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Results for MligTC455_25252

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_25252 56 1.17 Mlig455_041099

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.304

Mlig455_041099 {REF} {Length: 4133} {Pfam: Protein of unknown function (DUF1722) [PF08349.13, score=20.9]} {RNA1509_30687} {RNA1310_3877.1, RNA1509_30687} {RNA1509_30687, RNA815_1645}

Cumulative graph for MligTC455_25252

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -2.066 1.555 0.72126 1.00000
RegionR2 0.546 1.555 0.69221 1.00000
RegionR3 -0.436 1.555 0.95762 1.00000
RegionR4 0.732 1.555 0.54647 0.86798
RegionR5 -0.826 1.555 0.98433 1.00000
RegionR6 -0.193 1.555 0.92131 1.00000
RegionR7 0.451 1.555 0.74613 1.00000
RegionR8 1.791 1.555 0.34468 0.97797

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -2.135 1.555 0.99986 1.00000
RegenerationR2 0.801 1.555 0.19567 0.64023
RegenerationR3 0.25 1.555 0.83336 0.99165
RegenerationR4 -0.745 1.555 0.41168 0.82159
RegenerationR5 -0.195 1.555 0.82047 0.99446
RegenerationR6 -2.102 1.555 0.07676 0.34626
RegenerationBL -1.781 1.555 0.22207 0.57032
RegenerationTP -1.977 1.555 0.23020 0.67528


Genes with expression patterns similar to MligTC455_25252

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_25252 56 1.17 Mlig455_041099

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.304

5 - 1.000 1.000 1.000 1.000 1.000 Mlig455_041099 {REF} {Length: 4133} {Pfam: Protein of unknown function (DUF1722) [PF08349.13, score=20.9]} {RNA1509_30687} {RNA1310_3877.1, RNA1509_30687} {RNA1509_30687, RNA815_1645}
2. MligTC455_47160 747 15.56 Mlig455_021750

Neo: -

Age: logFC(26M/2M)=-0.246

FAM184A 3.082 - - 0.718 0.714 0.950 0.700 Mlig455_021750 {REF} {Length: 3705} {Pfam: Family with sequence similarity 184, A and B [PF15665.7, score=130.1]} {Human: ENSG00000111879, FAM184A, family with sequence similarity 184 member A, [RH, Score=340, Expect=5e-99]} {Mouse: ENSMUSG00000019856, Fam184a, family with sequence similarity 184, member A, [RH, Score=308, Expect=7e-88]} {Celegans: WBGene00001328, epi-1, Laminin-like protein epi-1, [Score=60.8, Expect=5e-09]} {Smed: dd_Smed_v6_16975_0_1, dd_Smed_v6_16975_0_1, [RH, Score=264, Expect=3e-73]} {RNA1509_5806} {RNA1310_3258.1, RNA1509_5806} {RNA1509_5806, RNA815_936}
3. MligTC455_16908 161 3.35 Mlig455_046916

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.397

Region-enriched R2: 2.938/0.02849

SLC17A6 2.662 - - - 0.936 0.972 0.754 Mlig455_046916 {REF} {Length: 3198} {Pfam: Major Facilitator Superfamily [PF07690.18, score=172.0]; Uncharacterised MFS-type transporter YbfB [PF06779.16, score=19.6]} {Human: ENSG00000091664, SLC17A6, solute carrier family 17 member 6, [RH, Score=548, Expect=0.0]; ENSG00000179520, SLC17A8, solute carrier family 17 member 8, [RH, Score=542, Expect=0.0]; ENSG00000104888, SLC17A7, solute carrier family 17 member 7, [RH, Score=536, Expect=0.0]} {Mouse: ENSMUSG00000019935, Slc17a8, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8, [RH, Score=551, Expect=0.0]; ENSMUSG00000030500, Slc17a6, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6, [RH, Score=547, Expect=0.0]; ENSMUSG00000070570, Slc17a7, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, [RH, Score=543, Expect=0.0]} {Dmel: FBgn0031424, VGlut, Vesicular glutamate transporter, [Score=482, Expect=6e-163]} {Celegans: WBGene00001135, eat-4, Probable vesicular glutamate transporter eat-4, [RH, Score=479, Expect=7e-163]} {Smed: dd_Smed_v6_10192_0_1, dd_Smed_v6_10192_0_1, [RH, Score=591, Expect=0.0]} {RNA1509_38152} {RNA1310_23072, RNA1509_38152} {RNA1509_38152, RNA815_14894}
4. MligTC455_33831 198 4.13 Mlig455_029369

Neo: -

Age: -

Region-enriched R2: 3.223/0.02852

Regeneration-downregulated TP: -7.340

Regeneration-depleted TP: -7.340

GLRA3 2.657 - - - 0.952 0.944 0.761 Mlig455_029369 {REF} {Length: 3665} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=149.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=84.5]} {Human: ENSG00000145451, GLRA3, glycine receptor alpha 3, [Score=257, Expect=5e-80]; ENSG00000145888, GLRA1, glycine receptor alpha 1, [Score=253, Expect=2e-78]; ENSG00000101958, GLRA2, glycine receptor alpha 2, [Score=250, Expect=4e-77]} {Mouse: ENSMUSG00000038257, Glra3, glycine receptor, alpha 3 subunit, [Score=251, Expect=2e-77]; ENSMUSG00000018589, Glra2, glycine receptor, alpha 2 subunit, [Score=249, Expect=3e-77]; ENSMUSG00000000263, Glra1, glycine receptor, alpha 1 subunit, [Score=248, Expect=1e-76]; ENSMUSG00000018595, Glra4, glycine receptor, alpha 4 subunit, [Score=243, Expect=1e-74]} {Dmel: FBgn0024963, GluClalpha, [Score=253, Expect=2e-78]} {Celegans: WBGene00000233, avr-15, GluClalpha2B protein, [Score=259, Expect=5e-81]} {Smed: dd_Smed_v6_11342_0_1, dd_Smed_v6_11342_0_1, [RH, Score=480, Expect=2e-167]} {RNA1509_35986} {RNA1310_35528} {RNA815_11925.1}
5. MligTC455_03841 920 19.16 Mlig455_018790, Mlig455_048140

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.474

Region-enriched R2: 5.915/0.00081

NKX2-1, NKX2-4 2.638 - - 0.875 0.807 0.956 -

Mlig455_018790 {REF} {Length: 2203} {Pfam: Homeodomain [PF00046.31, score=72.7]} {Human: ENSG00000136352, NKX2-1, NK2 homeobox 1, [RH, Score=145, Expect=2e-39]; ENSG00000125816, NKX2-4, NK2 homeobox 4, [RH, Score=145, Expect=2e-39]} {Mouse: ENSMUSG00000001496, Nkx2-1, NK2 homeobox 1, [RH, Score=145, Expect=2e-39]} {Dmel: FBgn0028993, scro, scarecrow, [RH, Score=166, Expect=8e-47]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [RH, Score=134, Expect=2e-36]} {Smed: dd_Smed_v6_6729_0_1, dd_Smed_v6_6729_0_1, [RH, Score=191, Expect=1e-57]} {RNA1509_12761} {RNA1310_13401} {RNA815_21584}

Mlig455_048140 {REF} {Length: 2218} {Pfam: Homeodomain [PF00046.31, score=72.5]} {Human: ENSG00000125816, NKX2-4, NK2 homeobox 4, [RH, Score=145, Expect=3e-39]; ENSG00000136352, NKX2-1, NK2 homeobox 1, [RH, Score=145, Expect=7e-39]} {Mouse: ENSMUSG00000001496, Nkx2-1, NK2 homeobox 1, [RH, Score=144, Expect=6e-39]} {Dmel: FBgn0028993, scro, scarecrow, [RH, Score=166, Expect=2e-46]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [RH, Score=136, Expect=1e-36]} {Smed: dd_Smed_v6_6729_0_1, dd_Smed_v6_6729_0_1, [RH, Score=193, Expect=1e-57]} {RNA1509_12761} {RNA1310_13401, RNA1509_12761} {RNA1509_12761, RNA815_21584}
6. MligTC455_36667 84 1.75 Mlig455_016177

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.440

Region-enriched R2: 4.490/0.00556
Region-enriched R7: 4.016/0.01613

2.631 - - - 0.916 0.958 0.757 Mlig455_016177 {REF} {Length: 3035} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=47.6]; Immunoglobulin domain [PF13927.8, score=47.0]; Immunoglobulin domain [PF00047.27, score=32.1]; Immunoglobulin domain [PF13895.8, score=27.4]; Natural killer cell receptor 2B4 [PF11465.10, score=26.4]; Immunoglobulin V-set domain [PF07686.19, score=23.5]} {Dmel: FBgn0259245, DIP-beta, Dpr-interacting protein beta, [Score=58.9, Expect=3e-09]} {Celegans: WBGene00006985, zig-8, Zwei Ig domain protein zig-8, [RH, Score=57.0, Expect=4e-09]} {Smed: dd_Smed_v6_21969_0_1, dd_Smed_v6_21969_0_1, [Score=72.0, Expect=6e-14]} {RNA1509_49618} {RNA1310_15195} {RNA815_58259}
7. MligTC455_40657 90 1.87 Mlig455_040779

Neo: -

Age: -

CLIP2 2.629 - - 0.843 0.818 0.968 - Mlig455_040779 {REF} {Length: 2164} {Pfam: CAP-Gly domain [PF01302.27, score=60.7]} {Human: ENSG00000106665, CLIP2, CAP-Gly domain containing linker protein 2, [Score=61.6, Expect=2e-09]} {Mouse: ENSMUSG00000063146, Clip2, CAP-GLY domain containing linker protein 2, [Score=62.0, Expect=1e-09]} {Dmel: FBgn0036882, CG9279, [Score=54.7, Expect=1e-07]} {Smed: dd_Smed_v6_12985_0_1, dd_Smed_v6_12985_0_1, [Score=56.2, Expect=2e-08]} {RNA1310_20676} {RNA815_40746}
8. MligTC455_23544 169 3.53 Mlig455_021925

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.394/0.00033

DDR2 2.624 - - - 0.957 0.915 0.752 Mlig455_021925 {REF} {Length: 4813} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=205.5]; Protein kinase domain [PF00069.27, score=103.7]; F5/8 type C domain [PF00754.27, score=57.5]} {Human: ENSG00000162733, DDR2, discoidin domain receptor tyrosine kinase 2, [Score=249, Expect=1e-68]} {Mouse: ENSMUSG00000026674, Ddr2, discoidin domain receptor family, member 2, [Score=251, Expect=1e-69]} {Dmel: FBgn0053531, Ddr, Discoidin domain receptor, [Score=238, Expect=3e-64]} {Celegans: WBGene00017381, svh-4, Discoidin domain-containing receptor tyrosine kinase B, [Score=176, Expect=3e-45]} {Smed: dd_Smed_v6_22332_0_1, dd_Smed_v6_22332_0_1, [Score=187, Expect=2e-48]} {RNA1509_46581} {RNA1310_21361} {RNA815_21661}
9. MligTC455_13975 63 1.31 Mlig455_070810

Neo: -

Age: -

Region-enriched R2: 7.513/0.00519

2.614 - - - 0.907 0.982 0.725 Mlig455_070810 {REF} {Length: 1542} {Pfam: Otopetrin [PF03189.15, score=108.9]} {Dmel: FBgn0031514, CG3332, [Score=74.3, Expect=3e-14]} {Celegans: WBGene00015035, otpl-1, OToPetrin-Like, [Score=47.8, Expect=9e-06]} {Smed: dd_Smed_v6_13612_0_3, dd_Smed_v6_13612_0_3, [Score=119, Expect=2e-29]} {RNA1310_93602} {RNA815_48323}
10. MligTC455_45770 227 4.74 Mlig455_059517

Neo: -

Age: Down-Up-Up

2.612 - - - 0.865 0.994 0.753 Mlig455_059517 {REF} {Length: 3260} {Pfam: NACHT domain [PF05729.14, score=31.8]; AAA ATPase domain [PF13191.8, score=23.9]} {Smed: dd_Smed_v6_9074_0_1, dd_Smed_v6_9074_0_1, [Score=143, Expect=4e-35]} {RNA1509_44893} {RNA1310_38241, RNA1509_44893} {RNA1509_44893, RNA815_33748}
11. MligTC455_13612 95 1.98 Mlig455_060964

Neo: -

Age: -

2.539 - - - 0.863 0.951 0.725 Mlig455_060964 {REF} {Length: 2501} {Pfam: NPH3 family [PF03000.16, score=44.6]; BTB/POZ domain [PF00651.33, score=25.4]} {Smed: dd_Smed_v6_8081_0_1, dd_Smed_v6_8081_0_1, [Score=160, Expect=4e-42]} {RNA1310_11638} {RNA815_12936}
12. MligTC455_39064 110 2.28 Mlig455_000222, Mlig455_058480

Neo: Irradiation

Age: -

Region-enriched R2: 5.418/0.00017

OSBPL1A 2.532 - - - 0.958 0.855 0.719

Mlig455_000222 {REF} {Length: 2113} {Pfam: Oxysterol-binding protein [PF01237.20, score=414.5]} {Human: ENSG00000141447, OSBPL1A, oxysterol binding protein like 1A, [RH, Score=375, Expect=2e-116]; ENSG00000130703, OSBPL2, oxysterol binding protein like 2, [RH, Score=357, Expect=8e-115]} {Mouse: ENSMUSG00000044252, Osbpl1a, oxysterol binding protein-like 1A, [RH, Score=378, Expect=4e-122]; ENSMUSG00000039050, Osbpl2, oxysterol binding protein-like 2, [RH, Score=367, Expect=6e-119]} {Dmel: FBgn0034951, CG3860, [RH, Score=409, Expect=1e-135]} {Celegans: WBGene00008832, obr-2, Oxysterol Binding protein (OSBP) Related, [RH, Score=239, Expect=3e-71]} {Smed: dd_Smed_v6_3179_0_1, dd_Smed_v6_3179_0_1, [RH, Score=385, Expect=3e-126]} {RNA1509_29630} {RNA1310_38654} {RNA815_7740}

Mlig455_058480 {REF} {Length: 2888} {TRANSSPLICED} {Pfam: Oxysterol-binding protein [PF01237.20, score=414.5]} {Human: ENSG00000141447, OSBPL1A, oxysterol binding protein like 1A, [RH, Score=375, Expect=2e-116]; ENSG00000130703, OSBPL2, oxysterol binding protein like 2, [RH, Score=357, Expect=8e-115]} {Mouse: ENSMUSG00000044252, Osbpl1a, oxysterol binding protein-like 1A, [RH, Score=378, Expect=4e-122]; ENSMUSG00000039050, Osbpl2, oxysterol binding protein-like 2, [RH, Score=367, Expect=6e-119]} {Dmel: FBgn0034951, CG3860, [RH, Score=409, Expect=1e-135]} {Celegans: WBGene00008832, obr-2, Oxysterol Binding protein (OSBP) Related, [RH, Score=239, Expect=3e-71]} {Smed: dd_Smed_v6_3179_0_1, dd_Smed_v6_3179_0_1, [RH, Score=385, Expect=3e-126]} {RNA1509_29630} {RNA1310_38654} {RNA815_26411}
13. MligTC455_12277 22 0.46 Mlig455_025521

Neo: -

Age: Down-Up-Down

CASP3 2.51 - - - 0.950 0.858 0.702 Mlig455_025521 {REF} {Length: 4174} {Pfam: Protein kinase domain [PF00069.27, score=194.8]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=181.9]; Caspase domain [PF00656.24, score=110.6]} {Human: ENSG00000164305, CASP3, caspase 3, [Score=135, Expect=8e-35]; ENSG00000138794, CASP6, caspase 6, [Score=129, Expect=2e-32]} {Mouse: ENSMUSG00000031628, Casp3, caspase 3, [Score=132, Expect=6e-34]; ENSMUSG00000028914, Casp9, caspase 9, [Score=129, Expect=4e-31]} {Dmel: FBgn0010501, Dcp-1, Death caspase-1, [Score=113, Expect=5e-27]} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=130, Expect=2e-33]} {Smed: dd_Smed_v6_10708_0_1, dd_Smed_v6_10708_0_1, [RH, Score=124, Expect=4e-30]} {RNA1509_16483} {RNA1310_10829} {RNA815_3681.1}
14. MligTC455_42021 455 9.48 Mlig455_023402, Mlig455_045563

Neo: -

Age: -

LOXHD1 2.508 - - 0.738 - 0.954 0.816

Mlig455_023402 {REF} {Length: 2349} {TRANSSPLICED} {Pfam: PLAT/LH2 domain [PF01477.25, score=48.7]} {Human: ENSG00000167210, LOXHD1, lipoxygenase homology domains 1, [Score=68.6, Expect=1e-11]} {Mouse: ENSMUSG00000032818, Loxhd1, lipoxygenase homology domains 1, [Score=67.8, Expect=1e-11]} {Smed: dd_Smed_v6_39713_0_1, dd_Smed_v6_39713_0_1, [Score=79.3, Expect=8e-16]} {RNA1509_24550, RNA1509_37714} {RNA1310_21907, RNA1509_24550, RNA1509_37714} {RNA1509_24550, RNA1509_37714, RNA815_9183}

Mlig455_045563 {REF} {Length: 2379} {TRANSSPLICED} {Pfam: PLAT/LH2 domain [PF01477.25, score=46.8]} {Human: ENSG00000167210, LOXHD1, lipoxygenase homology domains 1, [Score=63.5, Expect=5e-10]} {Mouse: ENSMUSG00000032818, Loxhd1, lipoxygenase homology domains 1, [Score=68.9, Expect=8e-12]} {Smed: dd_Smed_v6_39713_0_1, dd_Smed_v6_39713_0_1, [Score=76.3, Expect=1e-14]} {RNA1509_24550} {RNA1310_21907} {RNA815_9183}
15. MligTC455_15467 225 4.69 Mlig455_000546

Neo: -

Age: Down-Up-Up

Region-specific R2: 6.857

Region-enriched R2: 5.997/0.00105

2.496 - - - 0.956 0.735 0.805 Mlig455_000546 {REF} {Length: 844} {Pfam: Pancreatic hormone peptide [PF00159.20, score=42.9]} {Smed: dd_Smed_v6_16946_0_1, dd_Smed_v6_16946_0_1, [Score=39.7, Expect=1e-05]} {RNA1310_53697} {RNA815_26198}
16. MligTC455_42035 64 1.34 Mlig455_005576

Neo: -

Age: -

LGR4 2.493 - - 0.807 0.726 0.960 - Mlig455_005576 {REF} {Length: 2995} {Pfam: Leucine rich repeat [PF13855.8, score=100.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=48.4]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=38.5]; Leucine Rich Repeat [PF00560.35, score=22.1]; Leucine-rich repeat [PF14580.8, score=18.6]} {Human: ENSG00000205213, LGR4, leucine rich repeat containing G protein-coupled receptor 4, [Score=68.6, Expect=1e-11]; ENSG00000198799, LRIG2, leucine rich repeats and immunoglobulin like domains 2, [Score=68.2, Expect=1e-11]; ENSG00000099769, IGFALS, insulin like growth factor binding protein acid labile subunit, [Score=68.2, Expect=1e-11]; ENSG00000172061, LRRC15, leucine rich repeat containing 15, [Score=67.8, Expect=2e-11]; ENSG00000011465, DCN, decorin, [Score=66.2, Expect=2e-11]; ENSG00000186105, LRRC70, leucine rich repeat containing 70, [Score=66.2, Expect=5e-11]} {Mouse: ENSMUSG00000050199, Lgr4, leucine-rich repeat-containing G protein-coupled receptor 4, [Score=68.9, Expect=6e-12]; ENSMUSG00000032913, Lrig2, leucine-rich repeats and immunoglobulin-like domains 2, [Score=65.9, Expect=5e-11]; ENSMUSG00000052316, Lrrc15, leucine rich repeat containing 15, [Score=65.5, Expect=5e-11]} {Dmel: FBgn0003255, rk, rickets, [Score=65.1, Expect=7e-11]} {Celegans: WBGene00019351, lron-7, ELRR (Extracellular Leucine-Rich Repeat) ONly, [Score=61.2, Expect=6e-10]} {Smed: dd_Smed_v6_19180_0_1, dd_Smed_v6_19180_0_1, [Score=47.4, Expect=1e-05]} {RNA1310_20141.1} {RNA815_7925.1}
17. MligTC455_53843 1448 30.17 Mlig455_048664

Neo: -

Age: logFC(26M/2M)=0.488

2.412 - - - 0.724 0.973 0.715 Mlig455_048664 {REF} {Length: 1660} {RNA1509_15580} {RNA1310_24090, RNA1509_15580} {RNA1509_15580, RNA815_10676.2}
18. MligTC455_50660 81 1.7 Mlig455_019591

Neo: -

Age: -

SLC9B2 2.409 - - - 0.973 0.704 0.732 Mlig455_019591 {REF} {Length: 2686} {Pfam: Sodium/hydrogen exchanger family [PF00999.23, score=30.0]} {Human: ENSG00000164038, SLC9B2, solute carrier family 9 member B2, [Score=124, Expect=1e-31]} {Mouse: ENSMUSG00000037994, Slc9b2, solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2, [Score=116, Expect=1e-28]; ENSMUSG00000050150, Slc9b1, solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1, [Score=112, Expect=2e-27]} {Dmel: FBgn0263390, Nha2, Na[+]/H[+] hydrogen antiporter 2, [Score=113, Expect=1e-27]} {Celegans: WBGene00009618, F41E7.2, [Score=70.9, Expect=2e-13]} {Smed: dd_Smed_v6_7736_0_1, dd_Smed_v6_7736_0_1, [Score=148, Expect=1e-43]} {RNA1509_34461} {RNA1310_39553.1} {RNA815_32589}
19. MligTC455_23445 11181 232.93 Mlig455_016960, Mlig455_059585, Mlig455_069851

Neo: -

Age: logFC(26M/2M)=-0.114

MUT 2.392 - - 0.721 - 0.962 0.709

Mlig455_016960 {REF} {Length: 3018} {TRANSSPLICED} {Pfam: Methylmalonyl-CoA mutase [PF01642.24, score=726.3]; B12 binding domain [PF02310.21, score=54.0]} {Human: ENSG00000146085, MUT, methylmalonyl-CoA mutase, [RH, Score=982, Expect=0.0]} {Mouse: ENSMUSG00000023921, Mut, methylmalonyl-Coenzyme A mutase, [RH, Score=982, Expect=0.0]} {Celegans: WBGene00014202, mmcm-1, Probable methylmalonyl-CoA mutase, mitochondrial, [RH, Score=982, Expect=0.0]} {Smed: dd_Smed_v6_2255_0_1, dd_Smed_v6_2255_0_1, [RH, Score=997, Expect=0.0]} {RNA1509_779} {RNA1310_5402.1, RNA1509_779} {RNA1509_779, RNA815_1637}

Mlig455_059585 {REF} {Length: 3023} {TRANSSPLICED} {Pfam: Methylmalonyl-CoA mutase [PF01642.24, score=726.3]; B12 binding domain [PF02310.21, score=54.0]} {Human: ENSG00000146085, MUT, methylmalonyl-CoA mutase, [RH, Score=982, Expect=0.0]} {Mouse: ENSMUSG00000023921, Mut, methylmalonyl-Coenzyme A mutase, [RH, Score=982, Expect=0.0]} {Celegans: WBGene00014202, mmcm-1, Probable methylmalonyl-CoA mutase, mitochondrial, [RH, Score=982, Expect=0.0]} {Smed: dd_Smed_v6_2255_0_1, dd_Smed_v6_2255_0_1, [RH, Score=997, Expect=0.0]} {RNA1509_16567, RNA1509_779} {RNA1310_5402.1, RNA1509_16567} {RNA1509_16567, RNA815_1637}

Mlig455_069851 {REF} {Length: 3027} {TRANSSPLICED} {Pfam: Methylmalonyl-CoA mutase [PF01642.24, score=724.9]; B12 binding domain [PF02310.21, score=54.1]} {Human: ENSG00000146085, MUT, methylmalonyl-CoA mutase, [RH, Score=985, Expect=0.0]} {Mouse: ENSMUSG00000023921, Mut, methylmalonyl-Coenzyme A mutase, [RH, Score=985, Expect=0.0]} {Celegans: WBGene00014202, mmcm-1, Probable methylmalonyl-CoA mutase, mitochondrial, [RH, Score=984, Expect=0.0]} {Smed: dd_Smed_v6_2255_0_1, dd_Smed_v6_2255_0_1, [RH, Score=1000, Expect=0.0]} {RNA1509_3447, RNA1509_779} {RNA1310_5402.1, RNA1509_3447} {RNA1509_3447, RNA815_1637}
20. MligTC455_24058 874 18.21 Mlig455_049588

Neo: -

Age: logFC(26M/2M)=0.283

SYTL4 2.385 - - 0.705 - 0.971 0.709 Mlig455_049588 {REF} {Length: 12642} {TRANSSPLICED} {Pfam: C2 domain [PF00168.32, score=68.1]; FYVE-type zinc finger [PF02318.18, score=53.4]; Protein of unknown function (DUF3139) [PF11337.10, score=20.6]} {Human: ENSG00000102362, SYTL4, synaptotagmin like 4, [Score=100, Expect=3e-20]; ENSG00000147041, SYTL5, synaptotagmin like 5, [Score=99.0, Expect=1e-19]} {Mouse: ENSMUSG00000031255, Sytl4, synaptotagmin-like 4, [Score=100, Expect=3e-20]} {Dmel: FBgn0266756, btsz, bitesize, [Score=117, Expect=2e-25]} {Celegans: WBGene00004923, snt-3, SyNapTotagmin, [Score=57.8, Expect=5e-08]} {Smed: dd_Smed_v6_4335_0_1, dd_Smed_v6_4335_0_1, [Score=84.7, Expect=5e-16]} {RNA1509_12528, RNA1509_2527} {RNA1310_245.3, RNA1509_12528} {RNA1509_12528, RNA815_559.1}
21. MligTC455_51478 66 1.37 Mlig455_057080

Neo: -

Age: -

1.915 - - - 0.949 0.966 - Mlig455_057080 {REF} {Length: 1661} {Pfam: 7tm Chemosensory receptor [PF08395.14, score=33.2]; Trehalose receptor [PF06151.15, score=30.3]} {RNA1310_59684} {RNA815_43381}
22. MligTC455_41396 187 3.9 Mlig455_012937, Mlig455_031470

Neo: -

Age: -

Region-enriched R2: 4.167/0.01146

1.894 - - - 0.955 0.939 -

Mlig455_012937 {REF} {Length: 1911} {Smed: dd_Smed_v6_11196_0_1, dd_Smed_v6_11196_0_1, [Score=46.6, Expect=1e-06]} {RNA1509_16138} {RNA1310_24329} {RNA815_11818}

Mlig455_031470 {REF} {Length: 1745} {Dmel: FBgn0083971, CG34135, [RH, Score=60.1, Expect=1e-10]} {Smed: dd_Smed_v6_11196_0_1, dd_Smed_v6_11196_0_1, [RH, Score=96.3, Expect=3e-23]} {RNA1509_16138} {RNA1310_24329} {RNA815_11818}
23. MligTC455_13154 28 0.59 Mlig455_007824

Neo: -

Age: -

1.892 - - 0.915 - 0.977 - Mlig455_007824 {REF} {Length: 2457} {RNA1509_43477} {RNA1310_26398} {RNA815_11119}
24. MligTC455_19041 54 1.12 Mlig455_030662

Neo: -

Age: -

Region-enriched R2: 9.337/0.00002
Region-enriched R3: 6.044/0.00168

CAV1 1.886 - - - 0.952 0.934 - Mlig455_030662 {REF} {Length: 940} {Pfam: Caveolin [PF01146.19, score=117.8]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=98.2, Expect=1e-26]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=99.4, Expect=3e-27]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [Score=73.9, Expect=6e-17]} {Smed: dd_Smed_v6_6535_0_1, dd_Smed_v6_6535_0_1, [RH, Score=133, Expect=6e-41]} {RNA1509_53325} {RNA1310_97043} {RNA815_32565}
25. MligTC455_49663 245 5.1 Mlig455_013565

Neo: -

Age: -

CDH23 1.873 - - - 0.954 0.919 - Mlig455_013565 {REF} {Length: 7289} {Pfam: Cadherin domain [PF00028.19, score=361.2]; Cadherin-like [PF08266.14, score=38.9]} {Human: ENSG00000107736, CDH23, cadherin related 23, [Score=372, Expect=1e-103]} {Mouse: ENSMUSG00000012819, Cdh23, cadherin 23 (otocadherin), [Score=375, Expect=6e-105]} {Dmel: FBgn0038247, Cad88C, Cadherin 88C, [Score=362, Expect=2e-101]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=224, Expect=2e-58]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [Score=414, Expect=3e-118]} {RNA1509_16482} {RNA1310_682} {RNA815_249}
26. MligTC455_47234 19 0.39 Mlig455_051300

Neo: -

Age: Down-Up-Down

SCNN1B 1.865 - - - 0.895 0.970 - Mlig455_051300 {REF} {Length: 1753} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=169.2]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=57.4, Expect=5e-08]} {Mouse: ENSMUSG00000000216, Scnn1g, sodium channel, nonvoltage-gated 1 gamma, [Score=55.8, Expect=1e-07]} {Celegans: WBGene00003174, mec-10, Degenerin mec-10, [Score=57.8, Expect=2e-08]} {Smed: dd_Smed_v6_12037_0_1, dd_Smed_v6_12037_0_1, [Score=85.9, Expect=1e-17]} {RNA1310_54586}
27. MligTC455_50567 146 3.04 Mlig455_012858

Neo: -

Age: -

Region-specific R2: 6.162

Region-enriched R2: 5.988/0.01054

1.857 - - - 0.906 0.951 - Mlig455_012858 {REF} {Length: 1282} {Pfam: F5/8 type C domain [PF00754.27, score=27.5]} {Smed: dd_Smed_v6_36585_0_1, dd_Smed_v6_36585_0_1, [RH, Score=64.3, Expect=4e-12]} {RNA1310_34633} {RNA815_12537}
28. MligTC455_50566 40 0.84 Mlig455_061499

Neo: -

Age: -

Region-enriched R2: 5.243/0.02447

1.849 - - - 0.953 0.896 - Mlig455_061499 {REF} {Length: 484} {NoTransDecoderORF} {RNA1310_94077} {RNA815_47403}
29. MligTC455_25556 160 3.33 Mlig455_041382

Neo: -

Age: -

Region-specific R2: 5.503

Region-enriched R2: 4.706/0.00082

1.846 - - - 0.889 0.957 - Mlig455_041382 {REF} {Length: 1197} {RNA1509_55439} {RNA1310_65119, RNA1509_55439} {RNA1509_55439, RNA815_36098.2}
30. MligTC455_18619 527 10.97 Mlig455_030641, Mlig455_030999

Neo: -

Age: -

COL6A5 1.84 - - - 0.883 0.957 -

Mlig455_030641 {REF} {Length: 2413} {Pfam: Collagen triple helix repeat (20 copies) [PF01391.20, score=111.9]} {Human: ENSG00000172752, COL6A5, collagen type VI alpha 5 chain, [Score=129, Expect=6e-31]} {Mouse: ENSMUSG00000032572, Col6a4, collagen, type VI, alpha 4, [Score=96.7, Expect=2e-20]; ENSMUSG00000028197, Col24a1, collagen, type XXIV, alpha 1, [Score=95.5, Expect=5e-20]} {Dmel: FBgn0000299, Col4a1, Collagen type IV alpha 1, [Score=91.3, Expect=7e-19]} {Celegans: WBGene00000708, col-135, COLlagen, [Score=99.0, Expect=1e-21]} {Smed: dd_Smed_v6_9565_0_1, dd_Smed_v6_9565_0_1, [Score=111, Expect=2e-25]} {RNA1509_35455} {RNA1310_11079.1} {RNA815_14901}

Mlig455_030999 {REF} {Length: 2379} {Pfam: Collagen triple helix repeat (20 copies) [PF01391.20, score=97.0]} {Human: ENSG00000172752, COL6A5, collagen type VI alpha 5 chain, [Score=117, Expect=9e-27]} {Mouse: ENSMUSG00000031502, Col4a1, collagen, type IV, alpha 1, [Score=95.5, Expect=5e-20]; ENSMUSG00000026390, Marco, macrophage receptor with collagenous structure, [Score=91.7, Expect=3e-19]} {Dmel: FBgn0016075, vkg, viking, [Score=83.6, Expect=2e-16]} {Celegans: WBGene00000708, col-135, COLlagen, [Score=90.9, Expect=5e-19]} {Smed: dd_Smed_v6_9565_0_1, dd_Smed_v6_9565_0_1, [Score=105, Expect=1e-23]} {RNA1509_35455} {RNA1310_15043} {RNA815_14901}
31. MligTC455_47393 241 5.03 Mlig455_008718, Mlig455_063579

Neo: -

Age: Down-Up-Down

Region-enriched R2: 3.683/0.00849

CALM2 1.836 - - - 0.967 0.869 -

Mlig455_008718 {REF} {Length: 1727} {Pfam: EF hand [PF00036.34, score=99.3]; EF-hand domain pair [PF13499.8, score=95.1]; EF-hand domain [PF13405.8, score=86.1]; EF-hand domain pair [PF13833.8, score=76.8]; EF hand [PF13202.8, score=75.3]; EF-hand domain [PF14658.8, score=46.0]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=38.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=27.9]; EF-hand domain [PF08976.13, score=23.4]; Uncharacterised protein family (UPF0154) [PF03672.15, score=18.7]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=108, Expect=4e-30]; ENSG00000160014, CALM3, calmodulin 3, [Score=108, Expect=4e-30]; ENSG00000198668, CALM1, calmodulin 1, [Score=108, Expect=4e-30]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=108, Expect=2e-30]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=108, Expect=2e-30]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=108, Expect=2e-30]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=106, Expect=1e-29]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=107, Expect=3e-30]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=107, Expect=2e-30]} {Smed: dd_Smed_v6_3441_0_1, dd_Smed_v6_3441_0_1, [Score=114, Expect=8e-33]} {RNA1310_33847.1} {RNA815_17211}

Mlig455_063579 {REF} {Length: 2562} {Pfam: EF hand [PF00036.34, score=95.8]; EF-hand domain pair [PF13499.8, score=92.8]; EF-hand domain [PF13405.8, score=82.9]; EF-hand domain pair [PF13833.8, score=74.4]; EF hand [PF13202.8, score=72.2]; EF-hand domain [PF14658.8, score=43.8]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=38.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=25.6]; EF-hand domain [PF08976.13, score=21.4]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=111, Expect=7e-30]; ENSG00000198668, CALM1, calmodulin 1, [Score=108, Expect=3e-29]; ENSG00000160014, CALM3, calmodulin 3, [Score=108, Expect=3e-29]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=111, Expect=7e-30]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=108, Expect=2e-29]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=108, Expect=2e-29]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=106, Expect=9e-29]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=107, Expect=3e-29]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=107, Expect=2e-29]} {Smed: dd_Smed_v6_3441_0_1, dd_Smed_v6_3441_0_1, [Score=111, Expect=9e-31]} {RNA1310_12431.1} {RNA815_17211}
32. MligTC455_23150 3195 66.56 Mlig455_009524, Mlig455_009530

Neo: -

Age: -

Region-enriched R2: 3.504/0.00000
Region-enriched R3: 1.656/0.02560

CDK16 1.834 - - - 0.963 0.871 -

Mlig455_009524 {REF} {Length: 3287} {Pfam: Protein kinase domain [PF00069.27, score=218.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.2]} {Human: ENSG00000102225, CDK16, cyclin dependent kinase 16, [RH, Score=463, Expect=7e-159]; ENSG00000059758, CDK17, cyclin dependent kinase 17, [RH, Score=447, Expect=2e-151]} {Mouse: ENSMUSG00000031065, Cdk16, cyclin-dependent kinase 16, [RH, Score=464, Expect=2e-158]; ENSMUSG00000020015, Cdk17, cyclin-dependent kinase 17, [RH, Score=449, Expect=2e-152]} {Dmel: FBgn0005640, Eip63E, Ecdysone-induced protein 63E, [Score=362, Expect=2e-118]} {Celegans: WBGene00003961, pct-1, Cyclin-dependent kinase 17, [RH, Score=417, Expect=3e-138]} {Smed: dd_Smed_v6_4172_0_4, dd_Smed_v6_4172_0_4, [RH, Score=449, Expect=6e-151]} {RNA1509_23462} {RNA1310_21506} {RNA815_9702}

Mlig455_009530 {REF} {Length: 3384} {Pfam: Protein kinase domain [PF00069.27, score=208.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.4]; Haspin like kinase domain [PF12330.10, score=17.8]} {Human: ENSG00000102225, CDK16, cyclin dependent kinase 16, [Score=432, Expect=5e-147]} {Mouse: ENSMUSG00000031065, Cdk16, cyclin-dependent kinase 16, [Score=431, Expect=4e-146]} {Dmel: FBgn0005640, Eip63E, Ecdysone-induced protein 63E, [Score=329, Expect=9e-107]} {Celegans: WBGene00003961, pct-1, Cyclin-dependent kinase 17, [Score=392, Expect=2e-130]} {Smed: dd_Smed_v6_4172_0_4, dd_Smed_v6_4172_0_4, [Score=411, Expect=6e-137]} {RNA1509_23462} {RNA1310_21506} {RNA815_9702}
33. MligTC455_24523 144 2.99 Mlig455_010636, Mlig455_010724

Neo: -

Age: -

Region-enriched R2: 9.355/0.00000

RGS6 1.829 - - - 0.877 0.952 -

Mlig455_010636 {REF} {Length: 2512} {Pfam: Regulator of G-protein signalling DHEX domain [PF18148.3, score=118.4]; Regulator of G protein signaling domain [PF00615.21, score=116.4]; Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) [PF00610.23, score=31.3]} {Human: ENSG00000182732, RGS6, regulator of G protein signaling 6, [Score=301, Expect=3e-95]} {Mouse: ENSMUSG00000021219, Rgs6, regulator of G-protein signaling 6, [Score=299, Expect=2e-94]; ENSMUSG00000026527, Rgs7, regulator of G protein signaling 7, [Score=290, Expect=6e-91]} {Dmel: FBgn0259927, CG42450, [RH, Score=327, Expect=2e-98]} {Celegans: WBGene00001145, eat-16, [Score=217, Expect=1e-63]} {Smed: dd_Smed_v6_5311_0_1, dd_Smed_v6_5311_0_1, [RH, Score=384, Expect=1e-127]} {RNA1509_59108} {RNA1310_13711, RNA1509_59108} {RNA1509_59108, RNA815_9935}

Mlig455_010724 {REF} {Length: 2512} {Pfam: Regulator of G-protein signalling DHEX domain [PF18148.3, score=118.4]; Regulator of G protein signaling domain [PF00615.21, score=113.1]; Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) [PF00610.23, score=31.3]} {Human: ENSG00000182732, RGS6, regulator of G protein signaling 6, [Score=299, Expect=2e-94]} {Mouse: ENSMUSG00000021219, Rgs6, regulator of G-protein signaling 6, [Score=297, Expect=2e-93]; ENSMUSG00000026527, Rgs7, regulator of G protein signaling 7, [Score=287, Expect=4e-90]} {Dmel: FBgn0259927, CG42450, [RH, Score=324, Expect=1e-97]} {Celegans: WBGene00001145, eat-16, [Score=214, Expect=8e-63]} {Smed: dd_Smed_v6_5311_0_1, dd_Smed_v6_5311_0_1, [RH, Score=382, Expect=8e-127]} {RNA1509_59108} {RNA1310_13711} {RNA815_9935}
34. MligTC455_29914 44 0.91 Mlig455_027923

Neo: -

Age: Down-Up-Down

Region-enriched R2: 8.096/0.00455

ANGPTL3 1.816 - - - 0.856 0.960 - Mlig455_027923 {REF} {Length: 1663} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=70.5]} {Human: ENSG00000132855, ANGPTL3, angiopoietin like 3, [Score=60.5, Expect=9e-10]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=59.3, Expect=2e-09]; ENSG00000120332, TNN, tenascin N, [Score=58.9, Expect=3e-09]} {Mouse: ENSMUSG00000015829, Tnr, tenascin R, [Score=62.4, Expect=2e-10]} {Dmel: FBgn0031804, CG9500, [Score=76.3, Expect=6e-16]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=51.2, Expect=3e-07]} {RNA1509_53291} {RNA1310_58974} {RNA815_43288.3}
35. MligTC455_50601 21 0.44 Mlig455_018462

Neo: -

Age: -

1.811 - - - 0.860 0.951 - Mlig455_018462 {REF} {Length: 2878} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=164.0]} {Smed: dd_Smed_v6_37545_0_1, dd_Smed_v6_37545_0_1, [Score=117, Expect=1e-27]} {RNA1310_8235} {RNA815_10456.1}
36. MligTC455_56421 59 1.23 Mlig455_066824

Neo: -

Age: -

1.81 - - - 0.960 0.850 - Mlig455_066824 {REF} {Length: 413} {RNA1509_38728} {RNA1310_9789} {RNA815_21216}
37. MligTC455_19429 537 11.18 Mlig455_016019

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.664

Region-enriched R2: 1.983/0.00165

WDR49 1.808 - - 0.849 - 0.959 - Mlig455_016019 {REF} {Length: 4260} {Pfam: WD domain, G-beta repeat [PF00400.34, score=59.6]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=29.3]; EF-hand domain pair [PF13833.8, score=22.2]; EF-hand domain pair [PF13499.8, score=20.7]} {Human: ENSG00000174776, WDR49, WD repeat domain 49, [Score=310, Expect=1e-88]} {Mouse: ENSMUSG00000104301, Wdr49, WD repeat domain 49, [Score=232, Expect=7e-64]; ENSMUSG00000029658, Wdr95, WD40 repeat domain 95, [Score=231, Expect=4e-63]; ENSMUSG00000044083, Efcab8, EF-hand calcium binding domain 8, [Score=226, Expect=9e-60]} {Dmel: FBgn0267449, WDY, WD40 Y, [Score=180, Expect=9e-46]} {Smed: dd_Smed_v6_5437_0_2, dd_Smed_v6_5437_0_2, [Score=306, Expect=3e-87]} {RNA1509_3708} {RNA1310_2384.2, RNA1509_3708} {RNA1509_3708, RNA815_724.1}
38. MligTC455_24398 63 1.31 Mlig455_040650

Neo: -

Age: -

1.807 - - 0.952 - - 0.855 Mlig455_040650 {REF} {Length: 2026} {RNA1509_54646} {RNA1310_12048} {RNA815_7357}
39. MligTC455_19660 1113 23.18 Mlig455_042835, Mlig455_045853, Mlig455_045869

Neo: -

Age: -

Region-enriched R2: 7.811/0.00000
Region-enriched R3: 5.032/0.00323
Region-enriched R5: 3.512/0.04347

CEP164 1.802 - - 0.847 - 0.955 -

Mlig455_042835 {REF} {Length: 1693} {Pfam: WW domain [PF00397.28, score=23.4]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=69.3, Expect=5e-12]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=71.2, Expect=7e-13]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=73.6, Expect=5e-14]} {RNA1310_28636} {RNA815_10722}

Mlig455_045853 {REF} {Length: 1697} {Pfam: WW domain [PF00397.28, score=23.4]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=68.9, Expect=5e-12]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=71.2, Expect=7e-13]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=73.6, Expect=6e-14]} {RNA1310_28636} {RNA815_10722}

Mlig455_045869 {REF} {Length: 1704} {Pfam: WW domain [PF00397.28, score=23.4]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=68.9, Expect=5e-12]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=71.2, Expect=7e-13]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=73.6, Expect=6e-14]} {RNA1310_28636} {RNA815_10722}
40. MligTC455_17806 20 0.42 Mlig455_044877

Neo: -

Age: -

1.801 - - - 0.849 0.952 - Mlig455_044877 {REF} {Length: 1723} {Pfam: F5/8 type C domain [PF00754.27, score=29.9]} {Smed: dd_Smed_v6_83746_0_1, dd_Smed_v6_83746_0_1, [RH, Score=67.8, Expect=2e-14]} {RNA1310_72359} {RNA815_40265}
41. MligTC455_39391 80 1.66 Mlig455_058620

Neo: -

Age: Down-Up-Up

NKX1-1 1.799 - - - - 0.960 0.839 Mlig455_058620 {REF} {Length: 1956} {Pfam: Homeodomain [PF00046.31, score=76.6]} {Human: ENSG00000235608, NKX1-1, NK1 homeobox 1, [RH, Score=137, Expect=2e-36]; ENSG00000229544, NKX1-2, NK1 homeobox 2, [RH, Score=132, Expect=2e-35]} {Mouse: ENSMUSG00000029112, Nkx1-1, NK1 homeobox 1, [RH, Score=140, Expect=8e-38]; ENSMUSG00000048528, Nkx1-2, NK1 homeobox 2, [RH, Score=133, Expect=7e-36]} {Dmel: FBgn0002941, slou, slouch, [RH, Score=139, Expect=4e-36]} {Celegans: WBGene00000428, ceh-1, Homeobox protein ceh-1, [RH, Score=130, Expect=1e-36]} {Smed: dd_Smed_v6_19327_0_1, dd_Smed_v6_19327_0_1, [RH, Score=135, Expect=1e-36]} {RNA1310_82194} {RNA815_51897}
42. MligTC455_18787 963 20.06 Mlig455_014022

Neo: -

Age: -

Region-enriched R2: 1.334/0.03482

STRC 1.78 - - - 0.829 0.951 - Mlig455_014022 {REF} {Length: 5754} {Human: ENSG00000242866, STRC, stereocilin, [RH, Score=76.3, Expect=4e-13]} {Mouse: ENSMUSG00000033498, Strc, stereocilin, [RH, Score=80.9, Expect=1e-14]} {RNA1509_4378} {RNA1310_1493.1, RNA1509_4378} {RNA1509_4378, RNA815_804}
43. MligTC455_47458 542 11.29 Mlig455_039325

Neo: -

Age: logFC(26M/2M)=-0.279

LRRC71 1.78 - - 0.818 - 0.962 - Mlig455_039325 {REF} {Length: 2138} {TRANSSPLICED} {Pfam: Leucine Rich repeat [PF13516.8, score=71.0]; Leucine Rich repeats (2 copies) [PF12799.9, score=26.7]} {Human: ENSG00000160838, LRRC71, leucine rich repeat containing 71, [Score=184, Expect=4e-51]} {Mouse: ENSMUSG00000023084, Lrrc71, leucine rich repeat containing 71, [Score=181, Expect=3e-50]} {Smed: dd_Smed_v6_12043_0_2, dd_Smed_v6_12043_0_2, [RH, Score=225, Expect=3e-68]} {RNA1509_17632} {RNA1310_9823, RNA1509_17632} {RNA1509_17632, RNA815_14689.1}
44. MligTC455_21635 1157 24.11 Mlig455_026396

Neo: -

Age: -

SLC6A5 1.777 - - - 0.820 0.957 - Mlig455_026396 {REF} {Length: 3636} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=612.2]} {Human: ENSG00000165970, SLC6A5, solute carrier family 6 member 5, [Score=486, Expect=2e-161]} {Mouse: ENSMUSG00000039728, Slc6a5, solute carrier family 6 (neurotransmitter transporter, glycine), member 5, [Score=490, Expect=6e-163]} {Dmel: FBgn0034911, CG5549, [Score=499, Expect=2e-162]} {Celegans: WBGene00004905, snf-6, Sodium-dependent acetylcholine transporter, [RH, Score=374, Expect=2e-119]} {Smed: dd_Smed_v6_10458_0_1, dd_Smed_v6_10458_0_1, [Score=459, Expect=1e-152]} {RNA1509_26562} {RNA1310_4707.2, RNA1509_26562} {RNA1509_26562, RNA815_1349.2}
45. MligTC455_33802 659 13.73 Mlig455_033383

Neo: -

Age: logFC(26M/2M)=-0.359

1.774 - - - - 0.971 0.803 Mlig455_033383 {REF} {Length: 3524} {RNA1509_14410, RNA1509_56133} {RNA1310_8398, RNA1509_56133} {RNA1509_56133, RNA815_14639}
46. MligTC455_34614 24 0.5 Mlig455_060978

Neo: -

Age: -

1.765 - - - 0.810 0.955 - Mlig455_060978 {REF} {Length: 1770} {RNA1310_81929}
47. MligTC455_43293 2619 54.57 Mlig455_001393

Neo: -

Age: -

Region-specific R2: 1.579

ANXA7 1.764 - - 0.807 - 0.957 - Mlig455_001393 {REF} {Length: 4698} {Pfam: Annexin [PF00191.22, score=268.6]} {Human: ENSG00000138279, ANXA7, annexin A7, [RH, Score=307, Expect=6e-98]} {Mouse: ENSMUSG00000021814, Anxa7, annexin A7, [RH, Score=301, Expect=8e-96]} {Dmel: FBgn0000083, AnxB9, Annexin B9, [Score=259, Expect=4e-82]} {Celegans: WBGene00003589, nex-2, Annexin, [Score=261, Expect=2e-81]} {Smed: dd_Smed_v6_1735_0_1, dd_Smed_v6_1735_0_1, [Score=270, Expect=6e-86]} {RNA1509_5239} {RNA1310_11340, RNA1509_5239} {RNA1509_5239, RNA815_3977}
48. MligTC455_53487 49 1.01 Mlig455_006106

Neo: -

Age: Down-Down-Up

FBXL7 1.76 - - 0.808 - 0.952 - Mlig455_006106 {REF} {Length: 3312} {Pfam: F-box-like [PF12937.9, score=46.0]; Leucine Rich repeat [PF13516.8, score=39.7]; F-box domain [PF00646.35, score=28.7]} {Human: ENSG00000183580, FBXL7, F-box and leucine rich repeat protein 7, [Score=151, Expect=3e-39]} {Mouse: ENSMUSG00000043556, Fbxl7, F-box and leucine-rich repeat protein 7, [Score=152, Expect=2e-39]} {Dmel: FBgn0038385, Fbxl7, F-box and leucine-rich repeat protein 7, [Score=154, Expect=2e-39]} {Celegans: WBGene00015350, fbxl-1, Uncharacterized F-box/LRR-repeat protein C02F5.7, [Score=99.8, Expect=4e-22]} {Smed: dd_Smed_v6_10647_0_1, dd_Smed_v6_10647_0_1, [Score=102, Expect=8e-23]} {RNA1310_5789.1} {RNA815_11910}
49. MligTC455_53488 50 1.05 Mlig455_055274

Neo: -

Age: -

FBXL7 1.76 - - 0.808 - 0.952 - Mlig455_055274 {REF} {Length: 3372} {Pfam: Leucine Rich repeat [PF13516.8, score=59.3]; F-box-like [PF12937.9, score=46.1]; Leucine Rich repeats (2 copies) [PF12799.9, score=35.0]; F-box domain [PF00646.35, score=27.2]} {Human: ENSG00000183580, FBXL7, F-box and leucine rich repeat protein 7, [RH, Score=174, Expect=5e-49]} {Mouse: ENSMUSG00000043556, Fbxl7, F-box and leucine-rich repeat protein 7, [RH, Score=176, Expect=2e-49]} {Dmel: FBgn0038385, Fbxl7, F-box and leucine-rich repeat protein 7, [Score=171, Expect=2e-46]} {Celegans: WBGene00015350, fbxl-1, Uncharacterized F-box/LRR-repeat protein C02F5.7, [Score=112, Expect=4e-27]} {Smed: dd_Smed_v6_10647_0_1, dd_Smed_v6_10647_0_1, [RH, Score=111, Expect=3e-26]} {RNA1310_5789.1} {RNA815_11910}
50. MligTC455_41324 401 8.35 Mlig455_024997

Neo: -

Age: Up-Down-Down

CCDC151 1.758 - - - 0.773 0.985 - Mlig455_024997 {REF} {Length: 2376} {TRANSSPLICED} {Human: ENSG00000198003, CCDC151, coiled-coil domain containing 151, [Score=251, Expect=5e-75]} {Mouse: ENSMUSG00000039632, Ccdc151, coiled-coil domain containing 151, [Score=261, Expect=4e-79]} {Dmel: FBgn0036219, CCDC151, Coiled-coil domain containing protein 151, [Score=111, Expect=2e-25]} {Smed: dd_Smed_v6_4526_0_1, dd_Smed_v6_4526_0_1, [Score=463, Expect=3e-158]} {RNA1509_18758} {RNA1310_9513.1, RNA1509_18758} {RNA1509_18758, RNA815_13766}
51. MligTC455_50375 2086 43.45 Mlig455_016459, Mlig455_016525, Mlig455_049814

Neo: -

Age: -

1.758 - - - 0.798 0.960 -

Mlig455_016459 {REF} {Length: 2149} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=23.2]; Ankyrin repeats (many copies) [PF13637.8, score=20.7]} {Smed: dd_Smed_v6_17861_0_1, dd_Smed_v6_17861_0_1, [RH, Score=120, Expect=2e-30]} {RNA1509_10140} {RNA1310_11634.1} {RNA815_4167}

Mlig455_016525 {REF} {Length: 2207} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=23.2]; Ankyrin repeats (many copies) [PF13637.8, score=20.7]} {Smed: dd_Smed_v6_17861_0_1, dd_Smed_v6_17861_0_1, [RH, Score=120, Expect=2e-30]} {RNA1509_10140, RNA1509_60156} {RNA1310_11634.1, RNA1509_10140, RNA1509_60156} {RNA1509_10140, RNA1509_60156, RNA815_4167}

Mlig455_049814 {REF} {Length: 2210} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=23.2]; Ankyrin repeats (many copies) [PF13637.8, score=20.7]} {Smed: dd_Smed_v6_17861_0_1, dd_Smed_v6_17861_0_1, [RH, Score=120, Expect=2e-30]} {RNA1509_10140} {RNA1310_11634.1} {RNA815_4167}
52. MligTC455_07030 347 7.23 Mlig455_026901, Mlig455_030792, Mlig455_048033

Neo: -

Age: Up-Down-Down

Region-enriched R8: 3.182/0.03347
Region-enriched R2: 3.034/0.01060

KIF1A 1.756 - - - 0.961 0.795 -

Mlig455_026901 {REF} {Length: 5213} {Pfam: Kinesin-associated [PF16183.7, score=194.5]; Kinesin protein [PF12473.10, score=106.0]; PH domain [PF00169.31, score=42.3]; Kinesin protein 1B [PF12423.10, score=37.6]; FHA domain [PF00498.28, score=32.9]; Kinesin motor domain [PF00225.25, score=25.4]; Inner membrane component of T3SS, cytoplasmic domain [PF16697.7, score=25.3]} {Human: ENSG00000130294, KIF1A, kinesin family member 1A, [Score=966, Expect=0.0]} {Mouse: ENSMUSG00000014602, Kif1a, kinesin family member 1A, [Score=962, Expect=0.0]} {Dmel: FBgn0267002, unc-104, uncoordinated-104, [Score=967, Expect=0.0]} {Celegans: WBGene00006831, unc-104, Kinesin-like protein unc-104, [Score=865, Expect=0.0]} {Smed: dd_Smed_v6_7108_0_1, dd_Smed_v6_7108_0_1, [Score=1137, Expect=0.0]} {RNA1509_24107} {RNA1310_2812.1} {RNA815_13100}

Mlig455_030792 {REF} {Length: 6718} {Pfam: Kinesin motor domain [PF00225.25, score=369.4]; Kinesin-associated [PF16183.7, score=194.3]; Kinesin protein [PF12473.10, score=105.2]; Microtubule binding [PF16796.7, score=64.0]; PH domain [PF00169.31, score=42.1]; Kinesin protein 1B [PF12423.10, score=37.6]; FHA domain [PF00498.28, score=33.7]; Inner membrane component of T3SS, cytoplasmic domain [PF16697.7, score=25.0]} {Human: ENSG00000130294, KIF1A, kinesin family member 1A, [Score=1434, Expect=0.0]} {Mouse: ENSMUSG00000014602, Kif1a, kinesin family member 1A, [Score=1431, Expect=0.0]} {Dmel: FBgn0267002, unc-104, uncoordinated-104, [Score=1431, Expect=0.0]} {Celegans: WBGene00006831, unc-104, Kinesin-like protein unc-104, [RH, Score=1296, Expect=0.0]} {Smed: dd_Smed_v6_7108_0_2, dd_Smed_v6_7108_0_2, [Score=1566, Expect=0.0]} {RNA1509_24107} {RNA1310_2896} {RNA815_13100}

Mlig455_048033 {REF} {Length: 116} {NoTransDecoderORF} {RNA1310_101965} {RNA815_46048}
53. MligTC455_18599 119 2.47 Mlig455_031197

Neo: -

Age: Down-Up-Up

Region-enriched R2: 4.553/0.00808

1.756 - - - 0.957 0.799 - Mlig455_031197 {REF} {Length: 1284} {RNA1310_35452}
54. MligTC455_42037 1931 40.23 Mlig455_063391

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.444

Region-specific R2: 2.479

Region-enriched R2: 1.442/0.00136

1.755 - - - 0.791 0.964 - Mlig455_063391 {REF} {Length: 1482} {RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236} {RNA1310_24553, RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236} {RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236, RNA815_11766}
55. MligTC455_54217 941 19.61 Mlig455_013990

Neo: -

Age: logFC(26M/2M)=-0.425

1.753 - - 0.800 - 0.953 - Mlig455_013990 {REF} {Length: 3670} {RNA1509_11789} {RNA1310_16926.2, RNA1509_11789} {RNA1509_11789, RNA815_9044}
56. MligTC455_38657 292 6.08 Mlig455_021581

Neo: -

Age: -

CPLX1 1.752 - - - 0.785 0.967 - Mlig455_021581 {REF} {Length: 2085} {Pfam: Synaphin protein [PF05835.14, score=132.9]} {Human: ENSG00000168993, CPLX1, complexin 1, [Score=52.4, Expect=8e-09]; ENSG00000145920, CPLX2, complexin 2, [Score=50.8, Expect=1e-08]} {Mouse: ENSMUSG00000033615, Cplx1, complexin 1, [Score=53.5, Expect=2e-09]} {Dmel: FBgn0041605, cpx, complexin, [RH, Score=90.1, Expect=1e-23]} {Celegans: WBGene00022271, cpx-1, Putative complexin-1, [RH, Score=99.4, Expect=2e-27]} {Smed: dd_Smed_v6_9918_0_1, dd_Smed_v6_9918_0_1, [Score=94.4, Expect=2e-25]} {RNA1509_37151, RNA1509_38047} {RNA1310_51275, RNA1509_38047} {RNA1509_38047, RNA815_22799}
57. MligTC455_21637 2229 46.44 Mlig455_052609, Mlig455_052656

Neo: -

Age: -

Region-enriched R2: 1.063/0.02338

SLC6A5 1.749 - - - 0.782 0.967 -

Mlig455_052609 {REF} {Length: 3232} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=607.1]} {Human: ENSG00000165970, SLC6A5, solute carrier family 6 member 5, [Score=493, Expect=9e-164]} {Mouse: ENSMUSG00000039728, Slc6a5, solute carrier family 6 (neurotransmitter transporter, glycine), member 5, [Score=496, Expect=2e-165]} {Dmel: FBgn0034911, CG5549, [Score=500, Expect=1e-162]} {Celegans: WBGene00004905, snf-6, Sodium-dependent acetylcholine transporter, [RH, Score=383, Expect=6e-123]} {Smed: dd_Smed_v6_10458_0_1, dd_Smed_v6_10458_0_1, [Score=458, Expect=3e-152]} {RNA1509_11553} {RNA1310_4707.1} {RNA815_1349.1}

Mlig455_052656 {REF} {Length: 3033} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=472.2]} {Human: ENSG00000165970, SLC6A5, solute carrier family 6 member 5, [Score=387, Expect=2e-124]} {Mouse: ENSMUSG00000039728, Slc6a5, solute carrier family 6 (neurotransmitter transporter, glycine), member 5, [Score=388, Expect=6e-125]} {Dmel: FBgn0034911, CG5549, [Score=390, Expect=3e-122]} {Celegans: WBGene00004905, snf-6, Sodium-dependent acetylcholine transporter, [Score=291, Expect=6e-89]} {Smed: dd_Smed_v6_10458_0_1, dd_Smed_v6_10458_0_1, [Score=353, Expect=5e-113]} {RNA1509_26562} {RNA1310_4707.1} {RNA815_1349.1}
58. MligTC455_07563 21 0.43 Mlig455_045090

Neo: -

Age: -

1.743 - - - - 0.970 0.773 Mlig455_045090 {REF} {Length: 953} {NoTransDecoderORF}
59. MligTC455_14176 30 0.63 Mlig455_058283

Neo: -

Age: -

1.743 - - 0.788 0.955 - - Mlig455_058283 {REF} {Length: 1230} {NoTransDecoderORF} {RNA1509_16231} {RNA1310_87164} {RNA815_8904.1}
60. MligTC455_45837 631 13.15 Mlig455_055002

Neo: -

Age: -

1.743 - - 0.780 - 0.963 - Mlig455_055002 {REF} {Length: 821} {RNA1509_3859} {RNA1310_9281} {RNA815_3282}
61. MligTC455_40654 676 14.08 Mlig455_056785

Neo: -

Age: logFC(26M/2M)=-0.402

CCDC63 1.742 - - - 0.771 0.971 - Mlig455_056785 {REF} {Length: 2093} {TRANSSPLICED} {Pfam: Initiation control protein YabA [PF06156.15, score=20.5]} {Human: ENSG00000173093, CCDC63, coiled-coil domain containing 63, [RH, Score=190, Expect=9e-53]} {Mouse: ENSMUSG00000043036, Ccdc63, coiled-coil domain containing 63, [RH, Score=179, Expect=7e-49]} {Dmel: FBgn0038452, CG14905, [RH, Score=168, Expect=6e-46]} {Smed: dd_Smed_v6_4191_0_1, dd_Smed_v6_4191_0_1, [RH, Score=442, Expect=7e-150]} {RNA1509_17628} {RNA1310_12386, RNA1509_17628} {RNA1509_17628, RNA815_7054}
62. MligTC455_39467 6156 128.24 Mlig455_066728, Mlig455_066742

Neo: -

Age: logFC(26M/2M)=-0.137

Region-specific R2: 2.002

Region-enriched R2: 1.402/0.00004

PC 1.735 - - 0.772 - 0.963 -

Mlig455_066728 {REF} {Length: 4310} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=220.4]; Conserved carboxylase domain [PF02436.20, score=216.0]; Biotin carboxylase, N-terminal domain [PF00289.24, score=144.7]; Biotin carboxylase C-terminal domain [PF02785.21, score=102.8]; HMGL-like [PF00682.21, score=93.0]; Biotin-requiring enzyme [PF00364.24, score=57.9]; Biotin-lipoyl like [PF13533.8, score=28.3]; D-ala D-ala ligase C-terminus [PF07478.15, score=25.5]; ATP-grasp domain [PF02222.24, score=24.6]} {Human: ENSG00000173599, PC, pyruvate carboxylase, [Score=1375, Expect=0.0]} {Mouse: ENSMUSG00000024892, Pcx, pyruvate carboxylase, [Score=1365, Expect=0.0]} {Dmel: FBgn0027580, PCB, Pyruvate carboxylase, [Score=1419, Expect=0.0]} {Celegans: WBGene00004258, pyc-1, Pyruvate carboxylase 1, [Score=1371, Expect=0.0]} {Smed: dd_Smed_v6_2393_0_1, dd_Smed_v6_2393_0_1, [Score=1440, Expect=0.0]} {RNA1509_292} {RNA1310_1178} {RNA815_516.1}

Mlig455_066742 {REF} {Length: 4334} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=265.4]; Biotin carboxylase, N-terminal domain [PF00289.24, score=117.2]; Biotin carboxylase C-terminal domain [PF02785.21, score=104.0]; ATP-grasp domain [PF02222.24, score=37.0]; D-ala D-ala ligase C-terminus [PF07478.15, score=34.3]; ATP-grasp domain [PF02655.16, score=18.8]; HMGL-like [PF00682.21, score=18.3]} {Human: ENSG00000173599, PC, pyruvate carboxylase, [Score=837, Expect=0.0]} {Mouse: ENSMUSG00000024892, Pcx, pyruvate carboxylase, [Score=826, Expect=0.0]} {Dmel: FBgn0027580, PCB, Pyruvate carboxylase, [Score=839, Expect=0.0]} {Celegans: WBGene00004258, pyc-1, Pyruvate carboxylase 1, [Score=808, Expect=0.0]} {Smed: dd_Smed_v6_2393_0_1, dd_Smed_v6_2393_0_1, [Score=851, Expect=0.0]} {RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579} {RNA1310_1642, RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579} {RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579, RNA815_516.1}
63. MligTC455_24270 71 1.47 Mlig455_005120

Neo: -

Age: -

CHRNA7 1.734 - - - 0.761 0.973 - Mlig455_005120 {REF} {Length: 1530} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=115.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=66.6]} {Human: ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=148, Expect=4e-39]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=147, Expect=5e-39]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=145, Expect=4e-38]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=146, Expect=2e-38]; ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=140, Expect=1e-36]} {Dmel: FBgn0028875, nAChRalpha5, nicotinic Acetylcholine Receptor alpha5, [Score=135, Expect=5e-34]} {Celegans: WBGene00000060, acr-21, AcetylCholine Receptor, [Score=134, Expect=9e-35]} {Smed: dd_Smed_v6_8058_0_1, dd_Smed_v6_8058_0_1, [Score=133, Expect=4e-34]} {RNA1509_43533} {RNA1310_20839.2} {RNA815_22406}
64. MligTC455_54230 22 0.46 Mlig455_033979

Neo: Int S/G2/M

Age: -

1.731 - - - - 0.955 0.776 Mlig455_033979 {REF} {Length: 3178} {RNA1310_82897} {RNA815_45268}
65. MligTC455_39518 40 0.83 Mlig455_031401

Neo: -

Age: -

CHRNA1 1.727 - - - 0.776 0.951 - Mlig455_031401 {REF} {Length: 2411} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=92.9]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=76.4]} {Human: ENSG00000138435, CHRNA1, cholinergic receptor nicotinic alpha 1 subunit, [Score=120, Expect=3e-29]; ENSG00000166736, HTR3A, 5-hydroxytryptamine receptor 3A, [Score=120, Expect=2e-29]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=115, Expect=2e-27]; ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=114, Expect=3e-27]} {Mouse: ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=134, Expect=2e-34]} {Dmel: FBgn0004118, nAChRbeta2, nicotinic Acetylcholine Receptor beta2, [Score=135, Expect=1e-34]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=124, Expect=5e-31]} {Smed: dd_Smed_v6_23922_0_1, dd_Smed_v6_23922_0_1, [Score=114, Expect=2e-27]} {RNA1509_53098} {RNA1310_67430} {RNA815_23438}
66. MligTC455_43786 401 8.35 Mlig455_054385

Neo: -

Age: -

CCDC60 1.714 - - - - 0.962 0.752 Mlig455_054385 {REF} {Length: 3003} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4698) [PF15769.7, score=170.6]} {Human: ENSG00000183273, CCDC60, coiled-coil domain containing 60, [Score=62.8, Expect=2e-09]} {Mouse: ENSMUSG00000043913, Ccdc60, coiled-coil domain containing 60, [Score=62.4, Expect=1e-09]} {Smed: dd_Smed_v6_14286_0_1, dd_Smed_v6_14286_0_1, [Score=115, Expect=1e-26]} {RNA1509_58886} {RNA1310_1558.2} {RNA815_11153}
67. MligTC455_49143 772 16.08 Mlig455_021704

Neo: -

Age: -

Region-enriched R2: 1.427/0.03420

1.712 - - - - 0.971 0.741 Mlig455_021704 {REF} {Length: 2489} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4537) [PF15057.8, score=48.8]} {Smed: dd_Smed_v6_13233_0_2, dd_Smed_v6_13233_0_2, [Score=60.1, Expect=4e-09]} {RNA1509_11962} {RNA1310_8951.1, RNA1509_11962}
68. MligTC455_15598 45 0.94 Mlig455_021461

Neo: -

Age: Down-Up-Up

1.704 - - - 0.733 0.971 - Mlig455_021461 {REF} {Length: 2020} {RNA1310_35982.1} {RNA815_27626}
69. MligTC455_16248 132 2.74 Mlig455_038325, Mlig455_050222, Mlig455_050231

Neo: -

Age: -

CHRNA3 1.704 - - - 0.751 0.953 -

Mlig455_038325 {REF} {Length: 1078} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=200.0]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=192, Expect=4e-57]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=194, Expect=7e-58]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=190, Expect=1e-56]} {Dmel: FBgn0004118, nAChRbeta2, nicotinic Acetylcholine Receptor beta2, [Score=206, Expect=1e-62]} {Celegans: WBGene00006774, unc-38, Acetylcholine receptor subunit alpha-type unc-38, [Score=186, Expect=4e-55]} {Smed: dd_Smed_v6_9799_0_1, dd_Smed_v6_9799_0_1, [Score=216, Expect=5e-67]} {RNA1310_44575} {RNA815_22042}

Mlig455_050222 {REF} {Length: 2164} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=202.4]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=197.9]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=348, Expect=5e-114]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=335, Expect=4e-109]} {Mouse: ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=348, Expect=2e-114]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=343, Expect=2e-112]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=335, Expect=5e-109]} {Dmel: FBgn0266347, nAChRalpha4, nicotinic Acetylcholine Receptor alpha4, [Score=397, Expect=1e-133]} {Celegans: WBGene00006774, unc-38, Acetylcholine receptor subunit alpha-type unc-38, [Score=338, Expect=2e-110]} {Smed: dd_Smed_v6_9799_0_1, dd_Smed_v6_9799_0_1, [Score=489, Expect=5e-170]} {RNA1310_44575} {RNA815_22042}

Mlig455_050231 {REF} {Length: 2219} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=203.3]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=143.9]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=304, Expect=5e-99]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=299, Expect=8e-97]; ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=293, Expect=2e-94]; ENSG00000101204, CHRNA4, cholinergic receptor nicotinic alpha 4 subunit, [Score=290, Expect=7e-92]} {Mouse: ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=302, Expect=3e-98]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=296, Expect=3e-96]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=291, Expect=5e-94]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [Score=352, Expect=8e-117]} {Celegans: WBGene00006797, unc-63, Acetylcholine receptor subunit alpha-type unc-63, [Score=303, Expect=5e-99]} {Smed: dd_Smed_v6_9799_0_1, dd_Smed_v6_9799_0_1, [Score=424, Expect=2e-146]} {RNA1310_44575} {RNA815_22042}
70. MligTC455_29049 441 9.18 Mlig455_042244

Neo: -

Age: -

Region-enriched R2: 4.677/0.00000
Region-enriched R3: 2.595/0.01002

RASGRF1 1.701 - - - - 0.953 0.748 Mlig455_042244 {REF} {Length: 6465} {Pfam: RasGEF domain [PF00617.21, score=193.2]; RhoGEF domain [PF00621.22, score=119.3]; PH domain [PF00169.31, score=86.7]; RasGEF N-terminal motif [PF00618.22, score=68.4]; Pleckstrin homology domain [PF15413.8, score=22.6]} {Human: ENSG00000058335, RASGRF1, Ras protein specific guanine nucleotide releasing factor 1, [RH, Score=763, Expect=0.0]; ENSG00000113319, RASGRF2, Ras protein specific guanine nucleotide releasing factor 2, [RH, Score=739, Expect=0.0]} {Mouse: ENSMUSG00000032356, Rasgrf1, RAS protein-specific guanine nucleotide-releasing factor 1, [RH, Score=763, Expect=0.0]} {Dmel: FBgn0001965, Sos, Son of sevenless, [Score=164, Expect=3e-40]} {Celegans: WBGene00004947, sos-1, Son of sevenless homolog, [Score=118, Expect=3e-26]} {Smed: dd_Smed_v6_18313_0_2, dd_Smed_v6_18313_0_2, [RH, Score=1137, Expect=0.0]} {RNA1509_15697} {RNA1310_2543.1} {RNA815_8228.1}
71. MligTC455_19908 490 10.21 Mlig455_047266, Mlig455_047318, Mlig455_069346

Neo: -

Age: logFC(26M/2M)=0.566

1.698 - - - 0.720 0.978 -

Mlig455_047266 {REF} {Length: 1728} {Pfam: Glycine rich protein [PF12810.9, score=49.4]} {RNA1509_28009} {RNA1310_17226} {RNA815_32720}

Mlig455_047318 {REF} {Length: 2268} {Pfam: Glycine rich protein [PF12810.9, score=36.7]} {RNA1509_28009} {RNA1310_17226, RNA1509_28009} {RNA1509_28009, RNA815_32720}

Mlig455_069346 {REF} {Length: 1953} {Pfam: Glycine rich protein [PF12810.9, score=31.6]} {RNA1509_28009} {RNA1310_17226} {RNA815_32720}
72. MligTC455_53549 782 16.29 Mlig455_059223

Neo: -

Age: Down-Down-Up

SIDT1 1.698 - - 0.722 - 0.976 - Mlig455_059223 {REF} {Length: 3659} {TRANSSPLICED} {Pfam: dsRNA-gated channel SID-1 [PF13965.8, score=293.6]} {Human: ENSG00000072858, SIDT1, SID1 transmembrane family member 1, [Score=169, Expect=2e-42]} {Mouse: ENSMUSG00000022696, Sidt1, SID1 transmembrane family, member 1, [Score=158, Expect=4e-39]; ENSMUSG00000034908, Sidt2, SID1 transmembrane family, member 2, [Score=154, Expect=7e-38]} {Celegans: WBGene00006477, chup-1, CHolesterol UPtake associated, [Score=118, Expect=6e-27]} {Smed: dd_Smed_v6_6063_0_2, dd_Smed_v6_6063_0_2, [Score=162, Expect=7e-41]} {RNA1509_26791} {RNA1310_31149.1} {RNA815_1905}
73. MligTC455_51199 206 4.29 Mlig455_044015

Neo: -

Age: Down-Up-Down

ARX 1.697 - - 0.730 - 0.967 - Mlig455_044015 {REF} {Length: 1926} {Pfam: Homeodomain [PF00046.31, score=85.3]} {Human: ENSG00000004848, ARX, aristaless related homeobox, [Score=116, Expect=8e-30]} {Mouse: ENSMUSG00000035277, Arx, aristaless related homeobox, [Score=115, Expect=1e-29]} {Dmel: FBgn0008636, hbn, homeobrain, [Score=128, Expect=5e-35]} {Celegans: WBGene00000433, ceh-8, Homeobox protein ceh-8, [RH, Score=103, Expect=6e-27]} {Smed: dd_Smed_v6_16955_0_1, dd_Smed_v6_16955_0_1, [Score=105, Expect=9e-27]} {RNA1509_46102} {RNA1310_37906, RNA1509_46102}
74. MligTC455_16415 197 4.1 Mlig455_000401

Neo: -

Age: -

Region-enriched R2: 4.276/0.00982

ROR1 1.691 - - 0.733 - 0.958 - Mlig455_000401 {REF} {Length: 3780} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=233.3]; Protein kinase domain [PF00069.27, score=85.9]; Immunoglobulin I-set domain [PF07679.18, score=49.4]; Immunoglobulin domain [PF13927.8, score=46.6]; Immunoglobulin domain [PF00047.27, score=31.9]; Immunoglobulin domain [PF13895.8, score=30.0]; Fz domain [PF01392.24, score=27.6]; Kringle domain [PF00051.20, score=22.3]; Immunoglobulin V-set domain [PF07686.19, score=19.5]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [RH, Score=390, Expect=1e-119]; ENSG00000169071, ROR2, receptor tyrosine kinase like orphan receptor 2, [RH, Score=379, Expect=1e-115]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [RH, Score=386, Expect=1e-118]; ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [RH, Score=377, Expect=4e-115]} {Dmel: FBgn0010407, Ror, [Score=286, Expect=3e-84]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=285, Expect=4e-82]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [RH, Score=439, Expect=2e-139]} {RNA1509_35395} {RNA1310_13558, RNA1509_35395} {RNA1509_35395, RNA815_27446}
75. MligTC455_05889 28 0.58 Mlig455_027604, Mlig455_047689, Mlig455_047690

Neo: -

Age: -

TLR4 1.689 - - - 0.724 0.965 -

Mlig455_027604 {REF} {Length: 3445} {Pfam: Leucine rich repeat [PF13855.8, score=68.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=38.2]; TIR domain [PF01582.22, score=31.9]; TIR domain [PF13676.8, score=24.5]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=21.4]} {Human: ENSG00000136869, TLR4, toll like receptor 4, [RH, Score=74.3, Expect=6e-13]} {Mouse: ENSMUSG00000031558, Slit2, slit guidance ligand 2, [Score=60.1, Expect=1e-08]; ENSMUSG00000030600, Lrfn1, leucine rich repeat and fibronectin type III domain containing 1, [Score=59.3, Expect=2e-08]; ENSMUSG00000056427, Slit3, slit guidance ligand 3, [Score=58.5, Expect=4e-08]} {Dmel: FBgn0036494, Toll-6, [Score=80.5, Expect=4e-15]} {Celegans: WBGene00006593, tol-1, TOLl (Drosophila) family, [Score=50.4, Expect=6e-06]} {RNA1310_7084} {RNA815_22808}

Mlig455_047689 {REF} {Length: 352} {Pfam: Leucine rich repeat [PF13855.8, score=35.5]; Leucine Rich repeats (2 copies) [PF12799.9, score=20.6]} {RNA1310_7084} {RNA815_47088}

Mlig455_047690 {REF} {Length: 346} {Pfam: Leucine rich repeat [PF13855.8, score=68.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=38.2]; TIR domain [PF01582.22, score=31.9]; TIR domain [PF13676.8, score=24.5]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=21.4]} {Human: ENSG00000136869, TLR4, toll like receptor 4, [RH, Score=74.3, Expect=6e-13]} {Mouse: ENSMUSG00000031558, Slit2, slit guidance ligand 2, [Score=60.1, Expect=1e-08]; ENSMUSG00000030600, Lrfn1, leucine rich repeat and fibronectin type III domain containing 1, [Score=59.3, Expect=2e-08]; ENSMUSG00000056427, Slit3, slit guidance ligand 3, [Score=58.5, Expect=4e-08]} {Dmel: FBgn0036494, Toll-6, [Score=80.5, Expect=4e-15]} {Celegans: WBGene00006593, tol-1, TOLl (Drosophila) family, [Score=50.4, Expect=6e-06]} {RNA1310_7084} {RNA815_47699}
76. MligTC455_40270 49 1.03 Mlig455_002977

Neo: -

Age: Down-Up-Down

Region-enriched R2: 7.640/0.00158

AGAP1 1.689 - - - 0.952 0.737 - Mlig455_002977 {REF} {Length: 2591} {Pfam: Ras family [PF00071.24, score=40.1]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=21.9]} {Human: ENSG00000157985, AGAP1, ArfGAP with GTPase domain, ankyrin repeat and PH domain 1, [Score=253, Expect=3e-81]; ENSG00000133612, AGAP3, ArfGAP with GTPase domain, ankyrin repeat and PH domain 3, [Score=243, Expect=2e-77]} {Mouse: ENSMUSG00000055013, Agap1, ArfGAP with GTPase domain, ankyrin repeat and PH domain 1, [Score=253, Expect=2e-77]; ENSMUSG00000023353, Agap3, ArfGAP with GTPase domain, ankyrin repeat and PH domain 3, [Score=243, Expect=2e-77]} {Dmel: FBgn0028509, CenG1A, Centaurin gamma 1A, [Score=251, Expect=7e-76]} {Celegans: WBGene00000566, cnt-2, Arf-GAP with ANK repeat and PH domain-containing protein cnt-2, [Score=205, Expect=2e-59]} {Smed: dd_Smed_v6_4301_0_1, dd_Smed_v6_4301_0_1, [Score=232, Expect=7e-73]} {RNA1509_22773} {RNA1310_2370} {RNA815_11138}
77. MligTC455_28457 1836 38.25 Mlig455_047188, Mlig455_048490

Neo: -

Age: logFC(26M/2M)=-0.228

RSPH10B2 1.681 - - 0.729 - 0.952 -

Mlig455_047188 {REF} {Length: 3292} {TRANSSPLICED} {Pfam: MORN repeat [PF02493.22, score=169.8]} {Human: ENSG00000169402, RSPH10B2, radial spoke head 10 homolog B2, [RH, Score=435, Expect=9e-137]; ENSG00000155026, RSPH10B, radial spoke head 10 homolog B, [RH, Score=431, Expect=3e-135]} {Mouse: ENSMUSG00000075569, Rsph10b, radial spoke head 10 homolog B (Chlamydomonas), [RH, Score=435, Expect=5e-137]} {Dmel: FBgn0050429, CG30429, [Score=88.2, Expect=1e-18]} {Celegans: WBGene00002179, jph-1, JunctoPHilin, [Score=77.0, Expect=4e-14]} {Smed: dd_Smed_v6_12762_0_1, dd_Smed_v6_12762_0_1, [RH, Score=524, Expect=5e-171]} {RNA1509_2912} {RNA1310_4817} {RNA815_4683.1}

Mlig455_048490 {REF} {Length: 3647} {TRANSSPLICED} {Pfam: MORN repeat [PF02493.22, score=169.8]} {Human: ENSG00000169402, RSPH10B2, radial spoke head 10 homolog B2, [RH, Score=434, Expect=2e-136]; ENSG00000155026, RSPH10B, radial spoke head 10 homolog B, [RH, Score=429, Expect=1e-134]} {Mouse: ENSMUSG00000075569, Rsph10b, radial spoke head 10 homolog B (Chlamydomonas), [RH, Score=434, Expect=2e-136]} {Dmel: FBgn0050429, CG30429, [Score=88.2, Expect=1e-18]} {Celegans: WBGene00002179, jph-1, JunctoPHilin, [Score=77.0, Expect=4e-14]} {Smed: dd_Smed_v6_12762_0_1, dd_Smed_v6_12762_0_1, [RH, Score=525, Expect=1e-171]} {RNA1509_2912} {RNA1310_4817, RNA1509_2912} {RNA1509_2912, RNA815_4683.1}
78. MligTC455_17562 108 2.25 Mlig455_022496

Neo: -

Age: -

NECAB3 1.677 - - - 0.976 0.701 - Mlig455_022496 {REF} {Length: 1499} {Pfam: EF hand [PF00036.34, score=34.0]; EF-hand domain [PF13405.8, score=33.4]; EF-hand domain pair [PF13833.8, score=29.2]; EF-hand domain pair [PF13499.8, score=28.3]; Antibiotic biosynthesis monooxygenase [PF03992.18, score=22.0]; EF hand [PF13202.8, score=21.3]} {Human: ENSG00000125967, NECAB3, N-terminal EF-hand calcium binding protein 3, [RH, Score=189, Expect=7e-57]; ENSG00000123119, NECAB1, N-terminal EF-hand calcium binding protein 1, [RH, Score=186, Expect=1e-55]} {Mouse: ENSMUSG00000040536, Necab1, N-terminal EF-hand calcium binding protein 1, [RH, Score=191, Expect=7e-58]; ENSMUSG00000027489, Necab3, N-terminal EF-hand calcium binding protein 3, [RH, Score=191, Expect=9e-58]} {RNA1509_46831} {RNA1310_24461} {RNA815_25216}
79. MligTC455_53844 1403 29.24 Mlig455_051626

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.540

1.677 - - - 0.703 0.974 - Mlig455_051626 {REF} {Length: 1671} {RNA1509_15580} {RNA1310_24090} {RNA815_10676.2}
80. MligTC455_44862 1318 27.47 Mlig455_028792

Neo: -

Age: -

Region-enriched R2: 3.389/0.00000

QPCT 1.671 - - - 0.966 0.705 - Mlig455_028792 {REF} {Length: 1901} {Pfam: Peptidase family M28 [PF04389.19, score=137.7]} {Human: ENSG00000115828, QPCT, glutaminyl-peptide cyclotransferase, [RH, Score=189, Expect=5e-57]; ENSG00000011478, QPCTL, glutaminyl-peptide cyclotransferase like, [RH, Score=186, Expect=1e-55]} {Mouse: ENSMUSG00000030407, Qpctl, glutaminyl-peptide cyclotransferase-like, [RH, Score=190, Expect=3e-57]; ENSMUSG00000024084, Qpct, glutaminyl-peptide cyclotransferase (glutaminyl cyclase), [RH, Score=189, Expect=5e-57]} {Dmel: FBgn0036999, isoQC, iso Glutaminyl cyclase, [RH, Score=210, Expect=2e-65]} {Celegans: WBGene00010418, H27A22.1, [Score=182, Expect=5e-55]} {Smed: dd_Smed_v6_4861_0_2, dd_Smed_v6_4861_0_2, [Score=166, Expect=1e-48]} {RNA1509_15042, RNA1509_18145} {RNA1310_21749, RNA1509_15042, RNA1509_18145} {RNA1509_15042, RNA1509_18145, RNA815_8635.1}
81. MligTC455_33841 898 18.71 Mlig455_004818, Mlig455_004886

Neo: -

Age: logFC(26M/2M)=-0.301

Region-enriched R2: 1.729/0.00165

CDKL1 1.668 - - 0.715 - 0.953 -

Mlig455_004818 {REF} {Length: 2858} {Pfam: Protein kinase domain [PF00069.27, score=245.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=115.2]; RIO1 family [PF01163.24, score=22.4]; Haspin like kinase domain [PF12330.10, score=17.8]} {Human: ENSG00000100490, CDKL1, cyclin dependent kinase like 1, [RH, Score=427, Expect=2e-147]; ENSG00000205111, CDKL4, cyclin dependent kinase like 4, [RH, Score=422, Expect=4e-145]} {Mouse: ENSMUSG00000020990, Cdkl1, cyclin-dependent kinase-like 1 (CDC2-related kinase), [RH, Score=430, Expect=6e-149]; ENSMUSG00000033966, Cdkl4, cyclin-dependent kinase-like 4, [RH, Score=421, Expect=1e-145]} {Dmel: FBgn0031730, CG7236, [RH, Score=379, Expect=7e-128]} {Celegans: WBGene00012779, cdkl-1, Cyclin-Dependent Kinase-Like, [RH, Score=395, Expect=1e-133]} {Smed: dd_Smed_v6_9353_0_1, dd_Smed_v6_9353_0_1, [RH, Score=478, Expect=1e-167]} {RNA1509_19679} {RNA1310_6686.2} {RNA815_5397}

Mlig455_004886 {REF} {Length: 2943} {Pfam: Protein kinase domain [PF00069.27, score=245.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=115.0]; RIO1 family [PF01163.24, score=22.4]; Haspin like kinase domain [PF12330.10, score=17.8]; ABC1 atypical kinase-like domain [PF03109.18, score=17.7]} {Human: ENSG00000100490, CDKL1, cyclin dependent kinase like 1, [RH, Score=428, Expect=6e-148]; ENSG00000205111, CDKL4, cyclin dependent kinase like 4, [RH, Score=422, Expect=4e-146]} {Mouse: ENSMUSG00000020990, Cdkl1, cyclin-dependent kinase-like 1 (CDC2-related kinase), [RH, Score=431, Expect=2e-149]; ENSMUSG00000033966, Cdkl4, cyclin-dependent kinase-like 4, [RH, Score=422, Expect=6e-146]} {Dmel: FBgn0031730, CG7236, [RH, Score=380, Expect=3e-128]} {Celegans: WBGene00012779, cdkl-1, Cyclin-Dependent Kinase-Like, [RH, Score=392, Expect=2e-132]} {Smed: dd_Smed_v6_9353_0_1, dd_Smed_v6_9353_0_1, [RH, Score=479, Expect=5e-168]} {RNA1509_19679} {RNA1310_6686.2} {RNA815_5397}
82. MligTC455_38355 110 2.29 Mlig455_039715, Mlig455_039769

Neo: -

Age: -

KCNB2 1.668 - - - 0.966 - 0.702

Mlig455_039715 {REF} {Length: 3883} {Pfam: Ion transport protein [PF00520.33, score=114.4]; BTB/POZ domain [PF02214.24, score=75.0]; Ion channel [PF07885.18, score=43.6]} {Human: ENSG00000182674, KCNB2, potassium voltage-gated channel subfamily B member 2, [Score=218, Expect=3e-60]; ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [Score=213, Expect=2e-60]; ENSG00000158445, KCNB1, potassium voltage-gated channel subfamily B member 1, [Score=213, Expect=7e-59]; ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=210, Expect=2e-59]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [Score=209, Expect=7e-59]} {Mouse: ENSMUSG00000092083, Kcnb2, potassium voltage gated channel, Shab-related subfamily, member 2, [Score=219, Expect=5e-61]; ENSMUSG00000050556, Kcnb1, potassium voltage gated channel, Shab-related subfamily, member 1, [Score=218, Expect=1e-60]; ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [Score=214, Expect=8e-61]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=213, Expect=6e-60]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=230, Expect=8e-67]} {Celegans: WBGene00008819, shw-1, SHaW family of potassium channels, [Score=236, Expect=3e-69]} {Smed: dd_Smed_v6_11886_0_1, dd_Smed_v6_11886_0_1, [RH, Score=592, Expect=0.0]} {RNA1509_22940} {RNA1310_17926} {RNA815_8687.1}

Mlig455_039769 {REF} {Length: 4176} {Pfam: Ion transport protein [PF00520.33, score=116.7]; BTB/POZ domain [PF02214.24, score=75.0]; Ion channel [PF07885.18, score=43.6]; Polycystin cation channel [PF08016.14, score=20.7]} {Human: ENSG00000182674, KCNB2, potassium voltage-gated channel subfamily B member 2, [Score=219, Expect=8e-61]; ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [Score=216, Expect=2e-61]; ENSG00000158445, KCNB1, potassium voltage-gated channel subfamily B member 1, [Score=215, Expect=2e-59]; ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=213, Expect=2e-60]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [Score=213, Expect=4e-60]; ENSG00000131398, KCNC3, potassium voltage-gated channel subfamily C member 3, [Score=210, Expect=4e-58]} {Mouse: ENSMUSG00000092083, Kcnb2, potassium voltage gated channel, Shab-related subfamily, member 2, [Score=221, Expect=2e-61]; ENSMUSG00000050556, Kcnb1, potassium voltage gated channel, Shab-related subfamily, member 1, [Score=219, Expect=4e-61]; ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [Score=216, Expect=6e-62]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=215, Expect=6e-61]; ENSMUSG00000062785, Kcnc3, potassium voltage gated channel, Shaw-related subfamily, member 3, [Score=211, Expect=1e-58]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=231, Expect=2e-67]} {Celegans: WBGene00008819, shw-1, SHaW family of potassium channels, [Score=239, Expect=2e-70]} {Smed: dd_Smed_v6_11886_0_1, dd_Smed_v6_11886_0_1, [RH, Score=595, Expect=0.0]} {RNA1509_22940} {RNA1310_17926} {RNA815_8687.1}
83. MligTC455_25588 1046 21.8 Mlig455_029794

Neo: -

Age: -

Region-enriched R2: 2.896/0.00002

1.667 - - 0.713 - 0.954 - Mlig455_029794 {REF} {Length: 1354} {Pfam: Domain of unknown function (DUF4573) [PF15140.8, score=40.1]; Domain of unknown function (DUF1848) [PF08902.13, score=20.8]} {RNA1509_17753} {RNA1310_70608} {RNA815_1498.1}
84. MligTC455_38368 107 2.24 Mlig455_026435, Mlig455_044757

Neo: -

Age: Up-Down-Down

SSUH2 1.664 - - - - 0.955 0.709

Mlig455_026435 {REF} {Length: 1789} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [RH, Score=233, Expect=1e-72]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [RH, Score=195, Expect=1e-58]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=117, Expect=3e-29]} {RNA1509_6425} {RNA1310_32434} {RNA815_16161}

Mlig455_044757 {REF} {Length: 883} {TRANSSPLICED} {RNA1509_28356} {RNA1310_61125} {RNA815_53103}
85. MligTC455_41342 7570 157.7 Mlig455_028402, Mlig455_028415, Mlig455_028437

Neo: -

Age: logFC(26M/2M)=-0.192

MORN3 1.662 - - - 0.712 0.950 -

Mlig455_028402 {REF} {Length: 1268} {TRANSSPLICED} {Pfam: MORN repeat [PF02493.22, score=98.7]} {Human: ENSG00000139714, MORN3, MORN repeat containing 3, [RH, Score=258, Expect=1e-86]; ENSG00000285371, MORN3, MORN repeat containing 3, [RH, Score=258, Expect=1e-86]} {Mouse: ENSMUSG00000029477, Morn3, MORN repeat containing 3, [RH, Score=258, Expect=8e-87]} {Dmel: FBgn0050429, CG30429, [RH, Score=115, Expect=2e-30]} {Smed: dd_Smed_v6_3784_0_1, dd_Smed_v6_3784_0_1, [RH, Score=258, Expect=4e-87]} {RNA1509_4357} {RNA1310_26142, RNA1509_4357} {RNA1509_4357, RNA815_11911.1}

Mlig455_028415 {REF} {Length: 1243} {TRANSSPLICED} {Pfam: MORN repeat [PF02493.22, score=98.7]} {Human: ENSG00000139714, MORN3, MORN repeat containing 3, [RH, Score=255, Expect=2e-85]; ENSG00000285371, MORN3, MORN repeat containing 3, [RH, Score=255, Expect=2e-85]} {Mouse: ENSMUSG00000029477, Morn3, MORN repeat containing 3, [RH, Score=256, Expect=5e-86]} {Dmel: FBgn0050429, CG30429, [RH, Score=112, Expect=4e-29]} {Smed: dd_Smed_v6_3784_0_1, dd_Smed_v6_3784_0_1, [RH, Score=255, Expect=7e-86]} {RNA1509_30838, RNA1509_32244} {RNA1310_27343, RNA1509_32244} {RNA1509_32244, RNA815_11911.2}

Mlig455_028437 {REF} {Length: 1242} {TRANSSPLICED} {Pfam: MORN repeat [PF02493.22, score=98.7]} {Human: ENSG00000139714, MORN3, MORN repeat containing 3, [RH, Score=254, Expect=2e-85]; ENSG00000285371, MORN3, MORN repeat containing 3, [RH, Score=254, Expect=2e-85]} {Mouse: ENSMUSG00000029477, Morn3, MORN repeat containing 3, [RH, Score=256, Expect=8e-86]} {Dmel: FBgn0050429, CG30429, [RH, Score=111, Expect=4e-29]} {Smed: dd_Smed_v6_3784_0_1, dd_Smed_v6_3784_0_1, [RH, Score=254, Expect=1e-85]} {RNA1509_30838, RNA1509_35025} {RNA1310_27343, RNA1509_30838, RNA1509_35025} {RNA1509_30838, RNA1509_35025, RNA815_11911.2}
86. MligTC455_12579 69 1.44 Mlig455_039084

Neo: -

Age: Down-Up-Down

LRCH3 0.993 - - - - 0.993 - Mlig455_039084 {REF} {Length: 1924} {Pfam: Leucine rich repeat [PF13855.8, score=68.3]; Leucine Rich repeats (2 copies) [PF12799.9, score=47.2]} {Human: ENSG00000186001, LRCH3, leucine rich repeats and calponin homology domain containing 3, [RH, Score=162, Expect=4e-42]; ENSG00000136141, LRCH1, leucine rich repeats and calponin homology domain containing 1, [RH, Score=155, Expect=5e-40]} {Mouse: ENSMUSG00000022801, Lrch3, leucine-rich repeats and calponin homology (CH) domain containing 3, [RH, Score=162, Expect=2e-42]; ENSMUSG00000068015, Lrch1, leucine-rich repeats and calponin homology (CH) domain containing 1, [RH, Score=154, Expect=6e-40]} {Dmel: FBgn0032633, Lrch, Leucine-rich-repeats and calponin homology domain protein, [RH, Score=145, Expect=9e-37]} {Celegans: WBGene00022759, ZK546.2, [Score=72.8, Expect=3e-14]} {Smed: dd_Smed_v6_12270_0_1, dd_Smed_v6_12270_0_1, [RH, Score=119, Expect=3e-28]} {RNA1509_38422} {RNA1310_15035.1} {RNA815_5934}
87. MligTC455_15765 194 4.05 Mlig455_007606

Neo: -

Age: -

0.984 - - - 0.984 - - Mlig455_007606 {REF} {Length: 1349} {RNA1310_25770.1} {RNA815_11095}
88. MligTC455_34318 1984 41.33 Mlig455_058813

Neo: -

Age: -

MSI2 0.983 - - - - 0.983 - Mlig455_058813 {REF} {Length: 3382} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=113.4]; RNA recognition motif [PF16367.7, score=38.9]; Nup53/35/40-type RNA recognition motif [PF14605.8, score=19.3]} {Human: ENSG00000153944, MSI2, musashi RNA binding protein 2, [RH, Score=252, Expect=2e-81]; ENSG00000135097, MSI1, musashi RNA binding protein 1, [RH, Score=245, Expect=2e-78]} {Mouse: ENSMUSG00000069769, Msi2, musashi RNA-binding protein 2, [RH, Score=252, Expect=1e-81]; ENSMUSG00000054256, Msi1, musashi RNA-binding protein 1, [RH, Score=244, Expect=3e-78]} {Dmel: FBgn0260943, Rbp6, RNA-binding protein 6, [RH, Score=251, Expect=2e-79]} {Celegans: WBGene00003423, msi-1, MuSashI (Fly neural) family; Neural RNA-binding protein MSI-1, [RH, Score=249, Expect=3e-81]} {Smed: dd_Smed_v6_8902_0_1, dd_Smed_v6_8902_0_1, [RH, Score=283, Expect=1e-92]} {RNA1509_2174} {RNA1310_11614, RNA1509_2174} {RNA1509_2174, RNA815_1264}
89. MligTC455_49690 72 1.5 Mlig455_068367

Neo: -

Age: Down-Down-Up

0.981 - - - - 0.981 - Mlig455_068367 {REF} {Length: 1546} {Smed: dd_Smed_v6_8297_0_1, dd_Smed_v6_8297_0_1, [RH, Score=53.1, Expect=2e-09]} {RNA1509_38073} {RNA1310_34998} {RNA815_20391}
90. MligTC455_37863 213 4.44 Mlig455_015363

Neo: -

Age: Up-Down-Down

NBAS 0.98 - - 0.980 - - - Mlig455_015363 {REF} {Length: 8517} {TRANSSPLICED} {Pfam: Secretory pathway protein Sec39 [PF08314.13, score=51.4]; Neuroblastoma-amplified sequence, N terminal [PF15492.8, score=33.5]} {Human: ENSG00000151779, NBAS, neuroblastoma amplified sequence, [RH, Score=384, Expect=1e-106]} {Mouse: ENSMUSG00000020576, Nbas, neuroblastoma amplified sequence, [RH, Score=413, Expect=6e-116]} {Celegans: WBGene00008990, smgl-1, [RH, Score=55.5, Expect=5e-07]} {Smed: dd_Smed_v6_7998_0_1, dd_Smed_v6_7998_0_1, [RH, Score=206, Expect=1e-52]} {RNA1509_11685, RNA1509_55641} {RNA1310_353.1, RNA1509_11685, RNA1509_55641} {RNA1509_11685, RNA1509_55641, RNA815_138}
91. MligTC455_03696 75 1.57 Mlig455_007008

Neo: -

Age: -

CACNA1H 0.979 - - - - 0.979 - Mlig455_007008 {REF} {Length: 6530} {Pfam: Ion transport protein [PF00520.33, score=430.6]; Polycystin cation channel [PF08016.14, score=56.2]} {Human: ENSG00000196557, CACNA1H, calcium voltage-gated channel subunit alpha1 H, [Score=836, Expect=0.0]} {Mouse: ENSMUSG00000024112, Cacna1h, calcium channel, voltage-dependent, T type, alpha 1H subunit, [Score=838, Expect=0.0]} {Dmel: FBgn0264386, Ca-alpha1T, Ca[2+]-channel protein alpha[[1]] subunit T, [RH, Score=857, Expect=0.0]} {Celegans: WBGene00000367, cca-1, Voltage-dependent T-type calcium channel subunit alpha, [RH, Score=761, Expect=0.0]} {Smed: dd_Smed_v6_16822_0_1, dd_Smed_v6_16822_0_1, [RH, Score=916, Expect=0.0]} {RNA1509_28376} {RNA1310_9083} {RNA815_21869}
92. MligTC455_12995 20 0.42 Mlig455_009321

Neo: -

Age: -

0.979 - - - - 0.979 - Mlig455_009321 {REF} {Length: 1435} {Smed: dd_Smed_v6_14929_0_1, dd_Smed_v6_14929_0_1, [Score=52.4, Expect=8e-09]} {RNA1509_58376} {RNA1310_18479.1} {RNA815_35714.2}
93. MligTC455_01275 8 0.17 Mlig455_032255

Neo: Germline

Age: -

0.978 - - - - 0.978 - Mlig455_032255 {REF} {Length: 1275}
94. MligTC455_48520 46 0.96 Mlig455_004433

Neo: -

Age: -

0.978 - - - 0.978 - - Mlig455_004433 {REF} {Length: 701} {RNA1310_56623} {RNA815_27009}
95. MligTC455_09221 30 0.62 Mlig455_017881

Neo: -

Age: -

0.977 - - - 0.977 - - Mlig455_017881 {REF} {Length: 792} {NoTransDecoderORF} {RNA1310_97207} {RNA815_52780}
96. MligTC455_02400 23 0.48 Mlig455_023463

Neo: -

Age: -

0.976 - - - - 0.976 - Mlig455_023463 {REF} {Length: 1638} {RNA1509_45548} {RNA1310_99427} {RNA815_60916}
97. MligTC455_44339 100 2.08 Mlig455_001551

Neo: -

Age: -

GPR158 0.976 - - - 0.976 - - Mlig455_001551 {REF} {Length: 3428} {Pfam: 7 transmembrane sweet-taste receptor of 3 GCPR [PF00003.24, score=94.6]} {Human: ENSG00000151025, GPR158, G protein-coupled receptor 158, [RH, Score=246, Expect=6e-68]; ENSG00000276469, GPR179, G protein-coupled receptor 179, [RH, Score=240, Expect=2e-65]; ENSG00000277399, GPR179, G protein-coupled receptor 179, [RH, Score=234, Expect=2e-63]} {Mouse: ENSMUSG00000070337, Gpr179, G protein-coupled receptor 179, [RH, Score=253, Expect=6e-70]; ENSMUSG00000045967, Gpr158, G protein-coupled receptor 158, [RH, Score=251, Expect=8e-70]} {Dmel: FBgn0051660, smog, [RH, Score=293, Expect=1e-85]} {Celegans: WBGene00009558, F39B2.8, [Score=194, Expect=8e-53]} {Smed: dd_Smed_v6_8408_0_1, dd_Smed_v6_8408_0_1, [RH, Score=359, Expect=1e-112]} {RNA1509_37699} {RNA1310_6430} {RNA815_19661}
98. MligTC455_40501 68 1.42 Mlig455_011503

Neo: -

Age: Up-Down-Down

SPATA18 0.975 - - - - 0.975 - Mlig455_011503 {REF} {Length: 3947} {Pfam: Mitochondria-eating protein [PF16026.7, score=151.5]} {Human: ENSG00000163071, SPATA18, spermatogenesis associated 18, [Score=174, Expect=2e-47]} {Mouse: ENSMUSG00000029155, Spata18, spermatogenesis associated 18, [Score=174, Expect=4e-48]} {Smed: dd_Smed_v6_6321_0_1, dd_Smed_v6_6321_0_1, [Score=196, Expect=7e-56]} {RNA1509_30652} {RNA1310_42425} {RNA815_16227}
99. MligTC455_45731 76 1.59 Mlig455_003947, Mlig455_003964, Mlig455_005981

Neo: -

Age: Up-Down-Down

TTLL7 0.975 - - - 0.975 - -

Mlig455_003947 {REF} {Length: 4060} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=212.9]; Sugar-transfer associated ATP-grasp [PF14397.8, score=23.9]; YheC/D like ATP-grasp [PF14398.8, score=21.3]} {Human: ENSG00000137941, TTLL7, tubulin tyrosine ligase like 7, [Score=351, Expect=4e-107]} {Mouse: ENSMUSG00000036745, Ttll7, tubulin tyrosine ligase-like family, member 7, [Score=347, Expect=1e-103]} {Dmel: FBgn0039501, CG5987, [Score=235, Expect=3e-65]} {Celegans: WBGene00019230, ttll-11, Tubulin Tyrosine Ligase Like, [Score=158, Expect=4e-40]} {Smed: dd_Smed_v6_13600_0_1, dd_Smed_v6_13600_0_1, [Score=313, Expect=3e-91]} {RNA1310_17573} {RNA815_57268}

Mlig455_003964 {REF} {Length: 3783} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=213.2]; Sugar-transfer associated ATP-grasp [PF14397.8, score=23.9]; YheC/D like ATP-grasp [PF14398.8, score=21.3]} {Human: ENSG00000137941, TTLL7, tubulin tyrosine ligase like 7, [Score=353, Expect=2e-109]} {Mouse: ENSMUSG00000036745, Ttll7, tubulin tyrosine ligase-like family, member 7, [Score=349, Expect=2e-104]} {Dmel: FBgn0039501, CG5987, [Score=234, Expect=4e-65]} {Celegans: WBGene00019230, ttll-11, Tubulin Tyrosine Ligase Like, [Score=157, Expect=7e-40]} {Smed: dd_Smed_v6_13600_0_1, dd_Smed_v6_13600_0_1, [Score=312, Expect=4e-91]} {RNA1310_17573} {RNA815_57268}

Mlig455_005981 {REF} {Length: 4222} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=213.3]; Sugar-transfer associated ATP-grasp [PF14397.8, score=23.7]; YheC/D like ATP-grasp [PF14398.8, score=21.1]} {Human: ENSG00000137941, TTLL7, tubulin tyrosine ligase like 7, [Score=353, Expect=2e-107]} {Mouse: ENSMUSG00000036745, Ttll7, tubulin tyrosine ligase-like family, member 7, [Score=349, Expect=9e-104]} {Dmel: FBgn0039501, CG5987, [Score=235, Expect=5e-65]} {Celegans: WBGene00019230, ttll-11, Tubulin Tyrosine Ligase Like, [Score=157, Expect=9e-40]} {Smed: dd_Smed_v6_13600_0_1, dd_Smed_v6_13600_0_1, [Score=314, Expect=3e-91]} {RNA1310_17573} {RNA815_57268}
100. MligTC455_29797 2469 51.44 Mlig455_011428

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.328

Region-enriched R2: 5.791/0.00000
Region-enriched R3: 3.237/0.00612

0.974 - - - 0.974 - - Mlig455_011428 {REF} {Length: 902} {RNA1509_21417, RNA1509_23190, RNA1509_31800, RNA1509_3881, RNA1509_41776, RNA1509_43586} {RNA1310_44752, RNA1509_21417, RNA1509_23190, RNA1509_31800, RNA1509_3881, RNA1509_41776, RNA1509_43586} {RNA1509_21417, RNA1509_23190, RNA1509_31800, RNA1509_3881, RNA1509_41776, RNA1509_43586, RNA815_21540}

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