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Results for MligTC455_27625

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_27625 5733 119.44 Mlig455_018765

Neo: -

Age: Down-Down-Up

Region-enriched R3: 1.886/0.00051

 MATN2 Mlig455_018765 {REF} {Length: 2544} {Pfam: von Willebrand factor type A domain [PF00092.30, score=235.9]; von Willebrand factor type A domain [PF13519.8, score=103.0]; von Willebrand factor type A domain [PF13768.8, score=54.3]; VWA domain containing CoxE-like protein [PF05762.16, score=36.8]; Protein of unknown function (DUF1194) [PF06707.13, score=35.1]} {Human: ENSG00000132561, MATN2, matrilin 2, [Score=97.1, Expect=3e-20]} {Mouse: ENSMUSG00000040533, Matn1, matrilin 1, cartilage matrix protein, [Score=105, Expect=1e-23]} {Celegans: WBGene00003482, mua-3, Transmembrane cell adhesion receptor mua-3, [Score=82.0, Expect=8e-16]} {Smed: dd_Smed_v6_2674_0_1, dd_Smed_v6_2674_0_1, [Score=92.0, Expect=3e-19]} {RNA1509_3165} {RNA1310_8996, RNA1509_3165} {RNA1509_3165, RNA815_2915.1}

Cumulative graph for MligTC455_27625

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.155 6.995 0.81828 1.00000
RegionR2 -0.786 6.995 0.16011 0.50068
RegionR3 1.886 6.995 0.00001 0.00051
RegionR4 0.66 6.995 0.19606 0.47436
RegionR5 0.498 6.995 0.26515 0.58807
RegionR6 0.676 6.995 0.14194 0.67517
RegionR7 -2.34 6.995 0.00015 0.00809
RegionR8 -0.749 6.995 0.20811 0.80912

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.443 6.995 0.59878 1.00000
RegenerationR2 -0.325 6.995 0.60069 0.91575
RegenerationR3 -0.453 6.995 0.44810 0.83109
RegenerationR4 0.41 6.995 0.50895 0.87397
RegenerationR5 0.238 6.995 0.69284 0.94895
RegenerationR6 0.423 6.995 0.48592 0.79582
RegenerationBL 0.271 6.995 0.62640 0.96866
RegenerationTP 0.188 6.995 0.76150 1.00000


Genes with expression patterns similar to MligTC455_27625

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_27625 5733 119.44 Mlig455_018765

Neo: -

Age: Down-Down-Up

Region-enriched R3: 1.886/0.00051

 MATN2 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_018765 {REF} {Length: 2544} {Pfam: von Willebrand factor type A domain [PF00092.30, score=235.9]; von Willebrand factor type A domain [PF13519.8, score=103.0]; von Willebrand factor type A domain [PF13768.8, score=54.3]; VWA domain containing CoxE-like protein [PF05762.16, score=36.8]; Protein of unknown function (DUF1194) [PF06707.13, score=35.1]} {Human: ENSG00000132561, MATN2, matrilin 2, [Score=97.1, Expect=3e-20]} {Mouse: ENSMUSG00000040533, Matn1, matrilin 1, cartilage matrix protein, [Score=105, Expect=1e-23]} {Celegans: WBGene00003482, mua-3, Transmembrane cell adhesion receptor mua-3, [Score=82.0, Expect=8e-16]} {Smed: dd_Smed_v6_2674_0_1, dd_Smed_v6_2674_0_1, [Score=92.0, Expect=3e-19]} {RNA1509_3165} {RNA1310_8996, RNA1509_3165} {RNA1509_3165, RNA815_2915.1}
2. MligTC455_27626 5517 114.94 Mlig455_018931

Neo: -

Age: Down-Down-Up

Region-enriched R3: 1.591/0.03259

 MATN2 5.514 0.913 0.970 0.759 0.919 0.975 0.978 Mlig455_018931 {REF} {Length: 2583} {Pfam: von Willebrand factor type A domain [PF00092.30, score=235.9]; von Willebrand factor type A domain [PF13519.8, score=103.0]; von Willebrand factor type A domain [PF13768.8, score=54.3]; VWA domain containing CoxE-like protein [PF05762.16, score=36.8]; Protein of unknown function (DUF1194) [PF06707.13, score=35.1]} {Human: ENSG00000132561, MATN2, matrilin 2, [Score=96.7, Expect=3e-20]} {Mouse: ENSMUSG00000040533, Matn1, matrilin 1, cartilage matrix protein, [Score=105, Expect=1e-23]} {Celegans: WBGene00003482, mua-3, Transmembrane cell adhesion receptor mua-3, [Score=82.0, Expect=8e-16]} {Smed: dd_Smed_v6_2674_0_1, dd_Smed_v6_2674_0_1, [Score=92.0, Expect=3e-19]} {RNA1509_21765, RNA1509_317, RNA1509_9118} {RNA1310_8996, RNA1509_21765, RNA1509_317, RNA1509_9118} {RNA1509_21765, RNA1509_317, RNA1509_9118, RNA815_2915.1}
3. MligTC455_43133 2633 54.86 Mlig455_033697, Mlig455_050134

Neo: -

Age: -

Region-enriched R3: 2.075/0.00231
Region-enriched R4: 1.915/0.02367

 ENPP5 5.437 0.889 0.885 0.845 0.923 0.927 0.968

Mlig455_033697 {REF} {Length: 1895} {Pfam: Type I phosphodiesterase / nucleotide pyrophosphatase [PF01663.24, score=202.8]; Sulfatase [PF00884.25, score=38.8]; Protein of unknown function (DUF1501) [PF07394.14, score=23.7]; Metalloenzyme superfamily [PF01676.20, score=18.8]} {Human: ENSG00000112796, ENPP5, ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative), [Score=207, Expect=8e-60]; ENSG00000001561, ENPP4, ectonucleotide pyrophosphatase/phosphodiesterase 4, [Score=198, Expect=1e-56]} {Mouse: ENSMUSG00000023960, Enpp5, ectonucleotide pyrophosphatase/phosphodiesterase 5, [Score=209, Expect=1e-60]} {Celegans: WBGene00015283, C01B10.9, [RH, Score=160, Expect=1e-42]} {Smed: dd_Smed_v6_9016_0_1, dd_Smed_v6_9016_0_1, [Score=180, Expect=5e-50]} {RNA1509_8220} {RNA1310_19894.1} {RNA815_8419}

Mlig455_050134 {REF} {Length: 1895} {Pfam: Type I phosphodiesterase / nucleotide pyrophosphatase [PF01663.24, score=201.5]; Sulfatase [PF00884.25, score=38.5]; Protein of unknown function (DUF1501) [PF07394.14, score=21.0]; Metalloenzyme superfamily [PF01676.20, score=18.3]} {Human: ENSG00000112796, ENPP5, ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative), [Score=206, Expect=2e-59]; ENSG00000001561, ENPP4, ectonucleotide pyrophosphatase/phosphodiesterase 4, [Score=197, Expect=2e-56]} {Mouse: ENSMUSG00000023960, Enpp5, ectonucleotide pyrophosphatase/phosphodiesterase 5, [Score=208, Expect=2e-60]} {Celegans: WBGene00015283, C01B10.9, [RH, Score=160, Expect=2e-42]} {Smed: dd_Smed_v6_9016_0_1, dd_Smed_v6_9016_0_1, [Score=179, Expect=1e-49]} {RNA1509_8220} {RNA1310_19894.1} {RNA815_8419}
4. MligTC455_52971 2407 50.15 Mlig455_050623

Neo: -

Age: logFC(26M/2M)=-0.616

Region-enriched R4: 1.402/0.00014
Region-enriched R3: 1.372/0.00001

 5.262 0.764 0.852 0.866 0.896 0.960 0.924 Mlig455_050623 {REF} {Length: 1302} {RNA1509_18850, RNA1509_3980, RNA1509_4657} {RNA1310_29014, RNA1509_18850, RNA1509_3980, RNA1509_4657} {RNA1509_18850, RNA1509_3980, RNA1509_4657, RNA815_8071.2}
5. MligTC455_39170 3221 67.1 Mlig455_038903

Neo: -

Age: logFC(26M/2M)=0.340

Region-enriched R3: 2.495/0.00000
Region-enriched R4: 1.609/0.00501
Region-enriched R5: 1.221/0.00810

 ALDH2 5.235 0.764 0.960 0.735 0.968 0.898 0.910 Mlig455_038903 {REF} {Length: 2307} {Pfam: Aldehyde dehydrogenase family [PF00171.24, score=593.4]} {Human: ENSG00000111275, ALDH2, aldehyde dehydrogenase 2 family member, [RH, Score=780, Expect=0.0]; ENSG00000137124, ALDH1B1, aldehyde dehydrogenase 1 family member B1, [RH, Score=753, Expect=0.0]} {Mouse: ENSMUSG00000029455, Aldh2, aldehyde dehydrogenase 2, mitochondrial, [RH, Score=768, Expect=0.0]; ENSMUSG00000035561, Aldh1b1, aldehyde dehydrogenase 1 family, member B1, [RH, Score=749, Expect=0.0]} {Dmel: FBgn0012036, Aldh, Aldehyde dehydrogenase, [RH, Score=718, Expect=0.0]} {Celegans: WBGene00000107, alh-1, ALdehyde deHydrogenase, [RH, Score=725, Expect=0.0]} {Smed: dd_Smed_v6_1339_0_1, dd_Smed_v6_1339_0_1, [RH, Score=725, Expect=0.0]} {RNA1509_1186} {RNA1310_3799.1} {RNA815_1286.1}
6. MligTC455_53877 1399 29.15 Mlig455_016664

Neo: -

Age: logFC(26M/2M)=0.488

Region-enriched R3: 1.947/0.00083
Region-enriched R4: 1.666/0.01644

 CLCA1 5.09 0.775 0.751 0.795 0.960 0.903 0.906 Mlig455_016664 {REF} {Length: 4164} {Pfam: Calcium-activated chloride channel N terminal [PF08434.13, score=169.0]} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [Score=166, Expect=4e-43]} {Mouse: ENSMUSG00000028255, Clca1, chloride channel accessory 1, [Score=163, Expect=2e-42]} {RNA1509_1021} {RNA1310_5461.1} {RNA815_1665}
7. MligTC455_33836 2065 43.02 Mlig455_036757

Neo: -

Age: logFC(26M/2M)=-0.242

Region-enriched R3: 1.925/0.00000
Region-enriched R4: 1.200/0.01490
Region-enriched R5: 1.020/0.01114

 CYP2J2 5.089 0.764 0.877 0.784 0.951 0.867 0.846 Mlig455_036757 {REF} {Length: 1902} {Pfam: Cytochrome P450 [PF00067.24, score=314.8]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=252, Expect=2e-77]} {Mouse: ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=248, Expect=4e-76]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [Score=248, Expect=4e-76]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [Score=246, Expect=3e-75]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [Score=246, Expect=2e-75]; ENSMUSG00000066097, Cyp2j11, cytochrome P450, family 2, subfamily j, polypeptide 11, [Score=240, Expect=7e-73]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [Score=239, Expect=1e-72]; ENSMUSG00000082932, Cyp2j8, cytochrome P450, family 2, subfamily j, polypeptide 8, [Score=236, Expect=2e-71]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=208, Expect=1e-60]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [Score=226, Expect=7e-68]} {Smed: dd_Smed_v6_5344_0_2, dd_Smed_v6_5344_0_2, [RH, Score=260, Expect=8e-81]} {RNA1509_32471} {RNA1310_10330} {RNA815_3898.1}
8. MligTC455_48233 2702 56.29 Mlig455_015578

Neo: -

Age: logFC(26M/2M)=1.240

Region-enriched R4: 2.285/0.00042
Region-enriched R3: 2.171/0.00046
Region-enriched R5: 1.576/0.01004

 GSTP1 5.022 0.747 0.839 0.812 0.961 0.825 0.838 Mlig455_015578 {REF} {Length: 1377} {Pfam: Glutathione S-transferase, C-terminal domain [PF14497.8, score=56.6]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=40.4]; Glutathione S-transferase, N-terminal domain [PF02798.22, score=28.9]; Glutathione S-transferase, N-terminal domain [PF13417.8, score=26.9]; Glutathione S-transferase, N-terminal domain [PF13409.8, score=22.2]; Glutathione S-transferase, C-terminal domain [PF13410.8, score=20.0]} {Human: ENSG00000084207, GSTP1, glutathione S-transferase pi 1, [Score=117, Expect=2e-32]} {Mouse: ENSMUSG00000097830, Gstp1, glutathione S-transferase, pi 1, [Score=125, Expect=2e-35]; ENSMUSG00000060803, Gstp1, glutathione S-transferase, pi 1, [Score=125, Expect=2e-35]; ENSMUSG00000097808, Gstp2, glutathione S-transferase, pi 2, [Score=123, Expect=1e-34]; ENSMUSG00000038155, Gstp2, glutathione S-transferase, pi 2, [Score=123, Expect=1e-34]} {Dmel: FBgn0010226, GstS1, Glutathione S transferase S1, [Score=85.1, Expect=6e-20]} {Celegans: WBGene00001771, gst-23, Glutathione S-Transferase, [Score=114, Expect=9e-32]} {Smed: dd_Smed_v6_1206_0_1, dd_Smed_v6_1206_0_1, [Score=82.8, Expect=1e-19]} {RNA1509_18142, RNA1509_2555, RNA1509_25858, RNA1509_4577} {RNA1310_22609, RNA1509_18142, RNA1509_2555, RNA1509_25858, RNA1509_4577} {RNA1509_18142, RNA1509_2555, RNA1509_25858, RNA1509_4577, RNA815_19011}
9. MligTC455_43756 3225 67.19 Mlig455_010402

Neo: -

Age: -

Region-enriched R3: 1.722/0.00762

 4.971 0.866 0.778 0.767 0.707 0.888 0.965 Mlig455_010402 {REF} {Length: 2001} {Pfam: Innexin [PF00876.20, score=339.7]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=100, Expect=3e-23]} {Celegans: WBGene00006749, unc-9, Innexin unc-9, [Score=291, Expect=2e-95]} {Smed: dd_Smed_v6_734_0_2, dd_Smed_v6_734_0_2, [Score=292, Expect=3e-95]} {RNA1509_21594, RNA1509_22136, RNA1509_30214, RNA1509_32964, RNA1509_3943, RNA1509_49855} {RNA1310_16777, RNA1509_21594, RNA1509_22136, RNA1509_30214, RNA1509_32964, RNA1509_3943, RNA1509_49855} {RNA1509_21594, RNA1509_22136, RNA1509_30214, RNA1509_32964, RNA1509_3943, RNA1509_49855, RNA815_7295}
10. MligTC455_27540 1669 34.76 Mlig455_050550

Neo: -

Age: logFC(26M/2M)=0.741

Region-enriched R3: 2.399/0.00000
Region-enriched R4: 1.902/0.00065
Region-enriched R5: 1.309/0.00668

 4.524 0.908 0.900 - 0.970 0.868 0.878 Mlig455_050550 {REF} {Length: 2834} {RNA1509_43749, RNA1509_45402} {RNA1310_6417, RNA1509_45402} {RNA1509_45402, RNA815_8474.1}
11. MligTC455_52436 4103 85.47 Mlig455_036594, Mlig455_057758

Neo: -

Age: -

Region-enriched R3: 2.299/0.00029

 FMO4 4.499 0.885 0.946 0.810 - 0.907 0.951

Mlig455_036594 {REF} {Length: 1772} {TRANSSPLICED} {Pfam: Flavin-binding monooxygenase-like [PF00743.21, score=121.5]; Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=43.8]; L-lysine 6-monooxygenase (NADPH-requiring) [PF13434.8, score=21.1]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=18.3]} {Human: ENSG00000076258, FMO4, flavin containing monooxygenase 4, [Score=104, Expect=1e-23]} {Mouse: ENSMUSG00000026560, Fmo9, flavin containing monooxygenase 9, [Score=102, Expect=5e-23]; ENSMUSG00000028088, Fmo5, flavin containing monooxygenase 5, [Score=102, Expect=3e-23]} {Dmel: FBgn0033079, Fmo-2, Flavin-containing monooxygenase 2, [Score=132, Expect=3e-34]} {Celegans: WBGene00016728, C46H11.2, Flavin-containing monooxygenase, [Score=108, Expect=1e-25]} {Smed: dd_Smed_v6_9449_0_1, dd_Smed_v6_9449_0_1, [Score=93.2, Expect=1e-20]} {RNA1509_13926} {RNA1310_13123.1} {RNA815_5157.1}

Mlig455_057758 {REF} {Length: 1759} {TRANSSPLICED} {Pfam: Flavin-binding monooxygenase-like [PF00743.21, score=125.0]; Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=49.5]; FAD-NAD(P)-binding [PF13454.8, score=29.2]; L-lysine 6-monooxygenase (NADPH-requiring) [PF13434.8, score=28.7]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=27.1]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=19.0]; FAD dependent oxidoreductase [PF01266.26, score=18.3]} {Human: ENSG00000076258, FMO4, flavin containing monooxygenase 4, [Score=111, Expect=1e-25]} {Mouse: ENSMUSG00000028088, Fmo5, flavin containing monooxygenase 5, [Score=113, Expect=2e-26]; ENSMUSG00000026560, Fmo9, flavin containing monooxygenase 9, [Score=108, Expect=6e-25]} {Dmel: FBgn0033079, Fmo-2, Flavin-containing monooxygenase 2, [Score=148, Expect=1e-39]} {Celegans: WBGene00016728, C46H11.2, Flavin-containing monooxygenase, [Score=108, Expect=9e-26]} {Smed: dd_Smed_v6_9449_0_1, dd_Smed_v6_9449_0_1, [Score=106, Expect=6e-25]} {RNA1509_13926} {RNA1310_13123.1} {RNA815_5157.1}
12. MligTC455_27541 1613 33.6 Mlig455_050579

Neo: -

Age: logFC(26M/2M)=0.592

Region-enriched R3: 2.383/0.00000
Region-enriched R4: 1.941/0.00031
Region-enriched R5: 1.306/0.00531

 ACHE 4.493 0.903 0.904 - 0.973 0.853 0.860 Mlig455_050579 {REF} {Length: 4445} {Pfam: Carboxylesterase family [PF00135.30, score=452.6]; alpha/beta hydrolase fold [PF07859.15, score=30.5]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=194, Expect=2e-51]; ENSG00000114200, BCHE, butyrylcholinesterase, [Score=192, Expect=3e-51]} {Mouse: ENSMUSG00000027792, Bche, butyrylcholinesterase, [Score=191, Expect=9e-51]; ENSMUSG00000023328, Ache, acetylcholinesterase, [Score=182, Expect=6e-48]} {Dmel: FBgn0032131, CG3841, [RH, Score=170, Expect=4e-44]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=164, Expect=4e-42]} {Smed: dd_Smed_v6_14790_0_1, dd_Smed_v6_14790_0_1, [Score=155, Expect=4e-39]} {RNA1509_43749} {RNA1310_6417, RNA1509_43749} {RNA1509_43749, RNA815_8474.1}
13. MligTC455_53878 8131 169.39 Mlig455_056351

Neo: -

Age: logFC(26M/2M)=0.398

Region-enriched R3: 1.950/0.00000
Region-enriched R5: 1.089/0.01986

 CLCA1 4.484 0.818 0.915 - 0.974 0.837 0.940 Mlig455_056351 {REF} {Length: 4429} {Pfam: Calcium-activated chloride channel N terminal [PF08434.13, score=166.8]; von Willebrand factor type A domain [PF00092.30, score=30.4]; von Willebrand factor type A domain [PF13519.8, score=27.0]; von Willebrand factor type A domain [PF13768.8, score=23.5]} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [Score=166, Expect=2e-41]} {Mouse: ENSMUSG00000028255, Clca1, chloride channel accessory 1, [Score=165, Expect=5e-41]} {Celegans: WBGene00018026, F35A5.4, [Score=58.2, Expect=3e-08]} {RNA1509_656} {RNA1310_5461.1} {RNA815_1665}
14. MligTC455_22592 6211 129.4 Mlig455_000657

Neo: -

Age: -

Region-enriched R4: 1.907/0.00463
Region-enriched R3: 1.880/0.00180
Region-enriched R5: 1.420/0.01682

 FTH1 4.47 0.851 0.872 - 0.921 0.876 0.950 Mlig455_000657 {REF} {Length: 1242} {Pfam: Ferritin-like domain [PF00210.26, score=95.7]} {Human: ENSG00000167996, FTH1, ferritin heavy chain 1, [Score=109, Expect=8e-30]} {Mouse: ENSMUSG00000024661, Fth1, ferritin heavy polypeptide 1, [Score=103, Expect=7e-28]; ENSMUSG00000024510, Ftmt, ferritin mitochondrial, [Score=101, Expect=3e-26]} {Dmel: FBgn0030449, Fer3HCH, Ferritin 3 heavy chain homologue, [Score=97.8, Expect=2e-25]} {Celegans: WBGene00001501, ftn-2, Ferritin, [Score=118, Expect=1e-33]} {Smed: dd_Smed_v6_3974_0_1, dd_Smed_v6_3974_0_1, [Score=124, Expect=3e-36]} {RNA1509_8084} {RNA1310_36954.1} {RNA815_13698.3}
15. MligTC455_28793 5084 105.92 Mlig455_060183

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.494

Region-enriched R3: 1.548/0.02653

 MUC5B 4.467 0.787 0.925 - 0.964 0.895 0.896 Mlig455_060183 {REF} {Length: 13150} {Pfam: Mucin-2 protein WxxW repeating region [PF13330.8, score=446.8]; von Willebrand factor type D domain [PF00094.27, score=233.8]; C8 domain [PF08742.13, score=102.9]; Trypsin Inhibitor like cysteine rich domain [PF01826.19, score=57.0]; F5/8 type C domain [PF00754.27, score=50.9]} {Human: ENSG00000117983, MUC5B, mucin 5B, oligomeric mucus/gel-forming, [RH, Score=593, Expect=7e-169]; ENSG00000215182, MUC5AC, mucin 5AC, oligomeric mucus/gel-forming, [RH, Score=590, Expect=7e-168]; ENSG00000283158, MUC5AC, mucin 5AC, oligomeric mucus/gel-forming, [RH, Score=590, Expect=7e-168]} {Mouse: ENSMUSG00000066108, Muc5b, mucin 5, subtype B, tracheobronchial, [RH, Score=545, Expect=1e-154]} {Dmel: FBgn0029167, Hml, Hemolectin, [RH, Score=512, Expect=6e-145]} {Celegans: WBGene00006820, unc-89, Muscle M-line assembly protein unc-89, [Score=68.6, Expect=2e-10]} {Smed: dd_Smed_v6_17988_0_1, dd_Smed_v6_17988_0_1, [Score=439, Expect=1e-123]} {RNA1509_4763} {RNA1310_151.1} {RNA815_89.1}
16. MligTC455_24083 6997 145.77 Mlig455_007319

Neo: -

Age: -

Region-enriched R3: 2.037/0.00010
Region-enriched R5: 1.165/0.04106

 ACHE 4.462 0.863 0.875 - 0.956 0.839 0.929 Mlig455_007319 {REF} {Length: 2399} {Pfam: Carboxylesterase family [PF00135.30, score=344.4]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=233, Expect=9e-68]} {Mouse: ENSMUSG00000023328, Ache, acetylcholinesterase, [Score=225, Expect=3e-65]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=183, Expect=6e-50]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=228, Expect=1e-66]} {Smed: dd_Smed_v6_4800_0_1, dd_Smed_v6_4800_0_1, [Score=184, Expect=4e-50]} {RNA1509_195, RNA1509_4270, RNA1509_51012} {RNA1310_9229, RNA1509_4270, RNA1509_51012} {RNA1509_4270, RNA1509_51012, RNA815_3141.1}
17. MligTC455_24086 11442 238.37 Mlig455_068330

Neo: -

Age: Up-Down-Up

Region-enriched R3: 2.329/0.00000
Region-enriched R6: 1.493/0.00384
Region-enriched R5: 1.266/0.00365

 ACHE 4.46 0.860 0.965 - 0.886 0.896 0.853 Mlig455_068330 {REF} {Length: 2275} {Pfam: Carboxylesterase family [PF00135.30, score=340.4]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=228, Expect=5e-66]} {Mouse: ENSMUSG00000023328, Ache, acetylcholinesterase, [Score=226, Expect=1e-65]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=191, Expect=1e-52]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=226, Expect=1e-65]} {Smed: dd_Smed_v6_14790_0_1, dd_Smed_v6_14790_0_1, [Score=202, Expect=4e-57]} {RNA1509_2293, RNA1509_46106} {RNA1310_10437.1, RNA1509_2293} {RNA1509_2293, RNA815_3976}
18. MligTC455_34844 2198 45.79 Mlig455_023760

Neo: -

Age: logFC(26M/2M)=0.545

Region-enriched R3: 1.526/0.03191

 CYP2J2 4.432 0.855 0.792 - 0.921 0.956 0.908 Mlig455_023760 {REF} {Length: 2332} {Pfam: Cytochrome P450 [PF00067.24, score=323.6]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=272, Expect=4e-85]} {Mouse: ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=275, Expect=2e-86]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=267, Expect=2e-83]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [RH, Score=263, Expect=2e-81]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=234, Expect=3e-70]} {Celegans: WBGene00018413, cyp-33C4, CYtochrome P450 family, [RH, Score=259, Expect=1e-80]} {Smed: dd_Smed_v6_2351_0_1, dd_Smed_v6_2351_0_1, [Score=265, Expect=6e-83]} {RNA1509_5390} {RNA1310_15059, RNA1509_5390} {RNA1509_5390, RNA815_5935.1}
19. MligTC455_32556 3264 68 Mlig455_063887

Neo: -

Age: logFC(26M/2M)=0.287

Region-enriched R3: 2.356/0.00263

 PRSS12 4.408 0.862 0.889 - 0.911 0.957 0.789 Mlig455_063887 {REF} {Length: 4839} {Pfam: Scavenger receptor cysteine-rich domain [PF00530.20, score=61.5]; Kringle domain [PF00051.20, score=54.5]; Low-density lipoprotein receptor domain class A [PF00057.20, score=44.2]; Lectin C-type domain [PF00059.23, score=26.4]; Scavenger receptor cysteine-rich domain [PF15494.8, score=21.1]} {Human: ENSG00000164099, PRSS12, serine protease 12, [Score=64.7, Expect=4e-10]; ENSG00000138131, LOXL4, lysyl oxidase like 4, [Score=63.2, Expect=2e-09]; ENSG00000115318, LOXL3, lysyl oxidase like 3, [Score=62.8, Expect=1e-10]} {Mouse: ENSMUSG00000027978, Prss12, protease, serine 12 neurotrypsin (motopsin), [Score=68.2, Expect=3e-11]; ENSMUSG00000021260, Hhipl1, hedgehog interacting protein-like 1, [Score=65.9, Expect=1e-10]} {Dmel: FBgn0023479, teq, Tequila, [Score=72.0, Expect=1e-12]} {Celegans: WBGene00003072, lrp-2, Low-density lipoprotein RecePtor related, [Score=63.2, Expect=8e-10]} {Smed: dd_Smed_v6_790_0_1, dd_Smed_v6_790_0_1, [Score=222, Expect=1e-60]} {RNA1509_337, RNA1509_44538, RNA1509_49914} {RNA1310_1502.1, RNA1509_337, RNA1509_44538, RNA1509_49914} {RNA1509_337, RNA1509_44538, RNA1509_49914, RNA815_422}
20. MligTC455_32555 3333 69.45 Mlig455_023825

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.526

Region-enriched R3: 1.882/0.00000
Region-enriched R4: 1.126/0.03622

 PRSS12 4.395 0.750 0.894 - 0.966 0.922 0.863 Mlig455_023825 {REF} {Length: 4714} {Pfam: Trypsin [PF00089.28, score=216.2]; Scavenger receptor cysteine-rich domain [PF00530.20, score=95.2]; Low-density lipoprotein receptor domain class A [PF00057.20, score=94.1]; Scavenger receptor cysteine-rich domain [PF15494.8, score=25.1]; Trypsin-like peptidase domain [PF13365.8, score=20.3]; Nematode trypsin-6-like family [PF03761.17, score=18.5]} {Human: ENSG00000164099, PRSS12, serine protease 12, [Score=220, Expect=4e-60]} {Mouse: ENSMUSG00000027978, Prss12, protease, serine 12 neurotrypsin (motopsin), [Score=212, Expect=3e-58]} {Dmel: FBgn0023479, teq, Tequila, [Score=286, Expect=1e-81]} {Celegans: WBGene00006620, svh-1, HGF/MSP/plasminogen-like protein, [RH, Score=191, Expect=2e-50]} {Smed: dd_Smed_v6_790_0_1, dd_Smed_v6_790_0_1, [Score=489, Expect=7e-158]} {RNA1509_337} {RNA1310_1502.2} {RNA815_422}
21. MligTC455_38724 5697 118.69 Mlig455_045051

Neo: -

Age: logFC(26M/2M)=-0.423

Region-enriched R3: 1.948/0.00202

 PANK4 4.356 0.734 0.817 - 0.947 0.950 0.908 Mlig455_045051 {REF} {Length: 2009} {Pfam: Fumble [PF03630.16, score=127.5]} {Human: ENSG00000157881, PANK4, pantothenate kinase 4, [Score=112, Expect=2e-26]; ENSG00000273494, PANK4, pantothenate kinase 4, [Score=112, Expect=2e-26]} {Mouse: ENSMUSG00000029056, Pank4, pantothenate kinase 4, [Score=102, Expect=2e-23]} {Dmel: FBgn0011205, fbl, fumble, [Score=86.7, Expect=1e-18]} {Celegans: WBGene00004068, pnk-1, PaNtothenate Kinase, [Score=82.4, Expect=3e-17]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [RH, Score=225, Expect=1e-70]} {RNA1509_11373, RNA1509_768} {RNA1310_14353, RNA1509_11373} {RNA1509_11373, RNA815_1414}
22. MligTC455_10015 1301 27.1 Mlig455_054875

Neo: -

Age: Up-Down-Up

Region-enriched R3: 2.120/0.00000
Region-enriched R4: 1.638/0.00586

 CYP2C8 4.348 0.795 0.854 - 0.964 0.862 0.873 Mlig455_054875 {REF} {Length: 2242} {Pfam: Cytochrome P450 [PF00067.24, score=314.1]} {Human: ENSG00000138115, CYP2C8, cytochrome P450 family 2 subfamily C member 8, [Score=241, Expect=3e-73]; ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [Score=236, Expect=8e-71]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [Score=233, Expect=2e-70]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [Score=233, Expect=2e-70]} {Mouse: ENSMUSG00000022445, Cyp2d26, cytochrome P450, family 2, subfamily d, polypeptide 26, [Score=241, Expect=2e-73]; ENSMUSG00000091867, Cyp2a22, cytochrome P450, family 2, subfamily a, polypeptide 22, [Score=235, Expect=4e-71]; ENSMUSG00000003053, Cyp2c29, cytochrome P450, family 2, subfamily c, polypeptide 29, [Score=234, Expect=1e-70]; ENSMUSG00000060407, Cyp2a12, cytochrome P450, family 2, subfamily a, polypeptide 12, [Score=233, Expect=2e-70]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=232, Expect=5e-70]; ENSMUSG00000005547, Cyp2a5, cytochrome P450, family 2, subfamily a, polypeptide 5, [Score=230, Expect=4e-69]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [Score=229, Expect=9e-69]; ENSMUSG00000061740, Cyp2d22, cytochrome P450, family 2, subfamily d, polypeptide 22, [Score=229, Expect=6e-69]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=201, Expect=7e-58]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [Score=222, Expect=1e-66]} {Smed: dd_Smed_v6_5344_0_6, dd_Smed_v6_5344_0_6, [Score=206, Expect=2e-60]} {RNA1509_10048, RNA1509_26828} {RNA1310_15951, RNA1509_10048, RNA1509_26828} {RNA1509_10048, RNA1509_26828, RNA815_5705}
23. MligTC455_26914 1138 23.71 Mlig455_061108

Neo: -

Age: logFC(26M/2M)=2.088

Region-enriched R3: 2.065/0.00064

 4.338 0.823 0.871 0.818 - 0.857 0.969 Mlig455_061108 {REF} {Length: 2873} {Pfam: Fibronectin type III domain [PF00041.23, score=95.7]} {Mouse: ENSMUSG00000026193, Fn1, fibronectin 1, [Score=49.7, Expect=1e-05]} {RNA1509_23726, RNA1509_43838, RNA1509_45309, RNA1509_5914} {RNA1310_11509.1, RNA1509_23726, RNA1509_43838, RNA1509_45309, RNA1509_5914} {RNA1509_23726, RNA1509_43838, RNA1509_45309, RNA1509_5914, RNA815_4107}
24. MligTC455_52159 5039 104.98 Mlig455_022930

Neo: -

Age: logFC(26M/2M)=-1.171

Region-enriched R3: 2.011/0.00288

 CALM3 4.269 0.786 - 0.915 0.804 0.802 0.962 Mlig455_022930 {REF} {Length: 1221} {Pfam: EF hand [PF00036.34, score=110.8]; EF-hand domain pair [PF13499.8, score=103.6]; EF-hand domain pair [PF13833.8, score=88.4]; EF hand [PF13202.8, score=87.3]; EF-hand domain [PF13405.8, score=76.4]; EF-hand domain [PF14658.8, score=35.7]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=34.5]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=32.0]; Dockerin type I domain [PF00404.20, score=27.9]; EF-hand domain [PF08976.13, score=20.6]; GYF domain 2 [PF14237.8, score=19.3]} {Human: ENSG00000160014, CALM3, calmodulin 3, [Score=133, Expect=4e-40]; ENSG00000198668, CALM1, calmodulin 1, [Score=133, Expect=4e-40]; ENSG00000143933, CALM2, calmodulin 2, [Score=133, Expect=4e-40]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=133, Expect=3e-40]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=133, Expect=3e-40]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=133, Expect=3e-40]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=129, Expect=6e-39]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=129, Expect=8e-39]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=129, Expect=6e-39]} {RNA1509_24239, RNA1509_33140, RNA1509_4775, RNA1509_8044} {RNA1310_32140.1, RNA1509_24239, RNA1509_33140, RNA1509_4775, RNA1509_8044} {RNA1509_24239, RNA1509_33140, RNA1509_4775, RNA1509_8044, RNA815_3424.1}
25. MligTC455_21830 5295 110.31 Mlig455_014095

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.481

Region-enriched R3: 1.429/0.00231
Region-enriched R4: 1.366/0.01008
Region-enriched R5: 1.005/0.03133

 YDJC 4.266 0.725 0.854 - 0.978 0.853 0.856 Mlig455_014095 {REF} {Length: 1807} {TRANSSPLICED} {Pfam: YdjC-like protein [PF04794.14, score=165.2]} {Human: ENSG00000161179, YDJC, YdjC chitooligosaccharide deacetylase homolog, [RH, Score=164, Expect=2e-47]} {Mouse: ENSMUSG00000041774, Ydjc, YdjC homolog (bacterial), [RH, Score=172, Expect=7e-51]} {Smed: dd_Smed_v6_65631_0_1, dd_Smed_v6_65631_0_1, [RH, Score=68.9, Expect=2e-14]} {RNA1509_18855, RNA1509_29693, RNA1509_42768} {RNA1310_36996, RNA1509_18855, RNA1509_29693, RNA1509_42768} {RNA1509_18855, RNA1509_29693, RNA1509_42768, RNA815_4988.1}
26. MligTC455_43334 7286 151.78 Mlig455_054088

Neo: -

Age: logFC(26M/2M)=0.327

Region-enriched R3: 1.908/0.00014

 CTSB 4.222 0.741 0.841 - 0.953 0.819 0.868 Mlig455_054088 {REF} {Length: 2579} {Pfam: Papain family cysteine protease [PF00112.25, score=227.1]; Peptidase family C1 propeptide [PF08127.15, score=44.5]} {Human: ENSG00000164733, CTSB, cathepsin B, [RH, Score=387, Expect=1e-134]} {Mouse: ENSMUSG00000021939, Ctsb, cathepsin B, [RH, Score=387, Expect=1e-134]} {Dmel: FBgn0030521, CtsB1, Cathepsin B1, [RH, Score=369, Expect=2e-127]} {Celegans: WBGene00010204, F57F5.1, [RH, Score=338, Expect=1e-115]} {Smed: dd_Smed_v6_81_0_1, dd_Smed_v6_81_0_1, [RH, Score=424, Expect=2e-149]} {RNA1509_448} {RNA1310_24539, RNA1509_448} {RNA1509_448, RNA815_4531}
27. MligTC455_41983 2249 46.86 Mlig455_014572

Neo: -

Age: -

Region-enriched R4: 2.314/0.00000
Region-enriched R3: 1.500/0.00235
Region-enriched R6: 1.362/0.01872
Region-enriched R5: 1.347/0.00318

 BHMT 4.221 0.784 - 0.733 0.937 0.810 0.957 Mlig455_014572 {REF} {Length: 2550} {Pfam: Homocysteine S-methyltransferase [PF02574.18, score=161.0]} {Human: ENSG00000145692, BHMT, betaine--homocysteine S-methyltransferase, [RH, Score=542, Expect=0.0]} {Mouse: ENSMUSG00000069324, Gm5096, predicted gene 5096, [RH, Score=545, Expect=0.0]; ENSMUSG00000074768, Bhmt, betaine-homocysteine methyltransferase, [RH, Score=545, Expect=0.0]} {Smed: dd_Smed_v6_873_0_1, dd_Smed_v6_873_0_1, [RH, Score=555, Expect=0.0]} {RNA1509_18954, RNA1509_57529} {RNA1310_18981.1, RNA1509_18954} {RNA1509_18954, RNA815_5900.2}
28. MligTC455_21829 5023 104.65 Mlig455_014094

Neo: -

Age: -

Region-enriched R4: 1.409/0.02548
Region-enriched R3: 1.341/0.03362

 4.203 0.751 0.879 - 0.958 0.883 0.732 Mlig455_014094 {REF} {Length: 3099} {Pfam: Ependymin [PF00811.20, score=62.5]} {RNA1509_29432} {RNA1310_26645, RNA1509_29432} {RNA1509_29432, RNA815_4988.2}
29. MligTC455_43333 11678 243.29 Mlig455_036055

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.186

Region-enriched R3: 1.916/0.00004
Region-enriched R6: 1.435/0.01562
Region-enriched R5: 1.079/0.03201

 CTSB 4.026 0.703 0.769 - 0.966 0.727 0.861 Mlig455_036055 {REF} {Length: 1907} {Pfam: Papain family cysteine protease [PF00112.25, score=227.2]; Peptidase family C1 propeptide [PF08127.15, score=44.5]} {Human: ENSG00000164733, CTSB, cathepsin B, [RH, Score=388, Expect=7e-135]} {Mouse: ENSMUSG00000021939, Ctsb, cathepsin B, [RH, Score=385, Expect=5e-134]} {Dmel: FBgn0030521, CtsB1, Cathepsin B1, [RH, Score=366, Expect=1e-126]} {Celegans: WBGene00010204, F57F5.1, [RH, Score=336, Expect=1e-114]} {Smed: dd_Smed_v6_81_0_1, dd_Smed_v6_81_0_1, [RH, Score=427, Expect=2e-150]} {RNA1509_2988, RNA1509_448} {RNA1310_24539, RNA1509_2988} {RNA1509_2988, RNA815_4531}
30. MligTC455_39169 881 18.35 Mlig455_063890

Neo: -

Age: -

Region-enriched R3: 3.017/0.00000

 ALDH2 3.73 0.896 0.970 - 0.927 - 0.937 Mlig455_063890 {REF} {Length: 2688} {Pfam: Aldehyde dehydrogenase family [PF00171.24, score=591.3]} {Human: ENSG00000111275, ALDH2, aldehyde dehydrogenase 2 family member, [RH, Score=777, Expect=0.0]; ENSG00000137124, ALDH1B1, aldehyde dehydrogenase 1 family member B1, [RH, Score=753, Expect=0.0]} {Mouse: ENSMUSG00000029455, Aldh2, aldehyde dehydrogenase 2, mitochondrial, [RH, Score=768, Expect=0.0]; ENSMUSG00000035561, Aldh1b1, aldehyde dehydrogenase 1 family, member B1, [RH, Score=749, Expect=0.0]} {Dmel: FBgn0012036, Aldh, Aldehyde dehydrogenase, [RH, Score=718, Expect=0.0]} {Celegans: WBGene00000107, alh-1, ALdehyde deHydrogenase, [RH, Score=725, Expect=0.0]} {Smed: dd_Smed_v6_1339_0_1, dd_Smed_v6_1339_0_1, [RH, Score=726, Expect=0.0]} {RNA1509_1186, RNA1509_20297} {RNA1310_3799.1, RNA1509_20297} {RNA1509_20297, RNA815_1286.1}
31. MligTC455_11650 1098 22.87 Mlig455_007133

Neo: -

Age: logFC(26M/2M)=1.455

Region-enriched R4: 2.055/0.00000
Region-enriched R3: 1.617/0.00001
Region-enriched R5: 1.032/0.00532

 3.686 - - 0.910 0.965 0.909 0.902 Mlig455_007133 {REF} {Length: 1372} {Pfam: Tyrosine phosphatase family [PF13350.8, score=133.9]; Tyrosine phosphatase family [PF03162.15, score=32.8]} {Smed: dd_Smed_v6_6110_0_1, dd_Smed_v6_6110_0_1, [RH, Score=96.3, Expect=2e-22]} {RNA1509_24412} {RNA1310_29199} {RNA815_14210.1}
32. MligTC455_45315 4773 99.43 Mlig455_037736

Neo: -

Age: -

 3.607 - 0.871 - 0.973 0.855 0.908 Mlig455_037736 {REF} {Length: 2269} {RNA1509_18494, RNA1509_5801} {RNA1310_12524.1, RNA1509_5801} {RNA1509_5801, RNA815_3944.1}
33. MligTC455_14767 2011 41.89 Mlig455_025056, Mlig455_025071

Neo: -

Age: logFC(26M/2M)=0.363

Region-enriched R3: 2.688/0.00000
Region-enriched R4: 2.096/0.00294
Region-enriched R5: 1.541/0.00872

 3.576 0.893 0.917 - - 0.810 0.956

Mlig455_025056 {REF} {Length: 1924} {Pfam: F5/8 type C domain [PF00754.27, score=68.1]} {Dmel: FBgn0030617, CG9095, [Score=49.7, Expect=4e-06]} {Smed: dd_Smed_v6_71482_0_1, dd_Smed_v6_71482_0_1, [RH, Score=65.9, Expect=2e-12]} {RNA1509_11049} {RNA1310_13321.1} {RNA815_5230.1}

Mlig455_025071 {REF} {Length: 2187} {Pfam: F5/8 type C domain [PF00754.27, score=67.5]} {Dmel: FBgn0030617, CG9095, [Score=49.7, Expect=4e-06]} {Smed: dd_Smed_v6_71482_0_1, dd_Smed_v6_71482_0_1, [RH, Score=65.9, Expect=2e-12]} {RNA1509_11049, RNA1509_6672} {RNA1310_13321.1, RNA1509_11049, RNA1509_6672} {RNA1509_11049, RNA1509_6672, RNA815_5230.1}
34. MligTC455_35632 6861 142.93 Mlig455_047206

Neo: -

Age: -

Region-enriched R3: 1.984/0.00032
Region-enriched R4: 1.605/0.01274
Region-enriched R5: 1.441/0.00908

 DHDH 3.533 - 0.710 - 0.987 0.888 0.948 Mlig455_047206 {REF} {Length: 1483} {Pfam: Oxidoreductase family, NAD-binding Rossmann fold [PF01408.24, score=86.6]; Oxidoreductase family, C-terminal alpha/beta domain [PF02894.19, score=32.8]} {Human: ENSG00000104808, DHDH, dihydrodiol dehydrogenase, [RH, Score=245, Expect=8e-79]} {Mouse: ENSMUSG00000011382, Dhdh, dihydrodiol dehydrogenase (dimeric), [RH, Score=247, Expect=1e-79]} {Dmel: FBgn0031418, CG3609, [Score=229, Expect=5e-73]} {Smed: dd_Smed_v6_7643_0_1, dd_Smed_v6_7643_0_1, [RH, Score=211, Expect=2e-66]} {RNA1509_4889} {RNA1310_24236} {RNA815_11111.1}
35. MligTC455_36113 1732 36.08 Mlig455_041129

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.669

Region-enriched R6: 1.868/0.00010
Region-enriched R4: 1.497/0.01253

 RGN 3.51 - 0.775 - 0.970 0.837 0.928 Mlig455_041129 {REF} {Length: 1164} {TRANSSPLICED} {Pfam: SMP-30/Gluconolactonase/LRE-like region [PF08450.14, score=221.4]; Two component regulator propeller [PF07494.13, score=25.8]; NHL repeat [PF01436.23, score=24.6]} {Human: ENSG00000130988, RGN, regucalcin, [RH, Score=184, Expect=8e-56]} {Mouse: ENSMUSG00000023070, Rgn, regucalcin, [RH, Score=189, Expect=6e-58]} {Dmel: FBgn0038257, smp-30, Senescence marker protein-30, [RH, Score=161, Expect=3e-47]} {Smed: dd_Smed_v6_3808_0_1, dd_Smed_v6_3808_0_1, [RH, Score=176, Expect=6e-53]} {RNA1509_28387} {RNA1310_7497.2} {RNA815_8819.2}
36. MligTC455_50034 2671 55.65 Mlig455_000005

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.540

Region-enriched R3: 1.249/0.00057

 SPHK1 3.496 - - 0.771 0.958 0.854 0.913 Mlig455_000005 {REF} {Length: 2212} {Pfam: Diacylglycerol kinase catalytic domain [PF00781.26, score=70.4]} {Human: ENSG00000176170, SPHK1, sphingosine kinase 1, [Score=144, Expect=1e-37]} {Mouse: ENSMUSG00000057342, Sphk2, sphingosine kinase 2, [RH, Score=140, Expect=1e-35]} {Dmel: FBgn0030300, Sk1, Sphingosine kinase 1, [Score=134, Expect=1e-33]} {Celegans: WBGene00007918, sphk-1, Sphingosine kinase 1, [Score=114, Expect=1e-27]} {Smed: dd_Smed_v6_5736_0_1, dd_Smed_v6_5736_0_1, [Score=121, Expect=3e-30]} {RNA1509_19326} {RNA1310_4471, RNA1509_19326} {RNA1509_19326, RNA815_1161}
37. MligTC455_14276 2183 45.48 Mlig455_065037

Neo: -

Age: logFC(26M/2M)=0.489

 PLBD1 3.478 0.770 - - 0.972 0.856 0.880 Mlig455_065037 {REF} {Length: 2884} {Pfam: Phospholipase B [PF04916.15, score=514.0]} {Human: ENSG00000121316, PLBD1, phospholipase B domain containing 1, [RH, Score=462, Expect=1e-156]} {Mouse: ENSMUSG00000030214, Plbd1, phospholipase B domain containing 1, [RH, Score=478, Expect=2e-163]} {Dmel: FBgn0016031, lama, lamina ancestor, [Score=92.0, Expect=4e-19]} {Celegans: WBGene00008607, F09B12.3, Putative phospholipase B-like 2, [RH, Score=236, Expect=1e-69]} {Smed: dd_Smed_v6_485_0_1, dd_Smed_v6_485_0_1, [Score=209, Expect=7e-60]} {RNA1509_9263} {RNA1310_7896, RNA1509_9263} {RNA1509_9263, RNA815_2504}
38. MligTC455_19214 797 16.61 Mlig455_067480, Mlig455_067488

Neo: -

Age: logFC(26M/2M)=0.411

Region-enriched R4: 2.048/0.00458

 HSD11B1 3.461 0.807 0.776 - - 0.973 0.905

Mlig455_067480 {REF} {Length: 1095} {Pfam: short chain dehydrogenase [PF00106.27, score=63.8]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=42.8]} {Human: ENSG00000117594, HSD11B1, hydroxysteroid 11-beta dehydrogenase 1, [Score=83.6, Expect=1e-18]} {Mouse: ENSMUSG00000029311, Hsd17b11, hydroxysteroid (17-beta) dehydrogenase 11, [Score=59.7, Expect=2e-10]} {Dmel: FBgn0039043, CG17121, [Score=49.7, Expect=7e-07]} {RNA1509_28182} {RNA1310_27439} {RNA815_13316}

Mlig455_067488 {REF} {Length: 1390} {Pfam: short chain dehydrogenase [PF00106.27, score=128.2]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=83.0]; KR domain [PF08659.12, score=25.0]; Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [PF02882.21, score=18.0]} {Human: ENSG00000117594, HSD11B1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=158, Expect=4e-46]} {Mouse: ENSMUSG00000016194, Hsd11b1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=151, Expect=1e-43]} {Dmel: FBgn0051548, CG31548, [Score=80.9, Expect=2e-17]} {Celegans: WBGene00019885, R05D8.7, [Score=80.1, Expect=3e-17]} {Smed: dd_Smed_v6_3167_0_1, dd_Smed_v6_3167_0_1, [Score=71.6, Expect=2e-14]} {RNA1509_28182, RNA1509_29712, RNA1509_41682} {RNA1310_27439, RNA1509_28182, RNA1509_29712, RNA1509_41682} {RNA1509_28182, RNA1509_29712, RNA1509_41682, RNA815_13316}
39. MligTC455_45291 2427 50.57 Mlig455_024270

Neo: -

Age: -

Region-enriched R3: 1.846/0.00333

 SUSD2 3.441 0.838 - - 0.818 0.969 0.816 Mlig455_024270 {REF} {Length: 4363} {Pfam: AMOP domain [PF03782.19, score=54.3]; von Willebrand factor type D domain [PF00094.27, score=35.6]; Nidogen-like [PF06119.16, score=28.7]} {Human: ENSG00000099994, SUSD2, sushi domain containing 2, [Score=120, Expect=4e-27]} {Mouse: ENSMUSG00000006342, Susd2, sushi domain containing 2, [RH, Score=134, Expect=1e-31]} {Dmel: FBgn0051004, mesh, [RH, Score=159, Expect=4e-39]} {RNA1509_10841, RNA1509_1220, RNA1509_24159, RNA1509_25642, RNA1509_33791, RNA1509_46716} {RNA1310_2718.1, RNA1509_10841, RNA1509_1220, RNA1509_24159, RNA1509_25642, RNA1509_33791, RNA1509_46716} {RNA1509_10841, RNA1509_1220, RNA1509_24159, RNA1509_25642, RNA1509_33791, RNA1509_46716, RNA815_500}
40. MligTC455_45290 2414 50.29 Mlig455_024268

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=8.245

Region-enriched R3: 1.852/0.00444

 3.433 0.838 - - 0.818 0.968 0.809 Mlig455_024268 {REF} {Length: 1621} {RNA1509_33791} {RNA1310_2718.1} {RNA815_500}
41. MligTC455_20359 2045 42.61 Mlig455_051099

Neo: -

Age: -

Region-enriched R3: 1.714/0.00720

 SLC15A1 3.421 0.722 0.891 - - 0.953 0.855 Mlig455_051099 {REF} {Length: 3010} {Pfam: POT family [PF00854.23, score=282.9]; Major Facilitator Superfamily [PF07690.18, score=26.5]; MFS/sugar transport protein [PF13347.8, score=17.7]} {Human: ENSG00000088386, SLC15A1, solute carrier family 15 member 1, [Score=351, Expect=7e-110]} {Mouse: ENSMUSG00000025557, Slc15a1, solute carrier family 15 (oligopeptide transporter), member 1, [Score=347, Expect=1e-108]; ENSMUSG00000022899, Slc15a2, solute carrier family 15 (H+/peptide transporter), member 2, [Score=332, Expect=2e-102]} {Dmel: FBgn0028491, CG2930, [Score=291, Expect=2e-86]} {Celegans: WBGene00003877, pept-1, Peptide transporter family 1, [RH, Score=271, Expect=4e-79]} {Smed: dd_Smed_v6_4941_0_1, dd_Smed_v6_4941_0_1, [RH, Score=449, Expect=1e-148]} {RNA1509_12523, RNA1509_2288, RNA1509_5660, RNA1509_7670, RNA1509_9453} {RNA1310_5104.2, RNA1509_12523, RNA1509_2288, RNA1509_5660, RNA1509_7670, RNA1509_9453} {RNA1509_12523, RNA1509_2288, RNA1509_5660, RNA1509_7670, RNA1509_9453, RNA815_1763.1}
42. MligTC455_20353 17917 373.27 Mlig455_013260, Mlig455_013275, Mlig455_013349

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.424

Region-enriched R3: 2.278/0.00008
Region-enriched R4: 1.727/0.01391

 3.367 - 0.755 - 0.890 0.953 0.769

Mlig455_013260 {REF} {Length: 1502} {RNA1509_60036, RNA1509_670} {RNA1310_18395, RNA1509_60036} {RNA1509_60036, RNA815_8767}

Mlig455_013275 {REF} {Length: 1323} {RNA1509_670} {RNA1310_18395} {RNA815_8767}

Mlig455_013349 {REF} {Length: 1540} {RNA1509_51207, RNA1509_57783, RNA1509_670} {RNA1310_18395, RNA1509_51207, RNA1509_57783, RNA1509_670} {RNA1509_51207, RNA1509_57783, RNA1509_670, RNA815_8767}
43. MligTC455_38390 5253 109.43 Mlig455_012923

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.677

Region-enriched R3: 1.882/0.01066

 KREMEN1 3.367 0.744 0.848 0.821 - - 0.954 Mlig455_012923 {REF} {Length: 983} {Pfam: WSC domain [PF01822.21, score=64.1]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=55.8, Expect=1e-09]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=53.5, Expect=6e-09]} {Dmel: FBgn0046685, Wsck, [Score=57.8, Expect=1e-10]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=44.7, Expect=4e-06]} {RNA1509_11244} {RNA1310_67645} {RNA815_21733.1}
44. MligTC455_25519 1173 24.43 Mlig455_012881

Neo: -

Age: logFC(26M/2M)=-0.253

Region-enriched R3: 1.409/0.00967

 SLC13A3 3.35 0.736 0.847 - - 0.815 0.952 Mlig455_012881 {REF} {Length: 4943} {Pfam: Sodium:sulfate symporter transmembrane region [PF00939.21, score=346.8]; Citrate transporter [PF03600.18, score=107.6]} {Human: ENSG00000158296, SLC13A3, solute carrier family 13 member 3, [Score=411, Expect=4e-135]; ENSG00000141485, SLC13A5, solute carrier family 13 member 5, [Score=410, Expect=6e-135]; ENSG00000007216, SLC13A2, solute carrier family 13 member 2, [Score=393, Expect=4e-128]} {Mouse: ENSMUSG00000001095, Slc13a2, solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2, [Score=402, Expect=6e-132]; ENSMUSG00000029700, Slc13a1, solute carrier family 13 (sodium/sulfate symporters), member 1, [Score=401, Expect=1e-131]; ENSMUSG00000018459, Slc13a3, solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3, [Score=386, Expect=1e-125]} {Dmel: FBgn0036816, Indy, I'm not dead yet, [Score=303, Expect=5e-94]} {Celegans: WBGene00003517, nac-1, Sodium-dependent low-affinity dicarboxylate transporter 1, [Score=334, Expect=4e-106]} {Smed: dd_Smed_v6_15654_0_1, dd_Smed_v6_15654_0_1, [Score=350, Expect=3e-112]} {RNA1509_17695, RNA1509_5950} {RNA1310_9467.1, RNA1509_17695, RNA1509_5950} {RNA1509_17695, RNA1509_5950, RNA815_3472}
45. MligTC455_39549 1949 40.61 Mlig455_004602

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=1.654

Region-enriched R5: 2.577/0.00276
Region-enriched R4: 2.372/0.03782

 3.337 - 0.766 - 0.972 0.739 0.860 Mlig455_004602 {REF} {Length: 3069} {Pfam: Universal stress protein family [PF00582.28, score=98.4]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=106, Expect=1e-29]} {RNA1509_6489} {RNA1310_12949, RNA1509_6489} {RNA1509_6489, RNA815_11224}
46. MligTC455_37466 1949 40.61 Mlig455_031186

Neo: -

Age: Down-Down-Up

Region-enriched R3: 1.619/0.00008

 ARHGEF10 3.265 0.771 0.729 - 0.955 0.810 - Mlig455_031186 {REF} {Length: 5352} {Pfam: RhoGEF domain [PF00621.22, score=105.9]; WD40 repeated domain [PF19056.2, score=87.7]; PH domain [PF19057.2, score=32.3]} {Human: ENSG00000274726, ARHGEF10, Rho guanine nucleotide exchange factor 10, [RH, Score=289, Expect=7e-80]; ENSG00000104728, ARHGEF10, Rho guanine nucleotide exchange factor 10, [RH, Score=289, Expect=7e-80]} {Mouse: ENSMUSG00000071176, Arhgef10, Rho guanine nucleotide exchange factor (GEF) 10, [RH, Score=301, Expect=5e-84]} {Dmel: FBgn0263706, CG43658, [RH, Score=249, Expect=8e-67]} {Celegans: WBGene00019832, osg-1, Rho guanine nucleotide exchange factor osg-1, [Score=115, Expect=1e-25]} {Smed: dd_Smed_v6_2922_0_1, dd_Smed_v6_2922_0_1, [Score=112, Expect=7e-25]} {RNA1509_2853} {RNA1310_2593.1} {RNA815_1265}
47. MligTC455_40311 795 16.57 Mlig455_005646

Neo: -

Age: logFC(26M/2M)=-1.077

Region-enriched R4: 2.244/0.00079
Region-enriched R5: 1.789/0.00084

 CYP2J2 2.702 - - - 0.957 0.937 0.808 Mlig455_005646 {REF} {Length: 2326} {Pfam: Cytochrome P450 [PF00067.24, score=345.0]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [RH, Score=303, Expect=4e-97]} {Mouse: ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=280, Expect=2e-88]; ENSMUSG00000042248, Cyp2c37, cytochrome P450, family 2. subfamily c, polypeptide 37, [RH, Score=280, Expect=1e-88]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=278, Expect=3e-87]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=276, Expect=8e-87]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [RH, Score=272, Expect=3e-85]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=271, Expect=1e-84]; ENSMUSG00000054827, Cyp2c50, cytochrome P450, family 2, subfamily c, polypeptide 50, [RH, Score=270, Expect=1e-84]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=270, Expect=2e-84]; ENSMUSG00000032808, Cyp2c38, cytochrome P450, family 2, subfamily c, polypeptide 38, [RH, Score=267, Expect=2e-83]; ENSMUSG00000025003, Cyp2c39, cytochrome P450, family 2, subfamily c, polypeptide 39, [RH, Score=266, Expect=6e-83]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=223, Expect=5e-66]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [RH, Score=249, Expect=1e-76]} {Smed: dd_Smed_v6_4449_0_1, dd_Smed_v6_4449_0_1, [Score=260, Expect=8e-81]} {RNA1509_32472} {RNA1310_10280} {RNA815_4805}
48. MligTC455_31670 1807 37.64 Mlig455_042472

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.652

Region-enriched R4: 2.167/0.00909
Region-enriched R3: 2.148/0.00292

 2.701 - 0.838 - - 0.913 0.950 Mlig455_042472 {REF} {Length: 957} {RNA1509_3304, RNA1509_56059, RNA1509_6047} {RNA1310_18437, RNA1509_3304, RNA1509_56059, RNA1509_6047} {RNA1509_3304, RNA1509_56059, RNA1509_6047, RNA815_7167.1}
49. MligTC455_44102 5169 107.69 Mlig455_011991

Neo: -

Age: logFC(26M/2M)=0.278

Region-enriched R3: 1.948/0.00360
Region-enriched R4: 1.688/0.02863

 HPGDS 2.693 - - - 0.893 0.832 0.968 Mlig455_011991 {REF} {Length: 1746} {Pfam: Glutathione S-transferase, C-terminal domain [PF14497.8, score=43.5]; Glutathione S-transferase, N-terminal domain [PF02798.22, score=42.8]; Glutathione S-transferase, N-terminal domain [PF13417.8, score=22.6]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=20.1]; Glutathione S-transferase, N-terminal domain [PF13409.8, score=19.1]} {Human: ENSG00000163106, HPGDS, hematopoietic prostaglandin D synthase, [Score=67.8, Expect=2e-13]} {Mouse: ENSMUSG00000025934, Gsta3, glutathione S-transferase, alpha 3, [Score=62.4, Expect=1e-11]; ENSMUSG00000032348, Gsta4, glutathione S-transferase, alpha 4, [Score=60.5, Expect=6e-11]; ENSMUSG00000029919, Hpgds, hematopoietic prostaglandin D synthase, [Score=60.5, Expect=5e-11]} {Celegans: WBGene00001756, gst-8, Probable glutathione S-transferase 8, [Score=84.0, Expect=5e-20]} {Smed: dd_Smed_v6_20_0_1, dd_Smed_v6_20_0_1, [Score=115, Expect=4e-32]} {RNA1509_2160, RNA1509_26612, RNA1509_28516, RNA1509_5091, RNA1509_6359} {RNA1310_14959.1, RNA1509_2160, RNA1509_26612, RNA1509_28516, RNA1509_5091, RNA1509_6359} {RNA1509_2160, RNA1509_26612, RNA1509_28516, RNA1509_5091, RNA1509_6359, RNA815_7403}
50. MligTC455_35614 3756 78.26 Mlig455_047904, Mlig455_047993

Neo: -

Age: -

Region-enriched R4: 1.029/0.04541

 A1CF 2.681 - - - 0.962 0.863 0.856

Mlig455_047904 {REF} {Length: 4469} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=118.8]; RNA recognition motif [PF16367.7, score=21.9]} {Human: ENSG00000148584, A1CF, APOBEC1 complementation factor, [RH, Score=429, Expect=1e-140]; ENSG00000163694, RBM47, RNA binding motif protein 47, [RH, Score=415, Expect=6e-136]} {Mouse: ENSMUSG00000070780, Rbm47, RNA binding motif protein 47, [RH, Score=416, Expect=1e-136]; ENSMUSG00000052595, A1cf, APOBEC1 complementation factor, [RH, Score=416, Expect=1e-135]} {Dmel: FBgn0038826, Syp, Syncrip, [Score=335, Expect=5e-105]} {Celegans: WBGene00002000, hrp-2, HnRNP A1 homolog, [Score=276, Expect=3e-82]} {Smed: dd_Smed_v6_2228_0_1, dd_Smed_v6_2228_0_1, [RH, Score=452, Expect=7e-149]} {RNA1509_2682, RNA1509_40750} {RNA1310_1897.2, RNA1509_40750} {RNA1509_40750, RNA815_7771.1}

Mlig455_047993 {REF} {Length: 4380} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=115.7]; RNA recognition motif [PF16367.7, score=21.8]} {Human: ENSG00000148584, A1CF, APOBEC1 complementation factor, [RH, Score=430, Expect=1e-140]; ENSG00000163694, RBM47, RNA binding motif protein 47, [RH, Score=415, Expect=7e-136]} {Mouse: ENSMUSG00000052595, A1cf, APOBEC1 complementation factor, [RH, Score=416, Expect=2e-135]; ENSMUSG00000070780, Rbm47, RNA binding motif protein 47, [RH, Score=416, Expect=1e-136]} {Dmel: FBgn0038826, Syp, Syncrip, [Score=335, Expect=5e-105]} {Celegans: WBGene00002000, hrp-2, HnRNP A1 homolog, [Score=275, Expect=3e-82]} {Smed: dd_Smed_v6_2228_0_1, dd_Smed_v6_2228_0_1, [RH, Score=452, Expect=6e-149]} {RNA1509_2682} {RNA1310_1897.2, RNA1509_2682} {RNA1509_2682, RNA815_7771.1}
51. MligTC455_35666 3073 64.02 Mlig455_024866

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.297

Region-enriched R3: 1.613/0.00014

 AC099489.1 2.674 - - - 0.956 0.835 0.883 Mlig455_024866 {REF} {Length: 12799} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=87.8]; Domain of unknown function (DUF1943) [PF09172.13, score=66.5]; von Willebrand factor type D domain [PF00094.27, score=29.7]} {Human: ENSG00000188897, AC099489.1, vitellogenin, [Score=128, Expect=3e-28]} {Dmel: FBgn0032136, Apoltp, Apolipoprotein lipid transfer particle, [Score=67.8, Expect=3e-10]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=94.7, Expect=1e-18]} {RNA1509_27087} {RNA1310_1234.2} {RNA815_55}
52. MligTC455_35613 1908 39.74 Mlig455_047833

Neo: -

Age: -

Region-enriched R4: 1.137/0.03007

 A1CF 2.666 - - - 0.953 0.866 0.847 Mlig455_047833 {REF} {Length: 5820} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=114.5]; RNA recognition motif [PF16367.7, score=22.1]} {Human: ENSG00000148584, A1CF, APOBEC1 complementation factor, [RH, Score=430, Expect=5e-141]; ENSG00000163694, RBM47, RNA binding motif protein 47, [RH, Score=416, Expect=4e-136]} {Mouse: ENSMUSG00000070780, Rbm47, RNA binding motif protein 47, [RH, Score=417, Expect=7e-137]; ENSMUSG00000052595, A1cf, APOBEC1 complementation factor, [RH, Score=417, Expect=6e-136]; ENSMUSG00000033882, Rbm46, RNA binding motif protein 46, [RH, Score=397, Expect=6e-129]} {Dmel: FBgn0038826, Syp, Syncrip, [Score=337, Expect=1e-105]} {Celegans: WBGene00002000, hrp-2, HnRNP A1 homolog, [Score=277, Expect=8e-83]} {Smed: dd_Smed_v6_2228_0_1, dd_Smed_v6_2228_0_1, [RH, Score=454, Expect=9e-150]} {RNA1509_2682} {RNA1310_1897.3} {RNA815_9253.1}
53. MligTC455_38363 2457 51.19 Mlig455_045500, Mlig455_065739

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.377

Region-enriched R3: 1.866/0.00436
Region-enriched R6: 1.855/0.01251
Region-enriched R5: 1.276/0.04355

Regeneration-upregulated TP: 3.564

Regeneration-enriched TP: 3.564

 AADAC 2.654 - 0.768 - 0.934 - 0.952

Mlig455_045500 {REF} {Length: 2281} {Pfam: alpha/beta hydrolase fold [PF07859.15, score=144.9]; Carboxylesterase family [PF00135.30, score=29.3]} {Human: ENSG00000114771, AADAC, arylacetamide deacetylase, [Score=109, Expect=7e-26]; ENSG00000261846, AADACL2, arylacetamide deacetylase like 2, [Score=107, Expect=5e-25]; ENSG00000197953, AADACL2, arylacetamide deacetylase like 2, [Score=107, Expect=5e-25]} {Mouse: ENSMUSG00000090527, Gm5538, predicted gene 5538, [Score=117, Expect=9e-29]; ENSMUSG00000095522, Gm8298, predicted gene 8298, [Score=114, Expect=1e-27]} {Dmel: FBgn0034491, Hsl, Hormone-sensitive lipase, [Score=82.4, Expect=2e-16]} {Celegans: WBGene00012810, nceh-1, Neutral Cholesterol Ester Hydrolase homolog, [Score=114, Expect=6e-28]} {Smed: dd_Smed_v6_4674_0_1, dd_Smed_v6_4674_0_1, [Score=101, Expect=1e-23]} {RNA1509_7598} {RNA1310_15560.1, RNA1509_7598} {RNA1509_7598, RNA815_8354}

Mlig455_065739 {REF} {Length: 1875} {Pfam: alpha/beta hydrolase fold [PF07859.15, score=144.8]; Carboxylesterase family [PF00135.30, score=29.3]} {Human: ENSG00000114771, AADAC, arylacetamide deacetylase, [Score=109, Expect=8e-26]; ENSG00000261846, AADACL2, arylacetamide deacetylase like 2, [Score=107, Expect=5e-25]; ENSG00000197953, AADACL2, arylacetamide deacetylase like 2, [Score=107, Expect=5e-25]} {Mouse: ENSMUSG00000090527, Gm5538, predicted gene 5538, [Score=117, Expect=9e-29]; ENSMUSG00000095522, Gm8298, predicted gene 8298, [Score=113, Expect=2e-27]} {Dmel: FBgn0034491, Hsl, Hormone-sensitive lipase, [Score=82.0, Expect=2e-16]} {Celegans: WBGene00012810, nceh-1, Neutral Cholesterol Ester Hydrolase homolog, [Score=114, Expect=1e-27]} {Smed: dd_Smed_v6_4674_0_1, dd_Smed_v6_4674_0_1, [Score=101, Expect=1e-23]} {RNA1509_7598} {RNA1310_15560.1} {RNA815_8354}
54. MligTC455_41283 1026 21.38 Mlig455_056291

Neo: -

Age: Down-Up-Up

Region-enriched R3: 2.480/0.00000
Region-enriched R4: 1.642/0.01172
Region-enriched R5: 1.330/0.01324

 2.644 0.867 0.820 - - - 0.957 Mlig455_056291 {REF} {Length: 1075} {RNA1509_3034} {RNA1310_55537, RNA1509_3034} {RNA1509_3034, RNA815_28451}
55. MligTC455_19734 641 13.36 Mlig455_022085

Neo: -

Age: logFC(26M/2M)=0.429

Region-enriched R3: 1.841/0.00032
Region-enriched R5: 1.053/0.04479

 SORD 2.58 0.793 0.835 - - - 0.952 Mlig455_022085 {REF} {Length: 1452} {Pfam: Alcohol dehydrogenase GroES-like domain [PF08240.14, score=87.1]; Glucose dehydrogenase C-terminus [PF16912.7, score=53.4]; Zinc-binding dehydrogenase [PF00107.28, score=35.7]} {Human: ENSG00000140263, SORD, sorbitol dehydrogenase, [Score=83.6, Expect=2e-17]} {Mouse: ENSMUSG00000027227, Sord, sorbitol dehydrogenase, [Score=76.6, Expect=4e-15]} {Dmel: FBgn0022359, Sodh-2, Sorbitol dehydrogenase-2, [Score=87.4, Expect=5e-19]} {Celegans: WBGene00011003, R04B5.5, [Score=106, Expect=5e-26]} {Smed: dd_Smed_v6_1002_0_1, dd_Smed_v6_1002_0_1, [Score=84.0, Expect=4e-18]} {RNA1509_22659} {RNA1310_24339} {RNA815_10635.2}
56. MligTC455_27869 8765 182.6 Mlig455_051857, Mlig455_051868, Mlig455_051893

Neo: -

Age: Down-Down-Up

Region-enriched R3: 2.214/0.00040
Region-enriched R5: 1.603/0.01133

 ANPEP 2.57 0.820 0.791 - - 0.959 -

Mlig455_051857 {REF} {Length: 3680} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=260.1]; Peptidase family M1 domain [PF01433.22, score=238.0]; Peptidase M1 N-terminal domain [PF17900.3, score=137.9]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=560, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [RH, Score=546, Expect=6e-179]} {Dmel: FBgn0039640, CG14516, [RH, Score=536, Expect=1e-174]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=405, Expect=2e-125]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=599, Expect=0.0]} {RNA1509_5196} {RNA1310_2955.1} {RNA815_759.2}

Mlig455_051868 {REF} {Length: 4344} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=259.5]; Peptidase family M1 domain [PF01433.22, score=234.1]; Peptidase M1 N-terminal domain [PF17900.3, score=137.9]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=552, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [Score=542, Expect=4e-177]} {Dmel: FBgn0039640, CG14516, [RH, Score=529, Expect=7e-172]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=406, Expect=1e-125]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=595, Expect=0.0]} {RNA1509_5196} {RNA1310_2955.1} {RNA815_759.2}

Mlig455_051893 {REF} {Length: 4373} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=260.1]; Peptidase family M1 domain [PF01433.22, score=236.2]; Peptidase M1 N-terminal domain [PF17900.3, score=137.9]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=558, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [RH, Score=545, Expect=3e-178]} {Dmel: FBgn0039640, CG14516, [RH, Score=533, Expect=2e-173]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=405, Expect=2e-125]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=596, Expect=0.0]} {RNA1509_5196} {RNA1310_2955.1} {RNA815_759.2}
57. MligTC455_26632 2223 46.31 Mlig455_010979

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.932

Region-enriched R3: 1.352/0.01651

 ASGR2 2.508 0.704 - - 0.950 - 0.854 Mlig455_010979 {REF} {Length: 3718} {Pfam: Lectin C-type domain [PF00059.23, score=51.8]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=29.4]} {Human: ENSG00000161944, ASGR2, asialoglycoprotein receptor 2, [Score=53.1, Expect=6e-07]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [Score=62.0, Expect=2e-09]; ENSMUSG00000020695, Mrc2, mannose receptor, C type 2, [Score=60.5, Expect=6e-09]} {Dmel: FBgn0029697, CG15570, [Score=82.4, Expect=7e-16]} {Celegans: WBGene00020585, clec-178, C-type LECtin, [Score=57.4, Expect=2e-09]} {Smed: dd_Smed_v6_1489_0_1, dd_Smed_v6_1489_0_1, [Score=48.5, Expect=7e-06]} {RNA1509_10049, RNA1509_1147, RNA1509_39537, RNA1509_48412} {RNA1310_25013.1, RNA1509_10049, RNA1509_1147, RNA1509_39537, RNA1509_48412} {RNA1509_10049, RNA1509_1147, RNA1509_39537, RNA1509_48412, RNA815_11727}
58. MligTC455_04645 3218 67.03 Mlig455_070885

Neo: -

Age: logFC(26M/2M)=0.309

Region-enriched R3: 1.082/0.00299

 CMBL 2.441 - 0.731 - 0.958 0.752 - Mlig455_070885 {REF} {Length: 1230} {Pfam: Dienelactone hydrolase family [PF01738.20, score=58.5]; alpha/beta hydrolase fold [PF00561.22, score=18.7]} {Human: ENSG00000164237, CMBL, carboxymethylenebutenolidase homolog, [RH, Score=74.7, Expect=2e-15]} {Mouse: ENSMUSG00000022235, Cmbl, carboxymethylenebutenolidase-like (Pseudomonas), [RH, Score=79.0, Expect=4e-17]} {Smed: dd_Smed_v6_2062_0_1, dd_Smed_v6_2062_0_1, [Score=130, Expect=7e-37]} {RNA1509_4080} {RNA1310_26918, RNA1509_4080} {RNA1509_4080, RNA815_11993}
59. MligTC455_36082 1063 22.14 Mlig455_040337

Neo: -

Age: logFC(26M/2M)=-0.499

Region-enriched R4: 3.060/0.00000
Region-enriched R3: 2.482/0.00000
Region-enriched R5: 2.159/0.00000

 2.402 - 0.748 - 0.701 - 0.953 Mlig455_040337 {REF} {Length: 3101} {Pfam: Transforming growth factor beta like domain [PF00019.22, score=47.9]} {RNA1509_22478, RNA1509_5434} {RNA1310_5336, RNA1509_22478} {RNA1509_22478, RNA815_1739.1}
60. MligTC455_31506 586 12.2 Mlig455_059744

Neo: -

Age: -

Region-enriched R4: 2.875/0.00022
Region-enriched R3: 2.468/0.00160
Region-enriched R5: 2.189/0.00308

 DDO 1.763 - - - 0.952 0.811 - Mlig455_059744 {REF} {Length: 2018} {Pfam: FAD dependent oxidoreductase [PF01266.26, score=129.1]} {Human: ENSG00000203797, DDO, D-aspartate oxidase, [RH, Score=218, Expect=1e-67]; ENSG00000110887, DAO, D-amino acid oxidase, [RH, Score=209, Expect=1e-64]} {Mouse: ENSMUSG00000042096, Dao, D-amino acid oxidase, [RH, Score=216, Expect=3e-67]; ENSMUSG00000063428, Ddo, D-aspartate oxidase, [RH, Score=216, Expect=1e-67]} {Dmel: FBgn0031860, CG11236, [RH, Score=211, Expect=6e-66]} {Celegans: WBGene00022076, daao-1, D-amino-acid oxidase, [Score=174, Expect=1e-51]} {Smed: dd_Smed_v6_3560_0_1, dd_Smed_v6_3560_0_1, [RH, Score=246, Expect=2e-79]} {RNA1509_1569} {RNA1310_11182} {RNA815_6961}
61. MligTC455_43948 3488 72.67 Mlig455_002834, Mlig455_002839

Neo: -

Age: logFC(26M/2M)=-0.402

Region-enriched R5: 1.557/0.01497

 SLC32A1 1.742 0.751 - - 0.991 - -

Mlig455_002834 {REF} {Length: 2083} {Pfam: Transmembrane amino acid transporter protein [PF01490.20, score=180.6]} {Human: ENSG00000101438, SLC32A1, solute carrier family 32 member 1, [Score=183, Expect=6e-51]} {Mouse: ENSMUSG00000037771, Slc32a1, solute carrier family 32 (GABA vesicular transporter), member 1, [Score=182, Expect=7e-51]} {Dmel: FBgn0033911, VGAT, Vesicular GABA Transporter, [Score=178, Expect=4e-49]} {Celegans: WBGene00006783, unc-47, Vesicular GABA transporter, [Score=189, Expect=6e-54]} {Smed: dd_Smed_v6_20353_0_1, dd_Smed_v6_20353_0_1, [RH, Score=382, Expect=2e-128]} {RNA1509_6347} {RNA1310_11411, RNA1509_6347} {RNA1509_6347, RNA815_4946}

Mlig455_002839 {REF} {Length: 1987} {Pfam: Transmembrane amino acid transporter protein [PF01490.20, score=180.6]} {Human: ENSG00000101438, SLC32A1, solute carrier family 32 member 1, [Score=183, Expect=6e-51]} {Mouse: ENSMUSG00000037771, Slc32a1, solute carrier family 32 (GABA vesicular transporter), member 1, [Score=182, Expect=7e-51]} {Dmel: FBgn0033911, VGAT, Vesicular GABA Transporter, [Score=178, Expect=4e-49]} {Celegans: WBGene00006783, unc-47, Vesicular GABA transporter, [Score=189, Expect=6e-54]} {Smed: dd_Smed_v6_20353_0_1, dd_Smed_v6_20353_0_1, [RH, Score=382, Expect=2e-128]} {RNA1509_24687, RNA1509_28188, RNA1509_6347} {RNA1310_11411, RNA1509_24687, RNA1509_28188} {RNA1509_24687, RNA1509_28188, RNA815_4946}
62. MligTC455_19994 1390 28.95 Mlig455_028907

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.187

Region-enriched R5: 2.402/0.00000
Region-enriched R4: 2.251/0.00013

 ABCD4 1.724 - - - 0.950 - 0.774 Mlig455_028907 {REF} {Length: 2927} {TRANSSPLICED} {Pfam: ABC transporter transmembrane region 2 [PF06472.17, score=188.5]; ABC transporter [PF00005.29, score=59.3]; AAA domain [PF13401.8, score=19.2]} {Human: ENSG00000119688, ABCD4, ATP binding cassette subfamily D member 4, [RH, Score=401, Expect=2e-131]} {Mouse: ENSMUSG00000021240, Abcd4, ATP-binding cassette, sub-family D (ALD), member 4, [RH, Score=402, Expect=5e-132]} {Dmel: FBgn0031069, Pmp70, Peroxisomal Membrane Protein 70 kDa, [Score=159, Expect=7e-41]} {Celegans: WBGene00004060, pmp-3, Peroxisomal Membrane Protein related, [RH, Score=320, Expect=1e-99]} {Smed: dd_Smed_v6_8535_0_2, dd_Smed_v6_8535_0_2, [RH, Score=367, Expect=1e-118]} {RNA1509_19397, RNA1509_46393, RNA1509_49126} {RNA1310_5698.2, RNA1509_19397, RNA1509_46393, RNA1509_49126} {RNA1509_19397, RNA1509_46393, RNA1509_49126, RNA815_4418}
63. MligTC455_45293 1305 27.18 Mlig455_051600

Neo: -

Age: -

 SUSD2 0.966 - - - - 0.966 - Mlig455_051600 {REF} {Length: 5138} {Pfam: von Willebrand factor type D domain [PF00094.27, score=37.0]} {Human: ENSG00000099994, SUSD2, sushi domain containing 2, [Score=82.8, Expect=6e-16]} {Mouse: ENSMUSG00000006342, Susd2, sushi domain containing 2, [Score=100, Expect=7e-22]} {Dmel: FBgn0051004, mesh, [Score=102, Expect=3e-22]} {RNA1509_1220, RNA1509_1883, RNA1509_34687, RNA1509_36798, RNA1509_40605} {RNA1310_2718.1, RNA1509_1883, RNA1509_34687, RNA1509_36798, RNA1509_40605} {RNA1509_1883, RNA1509_34687, RNA1509_36798, RNA1509_40605, RNA815_500}
64. MligTC455_24363 1243 25.89 Mlig455_065691

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.713

 MOGAT2 0.962 - - - 0.962 - - Mlig455_065691 {REF} {Length: 3352} {TRANSSPLICED} {Pfam: Diacylglycerol acyltransferase [PF03982.15, score=385.5]} {Human: ENSG00000166391, MOGAT2, monoacylglycerol O-acyltransferase 2, [RH, Score=341, Expect=3e-111]; ENSG00000124003, MOGAT1, monoacylglycerol O-acyltransferase 1, [RH, Score=341, Expect=2e-111]} {Mouse: ENSMUSG00000052396, Mogat2, monoacylglycerol O-acyltransferase 2, [RH, Score=343, Expect=2e-112]; ENSMUSG00000012187, Mogat1, monoacylglycerol O-acyltransferase 1, [RH, Score=338, Expect=2e-110]} {Dmel: FBgn0033214, CG1941, [RH, Score=243, Expect=8e-74]} {Celegans: WBGene00019464, K07B1.4, [RH, Score=323, Expect=2e-104]} {Smed: dd_Smed_v6_4947_0_1, dd_Smed_v6_4947_0_1, [RH, Score=395, Expect=7e-133]} {RNA1509_22728} {RNA1310_14435.2} {RNA815_3120.1}
65. MligTC455_46967 1847 38.48 Mlig455_020253

Neo: -

Age: logFC(26M/2M)=0.172

 ACY1 0.958 - - - 0.958 - - Mlig455_020253 {REF} {Length: 2074} {TRANSSPLICED} {Pfam: Peptidase family M20/M25/M40 [PF01546.30, score=123.2]; Peptidase dimerisation domain [PF07687.16, score=51.4]; Peptidase family M28 [PF04389.19, score=27.9]} {Human: ENSG00000243989, ACY1, aminoacylase 1, [RH, Score=448, Expect=2e-156]; ENSG00000114786, ABHD14A-ACY1, ABHD14A-ACY1 readthrough, [RH, Score=442, Expect=1e-151]} {Mouse: ENSMUSG00000023262, Acy1, aminoacylase 1, [RH, Score=447, Expect=5e-156]} {Dmel: FBgn0039049, CG6726, [RH, Score=415, Expect=8e-144]} {Celegans: WBGene00007507, C10C5.3, Aminoacylase, [RH, Score=356, Expect=8e-121]} {Smed: dd_Smed_v6_1519_0_1, dd_Smed_v6_1519_0_1, [RH, Score=421, Expect=3e-146]} {RNA1509_6989} {RNA1310_10470.1, RNA1509_6989} {RNA1509_6989, RNA815_7022}
66. MligTC455_21905 681 14.18 Mlig455_016692, Mlig455_062345

Neo: Germline

Age: logFC(26M/2M)=0.410

Region-enriched R4: 2.760/0.00010

 0.957 - - - - 0.957 -

Mlig455_016692 {REF} {Length: 3207} {RNA1509_11497} {RNA1310_2097} {RNA815_6620}

Mlig455_062345 {REF} {Length: 877} {NoTransDecoderORF} {RNA1509_17998} {RNA1310_44069} {RNA815_10763.1}
67. MligTC455_50581 3916 81.58 Mlig455_019171

Neo: -

Age: Up-Down-Up

Region-enriched R4: 2.408/0.00005
Region-enriched R5: 1.476/0.00324

 0.956 - - - 0.956 - - Mlig455_019171 {REF} {Length: 2159} {Pfam: Taurine catabolism dioxygenase TauD, TfdA family [PF02668.18, score=96.2]} {RNA1509_11587, RNA1509_23506, RNA1509_26544, RNA1509_59770} {RNA1310_16045, RNA1509_11587, RNA1509_23506, RNA1509_26544, RNA1509_59770} {RNA1509_11587, RNA1509_23506, RNA1509_26544, RNA1509_59770, RNA815_6083.1}
68. MligTC455_33819 253 5.27 Mlig455_067196

Neo: -

Age: logFC(26M/2M)=0.525

Region-enriched R3: 2.609/0.00258

 SLC5A8 0.955 - - - - - 0.955 Mlig455_067196 {REF} {Length: 3149} {Pfam: Sodium:solute symporter family [PF00474.19, score=114.2]} {Human: ENSG00000262217, SLC5A8, solute carrier family 5 member 8, [Score=392, Expect=2e-127]; ENSG00000256870, SLC5A8, solute carrier family 5 member 8, [Score=392, Expect=2e-127]} {Mouse: ENSMUSG00000020062, Slc5a8, solute carrier family 5 (iodide transporter), member 8, [Score=397, Expect=2e-129]} {Dmel: FBgn0034494, CG10444, [Score=333, Expect=2e-105]} {Celegans: WBGene00014092, ZK822.5, [Score=212, Expect=4e-60]} {Smed: dd_Smed_v6_14173_0_1, dd_Smed_v6_14173_0_1, [Score=315, Expect=6e-99]} {RNA1509_3724, RNA1509_48113, RNA1509_52485} {RNA1310_1047.1, RNA1509_48113, RNA1509_52485} {RNA1509_48113, RNA1509_52485, RNA815_10363}

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