Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_24088 | 1082 | 22.53 | Mlig455_017398, Mlig455_030918 | Neo: - Age: - Regeneration-downregulated TP: -2.327 Regeneration-depleted TP: -2.327 |
CBS | Mlig455_017398 {REF} {Length: 2236} {TRANSSPLICED} {Pfam: Pyridoxal-phosphate dependent enzyme [PF00291.27, score=216.9]; CBS domain [PF00571.30, score=48.7]} {Human: ENSG00000160200, CBS, cystathionine-beta-synthase, [Score=593, Expect=0.0]; ENSG00000274276, CBSL, cystathionine-beta-synthase like, [Score=593, Expect=0.0]} {Mouse: ENSMUSG00000024039, Cbs, cystathionine beta-synthase, [Score=598, Expect=0.0]} {Dmel: FBgn0031148, Cbs, centrosomin's beautiful sister, [RH, Score=442, Expect=2e-151]} {Celegans: WBGene00013866, cbs-1, Cystathionine Beta-Synthase, [RH, Score=365, Expect=6e-119]} {Smed: dd_Smed_v6_1585_0_1, dd_Smed_v6_1585_0_1, [RH, Score=642, Expect=0.0]} {RNA1509_32341} {RNA1310_10466.1} {RNA815_2644.1} Mlig455_030918 {REF} {Length: 2927} {TRANSSPLICED} {Pfam: Pyridoxal-phosphate dependent enzyme [PF00291.27, score=199.2]; CBS domain [PF00571.30, score=49.2]} {Human: ENSG00000160200, CBS, cystathionine-beta-synthase, [Score=557, Expect=0.0]; ENSG00000274276, CBSL, cystathionine-beta-synthase like, [Score=557, Expect=0.0]} {Mouse: ENSMUSG00000024039, Cbs, cystathionine beta-synthase, [Score=558, Expect=0.0]} {Dmel: FBgn0031148, Cbs, centrosomin's beautiful sister, [Score=409, Expect=9e-139]} {Celegans: WBGene00013866, cbs-1, Cystathionine Beta-Synthase, [Score=335, Expect=4e-108]} {Smed: dd_Smed_v6_1585_0_1, dd_Smed_v6_1585_0_1, [Score=603, Expect=0.0]} {RNA1509_32341} {RNA1310_10466.1} {RNA815_2644.1} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -0.975 | 4.761 | 0.30635 | 0.95517 | |
RegionR2 | 0.197 | 4.761 | 0.64248 | 0.97977 | |
RegionR3 | -0.441 | 4.761 | 0.20591 | 0.74585 | |
RegionR4 | -0.093 | 4.761 | 0.81707 | 1.00000 | |
RegionR5 | 0.262 | 4.761 | 0.38913 | 0.74490 | |
RegionR6 | 0.202 | 4.761 | 0.55293 | 1.00000 | |
RegionR7 | 0.366 | 4.761 | 0.35722 | 0.99386 | |
RegionR8 | 0.482 | 4.761 | 0.31106 | 0.94357 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -2.299 | 4.761 | 0.24137 | 0.96582 | |
RegenerationR2 | -0.328 | 4.761 | 0.35777 | 0.78759 | |
RegenerationR3 | 0.25 | 4.761 | 0.53765 | 0.87602 | |
RegenerationR4 | -0.365 | 4.761 | 0.36468 | 0.78998 | |
RegenerationR5 | -0.842 | 4.761 | 0.02503 | 0.26943 | |
RegenerationR6 | -0.1 | 4.761 | 0.79296 | 0.97366 | |
RegenerationBL | 0.427 | 4.761 | 0.27645 | 0.63667 | |
RegenerationTP | -2.327 | 4.761 | 0.00004 | 0.00654 | Specific for TP: -2.327 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_24088 | 1082 | 22.53 | Mlig455_017398, Mlig455_030918 | Neo: - Age: - Regeneration-downregulated TP: -2.327 Regeneration-depleted TP: -2.327 |
CBS | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_017398 {REF} {Length: 2236} {TRANSSPLICED} {Pfam: Pyridoxal-phosphate dependent enzyme [PF00291.27, score=216.9]; CBS domain [PF00571.30, score=48.7]} {Human: ENSG00000160200, CBS, cystathionine-beta-synthase, [Score=593, Expect=0.0]; ENSG00000274276, CBSL, cystathionine-beta-synthase like, [Score=593, Expect=0.0]} {Mouse: ENSMUSG00000024039, Cbs, cystathionine beta-synthase, [Score=598, Expect=0.0]} {Dmel: FBgn0031148, Cbs, centrosomin's beautiful sister, [RH, Score=442, Expect=2e-151]} {Celegans: WBGene00013866, cbs-1, Cystathionine Beta-Synthase, [RH, Score=365, Expect=6e-119]} {Smed: dd_Smed_v6_1585_0_1, dd_Smed_v6_1585_0_1, [RH, Score=642, Expect=0.0]} {RNA1509_32341} {RNA1310_10466.1} {RNA815_2644.1} Mlig455_030918 {REF} {Length: 2927} {TRANSSPLICED} {Pfam: Pyridoxal-phosphate dependent enzyme [PF00291.27, score=199.2]; CBS domain [PF00571.30, score=49.2]} {Human: ENSG00000160200, CBS, cystathionine-beta-synthase, [Score=557, Expect=0.0]; ENSG00000274276, CBSL, cystathionine-beta-synthase like, [Score=557, Expect=0.0]} {Mouse: ENSMUSG00000024039, Cbs, cystathionine beta-synthase, [Score=558, Expect=0.0]} {Dmel: FBgn0031148, Cbs, centrosomin's beautiful sister, [Score=409, Expect=9e-139]} {Celegans: WBGene00013866, cbs-1, Cystathionine Beta-Synthase, [Score=335, Expect=4e-108]} {Smed: dd_Smed_v6_1585_0_1, dd_Smed_v6_1585_0_1, [Score=603, Expect=0.0]} {RNA1509_32341} {RNA1310_10466.1} {RNA815_2644.1} |
2. | MligTC455_24087 | 548 | 11.41 | Mlig455_017476 | Neo: - Age: - |
CBSL | 5.649 | 0.968 | 0.870 | 0.974 | 0.986 | 0.957 | 0.894 | Mlig455_017476 {REF} {Length: 2130} {TRANSSPLICED} {Pfam: Pyridoxal-phosphate dependent enzyme [PF00291.27, score=219.8]; CBS domain [PF00571.30, score=48.5]} {Human: ENSG00000274276, CBSL, cystathionine-beta-synthase like, [RH, Score=619, Expect=0.0]; ENSG00000160200, CBS, cystathionine-beta-synthase, [RH, Score=619, Expect=0.0]} {Mouse: ENSMUSG00000024039, Cbs, cystathionine beta-synthase, [RH, Score=622, Expect=0.0]} {Dmel: FBgn0031148, Cbs, centrosomin's beautiful sister, [RH, Score=452, Expect=9e-155]} {Celegans: WBGene00013866, cbs-1, Cystathionine Beta-Synthase, [RH, Score=370, Expect=9e-121]} {Smed: dd_Smed_v6_1585_0_1, dd_Smed_v6_1585_0_1, [RH, Score=659, Expect=0.0]} {RNA1509_32341} {RNA1310_10466.1} {RNA815_2644.1} |
3. | MligTC455_51681 | 762 | 15.87 | Mlig455_009904 | Neo: - Age: - Regeneration-upregulated BL: 1.809 Regeneration-enriched BL: 1.809 |
YBX3 | 2.579 | - | - | - | 0.806 | 0.819 | 0.954 | Mlig455_009904 {REF} {Length: 3925} {Pfam: 'Cold-shock' DNA-binding domain [PF00313.24, score=92.6]} {Human: ENSG00000060138, YBX3, Y-box binding protein 3, [RH, Score=161, Expect=2e-47]; ENSG00000065978, YBX1, Y-box binding protein 1, [RH, Score=157, Expect=2e-45]; ENSG00000006047, YBX2, Y-box binding protein 2, [RH, Score=153, Expect=2e-43]} {Mouse: ENSMUSG00000030189, Ybx3, Y box protein 3, [RH, Score=162, Expect=8e-48]; ENSMUSG00000028639, Ybx1, Y box protein 1, [RH, Score=157, Expect=1e-45]} {Dmel: FBgn0022959, yps, ypsilon schachtel, [RH, Score=154, Expect=2e-44]} {Celegans: WBGene00000472, cey-1, C. Elegans Y-box, [RH, Score=146, Expect=4e-43]} {Smed: dd_Smed_v6_25570_0_1, dd_Smed_v6_25570_0_1, [Score=162, Expect=1e-47]} {RNA1509_14234, RNA1509_43002} {RNA1310_16756, RNA1509_14234} {RNA1509_14234, RNA815_19171.1} |
4. | MligTC455_26129 | 210 | 4.36 | Mlig455_009377 | Neo: - Age: - |
1.763 | - | - | 0.813 | - | 0.950 | - | Mlig455_009377 {REF} {Length: 4183} {tRNA: Val(AAC),pseudo, score=28.6} {Pfam: Cysteine rich repeat [PF02363.21, score=20.8]} {Mouse: ENSMUSG00000024246, Thumpd2, THUMP domain containing 2, [Score=81.3, Expect=2e-16]} {Celegans: WBGene00018026, F35A5.4, [Score=73.9, Expect=2e-14]} {RNA1509_46710} {RNA1310_29730} {RNA815_15860} | |
5. | MligTC455_30512 | 296 | 6.16 | Mlig455_057485 | Neo: - Age: - |
CPNE8 | 1.682 | 0.704 | - | - | - | 0.978 | - | Mlig455_057485 {REF} {Length: 5002} {TRANSSPLICED} {Pfam: Copine [PF07002.18, score=261.8]; C2 domain [PF00168.32, score=88.0]; vWA found in TerF C terminus [PF10138.11, score=30.8]} {Human: ENSG00000139117, CPNE8, copine 8, [RH, Score=491, Expect=2e-167]; ENSG00000124772, CPNE5, copine 5, [RH, Score=475, Expect=5e-161]; ENSG00000085719, CPNE3, copine 3, [RH, Score=473, Expect=8e-161]; ENSG00000214078, CPNE1, copine 1, [RH, Score=467, Expect=2e-158]} {Mouse: ENSMUSG00000052560, Cpne8, copine VIII, [RH, Score=489, Expect=8e-167]; ENSMUSG00000024008, Cpne5, copine V, [RH, Score=480, Expect=5e-163]; ENSMUSG00000028228, Cpne3, copine III, [RH, Score=479, Expect=1e-163]} {Celegans: WBGene00012128, nra-1, Nicotinic receptor-associated protein 1, [RH, Score=383, Expect=3e-125]} {Smed: dd_Smed_v6_2149_0_1, dd_Smed_v6_2149_0_1, [RH, Score=544, Expect=0.0]} {RNA1509_30376} {RNA1310_21877.1} {RNA815_8974} |
6. | MligTC455_23447 | 435 | 9.06 | Mlig455_035033 | Neo: - Age: Up-Down-Down |
CC2D2A | 0.966 | - | - | - | 0.966 | - | - | Mlig455_035033 {REF} {Length: 5525} {TRANSSPLICED} {Pfam: CC2D2A N-terminal C2 domain [PF15625.8, score=58.2]; C2 domain [PF00168.32, score=36.8]; Family of unknown function (DUF5523) [PF17661.3, score=33.5]} {Human: ENSG00000048342, CC2D2A, coiled-coil and C2 domain containing 2A, [RH, Score=397, Expect=1e-113]} {Mouse: ENSMUSG00000039765, Cc2d2a, coiled-coil and C2 domain containing 2A, [RH, Score=394, Expect=9e-113]} {Dmel: FBgn0263113, Cc2d2a, Coiled-coil and C2 domain containing 2A, [RH, Score=117, Expect=4e-26]} {Celegans: WBGene00010642, mks-6, MecKel-Gruber Syndrome (MKS) homolog, [RH, Score=88.6, Expect=3e-17]} {Smed: dd_Smed_v6_11189_0_1, dd_Smed_v6_11189_0_1, [RH, Score=460, Expect=9e-136]} {RNA1509_46603} {RNA1310_6995.1} {RNA815_316.1} |
7. | MligTC455_30427 | 370 | 7.7 | Mlig455_014862, Mlig455_014902, Mlig455_014903, Mlig455_024518, Mlig455_052526 | Neo: - Age: Up-Down-Up |
0.963 | - | - | - | 0.963 | - | - | Mlig455_014862 {REF} {Length: 4961} {Pfam: Pentapeptide repeats (9 copies) [PF13599.8, score=39.6]} {RNA1509_13222} {RNA1310_59923} {RNA815_11419.1} Mlig455_014902 {REF} {Length: 149} {Pfam: NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial [PF15880.7, score=23.5]} {RNA1509_57968} Mlig455_014903 {REF} {Length: 149} {Pfam: NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial [PF15880.7, score=23.5]} {RNA1509_57968} Mlig455_024518 {REF} {Length: 4185} {NoTransDecoderORF} {RNA1509_3398} {RNA1310_24716.1} {RNA815_11419.1} Mlig455_052526 {REF} {Length: 804} {NoTransDecoderORF} {RNA1509_25657} {RNA1310_41739} {RNA815_34613} |
|
8. | MligTC455_16427 | 1100 | 22.91 | Mlig455_004703, Mlig455_004776, Mlig455_067254 | Neo: - Age: - Regeneration-upregulated BL: 1.571 Regeneration-enriched BL: 1.571 |
PIWIL1 | 0.958 | - | - | - | - | 0.958 | - | Mlig455_004703 {REF} {Length: 678} {NoTransDecoderORF} {RNA1509_38018} {RNA1310_63004} {RNA815_29902} Mlig455_004776 {REF} {Length: 4091} {TRANSSPLICED} {Pfam: Piwi domain [PF02171.19, score=260.5]; PAZ domain [PF02170.24, score=99.8]; Argonaute linker 1 domain [PF08699.12, score=31.3]} {Human: ENSG00000125207, PIWIL1, piwi like RNA-mediated gene silencing 1, [RH, Score=563, Expect=0.0]; ENSG00000275051, PIWIL1, piwi like RNA-mediated gene silencing 1, [RH, Score=563, Expect=0.0]} {Mouse: ENSMUSG00000029423, Piwil1, piwi-like RNA-mediated gene silencing 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0250816, AGO3, Argonaute 3, [RH, Score=468, Expect=1e-151]} {Celegans: WBGene00004178, prg-1, Piwi-like protein, [RH, Score=415, Expect=9e-132]} {Smed: dd_Smed_v6_1258_0_1, dd_Smed_v6_1258_0_1, [Score=488, Expect=5e-158]} {RNA1509_12087, RNA1509_32406, RNA1509_3572, RNA1509_47657, RNA1509_56648} {RNA1310_5159, RNA1509_12087, RNA1509_32406, RNA1509_3572, RNA1509_47657, RNA1509_56648} {RNA1509_12087, RNA1509_32406, RNA1509_3572, RNA1509_47657, RNA1509_56648, RNA815_1776} Mlig455_067254 {REF} {Length: 725} {Pfam: Piwi domain [PF02171.19, score=171.8]} {Human: ENSG00000275051, PIWIL1, piwi like RNA-mediated gene silencing 1, [Score=192, Expect=9e-56]; ENSG00000125207, PIWIL1, piwi like RNA-mediated gene silencing 1, [Score=192, Expect=9e-56]} {Mouse: ENSMUSG00000029423, Piwil1, piwi-like RNA-mediated gene silencing 1, [Score=189, Expect=4e-55]} {Dmel: FBgn0250816, AGO3, Argonaute 3, [Score=190, Expect=2e-55]} {Celegans: WBGene00004179, prg-2, Piwi-like protein, [Score=165, Expect=5e-47]} {Smed: dd_Smed_v6_756_0_1, dd_Smed_v6_756_0_1, [Score=174, Expect=5e-50]} {RNA1509_56648} {RNA1310_5159} {RNA815_1776} |
9. | MligTC455_27513 | 326 | 6.8 | Mlig455_027937 | Neo: - Age: logFC(26M/2M)=-0.593 |
MAP3K4 | 0.955 | - | - | - | 0.955 | - | - | Mlig455_027937 {REF} {Length: 2685} {Pfam: Protein kinase domain [PF00069.27, score=165.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=123.4]; Ankyrin repeats (3 copies) [PF12796.9, score=78.4]; Ankyrin repeats (many copies) [PF13637.8, score=58.3]; Ankyrin repeat [PF13606.8, score=56.2]; Ankyrin repeats (many copies) [PF13857.8, score=46.5]; Ankyrin repeat [PF00023.32, score=40.7]; Fungal protein kinase [PF17667.3, score=27.5]} {Human: ENSG00000085511, MAP3K4, mitogen-activated protein kinase kinase kinase 4, [Score=132, Expect=4e-31]} {Mouse: ENSMUSG00000014426, Map3k4, mitogen-activated protein kinase kinase kinase 4, [Score=128, Expect=6e-30]; ENSMUSG00000028862, Map3k6, mitogen-activated protein kinase kinase kinase 6, [Score=123, Expect=2e-28]; ENSMUSG00000031303, Map3k15, mitogen-activated protein kinase kinase kinase 15, [Score=122, Expect=3e-28]} {Dmel: FBgn0024329, Mekk1, [Score=126, Expect=2e-29]} {Celegans: WBGene00003472, mtk-1, MTK1/MEKK4 homolog, [Score=137, Expect=4e-33]} {Smed: dd_Smed_v6_4849_0_1, dd_Smed_v6_4849_0_1, [Score=112, Expect=2e-25]} {RNA1509_27731} {RNA1310_10050} {RNA815_9449.1} |