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Results for MligTC455_20353

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_20353 17917 373.27 Mlig455_013260, Mlig455_013275, Mlig455_013349

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.424

Region-enriched R3: 2.278/0.00008
Region-enriched R4: 1.727/0.01391

Mlig455_013260 {REF} {Length: 1502} {RNA1509_60036, RNA1509_670} {RNA1310_18395, RNA1509_60036} {RNA1509_60036, RNA815_8767}

Mlig455_013275 {REF} {Length: 1323} {RNA1509_670} {RNA1310_18395} {RNA815_8767}

Mlig455_013349 {REF} {Length: 1540} {RNA1509_51207, RNA1509_57783, RNA1509_670} {RNA1310_18395, RNA1509_51207, RNA1509_57783, RNA1509_670} {RNA1509_51207, RNA1509_57783, RNA1509_670, RNA815_8767}

Cumulative graph for MligTC455_20353

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.816 8.534 0.22330 0.86713
RegionR2 -1.601 8.534 0.01245 0.11560
RegionR3 2.278 8.534 0.00000 0.00008
RegionR4 1.727 8.534 0.00145 0.01391
RegionR5 1.249 8.534 0.00823 0.05011
RegionR6 1.097 8.534 0.02905 0.31405
RegionR7 -2.031 8.534 0.00131 0.04212
RegionR8 -1.904 8.534 0.00532 0.13122

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 1.322 8.534 0.07904 0.77084
RegenerationR2 1.397 8.534 0.04904 0.36600
RegenerationR3 0.418 8.534 0.54109 0.87824
RegenerationR4 0.869 8.534 0.21250 0.65987
RegenerationR5 1.401 8.534 0.03972 0.32847
RegenerationR6 1.297 8.534 0.06291 0.31498
RegenerationBL 0.817 8.534 0.15824 0.47636
RegenerationTP 1.89 8.534 0.00201 0.07278


Genes with expression patterns similar to MligTC455_20353

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_20353 17917 373.27 Mlig455_013260, Mlig455_013275, Mlig455_013349

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.424

Region-enriched R3: 2.278/0.00008
Region-enriched R4: 1.727/0.01391

6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_013260 {REF} {Length: 1502} {RNA1509_60036, RNA1509_670} {RNA1310_18395, RNA1509_60036} {RNA1509_60036, RNA815_8767}

Mlig455_013275 {REF} {Length: 1323} {RNA1509_670} {RNA1310_18395} {RNA815_8767}

Mlig455_013349 {REF} {Length: 1540} {RNA1509_51207, RNA1509_57783, RNA1509_670} {RNA1310_18395, RNA1509_51207, RNA1509_57783, RNA1509_670} {RNA1509_51207, RNA1509_57783, RNA1509_670, RNA815_8767}
2. MligTC455_38724 5697 118.69 Mlig455_045051

Neo: -

Age: logFC(26M/2M)=-0.423

Region-enriched R3: 1.948/0.00202

PANK4 5.165 0.708 0.895 0.897 0.790 0.964 0.911 Mlig455_045051 {REF} {Length: 2009} {Pfam: Fumble [PF03630.16, score=127.5]} {Human: ENSG00000157881, PANK4, pantothenate kinase 4, [Score=112, Expect=2e-26]; ENSG00000273494, PANK4, pantothenate kinase 4, [Score=112, Expect=2e-26]} {Mouse: ENSMUSG00000029056, Pank4, pantothenate kinase 4, [Score=102, Expect=2e-23]} {Dmel: FBgn0011205, fbl, fumble, [Score=86.7, Expect=1e-18]} {Celegans: WBGene00004068, pnk-1, PaNtothenate Kinase, [Score=82.4, Expect=3e-17]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [RH, Score=225, Expect=1e-70]} {RNA1509_11373, RNA1509_768} {RNA1310_14353, RNA1509_11373} {RNA1509_11373, RNA815_1414}
3. MligTC455_15678 9353 194.86 Mlig455_044843

Neo: -

Age: -

Region-enriched R3: 2.225/0.00001

MOXD1 5.038 0.764 0.834 0.779 0.851 0.834 0.976 Mlig455_044843 {REF} {Length: 2852} {Pfam: Copper type II ascorbate-dependent monooxygenase, N-terminal domain [PF01082.22, score=86.4]; Copper type II ascorbate-dependent monooxygenase, C-terminal domain [PF03712.17, score=60.8]} {Human: ENSG00000079931, MOXD1, monooxygenase DBH like 1, [Score=111, Expect=4e-25]; ENSG00000123454, DBH, dopamine beta-hydroxylase, [Score=107, Expect=1e-23]} {Mouse: ENSMUSG00000020000, Moxd1, monooxygenase, DBH-like 1, [Score=115, Expect=2e-26]; ENSMUSG00000000889, Dbh, dopamine beta hydroxylase, [Score=112, Expect=1e-25]} {Dmel: FBgn0010329, Tbh, Tyramine beta hydroxylase, [Score=122, Expect=7e-29]} {Celegans: WBGene00006541, tbh-1, Tyramine beta-hydroxylase, [Score=105, Expect=1e-23]} {Smed: dd_Smed_v6_42610_0_1, dd_Smed_v6_42610_0_1, [Score=116, Expect=3e-28]} {RNA1509_19571, RNA1509_21722, RNA1509_28470, RNA1509_33241, RNA1509_57451, RNA1509_8119, RNA1509_8271, RNA1509_893} {RNA1310_9962.1, RNA1509_19571, RNA1509_21722, RNA1509_28470, RNA1509_33241, RNA1509_57451, RNA1509_8119, RNA1509_8271, RNA1509_893} {RNA1509_19571, RNA1509_21722, RNA1509_28470, RNA1509_33241, RNA1509_57451, RNA1509_8119, RNA1509_8271, RNA1509_893, RNA815_3379.1}
4. MligTC455_45589 8445 175.93 Mlig455_060231

Neo: -

Age: Up-Down-Down

Region-enriched R3: 2.105/0.00005

MRC1 4.444 - 0.952 0.942 0.771 0.818 0.961 Mlig455_060231 {REF} {Length: 6599} {Pfam: Lectin C-type domain [PF00059.23, score=668.9]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=86.8]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [RH, Score=514, Expect=1e-153]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [RH, Score=487, Expect=3e-144]} {Dmel: FBgn0035199, tfc, triforce, [Score=57.4, Expect=1e-08]} {Celegans: WBGene00020191, clec-53, C-type LECtin, [RH, Score=103, Expect=2e-23]} {Smed: dd_Smed_v6_3193_0_2, dd_Smed_v6_3193_0_2, [Score=207, Expect=7e-54]} {RNA1509_14934, RNA1509_169, RNA1509_3659, RNA1509_3870} {RNA1310_579, RNA1509_14934, RNA1509_169, RNA1509_3659, RNA1509_3870} {RNA1509_14934, RNA1509_169, RNA1509_3659, RNA1509_3870, RNA815_112.1}
5. MligTC455_49519 17930 373.55 Mlig455_030984

Neo: -

Age: logFC(26M/2M)=0.549

Region-enriched R3: 2.084/0.00003

HPGDS 4.369 0.835 0.811 0.866 - 0.890 0.967 Mlig455_030984 {REF} {Length: 859} {Pfam: Glutathione S-transferase, C-terminal domain [PF14497.8, score=61.6]; Glutathione S-transferase, N-terminal domain [PF02798.22, score=46.9]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=28.2]} {Human: ENSG00000163106, HPGDS, hematopoietic prostaglandin D synthase, [RH, Score=106, Expect=9e-28]} {Mouse: ENSMUSG00000029919, Hpgds, hematopoietic prostaglandin D synthase, [RH, Score=93.6, Expect=4e-23]} {Dmel: FBgn0010226, GstS1, Glutathione S transferase S1, [Score=90.1, Expect=2e-21]} {Celegans: WBGene00001753, gst-5, Probable glutathione S-transferase 5, [RH, Score=112, Expect=3e-30]} {Smed: dd_Smed_v6_20_0_1, dd_Smed_v6_20_0_1, [RH, Score=187, Expect=8e-60]} {RNA1509_12904, RNA1509_271, RNA1509_888} {RNA1310_36360, RNA1509_12904, RNA1509_888} {RNA1509_12904, RNA1509_888, RNA815_14903.1}
6. MligTC455_41984 5794 120.71 Mlig455_070257

Neo: -

Age: logFC(26M/2M)=0.384

Region-enriched R3: 1.830/0.00014
Region-enriched R4: 1.696/0.00265
Region-enriched R6: 1.511/0.01084
Region-enriched R5: 1.493/0.00157

BHMT 4.334 - 0.888 0.776 0.846 0.851 0.973 Mlig455_070257 {REF} {Length: 2300} {Pfam: Homocysteine S-methyltransferase [PF02574.18, score=161.5]} {Human: ENSG00000145692, BHMT, betaine--homocysteine S-methyltransferase, [RH, Score=543, Expect=0.0]} {Mouse: ENSMUSG00000074768, Bhmt, betaine-homocysteine methyltransferase, [RH, Score=548, Expect=0.0]; ENSMUSG00000069324, Gm5096, predicted gene 5096, [RH, Score=548, Expect=0.0]} {Smed: dd_Smed_v6_873_0_1, dd_Smed_v6_873_0_1, [RH, Score=555, Expect=0.0]} {RNA1509_10637, RNA1509_54311, RNA1509_9980} {RNA1310_18981.1, RNA1509_54311, RNA1509_9980} {RNA1509_54311, RNA1509_9980, RNA815_5900.2}
7. MligTC455_49658 3392 70.66 Mlig455_011590

Neo: -

Age: -

Region-enriched R3: 1.949/0.00002

3.598 - 0.921 - 0.887 0.812 0.978 Mlig455_011590 {REF} {Length: 2376} {RNA1509_3964} {RNA1310_32368} {RNA815_14237.1}
8. MligTC455_34844 2198 45.79 Mlig455_023760

Neo: -

Age: logFC(26M/2M)=0.545

Region-enriched R3: 1.526/0.03191

CYP2J2 3.525 - 0.917 0.836 0.800 0.972 - Mlig455_023760 {REF} {Length: 2332} {Pfam: Cytochrome P450 [PF00067.24, score=323.6]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=272, Expect=4e-85]} {Mouse: ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=275, Expect=2e-86]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=267, Expect=2e-83]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [RH, Score=263, Expect=2e-81]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=234, Expect=3e-70]} {Celegans: WBGene00018413, cyp-33C4, CYtochrome P450 family, [RH, Score=259, Expect=1e-80]} {Smed: dd_Smed_v6_2351_0_1, dd_Smed_v6_2351_0_1, [Score=265, Expect=6e-83]} {RNA1509_5390} {RNA1310_15059, RNA1509_5390} {RNA1509_5390, RNA815_5935.1}
9. MligTC455_15686 5588 116.41 Mlig455_011058

Neo: -

Age: -

Region-enriched R3: 1.651/0.01200
Region-enriched R5: 1.436/0.01547

CRABP2 3.405 - 0.760 0.954 - 0.827 0.864 Mlig455_011058 {REF} {Length: 857} {Pfam: Lipocalin / cytosolic fatty-acid binding protein family [PF00061.25, score=54.9]; Lipocalin / cytosolic fatty-acid binding protein family [PF14651.8, score=29.1]} {Human: ENSG00000143320, CRABP2, cellular retinoic acid binding protein 2, [Score=95.5, Expect=1e-25]; ENSG00000170323, FABP4, fatty acid binding protein 4, [Score=91.7, Expect=3e-24]; ENSG00000121769, FABP3, fatty acid binding protein 3, [Score=91.3, Expect=4e-24]} {Mouse: ENSMUSG00000004885, Crabp2, cellular retinoic acid binding protein II, [Score=95.9, Expect=5e-26]; ENSMUSG00000027533, Fabp5, fatty acid binding protein 5, epidermal, [Score=93.2, Expect=5e-25]; ENSMUSG00000028773, Fabp3, fatty acid binding protein 3, muscle and heart, [Score=92.4, Expect=1e-24]} {Dmel: FBgn0037913, fabp, fatty acid binding protein, [Score=76.6, Expect=1e-18]} {Celegans: WBGene00002257, lbp-5, Fatty acid-binding protein homolog 5, [Score=100, Expect=6e-28]} {Smed: dd_Smed_v6_271_0_1, dd_Smed_v6_271_0_1, [RH, Score=102, Expect=6e-29]} {RNA1509_23333, RNA1509_23783, RNA1509_29966, RNA1509_3321, RNA1509_6404} {RNA1310_38135.2, RNA1509_23333, RNA1509_23783, RNA1509_29966, RNA1509_3321, RNA1509_6404} {RNA1509_23333, RNA1509_23783, RNA1509_29966, RNA1509_3321, RNA1509_6404, RNA815_30164}
10. MligTC455_32555 3333 69.45 Mlig455_023825

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.526

Region-enriched R3: 1.882/0.00000
Region-enriched R4: 1.126/0.03622

PRSS12 3.4 - - 0.768 0.809 0.951 0.872 Mlig455_023825 {REF} {Length: 4714} {Pfam: Trypsin [PF00089.28, score=216.2]; Scavenger receptor cysteine-rich domain [PF00530.20, score=95.2]; Low-density lipoprotein receptor domain class A [PF00057.20, score=94.1]; Scavenger receptor cysteine-rich domain [PF15494.8, score=25.1]; Trypsin-like peptidase domain [PF13365.8, score=20.3]; Nematode trypsin-6-like family [PF03761.17, score=18.5]} {Human: ENSG00000164099, PRSS12, serine protease 12, [Score=220, Expect=4e-60]} {Mouse: ENSMUSG00000027978, Prss12, protease, serine 12 neurotrypsin (motopsin), [Score=212, Expect=3e-58]} {Dmel: FBgn0023479, teq, Tequila, [Score=286, Expect=1e-81]} {Celegans: WBGene00006620, svh-1, HGF/MSP/plasminogen-like protein, [RH, Score=191, Expect=2e-50]} {Smed: dd_Smed_v6_790_0_1, dd_Smed_v6_790_0_1, [Score=489, Expect=7e-158]} {RNA1509_337} {RNA1310_1502.2} {RNA815_422}
11. MligTC455_51880 13248 275.99 Mlig455_059444

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-3.002

Region-enriched R3: 1.727/0.04203

3.385 - 0.865 0.834 0.985 0.701 - Mlig455_059444 {REF} {Length: 1115} {RNA1509_16825, RNA1509_20241, RNA1509_31277, RNA1509_40483, RNA1509_410, RNA1509_7504} {RNA1310_33614.1, RNA1509_16825, RNA1509_20241, RNA1509_31277, RNA1509_40483, RNA1509_410, RNA1509_7504} {RNA1509_16825, RNA1509_20241, RNA1509_31277, RNA1509_40483, RNA1509_410, RNA1509_7504, RNA815_18624}
12. MligTC455_27625 5733 119.44 Mlig455_018765

Neo: -

Age: Down-Down-Up

Region-enriched R3: 1.886/0.00051

MATN2 3.367 - 0.755 - 0.890 0.953 0.769 Mlig455_018765 {REF} {Length: 2544} {Pfam: von Willebrand factor type A domain [PF00092.30, score=235.9]; von Willebrand factor type A domain [PF13519.8, score=103.0]; von Willebrand factor type A domain [PF13768.8, score=54.3]; VWA domain containing CoxE-like protein [PF05762.16, score=36.8]; Protein of unknown function (DUF1194) [PF06707.13, score=35.1]} {Human: ENSG00000132561, MATN2, matrilin 2, [Score=97.1, Expect=3e-20]} {Mouse: ENSMUSG00000040533, Matn1, matrilin 1, cartilage matrix protein, [Score=105, Expect=1e-23]} {Celegans: WBGene00003482, mua-3, Transmembrane cell adhesion receptor mua-3, [Score=82.0, Expect=8e-16]} {Smed: dd_Smed_v6_2674_0_1, dd_Smed_v6_2674_0_1, [Score=92.0, Expect=3e-19]} {RNA1509_3165} {RNA1310_8996, RNA1509_3165} {RNA1509_3165, RNA815_2915.1}
13. MligTC455_40682 2549 53.1 Mlig455_013284, Mlig455_035928

Neo: -

Age: -

Region-enriched R3: 1.724/0.00155
Region-enriched R4: 1.452/0.02174
Region-enriched R5: 1.104/0.04518

3.313 - 0.776 0.740 - 0.812 0.985

Mlig455_013284 {REF} {Length: 2073} {Pfam: Tctex-1 family [PF03645.15, score=31.9]} {Mouse: ENSMUSG00000079710, Gm3448, predicted gene 3448, [Score=50.1, Expect=3e-07]; ENSMUSG00000079707, Tcte3, t-complex-associated testis expressed 3, [Score=50.1, Expect=3e-07]; ENSMUSG00000116780, Gm3417, predicted gene 3417, [Score=48.9, Expect=6e-07]} {Smed: dd_Smed_v6_12108_0_1, dd_Smed_v6_12108_0_1, [Score=57.8, Expect=2e-10]} {RNA1509_11021, RNA1509_22678} {RNA1310_29221, RNA1509_11021, RNA1509_22678} {RNA1509_11021, RNA1509_22678, RNA815_16910}

Mlig455_035928 {REF} {Length: 1424} {Pfam: Tctex-1 family [PF03645.15, score=31.7]} {Mouse: ENSMUSG00000079707, Tcte3, t-complex-associated testis expressed 3, [Score=49.7, Expect=4e-07]; ENSMUSG00000079710, Gm3448, predicted gene 3448, [Score=49.7, Expect=4e-07]; ENSMUSG00000116780, Gm3417, predicted gene 3417, [Score=48.5, Expect=9e-07]} {Smed: dd_Smed_v6_12108_0_1, dd_Smed_v6_12108_0_1, [Score=58.5, Expect=1e-10]} {RNA1509_11021, RNA1509_38233} {RNA1310_29221, RNA1509_38233} {RNA1509_38233, RNA815_16910}
14. MligTC455_47632 1274 26.54 Mlig455_021530

Neo: -

Age: Down-Up-Up

Region-enriched R4: 2.128/0.00004
Region-enriched R3: 1.330/0.02022
Region-enriched R5: 1.147/0.01776

3.165 - - 0.707 0.721 0.779 0.958 Mlig455_021530 {REF} {Length: 949} {Pfam: Universal stress protein family [PF00582.28, score=103.9]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=130, Expect=1e-39]} {RNA1509_13699, RNA1509_6559} {RNA1310_39993, RNA1509_13699, RNA1509_6559} {RNA1509_13699, RNA1509_6559, RNA815_18311}
15. MligTC455_41416 8205 170.94 Mlig455_021854

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.738

Region-enriched R3: 1.023/0.03980

Regeneration-depleted BL: -2.050
Regeneration-depleted R3: -1.772

2.753 - 0.879 0.920 - - 0.954 Mlig455_021854 {REF} {Length: 1653} {TRANSSPLICED} {RNA1509_10112, RNA1509_505} {RNA1310_27932, RNA1509_10112, RNA1509_505} {RNA1509_10112, RNA1509_505, RNA815_11765.1}
16. MligTC455_26854 3943 82.15 Mlig455_045731, Mlig455_045775, Mlig455_045787

Neo: -

Age: Down-Down-Up

GLIPR2 2.674 - - - 0.887 0.832 0.955

Mlig455_045731 {REF} {Length: 332} {Human: ENSG00000122694, GLIPR2, GLI pathogenesis related 2, [Score=42.7, Expect=9e-06]} {Mouse: ENSMUSG00000028480, Glipr2, GLI pathogenesis-related 2, [Score=46.6, Expect=4e-07]} {Smed: dd_Smed_v6_2081_0_1, dd_Smed_v6_2081_0_1, [Score=60.1, Expect=6e-12]} {RNA1509_18768} {RNA1310_32519} {RNA815_6130}

Mlig455_045775 {REF} {Length: 2034} {Pfam: Cysteine-rich secretory protein family [PF00188.28, score=111.7]} {Human: ENSG00000122694, GLIPR2, GLI pathogenesis related 2, [Score=110, Expect=1e-28]} {Mouse: ENSMUSG00000028480, Glipr2, GLI pathogenesis-related 2, [Score=107, Expect=1e-27]} {Dmel: FBgn0054049, CG34049, [Score=84.7, Expect=4e-18]} {Celegans: WBGene00008604, F09B9.5, [Score=72.4, Expect=8e-15]} {Smed: dd_Smed_v6_2081_0_1, dd_Smed_v6_2081_0_1, [RH, Score=298, Expect=1e-98]} {RNA1509_18768, RNA1509_4485, RNA1509_588} {RNA1310_16722.1, RNA1509_18768, RNA1509_4485, RNA1509_588} {RNA1509_18768, RNA1509_4485, RNA1509_588, RNA815_6130}

Mlig455_045787 {REF} {Length: 339} {Human: ENSG00000122694, GLIPR2, GLI pathogenesis related 2, [Score=43.1, Expect=9e-06]} {Mouse: ENSMUSG00000028480, Glipr2, GLI pathogenesis-related 2, [Score=46.6, Expect=3e-07]} {Smed: dd_Smed_v6_2081_0_1, dd_Smed_v6_2081_0_1, [Score=60.1, Expect=7e-12]} {RNA1509_18768} {RNA1310_32519} {RNA815_6130}
17. MligTC455_39550 1363 28.4 Mlig455_064780

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.374

Region-enriched R5: 1.797/0.04927

2.638 - - - 0.962 0.837 0.839 Mlig455_064780 {REF} {Length: 2221} {Pfam: Universal stress protein family [PF00582.28, score=100.0]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=106, Expect=7e-30]} {RNA1509_6489} {RNA1310_12949} {RNA815_11224}
18. MligTC455_29708 75761 1578.36 Mlig455_040690, Mlig455_064560

Neo: -

Age: -

Region-enriched R3: 1.504/0.04283

ACTG1 2.616 - 0.819 0.840 0.957 - -

Mlig455_040690 {REF} {Length: 1968} {Pfam: Actin [PF00022.21, score=495.2]} {Human: ENSG00000184009, ACTG1, actin gamma 1, [RH, Score=754, Expect=0.0]; ENSG00000075624, ACTB, actin beta, [RH, Score=753, Expect=0.0]; ENSG00000163017, ACTG2, actin, gamma 2, smooth muscle, enteric, [RH, Score=734, Expect=0.0]; ENSG00000143632, ACTA1, actin, alpha 1, skeletal muscle, [RH, Score=733, Expect=0.0]; ENSG00000107796, ACTA2, actin, alpha 2, smooth muscle, aorta, [RH, Score=733, Expect=0.0]; ENSG00000159251, ACTC1, actin, alpha, cardiac muscle 1, [RH, Score=731, Expect=0.0]; ENSG00000169067, ACTBL2, actin, beta like 2, [RH, Score=717, Expect=0.0]} {Mouse: ENSMUSG00000062825, Actg1, actin, gamma, cytoplasmic 1, [RH, Score=754, Expect=0.0]; ENSMUSG00000029580, Actb, actin, beta, [RH, Score=753, Expect=0.0]; ENSMUSG00000059430, Actg2, actin, gamma 2, smooth muscle, enteric, [RH, Score=734, Expect=0.0]; ENSMUSG00000035783, Acta2, actin, alpha 2, smooth muscle, aorta, [RH, Score=733, Expect=0.0]; ENSMUSG00000031972, Acta1, actin, alpha 1, skeletal muscle, [RH, Score=733, Expect=0.0]; ENSMUSG00000068614, Actc1, actin, alpha, cardiac muscle 1, [RH, Score=731, Expect=0.0]; ENSMUSG00000055194, Actbl2, actin, beta-like 2, [RH, Score=726, Expect=0.0]} {Dmel: FBgn0000042, Act5C, Actin 5C, [RH, Score=756, Expect=0.0]} {Celegans: WBGene00000066, act-4, Actin-4, [RH, Score=757, Expect=0.0]} {Smed: dd_Smed_v6_3_0_1, dd_Smed_v6_3_0_1, [RH, Score=753, Expect=0.0]} {RNA1509_424, RNA1509_47715} {RNA1310_16469.2, RNA1509_47715} {RNA1509_47715, RNA815_4929.3}

Mlig455_064560 {REF} {Length: 1687} {Pfam: Actin [PF00022.21, score=495.2]} {Human: ENSG00000184009, ACTG1, actin gamma 1, [RH, Score=754, Expect=0.0]; ENSG00000075624, ACTB, actin beta, [RH, Score=753, Expect=0.0]; ENSG00000163017, ACTG2, actin, gamma 2, smooth muscle, enteric, [RH, Score=734, Expect=0.0]; ENSG00000143632, ACTA1, actin, alpha 1, skeletal muscle, [RH, Score=733, Expect=0.0]; ENSG00000107796, ACTA2, actin, alpha 2, smooth muscle, aorta, [RH, Score=733, Expect=0.0]; ENSG00000159251, ACTC1, actin, alpha, cardiac muscle 1, [RH, Score=731, Expect=0.0]; ENSG00000169067, ACTBL2, actin, beta like 2, [RH, Score=717, Expect=0.0]} {Mouse: ENSMUSG00000062825, Actg1, actin, gamma, cytoplasmic 1, [RH, Score=754, Expect=0.0]; ENSMUSG00000029580, Actb, actin, beta, [RH, Score=753, Expect=0.0]; ENSMUSG00000059430, Actg2, actin, gamma 2, smooth muscle, enteric, [RH, Score=734, Expect=0.0]; ENSMUSG00000035783, Acta2, actin, alpha 2, smooth muscle, aorta, [RH, Score=733, Expect=0.0]; ENSMUSG00000031972, Acta1, actin, alpha 1, skeletal muscle, [RH, Score=733, Expect=0.0]; ENSMUSG00000068614, Actc1, actin, alpha, cardiac muscle 1, [RH, Score=731, Expect=0.0]; ENSMUSG00000055194, Actbl2, actin, beta-like 2, [RH, Score=726, Expect=0.0]} {Dmel: FBgn0000042, Act5C, Actin 5C, [RH, Score=756, Expect=0.0]} {Celegans: WBGene00000066, act-4, Actin-4, [RH, Score=757, Expect=0.0]} {Smed: dd_Smed_v6_3_0_1, dd_Smed_v6_3_0_1, [RH, Score=753, Expect=0.0]} {RNA1509_23256, RNA1509_25656, RNA1509_32867, RNA1509_424, RNA1509_479, RNA1509_54537} {RNA1310_16469.2, RNA1509_23256, RNA1509_25656, RNA1509_32867, RNA1509_479, RNA1509_54537} {RNA1509_23256, RNA1509_25656, RNA1509_32867, RNA1509_479, RNA1509_54537, RNA815_4929.3}
19. MligTC455_45742 2132 44.42 Mlig455_003184, Mlig455_003387

Neo: -

Age: logFC(26M/2M)=0.345

Region-specific R4: 3.405
Region-specific R3: 3.388

Region-enriched R4: 3.484/0.00000
Region-enriched R3: 2.393/0.00000
Region-enriched R5: 1.235/0.00412

SLC22A4, SLC22A5 2.587 - 0.778 - - 0.848 0.961

Mlig455_003184 {REF} {Length: 2170} {Pfam: Sugar (and other) transporter [PF00083.26, score=102.2]; Major Facilitator Superfamily [PF07690.18, score=60.9]} {Human: ENSG00000197208, SLC22A4, solute carrier family 22 member 4, [Score=274, Expect=4e-84]; ENSG00000197375, SLC22A5, solute carrier family 22 member 5, [Score=274, Expect=7e-84]} {Mouse: ENSMUSG00000063652, Slc22a21, solute carrier family 22 (organic cation transporter), member 21, [Score=278, Expect=1e-85]} {Dmel: FBgn0019952, Orct, Organic cation transporter, [Score=285, Expect=2e-88]} {Celegans: WBGene00003842, oct-1, Organic cation transporter 1, [Score=240, Expect=4e-71]} {Smed: dd_Smed_v6_10826_0_2, dd_Smed_v6_10826_0_2, [Score=198, Expect=7e-56]} {RNA1509_40645} {RNA1310_12725.1} {RNA815_4270}

Mlig455_003387 {REF} {Length: 2455} {Pfam: Sugar (and other) transporter [PF00083.26, score=70.5]; Major Facilitator Superfamily [PF07690.18, score=57.3]} {Human: ENSG00000197375, SLC22A5, solute carrier family 22 member 5, [Score=154, Expect=6e-42]; ENSG00000197208, SLC22A4, solute carrier family 22 member 4, [Score=147, Expect=2e-39]} {Mouse: ENSMUSG00000063652, Slc22a21, solute carrier family 22 (organic cation transporter), member 21, [Score=154, Expect=6e-42]} {Dmel: FBgn0019952, Orct, Organic cation transporter, [Score=174, Expect=1e-49]} {Celegans: WBGene00003843, oct-2, Organic Cation Transporter; Organic cation transporter, [Score=113, Expect=2e-27]} {Smed: dd_Smed_v6_10826_0_2, dd_Smed_v6_10826_0_2, [Score=116, Expect=1e-28]} {RNA1509_11765, RNA1509_40645} {RNA1310_12725.1, RNA1509_11765} {RNA1509_11765, RNA815_4270}
20. MligTC455_15733 28121 585.86 Mlig455_067264

Neo: -

Age: logFC(26M/2M)=-0.415

2.576 - - 0.729 0.954 - 0.893 Mlig455_067264 {REF} {Length: 1482} {Pfam: Protein of unknown function (DUF3421) [PF11901.10, score=119.0]} {Dmel: FBgn0034583, CG10527, [Score=73.9, Expect=5e-16]} {Smed: dd_Smed_v6_766_0_1, dd_Smed_v6_766_0_1, [RH, Score=136, Expect=1e-41]} {RNA1509_18673, RNA1509_9503} {RNA1310_39489, RNA1509_9503} {RNA1509_9503, RNA815_16771}
21. MligTC455_43368 6858 142.86 Mlig455_048986, Mlig455_049002

Neo: -

Age: Up-Down-Down

ACHE 2.532 - 0.740 - 0.836 - 0.956

Mlig455_048986 {REF} {Length: 14781} {Pfam: Carboxylesterase family [PF00135.30, score=2484.2]; alpha/beta hydrolase fold [PF07859.15, score=129.3]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=238, Expect=8e-66]} {Mouse: ENSMUSG00000058019, Ces5a, carboxylesterase 5A, [RH, Score=209, Expect=1e-56]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=189, Expect=3e-49]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=213, Expect=1e-57]} {Smed: dd_Smed_v6_10334_0_1, dd_Smed_v6_10334_0_1, [Score=202, Expect=8e-54]} {RNA1509_1156, RNA1509_14744, RNA1509_15426, RNA1509_18645, RNA1509_25748, RNA1509_38830, RNA1509_6237, RNA1509_82, RNA1509_8879} {RNA1310_83.1, RNA1509_1156, RNA1509_14744, RNA1509_15426, RNA1509_18645, RNA1509_25748, RNA1509_38830, RNA1509_6237, RNA1509_8879} {RNA1509_1156, RNA1509_14744, RNA1509_15426, RNA1509_18645, RNA1509_25748, RNA1509_38830, RNA1509_6237, RNA1509_8879, RNA815_40.1}

Mlig455_049002 {REF} {Length: 15214} {Pfam: Carboxylesterase family [PF00135.30, score=2695.8]; alpha/beta hydrolase fold [PF07859.15, score=131.9]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=238, Expect=1e-65]} {Mouse: ENSMUSG00000058019, Ces5a, carboxylesterase 5A, [RH, Score=211, Expect=7e-57]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=191, Expect=5e-50]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=207, Expect=1e-55]} {Smed: dd_Smed_v6_10334_0_1, dd_Smed_v6_10334_0_1, [Score=199, Expect=5e-53]} {RNA1509_82, RNA1509_8738} {RNA1310_83.1, RNA1509_8738} {RNA1509_8738, RNA815_40.1}
22. MligTC455_50237 17180 357.92 Mlig455_043841

Neo: -

Age: -

Region-enriched R3: 1.269/0.03286
Region-enriched R5: 1.202/0.01765

TSPAN7 2.507 - 0.823 - 0.952 0.732 - Mlig455_043841 {REF} {Length: 1652} {Pfam: Tetraspanin family [PF00335.22, score=140.6]} {Human: ENSG00000156298, TSPAN7, tetraspanin 7, [RH, Score=80.9, Expect=8e-17]} {Mouse: ENSMUSG00000058254, Tspan7, tetraspanin 7, [RH, Score=83.2, Expect=9e-18]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [Score=96.3, Expect=2e-22]} {Celegans: WBGene00006633, tsp-7, Tetraspanin, [Score=67.0, Expect=1e-12]} {Smed: dd_Smed_v6_354_0_1, dd_Smed_v6_354_0_1, [RH, Score=153, Expect=1e-43]} {RNA1509_333, RNA1509_34119} {RNA1310_21956, RNA1509_333, RNA1509_34119} {RNA1509_333, RNA1509_34119, RNA815_7133.1}
23. MligTC455_21272 4347 90.56 Mlig455_003588

Neo: -

Age: -

Region-enriched R3: 1.729/0.00219
Region-enriched R5: 1.335/0.01435

SLC5A8 2.479 - 0.784 - 0.705 - 0.990 Mlig455_003588 {REF} {Length: 5902} {Pfam: Sodium:solute symporter family [PF00474.19, score=128.2]} {Human: ENSG00000262217, SLC5A8, solute carrier family 5 member 8, [Score=373, Expect=2e-120]; ENSG00000256870, SLC5A8, solute carrier family 5 member 8, [Score=373, Expect=2e-120]; ENSG00000138074, SLC5A6, solute carrier family 5 member 6, [Score=367, Expect=2e-117]; ENSG00000148942, SLC5A12, solute carrier family 5 member 12, [Score=358, Expect=1e-114]} {Mouse: ENSMUSG00000020062, Slc5a8, solute carrier family 5 (iodide transporter), member 8, [Score=377, Expect=6e-122]; ENSMUSG00000041644, Slc5a12, solute carrier family 5 (sodium/glucose cotransporter), member 12, [Score=363, Expect=2e-116]} {Dmel: FBgn0034494, CG10444, [Score=330, Expect=2e-104]} {Celegans: WBGene00014092, ZK822.5, [Score=226, Expect=2e-65]} {Smed: dd_Smed_v6_14173_0_1, dd_Smed_v6_14173_0_1, [Score=345, Expect=2e-110]} {RNA1509_1120} {RNA1310_5768} {RNA815_1831}
24. MligTC455_45293 1305 27.18 Mlig455_051600

Neo: -

Age: -

SUSD2 1.777 - - - - 0.963 0.814 Mlig455_051600 {REF} {Length: 5138} {Pfam: von Willebrand factor type D domain [PF00094.27, score=37.0]} {Human: ENSG00000099994, SUSD2, sushi domain containing 2, [Score=82.8, Expect=6e-16]} {Mouse: ENSMUSG00000006342, Susd2, sushi domain containing 2, [Score=100, Expect=7e-22]} {Dmel: FBgn0051004, mesh, [Score=102, Expect=3e-22]} {RNA1509_1220, RNA1509_1883, RNA1509_34687, RNA1509_36798, RNA1509_40605} {RNA1310_2718.1, RNA1509_1883, RNA1509_34687, RNA1509_36798, RNA1509_40605} {RNA1509_1883, RNA1509_34687, RNA1509_36798, RNA1509_40605, RNA815_500}
25. MligTC455_14370 943 19.64 Mlig455_063547

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-2.337

Region-enriched R4: 2.732/0.00256
Region-enriched R5: 2.309/0.00365
Region-enriched R3: 2.214/0.02131

CYP2C8 1.736 - - - - 0.778 0.958 Mlig455_063547 {REF} {Length: 1886} {Pfam: Cytochrome P450 [PF00067.24, score=279.9]} {Human: ENSG00000138115, CYP2C8, cytochrome P450 family 2 subfamily C member 8, [Score=262, Expect=2e-81]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [Score=256, Expect=6e-79]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [Score=249, Expect=3e-76]} {Mouse: ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [Score=259, Expect=2e-80]; ENSMUSG00000003053, Cyp2c29, cytochrome P450, family 2, subfamily c, polypeptide 29, [Score=258, Expect=4e-80]; ENSMUSG00000032808, Cyp2c38, cytochrome P450, family 2, subfamily c, polypeptide 38, [Score=258, Expect=6e-80]; ENSMUSG00000042248, Cyp2c37, cytochrome P450, family 2. subfamily c, polypeptide 37, [Score=255, Expect=7e-79]; ENSMUSG00000040660, Cyp2b9, cytochrome P450, family 2, subfamily b, polypeptide 9, [Score=253, Expect=4e-78]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [Score=252, Expect=2e-77]; ENSMUSG00000030483, Cyp2b10, cytochrome P450, family 2, subfamily b, polypeptide 10, [Score=252, Expect=2e-77]; ENSMUSG00000074254, Cyp2a4, cytochrome P450, family 2, subfamily a, polypeptide 4, [Score=252, Expect=1e-77]; ENSMUSG00000025003, Cyp2c39, cytochrome P450, family 2, subfamily c, polypeptide 39, [Score=251, Expect=3e-77]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=251, Expect=3e-77]; ENSMUSG00000054827, Cyp2c50, cytochrome P450, family 2, subfamily c, polypeptide 50, [Score=249, Expect=1e-76]; ENSMUSG00000005547, Cyp2a5, cytochrome P450, family 2, subfamily a, polypeptide 5, [Score=249, Expect=2e-76]; ENSMUSG00000049685, Cyp2g1, cytochrome P450, family 2, subfamily g, polypeptide 1, [Score=248, Expect=7e-76]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [Score=248, Expect=6e-76]; ENSMUSG00000040650, Cyp2b23, cytochrome P450, family 2, subfamily b, polypeptide 23, [Score=248, Expect=5e-76]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [Score=247, Expect=1e-75]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=202, Expect=2e-58]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [Score=215, Expect=1e-63]} {Smed: dd_Smed_v6_2351_0_2, dd_Smed_v6_2351_0_2, [Score=263, Expect=6e-82]} {RNA1509_20560} {RNA1310_19381, RNA1509_20560} {RNA1509_20560, RNA815_15513}
26. MligTC455_16017 1654 34.46 Mlig455_052747

Neo: -

Age: -

Region-enriched R4: 1.664/0.00032
Region-enriched R3: 1.084/0.03324

PM20D2 1.707 - - - 0.751 - 0.956 Mlig455_052747 {REF} {Length: 1787} {TRANSSPLICED} {Pfam: Peptidase dimerisation domain [PF07687.16, score=33.3]; Peptidase family M20/M25/M40 [PF01546.30, score=29.9]} {Human: ENSG00000146281, PM20D2, peptidase M20 domain containing 2, [RH, Score=356, Expect=5e-120]} {Mouse: ENSMUSG00000054659, Pm20d2, peptidase M20 domain containing 2, [RH, Score=355, Expect=1e-119]} {Smed: dd_Smed_v6_7395_0_1, dd_Smed_v6_7395_0_1, [RH, Score=337, Expect=9e-114]} {RNA1509_27696, RNA1509_38773, RNA1509_53331} {RNA1310_17432.1, RNA1509_27696, RNA1509_38773, RNA1509_53331} {RNA1509_27696, RNA1509_38773, RNA1509_53331, RNA815_6952}
27. MligTC455_53423 1277 26.61 Mlig455_016245

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.359

Region-enriched R4: 2.028/0.03482

0.987 - - - 0.987 - - Mlig455_016245 {REF} {Length: 1291} {RNA1509_20275} {RNA1310_27132, RNA1509_20275} {RNA1509_20275, RNA815_13259}
28. MligTC455_36407 33888 706 Mlig455_022240

Neo: -

Age: Up-Down-Down

0.964 - - - - - 0.964 Mlig455_022240 {REF} {Length: 7056} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=127.4]; von Willebrand factor type D domain [PF00094.27, score=53.4]; Domain of unknown function (DUF1943) [PF09172.13, score=51.2]} {Celegans: WBGene00006930, vit-6, Vitellogenin-6, [Score=70.9, Expect=1e-11]} {RNA1509_20342, RNA1509_27203, RNA1509_351, RNA1509_6, RNA1509_7840} {RNA1310_450.1, RNA1509_20342, RNA1509_27203, RNA1509_351, RNA1509_7840} {RNA1509_20342, RNA1509_27203, RNA1509_351, RNA1509_7840, RNA815_123.1}
29. MligTC455_36408 33981 707.94 Mlig455_022255

Neo: -

Age: Up-Down-Down

0.962 - - - - - 0.962 Mlig455_022255 {REF} {Length: 6854} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=124.9]; von Willebrand factor type D domain [PF00094.27, score=53.5]; Domain of unknown function (DUF1943) [PF09172.13, score=51.2]} {Celegans: WBGene00006930, vit-6, Vitellogenin-6, [RH, Score=76.3, Expect=2e-13]} {RNA1509_1285} {RNA1310_4285.1} {RNA815_123.1}
30. MligTC455_43587 981 20.44 Mlig455_064849

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.445

Region-enriched R4: 1.141/0.04839

0.956 - - - - 0.956 - Mlig455_064849 {REF} {Length: 1597} {RNA1509_13829} {RNA1310_22619, RNA1509_13829} {RNA1509_13829, RNA815_12635}
31. MligTC455_35362 1327 27.64 Mlig455_008538

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.718

Region-enriched R4: 1.957/0.01784
Region-enriched R5: 1.459/0.03051

HDHD5 0.955 - - - 0.955 - - Mlig455_008538 {REF} {Length: 1726} {Pfam: Haloacid dehalogenase-like hydrolase [PF13344.8, score=49.6]; HAD-hyrolase-like [PF13242.8, score=33.9]} {Human: ENSG00000069998, HDHD5, haloacid dehalogenase like hydrolase domain containing 5, [Score=285, Expect=8e-92]} {Mouse: ENSMUSG00000058979, Hdhd5, haloacid dehalogenase like hydrolase domain containing 5, [Score=271, Expect=1e-86]} {Celegans: WBGene00019255, H32C10.1, [RH, Score=206, Expect=6e-62]} {Smed: dd_Smed_v6_1170_0_1, dd_Smed_v6_1170_0_1, [RH, Score=430, Expect=3e-149]} {RNA1509_17924, RNA1509_51751} {RNA1310_18496, RNA1509_17924, RNA1509_51751} {RNA1509_17924, RNA1509_51751, RNA815_7610}

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