Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_23747 | 911 | 18.99 | Mlig455_029661 | Neo: - Age: - Region-enriched R8: 1.483/0.03070 |
RYR2 | Mlig455_029661 {REF} {Length: 16009} {Pfam: RIH domain [PF01365.23, score=380.6]; RyR domain [PF02026.18, score=278.1]; Inositol 1,4,5-trisphosphate/ryanodine receptor [PF08709.13, score=160.6]; SPRY domain [PF00622.30, score=160.1]; MIR domain [PF02815.21, score=149.6]; Ryanodine Receptor TM 4-6 [PF06459.14, score=119.4]; RyR and IP3R Homology associated [PF08454.13, score=108.6]; Ion transport protein [PF00520.33, score=45.5]; EF hand [PF00036.34, score=43.1]; EF-hand domain pair [PF13499.8, score=39.4]; EF hand [PF13202.8, score=36.6]; EF-hand domain pair [PF13833.8, score=34.5]; EF-hand domain [PF13405.8, score=25.2]} {Human: ENSG00000198626, RYR2, ryanodine receptor 2, [RH, Score=3262, Expect=0.0]} {Mouse: ENSMUSG00000021313, Ryr2, ryanodine receptor 2, cardiac, [RH, Score=3244, Expect=0.0]} {Dmel: FBgn0011286, RyR, Ryanodine receptor, [RH, Score=2369, Expect=0.0]} {Celegans: WBGene00006801, unc-68, [RH, Score=1419, Expect=0.0]} {Smed: dd_Smed_v6_5582_0_1, dd_Smed_v6_5582_0_1, [RH, Score=4415, Expect=0.0]} {RNA1509_827} {RNA1310_30.1} {RNA815_76.1} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -0.547 | 4.478 | 0.54284 | 1.00000 | |
RegionR2 | 1.274 | 4.478 | 0.00320 | 0.04794 | |
RegionR3 | -0.253 | 4.478 | 0.45176 | 0.96303 | |
RegionR4 | -1.156 | 4.478 | 0.00862 | 0.05461 | |
RegionR5 | -1.124 | 4.478 | 0.00072 | 0.00788 | |
RegionR6 | -0.35 | 4.478 | 0.31326 | 0.90229 | |
RegionR7 | 0.674 | 4.478 | 0.08488 | 0.56088 | |
RegionR8 | 1.483 | 4.478 | 0.00056 | 0.03070 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | 0.873 | 4.478 | 0.54493 | 1.00000 | |
RegenerationR2 | -0.068 | 4.478 | 0.85555 | 1.00000 | |
RegenerationR3 | 0.048 | 4.478 | 0.90856 | 1.00000 | |
RegenerationR4 | -0.39 | 4.478 | 0.40131 | 0.81432 | |
RegenerationR5 | -0.05 | 4.478 | 0.90657 | 1.00000 | |
RegenerationR6 | -0.662 | 4.478 | 0.16225 | 0.49131 | |
RegenerationBL | -0.307 | 4.478 | 0.55024 | 0.90713 | |
RegenerationTP | -1.179 | 4.478 | 0.02526 | 0.26887 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_23747 | 911 | 18.99 | Mlig455_029661 | Neo: - Age: - Region-enriched R8: 1.483/0.03070 |
RYR2 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_029661 {REF} {Length: 16009} {Pfam: RIH domain [PF01365.23, score=380.6]; RyR domain [PF02026.18, score=278.1]; Inositol 1,4,5-trisphosphate/ryanodine receptor [PF08709.13, score=160.6]; SPRY domain [PF00622.30, score=160.1]; MIR domain [PF02815.21, score=149.6]; Ryanodine Receptor TM 4-6 [PF06459.14, score=119.4]; RyR and IP3R Homology associated [PF08454.13, score=108.6]; Ion transport protein [PF00520.33, score=45.5]; EF hand [PF00036.34, score=43.1]; EF-hand domain pair [PF13499.8, score=39.4]; EF hand [PF13202.8, score=36.6]; EF-hand domain pair [PF13833.8, score=34.5]; EF-hand domain [PF13405.8, score=25.2]} {Human: ENSG00000198626, RYR2, ryanodine receptor 2, [RH, Score=3262, Expect=0.0]} {Mouse: ENSMUSG00000021313, Ryr2, ryanodine receptor 2, cardiac, [RH, Score=3244, Expect=0.0]} {Dmel: FBgn0011286, RyR, Ryanodine receptor, [RH, Score=2369, Expect=0.0]} {Celegans: WBGene00006801, unc-68, [RH, Score=1419, Expect=0.0]} {Smed: dd_Smed_v6_5582_0_1, dd_Smed_v6_5582_0_1, [RH, Score=4415, Expect=0.0]} {RNA1509_827} {RNA1310_30.1} {RNA815_76.1} |
2. | MligTC455_45820 | 864 | 18 | Mlig455_029390 | Neo: - Age: logFC(26M/2M)=0.420 Region-enriched R2: 2.360/0.02053 |
TYW5 | 1.732 | - | 0.953 | - | - | - | 0.779 | Mlig455_029390 {REF} {Length: 1885} {Pfam: Cupin-like domain [PF13621.8, score=119.9]; EF hand [PF13202.8, score=23.2]} {Human: ENSG00000162971, TYW5, tRNA-yW synthesizing protein 5, [Score=64.3, Expect=9e-11]} {Mouse: ENSMUSG00000030752, Kdm8, lysine (K)-specific demethylase 8, [Score=70.9, Expect=9e-13]} {Dmel: FBgn0035166, CG13902, [Score=64.3, Expect=6e-11]} {Celegans: WBGene00007387, jmjd-5, JuMonJi (Transcription factor) Domain protein, [Score=53.1, Expect=3e-07]} {Smed: dd_Smed_v6_11273_0_1, dd_Smed_v6_11273_0_1, [Score=224, Expect=1e-68]} {RNA1509_1841, RNA1509_6132} {RNA1310_16511, RNA1509_6132} {RNA1509_6132, RNA815_6144} |
3. | MligTC455_31575 | 985 | 20.52 | Mlig455_035809, Mlig455_058366 | Neo: - Age: - |
BCHE | 1.706 | - | - | 0.748 | 0.958 | - | - | Mlig455_035809 {REF} {Length: 4561} {Pfam: Carboxylesterase family [PF00135.30, score=431.7]; alpha/beta hydrolase fold [PF07859.15, score=32.4]} {Human: ENSG00000114200, BCHE, butyrylcholinesterase, [RH, Score=316, Expect=6e-98]; ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [RH, Score=303, Expect=1e-92]} {Mouse: ENSMUSG00000027792, Bche, butyrylcholinesterase, [RH, Score=314, Expect=5e-97]; ENSMUSG00000023328, Ache, acetylcholinesterase, [RH, Score=300, Expect=1e-91]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [RH, Score=265, Expect=2e-78]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [RH, Score=330, Expect=5e-103]} {Smed: dd_Smed_v6_4800_0_1, dd_Smed_v6_4800_0_1, [RH, Score=405, Expect=3e-131]} {RNA1509_10899} {RNA1310_7772.1} {RNA815_3647} Mlig455_058366 {REF} {Length: 3155} {Pfam: Carboxylesterase family [PF00135.30, score=432.0]; alpha/beta hydrolase fold [PF07859.15, score=32.4]} {Human: ENSG00000114200, BCHE, butyrylcholinesterase, [RH, Score=316, Expect=2e-98]; ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [RH, Score=303, Expect=4e-93]} {Mouse: ENSMUSG00000027792, Bche, butyrylcholinesterase, [RH, Score=314, Expect=2e-97]; ENSMUSG00000023328, Ache, acetylcholinesterase, [RH, Score=300, Expect=5e-92]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [RH, Score=266, Expect=4e-79]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [RH, Score=330, Expect=2e-103]} {Smed: dd_Smed_v6_4800_0_1, dd_Smed_v6_4800_0_1, [RH, Score=405, Expect=8e-132]} {RNA1509_10899} {RNA1310_7772.1} {RNA815_3647} |
4. | MligTC455_47707 | 325 | 6.78 | Mlig455_067545 | Neo: - Age: - |
VEPH1 | 1.653 | - | - | 0.702 | - | - | 0.951 | Mlig455_067545 {REF} {Length: 4743} {TRANSSPLICED} {Human: ENSG00000197415, VEPH1, ventricular zone expressed PH domain containing 1, [RH, Score=105, Expect=1e-22]} {Mouse: ENSMUSG00000027831, Veph1, ventricular zone expressed PH domain-containing 1, [RH, Score=98.2, Expect=2e-20]} {Dmel: FBgn0023001, melt, melted, [RH, Score=97.8, Expect=2e-20]} {Celegans: WBGene00019615, K10B4.3, Protein melted homolog, [RH, Score=101, Expect=9e-22]} {RNA1509_27116} {RNA1310_3335.2, RNA1509_27116} {RNA1509_27116, RNA815_7388} |
5. | MligTC455_48876 | 687 | 14.31 | Mlig455_064167 | Neo: - Age: - Regeneration-downregulated R2: -1.492 Regeneration-depleted R2: -1.492 |
CACNB2 | 0.966 | - | 0.966 | - | - | - | - | Mlig455_064167 {REF} {Length: 3167} {TRANSSPLICED} {Pfam: Guanylate kinase [PF00625.23, score=139.1]; Voltage gated calcium channel subunit beta domain 4Aa N terminal [PF12052.10, score=24.3]} {Human: ENSG00000165995, CACNB2, calcium voltage-gated channel auxiliary subunit beta 2, [Score=446, Expect=4e-149]; ENSG00000067191, CACNB1, calcium voltage-gated channel auxiliary subunit beta 1, [Score=426, Expect=8e-143]} {Mouse: ENSMUSG00000057914, Cacnb2, calcium channel, voltage-dependent, beta 2 subunit, [Score=437, Expect=1e-145]} {Dmel: FBgn0259822, Ca-beta, Ca2+-channel-protein-beta-subunit, [Score=460, Expect=2e-157]} {Celegans: WBGene00000368, ccb-1, Calcium Channel, Beta subunit, [Score=325, Expect=3e-104]} {Smed: dd_Smed_v6_9267_0_1, dd_Smed_v6_9267_0_1, [RH, Score=469, Expect=1e-159]} {RNA1509_13952} {RNA1310_9640} {RNA815_20879} |
6. | MligTC455_29465 | 590 | 12.3 | Mlig455_032544 | Neo: - Age: - |
MADD | 0.965 | - | - | - | - | - | 0.965 | Mlig455_032544 {REF} {Length: 6532} {Human: ENSG00000110514, MADD, MAP kinase activating death domain, [Score=384, Expect=2e-116]} {Mouse: ENSMUSG00000040687, Madd, MAP-kinase activating death domain, [Score=386, Expect=9e-118]} {Dmel: FBgn0030613, Rab3-GEF, Rab3 GDP-GTP exchange factor, [Score=325, Expect=1e-95]} {Celegans: WBGene00000086, aex-3, MAP kinase-activating death domain protein, [Score=266, Expect=6e-76]} {Smed: dd_Smed_v6_8355_0_5, dd_Smed_v6_8355_0_5, [Score=322, Expect=7e-99]} {RNA1509_28698} {RNA1310_18046, RNA1509_28698} {RNA1509_28698, RNA815_6666} |
7. | MligTC455_39097 | 57 | 1.18 | Mlig455_051961 | Neo: - Age: - Region-enriched R4: 5.550/0.02060 |
0.958 | - | - | - | - | 0.958 | - | Mlig455_051961 {REF} {Length: 1972} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=65.0]} {RNA1509_13138} {RNA1310_34740} {RNA815_15663} | |
8. | MligTC455_40201 | 607 | 12.65 | Mlig455_052028 | Neo: - Age: logFC(26M/2M)=-0.526 |
DCLK3 | 0.954 | - | 0.954 | - | - | - | - | Mlig455_052028 {REF} {Length: 3990} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=245.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=121.1]; Doublecortin [PF03607.19, score=80.8]; Fungal protein kinase [PF17667.3, score=26.5]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=19.0]} {Human: ENSG00000163673, DCLK3, doublecortin like kinase 3, [RH, Score=370, Expect=2e-115]; ENSG00000133083, DCLK1, doublecortin like kinase 1, [RH, Score=358, Expect=8e-110]} {Mouse: ENSMUSG00000032500, Dclk3, doublecortin-like kinase 3, [RH, Score=369, Expect=3e-113]; ENSMUSG00000027797, Dclk1, doublecortin-like kinase 1, [RH, Score=357, Expect=4e-109]} {Dmel: FBgn0261387, CG17528, [RH, Score=295, Expect=7e-87]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [RH, Score=231, Expect=1e-63]} {Smed: dd_Smed_v6_12689_0_1, dd_Smed_v6_12689_0_1, [RH, Score=351, Expect=2e-105]} {RNA1509_13597} {RNA1310_2158.1} {RNA815_2598} |
9. | MligTC455_40202 | 595 | 12.39 | Mlig455_057253 | Neo: - Age: logFC(26M/2M)=-0.440 |
DCLK3 | 0.954 | - | 0.954 | - | - | - | - | Mlig455_057253 {REF} {Length: 4012} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=245.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=121.1]; Doublecortin [PF03607.19, score=80.9]; Fungal protein kinase [PF17667.3, score=25.3]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=18.9]} {Human: ENSG00000163673, DCLK3, doublecortin like kinase 3, [RH, Score=371, Expect=1e-115]; ENSG00000133083, DCLK1, doublecortin like kinase 1, [RH, Score=358, Expect=2e-113]} {Mouse: ENSMUSG00000032500, Dclk3, doublecortin-like kinase 3, [RH, Score=370, Expect=1e-113]; ENSMUSG00000027797, Dclk1, doublecortin-like kinase 1, [RH, Score=357, Expect=4e-109]} {Dmel: FBgn0261387, CG17528, [RH, Score=296, Expect=6e-87]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [RH, Score=231, Expect=1e-63]} {Smed: dd_Smed_v6_12689_0_1, dd_Smed_v6_12689_0_1, [RH, Score=352, Expect=1e-105]} {RNA1509_13597, RNA1509_49808} {RNA1310_2158.1, RNA1509_13597, RNA1509_49808} {RNA1509_13597, RNA1509_49808, RNA815_2598} |
10. | MligTC455_49315 | 516 | 10.75 | Mlig455_070598 | Neo: - Age: logFC(26M/2M)=-0.322 |
SLC24A3 | 0.953 | - | 0.953 | - | - | - | - | Mlig455_070598 {REF} {Length: 3827} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=176.9]} {Human: ENSG00000185052, SLC24A3, solute carrier family 24 member 3, [RH, Score=427, Expect=9e-142]} {Mouse: ENSMUSG00000063873, Slc24a3, solute carrier family 24 (sodium/potassium/calcium exchanger), member 3, [RH, Score=423, Expect=5e-141]} {Dmel: FBgn0037238, CG1090, [Score=384, Expect=2e-125]} {Celegans: WBGene00003569, ncx-4, Na/Ca eXchangers, [RH, Score=315, Expect=3e-99]} {Smed: dd_Smed_v6_7121_0_1, dd_Smed_v6_7121_0_1, [Score=432, Expect=6e-146]} {RNA1509_8142} {RNA1310_7488, RNA1509_8142} {RNA1509_8142, RNA815_3083.1} |
11. | MligTC455_22714 | 401 | 8.36 | Mlig455_023345 | Neo: - Age: Down-Up-Down |
0.951 | - | 0.951 | - | - | - | - | Mlig455_023345 {REF} {Length: 3876} {RNA1509_17376, RNA1509_31558} {RNA1310_6954, RNA1509_17376, RNA1509_31558} {RNA1509_17376, RNA1509_31558, RNA815_8376.1} | |
12. | MligTC455_37448 | 714 | 14.87 | Mlig455_007744, Mlig455_066068 | Neo: - Age: Down-Down-Up |
RP1L1 | 0.951 | - | - | - | - | 0.951 | - | Mlig455_007744 {REF} {Length: 3944} {Human: ENSG00000285131, RP1L1, RP1 like 1, [Score=55.1, Expect=1e-06]; ENSG00000196440, ARMCX4, armadillo repeat containing X-linked 4, [Score=53.1, Expect=2e-06]} {Mouse: ENSMUSG00000020396, Nefh, neurofilament, heavy polypeptide, [Score=85.9, Expect=2e-16]} {Dmel: FBgn0029807, CG3108, [Score=72.4, Expect=2e-12]} {RNA1509_52676} {RNA1310_13856} {RNA815_2540.1} Mlig455_066068 {REF} {Length: 3431} {Human: ENSG00000285131, RP1L1, RP1 like 1, [Score=56.2, Expect=3e-07]; ENSG00000100285, NEFH, neurofilament heavy, [Score=54.3, Expect=1e-06]} {Mouse: ENSMUSG00000020396, Nefh, neurofilament, heavy polypeptide, [Score=96.7, Expect=7e-20]} {Dmel: FBgn0029807, CG3108, [Score=71.2, Expect=4e-12]} {RNA1509_52676} {RNA1310_13856} {RNA815_18535} |
13. | MligTC455_19591 | 208 | 4.33 | Mlig455_067126 | Neo: - Age: logFC(26M/2M)=-0.334 |
ANKRD50 | 0.95 | - | - | - | - | - | 0.950 | Mlig455_067126 {REF} {Length: 5329} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=112.8]; Ankyrin repeats (many copies) [PF13637.8, score=55.3]; Ankyrin repeat [PF00023.32, score=48.3]; Ankyrin repeats (many copies) [PF13857.8, score=45.6]; Ankyrin repeat [PF13606.8, score=39.3]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=75.9, Expect=5e-13]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=77.0, Expect=2e-13]} {Dmel: FBgn0043884, mask, multiple ankyrin repeats single KH domain, [Score=64.7, Expect=6e-10]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=61.2, Expect=6e-09]} {Smed: dd_Smed_v6_12936_0_1, dd_Smed_v6_12936_0_1, [Score=63.9, Expect=6e-10]} {RNA1509_9127} {RNA1310_1490, RNA1509_9127} {RNA1509_9127, RNA815_555} |