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Results for MligTC455_32445

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_32445 285 5.93 Mlig455_041727, Mlig455_042282

Neo: -

Age: -

ANK2

Mlig455_041727 {REF} {Length: 4931} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=276.7]; Ankyrin repeats (many copies) [PF13637.8, score=238.3]; Ankyrin repeat [PF00023.32, score=223.0]; Ankyrin repeats (many copies) [PF13857.8, score=214.9]; Ankyrin repeat [PF13606.8, score=201.4]; Ion transport protein [PF00520.33, score=46.6]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=211, Expect=1e-54]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=290, Expect=2e-80]} {Dmel: FBgn0011747, Ank, Ankyrin, [Score=210, Expect=2e-54]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=489, Expect=7e-151]} {Smed: dd_Smed_v6_6201_0_2, dd_Smed_v6_6201_0_2, [RH, Score=745, Expect=0.0]} {RNA1509_18945} {RNA1310_1506.1, RNA1509_18945} {RNA1509_18945, RNA815_450.1}

Mlig455_042282 {REF} {Length: 4940} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=273.8]; Ankyrin repeats (many copies) [PF13637.8, score=232.4]; Ankyrin repeat [PF00023.32, score=218.4]; Ankyrin repeats (many copies) [PF13857.8, score=210.6]; Ankyrin repeat [PF13606.8, score=197.5]; Ion transport protein [PF00520.33, score=46.6]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=214, Expect=2e-55]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=204, Expect=1e-52]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=201, Expect=2e-51]} {Dmel: FBgn0011747, Ank, Ankyrin, [Score=205, Expect=6e-53]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=487, Expect=5e-150]} {Smed: dd_Smed_v6_6201_0_2, dd_Smed_v6_6201_0_2, [RH, Score=736, Expect=0.0]} {RNA1509_18945} {RNA1310_1506.1} {RNA815_8298}

Cumulative graph for MligTC455_32445

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 2.314 3.009 0.17192 0.79728
RegionR2 1.506 3.009 0.03871 0.22843
RegionR3 -0.989 3.009 0.13183 0.62341
RegionR4 -0.628 3.009 0.47299 0.80077
RegionR5 -1.43 3.009 0.02810 0.12374
RegionR6 -2.923 3.009 0.00050 0.02437
RegionR7 0.564 3.009 0.47722 1.00000
RegionR8 1.588 3.009 0.07728 0.52970

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -7.644 3.009 0.08421 0.78241
RegenerationR2 0.413 3.009 0.43715 0.83866
RegenerationR3 -0.199 3.009 0.78070 0.97581
RegenerationR4 -0.121 3.009 0.89641 1.00000
RegenerationR5 -0.192 3.009 0.80296 0.98914
RegenerationR6 1.218 3.009 0.21816 0.56227
RegenerationBL -3.138 3.009 0.02420 0.17091
RegenerationTP -1.637 3.009 0.06992 0.42446


Genes with expression patterns similar to MligTC455_32445

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_32445 285 5.93 Mlig455_041727, Mlig455_042282

Neo: -

Age: -

ANK2 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_041727 {REF} {Length: 4931} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=276.7]; Ankyrin repeats (many copies) [PF13637.8, score=238.3]; Ankyrin repeat [PF00023.32, score=223.0]; Ankyrin repeats (many copies) [PF13857.8, score=214.9]; Ankyrin repeat [PF13606.8, score=201.4]; Ion transport protein [PF00520.33, score=46.6]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=211, Expect=1e-54]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=290, Expect=2e-80]} {Dmel: FBgn0011747, Ank, Ankyrin, [Score=210, Expect=2e-54]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=489, Expect=7e-151]} {Smed: dd_Smed_v6_6201_0_2, dd_Smed_v6_6201_0_2, [RH, Score=745, Expect=0.0]} {RNA1509_18945} {RNA1310_1506.1, RNA1509_18945} {RNA1509_18945, RNA815_450.1}

Mlig455_042282 {REF} {Length: 4940} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=273.8]; Ankyrin repeats (many copies) [PF13637.8, score=232.4]; Ankyrin repeat [PF00023.32, score=218.4]; Ankyrin repeats (many copies) [PF13857.8, score=210.6]; Ankyrin repeat [PF13606.8, score=197.5]; Ion transport protein [PF00520.33, score=46.6]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=214, Expect=2e-55]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=204, Expect=1e-52]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=201, Expect=2e-51]} {Dmel: FBgn0011747, Ank, Ankyrin, [Score=205, Expect=6e-53]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=487, Expect=5e-150]} {Smed: dd_Smed_v6_6201_0_2, dd_Smed_v6_6201_0_2, [RH, Score=736, Expect=0.0]} {RNA1509_18945} {RNA1310_1506.1} {RNA815_8298}
2. MligTC455_29929 164 3.41 Mlig455_030237, Mlig455_068015

Neo: -

Age: -

Region-enriched R2: 4.901/0.00350

SIX6 4.671 0.854 - 0.994 0.950 0.919 0.954

Mlig455_030237 {REF} {Length: 2545} {Pfam: Transcriptional regulator, SIX1, N-terminal SD domain [PF16878.7, score=152.1]; Homeodomain [PF00046.31, score=46.4]; Homeobox KN domain [PF05920.13, score=40.1]} {Human: ENSG00000184302, SIX6, SIX homeobox 6, [RH, Score=327, Expect=1e-109]; ENSG00000138083, SIX3, SIX homeobox 3, [RH, Score=325, Expect=8e-108]} {Mouse: ENSMUSG00000038805, Six3, sine oculis-related homeobox 3, [RH, Score=325, Expect=6e-108]; ENSMUSG00000021099, Six6, sine oculis-related homeobox 6, [RH, Score=323, Expect=2e-108]} {Dmel: FBgn0025360, Optix, [RH, Score=291, Expect=9e-93]} {Celegans: WBGene00000453, ceh-32, Homeobox protein ceh-32, [RH, Score=237, Expect=2e-72]} {Smed: dd_Smed_v6_11975_0_1, dd_Smed_v6_11975_0_1, [RH, Score=360, Expect=2e-119]} {RNA1509_39396} {RNA1310_25182.2} {RNA815_23127}

Mlig455_068015 {REF} {Length: 2713} {Pfam: Transcriptional regulator, SIX1, N-terminal SD domain [PF16878.7, score=152.2]; Homeodomain [PF00046.31, score=46.4]; Homeobox KN domain [PF05920.13, score=40.1]} {Human: ENSG00000184302, SIX6, SIX homeobox 6, [RH, Score=327, Expect=1e-109]; ENSG00000138083, SIX3, SIX homeobox 3, [RH, Score=325, Expect=7e-108]} {Mouse: ENSMUSG00000038805, Six3, sine oculis-related homeobox 3, [RH, Score=325, Expect=5e-108]; ENSMUSG00000021099, Six6, sine oculis-related homeobox 6, [RH, Score=323, Expect=2e-108]} {Dmel: FBgn0025360, Optix, [RH, Score=291, Expect=1e-92]} {Celegans: WBGene00000453, ceh-32, Homeobox protein ceh-32, [RH, Score=237, Expect=1e-72]} {Smed: dd_Smed_v6_11975_0_1, dd_Smed_v6_11975_0_1, [RH, Score=360, Expect=1e-119]} {RNA1509_39396} {RNA1310_25182.2} {RNA815_23127}
3. MligTC455_47080 362 7.54 Mlig455_037356

Neo: -

Age: -

Region-enriched R2: 2.691/0.00566

SSUH2 4.611 0.950 - 0.923 0.781 0.997 0.960 Mlig455_037356 {REF} {Length: 1984} {Pfam: DnaJ central domain [PF00684.21, score=20.9]} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=189, Expect=3e-56]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=156, Expect=5e-44]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=90.9, Expect=7e-20]} {RNA1509_29510} {RNA1310_15488, RNA1509_29510} {RNA1509_29510, RNA815_5650}
4. MligTC455_16813 75 1.56 Mlig455_049094

Neo: -

Age: -

NMUR2 4.466 0.862 - 0.878 0.868 0.970 0.888 Mlig455_049094 {REF} {Length: 1759} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=148.5]; Serpentine type 7TM GPCR chemoreceptor Srv [PF10323.11, score=34.9]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=25.8]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=21.2]} {Human: ENSG00000132911, NMUR2, neuromedin U receptor 2, [RH, Score=161, Expect=3e-44]} {Mouse: ENSMUSG00000037393, Nmur2, neuromedin U receptor 2, [RH, Score=176, Expect=6e-50]} {Dmel: FBgn0038140, PK2-R1, Pyrokinin 2 receptor 1, [RH, Score=213, Expect=6e-62]} {Celegans: WBGene00016747, nmur-1, NMUR (NeuroMedin U Receptor) homolog; Neuromedin U receptor, [RH, Score=177, Expect=2e-50]} {Smed: dd_Smed_v6_17801_0_1, dd_Smed_v6_17801_0_1, [Score=159, Expect=5e-44]} {RNA1310_33884} {RNA815_14436}
5. MligTC455_53844 1403 29.24 Mlig455_051626

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.540

4.363 0.804 0.729 - 0.893 0.979 0.958 Mlig455_051626 {REF} {Length: 1671} {RNA1509_15580} {RNA1310_24090} {RNA815_10676.2}
6. MligTC455_51051 233 4.85 Mlig455_046293

Neo: -

Age: -

4.356 0.774 - 0.729 0.959 0.918 0.976 Mlig455_046293 {REF} {Length: 1585} {RNA1310_32253}
7. MligTC455_53843 1448 30.17 Mlig455_048664

Neo: -

Age: logFC(26M/2M)=0.488

4.348 0.787 0.765 - 0.883 0.941 0.972 Mlig455_048664 {REF} {Length: 1660} {RNA1509_15580} {RNA1310_24090, RNA1509_15580} {RNA1509_15580, RNA815_10676.2}
8. MligTC455_52874 382 7.96 Mlig455_026014, Mlig455_070442

Neo: -

Age: -

CDH23 4.331 - 0.741 0.952 0.876 0.780 0.982

Mlig455_026014 {REF} {Length: 10931} {TRANSSPLICED} {Pfam: Cadherin domain [PF00028.19, score=362.8]; Cadherin-like [PF16184.7, score=40.0]; Cadherin-like [PF08266.14, score=32.1]} {Human: ENSG00000107736, CDH23, cadherin related 23, [Score=327, Expect=4e-90]} {Mouse: ENSMUSG00000012819, Cdh23, cadherin 23 (otocadherin), [Score=327, Expect=2e-90]} {Dmel: FBgn0038247, Cad88C, Cadherin 88C, [Score=404, Expect=8e-116]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=211, Expect=1e-54]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [Score=498, Expect=9e-149]} {RNA1509_48951} {RNA1310_475.1} {RNA815_321.1}

Mlig455_070442 {REF} {Length: 10801} {TRANSSPLICED} {Pfam: Cadherin domain [PF00028.19, score=364.1]; Cadherin-like [PF16184.7, score=39.7]; Cadherin-like [PF08266.14, score=30.9]} {Human: ENSG00000107736, CDH23, cadherin related 23, [Score=323, Expect=4e-89]} {Mouse: ENSMUSG00000012819, Cdh23, cadherin 23 (otocadherin), [Score=326, Expect=4e-90]} {Dmel: FBgn0038247, Cad88C, Cadherin 88C, [Score=404, Expect=8e-116]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=211, Expect=1e-54]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [Score=495, Expect=1e-147]} {RNA1509_44393, RNA1509_48951} {RNA1310_475.1, RNA1509_44393} {RNA1509_44393, RNA815_321.1}
9. MligTC455_42188 714 14.88 Mlig455_004983

Neo: -

Age: -

4.33 0.811 - 0.963 0.919 0.738 0.899 Mlig455_004983 {REF} {Length: 958} {RNA1509_36666, RNA1509_48333} {RNA1310_81420, RNA1509_36666, RNA1509_48333} {RNA1509_36666, RNA1509_48333, RNA815_25950}
10. MligTC455_27692 1230 25.62 Mlig455_041598

Neo: -

Age: logFC(26M/2M)=-0.459

Region-enriched R7: 1.679/0.00325
Region-enriched R8: 1.607/0.03580
Region-enriched R2: 1.508/0.02284

TUBA1A 4.319 - 0.834 0.745 0.836 0.977 0.927 Mlig455_041598 {REF} {Length: 2325} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=229.7]; Tubulin C-terminal domain [PF03953.19, score=175.5]; Tubulin domain [PF14881.8, score=18.9]} {Human: ENSG00000167552, TUBA1A, tubulin alpha 1a, [RH, Score=926, Expect=0.0]; ENSG00000123416, TUBA1B, tubulin alpha 1b, [RH, Score=923, Expect=0.0]; ENSG00000167553, TUBA1C, tubulin alpha 1c, [RH, Score=887, Expect=0.0]} {Mouse: ENSMUSG00000072235, Tuba1a, tubulin, alpha 1A, [RH, Score=926, Expect=0.0]; ENSMUSG00000023004, Tuba1b, tubulin, alpha 1B, [RH, Score=923, Expect=0.0]} {Dmel: FBgn0003884, alphaTub84B, alpha-Tubulin at 84B, [RH, Score=917, Expect=0.0]} {Celegans: WBGene00003175, mec-12, Tubulin alpha-3 chain Detyrosinated tubulin alpha-3 chain, [RH, Score=850, Expect=0.0]} {Smed: dd_Smed_v6_38_0_1, dd_Smed_v6_38_0_1, [RH, Score=924, Expect=0.0]} {RNA1509_21352, RNA1509_42319, RNA1509_9718} {RNA1310_10339.1, RNA1509_21352, RNA1509_42319} {RNA1509_21352, RNA1509_42319, RNA815_1715.1}
11. MligTC455_40654 676 14.08 Mlig455_056785

Neo: -

Age: logFC(26M/2M)=-0.402

CCDC63 4.303 0.821 - 0.790 0.768 0.973 0.951 Mlig455_056785 {REF} {Length: 2093} {TRANSSPLICED} {Pfam: Initiation control protein YabA [PF06156.15, score=20.5]} {Human: ENSG00000173093, CCDC63, coiled-coil domain containing 63, [RH, Score=190, Expect=9e-53]} {Mouse: ENSMUSG00000043036, Ccdc63, coiled-coil domain containing 63, [RH, Score=179, Expect=7e-49]} {Dmel: FBgn0038452, CG14905, [RH, Score=168, Expect=6e-46]} {Smed: dd_Smed_v6_4191_0_1, dd_Smed_v6_4191_0_1, [RH, Score=442, Expect=7e-150]} {RNA1509_17628} {RNA1310_12386, RNA1509_17628} {RNA1509_17628, RNA815_7054}
12. MligTC455_19266 1038 21.61 Mlig455_004528, Mlig455_028530

Neo: -

Age: -

Region-specific R2: 2.706

Region-enriched R2: 1.766/0.00005

NCALD 4.189 0.787 - 0.705 0.847 0.874 0.976

Mlig455_004528 {REF} {Length: 3958} {tRNA: Val(CAC),pseudo, score=38.6} {Pfam: EF-hand domain pair [PF13499.8, score=74.4]; EF hand [PF00036.34, score=71.3]; EF-hand domain [PF13405.8, score=66.3]; EF hand [PF13202.8, score=62.7]; EF-hand domain pair [PF13833.8, score=50.8]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=22.1]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=19.3]} {Human: ENSG00000104490, NCALD, neurocalcin delta, [Score=194, Expect=4e-63]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=191, Expect=1e-61]; ENSG00000121905, HPCA, hippocalcin, [Score=185, Expect=1e-59]} {Mouse: ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=194, Expect=2e-63]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=191, Expect=8e-62]; ENSMUSG00000028785, Hpca, hippocalcin, [Score=185, Expect=1e-59]} {Dmel: FBgn0036926, CG7646, [RH, Score=221, Expect=6e-74]} {Celegans: WBGene00003564, ncs-2, Neuronal calcium sensor 2, [Score=238, Expect=6e-81]} {Smed: dd_Smed_v6_5266_0_1, dd_Smed_v6_5266_0_1, [RH, Score=359, Expect=8e-129]} {RNA1509_14564} {RNA1310_18405, RNA1509_14564} {RNA1509_14564, RNA815_10180.1}

Mlig455_028530 {REF} {Length: 3453} {tRNA: Val(CAC),pseudo, score=38.6} {Pfam: EF-hand domain pair [PF13499.8, score=74.4]; EF hand [PF00036.34, score=71.3]; EF-hand domain [PF13405.8, score=66.3]; EF hand [PF13202.8, score=62.7]; EF-hand domain pair [PF13833.8, score=50.8]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=22.1]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=19.3]} {Human: ENSG00000104490, NCALD, neurocalcin delta, [Score=194, Expect=4e-63]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=191, Expect=1e-61]; ENSG00000121905, HPCA, hippocalcin, [Score=185, Expect=1e-59]} {Mouse: ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=194, Expect=2e-63]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=191, Expect=8e-62]; ENSMUSG00000028785, Hpca, hippocalcin, [Score=185, Expect=1e-59]} {Dmel: FBgn0036926, CG7646, [RH, Score=221, Expect=6e-74]} {Celegans: WBGene00003564, ncs-2, Neuronal calcium sensor 2, [Score=238, Expect=6e-81]} {Smed: dd_Smed_v6_5266_0_1, dd_Smed_v6_5266_0_1, [RH, Score=359, Expect=8e-129]} {RNA1509_13995, RNA1509_14564, RNA1509_30926} {RNA1310_18405, RNA1509_13995, RNA1509_30926} {RNA1509_13995, RNA1509_30926, RNA815_10180.1}
13. MligTC455_47806 2724 56.76 Mlig455_033677

Neo: -

Age: -

Region-specific R2: 3.773

Region-enriched R2: 2.504/0.00005

4.023 0.708 - 0.766 0.739 0.955 0.855 Mlig455_033677 {REF} {Length: 1836} {RNA1509_1605, RNA1509_16422, RNA1509_33244, RNA1509_46504} {RNA1310_30659.1, RNA1509_1605, RNA1509_16422, RNA1509_33244, RNA1509_46504} {RNA1509_1605, RNA1509_16422, RNA1509_33244, RNA1509_46504, RNA815_13807}
14. MligTC455_16416 290 6.04 Mlig455_000468

Neo: -

Age: -

Region-enriched R2: 2.225/0.04782

ROR1 3.771 0.901 - - 0.942 0.970 0.958 Mlig455_000468 {REF} {Length: 2686} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=208.1]; Protein kinase domain [PF00069.27, score=77.3]; Kringle domain [PF00051.20, score=19.4]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [Score=300, Expect=1e-89]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [Score=295, Expect=2e-87]; ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [Score=281, Expect=2e-82]} {Dmel: FBgn0010407, Ror, [Score=259, Expect=2e-76]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=217, Expect=2e-60]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [Score=328, Expect=1e-100]} {RNA1509_35395} {RNA1310_13558} {RNA815_27446}
15. MligTC455_41324 401 8.35 Mlig455_024997

Neo: -

Age: Up-Down-Down

CCDC151 3.768 - - 0.931 0.903 0.972 0.962 Mlig455_024997 {REF} {Length: 2376} {TRANSSPLICED} {Human: ENSG00000198003, CCDC151, coiled-coil domain containing 151, [Score=251, Expect=5e-75]} {Mouse: ENSMUSG00000039632, Ccdc151, coiled-coil domain containing 151, [Score=261, Expect=4e-79]} {Dmel: FBgn0036219, CCDC151, Coiled-coil domain containing protein 151, [Score=111, Expect=2e-25]} {Smed: dd_Smed_v6_4526_0_1, dd_Smed_v6_4526_0_1, [Score=463, Expect=3e-158]} {RNA1509_18758} {RNA1310_9513.1, RNA1509_18758} {RNA1509_18758, RNA815_13766}
16. MligTC455_16415 197 4.1 Mlig455_000401

Neo: -

Age: -

Region-enriched R2: 4.276/0.00982

ROR1 3.763 0.901 - - 0.934 0.978 0.950 Mlig455_000401 {REF} {Length: 3780} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=233.3]; Protein kinase domain [PF00069.27, score=85.9]; Immunoglobulin I-set domain [PF07679.18, score=49.4]; Immunoglobulin domain [PF13927.8, score=46.6]; Immunoglobulin domain [PF00047.27, score=31.9]; Immunoglobulin domain [PF13895.8, score=30.0]; Fz domain [PF01392.24, score=27.6]; Kringle domain [PF00051.20, score=22.3]; Immunoglobulin V-set domain [PF07686.19, score=19.5]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [RH, Score=390, Expect=1e-119]; ENSG00000169071, ROR2, receptor tyrosine kinase like orphan receptor 2, [RH, Score=379, Expect=1e-115]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [RH, Score=386, Expect=1e-118]; ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [RH, Score=377, Expect=4e-115]} {Dmel: FBgn0010407, Ror, [Score=286, Expect=3e-84]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=285, Expect=4e-82]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [RH, Score=439, Expect=2e-139]} {RNA1509_35395} {RNA1310_13558, RNA1509_35395} {RNA1509_35395, RNA815_27446}
17. MligTC455_54338 49 1.02 Mlig455_056485

Neo: -

Age: Up-Down-Down

PKDREJ 3.749 0.877 - - 0.958 0.943 0.971 Mlig455_056485 {REF} {Length: 11174} {Pfam: Polycystin cation channel [PF08016.14, score=290.0]; REJ domain [PF02010.17, score=90.7]; PLAT/LH2 domain [PF01477.25, score=67.3]; PKD domain [PF00801.22, score=47.7]; Ion transport protein [PF00520.33, score=40.1]; PKD domain [PF18911.2, score=29.8]; GPCR proteolysis site, GPS, motif [PF01825.23, score=27.4]; WSC domain [PF01822.21, score=27.0]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=280, Expect=1e-74]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=307, Expect=8e-83]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=151, Expect=3e-36]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [RH, Score=302, Expect=1e-81]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [RH, Score=1844, Expect=0.0]} {RNA1509_16432} {RNA1310_1236} {RNA815_2411}
18. MligTC455_39481 461 9.6 Mlig455_056703, Mlig455_060318

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.222

ANGPTL1 3.748 0.935 - - 0.956 0.905 0.952

Mlig455_056703 {REF} {Length: 1114} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=79.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=89.4, Expect=1e-19]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=85.1, Expect=3e-18]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=91.3, Expect=2e-20]} {Dmel: FBgn0033312, CG8642, [Score=82.4, Expect=1e-17]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=76.3, Expect=1e-15]} {RNA1310_31288} {RNA815_20497.1}

Mlig455_060318 {REF} {Length: 1175} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=112.7]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=106, Expect=2e-25]; ENSG00000171819, ANGPTL7, angiopoietin like 7, [Score=105, Expect=6e-26]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=109, Expect=1e-26]} {Dmel: FBgn0034160, CG5550, [Score=96.3, Expect=2e-23]} {Celegans: WBGene00016769, C49C8.5, [Score=47.0, Expect=9e-06]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=88.2, Expect=2e-19]} {RNA1310_31288} {RNA815_20497.1}
19. MligTC455_16908 161 3.35 Mlig455_046916

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.397

Region-enriched R2: 2.938/0.02849

SLC17A6 3.718 0.921 - 0.865 - 0.959 0.973 Mlig455_046916 {REF} {Length: 3198} {Pfam: Major Facilitator Superfamily [PF07690.18, score=172.0]; Uncharacterised MFS-type transporter YbfB [PF06779.16, score=19.6]} {Human: ENSG00000091664, SLC17A6, solute carrier family 17 member 6, [RH, Score=548, Expect=0.0]; ENSG00000179520, SLC17A8, solute carrier family 17 member 8, [RH, Score=542, Expect=0.0]; ENSG00000104888, SLC17A7, solute carrier family 17 member 7, [RH, Score=536, Expect=0.0]} {Mouse: ENSMUSG00000019935, Slc17a8, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8, [RH, Score=551, Expect=0.0]; ENSMUSG00000030500, Slc17a6, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6, [RH, Score=547, Expect=0.0]; ENSMUSG00000070570, Slc17a7, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, [RH, Score=543, Expect=0.0]} {Dmel: FBgn0031424, VGlut, Vesicular glutamate transporter, [Score=482, Expect=6e-163]} {Celegans: WBGene00001135, eat-4, Probable vesicular glutamate transporter eat-4, [RH, Score=479, Expect=7e-163]} {Smed: dd_Smed_v6_10192_0_1, dd_Smed_v6_10192_0_1, [RH, Score=591, Expect=0.0]} {RNA1509_38152} {RNA1310_23072, RNA1509_38152} {RNA1509_38152, RNA815_14894}
20. MligTC455_19908 490 10.21 Mlig455_047266, Mlig455_047318, Mlig455_069346

Neo: -

Age: logFC(26M/2M)=0.566

3.717 0.852 - - 0.968 0.942 0.955

Mlig455_047266 {REF} {Length: 1728} {Pfam: Glycine rich protein [PF12810.9, score=49.4]} {RNA1509_28009} {RNA1310_17226} {RNA815_32720}

Mlig455_047318 {REF} {Length: 2268} {Pfam: Glycine rich protein [PF12810.9, score=36.7]} {RNA1509_28009} {RNA1310_17226, RNA1509_28009} {RNA1509_28009, RNA815_32720}

Mlig455_069346 {REF} {Length: 1953} {Pfam: Glycine rich protein [PF12810.9, score=31.6]} {RNA1509_28009} {RNA1310_17226} {RNA815_32720}
21. MligTC455_40289 93 1.94 Mlig455_017727, Mlig455_056175

Neo: -

Age: -

BMP1, CUBN 3.715 0.897 - - 0.954 0.973 0.891

Mlig455_017727 {REF} {Length: 1202} {Pfam: CUB domain [PF00431.22, score=55.3]} {Human: ENSG00000107611, CUBN, cubilin, [Score=54.7, Expect=4e-08]; ENSG00000168487, BMP1, bone morphogenetic protein 1, [Score=52.0, Expect=3e-07]} {Mouse: ENSMUSG00000026726, Cubn, cubilin (intrinsic factor-cobalamin receptor), [Score=51.6, Expect=3e-07]; ENSMUSG00000022098, Bmp1, bone morphogenetic protein 1, [Score=49.7, Expect=1e-06]} {Dmel: FBgn0003719, tld, tolloid, [Score=51.2, Expect=3e-07]} {Smed: dd_Smed_v6_69474_0_1, dd_Smed_v6_69474_0_1, [Score=47.4, Expect=2e-07]} {RNA1310_48745} {RNA815_23305}

Mlig455_056175 {REF} {Length: 2747} {Pfam: CUB domain [PF00431.22, score=62.6]} {Human: ENSG00000168487, BMP1, bone morphogenetic protein 1, [Score=52.8, Expect=2e-07]; ENSG00000107611, CUBN, cubilin, [Score=51.6, Expect=4e-07]} {Mouse: ENSMUSG00000022098, Bmp1, bone morphogenetic protein 1, [Score=51.6, Expect=3e-07]; ENSMUSG00000026726, Cubn, cubilin (intrinsic factor-cobalamin receptor), [Score=49.7, Expect=1e-06]} {Dmel: FBgn0003719, tld, tolloid, [Score=51.2, Expect=3e-07]} {Smed: dd_Smed_v6_69474_0_1, dd_Smed_v6_69474_0_1, [Score=47.0, Expect=3e-07]} {RNA1310_48745} {RNA815_23305}
22. MligTC455_31853 516 10.74 Mlig455_014495, Mlig455_014514, Mlig455_054434

Neo: -

Age: -

3.705 0.829 - - 0.941 0.988 0.947

Mlig455_014495 {REF} {Length: 3100} {RNA1509_20117} {RNA1310_5956.1, RNA1509_20117} {RNA1509_20117, RNA815_18508}

Mlig455_014514 {REF} {Length: 3051} {Smed: dd_Smed_v6_3795_0_2, dd_Smed_v6_3795_0_2, [RH, Score=89.7, Expect=2e-19]} {RNA1509_20117} {RNA1310_5956.1} {RNA815_18508}

Mlig455_054434 {REF} {Length: 4026} {Pfam: Late embryogenesis abundant protein [PF03242.15, score=21.0]} {Smed: dd_Smed_v6_3795_0_2, dd_Smed_v6_3795_0_2, [RH, Score=89.4, Expect=2e-20]} {RNA1509_20117} {RNA1310_8165} {RNA815_23492}
23. MligTC455_35019 168 3.49 Mlig455_046994

Neo: -

Age: -

ASIC4 3.7 0.890 - 0.966 - 0.851 0.993 Mlig455_046994 {REF} {Length: 4001} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=101.4]} {Human: ENSG00000072182, ASIC4, acid sensing ion channel subunit family member 4, [Score=76.3, Expect=1e-13]} {Mouse: ENSMUSG00000033007, Asic4, acid-sensing (proton-gated) ion channel family member 4, [Score=76.3, Expect=8e-14]; ENSMUSG00000023017, Asic1, acid-sensing (proton-gated) ion channel 1, [Score=72.8, Expect=8e-13]} {Smed: dd_Smed_v6_15233_0_1, dd_Smed_v6_15233_0_1, [RH, Score=103, Expect=1e-22]} {RNA1509_33816} {RNA1310_3176, RNA1509_33816} {RNA1509_33816, RNA815_12439}
24. MligTC455_29408 45 0.94 Mlig455_038322

Neo: -

Age: -

Region-enriched R2: 8.586/0.00762

MB 3.675 0.825 - - 0.925 0.965 0.960 Mlig455_038322 {REF} {Length: 2059} {Pfam: Globin [PF00042.24, score=57.8]} {Human: ENSG00000198125, MB, myoglobin, [RH, Score=47.8, Expect=5e-07]} {Mouse: ENSMUSG00000018893, Mb, myoglobin, [RH, Score=45.4, Expect=2e-06]} {Celegans: WBGene00008996, glb-14, GLoBin related, [Score=51.6, Expect=4e-08]} {Smed: dd_Smed_v6_15997_0_1, dd_Smed_v6_15997_0_1, [RH, Score=63.5, Expect=1e-12]} {RNA1509_48898} {RNA1310_47695} {RNA815_7096.1}
25. MligTC455_33832 112 2.34 Mlig455_029411

Neo: -

Age: Up-Down-Down

Region-enriched R2: 5.300/0.00016
Region-enriched R8: 4.136/0.03070

GLRA3 3.671 0.968 - - 0.797 0.995 0.911 Mlig455_029411 {REF} {Length: 3686} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=149.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=84.5]} {Human: ENSG00000145451, GLRA3, glycine receptor alpha 3, [Score=257, Expect=5e-80]; ENSG00000145888, GLRA1, glycine receptor alpha 1, [Score=253, Expect=3e-78]; ENSG00000101958, GLRA2, glycine receptor alpha 2, [Score=250, Expect=4e-77]} {Mouse: ENSMUSG00000038257, Glra3, glycine receptor, alpha 3 subunit, [Score=251, Expect=2e-77]; ENSMUSG00000018589, Glra2, glycine receptor, alpha 2 subunit, [Score=249, Expect=5e-77]; ENSMUSG00000000263, Glra1, glycine receptor, alpha 1 subunit, [Score=248, Expect=2e-76]; ENSMUSG00000018595, Glra4, glycine receptor, alpha 4 subunit, [Score=243, Expect=1e-74]} {Dmel: FBgn0024963, GluClalpha, [Score=253, Expect=2e-78]} {Celegans: WBGene00000233, avr-15, GluClalpha2B protein, [Score=259, Expect=7e-81]} {Smed: dd_Smed_v6_11342_0_1, dd_Smed_v6_11342_0_1, [RH, Score=480, Expect=1e-167]} {RNA1509_35986} {RNA1310_35528} {RNA815_35433}
26. MligTC455_31163 72 1.51 Mlig455_045625

Neo: -

Age: Up-Down-Down

3.668 0.850 - - 0.884 0.976 0.958 Mlig455_045625 {REF} {Length: 1957} {RNA1509_21720} {RNA1310_14760, RNA1509_21720} {RNA1509_21720, RNA815_24583}
27. MligTC455_35529 117 2.43 Mlig455_020107, Mlig455_069888

Neo: -

Age: -

3.663 0.913 - - 0.912 0.860 0.978

Mlig455_020107 {REF} {Length: 3566} {RNA1509_53783} {RNA1310_29335.1} {RNA815_9084.1}

Mlig455_069888 {REF} {Length: 2216} {RNA1509_44264} {RNA1310_56703} {RNA815_9084.1}
28. MligTC455_49307 122 2.55 Mlig455_055230

Neo: -

Age: -

Region-enriched R2: 4.447/0.04819

ZAN 3.658 0.910 - - 0.884 0.988 0.876 Mlig455_055230 {REF} {Length: 2947} {Pfam: Glycine rich protein [PF12810.9, score=28.6]} {Human: ENSG00000146839, ZAN, zonadhesin (gene/pseudogene), [Score=79.7, Expect=1e-14]} {Mouse: ENSMUSG00000079173, Zan, zonadhesin, [Score=80.1, Expect=7e-15]} {RNA1310_18897} {RNA815_40026}
29. MligTC455_32446 142 2.95 Mlig455_042069

Neo: -

Age: Up-Down-Down

TRPA1 3.656 0.829 - 0.896 - 0.960 0.971 Mlig455_042069 {REF} {Length: 6835} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=191.2]; Ankyrin repeats (many copies) [PF13637.8, score=164.6]; Ankyrin repeats (many copies) [PF13857.8, score=152.4]; Ankyrin repeat [PF13606.8, score=136.2]; Ankyrin repeat [PF00023.32, score=129.7]; Ion transport protein [PF00520.33, score=47.4]} {Human: ENSG00000104321, TRPA1, transient receptor potential cation channel subfamily A member 1, [Score=176, Expect=1e-44]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=286, Expect=4e-81]} {Dmel: FBgn0035934, TrpA1, Transient receptor potential cation channel A1, [Score=173, Expect=6e-44]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=450, Expect=2e-140]} {Smed: dd_Smed_v6_6201_0_1, dd_Smed_v6_6201_0_1, [Score=627, Expect=0.0]} {RNA1509_32186} {RNA1310_1780} {RNA815_450.1}
30. MligTC455_52570 71 1.49 Mlig455_066071

Neo: -

Age: Up-Down-Up

3.654 0.765 - - 0.945 0.990 0.954 Mlig455_066071 {REF} {Length: 2575} {Pfam: Hemingway/CFA97 [PF13879.8, score=54.6]; Annexin [PF00191.22, score=26.1]} {Mouse: ENSMUSG00000090336, Cfap97d2, CFAP97 domain containing 2, [Score=46.6, Expect=3e-06]} {Smed: dd_Smed_v6_2676_0_1, dd_Smed_v6_2676_0_1, [Score=70.1, Expect=2e-13]} {RNA1310_29320.1} {RNA815_54680}
31. MligTC455_43741 196 4.08 Mlig455_018088

Neo: -

Age: Down-Up-Down

PTBP1 3.652 0.898 - - 0.946 0.834 0.974 Mlig455_018088 {REF} {Length: 2775} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF13893.8, score=116.9]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=52.7]; Occluded RNA-recognition motif [PF16842.7, score=26.8]} {Human: ENSG00000011304, PTBP1, polypyrimidine tract binding protein 1, [Score=258, Expect=8e-80]; ENSG00000117569, PTBP2, polypyrimidine tract binding protein 2, [Score=258, Expect=1e-80]; ENSG00000119314, PTBP3, polypyrimidine tract binding protein 3, [Score=248, Expect=1e-76]} {Mouse: ENSMUSG00000028134, Ptbp2, polypyrimidine tract binding protein 2, [Score=258, Expect=7e-81]; ENSMUSG00000006498, Ptbp1, polypyrimidine tract binding protein 1, [Score=251, Expect=1e-78]; ENSMUSG00000028382, Ptbp3, polypyrimidine tract binding protein 3, [Score=248, Expect=1e-77]} {Dmel: FBgn0011224, heph, hephaestus, [Score=249, Expect=7e-78]} {Celegans: WBGene00004207, ptb-1, PTB (HnRNP) homolog; Putative RNA-binding protein PTB-1b, [Score=234, Expect=1e-72]} {Smed: dd_Smed_v6_1868_0_1, dd_Smed_v6_1868_0_1, [Score=214, Expect=4e-64]} {RNA1509_36451} {RNA1310_3345} {RNA815_23519}
32. MligTC455_18564 196 4.08 Mlig455_063527

Neo: -

Age: -

Region-enriched R2: 2.416/0.01839

PRKG2 3.643 - - 0.978 0.732 0.956 0.977 Mlig455_063527 {REF} {Length: 2971} {Pfam: Protein kinase domain [PF00069.27, score=212.4]; Cyclic nucleotide-binding domain [PF00027.31, score=135.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=103.7]; Kinase-like [PF14531.8, score=24.8]} {Human: ENSG00000138669, PRKG2, protein kinase cGMP-dependent 2, [RH, Score=653, Expect=0.0]} {Mouse: ENSMUSG00000029334, Prkg2, protein kinase, cGMP-dependent, type II, [RH, Score=651, Expect=0.0]} {Dmel: FBgn0000442, Pkg21D, Protein kinase, cGMP-dependent at 21D, [RH, Score=662, Expect=0.0]} {Celegans: WBGene00001173, egl-4, cGMP-dependent protein kinase egl-4, [Score=655, Expect=0.0]} {Smed: dd_Smed_v6_6967_0_1, dd_Smed_v6_6967_0_1, [RH, Score=645, Expect=0.0]} {RNA1509_38353} {RNA1310_8466, RNA1509_38353} {RNA1509_38353, RNA815_6313}
33. MligTC455_36985 363 7.57 Mlig455_046905

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.516

SCNN1A 3.631 - - 0.910 0.920 0.841 0.960 Mlig455_046905 {REF} {Length: 2490} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=171.1]} {Human: ENSG00000111319, SCNN1A, sodium channel epithelial 1 alpha subunit, [Score=68.6, Expect=2e-11]} {Mouse: ENSMUSG00000028008, Asic5, acid-sensing (proton-gated) ion channel family member 5, [Score=67.0, Expect=3e-11]} {Celegans: WBGene00006748, unc-8, Degenerin unc-8, [Score=58.2, Expect=1e-08]} {Smed: dd_Smed_v6_29341_0_1, dd_Smed_v6_29341_0_1, [Score=100, Expect=2e-22]} {RNA1509_33610} {RNA1310_13314.1, RNA1509_33610} {RNA1509_33610, RNA815_4277}
34. MligTC455_50914 714 14.87 Mlig455_005873

Neo: -

Age: -

Region-enriched R2: 2.125/0.01399

DNHD1 3.629 0.844 - - 0.960 0.943 0.882 Mlig455_005873 {REF} {Length: 14506} {Pfam: Dynein heavy chain, N-terminal region 2 [PF08393.15, score=207.8]; Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=114.3]; P-loop containing dynein motor region D4 [PF12780.9, score=60.3]; Microtubule-binding stalk of dynein motor [PF12777.9, score=54.5]; P-loop containing dynein motor region [PF12775.9, score=46.5]; Dynein heavy chain C-terminal domain [PF18199.3, score=42.8]; Dynein heavy chain AAA lid domain [PF17852.3, score=38.9]; AAA domain [PF13401.8, score=22.7]; Dynein heavy chain AAA lid domain [PF18198.3, score=22.0]; Protein of unknown function (DUF815) [PF05673.15, score=20.3]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=19.7]} {Human: ENSG00000179532, DNHD1, dynein heavy chain domain 1, [Score=159, Expect=1e-37]} {Mouse: ENSMUSG00000030882, Dnhd1, dynein heavy chain domain 1, [Score=177, Expect=3e-43]} {Dmel: FBgn0013811, Dhc62B, Dynein heavy chain at 62B, [Score=114, Expect=4e-24]} {Celegans: WBGene00000485, che-3, Cytoplasmic dynein 2 heavy chain 1, [Score=82.0, Expect=1e-14]} {Smed: dd_Smed_v6_8984_0_1, dd_Smed_v6_8984_0_1, [Score=331, Expect=5e-90]} {RNA1509_32900} {RNA1310_31} {RNA815_1203}
35. MligTC455_38682 102 2.12 Mlig455_039641

Neo: -

Age: -

Region-enriched R2: 6.138/0.02363

SLC18A3 3.627 0.866 - - 0.874 0.978 0.909 Mlig455_039641 {REF} {Length: 3925} {Pfam: Major Facilitator Superfamily [PF07690.18, score=147.1]; Sugar (and other) transporter [PF00083.26, score=29.0]; LacY proton/sugar symporter [PF01306.21, score=20.2]} {Human: ENSG00000187714, SLC18A3, solute carrier family 18 member A3, [RH, Score=469, Expect=9e-161]} {Mouse: ENSMUSG00000100241, Slc18a3, solute carrier family 18 (vesicular monoamine), member 3, [RH, Score=469, Expect=1e-160]} {Dmel: FBgn0270928, VAChT, Vesicular acetylcholine transporter, [RH, Score=513, Expect=2e-177]} {Celegans: WBGene00006756, unc-17, Vesicular acetylcholine transporter unc-17, [RH, Score=486, Expect=2e-167]} {Smed: dd_Smed_v6_11630_0_1, dd_Smed_v6_11630_0_1, [RH, Score=563, Expect=0.0]} {RNA1310_28397} {RNA815_32284.1}
36. MligTC455_40878 355 7.39 Mlig455_014130

Neo: -

Age: -

3.619 0.852 - - 0.829 0.953 0.985 Mlig455_014130 {REF} {Length: 1465} {RNA1509_7458} {RNA1310_36212} {RNA815_1610.1}
37. MligTC455_46880 44 0.91 Mlig455_046271

Neo: -

Age: -

IAH1 3.612 0.765 - - 0.933 0.938 0.976 Mlig455_046271 {REF} {Length: 1061} {Pfam: GDSL-like Lipase/Acylhydrolase family [PF13472.8, score=75.8]; GDSL-like Lipase/Acylhydrolase [PF00657.24, score=32.0]} {Human: ENSG00000134330, IAH1, isoamyl acetate hydrolyzing esterase 1 (putative), [Score=138, Expect=2e-39]} {Mouse: ENSMUSG00000062054, Iah1, isoamyl acetate-hydrolyzing esterase 1 homolog, [Score=121, Expect=4e-33]} {Smed: dd_Smed_v6_6241_0_1, dd_Smed_v6_6241_0_1, [Score=111, Expect=8e-30]} {RNA1310_130726}
38. MligTC455_50532 259 5.4 Mlig455_019987

Neo: -

Age: Down-Up-Down

NEFH 3.612 0.804 - - 0.882 0.980 0.946 Mlig455_019987 {REF} {Length: 4055} {Human: ENSG00000100285, NEFH, neurofilament heavy, [Score=65.5, Expect=3e-10]} {RNA1509_41200, RNA1509_57173} {RNA1310_3614.2, RNA1509_41200, RNA1509_57173} {RNA1509_41200, RNA1509_57173, RNA815_5328}
39. MligTC455_24536 120 2.5 Mlig455_028895

Neo: -

Age: Up-Down-Down

TRPA1 3.61 0.756 - - 0.968 0.926 0.960 Mlig455_028895 {REF} {Length: 4399} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=276.9]; Ankyrin repeats (many copies) [PF13637.8, score=235.5]; Ankyrin repeats (many copies) [PF13857.8, score=187.3]; Ankyrin repeat [PF00023.32, score=185.3]; Ankyrin repeat [PF13606.8, score=184.2]; Ion transport protein [PF00520.33, score=31.3]} {Human: ENSG00000104321, TRPA1, transient receptor potential cation channel subfamily A member 1, [Score=295, Expect=6e-83]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=277, Expect=4e-77]} {Dmel: FBgn0035934, TrpA1, Transient receptor potential cation channel A1, [Score=305, Expect=2e-86]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=276, Expect=1e-76]} {Smed: dd_Smed_v6_20683_0_1, dd_Smed_v6_20683_0_1, [RH, Score=551, Expect=2e-178]} {RNA1509_56559} {RNA1310_3837.1} {RNA815_4441}
40. MligTC455_53842 1222 25.46 Mlig455_023890

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.345

Region-enriched R2: 1.546/0.01667

3.598 0.757 - - 0.937 0.938 0.966 Mlig455_023890 {REF} {Length: 1336} {RNA1509_15580} {RNA1310_22487.1} {RNA815_10676.1}
41. MligTC455_45487 110 2.3 Mlig455_004129, Mlig455_060457

Neo: -

Age: -

3.595 0.765 - 0.921 - 0.953 0.956

Mlig455_004129 {REF} {Length: 1131} {Pfam: PAN domain [PF00024.28, score=18.8]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=64.3, Expect=2e-12]} {RNA1310_37660} {RNA815_17816.1}

Mlig455_060457 {REF} {Length: 1507} {Pfam: PAN domain [PF00024.28, score=19.5]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=64.3, Expect=2e-12]} {RNA1509_54623} {RNA1310_33480} {RNA815_17816.1}
42. MligTC455_29915 50 1.04 Mlig455_027934

Neo: -

Age: Down-Up-Up

Region-enriched R2: 6.881/0.04464

ANGPTL1 3.586 0.882 - - 0.896 0.852 0.956 Mlig455_027934 {REF} {Length: 2265} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=43.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=48.9, Expect=9e-06]} {Dmel: FBgn0031804, CG9500, [Score=53.1, Expect=9e-08]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=49.7, Expect=1e-06]} {RNA1509_53291} {RNA1310_38229.1} {RNA815_10579.1}
43. MligTC455_46067 548 11.42 Mlig455_054518, Mlig455_055436, Mlig455_055448

Neo: -

Age: Up-Down-Down

Region-enriched R4: 4.305/0.04262

GRIK3, GRIK4 3.584 - - 0.932 0.742 0.937 0.973

Mlig455_054518 {REF} {Length: 4725} {Pfam: Ligand-gated ion channel [PF00060.28, score=109.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=91.0]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=81.2]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=222, Expect=5e-60]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=222, Expect=6e-60]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=218, Expect=3e-58]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=216, Expect=3e-58]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=215, Expect=1e-57]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=213, Expect=9e-57]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=213, Expect=9e-57]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=224, Expect=2e-60]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=224, Expect=9e-61]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=220, Expect=2e-59]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=216, Expect=2e-58]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=215, Expect=1e-57]} {Dmel: FBgn0031634, Ir25a, Ionotropic receptor 25a, [RH, Score=296, Expect=6e-86]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [RH, Score=312, Expect=2e-94]} {Smed: dd_Smed_v6_16476_0_1, dd_Smed_v6_16476_0_1, [RH, Score=674, Expect=0.0]} {RNA1509_14215, RNA1509_40992} {RNA1310_5620.1, RNA1509_14215, RNA1509_40992} {RNA1509_14215, RNA1509_40992, RNA815_1965}

Mlig455_055436 {REF} {Length: 4732} {Pfam: Ligand-gated ion channel [PF00060.28, score=109.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=90.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=81.1]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=219, Expect=6e-59]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=218, Expect=7e-59]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=218, Expect=7e-59]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=216, Expect=3e-58]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=216, Expect=9e-58]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=211, Expect=2e-56]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=209, Expect=1e-55]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=226, Expect=3e-61]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=221, Expect=1e-59]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=216, Expect=2e-58]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=216, Expect=2e-58]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=216, Expect=3e-58]} {Dmel: FBgn0031634, Ir25a, Ionotropic receptor 25a, [RH, Score=297, Expect=2e-86]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [RH, Score=313, Expect=2e-94]} {Smed: dd_Smed_v6_16476_0_1, dd_Smed_v6_16476_0_1, [RH, Score=674, Expect=0.0]} {RNA1509_40992} {RNA1310_5620.1} {RNA815_1965}

Mlig455_055448 {REF} {Length: 4726} {Pfam: Ligand-gated ion channel [PF00060.28, score=109.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=90.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=81.1]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=219, Expect=9e-59]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=218, Expect=9e-59]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=218, Expect=8e-59]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=217, Expect=2e-58]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=216, Expect=7e-58]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=213, Expect=6e-57]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=209, Expect=1e-55]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=225, Expect=4e-61]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=221, Expect=1e-59]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=217, Expect=9e-59]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=216, Expect=5e-58]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=216, Expect=3e-58]} {Dmel: FBgn0031634, Ir25a, Ionotropic receptor 25a, [RH, Score=297, Expect=2e-86]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [RH, Score=313, Expect=2e-94]} {Smed: dd_Smed_v6_16476_0_1, dd_Smed_v6_16476_0_1, [RH, Score=674, Expect=0.0]} {RNA1509_32892, RNA1509_40992} {RNA1310_5620.1, RNA1509_32892} {RNA1509_32892, RNA815_1965}
44. MligTC455_13963 31 0.64 Mlig455_052027

Neo: -

Age: Down-Up-Down

3.581 0.765 - - 0.880 0.982 0.954 Mlig455_052027 {REF} {Length: 1717} {RNA1509_48973} {RNA1310_34931} {RNA815_59614}
45. MligTC455_30159 107 2.22 Mlig455_008465, Mlig455_009916

Neo: -

Age: Up-Down-Down

Region-enriched R2: 4.961/0.00498

TCF7L1 3.579 0.768 - 0.972 - 0.924 0.915

Mlig455_008465 {REF} {Length: 2454} {Pfam: HMG (high mobility group) box [PF00505.21, score=81.3]; HMG-box domain [PF09011.12, score=34.6]} {Human: ENSG00000152284, TCF7L1, transcription factor 7 like 1, [RH, Score=161, Expect=7e-43]; ENSG00000138795, LEF1, lymphoid enhancer binding factor 1, [RH, Score=159, Expect=3e-43]; ENSG00000081059, TCF7, transcription factor 7, [RH, Score=156, Expect=8e-42]} {Mouse: ENSMUSG00000055799, Tcf7l1, transcription factor 7 like 1 (T cell specific, HMG box), [RH, Score=161, Expect=4e-43]; ENSMUSG00000027985, Lef1, lymphoid enhancer binding factor 1, [RH, Score=159, Expect=4e-44]; ENSMUSG00000000782, Tcf7, transcription factor 7, T cell specific, [RH, Score=155, Expect=6e-43]} {Dmel: FBgn0085432, pan, pangolin, [RH, Score=157, Expect=4e-41]} {Celegans: WBGene00004077, pop-1, [Score=108, Expect=2e-25]} {Smed: dd_Smed_v6_34144_0_1, dd_Smed_v6_34144_0_1, [RH, Score=166, Expect=2e-48]} {RNA1310_11181} {RNA815_36690}

Mlig455_009916 {REF} {Length: 2137} {Pfam: HMG (high mobility group) box [PF00505.21, score=81.4]; HMG-box domain [PF09011.12, score=34.7]} {Human: ENSG00000152284, TCF7L1, transcription factor 7 like 1, [RH, Score=161, Expect=4e-43]; ENSG00000138795, LEF1, lymphoid enhancer binding factor 1, [RH, Score=159, Expect=2e-43]; ENSG00000081059, TCF7, transcription factor 7, [RH, Score=157, Expect=5e-42]} {Mouse: ENSMUSG00000055799, Tcf7l1, transcription factor 7 like 1 (T cell specific, HMG box), [RH, Score=162, Expect=2e-43]; ENSMUSG00000027985, Lef1, lymphoid enhancer binding factor 1, [RH, Score=159, Expect=3e-44]; ENSMUSG00000000782, Tcf7, transcription factor 7, T cell specific, [RH, Score=155, Expect=4e-43]} {Dmel: FBgn0085432, pan, pangolin, [RH, Score=157, Expect=3e-41]} {Celegans: WBGene00004077, pop-1, [Score=108, Expect=2e-25]} {Smed: dd_Smed_v6_34144_0_1, dd_Smed_v6_34144_0_1, [RH, Score=166, Expect=1e-48]} {RNA1310_11181} {RNA815_36690}
46. MligTC455_42037 1931 40.23 Mlig455_063391

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.444

Region-specific R2: 2.479

Region-enriched R2: 1.442/0.00136

3.578 0.784 - - 0.892 0.937 0.965 Mlig455_063391 {REF} {Length: 1482} {RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236} {RNA1310_24553, RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236} {RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236, RNA815_11766}
47. MligTC455_18787 963 20.06 Mlig455_014022

Neo: -

Age: -

Region-enriched R2: 1.334/0.03482

STRC 3.575 0.791 - - 0.883 0.930 0.971 Mlig455_014022 {REF} {Length: 5754} {Human: ENSG00000242866, STRC, stereocilin, [RH, Score=76.3, Expect=4e-13]} {Mouse: ENSMUSG00000033498, Strc, stereocilin, [RH, Score=80.9, Expect=1e-14]} {RNA1509_4378} {RNA1310_1493.1, RNA1509_4378} {RNA1509_4378, RNA815_804}
48. MligTC455_46395 870 18.13 Mlig455_069471

Neo: -

Age: logFC(26M/2M)=0.458

PKD2 3.574 - - 0.717 0.970 0.925 0.962 Mlig455_069471 {REF} {Length: 3122} {TRANSSPLICED} {Pfam: Polycystin cation channel [PF08016.14, score=487.8]; Ion transport protein [PF00520.33, score=93.3]; EF hand [PF00036.34, score=32.7]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=21.3]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=753, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=750, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=323, Expect=1e-96]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=387, Expect=8e-123]} {Smed: dd_Smed_v6_13327_0_1, dd_Smed_v6_13327_0_1, [RH, Score=769, Expect=0.0]} {RNA1509_13522} {RNA1310_21296.2} {RNA815_3158.1}
49. MligTC455_15330 373 7.77 Mlig455_020220

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.289

3.569 - - 0.899 0.803 0.900 0.967 Mlig455_020220 {REF} {Length: 2115} {Pfam: Fas apoptotic inhibitory molecule (FAIM1) [PF06905.15, score=41.4]} {Smed: dd_Smed_v6_4798_0_1, dd_Smed_v6_4798_0_1, [RH, Score=82.0, Expect=3e-20]} {RNA1509_28885, RNA1509_54654} {RNA1310_42962.2, RNA1509_28885, RNA1509_54654} {RNA1509_28885, RNA1509_54654, RNA815_23071}
50. MligTC455_40290 58 1.21 Mlig455_058728

Neo: -

Age: -

Region-enriched R2: 4.464/0.00807
Region-enriched R7: 3.833/0.03206

3.559 0.938 - - 0.775 0.977 0.869 Mlig455_058728 {REF} {Length: 1351} {Pfam: CUB domain [PF00431.22, score=48.4]} {RNA1310_48745} {RNA815_23305}
51. MligTC455_50053 284 5.92 Mlig455_030746

Neo: -

Age: -

Region-enriched R2: 1.768/0.02980

STOM 3.559 0.847 0.863 - - 0.876 0.973 Mlig455_030746 {REF} {Length: 2635} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=58.5]} {Human: ENSG00000148175, STOM, stomatin, [Score=257, Expect=7e-85]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [Score=253, Expect=2e-83]} {Dmel: FBgn0260657, CG42540, [Score=262, Expect=9e-86]} {Celegans: WBGene00003166, mec-2, Mechanosensory protein 2, [Score=275, Expect=6e-91]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [Score=304, Expect=4e-104]} {RNA1509_53478} {RNA1310_8094.2} {RNA815_8739}
52. MligTC455_31164 572 11.91 Mlig455_029609, Mlig455_045673

Neo: -

Age: -

3.555 0.735 - - 0.908 0.944 0.968

Mlig455_029609 {REF} {Length: 746} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=39.4]} {Smed: dd_Smed_v6_22533_0_1, dd_Smed_v6_22533_0_1, [Score=48.5, Expect=1e-06]} {RNA1310_96354} {RNA815_44390}

Mlig455_045673 {REF} {Length: 2025} {RNA1509_21720} {RNA1310_14760} {RNA815_24583}
53. MligTC455_27025 706 14.7 Mlig455_054786, Mlig455_054878

Neo: -

Age: -

Region-enriched R2: 3.519/0.00005

CD82 3.55 0.881 - - 0.779 0.918 0.972

Mlig455_054786 {REF} {Length: 2796} {Pfam: Tetraspanin family [PF00335.22, score=142.8]} {Human: ENSG00000085117, CD82, CD82 molecule, [RH, Score=86.3, Expect=4e-19]} {Mouse: ENSMUSG00000027215, Cd82, CD82 antigen, [RH, Score=94.0, Expect=3e-22]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [Score=98.6, Expect=6e-24]} {Celegans: WBGene00006632, tsp-6, Tetraspanin, [Score=74.7, Expect=1e-15]} {Smed: dd_Smed_v6_13639_0_1, dd_Smed_v6_13639_0_1, [RH, Score=160, Expect=2e-47]} {RNA1509_20389, RNA1509_43644, RNA1509_56428} {RNA1310_8032.1, RNA1509_20389, RNA1509_43644, RNA1509_56428} {RNA1509_20389, RNA1509_43644, RNA1509_56428, RNA815_3380.1}

Mlig455_054878 {REF} {Length: 4398} {Pfam: Tetraspanin family [PF00335.22, score=143.7]} {Human: ENSG00000085117, CD82, CD82 molecule, [RH, Score=84.7, Expect=2e-18]} {Mouse: ENSMUSG00000027215, Cd82, CD82 antigen, [RH, Score=92.4, Expect=2e-21]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [Score=99.8, Expect=4e-24]} {Celegans: WBGene00006643, tsp-17, TetraSPanin family, [RH, Score=73.2, Expect=1e-14]} {Smed: dd_Smed_v6_13639_0_1, dd_Smed_v6_13639_0_1, [RH, Score=160, Expect=2e-47]} {RNA1509_56428} {RNA1310_8032.2} {RNA815_3380.1}
54. MligTC455_35895 102 2.12 Mlig455_063971

Neo: -

Age: -

RYK 3.547 0.846 - - 0.867 0.871 0.963 Mlig455_063971 {REF} {Length: 3496} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=209.4]; WIF domain [PF02019.20, score=109.7]; Protein kinase domain [PF00069.27, score=79.1]} {Human: ENSG00000163785, RYK, receptor-like tyrosine kinase, [Score=202, Expect=1e-55]} {Mouse: ENSMUSG00000032547, Ryk, receptor-like tyrosine kinase, [RH, Score=202, Expect=2e-55]} {Dmel: FBgn0015380, drl, derailed, [RH, Score=239, Expect=4e-69]} {Celegans: WBGene00003007, lin-18, Inactive tyrosine-protein kinase RYK, [Score=179, Expect=6e-48]} {Smed: dd_Smed_v6_12594_0_2, dd_Smed_v6_12594_0_2, [Score=201, Expect=3e-55]} {RNA1509_58811} {RNA1310_6671.2} {RNA815_41921}
55. MligTC455_32644 41 0.86 Mlig455_043770, Mlig455_043786

Neo: -

Age: -

Region-enriched R2: 6.705/0.00336

3.544 0.755 - - 0.947 0.886 0.956

Mlig455_043770 {REF} {Length: 1011} {Pfam: PAN domain [PF00024.28, score=19.3]} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=60.8, Expect=3e-11]} {RNA1509_35604} {RNA1310_57814} {RNA815_29718}

Mlig455_043786 {REF} {Length: 1348} {Pfam: PAN domain [PF00024.28, score=19.3]} {RNA1509_35604} {RNA1310_34182} {RNA815_29718}
56. MligTC455_48022 1337 27.86 Mlig455_045267, Mlig455_069186

Neo: -

Age: -

Region-enriched R2: 2.130/0.00146

3.536 0.790 - - 0.918 0.966 0.862

Mlig455_045267 {REF} {Length: 3628} {Pfam: Ankyrin repeats (many copies) [PF13857.8, score=29.5]; Ankyrin repeats (many copies) [PF13637.8, score=28.4]; Ankyrin repeats (3 copies) [PF12796.9, score=28.3]; Ankyrin repeat [PF13606.8, score=23.5]} {Celegans: WBGene00009375, F34D10.6, [Score=57.0, Expect=6e-08]} {Smed: dd_Smed_v6_5594_0_3, dd_Smed_v6_5594_0_3, [Score=58.5, Expect=1e-08]} {RNA1509_17412, RNA1509_32079} {RNA1310_5952, RNA1509_17412, RNA1509_32079} {RNA1509_17412, RNA1509_32079, RNA815_2323}

Mlig455_069186 {REF} {Length: 3598} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=30.4]; Ankyrin repeats (3 copies) [PF12796.9, score=30.1]; Ankyrin repeats (many copies) [PF13857.8, score=29.5]; Ankyrin repeat [PF13606.8, score=24.1]} {Celegans: WBGene00009375, F34D10.6, [Score=56.6, Expect=6e-08]} {Smed: dd_Smed_v6_5594_0_4, dd_Smed_v6_5594_0_4, [Score=59.3, Expect=7e-09]} {RNA1509_52963} {RNA1310_5952, RNA1509_52963} {RNA1509_52963, RNA815_2323}
57. MligTC455_51199 206 4.29 Mlig455_044015

Neo: -

Age: Down-Up-Down

ARX 3.531 0.827 0.823 - 0.972 0.909 - Mlig455_044015 {REF} {Length: 1926} {Pfam: Homeodomain [PF00046.31, score=85.3]} {Human: ENSG00000004848, ARX, aristaless related homeobox, [Score=116, Expect=8e-30]} {Mouse: ENSMUSG00000035277, Arx, aristaless related homeobox, [Score=115, Expect=1e-29]} {Dmel: FBgn0008636, hbn, homeobrain, [Score=128, Expect=5e-35]} {Celegans: WBGene00000433, ceh-8, Homeobox protein ceh-8, [RH, Score=103, Expect=6e-27]} {Smed: dd_Smed_v6_16955_0_1, dd_Smed_v6_16955_0_1, [Score=105, Expect=9e-27]} {RNA1509_46102} {RNA1310_37906, RNA1509_46102}
58. MligTC455_49491 136 2.83 Mlig455_054796

Neo: -

Age: -

Region-enriched R2: 7.065/0.00003

3.528 0.920 - - 0.834 0.819 0.955 Mlig455_054796 {REF} {Length: 1567} {RNA1509_22234} {RNA1310_23973} {RNA815_10832}
59. MligTC455_43979 188 3.92 Mlig455_000082, Mlig455_063749

Neo: -

Age: -

GHSR 3.515 0.765 - - 0.915 0.882 0.953

Mlig455_000082 {REF} {Length: 1342} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=53.1]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=18.2]} {Human: ENSG00000121853, GHSR, growth hormone secretagogue receptor, [Score=52.0, Expect=7e-07]} {Mouse: ENSMUSG00000051136, Ghsr, growth hormone secretagogue receptor, [Score=50.4, Expect=2e-06]} {Celegans: WBGene00018798, gnrr-1, GoNadotropin-Releasing hormone Receptor (GnRHR) related, [Score=48.9, Expect=3e-06]} {Smed: dd_Smed_v6_60346_0_1, dd_Smed_v6_60346_0_1, [RH, Score=160, Expect=9e-47]} {RNA1310_30553}

Mlig455_063749 {REF} {Length: 1323} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=48.3]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=20.4]} {Smed: dd_Smed_v6_60346_0_1, dd_Smed_v6_60346_0_1, [RH, Score=157, Expect=1e-45]} {RNA1310_30553}
60. MligTC455_25073 1271 26.47 Mlig455_015905

Neo: -

Age: logFC(26M/2M)=-0.947

Region-specific R2: 3.291

Region-enriched R2: 2.110/0.00052

PI16 3.513 0.906 - 0.864 - 0.786 0.957 Mlig455_015905 {REF} {Length: 2189} {Pfam: Cysteine-rich secretory protein family [PF00188.28, score=71.8]} {Human: ENSG00000164530, PI16, peptidase inhibitor 16, [Score=111, Expect=1e-26]} {Mouse: ENSMUSG00000024011, Pi16, peptidase inhibitor 16, [RH, Score=115, Expect=7e-28]} {Dmel: FBgn0038126, CG8483, [Score=95.1, Expect=2e-21]} {Celegans: WBGene00011462, vap-2, Venom-Allergen-like Protein, [RH, Score=85.5, Expect=3e-18]} {Smed: dd_Smed_v6_2512_0_1, dd_Smed_v6_2512_0_1, [Score=140, Expect=2e-39]} {RNA1509_36129, RNA1509_46021, RNA1509_5027} {RNA1310_1356.1, RNA1509_36129, RNA1509_46021} {RNA1509_36129, RNA1509_46021, RNA815_4508}
61. MligTC455_48766 985 20.53 Mlig455_020052, Mlig455_022298

Neo: -

Age: logFC(26M/2M)=-0.287

ODF3 3.498 - - 0.816 0.885 0.834 0.963

Mlig455_020052 {REF} {Length: 1742} {TRANSSPLICED} {Pfam: Sperm-tail PG-rich repeat [PF07004.14, score=82.0]} {Human: ENSG00000177947, ODF3, outer dense fiber of sperm tails 3, [RH, Score=188, Expect=6e-59]} {Mouse: ENSMUSG00000025482, Odf3, outer dense fiber of sperm tails 3, [RH, Score=187, Expect=1e-58]} {Dmel: FBgn0032010, CG8086, [RH, Score=119, Expect=2e-32]} {Smed: dd_Smed_v6_2658_0_1, dd_Smed_v6_2658_0_1, [Score=304, Expect=4e-105]} {RNA1509_28289, RNA1509_56680} {RNA1310_15149, RNA1509_56680} {RNA1509_56680, RNA815_9422}

Mlig455_022298 {REF} {Length: 2031} {TRANSSPLICED} {Pfam: Sperm-tail PG-rich repeat [PF07004.14, score=82.0]} {Human: ENSG00000177947, ODF3, outer dense fiber of sperm tails 3, [RH, Score=188, Expect=6e-59]} {Mouse: ENSMUSG00000025482, Odf3, outer dense fiber of sperm tails 3, [RH, Score=187, Expect=1e-58]} {Dmel: FBgn0032010, CG8086, [RH, Score=119, Expect=2e-32]} {Smed: dd_Smed_v6_2658_0_1, dd_Smed_v6_2658_0_1, [Score=304, Expect=4e-105]} {RNA1509_28289, RNA1509_54276} {RNA1310_15149, RNA1509_28289, RNA1509_54276} {RNA1509_28289, RNA1509_54276, RNA815_9422}
62. MligTC455_19276 1694 35.28 Mlig455_057303

Neo: -

Age: Down-Down-Up

Region-specific R2: 5.711

Region-enriched R2: 6.117/0.00000
Region-enriched R3: 2.663/0.00058

3.496 0.766 - - 0.876 0.899 0.955 Mlig455_057303 {REF} {Length: 1196} {Pfam: TATA-binding related factor (TRF) of subunit 20 of Mediator complex [PF08612.13, score=80.6]} {Smed: dd_Smed_v6_9879_0_1, dd_Smed_v6_9879_0_1, [RH, Score=73.9, Expect=1e-15]} {RNA1509_58478} {RNA1310_35292} {RNA815_20171}
63. MligTC455_41382 65 1.35 Mlig455_022554

Neo: -

Age: -

Region-enriched R2: 5.596/0.01432

3.496 0.765 - 0.946 - 0.831 0.954 Mlig455_022554 {REF} {Length: 503} {Pfam: Pancreatic hormone peptide [PF00159.20, score=18.9]} {RNA1310_81495} {RNA815_42745}
64. MligTC455_51559 43 0.89 Mlig455_002923, Mlig455_002941

Neo: -

Age: -

Region-enriched R2: 6.806/0.01463

3.489 0.765 - - 0.924 0.844 0.956

Mlig455_002923 {REF} {Length: 1008} {RNA1310_77227} {RNA815_43894}

Mlig455_002941 {REF} {Length: 897} {RNA1310_88681} {RNA815_43894}
65. MligTC455_47538 50 1.03 Mlig455_025826

Neo: -

Age: -

Region-enriched R2: 5.073/0.01138
Region-enriched R3: 3.811/0.02847

CALM2 3.488 0.870 - - 0.897 0.771 0.950 Mlig455_025826 {REF} {Length: 1670} {Pfam: EF hand [PF00036.34, score=107.9]; EF-hand domain pair [PF13499.8, score=105.5]; EF hand [PF13202.8, score=83.6]; EF-hand domain pair [PF13833.8, score=83.3]; EF-hand domain [PF13405.8, score=75.8]; EF-hand domain [PF14658.8, score=35.5]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=29.8]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=27.8]; Dockerin type I domain [PF00404.20, score=20.3]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=93.2, Expect=3e-24]; ENSG00000198668, CALM1, calmodulin 1, [Score=93.2, Expect=3e-24]; ENSG00000160014, CALM3, calmodulin 3, [Score=93.2, Expect=3e-24]; ENSG00000178363, CALML3, calmodulin like 3, [Score=92.8, Expect=4e-24]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=99.8, Expect=5e-27]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=91.3, Expect=6e-24]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=90.9, Expect=9e-24]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=90.9, Expect=7e-24]} {RNA1509_52504} {RNA1310_7529} {RNA815_34450}
66. MligTC455_19278 4335 90.31 Mlig455_057304, Mlig455_070944

Neo: -

Age: logFC(26M/2M)=0.686

Region-specific R2: 5.590

Region-enriched R2: 5.465/0.00000
Region-enriched R3: 2.308/0.00629

CHRNA10 3.484 0.757 - - 0.874 0.898 0.955

Mlig455_057304 {REF} {Length: 1001} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=71.6]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=77.0, Expect=2e-16]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=75.9, Expect=4e-16]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=75.5, Expect=6e-16]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=73.9, Expect=2e-15]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=93.6, Expect=2e-22]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=100, Expect=5e-25]} {Smed: dd_Smed_v6_11955_0_1, dd_Smed_v6_11955_0_1, [Score=82.8, Expect=8e-19]} {RNA1509_23115} {RNA1310_34970} {RNA815_15305.1}

Mlig455_070944 {REF} {Length: 1060} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=88.2]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=95.9, Expect=6e-22]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=96.3, Expect=3e-22]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=94.7, Expect=1e-21]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=112, Expect=7e-28]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=118, Expect=4e-30]} {Smed: dd_Smed_v6_18184_0_1, dd_Smed_v6_18184_0_1, [Score=98.6, Expect=2e-23]} {RNA1509_23115, RNA1509_43907, RNA1509_9432} {RNA1310_34970, RNA1509_23115, RNA1509_43907, RNA1509_9432} {RNA1509_23115, RNA1509_43907, RNA1509_9432, RNA815_15305.1}
67. MligTC455_34369 112 2.34 Mlig455_015308, Mlig455_015354, Mlig455_036248, Mlig455_068737, Mlig455_070110

Neo: -

Age: Up-Down-Up

Region-enriched R2: 5.462/0.00546

3.481 0.826 - - 0.733 0.983 0.939

Mlig455_015308 {REF} {Length: 1459} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=63.9]} {RNA1310_34740} {RNA815_15663}

Mlig455_015354 {REF} {Length: 1446} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=66.3]; Sialidase, N-terminal domain [PF02973.18, score=18.5]} {RNA1310_34740} {RNA815_15663}

Mlig455_036248 {REF} {Length: 2111} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=120.9]; Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=28.5]; PAN domain [PF00024.28, score=19.9]} {RNA1509_45496} {RNA1310_2539.1} {RNA815_252.1}

Mlig455_068737 {REF} {Length: 1096} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=68.3]; Sialidase, N-terminal domain [PF02973.18, score=19.9]} {RNA1310_34740} {RNA815_37905}

Mlig455_070110 {REF} {Length: 1340} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=109.6]} {RNA1509_32599} {RNA1310_1659} {RNA815_252.1}
68. MligTC455_39096 110 2.29 Mlig455_019781, Mlig455_019803

Neo: -

Age: -

3.466 0.864 - - 0.915 0.733 0.954

Mlig455_019781 {REF} {Length: 1107} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=65.0]} {RNA1310_34740} {RNA815_15663}

Mlig455_019803 {REF} {Length: 1107} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=63.1]} {RNA1310_34740} {RNA815_15663}
69. MligTC455_17021 49 1.02 Mlig455_030263

Neo: -

Age: -

3.455 0.815 - - 0.890 0.776 0.974 Mlig455_030263 {REF} {Length: 566} {TRANSSPLICED} {Pfam: Galactosyltransferase [PF01762.23, score=23.7]} {Dmel: FBgn0000221, brn, brainiac, [Score=45.8, Expect=1e-06]} {RNA1310_35735} {RNA815_59866}
70. MligTC455_54282 74 1.54 Mlig455_020191

Neo: -

Age: -

3.445 0.748 - - 0.762 0.979 0.956 Mlig455_020191 {REF} {Length: 937} {RNA1509_48973} {RNA1310_40738.2} {RNA815_31898}
71. MligTC455_23621 323 6.72 Mlig455_039694, Mlig455_039749

Neo: -

Age: -

Region-enriched R2: 2.235/0.02499

3.437 0.867 - - 0.878 0.730 0.962

Mlig455_039694 {REF} {Length: 2054} {RNA1509_29694} {RNA1310_14789} {RNA815_12997}

Mlig455_039749 {REF} {Length: 1751} {RNA1509_29694} {RNA1310_14789, RNA1509_29694} {RNA1509_29694, RNA815_12997}
72. MligTC455_44186 185 3.85 Mlig455_052492

Neo: -

Age: -

3.425 0.765 - 0.954 0.925 0.781 - Mlig455_052492 {REF} {Length: 959} {Pfam: Lectin C-type domain [PF00059.23, score=33.2]} {RNA1509_20946} {RNA1310_41618} {RNA815_32434}
73. MligTC455_53504 217 4.51 Mlig455_037385

Neo: -

Age: -

Region-enriched R2: 3.142/0.00738

CSMD1 3.424 0.811 - - 0.727 0.904 0.982 Mlig455_037385 {REF} {Length: 2214} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=198.7]} {Human: ENSG00000183117, CSMD1, CUB and Sushi multiple domains 1, [Score=149, Expect=8e-37]} {Mouse: ENSMUSG00000028369, Svep1, sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1, [Score=136, Expect=7e-33]; ENSMUSG00000060924, Csmd1, CUB and Sushi multiple domains 1, [Score=134, Expect=5e-32]; ENSMUSG00000022311, Csmd3, CUB and Sushi multiple domains 3, [Score=133, Expect=9e-32]} {Dmel: FBgn0032797, Hasp, Hig-anchoring scaffold protein, [RH, Score=218, Expect=3e-60]} {Celegans: WBGene00002976, lev-9, [RH, Score=244, Expect=4e-72]} {Smed: dd_Smed_v6_13071_0_1, dd_Smed_v6_13071_0_1, [RH, Score=296, Expect=1e-91]} {RNA1509_55985} {RNA1310_12867.1, RNA1509_55985} {RNA1509_55985, RNA815_9157}
74. MligTC455_43326 39 0.8 Mlig455_057987

Neo: -

Age: -

3.423 0.807 - - 0.852 0.803 0.961 Mlig455_057987 {REF} {Length: 1058} {RNA1310_129308}
75. MligTC455_50915 531 11.06 Mlig455_028745

Neo: -

Age: Up-Down-Down

Region-enriched R2: 2.109/0.02468

DNHD1 3.417 0.734 - - 0.953 0.961 0.769 Mlig455_028745 {REF} {Length: 14999} {TRANSSPLICED} {Pfam: Dynein heavy chain, N-terminal region 2 [PF08393.15, score=214.3]; Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=113.4]; P-loop containing dynein motor region D4 [PF12780.9, score=60.1]; Microtubule-binding stalk of dynein motor [PF12777.9, score=55.6]; P-loop containing dynein motor region [PF12775.9, score=49.4]; Dynein heavy chain C-terminal domain [PF18199.3, score=44.7]; Dynein heavy chain AAA lid domain [PF17852.3, score=40.5]; AAA domain [PF13401.8, score=23.5]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=22.3]; Dynein heavy chain AAA lid domain [PF18198.3, score=22.0]; Protein of unknown function (DUF815) [PF05673.15, score=21.1]; AAA domain [PF13604.8, score=18.7]} {Human: ENSG00000179532, DNHD1, dynein heavy chain domain 1, [Score=157, Expect=4e-37]} {Mouse: ENSMUSG00000030882, Dnhd1, dynein heavy chain domain 1, [Score=249, Expect=8e-65]} {Dmel: FBgn0013811, Dhc62B, Dynein heavy chain at 62B, [Score=114, Expect=2e-24]} {Celegans: WBGene00000485, che-3, Cytoplasmic dynein 2 heavy chain 1, [Score=84.0, Expect=4e-15]} {Smed: dd_Smed_v6_8984_0_1, dd_Smed_v6_8984_0_1, [RH, Score=443, Expect=5e-124]} {RNA1509_1896} {RNA1310_31, RNA1509_1896} {RNA1509_1896, RNA815_1203}
76. MligTC455_39890 162 3.37 Mlig455_047281, Mlig455_047331, Mlig455_069333

Neo: -

Age: -

Region-enriched R2: 6.097/0.00148

PLSCR1 3.408 0.760 - - 0.913 0.776 0.959

Mlig455_047281 {REF} {Length: 1404} {Pfam: Scramblase [PF03803.17, score=248.1]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=225, Expect=4e-72]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=227, Expect=5e-73]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=222, Expect=3e-71]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=223, Expect=6e-73]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=194, Expect=2e-61]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [RH, Score=306, Expect=1e-104]} {RNA1310_29769} {RNA815_41335}

Mlig455_047331 {REF} {Length: 1395} {Pfam: Scramblase [PF03803.17, score=248.1]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=225, Expect=4e-72]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=227, Expect=5e-73]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=222, Expect=3e-71]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=223, Expect=6e-73]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=194, Expect=2e-61]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [RH, Score=306, Expect=1e-104]} {RNA1310_29769} {RNA815_41335}

Mlig455_069333 {REF} {Length: 1416} {Pfam: Scramblase [PF03803.17, score=248.7]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=226, Expect=1e-72]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=228, Expect=2e-73]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=223, Expect=1e-71]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=224, Expect=2e-73]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=194, Expect=4e-61]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [RH, Score=304, Expect=2e-103]} {RNA1310_29769} {RNA815_41335}
77. MligTC455_35773 89 1.86 Mlig455_064449, Mlig455_064456

Neo: -

Age: -

Region-enriched R2: 5.198/0.00725

NANP 3.4 0.882 - - 0.807 0.962 0.749

Mlig455_064449 {REF} {Length: 503} {NoTransDecoderORF} {RNA1310_53432.2}

Mlig455_064456 {REF} {Length: 3122} {Pfam: Haloacid dehalogenase-like hydrolase [PF13419.8, score=56.3]; haloacid dehalogenase-like hydrolase [PF00702.28, score=55.3]; HAD-hyrolase-like [PF13242.8, score=44.6]} {Human: ENSG00000170191, NANP, N-acetylneuraminic acid phosphatase, [RH, Score=47.4, Expect=8e-06]} {Mouse: ENSMUSG00000053916, Nanp, N-acetylneuraminic acid phosphatase, [RH, Score=48.5, Expect=2e-06]} {Celegans: WBGene00018465, F45E1.4, [RH, Score=147, Expect=4e-43]} {Smed: dd_Smed_v6_2813_0_3, dd_Smed_v6_2813_0_3, [Score=174, Expect=2e-50]} {RNA1310_59243} {RNA815_62364}
78. MligTC455_07624 777 16.19 Mlig455_062715

Neo: -

Age: Up-Down-Up

STOM 3.394 - - 0.959 0.841 0.834 0.760 Mlig455_062715 {REF} {Length: 3417} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=112.9]} {Human: ENSG00000148175, STOM, stomatin, [RH, Score=365, Expect=3e-126]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [RH, Score=362, Expect=2e-125]} {Dmel: FBgn0260657, CG42540, [RH, Score=384, Expect=9e-131]} {Celegans: WBGene00006064, sto-2, Stomatin-2, [RH, Score=393, Expect=2e-136]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [Score=379, Expect=3e-132]} {RNA1509_47159, RNA1509_9137} {RNA1310_11482.1, RNA1509_47159, RNA1509_9137} {RNA1509_47159, RNA1509_9137, RNA815_6842}
79. MligTC455_43509 1526 31.78 Mlig455_024779, Mlig455_066104, Mlig455_068669

Neo: -

Age: Down-Up-Up

ACSL1 3.377 0.778 - - 0.762 0.950 0.887

Mlig455_024779 {REF} {Length: 2596} {Pfam: AMP-binding enzyme [PF00501.30, score=343.5]; AMP-binding enzyme C-terminal domain [PF13193.8, score=23.4]} {Human: ENSG00000151726, ACSL1, acyl-CoA synthetase long chain family member 1, [Score=534, Expect=0.0]; ENSG00000164398, ACSL6, acyl-CoA synthetase long chain family member 6, [Score=518, Expect=1e-175]; ENSG00000197142, ACSL5, acyl-CoA synthetase long chain family member 5, [Score=514, Expect=2e-174]} {Mouse: ENSMUSG00000018796, Acsl1, acyl-CoA synthetase long-chain family member 1, [Score=515, Expect=9e-175]; ENSMUSG00000024981, Acsl5, acyl-CoA synthetase long-chain family member 5, [Score=513, Expect=6e-174]; ENSMUSG00000020333, Acsl6, acyl-CoA synthetase long-chain family member 6, [Score=509, Expect=3e-172]} {Dmel: FBgn0036821, CG3961, [RH, Score=552, Expect=0.0]} {Celegans: WBGene00013575, acs-5, Fatty Acid CoA Synthetase family, [Score=476, Expect=4e-160]} {Smed: dd_Smed_v6_2009_0_2, dd_Smed_v6_2009_0_2, [Score=427, Expect=5e-141]} {RNA1509_51374} {RNA1310_7356.1} {RNA815_5550.1}

Mlig455_066104 {REF} {Length: 2816} {Pfam: AMP-binding enzyme [PF00501.30, score=343.8]; AMP-binding enzyme C-terminal domain [PF13193.8, score=23.5]} {Human: ENSG00000151726, ACSL1, acyl-CoA synthetase long chain family member 1, [Score=531, Expect=1e-180]; ENSG00000197142, ACSL5, acyl-CoA synthetase long chain family member 5, [Score=516, Expect=3e-175]; ENSG00000164398, ACSL6, acyl-CoA synthetase long chain family member 6, [Score=513, Expect=1e-173]} {Mouse: ENSMUSG00000018796, Acsl1, acyl-CoA synthetase long-chain family member 1, [Score=512, Expect=2e-173]; ENSMUSG00000024981, Acsl5, acyl-CoA synthetase long-chain family member 5, [Score=511, Expect=4e-173]; ENSMUSG00000020333, Acsl6, acyl-CoA synthetase long-chain family member 6, [Score=506, Expect=5e-171]} {Dmel: FBgn0036821, CG3961, [RH, Score=551, Expect=0.0]} {Celegans: WBGene00013575, acs-5, Fatty Acid CoA Synthetase family, [Score=476, Expect=6e-160]} {Smed: dd_Smed_v6_2009_0_2, dd_Smed_v6_2009_0_2, [Score=424, Expect=7e-140]} {RNA1509_21029, RNA1509_51374} {RNA1310_7356.1, RNA1509_21029, RNA1509_51374} {RNA1509_21029, RNA1509_51374, RNA815_5550.1}

Mlig455_068669 {REF} {Length: 2627} {Pfam: AMP-binding enzyme [PF00501.30, score=343.5]; AMP-binding enzyme C-terminal domain [PF13193.8, score=23.4]} {Human: ENSG00000151726, ACSL1, acyl-CoA synthetase long chain family member 1, [Score=534, Expect=0.0]; ENSG00000164398, ACSL6, acyl-CoA synthetase long chain family member 6, [Score=518, Expect=1e-175]; ENSG00000197142, ACSL5, acyl-CoA synthetase long chain family member 5, [Score=514, Expect=2e-174]} {Mouse: ENSMUSG00000018796, Acsl1, acyl-CoA synthetase long-chain family member 1, [Score=515, Expect=9e-175]; ENSMUSG00000024981, Acsl5, acyl-CoA synthetase long-chain family member 5, [Score=513, Expect=6e-174]; ENSMUSG00000020333, Acsl6, acyl-CoA synthetase long-chain family member 6, [Score=509, Expect=3e-172]} {Dmel: FBgn0036821, CG3961, [RH, Score=552, Expect=0.0]} {Celegans: WBGene00013575, acs-5, Fatty Acid CoA Synthetase family, [Score=476, Expect=4e-160]} {Smed: dd_Smed_v6_2009_0_2, dd_Smed_v6_2009_0_2, [Score=427, Expect=5e-141]} {RNA1509_51374} {RNA1310_7356.1} {RNA815_5550.1}
80. MligTC455_28847 131 2.73 Mlig455_045073

Neo: -

Age: -

3.361 0.877 0.704 - 0.807 - 0.973 Mlig455_045073 {REF} {Length: 588} {RNA1509_57120} {RNA1310_63606.1} {RNA815_49827}
81. MligTC455_42579 1841 38.34 Mlig455_061617

Neo: -

Age: -

Region-enriched R7: 1.560/0.01513

Regeneration-downregulated BL: -2.445

Regeneration-depleted BL: -2.445

CAV2 3.36 0.764 0.749 - 0.893 - 0.954 Mlig455_061617 {REF} {Length: 4295} {Pfam: Caveolin [PF01146.19, score=121.3]} {Human: ENSG00000105971, CAV2, caveolin 2, [Score=87.4, Expect=2e-22]} {Mouse: ENSMUSG00000000058, Cav2, caveolin 2, [Score=90.1, Expect=1e-23]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [Score=73.2, Expect=1e-16]} {Smed: dd_Smed_v6_8555_0_1, dd_Smed_v6_8555_0_1, [Score=144, Expect=2e-45]} {RNA1509_24227} {RNA1310_41576, RNA1509_24227} {RNA1509_24227, RNA815_20166}
82. MligTC455_14903 1751 36.49 Mlig455_037514

Neo: -

Age: -

Region-enriched R8: 1.893/0.00470

3.35 - 0.707 - 0.906 0.775 0.962 Mlig455_037514 {REF} {Length: 2886} {Dmel: FBgn0034294, Muc55B, Mucin 55B, [Score=58.5, Expect=6e-09]} {Celegans: WBGene00008194, C49C3.4, [Score=51.2, Expect=1e-06]} {RNA1509_4337} {RNA1310_7259} {RNA815_206}
83. MligTC455_53414 331 6.9 Mlig455_053442

Neo: -

Age: -

Region-specific R2: 4.308

Region-enriched R2: 3.374/0.00040

RP1 3.341 0.716 - - 0.718 0.944 0.963 Mlig455_053442 {REF} {Length: 1156} {Pfam: PLAT/LH2 domain [PF01477.25, score=155.8]; Doublecortin [PF03607.19, score=103.5]; Embryo-specific protein 3, (ATS3) [PF06232.13, score=22.0]} {Human: ENSG00000104237, RP1, RP1, axonemal microtubule associated, [Score=473, Expect=5e-146]} {Mouse: ENSMUSG00000025900, Rp1, retinitis pigmentosa 1 (human), [Score=454, Expect=1e-136]} {Dmel: FBgn0261387, CG17528, [Score=56.6, Expect=1e-07]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [Score=75.5, Expect=2e-13]} {Smed: dd_Smed_v6_10315_0_2, dd_Smed_v6_10315_0_2, [Score=698, Expect=0.0]} {RNA1509_21828} {RNA1310_33070.1} {RNA815_13802.1}
84. MligTC455_53415 319 6.64 Mlig455_053444

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.862

Region-enriched R2: 4.179/0.00011

RP1 3.34 0.716 - - 0.720 0.943 0.961 Mlig455_053444 {REF} {Length: 4944} {Pfam: PLAT/LH2 domain [PF01477.25, score=155.3]; Doublecortin [PF03607.19, score=100.5]; Embryo-specific protein 3, (ATS3) [PF06232.13, score=22.5]; Fibroblast growth factor [PF00167.20, score=18.6]} {Human: ENSG00000104237, RP1, RP1, axonemal microtubule associated, [Score=471, Expect=6e-145]} {Mouse: ENSMUSG00000025900, Rp1, retinitis pigmentosa 1 (human), [Score=453, Expect=3e-136]} {Dmel: FBgn0261387, CG17528, [Score=56.6, Expect=1e-07]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [Score=75.9, Expect=1e-13]} {Smed: dd_Smed_v6_10315_0_2, dd_Smed_v6_10315_0_2, [Score=691, Expect=0.0]} {RNA1509_59703} {RNA1310_2710} {RNA815_17469}
85. MligTC455_18920 299 6.22 Mlig455_052039

Neo: -

Age: Down-Up-Down

Region-enriched R8: 3.175/0.01587

RTN4R 3.335 - 0.705 - 0.862 0.788 0.980 Mlig455_052039 {REF} {Length: 1911} {Pfam: Leucine rich repeat [PF13855.8, score=113.0]; Leucine Rich repeats (2 copies) [PF12799.9, score=46.5]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=24.5]} {Human: ENSG00000040608, RTN4R, reticulon 4 receptor, [Score=73.2, Expect=2e-13]} {Mouse: ENSMUSG00000111113, Rtn4r, reticulon 4 receptor, [Score=72.8, Expect=2e-13]; ENSMUSG00000043811, Rtn4r, reticulon 4 receptor, [Score=72.8, Expect=2e-13]} {Dmel: FBgn0004364, 18w, 18 wheeler, [Score=71.2, Expect=7e-13]} {Celegans: WBGene00001443, fli-1, Protein flightless-1 homolog, [Score=56.6, Expect=2e-08]} {Smed: dd_Smed_v6_12111_0_1, dd_Smed_v6_12111_0_1, [Score=48.1, Expect=8e-06]} {RNA1310_19257.1} {RNA815_9099}
86. MligTC455_47808 151 3.15 Mlig455_066806

Neo: -

Age: -

STAC2 3.324 0.766 - - 0.761 0.991 0.806 Mlig455_066806 {REF} {Length: 4661} {Pfam: SH3 domain [PF00018.30, score=41.7]; Variant SH3 domain [PF14604.8, score=35.5]} {Human: ENSG00000141750, STAC2, SH3 and cysteine rich domain 2, [RH, Score=72.8, Expect=1e-12]} {Mouse: ENSMUSG00000017400, Stac2, SH3 and cysteine rich domain 2, [RH, Score=72.0, Expect=2e-12]} {Dmel: FBgn0263980, CG43729, [RH, Score=149, Expect=5e-36]} {Celegans: WBGene00006791, unc-57, Endophilin-A homolog, [Score=53.9, Expect=2e-08]} {Smed: dd_Smed_v6_14652_0_1, dd_Smed_v6_14652_0_1, [Score=172, Expect=1e-43]} {RNA1509_54523} {RNA1310_1618} {RNA815_6997}
87. MligTC455_49457 1225 25.52 Mlig455_005617, Mlig455_014432, Mlig455_070181

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.375

3.302 0.710 0.867 - 0.761 - 0.964

Mlig455_005617 {REF} {Length: 1304} {RNA1509_48463} {RNA1310_46663, RNA1509_48463} {RNA1509_48463, RNA815_4404.1}

Mlig455_014432 {REF} {Length: 1338} {RNA1509_48463} {RNA1310_46663} {RNA815_4404.1}

Mlig455_070181 {REF} {Length: 1176} {RNA1509_47545, RNA1509_48463} {RNA1310_46663, RNA1509_47545} {RNA1509_47545, RNA815_4404.1}
88. MligTC455_27313 61 1.27 Mlig455_031814, Mlig455_047613

Neo: -

Age: -

WSCD2 3.3 0.765 - - 0.869 0.714 0.952

Mlig455_031814 {REF} {Length: 844} {Pfam: WSC domain [PF01822.21, score=66.1]; PAN domain [PF00024.28, score=19.7]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=62.0, Expect=7e-11]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=60.5, Expect=1e-10]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=56.6, Expect=3e-09]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=48.5, Expect=1e-06]} {RNA1509_43359} {RNA1310_33892} {RNA815_23776.1}

Mlig455_047613 {REF} {Length: 843} {Pfam: WSC domain [PF01822.21, score=52.5]; PAN domain [PF00024.28, score=19.2]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=52.0, Expect=5e-08]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=48.9, Expect=4e-07]} {RNA1509_43359} {RNA1310_33892} {RNA815_23776.1}
89. MligTC455_44170 360 7.5 Mlig455_025145

Neo: -

Age: logFC(26M/2M)=-0.567

ATP10D 3.291 0.781 - 0.718 0.836 - 0.956 Mlig455_025145 {REF} {Length: 6187} {TRANSSPLICED} {Pfam: Phospholipid-translocating ATPase N-terminal [PF16209.7, score=77.9]; E1-E2 ATPase [PF00122.22, score=31.1]} {Human: ENSG00000145246, ATP10D, ATPase phospholipid transporting 10D (putative), [Score=414, Expect=8e-130]; ENSG00000206190, ATP10A, ATPase phospholipid transporting 10A (putative), [Score=413, Expect=2e-137]; ENSG00000118322, ATP10B, ATPase phospholipid transporting 10B (putative), [Score=399, Expect=3e-124]} {Mouse: ENSMUSG00000046808, Atp10d, ATPase, class V, type 10D, [Score=414, Expect=2e-129]; ENSMUSG00000025324, Atp10a, ATPase, class V, type 10A, [Score=410, Expect=6e-128]} {Dmel: FBgn0032120, CG33298, [Score=394, Expect=2e-122]} {Celegans: WBGene00012360, tat-3, Phospholipid-transporting ATPase, [Score=416, Expect=5e-131]} {Smed: dd_Smed_v6_5042_0_1, dd_Smed_v6_5042_0_1, [Score=430, Expect=7e-136]} {RNA1509_3928} {RNA1310_991} {RNA815_151.1}
90. MligTC455_47975 31 0.64 Mlig455_018682, Mlig455_043427

Neo: -

Age: Up-Down-Down

ISL1 3.289 0.780 - - 0.796 0.750 0.963

Mlig455_018682 {REF} {Length: 3387} {Pfam: LIM domain [PF00412.24, score=95.5]; Homeodomain [PF00046.31, score=55.3]; Homeobox KN domain [PF05920.13, score=23.7]} {Human: ENSG00000016082, ISL1, ISL LIM homeobox 1, [Score=202, Expect=6e-60]} {Mouse: ENSMUSG00000042258, Isl1, ISL1 transcription factor, LIM/homeodomain, [Score=202, Expect=4e-60]} {Dmel: FBgn0003896, tup, tailup, [RH, Score=178, Expect=3e-49]} {Celegans: WBGene00002989, lim-7, CeLIM-7; LIM domain family, [RH, Score=228, Expect=5e-69]} {Smed: dd_Smed_v6_8820_0_1, dd_Smed_v6_8820_0_1, [Score=320, Expect=1e-103]} {RNA1310_20628} {RNA815_37694}

Mlig455_043427 {REF} {Length: 3365} {Pfam: LIM domain [PF00412.24, score=77.4]; Homeodomain [PF00046.31, score=53.3]; Homeobox KN domain [PF05920.13, score=21.8]} {Human: ENSG00000016082, ISL1, ISL LIM homeobox 1, [Score=167, Expect=2e-46]} {Mouse: ENSMUSG00000042258, Isl1, ISL1 transcription factor, LIM/homeodomain, [Score=167, Expect=1e-46]; ENSMUSG00000032318, Isl2, insulin related protein 2 (islet 2), [Score=160, Expect=4e-44]} {Dmel: FBgn0003896, tup, tailup, [Score=144, Expect=1e-37]} {Celegans: WBGene00002989, lim-7, CeLIM-7; LIM domain family, [Score=204, Expect=6e-60]} {Smed: dd_Smed_v6_8820_0_1, dd_Smed_v6_8820_0_1, [Score=274, Expect=7e-86]} {RNA1310_20628} {RNA815_37694}
91. MligTC455_31998 283 5.91 Mlig455_067851

Neo: -

Age: -

3.287 0.741 - 0.802 - 0.794 0.950 Mlig455_067851 {REF} {Length: 2274} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=56.5]} {Smed: dd_Smed_v6_7249_0_1, dd_Smed_v6_7249_0_1, [Score=142, Expect=6e-39]} {RNA1509_24876, RNA1509_54205} {RNA1310_15051, RNA1509_24876, RNA1509_54205} {RNA1509_24876, RNA1509_54205, RNA815_26796}
92. MligTC455_44171 367 7.64 Mlig455_063907

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.658

ATP10A 3.283 0.806 - 0.709 0.818 - 0.950 Mlig455_063907 {REF} {Length: 5440} {TRANSSPLICED} {Pfam: Phospholipid-translocating P-type ATPase C-terminal [PF16212.7, score=210.9]; Phospholipid-translocating ATPase N-terminal [PF16209.7, score=76.7]; haloacid dehalogenase-like hydrolase [PF00702.28, score=55.6]; Cation transport ATPase (P-type) [PF13246.8, score=45.4]; E1-E2 ATPase [PF00122.22, score=29.4]} {Human: ENSG00000206190, ATP10A, ATPase phospholipid transporting 10A (putative), [RH, Score=905, Expect=0.0]; ENSG00000118322, ATP10B, ATPase phospholipid transporting 10B (putative), [RH, Score=899, Expect=0.0]; ENSG00000145246, ATP10D, ATPase phospholipid transporting 10D (putative), [RH, Score=880, Expect=0.0]} {Mouse: ENSMUSG00000025324, Atp10a, ATPase, class V, type 10A, [RH, Score=907, Expect=0.0]; ENSMUSG00000055415, Atp10b, ATPase, class V, type 10B, [RH, Score=888, Expect=0.0]} {Dmel: FBgn0032120, CG33298, [Score=483, Expect=9e-146]} {Celegans: WBGene00012360, tat-3, Phospholipid-transporting ATPase, [Score=454, Expect=5e-136]} {Smed: dd_Smed_v6_13628_0_1, dd_Smed_v6_13628_0_1, [Score=831, Expect=0.0]} {RNA1509_3928} {RNA1310_991, RNA1509_3928} {RNA1509_3928, RNA815_151.1}
93. MligTC455_47094 240 5.01 Mlig455_014204

Neo: -

Age: logFC(26M/2M)=-0.357

3.268 - 0.742 - 0.950 0.706 0.870 Mlig455_014204 {REF} {Length: 3346} {Smed: dd_Smed_v6_4351_0_1, dd_Smed_v6_4351_0_1, [RH, Score=238, Expect=1e-74]} {RNA1509_35661} {RNA1310_8437, RNA1509_35661} {RNA1509_35661, RNA815_15552}
94. MligTC455_42391 1050 21.88 Mlig455_010516, Mlig455_061820, Mlig455_061856, Mlig455_061864

Neo: -

Age: Down-Up-Up

3.244 0.729 - 0.957 - 0.819 0.739

Mlig455_010516 {REF} {Length: 729} {RNA1509_38791} {RNA1310_69853, RNA1509_38791} {RNA1509_38791, RNA815_39199}

Mlig455_061820 {REF} {Length: 705} {RNA1509_38791} {RNA1310_69853} {RNA815_39199}

Mlig455_061856 {REF} {Length: 708} {RNA1509_38791} {RNA1310_69853} {RNA815_39199}

Mlig455_061864 {REF} {Length: 1146} {RNA1509_38791} {RNA1310_69853} {RNA815_39199}
95. MligTC455_47807 2664 55.5 Mlig455_050143

Neo: -

Age: -

Region-specific R2: 3.807

Region-enriched R2: 2.561/0.00001

3.226 0.708 - - 0.733 0.956 0.829 Mlig455_050143 {REF} {Length: 1560} {RNA1509_1605, RNA1509_28756} {RNA1310_30659.1, RNA1509_28756} {RNA1509_28756, RNA815_13807}
96. MligTC455_47670 709 14.77 Mlig455_064585

Neo: -

Age: -

Region-enriched R2: 1.616/0.00648

3.217 - 0.715 - 0.804 0.741 0.957 Mlig455_064585 {REF} {Length: 1016} {RNA1509_15853} {RNA1310_37053} {RNA815_24569.1}
97. MligTC455_37786 1733 36.1 Mlig455_019324, Mlig455_019438, Mlig455_019545

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.251

3.211 - - 0.704 0.824 0.726 0.957

Mlig455_019324 {REF} {Length: 3964} {Pfam: FAM216B protein family [PF15107.8, score=19.0]} {RNA1509_21362, RNA1509_30523} {RNA1310_10336.1, RNA1509_30523} {RNA1509_30523, RNA815_4271}

Mlig455_019438 {REF} {Length: 1903} {Pfam: FAM216B protein family [PF15107.8, score=19.0]} {RNA1509_21362} {RNA1310_10336.1, RNA1509_21362} {RNA1509_21362, RNA815_4271}

Mlig455_019545 {REF} {Length: 3361} {Pfam: FAM216B protein family [PF15107.8, score=18.9]} {RNA1509_21362} {RNA1310_10336.1} {RNA815_4271}
98. MligTC455_25588 1046 21.8 Mlig455_029794

Neo: -

Age: -

Region-enriched R2: 2.896/0.00002

3.17 0.709 0.736 - - 0.980 0.745 Mlig455_029794 {REF} {Length: 1354} {Pfam: Domain of unknown function (DUF4573) [PF15140.8, score=40.1]; Domain of unknown function (DUF1848) [PF08902.13, score=20.8]} {RNA1509_17753} {RNA1310_70608} {RNA815_1498.1}
99. MligTC455_38368 107 2.24 Mlig455_026435, Mlig455_044757

Neo: -

Age: Up-Down-Down

SSUH2 2.912 - - - 0.976 0.966 0.970

Mlig455_026435 {REF} {Length: 1789} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [RH, Score=233, Expect=1e-72]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [RH, Score=195, Expect=1e-58]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=117, Expect=3e-29]} {RNA1509_6425} {RNA1310_32434} {RNA815_16161}

Mlig455_044757 {REF} {Length: 883} {TRANSSPLICED} {RNA1509_28356} {RNA1310_61125} {RNA815_53103}
100. MligTC455_14130 101 2.11 Mlig455_028802

Neo: -

Age: -

Region-enriched R7: 4.171/0.00325

2.89 - - - 0.953 0.955 0.982 Mlig455_028802 {REF} {Length: 1282} {Pfam: Lectin C-type domain [PF00059.23, score=21.4]} {RNA1509_20946} {RNA1310_33562} {RNA815_30982}

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