e-37]} {Mouse: ENSMUSG00000030882, Dnhd1, dynein heavy chain domain 1, [Score=249, Expect=8e-65]} {Dmel: FBgn0013811, Dhc62B, Dynein heavy chain at 62B, [Score=114, Expect=2e-24]} {Celegans: WBGene00000485, che-3, Cytoplasmic dynein 2 heavy chain 1, [Score=84.0, Expect=4e-15]} {Smed: dd_Smed_v6_8984_0_1, dd_Smed_v6_8984_0_1, [RH, Score=443, Expect=5e-124]} {RNA1509_1896} {RNA1310_31, RNA1509_1896} {RNA1509_1896, RNA815_1203}
42. MligTC455_49307 122 2.55 Mlig455_055230

Neo: -

Age: -

Region-enriched R2: 4.447/0.04819

ZAN 3.469 - - 0.748 0.832 0.967 0.922 Mlig455_055230 {REF} {Length: 2947} {Pfam: Glycine rich protein [PF12810.9, score=28.6]} {Human: ENSG00000146839, ZAN, zonadhesin (gene/pseudogene), [Score=79.7, Expect=1e-14]} {Mouse: ENSMUSG00000079173, Zan, zonadhesin, [Score=80.1, Expect=7e-15]} {RNA1310_18897} {RNA815_40026}
43. MligTC455_39467 6156 128.24 Mlig455_066728, Mlig455_066742

Neo: -

Age: logFC(26M/2M)=-0.137

Region-specific R2: 2.002

Region-enriched R2: 1.402/0.00004

PC 3.467 - - 0.889 0.796 0.952 0.830

Mlig455_066728 {REF} {Length: 4310} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=220.4]; Conserved carboxylase domain [PF02436.20, score=216.0]; Biotin carboxylase, N-terminal domain [PF00289.24, score=144.7]; Biotin carboxylase C-terminal domain [PF02785.21, score=102.8]; HMGL-like [PF00682.21, score=93.0]; Biotin-requiring enzyme [PF00364.24, score=57.9]; Biotin-lipoyl like [PF13533.8, score=28.3]; D-ala D-ala ligase C-terminus [PF07478.15, score=25.5]; ATP-grasp domain [PF02222.24, score=24.6]} {Human: ENSG00000173599, PC, pyruvate carboxylase, [Score=1375, Expect=0.0]} {Mouse: ENSMUSG00000024892, Pcx, pyruvate carboxylase, [Score=1365, Expect=0.0]} {Dmel: FBgn0027580, PCB, Pyruvate carboxylase, [Score=1419, Expect=0.0]} {Celegans: WBGene00004258, pyc-1, Pyruvate carboxylase 1, [Score=1371, Expect=0.0]} {Smed: dd_Smed_v6_2393_0_1, dd_Smed_v6_2393_0_1, [Score=1440, Expect=0.0]} {RNA1509_292} {RNA1310_1178} {RNA815_516.1}

Mlig455_066742 {REF} {Length: 4334} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=265.4]; Biotin carboxylase, N-terminal domain [PF00289.24, score=117.2]; Biotin carboxylase C-terminal domain [PF02785.21, score=104.0]; ATP-grasp domain [PF02222.24, score=37.0]; D-ala D-ala ligase C-terminus [PF07478.15, score=34.3]; ATP-grasp domain [PF02655.16, score=18.8]; HMGL-like [PF00682.21, score=18.3]} {Human: ENSG00000173599, PC, pyruvate carboxylase, [Score=837, Expect=0.0]} {Mouse: ENSMUSG00000024892, Pcx, pyruvate carboxylase, [Score=826, Expect=0.0]} {Dmel: FBgn0027580, PCB, Pyruvate carboxylase, [Score=839, Expect=0.0]} {Celegans: WBGene00004258, pyc-1, Pyruvate carboxylase 1, [Score=808, Expect=0.0]} {Smed: dd_Smed_v6_2393_0_1, dd_Smed_v6_2393_0_1, [Score=851, Expect=0.0]} {RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579} {RNA1310_1642, RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579} {RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579, RNA815_516.1}
44. MligTC455_36729 109 2.26 Mlig455_031568

Neo: -

Age: -

Region-enriched R2: 4.085/0.04774

3.465 - - 0.951 0.909 0.704 0.901 Mlig455_031568 {REF} {Length: 4709} {RNA1310_20703.1} {RNA815_12377}
45. MligTC455_39096 110 2.29 Mlig455_019781, Mlig455_019803

Neo: -

Age: -

3.457 - - 0.830 0.906 0.741 0.980

Mlig455_019781 {REF} {Length: 1107} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=65.0]} {RNA1310_34740} {RNA815_15663}

Mlig455_019803 {REF} {Length: 1107} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=63.1]} {RNA1310_34740} {RNA815_15663}
46. MligTC455_20149 191 3.98 Mlig455_000246, Mlig455_058518

Neo: -

Age: -

Region-enriched R2: 4.445/0.03524

HPCAL4, NCALD 3.45 - - 0.845 0.777 0.856 0.972

Mlig455_000246 {REF} {Length: 978} {Human: ENSG00000116983, HPCAL4, hippocalcin like 4, [Score=79.0, Expect=2e-17]; ENSG00000104490, NCALD, neurocalcin delta, [Score=79.0, Expect=2e-17]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=77.8, Expect=5e-17]; ENSG00000185774, KCNIP4, potassium voltage-gated channel interacting protein 4, [Score=75.5, Expect=1e-15]} {Mouse: ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=79.0, Expect=1e-17]; ENSMUSG00000046093, Hpcal4, hippocalcin-like 4, [Score=79.0, Expect=1e-17]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=77.0, Expect=7e-17]; ENSMUSG00000029088, Kcnip4, Kv channel interacting protein 4, [Score=75.5, Expect=8e-16]} {Dmel: FBgn0013303, Nca, Neurocalcin, [Score=83.2, Expect=3e-19]} {Celegans: WBGene00003563, ncs-1, Neuronal calcium sensor 1, [Score=67.8, Expect=1e-13]} {Smed: dd_Smed_v6_2568_0_1, dd_Smed_v6_2568_0_1, [Score=72.0, Expect=2e-15]} {RNA1310_101382}

Mlig455_058518 {REF} {Length: 1176} {Human: ENSG00000104490, NCALD, neurocalcin delta, [Score=82.0, Expect=2e-18]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=81.3, Expect=3e-18]; ENSG00000116983, HPCAL4, hippocalcin like 4, [Score=80.1, Expect=7e-18]} {Mouse: ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=82.0, Expect=8e-19]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=80.5, Expect=4e-18]; ENSMUSG00000046093, Hpcal4, hippocalcin-like 4, [Score=80.1, Expect=5e-18]} {Dmel: FBgn0013303, Nca, Neurocalcin, [Score=84.0, Expect=1e-19]} {Celegans: WBGene00003563, ncs-1, Neuronal calcium sensor 1, [Score=67.0, Expect=2e-13]} {Smed: dd_Smed_v6_2568_0_1, dd_Smed_v6_2568_0_1, [Score=73.2, Expect=8e-16]} {RNA1310_101382}
47. MligTC455_50344 24 0.51 Mlig455_054355

Neo: -

Age: -

3.441 - - 0.872 0.883 0.705 0.981 Mlig455_054355 {REF} {Length: 1376} {RNA1310_56750}
48. MligTC455_39179 44 0.91 Mlig455_052012

Neo: -

Age: Down-Up-Up

TCTE3 3.434 - - 0.814 0.932 0.706 0.982 Mlig455_052012 {REF} {Length: 1042} {Pfam: Tctex-1 family [PF03645.15, score=42.5]} {Human: ENSG00000184786, TCTE3, t-complex-associated-testis-expressed 3, [RH, Score=65.9, Expect=8e-13]; ENSG00000275368, TCTE3, t-complex-associated-testis-expressed 3, [RH, Score=65.9, Expect=8e-13]} {Mouse: ENSMUSG00000028523, Tctex1d1, Tctex1 domain containing 1, [Score=61.6, Expect=1e-11]} {Smed: dd_Smed_v6_9036_0_1, dd_Smed_v6_9036_0_1, [Score=92.8, Expect=1e-23]} {RNA1509_34873} {RNA1310_34743} {RNA815_18661}
49. MligTC455_39845 141 2.94 Mlig455_002533, Mlig455_002635

Neo: -

Age: -

Region-enriched R2: 3.456/0.04589

DLX6 3.418 - - 0.783 0.886 0.789 0.960

Mlig455_002533 {REF} {Length: 2344} {Pfam: Homeodomain [PF00046.31, score=75.8]} {Human: ENSG00000006377, DLX6, distal-less homeobox 6, [RH, Score=135, Expect=3e-36]} {Mouse: ENSMUSG00000029754, Dlx6, distal-less homeobox 6, [RH, Score=136, Expect=1e-36]} {Dmel: FBgn0000157, Dll, Distal-less, [RH, Score=135, Expect=4e-36]} {Celegans: WBGene00000463, ceh-43, Homeobox protein ceh-43, [RH, Score=107, Expect=2e-26]} {Smed: dd_Smed_v6_19040_0_1, dd_Smed_v6_19040_0_1, [RH, Score=151, Expect=9e-41]} {RNA1509_39701} {RNA1310_10459.1, RNA1509_39701} {RNA1509_39701, RNA815_21765}

Mlig455_002635 {REF} {Length: 2355} {Pfam: Homeodomain [PF00046.31, score=74.4]} {Human: ENSG00000006377, DLX6, distal-less homeobox 6, [RH, Score=135, Expect=3e-36]} {Mouse: ENSMUSG00000029754, Dlx6, distal-less homeobox 6, [RH, Score=136, Expect=1e-36]} {Dmel: FBgn0000157, Dll, Distal-less, [RH, Score=135, Expect=4e-36]} {Celegans: WBGene00000463, ceh-43, Homeobox protein ceh-43, [RH, Score=107, Expect=2e-26]} {Smed: dd_Smed_v6_19040_0_1, dd_Smed_v6_19040_0_1, [RH, Score=151, Expect=1e-40]} {RNA1509_39701} {RNA1310_10459.1} {RNA815_21765}
50. MligTC455_25971 151 3.14 Mlig455_009163

Neo: -

Age: -

Regeneration-downregulated BL: -6.673

Regeneration-depleted BL: -6.673

3.415 - - 0.792 0.893 0.775 0.955 Mlig455_009163 {REF} {Length: 2858} {RNA1509_41399} {RNA1310_25715, RNA1509_41399} {RNA1509_41399, RNA815_12763}
51. MligTC455_47160 747 15.56 Mlig455_021750

Neo: -

Age: logFC(26M/2M)=-0.246

FAM184A 3.413 - - 0.800 0.834 0.967 0.812 Mlig455_021750 {REF} {Length: 3705} {Pfam: Family with sequence similarity 184, A and B [PF15665.7, score=130.1]} {Human: ENSG00000111879, FAM184A, family with sequence similarity 184 member A, [RH, Score=340, Expect=5e-99]} {Mouse: ENSMUSG00000019856, Fam184a, family with sequence similarity 184, member A, [RH, Score=308, Expect=7e-88]} {Celegans: WBGene00001328, epi-1, Laminin-like protein epi-1, [Score=60.8, Expect=5e-09]} {Smed: dd_Smed_v6_16975_0_1, dd_Smed_v6_16975_0_1, [RH, Score=264, Expect=3e-73]} {RNA1509_5806} {RNA1310_3258.1, RNA1509_5806} {RNA1509_5806, RNA815_936}
52. MligTC455_48766 985 20.53 Mlig455_020052, Mlig455_022298

Neo: -

Age: logFC(26M/2M)=-0.287

ODF3 3.413 - - 0.730 0.918 0.801 0.964

Mlig455_020052 {REF} {Length: 1742} {TRANSSPLICED} {Pfam: Sperm-tail PG-rich repeat [PF07004.14, score=82.0]} {Human: ENSG00000177947, ODF3, outer dense fiber of sperm tails 3, [RH, Score=188, Expect=6e-59]} {Mouse: ENSMUSG00000025482, Odf3, outer dense fiber of sperm tails 3, [RH, Score=187, Expect=1e-58]} {Dmel: FBgn0032010, CG8086, [RH, Score=119, Expect=2e-32]} {Smed: dd_Smed_v6_2658_0_1, dd_Smed_v6_2658_0_1, [Score=304, Expect=4e-105]} {RNA1509_28289, RNA1509_56680} {RNA1310_15149, RNA1509_56680} {RNA1509_56680, RNA815_9422}

Mlig455_022298 {REF} {Length: 2031} {TRANSSPLICED} {Pfam: Sperm-tail PG-rich repeat [PF07004.14, score=82.0]} {Human: ENSG00000177947, ODF3, outer dense fiber of sperm tails 3, [RH, Score=188, Expect=6e-59]} {Mouse: ENSMUSG00000025482, Odf3, outer dense fiber of sperm tails 3, [RH, Score=187, Expect=1e-58]} {Dmel: FBgn0032010, CG8086, [RH, Score=119, Expect=2e-32]} {Smed: dd_Smed_v6_2658_0_1, dd_Smed_v6_2658_0_1, [Score=304, Expect=4e-105]} {RNA1509_28289, RNA1509_54276} {RNA1310_15149, RNA1509_28289, RNA1509_54276} {RNA1509_28289, RNA1509_54276, RNA815_9422}
53. MligTC455_25311 348 7.26 Mlig455_011485, Mlig455_011570

Neo: -

Age: -

RPGR 3.408 - - 0.750 0.904 0.777 0.977

Mlig455_011485 {REF} {Length: 3239} {Pfam: Regulator of chromosome condensation (RCC1) repeat [PF00415.20, score=191.7]; Regulator of chromosome condensation (RCC1) repeat [PF13540.8, score=144.3]; PapC C-terminal domain [PF13953.8, score=19.2]} {Human: ENSG00000156313, RPGR, retinitis pigmentosa GTPase regulator, [RH, Score=232, Expect=2e-64]} {Mouse: ENSMUSG00000031174, Rpgr, retinitis pigmentosa GTPase regulator, [RH, Score=238, Expect=8e-67]} {Dmel: FBgn0035207, Sherpa, SUMO-related HECT domain and RCC repeat protein for Toll pathway activation, [Score=136, Expect=9e-33]} {Celegans: WBGene00021685, herc-1, HECT and RCC domain E3 ubiquitin ligase, [Score=120, Expect=8e-28]} {Smed: dd_Smed_v6_2716_1_1, dd_Smed_v6_2716_1_1, [RH, Score=221, Expect=3e-63]} {RNA1509_19349} {RNA1310_8792, RNA1509_19349} {RNA1509_19349, RNA815_24692}

Mlig455_011570 {REF} {Length: 3224} {Pfam: Regulator of chromosome condensation (RCC1) repeat [PF00415.20, score=193.1]; Regulator of chromosome condensation (RCC1) repeat [PF13540.8, score=144.3]; PapC C-terminal domain [PF13953.8, score=19.2]} {Human: ENSG00000156313, RPGR, retinitis pigmentosa GTPase regulator, [RH, Score=233, Expect=2e-64]} {Mouse: ENSMUSG00000031174, Rpgr, retinitis pigmentosa GTPase regulator, [RH, Score=239, Expect=6e-67]} {Dmel: FBgn0035207, Sherpa, SUMO-related HECT domain and RCC repeat protein for Toll pathway activation, [Score=136, Expect=9e-33]} {Celegans: WBGene00021685, herc-1, HECT and RCC domain E3 ubiquitin ligase, [Score=121, Expect=4e-28]} {Smed: dd_Smed_v6_2716_1_1, dd_Smed_v6_2716_1_1, [RH, Score=222, Expect=1e-63]} {RNA1509_19349} {RNA1310_8792} {RNA815_24692}
54. MligTC455_43581 177 3.68 Mlig455_042725, Mlig455_042827, Mlig455_063146

Neo: -

Age: Up-Down-Down

GRIA2 3.394 - - 0.792 0.955 0.702 0.945

Mlig455_042725 {REF} {Length: 3074} {Pfam: Ligand-gated ion channel [PF00060.28, score=104.7]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=44.7]; Receptor family ligand binding region [PF01094.30, score=33.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=19.7]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=153, Expect=1e-37]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=149, Expect=2e-36]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=147, Expect=7e-36]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=152, Expect=2e-37]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=148, Expect=3e-36]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=147, Expect=8e-36]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=145, Expect=2e-35]} {Dmel: FBgn0038837, CG3822, [Score=140, Expect=5e-34]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=126, Expect=1e-29]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=253, Expect=2e-76]} {RNA1310_25150} {RNA815_13942}

Mlig455_042827 {REF} {Length: 2869} {Pfam: Ligand-gated ion channel [PF00060.28, score=83.9]; Receptor family ligand binding region [PF01094.30, score=49.8]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=44.8]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=20.3]; Iron-containing alcohol dehydrogenase [PF13685.8, score=18.6]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=125, Expect=6e-29]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=122, Expect=5e-28]; ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=121, Expect=7e-28]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=120, Expect=2e-27]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=125, Expect=5e-29]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=122, Expect=4e-28]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=121, Expect=1e-27]; ENSMUSG00000041078, Grid1, glutamate receptor, ionotropic, delta 1, [Score=120, Expect=1e-27]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=119, Expect=3e-27]} {Dmel: FBgn0039927, CG11155, [Score=127, Expect=7e-30]} {Celegans: WBGene00001612, glr-1, Glutamate receptor 1, [Score=103, Expect=1e-22]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=217, Expect=2e-63]} {RNA1310_25150} {RNA815_13942}

Mlig455_063146 {REF} {Length: 2444} {Pfam: Receptor family ligand binding region [PF01094.30, score=35.8]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=82.4, Expect=1e-16]} {RNA1310_25150} {RNA815_13999}
55. MligTC455_47875 72 1.5 Mlig455_067941

Neo: -

Age: -

3.39 - - 0.881 0.960 0.832 0.717 Mlig455_067941 {REF} {Length: 1399} {Smed: dd_Smed_v6_3944_0_1, dd_Smed_v6_3944_0_1, [Score=97.8, Expect=7e-26]} {RNA1509_55952} {RNA1310_12426} {RNA815_33214}
56. MligTC455_40610 165 3.43 Mlig455_064484

Neo: -

Age: -

Region-enriched R2: 5.617/0.00105

3.357 - - 0.728 0.936 0.712 0.981 Mlig455_064484 {REF} {Length: 2931} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=24.9]} {Smed: dd_Smed_v6_41498_0_1, dd_Smed_v6_41498_0_1, [Score=154, Expect=2e-40]} {RNA1509_26568} {RNA1310_9342.1, RNA1509_26568} {RNA1509_26568, RNA815_7018}
57. MligTC455_45039 168 3.49 Mlig455_040482, Mlig455_040487

Neo: -

Age: Down-Up-Down

Region-enriched R2: 5.332/0.02336

3.357 - - 0.794 0.791 0.789 0.983

Mlig455_040482 {REF} {Length: 1774} {RNA1310_20941} {RNA815_45079}

Mlig455_040487 {REF} {Length: 5763} {tRNA: Val(CAC),pseudo, score=20.2} {Celegans: WBGene00022195, Y71H2B.5, [Score=146, Expect=8e-36]} {Smed: dd_Smed_v6_16438_0_2, dd_Smed_v6_16438_0_2, [Score=188, Expect=1e-49]} {RNA1509_21228} {RNA1310_20941} {RNA815_45079}
58. MligTC455_49285 164 3.41 Mlig455_004486, Mlig455_037380

Neo: -

Age: -

Region-specific R2: 6.095

Region-enriched R2: 5.942/0.00244

LEF1 3.355 0.728 - 0.921 - 0.742 0.964

Mlig455_004486 {REF} {Length: 3612} {Pfam: HMG (high mobility group) box [PF00505.21, score=30.1]} {Human: ENSG00000138795, LEF1, lymphoid enhancer binding factor 1, [Score=105, Expect=2e-24]; ENSG00000081059, TCF7, transcription factor 7, [Score=103, Expect=3e-25]; ENSG00000152284, TCF7L1, transcription factor 7 like 1, [Score=100, Expect=2e-22]} {Mouse: ENSMUSG00000027985, Lef1, lymphoid enhancer binding factor 1, [Score=105, Expect=6e-25]; ENSMUSG00000000782, Tcf7, transcription factor 7, T cell specific, [Score=101, Expect=8e-24]; ENSMUSG00000055799, Tcf7l1, transcription factor 7 like 1 (T cell specific, HMG box), [Score=100, Expect=1e-22]} {Dmel: FBgn0085432, pan, pangolin, [Score=103, Expect=1e-23]} {Celegans: WBGene00004077, pop-1, [Score=82.0, Expect=8e-17]} {Smed: dd_Smed_v6_34144_0_1, dd_Smed_v6_34144_0_1, [Score=114, Expect=3e-29]} {RNA1509_13914} {RNA1310_16097} {RNA815_47141}

Mlig455_037380 {REF} {Length: 3365} {Pfam: HMG (high mobility group) box [PF00505.21, score=78.7]; HMG-box domain [PF09011.12, score=32.5]} {Human: ENSG00000138795, LEF1, lymphoid enhancer binding factor 1, [RH, Score=156, Expect=1e-43]; ENSG00000152284, TCF7L1, transcription factor 7 like 1, [RH, Score=154, Expect=7e-41]; ENSG00000081059, TCF7, transcription factor 7, [RH, Score=154, Expect=3e-44]; ENSG00000148737, TCF7L2, transcription factor 7 like 2, [RH, Score=150, Expect=6e-44]} {Mouse: ENSMUSG00000027985, Lef1, lymphoid enhancer binding factor 1, [RH, Score=157, Expect=9e-44]; ENSMUSG00000055799, Tcf7l1, transcription factor 7 like 1 (T cell specific, HMG box), [RH, Score=156, Expect=1e-41]; ENSMUSG00000000782, Tcf7, transcription factor 7, T cell specific, [RH, Score=153, Expect=1e-42]} {Dmel: FBgn0085432, pan, pangolin, [RH, Score=155, Expect=1e-40]} {Celegans: WBGene00004077, pop-1, [Score=104, Expect=4e-24]} {Smed: dd_Smed_v6_34144_0_1, dd_Smed_v6_34144_0_1, [RH, Score=165, Expect=2e-48]} {RNA1509_13914} {RNA1310_16097} {RNA815_47141}
59. MligTC455_15679 88 1.82 Mlig455_057219

Neo: -

Age: Down-Up-Up

WSCD2 3.34 - - 0.780 0.862 0.717 0.981 Mlig455_057219 {REF} {Length: 1035} {Pfam: WSC domain [PF01822.21, score=55.1]; PAN domain [PF00024.28, score=27.0]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=52.8, Expect=2e-07]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=51.6, Expect=3e-07]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=53.5, Expect=5e-08]} {RNA1509_46267} {RNA1310_46146} {RNA815_32275.1}
60. MligTC455_37685 4152 86.5 Mlig455_023075

Neo: -

Age: logFC(26M/2M)=-0.351

DNALI1 3.292 - - 0.783 0.951 0.768 0.790 Mlig455_023075 {REF} {Length: 888} {Pfam: Axonemal dynein light chain [PF10211.11, score=216.0]; Apg6 coiled-coil region [PF17675.3, score=21.3]; Homeobox associated leucine zipper [PF02183.20, score=20.2]; RIB43A [PF05914.14, score=19.8]; Autophagy protein ATG17-like domain [PF04108.14, score=18.5]} {Human: ENSG00000163879, DNALI1, dynein axonemal light intermediate chain 1, [Score=237, Expect=9e-79]} {Mouse: ENSMUSG00000042707, Dnali1, dynein, axonemal, light intermediate polypeptide 1, [Score=235, Expect=2e-78]} {Dmel: FBgn0037962, CG6971, [Score=179, Expect=1e-56]} {Celegans: WBGene00018307, dyla-1, DYnein Light chain, Axonemal p28 type, [Score=123, Expect=7e-35]} {Smed: dd_Smed_v6_4453_0_1, dd_Smed_v6_4453_0_1, [Score=251, Expect=3e-85]} {RNA1509_10001} {RNA1310_27688.2} {RNA815_9783}
61. MligTC455_19277 1013 21.11 Mlig455_059600

Neo: -

Age: -

Region-specific R2: 4.883

Region-enriched R2: 5.766/0.00000
Region-enriched R3: 2.030/0.00976

3.24 - - 0.741 0.714 0.824 0.961 Mlig455_059600 {REF} {Length: 827} {NoTransDecoderORF} {RNA1509_43907} {RNA1310_81348}
62. MligTC455_50567 146 3.04 Mlig455_012858

Neo: -

Age: -

Region-specific R2: 6.162

Region-enriched R2: 5.988/0.01054

3.153 - - 0.752 0.732 0.951 0.718 Mlig455_012858 {REF} {Length: 1282} {Pfam: F5/8 type C domain [PF00754.27, score=27.5]} {Smed: dd_Smed_v6_36585_0_1, dd_Smed_v6_36585_0_1, [RH, Score=64.3, Expect=4e-12]} {RNA1310_34633} {RNA815_12537}
63. MligTC455_22150 189 3.94 Mlig455_054947

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=2.071

XDH 2.881 - - 0.938 0.979 - 0.964 Mlig455_054947 {REF} {Length: 5481} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=346.4]; [2Fe-2S] binding domain [PF01799.22, score=95.7]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=91.5]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=51.5]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=47.3]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=25.1]} {Human: ENSG00000158125, XDH, xanthine dehydrogenase, [Score=476, Expect=9e-146]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=471, Expect=4e-144]; ENSMUSG00000079554, Aox2, aldehyde oxidase 2, [Score=457, Expect=7e-139]; ENSMUSG00000063558, Aox1, aldehyde oxidase 1, [Score=456, Expect=1e-138]; ENSMUSG00000038242, Aox4, aldehyde oxidase 4, [Score=449, Expect=5e-136]} {Dmel: FBgn0267408, AOX1, Aldehyde oxidase 1, [Score=640, Expect=0.0]} {Celegans: WBGene00010083, xhd-1, [Score=485, Expect=1e-149]} {RNA1509_325, RNA1509_38160} {RNA1310_1603.1, RNA1509_38160} {RNA1509_38160, RNA815_224.2}
64. MligTC455_29045 127 2.65 Mlig455_056054

Neo: -

Age: -

Region-enriched R2: 4.858/0.00652

FZD5 2.877 - - 0.938 0.957 - 0.982 Mlig455_056054 {REF} {Length: 3655} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=389.0]; Fz domain [PF01392.24, score=85.2]} {Human: ENSG00000163251, FZD5, frizzled class receptor 5, [Score=554, Expect=0.0]} {Mouse: ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [Score=561, Expect=0.0]} {Dmel: FBgn0016797, fz2, frizzled 2, [Score=516, Expect=5e-176]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=368, Expect=3e-120]} {Smed: dd_Smed_v6_16571_0_1, dd_Smed_v6_16571_0_1, [Score=522, Expect=7e-178]} {RNA1509_35313} {RNA1310_9623.1} {RNA815_2562.1}
65. MligTC455_13154 28 0.59 Mlig455_007824

Neo: -

Age: -

2.869 - - 0.966 - 0.936 0.967 Mlig455_007824 {REF} {Length: 2457} {RNA1509_43477} {RNA1310_26398} {RNA815_11119}
66. MligTC455_52570 71 1.49 Mlig455_066071

Neo: -

Age: Up-Down-Up

2.866 - - - 0.934 0.952 0.980 Mlig455_066071 {REF} {Length: 2575} {Pfam: Hemingway/CFA97 [PF13879.8, score=54.6]; Annexin [PF00191.22, score=26.1]} {Mouse: ENSMUSG00000090336, Cfap97d2, CFAP97 domain containing 2, [Score=46.6, Expect=3e-06]} {Smed: dd_Smed_v6_2676_0_1, dd_Smed_v6_2676_0_1, [Score=70.1, Expect=2e-13]} {RNA1310_29320.1} {RNA815_54680}
67. MligTC455_29030 141 2.93 Mlig455_061986

Neo: -

Age: logFC(26M/2M)=-0.349

Region-enriched R2: 5.117/0.03372

FZD5 2.865 - - 0.945 0.954 - 0.966 Mlig455_061986 {REF} {Length: 3701} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=386.1]; Fz domain [PF01392.24, score=95.9]} {Human: ENSG00000163251, FZD5, frizzled class receptor 5, [Score=582, Expect=0.0]} {Mouse: ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [RH, Score=586, Expect=0.0]} {Dmel: FBgn0016797, fz2, frizzled 2, [Score=545, Expect=0.0]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=388, Expect=7e-127]} {Smed: dd_Smed_v6_16571_0_1, dd_Smed_v6_16571_0_1, [RH, Score=556, Expect=0.0]} {RNA1509_35313} {RNA1310_9623.1} {RNA815_2562.1}
68. MligTC455_18269 27 0.56 Mlig455_008658

Neo: -

Age: -

2.846 - - - 0.937 0.929 0.980 Mlig455_008658 {REF} {Length: 1290} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=19.1]} {RNA1509_25258} {RNA1310_4580, RNA1509_25258} {RNA1509_25258, RNA815_9496.1}
69. MligTC455_54338 49 1.02 Mlig455_056485

Neo: -

Age: Up-Down-Down

PKDREJ 2.846 - - - 0.952 0.928 0.966 Mlig455_056485 {REF} {Length: 11174} {Pfam: Polycystin cation channel [PF08016.14, score=290.0]; REJ domain [PF02010.17, score=90.7]; PLAT/LH2 domain [PF01477.25, score=67.3]; PKD domain [PF00801.22, score=47.7]; Ion transport protein [PF00520.33, score=40.1]; PKD domain [PF18911.2, score=29.8]; GPCR proteolysis site, GPS, motif [PF01825.23, score=27.4]; WSC domain [PF01822.21, score=27.0]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=280, Expect=1e-74]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=307, Expect=8e-83]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=151, Expect=3e-36]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [RH, Score=302, Expect=1e-81]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [RH, Score=1844, Expect=0.0]} {RNA1509_16432} {RNA1310_1236} {RNA815_2411}
70. MligTC455_14293 27 0.55 Mlig455_005699

Neo: -

Age: -

2.844 - - - 0.953 0.911 0.980 Mlig455_005699 {REF} {Length: 220} {NoTransDecoderORF} {RNA1509_35414} {RNA1310_4580}
71. MligTC455_18891 275 5.73 Mlig455_024941

Neo: -

Age: -

Region-enriched R2: 2.016/0.02450

2.844 - - - 0.875 0.992 0.977 Mlig455_024941 {REF} {Length: 394} {NoTransDecoderORF} {RNA1509_45136} {RNA1310_56753} {RNA815_28269}
72. MligTC455_53842 1222 25.46 Mlig455_023890

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.345

Region-enriched R2: 1.546/0.01667

2.842 - - - 0.898 0.970 0.974 Mlig455_023890 {REF} {Length: 1336} {RNA1509_15580} {RNA1310_22487.1} {RNA815_10676.1}
73. MligTC455_09472 23 0.47 Mlig455_059329

Neo: -

Age: -

NGB 2.841 - - 0.948 - 0.926 0.967 Mlig455_059329 {REF} {Length: 2110} {Pfam: Globin [PF00042.24, score=52.9]} {Human: ENSG00000165553, NGB, neuroglobin, [RH, Score=48.5, Expect=8e-07]} {Mouse: ENSMUSG00000021032, Ngb, neuroglobin, [RH, Score=50.4, Expect=1e-07]} {RNA1310_93460} {RNA815_18392}
74. MligTC455_28693 60 1.26 Mlig455_022354

Neo: -

Age: -

2.836 - - - 0.894 0.962 0.980 Mlig455_022354 {REF} {Length: 816} {Pfam: WSC domain [PF01822.21, score=53.0]; PAN domain [PF00024.28, score=20.6]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=48.1, Expect=2e-06]} {RNA1509_43359} {RNA1310_59466.1} {RNA815_19988}
75. MligTC455_27203 178 3.7 Mlig455_056778

Neo: -

Age: -

Region-enriched R5: 2.470/0.02695

ACTG1 2.835 - - - 0.915 0.976 0.944 Mlig455_056778 {REF} {Length: 10764} {Pfam: Actin [PF00022.21, score=469.5]; RIH domain [PF01365.23, score=52.7]; Integrase core domain [PF00665.28, score=48.1]; Inositol 1,4,5-trisphosphate/ryanodine receptor [PF08709.13, score=37.6]; MIR domain [PF02815.21, score=36.4]; RyR and IP3R Homology associated [PF08454.13, score=29.4]; Ion transport protein [PF00520.33, score=19.1]} {Human: ENSG00000184009, ACTG1, actin gamma 1, [Score=710, Expect=0.0]; ENSG00000075624, ACTB, actin beta, [Score=708, Expect=0.0]; ENSG00000107796, ACTA2, actin, alpha 2, smooth muscle, aorta, [Score=689, Expect=0.0]; ENSG00000159251, ACTC1, actin, alpha, cardiac muscle 1, [Score=689, Expect=0.0]; ENSG00000163017, ACTG2, actin, gamma 2, smooth muscle, enteric, [Score=689, Expect=0.0]; ENSG00000143632, ACTA1, actin, alpha 1, skeletal muscle, [Score=688, Expect=0.0]; ENSG00000169067, ACTBL2, actin, beta like 2, [Score=681, Expect=0.0]} {Mouse: ENSMUSG00000062825, Actg1, actin, gamma, cytoplasmic 1, [Score=710, Expect=0.0]; ENSMUSG00000029580, Actb, actin, beta, [Score=708, Expect=0.0]; ENSMUSG00000035783, Acta2, actin, alpha 2, smooth muscle, aorta, [Score=689, Expect=0.0]; ENSMUSG00000059430, Actg2, actin, gamma 2, smooth muscle, enteric, [Score=689, Expect=0.0]; ENSMUSG00000068614, Actc1, actin, alpha, cardiac muscle 1, [Score=689, Expect=0.0]; ENSMUSG00000031972, Acta1, actin, alpha 1, skeletal muscle, [Score=688, Expect=0.0]; ENSMUSG00000055194, Actbl2, actin, beta-like 2, [Score=687, Expect=0.0]} {Dmel: FBgn0000044, Act57B, Actin 57B, [Score=708, Expect=0.0]} {Celegans: WBGene00000065, act-3, Actin-1, [Score=711, Expect=0.0]} {Smed: dd_Smed_v6_3_0_1, dd_Smed_v6_3_0_1, [Score=702, Expect=0.0]} {RNA1509_59019} {RNA1310_34487} {RNA815_14388}
76. MligTC455_16729 75 1.57 Mlig455_013762

Neo: -

Age: Up-Down-Down

Region-enriched R4: 4.685/0.03582

2.834 - - - 0.966 0.889 0.979 Mlig455_013762 {REF} {Length: 2706} {Pfam: Glycine rich protein [PF12810.9, score=24.7]; PAN domain [PF00024.28, score=18.7]} {RNA1310_22079} {RNA815_24304}
77. MligTC455_43961 30 0.62 Mlig455_027626

Neo: -

Age: -

2.831 - - 0.924 0.924 - 0.983 Mlig455_027626 {REF} {Length: 602} {Pfam: PAN domain [PF00024.28, score=26.5]; PAN domain [PF14295.8, score=21.8]} {RNA1310_35396.1} {RNA815_23500}
78. MligTC455_51051 233 4.85 Mlig455_046293

Neo: -

Age: -

2.829 - - - 0.944 0.913 0.972 Mlig455_046293 {REF} {Length: 1585} {RNA1310_32253}
79. MligTC455_29913 199 4.14 Mlig455_027712, Mlig455_027722, Mlig455_027913

Neo: -

Age: -

ANK1, ANKRD36B 2.828 - - 0.912 - 0.961 0.955

Mlig455_027712 {REF} {Length: 1717} {RNA1509_21341} {RNA1310_7057.1} {RNA815_12060.1}

Mlig455_027722 {REF} {Length: 2267} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=67.4]; Ankyrin repeats (many copies) [PF13637.8, score=46.0]; Ankyrin repeats (many copies) [PF13857.8, score=32.7]; Ankyrin repeat [PF13606.8, score=27.7]; Ankyrin repeat [PF00023.32, score=22.3]} {Human: ENSG00000196912, ANKRD36B, ankyrin repeat domain 36B, [Score=66.2, Expect=2e-11]; ENSG00000106013, ANKRD7, ankyrin repeat domain 7, [Score=65.9, Expect=3e-11]; ENSG00000163046, ANKRD30BL, ankyrin repeat domain 30B like, [Score=65.5, Expect=4e-11]; ENSG00000180777, ANKRD30B, ankyrin repeat domain 30B, [Score=63.9, Expect=6e-10]} {Mouse: ENSMUSG00000029517, Ankrd7, ankyrin repeat domain 7, [Score=65.5, Expect=3e-11]; ENSMUSG00000106824, Gm7697, predicted gene 7697, [Score=63.2, Expect=3e-10]; ENSMUSG00000107280, Gm9495, predicted gene 9495, [Score=63.2, Expect=3e-10]; ENSMUSG00000063932, Poteg, POTE ankyrin domain family, member G, [Score=62.4, Expect=1e-09]} {Dmel: FBgn0043884, mask, multiple ankyrin repeats single KH domain, [Score=55.8, Expect=1e-07]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=54.7, Expect=2e-07]} {Smed: dd_Smed_v6_1432_0_3, dd_Smed_v6_1432_0_3, [Score=60.8, Expect=2e-09]} {RNA1509_21341} {RNA1310_7057.1} {RNA815_12060.1}

Mlig455_027913 {REF} {Length: 2198} {Pfam: Ankyrin repeats (many copies) [PF13857.8, score=37.7]; Ankyrin repeats (3 copies) [PF12796.9, score=33.6]; Ankyrin repeat [PF13606.8, score=28.5]; Ankyrin repeats (many copies) [PF13637.8, score=25.8]; Ankyrin repeat [PF00023.32, score=24.7]} {Human: ENSG00000029534, ANK1, ankyrin 1, [Score=48.1, Expect=2e-07]; ENSG00000134313, KIDINS220, kinase D interacting substrate 220, [Score=45.8, Expect=1e-06]} {Mouse: ENSMUSG00000031543, Ank1, ankyrin 1, erythroid, [Score=49.7, Expect=4e-08]} {Dmel: FBgn0027596, Kank, [Score=48.5, Expect=8e-08]} {Smed: dd_Smed_v6_29517_0_1, dd_Smed_v6_29517_0_1, [Score=45.1, Expect=8e-07]} {RNA1509_21341} {RNA1310_7057.2} {RNA815_12060.1}
80. MligTC455_18579 143 2.97 Mlig455_047208, Mlig455_048469

Neo: -

Age: -

GRIK2, GRIK3 2.827 - - - 0.905 0.941 0.981

Mlig455_047208 {REF} {Length: 5413} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=92.5]; Ligand-gated ion channel [PF00060.28, score=84.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=49.2]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=194, Expect=2e-50]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=193, Expect=5e-50]; ENSG00000105737, GRIK5, glutamate ionotropic receptor kainate type subunit 5, [Score=192, Expect=2e-49]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=192, Expect=2e-49]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=191, Expect=3e-49]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=194, Expect=1e-50]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=194, Expect=3e-50]; ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=191, Expect=2e-49]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=191, Expect=2e-49]; ENSMUSG00000003378, Grik5, glutamate receptor, ionotropic, kainate 5 (gamma 2), [Score=188, Expect=2e-48]} {Dmel: FBgn0038837, CG3822, [Score=185, Expect=9e-48]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=200, Expect=7e-53]} {Smed: dd_Smed_v6_17503_0_1, dd_Smed_v6_17503_0_1, [Score=341, Expect=5e-106]} {RNA1509_47157} {RNA1310_18671} {RNA815_30308}

Mlig455_048469 {REF} {Length: 3740} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=95.9]; Ligand-gated ion channel [PF00060.28, score=82.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=51.5]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=190, Expect=6e-50]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=187, Expect=5e-49]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=185, Expect=3e-48]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=184, Expect=1e-47]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=189, Expect=7e-50]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=187, Expect=6e-49]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=185, Expect=2e-48]; ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=183, Expect=9e-48]} {Dmel: FBgn0038837, CG3822, [Score=183, Expect=4e-48]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=183, Expect=3e-48]} {Smed: dd_Smed_v6_17503_0_1, dd_Smed_v6_17503_0_1, [Score=338, Expect=6e-108]} {RNA1509_47157} {RNA1310_18671} {RNA815_30308}
81. MligTC455_21721 1177 24.51 Mlig455_052943, Mlig455_053013

Neo: -

Age: -

TRPM3 2.822 - - - 0.958 0.941 0.923

Mlig455_052943 {REF} {Length: 4423} {TRANSSPLICED} {Pfam: SLOG in TRPM [PF18139.3, score=222.0]; SLOG in TRPM, prokaryote [PF18171.3, score=68.5]; Ion transport protein [PF00520.33, score=52.7]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [RH, Score=521, Expect=2e-158]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [RH, Score=522, Expect=1e-158]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=484, Expect=1e-149]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=362, Expect=8e-104]} {Smed: dd_Smed_v6_13119_0_1, dd_Smed_v6_13119_0_1, [Score=607, Expect=0.0]} {RNA1509_4847} {RNA1310_1801.1} {RNA815_652.1}

Mlig455_053013 {REF} {Length: 4421} {TRANSSPLICED} {Pfam: SLOG in TRPM [PF18139.3, score=222.1]; SLOG in TRPM, prokaryote [PF18171.3, score=68.5]; Ion transport protein [PF00520.33, score=53.1]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [RH, Score=517, Expect=8e-157]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [RH, Score=519, Expect=2e-157]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=482, Expect=8e-149]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=363, Expect=2e-104]} {Smed: dd_Smed_v6_13119_0_1, dd_Smed_v6_13119_0_1, [Score=605, Expect=0.0]} {RNA1509_4847} {RNA1310_1801.1, RNA1509_4847} {RNA1509_4847, RNA815_652.1}
82. MligTC455_41541 30 0.62 Mlig455_064895

Neo: -

Age: -

GLUL 2.82 - - - 0.930 0.910 0.980 Mlig455_064895 {REF} {Length: 1633} {Pfam: Glutamine synthetase, catalytic domain [PF00120.26, score=57.2]; Glutamine synthetase, beta-Grasp domain [PF03951.21, score=45.1]} {Human: ENSG00000135821, GLUL, glutamate-ammonia ligase, [RH, Score=503, Expect=4e-177]} {Mouse: ENSMUSG00000026473, Glul, glutamate-ammonia ligase (glutamine synthetase), [RH, Score=503, Expect=2e-179]} {Dmel: FBgn0001145, Gs2, Glutamine synthetase 2, [RH, Score=510, Expect=0.0]} {Celegans: WBGene00001604, gln-3, Glutamine synthetase, [RH, Score=511, Expect=0.0]} {Smed: dd_Smed_v6_896_0_1, dd_Smed_v6_896_0_1, [RH, Score=546, Expect=0.0]} {RNA1509_47000} {RNA1310_22329.1, RNA1509_47000} {RNA1509_47000, RNA815_4116.6}
83. MligTC455_31901 18 0.38 Mlig455_022355

Neo: -

Age: -

2.82 - - - 0.948 0.892 0.980 Mlig455_022355 {REF} {Length: 541} {Pfam: PAN domain [PF00024.28, score=19.0]} {RNA1310_125793} {RNA815_23776.1}
84. MligTC455_32445 285 5.93 Mlig455_041727, Mlig455_042282

Neo: -

Age: -

ANK2 2.82 - - - 0.914 0.966 0.940

Mlig455_041727 {REF} {Length: 4931} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=276.7]; Ankyrin repeats (many copies) [PF13637.8, score=238.3]; Ankyrin repeat [PF00023.32, score=223.0]; Ankyrin repeats (many copies) [PF13857.8, score=214.9]; Ankyrin repeat [PF13606.8, score=201.4]; Ion transport protein [PF00520.33, score=46.6]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=211, Expect=1e-54]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=290, Expect=2e-80]} {Dmel: FBgn0011747, Ank, Ankyrin, [Score=210, Expect=2e-54]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=489, Expect=7e-151]} {Smed: dd_Smed_v6_6201_0_2, dd_Smed_v6_6201_0_2, [RH, Score=745, Expect=0.0]} {RNA1509_18945} {RNA1310_1506.1, RNA1509_18945} {RNA1509_18945, RNA815_450.1}

Mlig455_042282 {REF} {Length: 4940} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=273.8]; Ankyrin repeats (many copies) [PF13637.8, score=232.4]; Ankyrin repeat [PF00023.32, score=218.4]; Ankyrin repeats (many copies) [PF13857.8, score=210.6]; Ankyrin repeat [PF13606.8, score=197.5]; Ion transport protein [PF00520.33, score=46.6]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=214, Expect=2e-55]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=204, Expect=1e-52]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=201, Expect=2e-51]} {Dmel: FBgn0011747, Ank, Ankyrin, [Score=205, Expect=6e-53]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=487, Expect=5e-150]} {Smed: dd_Smed_v6_6201_0_2, dd_Smed_v6_6201_0_2, [RH, Score=736, Expect=0.0]} {RNA1509_18945} {RNA1310_1506.1} {RNA815_8298}
85. MligTC455_40387 28 0.59 Mlig455_019391

Neo: -

Age: Up-Down-Down

2.819 - - - 0.934 0.902 0.983 Mlig455_019391 {REF} {Length: 2094} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=34.2]} {Smed: dd_Smed_v6_41498_0_1, dd_Smed_v6_41498_0_1, [Score=146, Expect=1e-37]} {RNA1310_29891} {RNA815_15562}
86. MligTC455_17568 33 0.68 Mlig455_059349, Mlig455_065584

Neo: -

Age: -

2.818 - - - 0.884 0.954 0.980

Mlig455_059349 {REF} {Length: 1132} {RNA1509_24218} {RNA1310_25312.1} {RNA815_12390}

Mlig455_065584 {REF} {Length: 1132} {RNA1509_24218} {RNA1310_25312.1} {RNA815_12390}
87. MligTC455_22688 18 0.37 Mlig455_030413

Neo: -

Age: -

GRIK3 2.817 - - 0.905 0.949 - 0.963 Mlig455_030413 {REF} {Length: 3851} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=76.0]; Ligand-gated ion channel [PF00060.28, score=51.9]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=45.7]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=158, Expect=1e-40]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=153, Expect=7e-39]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=149, Expect=7e-38]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=149, Expect=6e-38]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=148, Expect=2e-37]} {Dmel: FBgn0039916, Ekar, Eye-enriched kainate receptor, [Score=142, Expect=1e-35]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=132, Expect=1e-32]} {Smed: dd_Smed_v6_4267_0_3, dd_Smed_v6_4267_0_3, [Score=149, Expect=5e-38]} {RNA1310_20394.1} {RNA815_45848}
88. MligTC455_21502 36 0.75 Mlig455_018529

Neo: -

Age: -

Region-enriched R2: 5.380/0.01311

2.816 - - 0.920 - 0.942 0.954 Mlig455_018529 {REF} {Length: 1004} {Pfam: Fas apoptotic inhibitory molecule (FAIM1) [PF06905.15, score=43.7]} {Mouse: ENSMUSG00000032463, Faim, Fas apoptotic inhibitory molecule, [Score=54.7, Expect=2e-09]} {Smed: dd_Smed_v6_4798_0_1, dd_Smed_v6_4798_0_1, [RH, Score=75.1, Expect=7e-18]} {RNA1310_42034} {RNA815_19884}
89. MligTC455_41226 44 0.92 Mlig455_019357, Mlig455_059122

Neo: -

Age: -

GALNT1 2.816 - - - 0.950 0.890 0.976

Mlig455_019357 {REF} {Length: 1606} {Pfam: Glycosyl transferase family 2 [PF00535.28, score=97.5]; Glycosyltransferase like family 2 [PF13641.8, score=38.9]; N-terminal domain of galactosyltransferase [PF02709.16, score=29.1]; Glycosyltransferase like family 2 [PF10111.11, score=18.5]} {Human: ENSG00000141429, GALNT1, polypeptide N-acetylgalactosaminyltransferase 1, [Score=318, Expect=2e-103]; ENSG00000139629, GALNT6, polypeptide N-acetylgalactosaminyltransferase 6, [Score=311, Expect=4e-100]; ENSG00000257594, GALNT4, polypeptide N-acetylgalactosaminyltransferase 4, [Score=305, Expect=3e-98]; ENSG00000259075, POC1B-GALNT4, POC1B-GALNT4 readthrough, [Score=305, Expect=3e-98]} {Mouse: ENSMUSG00000000420, Galnt1, polypeptide N-acetylgalactosaminyltransferase 1, [Score=316, Expect=1e-102]; ENSMUSG00000037280, Galnt6, polypeptide N-acetylgalactosaminyltransferase 6, [Score=308, Expect=9e-99]; ENSMUSG00000060988, Galnt13, polypeptide N-acetylgalactosaminyltransferase 13, [Score=302, Expect=3e-97]} {Dmel: FBgn0050463, CG30463, [Score=345, Expect=5e-113]} {Celegans: WBGene00001630, gly-5, Polypeptide N-acetylgalactosaminyltransferase 5, [Score=350, Expect=3e-115]} {Smed: dd_Smed_v6_8580_0_1, dd_Smed_v6_8580_0_1, [Score=353, Expect=1e-117]} {RNA1310_25598} {RNA815_36943}

Mlig455_059122 {REF} {Length: 2150} {Pfam: Glycosyl transferase family 2 [PF00535.28, score=96.4]; Glycosyltransferase like family 2 [PF13641.8, score=35.9]; N-terminal domain of galactosyltransferase [PF02709.16, score=29.5]} {Human: ENSG00000141429, GALNT1, polypeptide N-acetylgalactosaminyltransferase 1, [Score=313, Expect=2e-101]; ENSG00000139629, GALNT6, polypeptide N-acetylgalactosaminyltransferase 6, [Score=307, Expect=2e-98]; ENSG00000257594, GALNT4, polypeptide N-acetylgalactosaminyltransferase 4, [Score=300, Expect=6e-96]; ENSG00000259075, POC1B-GALNT4, POC1B-GALNT4 readthrough, [Score=299, Expect=7e-96]; ENSG00000144278, GALNT13, polypeptide N-acetylgalactosaminyltransferase 13, [Score=298, Expect=1e-95]} {Mouse: ENSMUSG00000000420, Galnt1, polypeptide N-acetylgalactosaminyltransferase 1, [Score=311, Expect=1e-100]; ENSMUSG00000037280, Galnt6, polypeptide N-acetylgalactosaminyltransferase 6, [Score=305, Expect=1e-97]; ENSMUSG00000060988, Galnt13, polypeptide N-acetylgalactosaminyltransferase 13, [Score=298, Expect=8e-96]; ENSMUSG00000026994, Galnt3, polypeptide N-acetylgalactosaminyltransferase 3, [Score=296, Expect=5e-94]; ENSMUSG00000026828, Galnt5, polypeptide N-acetylgalactosaminyltransferase 5, [Score=296, Expect=2e-91]} {Dmel: FBgn0050463, CG30463, [Score=340, Expect=3e-111]} {Celegans: WBGene00001630, gly-5, Polypeptide N-acetylgalactosaminyltransferase 5, [Score=344, Expect=3e-113]} {Smed: dd_Smed_v6_8580_0_1, dd_Smed_v6_8580_0_1, [Score=350, Expect=3e-116]} {RNA1310_25598} {RNA815_36943}
90. MligTC455_19908 490 10.21 Mlig455_047266, Mlig455_047318, Mlig455_069346

Neo: -

Age: logFC(26M/2M)=0.566

2.815 - - - 0.920 0.910 0.985

Mlig455_047266 {REF} {Length: 1728} {Pfam: Glycine rich protein [PF12810.9, score=49.4]} {RNA1509_28009} {RNA1310_17226} {RNA815_32720}

Mlig455_047318 {REF} {Length: 2268} {Pfam: Glycine rich protein [PF12810.9, score=36.7]} {RNA1509_28009} {RNA1310_17226, RNA1509_28009} {RNA1509_28009, RNA815_32720}

Mlig455_069346 {REF} {Length: 1953} {Pfam: Glycine rich protein [PF12810.9, score=31.6]} {RNA1509_28009} {RNA1310_17226} {RNA815_32720}
91. MligTC455_14842 21 0.45 Mlig455_041074

Neo: -

Age: -

2.814 - - - 0.926 0.916 0.972 Mlig455_041074 {REF} {Length: 1383} {RNA1310_60383} {RNA815_48502}
92. MligTC455_31163 72 1.51 Mlig455_045625

Neo: -

Age: Up-Down-Down

2.814 - - - 0.888 0.955 0.971 Mlig455_045625 {REF} {Length: 1957} {RNA1509_21720} {RNA1310_14760, RNA1509_21720} {RNA1509_21720, RNA815_24583}
93. MligTC455_46395 870 18.13 Mlig455_069471

Neo: -

Age: logFC(26M/2M)=0.458

PKD2 2.814 - - - 0.953 0.897 0.964 Mlig455_069471 {REF} {Length: 3122} {TRANSSPLICED} {Pfam: Polycystin cation channel [PF08016.14, score=487.8]; Ion transport protein [PF00520.33, score=93.3]; EF hand [PF00036.34, score=32.7]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=21.3]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=753, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=750, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=323, Expect=1e-96]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=387, Expect=8e-123]} {Smed: dd_Smed_v6_13327_0_1, dd_Smed_v6_13327_0_1, [RH, Score=769, Expect=0.0]} {RNA1509_13522} {RNA1310_21296.2} {RNA815_3158.1}
94. MligTC455_17429 31 0.65 Mlig455_007460

Neo: -

Age: -

IFT27 2.813 - - 0.952 0.939 - 0.922 Mlig455_007460 {REF} {Length: 970} {Pfam: Ras family [PF00071.24, score=120.4]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=54.3]} {Human: ENSG00000100360, IFT27, intraflagellar transport 27, [Score=123, Expect=3e-34]} {Mouse: ENSMUSG00000016637, Ift27, intraflagellar transport 27, [Score=130, Expect=3e-37]} {Dmel: FBgn0015795, Rab7, [Score=84.7, Expect=1e-19]} {Celegans: WBGene00004271, rab-7, RAB family, [Score=85.1, Expect=7e-20]} {Smed: dd_Smed_v6_11026_0_1, dd_Smed_v6_11026_0_1, [Score=122, Expect=3e-34]} {RNA1310_14163} {RNA815_25254}
95. MligTC455_18586 93 1.93 Mlig455_020226

Neo: -

Age: Down-Down-Up

2.811 - - - 0.901 0.952 0.958 Mlig455_020226 {REF} {Length: 1261} {RNA1310_64121} {RNA815_32233}
96. MligTC455_14715 31 0.65 Mlig455_043609

Neo: -

Age: -

ANGPTL1 2.809 - - - 0.874 0.956 0.979 Mlig455_043609 {REF} {Length: 1252} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=154.2]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=131, Expect=2e-34]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=128, Expect=2e-33]; ENSG00000085265, FCN1, ficolin 1, [Score=128, Expect=2e-34]; ENSG00000160339, FCN2, ficolin 2, [Score=125, Expect=5e-34]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=134, Expect=1e-35]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=129, Expect=7e-34]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=128, Expect=2e-33]} {Dmel: FBgn0033312, CG8642, [RH, Score=122, Expect=1e-31]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=112, Expect=7e-28]} {RNA1509_26827} {RNA1310_31596.2} {RNA815_17173.3}
97. MligTC455_41324 401 8.35 Mlig455_024997

Neo: -

Age: Up-Down-Down

CCDC151 2.809 - - - 0.889 0.957 0.963 Mlig455_024997 {REF} {Length: 2376} {TRANSSPLICED} {Human: ENSG00000198003, CCDC151, coiled-coil domain containing 151, [Score=251, Expect=5e-75]} {Mouse: ENSMUSG00000039632, Ccdc151, coiled-coil domain containing 151, [Score=261, Expect=4e-79]} {Dmel: FBgn0036219, CCDC151, Coiled-coil domain containing protein 151, [Score=111, Expect=2e-25]} {Smed: dd_Smed_v6_4526_0_1, dd_Smed_v6_4526_0_1, [Score=463, Expect=3e-158]} {RNA1509_18758} {RNA1310_9513.1, RNA1509_18758} {RNA1509_18758, RNA815_13766}
98. MligTC455_48986 511 10.64 Mlig455_017301

Neo: -

Age: Down-Up-Down

TRPM2 2.808 - - - 0.912 0.956 0.940 Mlig455_017301 {REF} {Length: 4476} {Pfam: SLOG in TRPM [PF18139.3, score=216.0]; SLOG in TRPM, prokaryote [PF18171.3, score=64.9]; Ion transport protein [PF00520.33, score=58.5]} {Human: ENSG00000142185, TRPM2, transient receptor potential cation channel subfamily M member 2, [Score=420, Expect=4e-123]} {Mouse: ENSMUSG00000009292, Trpm2, transient receptor potential cation channel, subfamily M, member 2, [Score=441, Expect=2e-130]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=293, Expect=2e-81]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=247, Expect=3e-66]} {Smed: dd_Smed_v6_13119_0_1, dd_Smed_v6_13119_0_1, [RH, Score=627, Expect=0.0]} {RNA1509_8528} {RNA1310_1728.1} {RNA815_888}
99. MligTC455_50146 37 0.77 Mlig455_050983

Neo: -

Age: -

NPSR1 2.808 - - 0.929 - 0.907 0.972 Mlig455_050983 {REF} {Length: 1326} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=105.5]} {Human: ENSG00000187258, NPSR1, neuropeptide S receptor 1, [Score=63.5, Expect=1e-10]} {Mouse: ENSMUSG00000029255, Gnrhr, gonadotropin releasing hormone receptor, [Score=66.6, Expect=4e-12]; ENSMUSG00000044014, Npy5r, neuropeptide Y receptor Y5, [Score=65.5, Expect=3e-11]} {Dmel: FBgn0036278, CrzR, Corazonin receptor, [Score=72.8, Expect=1e-13]} {Celegans: WBGene00013642, daf-38, G-protein coupled receptor daf-38, [Score=65.5, Expect=1e-11]} {Smed: dd_Smed_v6_75337_0_1, dd_Smed_v6_75337_0_1, [Score=66.6, Expect=2e-12]} {RNA1310_64751.2}
100. MligTC455_53844 1403 29.24 Mlig455_051626

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.540

2.808 - - - 0.897 0.966 0.945 Mlig455_051626 {REF} {Length: 1671} {RNA1509_15580} {RNA1310_24090} {RNA815_10676.2}

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