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Results for MligTC455_23856

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_23856 36 0.74 Mlig455_011275

Neo: -

Age: -

KCNN2 Mlig455_011275 {REF} {Length: 5211} {Pfam: Calcium-activated SK potassium channel [PF03530.16, score=145.7]; Calmodulin binding domain [PF02888.18, score=113.6]; Ion channel [PF07885.18, score=52.3]} {Human: ENSG00000080709, KCNN2, potassium calcium-activated channel subfamily N member 2, [RH, Score=538, Expect=0.0]; ENSG00000143603, KCNN3, potassium calcium-activated channel subfamily N member 3, [RH, Score=530, Expect=0.0]; ENSG00000105642, KCNN1, potassium calcium-activated channel subfamily N member 1, [RH, Score=515, Expect=2e-178]} {Mouse: ENSMUSG00000054477, Kcnn2, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2, [RH, Score=539, Expect=0.0]; ENSMUSG00000000794, Kcnn3, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3, [RH, Score=530, Expect=0.0]} {Dmel: FBgn0029761, SK, small conductance calcium-activated potassium channel, [RH, Score=602, Expect=0.0]} {Celegans: WBGene00008570, kcnl-2, KCNL-2 variant; KCNN (Potassium K ChaNNel, calcium activated)-Like, [RH, Score=423, Expect=2e-140]} {Smed: dd_Smed_v6_14006_0_1, dd_Smed_v6_14006_0_1, [RH, Score=540, Expect=0.0]} {RNA1509_39273} {RNA1310_12409} {RNA815_5551}

Cumulative graph for MligTC455_23856

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.77 0.842 1.00000 1.00000
RegionR2 -0.363 0.842 1.00000 1.00000
RegionR3 -1.303 0.842 1.00000 1.00000
RegionR4 3.176 0.842 0.11046 0.32860
RegionR5 0.495 0.842 0.64729 0.99920
RegionR6 0.372 0.842 0.94338 1.00000
RegionR7 -1.765 0.842 1.00000 1.00000
RegionR8 0.159 0.842 0.99999 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 4.86 0.842 0.89275 1.00000
RegenerationR2 -0.329 0.842 0.71869 0.96295
RegenerationR3 -1.985 0.842 0.94629 1.00000
RegenerationR4 -2.388 0.842 0.33850 0.77071
RegenerationR5 -1.076 0.842 0.59198 0.90654
RegenerationR6 -2.379 0.842 0.36590 0.70946
RegenerationBL -2.981 0.842 0.99989 1.00000
RegenerationTP -1.929 0.842 0.99987 1.00000


Genes with expression patterns similar to MligTC455_23856

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_23856 36 0.74 Mlig455_011275

Neo: -

Age: -

KCNN2 2 - - 1.000 1.000 - - Mlig455_011275 {REF} {Length: 5211} {Pfam: Calcium-activated SK potassium channel [PF03530.16, score=145.7]; Calmodulin binding domain [PF02888.18, score=113.6]; Ion channel [PF07885.18, score=52.3]} {Human: ENSG00000080709, KCNN2, potassium calcium-activated channel subfamily N member 2, [RH, Score=538, Expect=0.0]; ENSG00000143603, KCNN3, potassium calcium-activated channel subfamily N member 3, [RH, Score=530, Expect=0.0]; ENSG00000105642, KCNN1, potassium calcium-activated channel subfamily N member 1, [RH, Score=515, Expect=2e-178]} {Mouse: ENSMUSG00000054477, Kcnn2, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2, [RH, Score=539, Expect=0.0]; ENSMUSG00000000794, Kcnn3, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3, [RH, Score=530, Expect=0.0]} {Dmel: FBgn0029761, SK, small conductance calcium-activated potassium channel, [RH, Score=602, Expect=0.0]} {Celegans: WBGene00008570, kcnl-2, KCNL-2 variant; KCNN (Potassium K ChaNNel, calcium activated)-Like, [RH, Score=423, Expect=2e-140]} {Smed: dd_Smed_v6_14006_0_1, dd_Smed_v6_14006_0_1, [RH, Score=540, Expect=0.0]} {RNA1509_39273} {RNA1310_12409} {RNA815_5551}
2. MligTC455_48128 18 0.37 Mlig455_052326

Neo: -

Age: -

1.797 - - 0.835 0.962 - - Mlig455_052326 {REF} {Length: 3582} {RNA1310_42908} {RNA815_22744}
3. MligTC455_13474 28 0.59 Mlig455_037468

Neo: -

Age: logFC(26M/2M)=-1.035

AGTR2 1.79 - - 0.835 0.955 - - Mlig455_037468 {REF} {Length: 2762} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=46.1]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=30.6]} {Human: ENSG00000180772, AGTR2, angiotensin II receptor type 2, [Score=52.4, Expect=7e-07]; ENSG00000182631, RXFP3, relaxin family peptide receptor 3, [Score=50.1, Expect=5e-06]; ENSG00000277069, RXFP3, relaxin family peptide receptor 3, [Score=50.1, Expect=5e-06]} {Mouse: ENSMUSG00000054988, Agtr1b, angiotensin II receptor, type 1b, [Score=52.8, Expect=4e-07]; ENSMUSG00000068122, Agtr2, angiotensin II receptor, type 2, [Score=52.4, Expect=5e-07]; ENSMUSG00000034677, Gpr142, G protein-coupled receptor 142, [Score=51.6, Expect=1e-06]} {Dmel: FBgn0035385, FMRFaR, FMRFamide Receptor, [Score=79.3, Expect=1e-15]} {Celegans: WBGene00016246, daf-37, G-protein coupled receptor daf-37, [Score=85.9, Expect=6e-18]} {Smed: dd_Smed_v6_31203_0_1, dd_Smed_v6_31203_0_1, [RH, Score=173, Expect=2e-49]} {RNA1310_71010}
4. MligTC455_46543 178 3.7 Mlig455_000344, Mlig455_067946

Neo: -

Age: -

Region-specific R2: 6.098

Region-enriched R2: 6.851/0.00000

1.711 - - 0.738 0.973 - -

Mlig455_000344 {REF} {Length: 1920} {RNA1310_82457} {RNA815_33120}

Mlig455_067946 {REF} {Length: 1217} {RNA1310_99435}
5. MligTC455_18445 21 0.43 Mlig455_048254, Mlig455_048287

Neo: -

Age: -

NMBR 1.705 - - 0.747 0.958 - -

Mlig455_048254 {REF} {Length: 2238} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=119.6]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=40.7]; Serpentine type 7TM GPCR chemoreceptor Srv [PF10323.11, score=37.5]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=25.8]} {Human: ENSG00000135577, NMBR, neuromedin B receptor, [Score=128, Expect=2e-32]; ENSG00000102239, BRS3, bombesin receptor subtype 3, [Score=125, Expect=4e-31]} {Mouse: ENSMUSG00000019865, Nmbr, neuromedin B receptor, [Score=129, Expect=5e-33]; ENSMUSG00000031364, Grpr, gastrin releasing peptide receptor, [Score=124, Expect=4e-31]} {Dmel: FBgn0050106, CCHa1-R, CCHamide-1 receptor, [Score=132, Expect=2e-33]} {Celegans: WBGene00009619, npr-6, NeuroPeptide Receptor family, [Score=88.6, Expect=7e-19]} {Smed: dd_Smed_v6_17567_0_1, dd_Smed_v6_17567_0_1, [Score=132, Expect=3e-34]} {RNA1310_54760}

Mlig455_048287 {REF} {Length: 2331} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=119.6]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=40.7]; Serpentine type 7TM GPCR chemoreceptor Srv [PF10323.11, score=37.5]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=25.8]} {Human: ENSG00000135577, NMBR, neuromedin B receptor, [Score=128, Expect=2e-32]; ENSG00000102239, BRS3, bombesin receptor subtype 3, [Score=125, Expect=3e-31]} {Mouse: ENSMUSG00000019865, Nmbr, neuromedin B receptor, [Score=129, Expect=8e-33]; ENSMUSG00000031364, Grpr, gastrin releasing peptide receptor, [Score=124, Expect=4e-31]} {Dmel: FBgn0050106, CCHa1-R, CCHamide-1 receptor, [Score=132, Expect=2e-33]} {Celegans: WBGene00009619, npr-6, NeuroPeptide Receptor family, [Score=88.6, Expect=6e-19]} {Smed: dd_Smed_v6_17567_0_1, dd_Smed_v6_17567_0_1, [Score=132, Expect=3e-34]} {RNA1310_54760}
6. MligTC455_46886 51 1.05 Mlig455_015258

Neo: -

Age: -

Region-enriched R2: 4.468/0.04690

PRKG2 1.703 - - 0.744 0.959 - - Mlig455_015258 {REF} {Length: 3110} {Pfam: Protein kinase domain [PF00069.27, score=225.4]; Cyclic nucleotide-binding domain [PF00027.31, score=118.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=117.9]; Kinase-like [PF14531.8, score=25.3]} {Human: ENSG00000138669, PRKG2, protein kinase cGMP-dependent 2, [RH, Score=668, Expect=0.0]} {Mouse: ENSMUSG00000029334, Prkg2, protein kinase, cGMP-dependent, type II, [RH, Score=669, Expect=0.0]} {Dmel: FBgn0000442, Pkg21D, Protein kinase, cGMP-dependent at 21D, [RH, Score=683, Expect=0.0]} {Celegans: WBGene00001173, egl-4, cGMP-dependent protein kinase egl-4, [Score=667, Expect=0.0]} {Smed: dd_Smed_v6_6967_0_1, dd_Smed_v6_6967_0_1, [RH, Score=672, Expect=0.0]} {RNA1509_26653} {RNA1310_15330.1} {RNA815_26005}
7. MligTC455_18265 16 0.34 Mlig455_008771

Neo: -

Age: -

PTH1R 1.691 - - 0.736 0.955 - - Mlig455_008771 {REF} {Length: 3138} {Pfam: 7 transmembrane receptor (Secretin family) [PF00002.26, score=188.4]; Hormone receptor domain [PF02793.24, score=94.5]} {Human: ENSG00000160801, PTH1R, parathyroid hormone 1 receptor, [RH, Score=231, Expect=4e-67]} {Mouse: ENSMUSG00000032492, Pth1r, parathyroid hormone 1 receptor, [RH, Score=232, Expect=1e-67]} {Dmel: FBgn0033932, Dh44-R1, Diuretic hormone 44 receptor 1, [RH, Score=147, Expect=6e-38]} {Celegans: WBGene00015735, pdfr-1, Calcitonin receptor-like protein 1, [Score=129, Expect=1e-31]} {Smed: dd_Smed_v6_16180_0_1, dd_Smed_v6_16180_0_1, [RH, Score=243, Expect=4e-74]} {RNA1310_30448} {RNA815_40945}
8. MligTC455_50601 21 0.44 Mlig455_018462

Neo: -

Age: -

1.684 - - 0.730 0.954 - - Mlig455_018462 {REF} {Length: 2878} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=164.0]} {Smed: dd_Smed_v6_37545_0_1, dd_Smed_v6_37545_0_1, [Score=117, Expect=1e-27]} {RNA1310_8235} {RNA815_10456.1}
9. MligTC455_15493 109 2.26 Mlig455_005712

Neo: -

Age: -

0.982 - - - 0.982 - - Mlig455_005712 {REF} {Length: 1705} {RNA1509_47692} {RNA1310_24839} {RNA815_13783}
10. MligTC455_17850 65 1.35 Mlig455_002427

Neo: -

Age: -

0.966 - - - 0.966 - - Mlig455_002427 {REF} {Length: 474} {NoTransDecoderORF} {RNA1310_58520.2} {RNA815_36774}
11. MligTC455_21861 166 3.46 Mlig455_001636

Neo: -

Age: -

FAM234B 0.966 - - - 0.966 - - Mlig455_001636 {REF} {Length: 2805} {Pfam: FG-GAP-like repeat [PF13517.8, score=32.1]; PQQ-like domain [PF13360.8, score=26.1]; PQQ enzyme repeat [PF01011.23, score=25.0]} {Human: ENSG00000084444, FAM234B, family with sequence similarity 234 member B, [RH, Score=60.8, Expect=7e-09]} {Mouse: ENSMUSG00000030207, Fam234b, family with sequence similarity 234, member B, [RH, Score=62.8, Expect=1e-09]} {Dmel: FBgn0038725, CG6184, [Score=192, Expect=2e-50]} {Smed: dd_Smed_v6_12614_0_1, dd_Smed_v6_12614_0_1, [Score=239, Expect=5e-67]} {RNA1509_34189} {RNA1310_7071, RNA1509_34189} {RNA1509_34189, RNA815_18304}
12. MligTC455_56421 59 1.23 Mlig455_066824

Neo: -

Age: -

0.964 - - - 0.964 - - Mlig455_066824 {REF} {Length: 413} {RNA1509_38728} {RNA1310_9789} {RNA815_21216}
13. MligTC455_47234 19 0.39 Mlig455_051300

Neo: -

Age: Down-Up-Down

SCNN1B 0.963 - - - 0.963 - - Mlig455_051300 {REF} {Length: 1753} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=169.2]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=57.4, Expect=5e-08]} {Mouse: ENSMUSG00000000216, Scnn1g, sodium channel, nonvoltage-gated 1 gamma, [Score=55.8, Expect=1e-07]} {Celegans: WBGene00003174, mec-10, Degenerin mec-10, [Score=57.8, Expect=2e-08]} {Smed: dd_Smed_v6_12037_0_1, dd_Smed_v6_12037_0_1, [Score=85.9, Expect=1e-17]} {RNA1310_54586}
14. MligTC455_53504 217 4.51 Mlig455_037385

Neo: -

Age: -

Region-enriched R2: 3.142/0.00738

CSMD1 0.963 - - - 0.963 - - Mlig455_037385 {REF} {Length: 2214} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=198.7]} {Human: ENSG00000183117, CSMD1, CUB and Sushi multiple domains 1, [Score=149, Expect=8e-37]} {Mouse: ENSMUSG00000028369, Svep1, sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1, [Score=136, Expect=7e-33]; ENSMUSG00000060924, Csmd1, CUB and Sushi multiple domains 1, [Score=134, Expect=5e-32]; ENSMUSG00000022311, Csmd3, CUB and Sushi multiple domains 3, [Score=133, Expect=9e-32]} {Dmel: FBgn0032797, Hasp, Hig-anchoring scaffold protein, [RH, Score=218, Expect=3e-60]} {Celegans: WBGene00002976, lev-9, [RH, Score=244, Expect=4e-72]} {Smed: dd_Smed_v6_13071_0_1, dd_Smed_v6_13071_0_1, [RH, Score=296, Expect=1e-91]} {RNA1509_55985} {RNA1310_12867.1, RNA1509_55985} {RNA1509_55985, RNA815_9157}
15. MligTC455_33099 20 0.42 Mlig455_023705

Neo: -

Age: -

0.96 - - - 0.960 - - Mlig455_023705 {REF} {Length: 1888} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_35225} {RNA1310_19456} {RNA815_41929}
16. MligTC455_38228 1245 25.95 Mlig455_062302

Neo: -

Age: -

Region-specific R2: 4.636

Region-enriched R2: 3.645/0.00011
Region-enriched R3: 2.442/0.00111

0.958 - - - 0.958 - - Mlig455_062302 {REF} {Length: 725} {RNA1509_22173, RNA1509_33106} {RNA1310_65747, RNA1509_22173, RNA1509_33106} {RNA1509_22173, RNA1509_33106, RNA815_15489}
17. MligTC455_18564 196 4.08 Mlig455_063527

Neo: -

Age: -

Region-enriched R2: 2.416/0.01839

PRKG2 0.957 - - - 0.957 - - Mlig455_063527 {REF} {Length: 2971} {Pfam: Protein kinase domain [PF00069.27, score=212.4]; Cyclic nucleotide-binding domain [PF00027.31, score=135.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=103.7]; Kinase-like [PF14531.8, score=24.8]} {Human: ENSG00000138669, PRKG2, protein kinase cGMP-dependent 2, [RH, Score=653, Expect=0.0]} {Mouse: ENSMUSG00000029334, Prkg2, protein kinase, cGMP-dependent, type II, [RH, Score=651, Expect=0.0]} {Dmel: FBgn0000442, Pkg21D, Protein kinase, cGMP-dependent at 21D, [RH, Score=662, Expect=0.0]} {Celegans: WBGene00001173, egl-4, cGMP-dependent protein kinase egl-4, [Score=655, Expect=0.0]} {Smed: dd_Smed_v6_6967_0_1, dd_Smed_v6_6967_0_1, [RH, Score=645, Expect=0.0]} {RNA1509_38353} {RNA1310_8466, RNA1509_38353} {RNA1509_38353, RNA815_6313}
18. MligTC455_31370 27 0.55 Mlig455_035805

Neo: -

Age: -

ASIC1 0.957 - - - 0.957 - - Mlig455_035805 {REF} {Length: 3035} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=182.8]} {Human: ENSG00000110881, ASIC1, acid sensing ion channel subunit 1, [Score=60.1, Expect=8e-09]} {Mouse: ENSMUSG00000023017, Asic1, acid-sensing (proton-gated) ion channel 1, [Score=58.5, Expect=2e-08]} {Smed: dd_Smed_v6_16346_0_1, dd_Smed_v6_16346_0_1, [Score=107, Expect=3e-24]} {RNA1310_49983} {RNA815_25991}
19. MligTC455_45665 1443 30.07 Mlig455_011779

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.663

Region-enriched R2: 1.647/0.04427

Regeneration-depleted R6: -3.147
Regeneration-depleted BL: -2.857

0.957 - - - 0.957 - - Mlig455_011779 {REF} {Length: 735} {TRANSSPLICED} {RNA1509_33726} {RNA1310_46610, RNA1509_33726} {RNA1509_33726, RNA815_23273}
20. MligTC455_53413 249 5.2 Mlig455_035022

Neo: -

Age: -

Region-specific R2: 4.451

Region-enriched R2: 3.023/0.00460

RP1 0.957 - - - 0.957 - - Mlig455_035022 {REF} {Length: 5065} {Pfam: PLAT/LH2 domain [PF01477.25, score=155.8]; Doublecortin [PF03607.19, score=103.5]; Embryo-specific protein 3, (ATS3) [PF06232.13, score=22.0]} {Human: ENSG00000104237, RP1, RP1, axonemal microtubule associated, [Score=473, Expect=5e-146]} {Mouse: ENSMUSG00000025900, Rp1, retinitis pigmentosa 1 (human), [Score=454, Expect=1e-136]} {Dmel: FBgn0261387, CG17528, [Score=56.6, Expect=1e-07]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [Score=75.5, Expect=2e-13]} {Smed: dd_Smed_v6_10315_0_2, dd_Smed_v6_10315_0_2, [Score=698, Expect=0.0]} {RNA1509_57003} {RNA1310_2710} {RNA815_13802.1}
21. MligTC455_40270 49 1.03 Mlig455_002977

Neo: -

Age: Down-Up-Down

Region-enriched R2: 7.640/0.00158

AGAP1 0.956 - - - 0.956 - - Mlig455_002977 {REF} {Length: 2591} {Pfam: Ras family [PF00071.24, score=40.1]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=21.9]} {Human: ENSG00000157985, AGAP1, ArfGAP with GTPase domain, ankyrin repeat and PH domain 1, [Score=253, Expect=3e-81]; ENSG00000133612, AGAP3, ArfGAP with GTPase domain, ankyrin repeat and PH domain 3, [Score=243, Expect=2e-77]} {Mouse: ENSMUSG00000055013, Agap1, ArfGAP with GTPase domain, ankyrin repeat and PH domain 1, [Score=253, Expect=2e-77]; ENSMUSG00000023353, Agap3, ArfGAP with GTPase domain, ankyrin repeat and PH domain 3, [Score=243, Expect=2e-77]} {Dmel: FBgn0028509, CenG1A, Centaurin gamma 1A, [Score=251, Expect=7e-76]} {Celegans: WBGene00000566, cnt-2, Arf-GAP with ANK repeat and PH domain-containing protein cnt-2, [Score=205, Expect=2e-59]} {Smed: dd_Smed_v6_4301_0_1, dd_Smed_v6_4301_0_1, [Score=232, Expect=7e-73]} {RNA1509_22773} {RNA1310_2370} {RNA815_11138}
22. MligTC455_14597 7 0.15 Mlig455_017638

Neo: -

Age: -

0.955 - - - 0.955 - - Mlig455_017638 {REF} {Length: 1035} {RNA1310_39570} {RNA815_52309}
23. MligTC455_15837 58 1.21 Mlig455_058574

Neo: -

Age: Up-Down-Up

PLEKHG5 0.954 - - - 0.954 - - Mlig455_058574 {REF} {Length: 3473} {Pfam: RhoGEF domain [PF00621.22, score=89.0]; Pleckstrin homology domain [PF15405.8, score=20.1]} {Human: ENSG00000171680, PLEKHG5, pleckstrin homology and RhoGEF domain containing G5, [Score=191, Expect=1e-49]} {Mouse: ENSMUSG00000039713, Plekhg5, pleckstrin homology domain containing, family G (with RhoGef domain) member 5, [Score=194, Expect=1e-50]} {Dmel: FBgn0261556, CG42674, [Score=147, Expect=1e-35]} {Celegans: WBGene00006476, rhgf-2, RHGF-2; RHo Guanine nucleotide exchange Factor, [RH, Score=142, Expect=3e-34]} {Smed: dd_Smed_v6_10072_0_1, dd_Smed_v6_10072_0_1, [Score=171, Expect=2e-44]} {RNA1310_47096} {RNA815_12538}
24. MligTC455_32612 55 1.15 Mlig455_015630

Neo: -

Age: -

Region-enriched R2: 5.626/0.02523

ARX 0.954 - - - 0.954 - - Mlig455_015630 {REF} {Length: 2012} {Pfam: Homeodomain [PF00046.31, score=83.5]} {Human: ENSG00000004848, ARX, aristaless related homeobox, [RH, Score=134, Expect=1e-34]} {Mouse: ENSMUSG00000035277, Arx, aristaless related homeobox, [RH, Score=133, Expect=1e-34]} {Dmel: FBgn0000061, al, aristaless, [RH, Score=130, Expect=3e-34]} {Celegans: WBGene00044330, alr-1, AristaLess (Drosophila homeodomain) Related, [RH, Score=118, Expect=2e-30]} {Smed: dd_Smed_v6_63359_0_1, dd_Smed_v6_63359_0_1, [Score=119, Expect=3e-33]} {RNA1310_42333.1} {RNA815_48205}
25. MligTC455_33318 175 3.64 Mlig455_069800

Neo: -

Age: Up-Down-Up

CASK 0.953 - - - 0.953 - - Mlig455_069800 {REF} {Length: 4976} {Pfam: Guanylate kinase [PF00625.23, score=193.4]; PDZ domain [PF00595.26, score=56.0]; L27 domain [PF02828.18, score=39.9]; Variant SH3 domain [PF07653.19, score=25.1]; SH3 domain [PF00018.30, score=22.4]; PDZ domain [PF17820.3, score=21.3]; PDZ domain [PF13180.8, score=19.3]} {Human: ENSG00000147044, CASK, calcium/calmodulin dependent serine protein kinase, [RH, Score=619, Expect=0.0]} {Mouse: ENSMUSG00000031012, Cask, calcium/calmodulin-dependent serine protein kinase (MAGUK family), [Score=614, Expect=0.0]} {Dmel: FBgn0013759, CASK, [RH, Score=573, Expect=0.0]} {Celegans: WBGene00002991, lin-2, [RH, Score=535, Expect=2e-178]} {Smed: dd_Smed_v6_7723_0_4, dd_Smed_v6_7723_0_4, [Score=694, Expect=0.0]} {RNA1509_30764} {RNA1310_4720.1} {RNA815_18816}
26. MligTC455_54064 85 1.76 Mlig455_002543, Mlig455_002586

Neo: -

Age: -

Region-enriched R8: 4.573/0.01369

0.953 - - - 0.953 - -

Mlig455_002543 {REF} {Length: 2311} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=32.4]} {RNA1310_11536} {RNA815_6619.1}

Mlig455_002586 {REF} {Length: 2383} {RNA1310_11536} {RNA815_6619.1}
27. MligTC455_12131 23 0.47 Mlig455_013913

Neo: -

Age: -

0.952 - - - 0.952 - - Mlig455_013913 {REF} {Length: 1451} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=38.4]} {Smed: dd_Smed_v6_33525_0_1, dd_Smed_v6_33525_0_1, [Score=115, Expect=4e-30]} {RNA1310_68929} {RNA815_54261}
28. MligTC455_44532 114 2.38 Mlig455_011871

Neo: -

Age: -

0.952 - - 0.952 - - - Mlig455_011871 {REF} {Length: 1178} {TRANSSPLICED} {RNA1509_38790, RNA1509_59200} {RNA1310_25247, RNA1509_59200} {RNA1509_59200, RNA815_24666}
29. MligTC455_35019 168 3.49 Mlig455_046994

Neo: -

Age: -

ASIC4 0.951 - - - 0.951 - - Mlig455_046994 {REF} {Length: 4001} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=101.4]} {Human: ENSG00000072182, ASIC4, acid sensing ion channel subunit family member 4, [Score=76.3, Expect=1e-13]} {Mouse: ENSMUSG00000033007, Asic4, acid-sensing (proton-gated) ion channel family member 4, [Score=76.3, Expect=8e-14]; ENSMUSG00000023017, Asic1, acid-sensing (proton-gated) ion channel 1, [Score=72.8, Expect=8e-13]} {Smed: dd_Smed_v6_15233_0_1, dd_Smed_v6_15233_0_1, [RH, Score=103, Expect=1e-22]} {RNA1509_33816} {RNA1310_3176, RNA1509_33816} {RNA1509_33816, RNA815_12439}
30. MligTC455_38227 131 2.73 Mlig455_049364

Neo: -

Age: Down-Up-Up

Region-enriched R2: 5.468/0.02435

0.951 - - - 0.951 - - Mlig455_049364 {REF} {Length: 726} {RNA1509_22173} {RNA1310_65747} {RNA815_15489}
31. MligTC455_35802 114 2.38 Mlig455_051876, Mlig455_051902, Mlig455_053140

Neo: -

Age: -

CACNA2D1 0.95 - - - 0.950 - -

Mlig455_051876 {REF} {Length: 3144} {Pfam: Neuronal voltage-dependent calcium channel alpha 2acd [PF08473.13, score=89.1]} {Human: ENSG00000153956, CACNA2D1, calcium voltage-gated channel auxiliary subunit alpha2delta 1, [Score=84.7, Expect=2e-16]} {RNA1509_55590} {RNA1310_60852} {RNA815_15380}

Mlig455_051902 {REF} {Length: 4662} {Pfam: VWA N-terminal [PF08399.13, score=90.4]; Neuronal voltage-dependent calcium channel alpha 2acd [PF08473.13, score=87.6]; von Willebrand factor type A domain [PF00092.30, score=38.6]; Cache domain [PF02743.20, score=27.5]; von Willebrand factor type A domain [PF13519.8, score=26.5]} {Human: ENSG00000153956, CACNA2D1, calcium voltage-gated channel auxiliary subunit alpha2delta 1, [RH, Score=326, Expect=8e-94]} {Mouse: ENSMUSG00000040118, Cacna2d1, calcium channel, voltage-dependent, alpha2/delta subunit 1, [RH, Score=326, Expect=7e-94]} {Dmel: FBgn0261041, stj, straightjacket, [Score=229, Expect=7e-61]} {Celegans: WBGene00006772, unc-36, Voltage-dependent calcium channel unc-36, [Score=141, Expect=9e-34]} {Smed: dd_Smed_v6_19048_0_1, dd_Smed_v6_19048_0_1, [Score=153, Expect=1e-37]} {RNA1509_55590} {RNA1310_7325.1, RNA1509_55590} {RNA1509_55590, RNA815_14878}

Mlig455_053140 {REF} {Length: 3265} {Pfam: Neuronal voltage-dependent calcium channel alpha 2acd [PF08473.13, score=87.9]} {Human: ENSG00000153956, CACNA2D1, calcium voltage-gated channel auxiliary subunit alpha2delta 1, [Score=87.0, Expect=8e-17]} {Mouse: ENSMUSG00000021991, Cacna2d3, calcium channel, voltage-dependent, alpha2/delta subunit 3, [Score=50.4, Expect=9e-06]} {RNA1509_55590} {RNA1310_7325.1} {RNA815_14878}
32. MligTC455_36285 232 4.84 Mlig455_049585

Neo: -

Age: -

Region-enriched R2: 2.764/0.02680

SGSM1 0.95 - - - 0.950 - - Mlig455_049585 {REF} {Length: 3668} {Pfam: Rab-GTPase-TBC domain [PF00566.20, score=117.8]; Rab-binding domain (RBD) [PF12068.10, score=107.7]; RUN domain [PF02759.21, score=79.1]} {Human: ENSG00000167037, SGSM1, small G protein signaling modulator 1, [RH, Score=428, Expect=4e-132]} {Mouse: ENSMUSG00000038351, Sgsm2, small G protein signaling modulator 2, [RH, Score=637, Expect=0.0]} {Dmel: FBgn0031116, CG1695, [RH, Score=432, Expect=5e-133]} {Celegans: WBGene00008018, tbc-8, TBC (Tre-2/Bub2/Cdc16) domain family, [RH, Score=421, Expect=2e-131]} {Smed: dd_Smed_v6_12130_0_1, dd_Smed_v6_12130_0_1, [RH, Score=609, Expect=0.0]} {RNA1509_48678} {RNA1310_9224, RNA1509_48678} {RNA1509_48678, RNA815_14977}
33. MligTC455_48848 282 5.87 Mlig455_005151, Mlig455_021613

Neo: -

Age: -

Region-specific R2: 4.764

Region-enriched R2: 5.813/0.00000

SYT3 0.95 - - - 0.950 - -

Mlig455_005151 {REF} {Length: 1574} {Pfam: C2 domain [PF00168.32, score=55.1]} {Human: ENSG00000213023, SYT3, synaptotagmin 3, [Score=68.6, Expect=5e-12]; ENSG00000011347, SYT7, synaptotagmin 7, [Score=67.0, Expect=1e-11]} {Mouse: ENSMUSG00000030731, Syt3, synaptotagmin III, [Score=69.3, Expect=2e-12]} {Dmel: FBgn0261089, Sytalpha, Synaptotagmin alpha, [Score=63.2, Expect=1e-10]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=66.6, Expect=5e-12]} {Smed: dd_Smed_v6_25279_0_1, dd_Smed_v6_25279_0_1, [Score=85.1, Expect=2e-18]} {RNA1310_20857} {RNA815_8396}

Mlig455_021613 {REF} {Length: 1574} {Pfam: C2 domain [PF00168.32, score=55.1]} {Human: ENSG00000213023, SYT3, synaptotagmin 3, [Score=68.6, Expect=5e-12]; ENSG00000011347, SYT7, synaptotagmin 7, [Score=67.0, Expect=1e-11]} {Mouse: ENSMUSG00000030731, Syt3, synaptotagmin III, [Score=69.3, Expect=2e-12]} {Dmel: FBgn0261089, Sytalpha, Synaptotagmin alpha, [Score=63.2, Expect=1e-10]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=66.6, Expect=5e-12]} {Smed: dd_Smed_v6_25279_0_1, dd_Smed_v6_25279_0_1, [Score=85.1, Expect=2e-18]} {RNA1310_20857} {RNA815_8396}
34. MligTC455_51478 66 1.37 Mlig455_057080

Neo: -

Age: -

0.95 - - - 0.950 - - Mlig455_057080 {REF} {Length: 1661} {Pfam: 7tm Chemosensory receptor [PF08395.14, score=33.2]; Trehalose receptor [PF06151.15, score=30.3]} {RNA1310_59684} {RNA815_43381}

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