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Results for MligTC455_25588

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_25588 1046 21.80 Mlig455_029794

Neo: -

Age: -

Region-enriched R2: 2.896/0.00002

Mlig455_029794 {REF} {Length: 1354} {Pfam: Domain of unknown function (DUF4573) [PF15140.8, score=40.1]; Domain of unknown function (DUF1848) [PF08902.13, score=20.8]} {RNA1509_17753} {RNA1310_70608} {RNA815_1498.1}

Cumulative graph for MligTC455_25588

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.271 4.427 0.36647 1.00000
RegionR2 2.896 4.427 0.00000 0.00002
RegionR3 0.783 4.427 0.11283 0.58468
RegionR4 -1.068 4.427 0.11536 0.33813
RegionR5 -1.924 4.427 0.00198 0.01733
RegionR6 -1.421 4.427 0.02426 0.28365
RegionR7 0.811 4.427 0.17643 0.77048
RegionR8 1.194 4.427 0.08572 0.55490

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 1.775 4.427 0.26432 0.96972
RegenerationR2 -0.194 4.427 0.69662 0.95507
RegenerationR3 -1.12 4.427 0.05214 0.39453
RegenerationR4 -0.411 4.427 0.52840 0.88358
RegenerationR5 -0.664 4.427 0.35967 0.77105
RegenerationR6 0.158 4.427 0.81725 0.98577
RegenerationBL -1.259 4.427 0.07946 0.32930
RegenerationTP -0.897 4.427 0.17725 0.61176


Genes with expression patterns similar to MligTC455_25588

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_25588 1046 21.8 Mlig455_029794

Neo: -

Age: -

Region-enriched R2: 2.896/0.00002

6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_029794 {REF} {Length: 1354} {Pfam: Domain of unknown function (DUF4573) [PF15140.8, score=40.1]; Domain of unknown function (DUF1848) [PF08902.13, score=20.8]} {RNA1509_17753} {RNA1310_70608} {RNA815_1498.1}
2. MligTC455_44050 2086 43.46 Mlig455_028045, Mlig455_028051

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.242

Region-specific R2: 6.161

Region-enriched R2: 7.072/0.00000
Region-enriched R3: 3.149/0.00025

5.469 0.909 0.746 0.932 0.930 0.961 0.991

Mlig455_028045 {REF} {Length: 1156} {RNA1509_31459, RNA1509_3903} {RNA1310_2730.2, RNA1509_31459, RNA1509_3903} {RNA1509_31459, RNA1509_3903, RNA815_7682}

Mlig455_028051 {REF} {Length: 871} {NoTransDecoderORF} {RNA1509_3903} {RNA1310_15260} {RNA815_7682}
3. MligTC455_26766 638 13.3 Mlig455_017977

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.360

Region-enriched R2: 3.395/0.00052

4.958 0.760 0.728 0.852 0.836 0.993 0.789 Mlig455_017977 {REF} {Length: 2516} {Smed: dd_Smed_v6_10627_0_1, dd_Smed_v6_10627_0_1, [Score=249, Expect=3e-71]} {RNA1509_19813} {RNA1310_621} {RNA815_183.1}
4. MligTC455_26765 686 14.29 Mlig455_006971

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.201/0.00046

4.873 0.770 0.726 0.764 0.832 0.993 0.788 Mlig455_006971 {REF} {Length: 6360} {Pfam: Cadherin domain [PF00028.19, score=29.2]} {Smed: dd_Smed_v6_10627_0_1, dd_Smed_v6_10627_0_1, [RH, Score=328, Expect=1e-93]} {RNA1509_19813, RNA1509_5311} {RNA1310_621, RNA1509_19813, RNA1509_5311} {RNA1509_19813, RNA1509_5311, RNA815_183.1}
5. MligTC455_03841 920 19.16 Mlig455_018790, Mlig455_048140

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.474

Region-enriched R2: 5.915/0.00081

NKX2-1, NKX2-4 4.467 0.854 0.771 0.887 - 0.995 0.960

Mlig455_018790 {REF} {Length: 2203} {Pfam: Homeodomain [PF00046.31, score=72.7]} {Human: ENSG00000136352, NKX2-1, NK2 homeobox 1, [RH, Score=145, Expect=2e-39]; ENSG00000125816, NKX2-4, NK2 homeobox 4, [RH, Score=145, Expect=2e-39]} {Mouse: ENSMUSG00000001496, Nkx2-1, NK2 homeobox 1, [RH, Score=145, Expect=2e-39]} {Dmel: FBgn0028993, scro, scarecrow, [RH, Score=166, Expect=8e-47]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [RH, Score=134, Expect=2e-36]} {Smed: dd_Smed_v6_6729_0_1, dd_Smed_v6_6729_0_1, [RH, Score=191, Expect=1e-57]} {RNA1509_12761} {RNA1310_13401} {RNA815_21584}

Mlig455_048140 {REF} {Length: 2218} {Pfam: Homeodomain [PF00046.31, score=72.5]} {Human: ENSG00000125816, NKX2-4, NK2 homeobox 4, [RH, Score=145, Expect=3e-39]; ENSG00000136352, NKX2-1, NK2 homeobox 1, [RH, Score=145, Expect=7e-39]} {Mouse: ENSMUSG00000001496, Nkx2-1, NK2 homeobox 1, [RH, Score=144, Expect=6e-39]} {Dmel: FBgn0028993, scro, scarecrow, [RH, Score=166, Expect=2e-46]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [RH, Score=136, Expect=1e-36]} {Smed: dd_Smed_v6_6729_0_1, dd_Smed_v6_6729_0_1, [RH, Score=193, Expect=1e-57]} {RNA1509_12761} {RNA1310_13401, RNA1509_12761} {RNA1509_12761, RNA815_21584}
6. MligTC455_25589 1419 29.55 Mlig455_029945

Neo: -

Age: -

Region-enriched R2: 2.293/0.00000

Regeneration-downregulated BL: -3.516

Regeneration-depleted BL: -3.516

4.453 0.738 0.987 0.742 - 0.994 0.992 Mlig455_029945 {REF} {Length: 1261} {Pfam: Helix-turn-helix domain [PF12645.9, score=19.8]; Domain of unknown function (DUF1848) [PF08902.13, score=19.3]} {RNA1509_17753} {RNA1310_70608, RNA1509_17753} {RNA1509_17753, RNA815_1498.1}
7. MligTC455_48609 3538 73.7 Mlig455_037431, Mlig455_037454, Mlig455_037501

Neo: -

Age: -

Region-specific R2: 3.134

Region-enriched R2: 1.985/0.00000

Regeneration-downregulated BL: -2.003

Regeneration-depleted BL: -2.003

CAPN5 4.451 0.819 0.839 0.907 - 0.950 0.936

Mlig455_037431 {REF} {Length: 2455} {Pfam: Calpain family cysteine protease [PF00648.23, score=124.0]} {Human: ENSG00000149260, CAPN5, calpain 5, [Score=106, Expect=2e-23]} {Mouse: ENSMUSG00000035547, Capn5, calpain 5, [Score=103, Expect=1e-22]} {Dmel: FBgn0012051, CalpA, Calpain-A, [Score=86.3, Expect=2e-17]} {Celegans: WBGene00006606, tra-3, Calpain-5, [Score=120, Expect=2e-28]} {Smed: dd_Smed_v6_8673_0_1, dd_Smed_v6_8673_0_1, [Score=103, Expect=5e-23]} {RNA1509_27234} {RNA1310_12131} {RNA815_7478.1}

Mlig455_037454 {REF} {Length: 1043} {RNA1509_15549} {RNA1310_57168} {RNA815_30048}

Mlig455_037501 {REF} {Length: 2687} {Pfam: Calpain family cysteine protease [PF00648.23, score=123.7]} {Human: ENSG00000149260, CAPN5, calpain 5, [Score=108, Expect=6e-24]} {Mouse: ENSMUSG00000035547, Capn5, calpain 5, [Score=105, Expect=5e-23]} {Dmel: FBgn0012051, CalpA, Calpain-A, [Score=86.3, Expect=2e-17]} {Celegans: WBGene00006606, tra-3, Calpain-5, [Score=120, Expect=3e-28]} {Smed: dd_Smed_v6_8673_0_1, dd_Smed_v6_8673_0_1, [Score=104, Expect=4e-23]} {RNA1509_27234} {RNA1310_12131} {RNA815_7478.1}
8. MligTC455_46667 769 16.02 Mlig455_007827

Neo: -

Age: -

Region-enriched R2: 2.396/0.00004

PLSCR3 4.299 0.820 0.771 0.937 0.789 0.982 - Mlig455_007827 {REF} {Length: 946} {Pfam: Scramblase [PF03803.17, score=174.8]} {Human: ENSG00000187838, PLSCR3, phospholipid scramblase 3, [Score=155, Expect=1e-46]; ENSG00000284009, PLSCR3, phospholipid scramblase 3, [Score=155, Expect=1e-46]; ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=153, Expect=2e-46]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=162, Expect=4e-49]; ENSMUSG00000019461, Plscr3, phospholipid scramblase 3, [Score=158, Expect=9e-48]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=151, Expect=7e-46]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=124, Expect=4e-35]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [Score=206, Expect=3e-66]} {RNA1509_32731, RNA1509_35060, RNA1509_60038} {RNA1310_24943, RNA1509_32731, RNA1509_35060, RNA1509_60038} {RNA1509_32731, RNA1509_35060, RNA1509_60038, RNA815_10647}
9. MligTC455_19660 1113 23.18 Mlig455_042835, Mlig455_045853, Mlig455_045869

Neo: -

Age: -

Region-enriched R2: 7.811/0.00000
Region-enriched R3: 5.032/0.00323
Region-enriched R5: 3.512/0.04347

CEP164 4.291 0.752 - 0.774 0.866 0.976 0.923

Mlig455_042835 {REF} {Length: 1693} {Pfam: WW domain [PF00397.28, score=23.4]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=69.3, Expect=5e-12]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=71.2, Expect=7e-13]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=73.6, Expect=5e-14]} {RNA1310_28636} {RNA815_10722}

Mlig455_045853 {REF} {Length: 1697} {Pfam: WW domain [PF00397.28, score=23.4]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=68.9, Expect=5e-12]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=71.2, Expect=7e-13]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=73.6, Expect=6e-14]} {RNA1310_28636} {RNA815_10722}

Mlig455_045869 {REF} {Length: 1704} {Pfam: WW domain [PF00397.28, score=23.4]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=68.9, Expect=5e-12]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=71.2, Expect=7e-13]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=73.6, Expect=6e-14]} {RNA1310_28636} {RNA815_10722}
10. MligTC455_33039 312 6.51 Mlig455_032494

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.545/0.00267

PKDREJ 4.285 0.713 0.914 0.788 - 0.970 0.900 Mlig455_032494 {REF} {Length: 11952} {Pfam: Polycystin cation channel [PF08016.14, score=289.9]; REJ domain [PF02010.17, score=90.4]; PLAT/LH2 domain [PF01477.25, score=68.4]; PKD domain [PF00801.22, score=57.9]; PKD domain [PF18911.2, score=36.7]; Ion transport protein [PF00520.33, score=36.3]; GPCR proteolysis site, GPS, motif [PF01825.23, score=30.0]; WSC domain [PF01822.21, score=23.3]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=267, Expect=1e-70]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=292, Expect=3e-78]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=136, Expect=2e-31]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [RH, Score=297, Expect=4e-80]} {Smed: dd_Smed_v6_15525_0_1, dd_Smed_v6_15525_0_1, [Score=1504, Expect=0.0]} {RNA1509_3444} {RNA1310_89} {RNA815_1814}
11. MligTC455_42994 1521 31.7 Mlig455_035840

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.356

Region-enriched R2: 1.854/0.00052

4.204 0.847 0.805 0.848 - 0.951 0.753 Mlig455_035840 {REF} {Length: 1436} {RNA1509_29485, RNA1509_42231} {RNA1310_26640, RNA1509_29485, RNA1509_42231} {RNA1509_29485, RNA1509_42231, RNA815_37260}
12. MligTC455_19276 1694 35.28 Mlig455_057303

Neo: -

Age: Down-Down-Up

Region-specific R2: 5.711

Region-enriched R2: 6.117/0.00000
Region-enriched R3: 2.663/0.00058

4.203 0.830 0.755 0.880 - 0.960 0.778 Mlig455_057303 {REF} {Length: 1196} {Pfam: TATA-binding related factor (TRF) of subunit 20 of Mediator complex [PF08612.13, score=80.6]} {Smed: dd_Smed_v6_9879_0_1, dd_Smed_v6_9879_0_1, [RH, Score=73.9, Expect=1e-15]} {RNA1509_58478} {RNA1310_35292} {RNA815_20171}
13. MligTC455_19278 4335 90.31 Mlig455_057304, Mlig455_070944

Neo: -

Age: logFC(26M/2M)=0.686

Region-specific R2: 5.590

Region-enriched R2: 5.465/0.00000
Region-enriched R3: 2.308/0.00629

CHRNA10 4.18 0.854 0.767 0.823 - 0.958 0.778

Mlig455_057304 {REF} {Length: 1001} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=71.6]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=77.0, Expect=2e-16]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=75.9, Expect=4e-16]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=75.5, Expect=6e-16]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=73.9, Expect=2e-15]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=93.6, Expect=2e-22]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=100, Expect=5e-25]} {Smed: dd_Smed_v6_11955_0_1, dd_Smed_v6_11955_0_1, [Score=82.8, Expect=8e-19]} {RNA1509_23115} {RNA1310_34970} {RNA815_15305.1}

Mlig455_070944 {REF} {Length: 1060} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=88.2]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=95.9, Expect=6e-22]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=96.3, Expect=3e-22]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=94.7, Expect=1e-21]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=112, Expect=7e-28]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=118, Expect=4e-30]} {Smed: dd_Smed_v6_18184_0_1, dd_Smed_v6_18184_0_1, [Score=98.6, Expect=2e-23]} {RNA1509_23115, RNA1509_43907, RNA1509_9432} {RNA1310_34970, RNA1509_23115, RNA1509_43907, RNA1509_9432} {RNA1509_23115, RNA1509_43907, RNA1509_9432, RNA815_15305.1}
14. MligTC455_47716 1445 30.1 Mlig455_062374, Mlig455_062397

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.444

Region-enriched R2: 3.549/0.00000
Region-enriched R4: 2.056/0.01731

4.127 0.749 0.788 0.772 - 0.855 0.963

Mlig455_062374 {REF} {Length: 899} {RNA1509_16194} {RNA1310_50819.1} {RNA815_25538}

Mlig455_062397 {REF} {Length: 907} {RNA1509_16194} {RNA1310_50819.1, RNA1509_16194} {RNA1509_16194, RNA815_25538}
15. MligTC455_48616 1121 23.36 Mlig455_045633

Neo: -

Age: -

CCDC81 4.125 0.805 - 0.848 0.960 0.739 0.773 Mlig455_045633 {REF} {Length: 4045} {Pfam: CCDC81 eukaryotic HU domain 2 [PF18289.3, score=77.2]; CCDC81 eukaryotic HU domain 1 [PF14908.8, score=72.1]; Bacterial DNA-binding protein [PF00216.23, score=21.4]; HU domain fused to wHTH, Ig, or Glycine-rich motif [PF18291.3, score=18.8]} {Human: ENSG00000149201, CCDC81, coiled-coil domain containing 81, [RH, Score=242, Expect=6e-70]} {Mouse: ENSMUSG00000039391, Ccdc81, coiled-coil domain containing 81, [RH, Score=217, Expect=5e-61]} {Smed: dd_Smed_v6_6753_0_1, dd_Smed_v6_6753_0_1, [RH, Score=586, Expect=0.0]} {RNA1509_2273} {RNA1310_2378} {RNA815_610}
16. MligTC455_35258 2779 57.89 Mlig455_040964

Neo: -

Age: Up-Down-Down

Region-specific R2: 2.469

Region-enriched R2: 1.501/0.00133

4.085 0.823 0.705 0.803 - 0.970 0.784 Mlig455_040964 {REF} {Length: 8259} {Smed: dd_Smed_v6_8425_0_1, dd_Smed_v6_8425_0_1, [Score=543, Expect=9e-160]} {RNA1509_16633, RNA1509_52679} {RNA1310_236.2, RNA1509_16633} {RNA1509_16633, RNA815_77.1}
17. MligTC455_45977 2671 55.65 Mlig455_023593, Mlig455_068112

Neo: -

Age: logFC(26M/2M)=-0.892

Region-enriched R2: 2.870/0.00031

MUC4 3.98 0.749 0.820 0.747 - 0.709 0.955

Mlig455_023593 {REF} {Length: 6716} {TRANSSPLICED} {Pfam: Calcium-binding EGF domain [PF07645.17, score=81.4]; EGF-like domain [PF00008.29, score=74.6]; EGF domain [PF12947.9, score=64.6]; Complement Clr-like EGF-like [PF12662.9, score=58.7]; von Willebrand factor type D domain [PF00094.27, score=54.6]; Coagulation Factor Xa inhibitory site [PF14670.8, score=40.9]; Human growth factor-like EGF [PF12661.9, score=38.7]; Nidogen-like [PF06119.16, score=25.5]} {Human: ENSG00000278303, MUC4, mucin 4, cell surface associated, [RH, Score=137, Expect=2e-31]; ENSG00000145113, MUC4, mucin 4, cell surface associated, [RH, Score=137, Expect=2e-31]; ENSG00000277585, MUC4, mucin 4, cell surface associated, [RH, Score=137, Expect=2e-31]; ENSG00000273822, MUC4, mucin 4, cell surface associated, [RH, Score=137, Expect=2e-31]; ENSG00000273984, MUC4, mucin 4, cell surface associated, [RH, Score=137, Expect=2e-31]; ENSG00000276613, MUC4, mucin 4, cell surface associated, [RH, Score=137, Expect=2e-31]; ENSG00000278468, MUC4, mucin 4, cell surface associated, [RH, Score=135, Expect=6e-31]} {Mouse: ENSMUSG00000079620, Muc4, mucin 4, [RH, Score=112, Expect=6e-24]} {Dmel: FBgn0004647, N, Notch, [Score=103, Expect=2e-21]} {Celegans: WBGene00000792, crb-1, Drosophila CRumBs homolog, [Score=94.0, Expect=1e-18]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [Score=92.0, Expect=3e-18]} {RNA1509_5446} {RNA1310_1366} {RNA815_327.2}

Mlig455_068112 {REF} {Length: 6638} {TRANSSPLICED} {Pfam: Calcium-binding EGF domain [PF07645.17, score=82.1]; EGF-like domain [PF00008.29, score=75.3]; EGF domain [PF12947.9, score=65.2]; Complement Clr-like EGF-like [PF12662.9, score=59.4]; von Willebrand factor type D domain [PF00094.27, score=54.7]; Coagulation Factor Xa inhibitory site [PF14670.8, score=41.6]; Human growth factor-like EGF [PF12661.9, score=39.4]; Nidogen-like [PF06119.16, score=25.6]} {Human: ENSG00000273822, MUC4, mucin 4, cell surface associated, [RH, Score=135, Expect=1e-30]; ENSG00000277585, MUC4, mucin 4, cell surface associated, [RH, Score=135, Expect=1e-30]; ENSG00000276613, MUC4, mucin 4, cell surface associated, [RH, Score=135, Expect=1e-30]; ENSG00000273984, MUC4, mucin 4, cell surface associated, [RH, Score=135, Expect=1e-30]; ENSG00000278303, MUC4, mucin 4, cell surface associated, [RH, Score=135, Expect=1e-30]; ENSG00000145113, MUC4, mucin 4, cell surface associated, [RH, Score=135, Expect=7e-31]; ENSG00000278468, MUC4, mucin 4, cell surface associated, [RH, Score=133, Expect=3e-30]} {Mouse: ENSMUSG00000079620, Muc4, mucin 4, [RH, Score=110, Expect=2e-23]} {Dmel: FBgn0004647, N, Notch, [Score=103, Expect=2e-21]} {Celegans: WBGene00000792, crb-1, Drosophila CRumBs homolog, [Score=93.6, Expect=1e-18]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [Score=92.4, Expect=3e-18]} {RNA1509_20713, RNA1509_53794, RNA1509_5446} {RNA1310_1366, RNA1509_20713, RNA1509_53794} {RNA1509_20713, RNA1509_53794, RNA815_327.2}
18. MligTC455_38682 102 2.12 Mlig455_039641

Neo: -

Age: -

Region-enriched R2: 6.138/0.02363

SLC18A3 3.961 0.719 0.702 0.820 - 0.964 0.756 Mlig455_039641 {REF} {Length: 3925} {Pfam: Major Facilitator Superfamily [PF07690.18, score=147.1]; Sugar (and other) transporter [PF00083.26, score=29.0]; LacY proton/sugar symporter [PF01306.21, score=20.2]} {Human: ENSG00000187714, SLC18A3, solute carrier family 18 member A3, [RH, Score=469, Expect=9e-161]} {Mouse: ENSMUSG00000100241, Slc18a3, solute carrier family 18 (vesicular monoamine), member 3, [RH, Score=469, Expect=1e-160]} {Dmel: FBgn0270928, VAChT, Vesicular acetylcholine transporter, [RH, Score=513, Expect=2e-177]} {Celegans: WBGene00006756, unc-17, Vesicular acetylcholine transporter unc-17, [RH, Score=486, Expect=2e-167]} {Smed: dd_Smed_v6_11630_0_1, dd_Smed_v6_11630_0_1, [RH, Score=563, Expect=0.0]} {RNA1310_28397} {RNA815_32284.1}
19. MligTC455_17701 1279 26.65 Mlig455_051483

Neo: -

Age: Down-Up-Up

Region-specific R2: 5.592

Region-enriched R2: 6.602/0.00000
Region-enriched R3: 2.598/0.04295

3.662 0.805 - 0.898 - 0.976 0.983 Mlig455_051483 {REF} {Length: 1833} {RNA1509_14131} {RNA1310_69964.2, RNA1509_14131} {RNA1509_14131, RNA815_35453.1}
20. MligTC455_18599 119 2.47 Mlig455_031197

Neo: -

Age: Down-Up-Up

Region-enriched R2: 4.553/0.00808

3.66 - 0.923 0.887 - 0.871 0.979 Mlig455_031197 {REF} {Length: 1284} {RNA1310_35452}
21. MligTC455_51199 206 4.29 Mlig455_044015

Neo: -

Age: Down-Up-Down

ARX 3.653 - 0.919 0.821 - 0.956 0.957 Mlig455_044015 {REF} {Length: 1926} {Pfam: Homeodomain [PF00046.31, score=85.3]} {Human: ENSG00000004848, ARX, aristaless related homeobox, [Score=116, Expect=8e-30]} {Mouse: ENSMUSG00000035277, Arx, aristaless related homeobox, [Score=115, Expect=1e-29]} {Dmel: FBgn0008636, hbn, homeobrain, [Score=128, Expect=5e-35]} {Celegans: WBGene00000433, ceh-8, Homeobox protein ceh-8, [RH, Score=103, Expect=6e-27]} {Smed: dd_Smed_v6_16955_0_1, dd_Smed_v6_16955_0_1, [Score=105, Expect=9e-27]} {RNA1509_46102} {RNA1310_37906, RNA1509_46102}
22. MligTC455_51710 3251 67.72 Mlig455_024427

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.451

Region-enriched R8: 1.126/0.01211

3.612 0.735 0.914 - - 0.980 0.983 Mlig455_024427 {REF} {Length: 2323} {RNA1509_28514} {RNA1310_24129} {RNA815_10418.2}
23. MligTC455_51712 12157 253.26 Mlig455_024579

Neo: -

Age: logFC(26M/2M)=-0.392

Region-enriched R8: 1.189/0.00026

Regeneration-downregulated TP: -1.372

Regeneration-depleted TP: -1.372

3.605 0.737 0.964 - - 0.924 0.980 Mlig455_024579 {REF} {Length: 1524} {RNA1509_28514, RNA1509_35723} {RNA1310_24129, RNA1509_35723} {RNA1509_35723, RNA815_10418.2}
24. MligTC455_39467 6156 128.24 Mlig455_066728, Mlig455_066742

Neo: -

Age: logFC(26M/2M)=-0.137

Region-specific R2: 2.002

Region-enriched R2: 1.402/0.00004

PC 3.587 - 0.794 0.845 - 0.994 0.954

Mlig455_066728 {REF} {Length: 4310} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=220.4]; Conserved carboxylase domain [PF02436.20, score=216.0]; Biotin carboxylase, N-terminal domain [PF00289.24, score=144.7]; Biotin carboxylase C-terminal domain [PF02785.21, score=102.8]; HMGL-like [PF00682.21, score=93.0]; Biotin-requiring enzyme [PF00364.24, score=57.9]; Biotin-lipoyl like [PF13533.8, score=28.3]; D-ala D-ala ligase C-terminus [PF07478.15, score=25.5]; ATP-grasp domain [PF02222.24, score=24.6]} {Human: ENSG00000173599, PC, pyruvate carboxylase, [Score=1375, Expect=0.0]} {Mouse: ENSMUSG00000024892, Pcx, pyruvate carboxylase, [Score=1365, Expect=0.0]} {Dmel: FBgn0027580, PCB, Pyruvate carboxylase, [Score=1419, Expect=0.0]} {Celegans: WBGene00004258, pyc-1, Pyruvate carboxylase 1, [Score=1371, Expect=0.0]} {Smed: dd_Smed_v6_2393_0_1, dd_Smed_v6_2393_0_1, [Score=1440, Expect=0.0]} {RNA1509_292} {RNA1310_1178} {RNA815_516.1}

Mlig455_066742 {REF} {Length: 4334} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=265.4]; Biotin carboxylase, N-terminal domain [PF00289.24, score=117.2]; Biotin carboxylase C-terminal domain [PF02785.21, score=104.0]; ATP-grasp domain [PF02222.24, score=37.0]; D-ala D-ala ligase C-terminus [PF07478.15, score=34.3]; ATP-grasp domain [PF02655.16, score=18.8]; HMGL-like [PF00682.21, score=18.3]} {Human: ENSG00000173599, PC, pyruvate carboxylase, [Score=837, Expect=0.0]} {Mouse: ENSMUSG00000024892, Pcx, pyruvate carboxylase, [Score=826, Expect=0.0]} {Dmel: FBgn0027580, PCB, Pyruvate carboxylase, [Score=839, Expect=0.0]} {Celegans: WBGene00004258, pyc-1, Pyruvate carboxylase 1, [Score=808, Expect=0.0]} {Smed: dd_Smed_v6_2393_0_1, dd_Smed_v6_2393_0_1, [Score=851, Expect=0.0]} {RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579} {RNA1310_1642, RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579} {RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579, RNA815_516.1}
25. MligTC455_51711 12053 251.1 Mlig455_024544

Neo: -

Age: logFC(26M/2M)=0.250

Region-specific R2: 1.689

Region-enriched R8: 1.181/0.00003

Regeneration-downregulated TP: -1.390

Regeneration-depleted TP: -1.390

3.583 0.729 0.960 - - 0.913 0.981 Mlig455_024544 {REF} {Length: 1633} {RNA1509_891} {RNA1310_24129} {RNA815_10418.2}
26. MligTC455_20441 7966 165.95 Mlig455_066269

Neo: -

Age: logFC(26M/2M)=-0.347

Regeneration-downregulated BL: -1.038

Regeneration-depleted BL: -1.038

TSPAN16 3.576 - 0.886 0.830 - 0.904 0.956 Mlig455_066269 {REF} {Length: 2526} {Pfam: Tetraspanin family [PF00335.22, score=77.2]} {Human: ENSG00000130167, TSPAN16, tetraspanin 16, [Score=49.3, Expect=2e-06]} {Mouse: ENSMUSG00000067377, Tspan6, tetraspanin 6, [Score=48.1, Expect=4e-06]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [Score=66.6, Expect=2e-12]} {Smed: dd_Smed_v6_3175_0_1, dd_Smed_v6_3175_0_1, [RH, Score=105, Expect=2e-26]} {RNA1509_1984} {RNA1310_20011, RNA1509_1984} {RNA1509_1984, RNA815_7057.1}
27. MligTC455_20442 14887 310.15 Mlig455_023972, Mlig455_066251

Neo: -

Age: Down-Up-Up

TSPAN16 3.568 - 0.888 0.852 - 0.878 0.950

Mlig455_023972 {REF} {Length: 2924} {Pfam: Tetraspanin family [PF00335.22, score=77.6]} {Human: ENSG00000130167, TSPAN16, tetraspanin 16, [Score=49.3, Expect=2e-06]} {Mouse: ENSMUSG00000067377, Tspan6, tetraspanin 6, [Score=48.1, Expect=4e-06]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [Score=67.0, Expect=1e-12]} {Smed: dd_Smed_v6_3175_0_1, dd_Smed_v6_3175_0_1, [RH, Score=105, Expect=2e-26]} {RNA1509_1984} {RNA1310_20011} {RNA815_7057.1}

Mlig455_066251 {REF} {Length: 2553} {Pfam: Tetraspanin family [PF00335.22, score=77.6]} {Human: ENSG00000130167, TSPAN16, tetraspanin 16, [Score=49.3, Expect=2e-06]} {Mouse: ENSMUSG00000067377, Tspan6, tetraspanin 6, [Score=48.1, Expect=4e-06]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [Score=67.0, Expect=1e-12]} {Smed: dd_Smed_v6_3175_0_1, dd_Smed_v6_3175_0_1, [RH, Score=105, Expect=2e-26]} {RNA1509_18769, RNA1509_1984, RNA1509_20386} {RNA1310_20011, RNA1509_18769, RNA1509_20386} {RNA1509_18769, RNA1509_20386, RNA815_7057.1}
28. MligTC455_20440 7716 160.76 Mlig455_034502

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.410

TSPAN16 3.564 - 0.884 0.850 - 0.868 0.962 Mlig455_034502 {REF} {Length: 1176} {Pfam: Tetraspanin family [PF00335.22, score=77.6]} {Human: ENSG00000130167, TSPAN16, tetraspanin 16, [Score=49.3, Expect=2e-06]} {Mouse: ENSMUSG00000067377, Tspan6, tetraspanin 6, [Score=48.1, Expect=4e-06]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [Score=67.0, Expect=1e-12]} {Smed: dd_Smed_v6_3175_0_1, dd_Smed_v6_3175_0_1, [RH, Score=105, Expect=2e-26]} {RNA1509_1984, RNA1509_52808} {RNA1310_20011, RNA1509_52808} {RNA1509_52808, RNA815_7057.1}
29. MligTC455_41199 7523 156.73 Mlig455_001888, Mlig455_048783

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.793

CFAP45 3.563 - - 0.837 0.969 0.885 0.872

Mlig455_001888 {REF} {Length: 2583} {Pfam: Trichohyalin-plectin-homology domain [PF13868.8, score=192.2]} {Human: ENSG00000213085, CFAP45, cilia and flagella associated protein 45, [Score=301, Expect=2e-95]} {Mouse: ENSMUSG00000026546, Cfap45, cilia and flagella associated protein 45, [Score=296, Expect=2e-93]} {Dmel: FBgn0037162, CG11449, [Score=100, Expect=4e-22]} {Smed: dd_Smed_v6_3732_0_1, dd_Smed_v6_3732_0_1, [Score=407, Expect=1e-136]} {RNA1509_2741} {RNA1310_7881.1} {RNA815_2376.1}

Mlig455_048783 {REF} {Length: 2929} {Pfam: Trichohyalin-plectin-homology domain [PF13868.8, score=268.3]} {Human: ENSG00000213085, CFAP45, cilia and flagella associated protein 45, [RH, Score=371, Expect=6e-122]} {Mouse: ENSMUSG00000026546, Cfap45, cilia and flagella associated protein 45, [RH, Score=365, Expect=9e-120]} {Dmel: FBgn0037162, CG11449, [RH, Score=116, Expect=2e-27]} {Smed: dd_Smed_v6_3732_0_1, dd_Smed_v6_3732_0_1, [RH, Score=478, Expect=5e-164]} {RNA1509_11068, RNA1509_22358, RNA1509_2741, RNA1509_455} {RNA1310_7881.1, RNA1509_11068, RNA1509_22358, RNA1509_2741} {RNA1509_11068, RNA1509_22358, RNA1509_2741, RNA815_2376.1}
30. MligTC455_40444 2996 62.42 Mlig455_039527, Mlig455_051318

Neo: -

Age: Down-Up-Down

3.517 0.816 - 0.785 - 0.932 0.984

Mlig455_039527 {REF} {Length: 710} {RNA1509_7655} {RNA1310_63393} {RNA815_30324}

Mlig455_051318 {REF} {Length: 721} {RNA1509_7655} {RNA1310_63393, RNA1509_7655} {RNA1509_7655, RNA815_30324}
31. MligTC455_41368 369 7.68 Mlig455_007683, Mlig455_020872, Mlig455_020918, Mlig455_020998

Neo: -

Age: -

3.506 0.764 - 0.847 - 0.916 0.979

Mlig455_007683 {REF} {Length: 1379} {RNA1310_25040.2} {RNA815_12562.1}

Mlig455_020872 {REF} {Length: 1217} {RNA1310_25040.2} {RNA815_12562.1}

Mlig455_020918 {REF} {Length: 1220} {RNA1310_25040.2} {RNA815_12562.1}

Mlig455_020998 {REF} {Length: 1235} {RNA1310_25040.1} {RNA815_12562.1}
32. MligTC455_20144 1943 40.48 Mlig455_007028, Mlig455_007029, Mlig455_069137

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.663

Region-enriched R2: 1.755/0.00284

Regeneration-downregulated BL: -2.689

Regeneration-depleted BL: -2.689

3.501 - 0.942 0.791 - 0.784 0.984

Mlig455_007028 {REF} {Length: 1192} {NoTransDecoderORF} {RNA1509_19530, RNA1509_24021} {RNA1310_20554, RNA1509_19530, RNA1509_24021} {RNA1509_19530, RNA1509_24021, RNA815_8810.1}

Mlig455_007029 {REF} {Length: 915} {RNA1509_30060} {RNA1310_40388.1} {RNA815_20453}

Mlig455_069137 {REF} {Length: 3938} {RNA1509_4350} {RNA1310_20554} {RNA815_8810.1}
33. MligTC455_42037 1931 40.23 Mlig455_063391

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.444

Region-specific R2: 2.479

Region-enriched R2: 1.442/0.00136

3.487 - 0.880 0.790 - 0.980 0.837 Mlig455_063391 {REF} {Length: 1482} {RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236} {RNA1310_24553, RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236} {RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236, RNA815_11766}
34. MligTC455_31853 516 10.74 Mlig455_014495, Mlig455_014514, Mlig455_054434

Neo: -

Age: -

3.473 0.758 - 0.910 - 0.952 0.853

Mlig455_014495 {REF} {Length: 3100} {RNA1509_20117} {RNA1310_5956.1, RNA1509_20117} {RNA1509_20117, RNA815_18508}

Mlig455_014514 {REF} {Length: 3051} {Smed: dd_Smed_v6_3795_0_2, dd_Smed_v6_3795_0_2, [RH, Score=89.7, Expect=2e-19]} {RNA1509_20117} {RNA1310_5956.1} {RNA815_18508}

Mlig455_054434 {REF} {Length: 4026} {Pfam: Late embryogenesis abundant protein [PF03242.15, score=21.0]} {Smed: dd_Smed_v6_3795_0_2, dd_Smed_v6_3795_0_2, [RH, Score=89.4, Expect=2e-20]} {RNA1509_20117} {RNA1310_8165} {RNA815_23492}
35. MligTC455_41328 417 8.68 Mlig455_057091

Neo: -

Age: Down-Up-Down

Region-enriched R2: 6.162/0.00002

3.453 0.709 - - 0.926 0.955 0.863 Mlig455_057091 {REF} {Length: 854} {RNA1310_89414} {RNA815_40489.2}
36. MligTC455_43001 2139 44.57 Mlig455_004256, Mlig455_004325

Neo: -

Age: -

Region-enriched R2: 2.362/0.00019

GLUD1 3.444 - 0.763 0.855 0.984 0.842 -

Mlig455_004256 {REF} {Length: 1969} {Pfam: Glu/Leu/Phe/Val dehydrogenase, dimerisation domain [PF02812.20, score=185.6]; Glutamate/Leucine/Phenylalanine/Valine dehydrogenase [PF00208.23, score=175.9]} {Human: ENSG00000148672, GLUD1, glutamate dehydrogenase 1, [Score=639, Expect=0.0]; ENSG00000182890, GLUD2, glutamate dehydrogenase 2, [Score=639, Expect=0.0]} {Mouse: ENSMUSG00000021794, Glud1, glutamate dehydrogenase 1, [Score=639, Expect=0.0]} {Dmel: FBgn0001098, Gdh, Glutamate dehydrogenase, [Score=613, Expect=0.0]} {Celegans: WBGene00014095, gdh-1, Glutamate dehydrogenase, [Score=558, Expect=0.0]} {Smed: dd_Smed_v6_932_0_1, dd_Smed_v6_932_0_1, [Score=641, Expect=0.0]} {RNA1509_30743} {RNA1310_2661.2} {RNA815_713.2}

Mlig455_004325 {REF} {Length: 2236} {Pfam: Glu/Leu/Phe/Val dehydrogenase, dimerisation domain [PF02812.20, score=185.5]; Glutamate/Leucine/Phenylalanine/Valine dehydrogenase [PF00208.23, score=174.7]} {Human: ENSG00000148672, GLUD1, glutamate dehydrogenase 1, [Score=642, Expect=0.0]; ENSG00000182890, GLUD2, glutamate dehydrogenase 2, [Score=640, Expect=0.0]} {Mouse: ENSMUSG00000021794, Glud1, glutamate dehydrogenase 1, [Score=641, Expect=0.0]} {Dmel: FBgn0001098, Gdh, Glutamate dehydrogenase, [Score=613, Expect=0.0]} {Celegans: WBGene00014095, gdh-1, Glutamate dehydrogenase, [Score=558, Expect=0.0]} {Smed: dd_Smed_v6_932_0_1, dd_Smed_v6_932_0_1, [Score=639, Expect=0.0]} {RNA1509_10773, RNA1509_30743} {RNA1310_2661.2, RNA1509_10773, RNA1509_30743} {RNA1509_10773, RNA1509_30743, RNA815_713.2}
37. MligTC455_53579 15576 324.49 Mlig455_010515

Neo: -

Age: -

Region-enriched R2: 1.446/0.00265

Regeneration-downregulated BL: -1.566

Regeneration-depleted BL: -1.566

3.441 0.797 0.752 - - 0.955 0.937 Mlig455_010515 {REF} {Length: 1448} {Pfam: Neuroendocrine protein 7B2 precursor (Secretogranin V) [PF05281.13, score=80.3]} {Dmel: FBgn0041707, 7B2, [RH, Score=70.1, Expect=2e-13]} {Celegans: WBGene00011392, sbt-1, Seven B Two (Mammalian 7BT prohormone convertase chaperone) homolog, [RH, Score=67.4, Expect=5e-13]} {Smed: dd_Smed_v6_3862_0_1, dd_Smed_v6_3862_0_1, [RH, Score=119, Expect=7e-32]} {RNA1509_1202, RNA1509_1348, RNA1509_17830} {RNA1310_24594, RNA1509_1202, RNA1509_1348, RNA1509_17830} {RNA1509_1202, RNA1509_1348, RNA1509_17830, RNA815_8289}
38. MligTC455_47094 240 5.01 Mlig455_014204

Neo: -

Age: logFC(26M/2M)=-0.357

3.435 - 0.812 0.897 - 0.769 0.957 Mlig455_014204 {REF} {Length: 3346} {Smed: dd_Smed_v6_4351_0_1, dd_Smed_v6_4351_0_1, [RH, Score=238, Expect=1e-74]} {RNA1509_35661} {RNA1310_8437, RNA1509_35661} {RNA1509_35661, RNA815_15552}
39. MligTC455_42963 247 5.15 Mlig455_002825

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.597

Region-enriched R2: 5.687/0.00012

3.434 - - 0.802 0.888 0.953 0.791 Mlig455_002825 {REF} {Length: 726} {RNA1310_78982} {RNA815_41084}
40. MligTC455_34115 6573 136.93 Mlig455_017846, Mlig455_047865

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.581

Region-enriched R2: 4.896/0.00130

3.416 0.702 - 0.827 - 0.960 0.927

Mlig455_017846 {REF} {Length: 1260} {RNA1509_3560, RNA1509_36840, RNA1509_42552, RNA1509_4845, RNA1509_7701} {RNA1310_63880, RNA1509_3560, RNA1509_36840, RNA1509_42552, RNA1509_4845, RNA1509_7701} {RNA1509_3560, RNA1509_36840, RNA1509_42552, RNA1509_4845, RNA1509_7701, RNA815_12890.1}

Mlig455_047865 {REF} {Length: 1135} {RNA1509_4845} {RNA1310_63880} {RNA815_12890.1}
41. MligTC455_17351 766 15.96 Mlig455_009441

Neo: -

Age: -

Region-enriched R2: 2.466/0.00083
Region-enriched R4: 1.757/0.02374

USH2A 3.412 - - 0.787 0.953 0.933 0.739 Mlig455_009441 {REF} {Length: 3984} {Pfam: Fibronectin type III domain [PF00041.23, score=76.6]; Neuron-derived neurotrophic factor [PF10179.11, score=24.4]; Fibronectin type III domain [PF16893.7, score=23.7]; Purple acid Phosphatase, N-terminal domain [PF16656.7, score=22.6]; HEAT repeats [PF13646.8, score=22.2]} {Human: ENSG00000042781, USH2A, usherin, [Score=94.7, Expect=7e-19]} {Mouse: ENSMUSG00000026609, Ush2a, usherin, [Score=77.0, Expect=1e-13]} {Dmel: FBgn0259735, CG42389, [Score=59.3, Expect=2e-08]} {Celegans: WBGene00010558, ptp-4, Tyrosine-protein phosphatase 4, [Score=51.2, Expect=4e-06]} {Smed: dd_Smed_v6_15017_0_1, dd_Smed_v6_15017_0_1, [RH, Score=411, Expect=8e-129]} {RNA1509_13146, RNA1509_35474, RNA1509_50831} {RNA1310_2905.1, RNA1509_13146, RNA1509_35474, RNA1509_50831} {RNA1509_13146, RNA1509_35474, RNA1509_50831, RNA815_2595.1}
42. MligTC455_30801 483 10.05 Mlig455_027631, Mlig455_027642

Neo: -

Age: Up-Down-Down

Region-enriched R4: 2.277/0.03108

TRPM7 3.408 - 0.740 0.865 0.955 0.848 -

Mlig455_027631 {REF} {Length: 3904} {Pfam: Ion transport protein [PF00520.33, score=35.0]} {Human: ENSG00000092439, TRPM7, transient receptor potential cation channel subfamily M member 7, [Score=79.0, Expect=3e-14]} {Mouse: ENSMUSG00000027365, Trpm7, transient receptor potential cation channel, subfamily M, member 7, [Score=73.9, Expect=5e-13]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=81.6, Expect=2e-15]} {Celegans: WBGene00001651, gon-2, Transient receptor potential channel, [Score=70.5, Expect=3e-12]} {Smed: dd_Smed_v6_26251_0_1, dd_Smed_v6_26251_0_1, [Score=100, Expect=1e-21]} {RNA1509_8759} {RNA1310_4330.3, RNA1509_8759} {RNA1509_8759, RNA815_1383.1}

Mlig455_027642 {REF} {Length: 4185} {Pfam: Ion transport protein [PF00520.33, score=35.0]} {Human: ENSG00000092439, TRPM7, transient receptor potential cation channel subfamily M member 7, [Score=76.3, Expect=1e-13]} {Mouse: ENSMUSG00000027365, Trpm7, transient receptor potential cation channel, subfamily M, member 7, [Score=71.6, Expect=3e-12]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=81.3, Expect=2e-15]} {Celegans: WBGene00001651, gon-2, Transient receptor potential channel, [Score=70.5, Expect=3e-12]} {Smed: dd_Smed_v6_26251_0_1, dd_Smed_v6_26251_0_1, [Score=100, Expect=1e-21]} {RNA1509_8759} {RNA1310_3171.2} {RNA815_1383.1}
43. MligTC455_47807 2664 55.5 Mlig455_050143

Neo: -

Age: -

Region-specific R2: 3.807

Region-enriched R2: 2.561/0.00001

3.399 0.719 - 0.767 - 0.928 0.985 Mlig455_050143 {REF} {Length: 1560} {RNA1509_1605, RNA1509_28756} {RNA1310_30659.1, RNA1509_28756} {RNA1509_28756, RNA815_13807}
44. MligTC455_17383 1327 27.64 Mlig455_022114, Mlig455_053650

Neo: -

Age: -

3.379 - - 0.843 0.955 0.860 0.721

Mlig455_022114 {REF} {Length: 3990} {Pfam: Domain of Unknown Function (DUF1542) [PF07564.13, score=21.5]} {RNA1509_4411} {RNA1310_4537.1, RNA1509_4411} {RNA1509_4411, RNA815_1371}

Mlig455_053650 {REF} {Length: 4005} {Pfam: Domain of Unknown Function (DUF1542) [PF07564.13, score=21.5]} {RNA1509_4411, RNA1509_52435} {RNA1310_4537.1, RNA1509_52435} {RNA1509_52435, RNA815_1371}
45. MligTC455_52437 3231 67.32 Mlig455_030528

Neo: -

Age: logFC(26M/2M)=-0.247

CCDC151 3.379 0.795 - - 0.962 0.831 0.791 Mlig455_030528 {REF} {Length: 2413} {TRANSSPLICED} {Human: ENSG00000198003, CCDC151, coiled-coil domain containing 151, [RH, Score=282, Expect=2e-87]} {Mouse: ENSMUSG00000039632, Ccdc151, coiled-coil domain containing 151, [RH, Score=290, Expect=1e-90]} {Dmel: FBgn0036219, CCDC151, Coiled-coil domain containing protein 151, [RH, Score=101, Expect=2e-22]} {Smed: dd_Smed_v6_4526_0_1, dd_Smed_v6_4526_0_1, [RH, Score=541, Expect=0.0]} {RNA1509_18674, RNA1509_25371, RNA1509_28757, RNA1509_589, RNA1509_7635, RNA1509_8351} {RNA1310_18029, RNA1509_18674, RNA1509_25371, RNA1509_28757, RNA1509_589, RNA1509_7635, RNA1509_8351} {RNA1509_18674, RNA1509_25371, RNA1509_28757, RNA1509_589, RNA1509_7635, RNA1509_8351, RNA815_6510}
46. MligTC455_15330 373 7.77 Mlig455_020220

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.289

3.375 0.770 0.874 - - 0.958 0.773 Mlig455_020220 {REF} {Length: 2115} {Pfam: Fas apoptotic inhibitory molecule (FAIM1) [PF06905.15, score=41.4]} {Smed: dd_Smed_v6_4798_0_1, dd_Smed_v6_4798_0_1, [RH, Score=82.0, Expect=3e-20]} {RNA1509_28885, RNA1509_54654} {RNA1310_42962.2, RNA1509_28885, RNA1509_54654} {RNA1509_28885, RNA1509_54654, RNA815_23071}
47. MligTC455_39957 170 3.54 Mlig455_039809

Neo: -

Age: -

Region-specific R2: 4.733

Region-enriched R2: 5.232/0.00000

ADGB 3.368 0.810 - 0.866 - 0.963 0.729 Mlig455_039809 {REF} {Length: 7010} {tRNA: Ile(TAT),pseudo, score=33.4} {Pfam: Calpain family cysteine protease [PF00648.23, score=34.1]} {Human: ENSG00000118492, ADGB, androglobin, [Score=403, Expect=6e-115]} {Mouse: ENSMUSG00000050994, Adgb, androglobin, [Score=252, Expect=4e-67]} {Celegans: WBGene00000543, clp-2, CaLPain family, [Score=73.2, Expect=1e-12]} {Smed: dd_Smed_v6_10677_0_1, dd_Smed_v6_10677_0_1, [Score=253, Expect=8e-68]} {RNA1509_15950, RNA1509_59203} {RNA1310_4821, RNA1509_59203} {RNA1509_59203, RNA815_12506}
48. MligTC455_49307 122 2.55 Mlig455_055230

Neo: -

Age: -

Region-enriched R2: 4.447/0.04819

ZAN 3.359 0.740 - 0.903 - 0.990 0.726 Mlig455_055230 {REF} {Length: 2947} {Pfam: Glycine rich protein [PF12810.9, score=28.6]} {Human: ENSG00000146839, ZAN, zonadhesin (gene/pseudogene), [Score=79.7, Expect=1e-14]} {Mouse: ENSMUSG00000079173, Zan, zonadhesin, [Score=80.1, Expect=7e-15]} {RNA1310_18897} {RNA815_40026}
49. MligTC455_19030 628 13.08 Mlig455_046052

Neo: -

Age: -

Region-enriched R2: 3.353/0.00000

ADGRL3 3.352 0.793 - - 0.821 0.971 0.767 Mlig455_046052 {REF} {Length: 7405} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=104.9]; 7 transmembrane receptor (Secretin family) [PF00002.26, score=61.8]; GPCR proteolysis site, GPS, motif [PF01825.23, score=54.3]; GPCR-Autoproteolysis INducing (GAIN) domain [PF16489.7, score=28.0]} {Human: ENSG00000150471, ADGRL3, adhesion G protein-coupled receptor L3, [Score=157, Expect=8e-38]} {Mouse: ENSMUSG00000037605, Adgrl3, adhesion G protein-coupled receptor L3, [Score=158, Expect=5e-38]} {Dmel: FBgn0033313, Cirl, Calcium-independent receptor for alpha-latrotoxin, [RH, Score=72.4, Expect=5e-12]} {Celegans: WBGene00002251, lat-1, Latrophilin-like protein 1, [Score=107, Expect=5e-23]} {Smed: dd_Smed_v6_8425_0_1, dd_Smed_v6_8425_0_1, [Score=587, Expect=1e-173]} {RNA1509_17130, RNA1509_4023, RNA1509_47993, RNA1509_50945, RNA1509_52292, RNA1509_52867} {RNA1310_254.2, RNA1509_17130, RNA1509_47993, RNA1509_50945, RNA1509_52292, RNA1509_52867} {RNA1509_17130, RNA1509_47993, RNA1509_50945, RNA1509_52292, RNA1509_52867, RNA815_85.1}
50. MligTC455_47806 2724 56.76 Mlig455_033677

Neo: -

Age: -

Region-specific R2: 3.773

Region-enriched R2: 2.504/0.00005

3.347 0.718 - 0.734 - 0.927 0.968 Mlig455_033677 {REF} {Length: 1836} {RNA1509_1605, RNA1509_16422, RNA1509_33244, RNA1509_46504} {RNA1310_30659.1, RNA1509_1605, RNA1509_16422, RNA1509_33244, RNA1509_46504} {RNA1509_1605, RNA1509_16422, RNA1509_33244, RNA1509_46504, RNA815_13807}
51. MligTC455_47190 3794 79.04 Mlig455_044419, Mlig455_044420, Mlig455_044455

Neo: -

Age: -

Region-enriched R8: 3.373/0.00004
Region-enriched R7: 2.224/0.04308

3.344 - 0.732 0.811 - 0.965 0.836

Mlig455_044419 {REF} {Length: 1036} {RNA1509_30179} {RNA1310_60147} {RNA815_30734}

Mlig455_044420 {REF} {Length: 1088} {RNA1509_30179} {RNA1310_60147} {RNA815_30734}

Mlig455_044455 {REF} {Length: 1883} {Smed: dd_Smed_v6_1588_0_1, dd_Smed_v6_1588_0_1, [Score=41.2, Expect=6e-06]} {RNA1509_30179} {RNA1310_60147, RNA1509_30179} {RNA1509_30179, RNA815_30734}
52. MligTC455_26586 477 9.94 Mlig455_061635

Neo: -

Age: -

Region-enriched R2: 1.586/0.01809

3.335 0.753 0.730 - - 0.960 0.892 Mlig455_061635 {REF} {Length: 3253} {RNA1509_19437} {RNA1310_10896, RNA1509_19437} {RNA1509_19437, RNA815_16416}
53. MligTC455_48618 1040 21.66 Mlig455_045692

Neo: -

Age: logFC(26M/2M)=-0.486

CCDC81 3.332 0.804 - 0.859 0.969 0.700 - Mlig455_045692 {REF} {Length: 4129} {Pfam: CCDC81 eukaryotic HU domain 2 [PF18289.3, score=77.1]; CCDC81 eukaryotic HU domain 1 [PF14908.8, score=72.0]; Bacterial DNA-binding protein [PF00216.23, score=21.2]; HU domain fused to wHTH, Ig, or Glycine-rich motif [PF18291.3, score=18.9]} {Human: ENSG00000149201, CCDC81, coiled-coil domain containing 81, [RH, Score=242, Expect=9e-70]} {Mouse: ENSMUSG00000039391, Ccdc81, coiled-coil domain containing 81, [Score=218, Expect=5e-61]} {Smed: dd_Smed_v6_6753_0_1, dd_Smed_v6_6753_0_1, [RH, Score=588, Expect=0.0]} {RNA1509_2273} {RNA1310_2378} {RNA815_610}
54. MligTC455_15492 69 1.44 Mlig455_022488

Neo: -

Age: Down-Up-Up

3.325 0.747 - 0.834 - 0.959 0.785 Mlig455_022488 {REF} {Length: 1351} {RNA1310_26051} {RNA815_10966}
55. MligTC455_24061 1104 23.01 Mlig455_017234

Neo: -

Age: -

SNAP25 3.32 - 0.722 0.818 - 0.971 0.809 Mlig455_017234 {REF} {Length: 1658} {Pfam: SNAP-25 family [PF00835.21, score=41.5]} {Human: ENSG00000132639, SNAP25, synaptosome associated protein 25, [Score=219, Expect=7e-72]} {Mouse: ENSMUSG00000027273, Snap25, synaptosomal-associated protein 25, [Score=219, Expect=5e-72]} {Dmel: FBgn0266720, Snap24, Synaptosomal-associated protein 24kDa, [RH, Score=228, Expect=1e-75]} {Celegans: WBGene00004364, ric-4, Synaptosomal-associated protein, [RH, Score=257, Expect=2e-87]} {Smed: dd_Smed_v6_3977_0_1, dd_Smed_v6_3977_0_1, [RH, Score=282, Expect=2e-97]} {RNA1509_25321, RNA1509_8624} {RNA1310_24253, RNA1509_25321, RNA1509_8624} {RNA1509_25321, RNA1509_8624, RNA815_10439}
56. MligTC455_53231 3817 79.52 Mlig455_029524

Neo: -

Age: -

Region-enriched R8: 1.875/0.00000
Region-enriched R7: 1.263/0.00050

Regeneration-depleted BL: -2.126
Regeneration-depleted TP: -1.952

PKD2 3.316 - 0.812 - 0.807 0.994 0.703 Mlig455_029524 {REF} {Length: 3383} {Pfam: Polycystin cation channel [PF08016.14, score=469.8]; Ion transport protein [PF00520.33, score=89.9]; EF hand [PF00036.34, score=29.0]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=19.2]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [Score=731, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=732, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=310, Expect=5e-92]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=363, Expect=5e-114]} {Smed: dd_Smed_v6_17348_0_3, dd_Smed_v6_17348_0_3, [RH, Score=748, Expect=0.0]} {RNA1509_54167} {RNA1310_10884} {RNA815_4012.1}
57. MligTC455_16609 80 1.68 Mlig455_020102

Neo: -

Age: -

WSCD2 3.311 - 0.729 0.871 - 0.758 0.953 Mlig455_020102 {REF} {Length: 980} {Pfam: WSC domain [PF01822.21, score=56.5]; PAN domain [PF00024.28, score=25.6]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=58.5, Expect=2e-09]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=58.5, Expect=1e-09]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=52.4, Expect=9e-08]} {RNA1509_46267} {RNA1310_46146} {RNA815_32275.1}
58. MligTC455_48034 2940 61.24 Mlig455_019197

Neo: -

Age: Down-Up-Down

Region-specific R2: 3.626

Region-enriched R2: 3.016/0.00000

3.296 0.793 - 0.754 - 0.799 0.950 Mlig455_019197 {REF} {Length: 837} {TRANSSPLICED} {RNA1509_18675, RNA1509_21674, RNA1509_29285, RNA1509_6143} {RNA1310_17472, RNA1509_18675, RNA1509_21674, RNA1509_29285, RNA1509_6143} {RNA1509_18675, RNA1509_21674, RNA1509_29285, RNA1509_6143, RNA815_19105}
59. MligTC455_29914 44 0.91 Mlig455_027923

Neo: -

Age: Down-Up-Down

Region-enriched R2: 8.096/0.00455

ANGPTL3 3.292 0.724 - 0.857 - 0.960 0.751 Mlig455_027923 {REF} {Length: 1663} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=70.5]} {Human: ENSG00000132855, ANGPTL3, angiopoietin like 3, [Score=60.5, Expect=9e-10]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=59.3, Expect=2e-09]; ENSG00000120332, TNN, tenascin N, [Score=58.9, Expect=3e-09]} {Mouse: ENSMUSG00000015829, Tnr, tenascin R, [Score=62.4, Expect=2e-10]} {Dmel: FBgn0031804, CG9500, [Score=76.3, Expect=6e-16]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=51.2, Expect=3e-07]} {RNA1509_53291} {RNA1310_58974} {RNA815_43288.3}
60. MligTC455_27692 1230 25.62 Mlig455_041598

Neo: -

Age: logFC(26M/2M)=-0.459

Region-enriched R7: 1.679/0.00325
Region-enriched R8: 1.607/0.03580
Region-enriched R2: 1.508/0.02284

TUBA1A 3.289 0.752 0.821 - - 0.981 0.735 Mlig455_041598 {REF} {Length: 2325} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=229.7]; Tubulin C-terminal domain [PF03953.19, score=175.5]; Tubulin domain [PF14881.8, score=18.9]} {Human: ENSG00000167552, TUBA1A, tubulin alpha 1a, [RH, Score=926, Expect=0.0]; ENSG00000123416, TUBA1B, tubulin alpha 1b, [RH, Score=923, Expect=0.0]; ENSG00000167553, TUBA1C, tubulin alpha 1c, [RH, Score=887, Expect=0.0]} {Mouse: ENSMUSG00000072235, Tuba1a, tubulin, alpha 1A, [RH, Score=926, Expect=0.0]; ENSMUSG00000023004, Tuba1b, tubulin, alpha 1B, [RH, Score=923, Expect=0.0]} {Dmel: FBgn0003884, alphaTub84B, alpha-Tubulin at 84B, [RH, Score=917, Expect=0.0]} {Celegans: WBGene00003175, mec-12, Tubulin alpha-3 chain Detyrosinated tubulin alpha-3 chain, [RH, Score=850, Expect=0.0]} {Smed: dd_Smed_v6_38_0_1, dd_Smed_v6_38_0_1, [RH, Score=924, Expect=0.0]} {RNA1509_21352, RNA1509_42319, RNA1509_9718} {RNA1310_10339.1, RNA1509_21352, RNA1509_42319} {RNA1509_21352, RNA1509_42319, RNA815_1715.1}
61. MligTC455_52570 71 1.49 Mlig455_066071

Neo: -

Age: Up-Down-Up

3.282 - 0.709 0.823 - 0.953 0.797 Mlig455_066071 {REF} {Length: 2575} {Pfam: Hemingway/CFA97 [PF13879.8, score=54.6]; Annexin [PF00191.22, score=26.1]} {Mouse: ENSMUSG00000090336, Cfap97d2, CFAP97 domain containing 2, [Score=46.6, Expect=3e-06]} {Smed: dd_Smed_v6_2676_0_1, dd_Smed_v6_2676_0_1, [Score=70.1, Expect=2e-13]} {RNA1310_29320.1} {RNA815_54680}
62. MligTC455_53232 3932 81.91 Mlig455_043077

Neo: -

Age: -

Region-enriched R8: 1.891/0.00000
Region-enriched R7: 1.329/0.00017

Regeneration-depleted BL: -2.128
Regeneration-depleted TP: -2.052

PKD2 3.282 - 0.774 - 0.814 0.991 0.703 Mlig455_043077 {REF} {Length: 3380} {Pfam: Polycystin cation channel [PF08016.14, score=472.5]; Ion transport protein [PF00520.33, score=89.3]; EF hand [PF00036.34, score=29.1]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=19.2]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [Score=733, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=733, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=310, Expect=8e-92]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=363, Expect=4e-114]} {Smed: dd_Smed_v6_17348_0_3, dd_Smed_v6_17348_0_3, [RH, Score=744, Expect=0.0]} {RNA1509_54167} {RNA1310_10884, RNA1509_54167} {RNA1509_54167, RNA815_4012.1}
63. MligTC455_16415 197 4.1 Mlig455_000401

Neo: -

Age: -

Region-enriched R2: 4.276/0.00982

ROR1 3.273 0.723 - 0.775 - 0.992 0.783 Mlig455_000401 {REF} {Length: 3780} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=233.3]; Protein kinase domain [PF00069.27, score=85.9]; Immunoglobulin I-set domain [PF07679.18, score=49.4]; Immunoglobulin domain [PF13927.8, score=46.6]; Immunoglobulin domain [PF00047.27, score=31.9]; Immunoglobulin domain [PF13895.8, score=30.0]; Fz domain [PF01392.24, score=27.6]; Kringle domain [PF00051.20, score=22.3]; Immunoglobulin V-set domain [PF07686.19, score=19.5]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [RH, Score=390, Expect=1e-119]; ENSG00000169071, ROR2, receptor tyrosine kinase like orphan receptor 2, [RH, Score=379, Expect=1e-115]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [RH, Score=386, Expect=1e-118]; ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [RH, Score=377, Expect=4e-115]} {Dmel: FBgn0010407, Ror, [Score=286, Expect=3e-84]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=285, Expect=4e-82]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [RH, Score=439, Expect=2e-139]} {RNA1509_35395} {RNA1310_13558, RNA1509_35395} {RNA1509_35395, RNA815_27446}
64. MligTC455_16233 307 6.4 Mlig455_011368

Neo: -

Age: logFC(26M/2M)=-1.958

3.262 0.706 - 0.797 - 0.967 0.792 Mlig455_011368 {REF} {Length: 1236} {RNA1509_44264} {RNA1310_62516} {RNA815_23574}
65. MligTC455_40961 1390 28.96 Mlig455_055735

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.023

Region-enriched R2: 3.902/0.00000
Region-enriched R3: 1.699/0.00333

3.262 0.796 0.702 0.961 - - 0.803 Mlig455_055735 {REF} {Length: 782} {Pfam: Pancreatic hormone peptide [PF00159.20, score=36.6]} {RNA1509_12482, RNA1509_45015, RNA1509_52082} {RNA1310_48462, RNA1509_12482, RNA1509_45015, RNA1509_52082} {RNA1509_12482, RNA1509_45015, RNA1509_52082, RNA815_25160}
66. MligTC455_31164 572 11.91 Mlig455_029609, Mlig455_045673

Neo: -

Age: -

3.26 0.728 - 0.783 - 0.973 0.776

Mlig455_029609 {REF} {Length: 746} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=39.4]} {Smed: dd_Smed_v6_22533_0_1, dd_Smed_v6_22533_0_1, [Score=48.5, Expect=1e-06]} {RNA1310_96354} {RNA815_44390}

Mlig455_045673 {REF} {Length: 2025} {RNA1509_21720} {RNA1310_14760} {RNA815_24583}
67. MligTC455_46969 2974 61.96 Mlig455_057355, Mlig455_059573

Neo: -

Age: logFC(26M/2M)=-0.329

C3orf84 3.259 - - 0.727 0.969 0.727 0.836

Mlig455_057355 {REF} {Length: 2553} {TRANSSPLICED} {Pfam: Domain of unknown function with conserved HDNR motif [PF15115.8, score=57.7]} {Human: ENSG00000236980, C3orf84, chromosome 3 open reading frame 84, [RH, Score=81.3, Expect=5e-18]} {Mouse: ENSMUSG00000050641, BC048562, cDNA sequence BC048562, [RH, Score=77.4, Expect=9e-17]} {Smed: dd_Smed_v6_6279_0_1, dd_Smed_v6_6279_0_1, [RH, Score=167, Expect=4e-51]} {RNA1509_22714} {RNA1310_1272} {RNA815_5641.1}

Mlig455_059573 {REF} {Length: 2553} {TRANSSPLICED} {Pfam: Domain of unknown function with conserved HDNR motif [PF15115.8, score=57.7]} {Human: ENSG00000236980, C3orf84, chromosome 3 open reading frame 84, [RH, Score=81.3, Expect=5e-18]} {Mouse: ENSMUSG00000050641, BC048562, cDNA sequence BC048562, [RH, Score=77.4, Expect=9e-17]} {Smed: dd_Smed_v6_6279_0_1, dd_Smed_v6_6279_0_1, [RH, Score=167, Expect=4e-51]} {RNA1509_22714} {RNA1310_1272} {RNA815_5641.1}
68. MligTC455_53036 8796 183.25 Mlig455_032587

Neo: -

Age: -

Regeneration-downregulated BL: -1.146

Regeneration-depleted BL: -1.146

3.254 - 0.845 0.710 - 0.729 0.970 Mlig455_032587 {REF} {Length: 1359} {NoTransDecoderORF} {RNA1509_2782, RNA1509_3357, RNA1509_7668} {RNA1310_40499.1, RNA1509_2782, RNA1509_3357, RNA1509_7668} {RNA1509_2782, RNA1509_3357, RNA1509_7668, RNA815_19419.1}
69. MligTC455_35259 2265 47.19 Mlig455_040978

Neo: -

Age: Up-Down-Down

Region-specific R2: 2.606

Region-enriched R2: 1.588/0.00387

ADGRL2 3.228 0.800 0.707 - - 0.967 0.754 Mlig455_040978 {REF} {Length: 10808} {TRANSSPLICED} {Pfam: PDZ domain [PF00595.26, score=86.9]; 7 transmembrane receptor (Secretin family) [PF00002.26, score=76.2]; PDZ domain [PF17820.3, score=67.3]; GPCR proteolysis site, GPS, motif [PF01825.23, score=52.3]; PDZ domain [PF13180.8, score=36.4]; ZU5 domain [PF00791.22, score=30.8]; Guanylate kinase [PF00625.23, score=22.4]} {Human: ENSG00000117114, ADGRL2, adhesion G protein-coupled receptor L2, [RH, Score=174, Expect=1e-42]} {Mouse: ENSMUSG00000034917, Tjp3, tight junction protein 3, [RH, Score=172, Expect=9e-43]} {Dmel: FBgn0262614, pyd, polychaetoid, [RH, Score=232, Expect=8e-61]} {Celegans: WBGene00013683, zoo-1, ZO-1 (Zonula Occludens tight junctional protein) Ortholog, [Score=174, Expect=4e-43]} {Smed: dd_Smed_v6_8425_0_1, dd_Smed_v6_8425_0_1, [RH, Score=833, Expect=0.0]} {RNA1509_17602, RNA1509_52679, RNA1509_58629} {RNA1310_236.2, RNA1509_17602, RNA1509_58629} {RNA1509_17602, RNA1509_58629, RNA815_77.1}
70. MligTC455_39481 461 9.6 Mlig455_056703, Mlig455_060318

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.222

ANGPTL1 3.216 0.711 - 0.764 - 0.957 0.784

Mlig455_056703 {REF} {Length: 1114} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=79.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=89.4, Expect=1e-19]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=85.1, Expect=3e-18]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=91.3, Expect=2e-20]} {Dmel: FBgn0033312, CG8642, [Score=82.4, Expect=1e-17]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=76.3, Expect=1e-15]} {RNA1310_31288} {RNA815_20497.1}

Mlig455_060318 {REF} {Length: 1175} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=112.7]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=106, Expect=2e-25]; ENSG00000171819, ANGPTL7, angiopoietin like 7, [Score=105, Expect=6e-26]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=109, Expect=1e-26]} {Dmel: FBgn0034160, CG5550, [Score=96.3, Expect=2e-23]} {Celegans: WBGene00016769, C49C8.5, [Score=47.0, Expect=9e-06]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=88.2, Expect=2e-19]} {RNA1310_31288} {RNA815_20497.1}
71. MligTC455_54338 49 1.02 Mlig455_056485

Neo: -

Age: Up-Down-Down

PKDREJ 3.209 0.727 0.710 - - 0.984 0.788 Mlig455_056485 {REF} {Length: 11174} {Pfam: Polycystin cation channel [PF08016.14, score=290.0]; REJ domain [PF02010.17, score=90.7]; PLAT/LH2 domain [PF01477.25, score=67.3]; PKD domain [PF00801.22, score=47.7]; Ion transport protein [PF00520.33, score=40.1]; PKD domain [PF18911.2, score=29.8]; GPCR proteolysis site, GPS, motif [PF01825.23, score=27.4]; WSC domain [PF01822.21, score=27.0]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=280, Expect=1e-74]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=307, Expect=8e-83]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=151, Expect=3e-36]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [RH, Score=302, Expect=1e-81]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [RH, Score=1844, Expect=0.0]} {RNA1509_16432} {RNA1310_1236} {RNA815_2411}
72. MligTC455_23957 33 0.68 Mlig455_015196, Mlig455_068736

Neo: -

Age: -

Region-enriched R2: 7.683/0.01527

3.208 - 0.707 0.742 - 0.962 0.797

Mlig455_015196 {REF} {Length: 1138} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=63.8]} {RNA1509_30941} {RNA1310_34740} {RNA815_15663}

Mlig455_068736 {REF} {Length: 1580} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=64.0]} {RNA1310_32395.1} {RNA815_15663}
73. MligTC455_48848 282 5.87 Mlig455_005151, Mlig455_021613

Neo: -

Age: -

Region-specific R2: 4.764

Region-enriched R2: 5.813/0.00000

SYT3 3.181 0.702 - 0.979 - 0.766 0.734

Mlig455_005151 {REF} {Length: 1574} {Pfam: C2 domain [PF00168.32, score=55.1]} {Human: ENSG00000213023, SYT3, synaptotagmin 3, [Score=68.6, Expect=5e-12]; ENSG00000011347, SYT7, synaptotagmin 7, [Score=67.0, Expect=1e-11]} {Mouse: ENSMUSG00000030731, Syt3, synaptotagmin III, [Score=69.3, Expect=2e-12]} {Dmel: FBgn0261089, Sytalpha, Synaptotagmin alpha, [Score=63.2, Expect=1e-10]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=66.6, Expect=5e-12]} {Smed: dd_Smed_v6_25279_0_1, dd_Smed_v6_25279_0_1, [Score=85.1, Expect=2e-18]} {RNA1310_20857} {RNA815_8396}

Mlig455_021613 {REF} {Length: 1574} {Pfam: C2 domain [PF00168.32, score=55.1]} {Human: ENSG00000213023, SYT3, synaptotagmin 3, [Score=68.6, Expect=5e-12]; ENSG00000011347, SYT7, synaptotagmin 7, [Score=67.0, Expect=1e-11]} {Mouse: ENSMUSG00000030731, Syt3, synaptotagmin III, [Score=69.3, Expect=2e-12]} {Dmel: FBgn0261089, Sytalpha, Synaptotagmin alpha, [Score=63.2, Expect=1e-10]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=66.6, Expect=5e-12]} {Smed: dd_Smed_v6_25279_0_1, dd_Smed_v6_25279_0_1, [Score=85.1, Expect=2e-18]} {RNA1310_20857} {RNA815_8396}
74. MligTC455_48022 1337 27.86 Mlig455_045267, Mlig455_069186

Neo: -

Age: -

Region-enriched R2: 2.130/0.00146

3.18 0.701 0.708 0.795 - 0.976 -

Mlig455_045267 {REF} {Length: 3628} {Pfam: Ankyrin repeats (many copies) [PF13857.8, score=29.5]; Ankyrin repeats (many copies) [PF13637.8, score=28.4]; Ankyrin repeats (3 copies) [PF12796.9, score=28.3]; Ankyrin repeat [PF13606.8, score=23.5]} {Celegans: WBGene00009375, F34D10.6, [Score=57.0, Expect=6e-08]} {Smed: dd_Smed_v6_5594_0_3, dd_Smed_v6_5594_0_3, [Score=58.5, Expect=1e-08]} {RNA1509_17412, RNA1509_32079} {RNA1310_5952, RNA1509_17412, RNA1509_32079} {RNA1509_17412, RNA1509_32079, RNA815_2323}

Mlig455_069186 {REF} {Length: 3598} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=30.4]; Ankyrin repeats (3 copies) [PF12796.9, score=30.1]; Ankyrin repeats (many copies) [PF13857.8, score=29.5]; Ankyrin repeat [PF13606.8, score=24.1]} {Celegans: WBGene00009375, F34D10.6, [Score=56.6, Expect=6e-08]} {Smed: dd_Smed_v6_5594_0_4, dd_Smed_v6_5594_0_4, [Score=59.3, Expect=7e-09]} {RNA1509_52963} {RNA1310_5952, RNA1509_52963} {RNA1509_52963, RNA815_2323}
75. MligTC455_32445 285 5.93 Mlig455_041727, Mlig455_042282

Neo: -

Age: -

ANK2 3.17 0.709 0.736 - - 0.980 0.745

Mlig455_041727 {REF} {Length: 4931} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=276.7]; Ankyrin repeats (many copies) [PF13637.8, score=238.3]; Ankyrin repeat [PF00023.32, score=223.0]; Ankyrin repeats (many copies) [PF13857.8, score=214.9]; Ankyrin repeat [PF13606.8, score=201.4]; Ion transport protein [PF00520.33, score=46.6]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=211, Expect=1e-54]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=290, Expect=2e-80]} {Dmel: FBgn0011747, Ank, Ankyrin, [Score=210, Expect=2e-54]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=489, Expect=7e-151]} {Smed: dd_Smed_v6_6201_0_2, dd_Smed_v6_6201_0_2, [RH, Score=745, Expect=0.0]} {RNA1509_18945} {RNA1310_1506.1, RNA1509_18945} {RNA1509_18945, RNA815_450.1}

Mlig455_042282 {REF} {Length: 4940} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=273.8]; Ankyrin repeats (many copies) [PF13637.8, score=232.4]; Ankyrin repeat [PF00023.32, score=218.4]; Ankyrin repeats (many copies) [PF13857.8, score=210.6]; Ankyrin repeat [PF13606.8, score=197.5]; Ion transport protein [PF00520.33, score=46.6]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=214, Expect=2e-55]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=204, Expect=1e-52]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=201, Expect=2e-51]} {Dmel: FBgn0011747, Ank, Ankyrin, [Score=205, Expect=6e-53]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=487, Expect=5e-150]} {Smed: dd_Smed_v6_6201_0_2, dd_Smed_v6_6201_0_2, [RH, Score=736, Expect=0.0]} {RNA1509_18945} {RNA1310_1506.1} {RNA815_8298}
76. MligTC455_47080 362 7.54 Mlig455_037356

Neo: -

Age: -

Region-enriched R2: 2.691/0.00566

SSUH2 3.169 0.717 0.702 - - 0.972 0.778 Mlig455_037356 {REF} {Length: 1984} {Pfam: DnaJ central domain [PF00684.21, score=20.9]} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=189, Expect=3e-56]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=156, Expect=5e-44]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=90.9, Expect=7e-20]} {RNA1509_29510} {RNA1310_15488, RNA1509_29510} {RNA1509_29510, RNA815_5650}
77. MligTC455_50567 146 3.04 Mlig455_012858

Neo: -

Age: -

Region-specific R2: 6.162

Region-enriched R2: 5.988/0.01054

2.851 - - 0.909 - 0.990 0.952 Mlig455_012858 {REF} {Length: 1282} {Pfam: F5/8 type C domain [PF00754.27, score=27.5]} {Smed: dd_Smed_v6_36585_0_1, dd_Smed_v6_36585_0_1, [RH, Score=64.3, Expect=4e-12]} {RNA1310_34633} {RNA815_12537}
78. MligTC455_17561 189 3.94 Mlig455_020268

Neo: -

Age: -

Region-enriched R2: 4.198/0.00004

NECAB3 2.817 - - 0.882 - 0.975 0.960 Mlig455_020268 {REF} {Length: 1518} {Pfam: EF hand [PF00036.34, score=34.0]; EF-hand domain [PF13405.8, score=33.4]; EF-hand domain pair [PF13833.8, score=29.2]; EF-hand domain pair [PF13499.8, score=28.3]; Antibiotic biosynthesis monooxygenase [PF03992.18, score=22.0]; EF hand [PF13202.8, score=21.3]} {Human: ENSG00000125967, NECAB3, N-terminal EF-hand calcium binding protein 3, [RH, Score=189, Expect=7e-57]; ENSG00000123119, NECAB1, N-terminal EF-hand calcium binding protein 1, [RH, Score=186, Expect=1e-55]} {Mouse: ENSMUSG00000040536, Necab1, N-terminal EF-hand calcium binding protein 1, [RH, Score=192, Expect=6e-58]; ENSMUSG00000027489, Necab3, N-terminal EF-hand calcium binding protein 3, [RH, Score=191, Expect=9e-58]} {RNA1509_46831} {RNA1310_24461, RNA1509_46831} {RNA1509_46831, RNA815_25216}
79. MligTC455_48051 729 15.19 Mlig455_037292, Mlig455_037331

Neo: -

Age: logFC(26M/2M)=-0.645

Region-enriched R2: 2.891/0.00005

AGBL3 2.796 - - 0.894 0.977 0.925 -

Mlig455_037292 {REF} {Length: 4360} {Pfam: Zinc carboxypeptidase [PF00246.26, score=66.0]; Cytosolic carboxypeptidase N-terminal domain [PF18027.3, score=64.0]} {Human: ENSG00000146856, AGBL3, ATP/GTP binding protein like 3, [Score=547, Expect=1e-176]; ENSG00000165923, AGBL2, ATP/GTP binding protein like 2, [Score=521, Expect=5e-167]; ENSG00000285501, AGBL2, ATP/GTP binding protein like 2, [Score=521, Expect=5e-167]} {Mouse: ENSMUSG00000038836, Agbl3, ATP/GTP binding protein-like 3, [Score=542, Expect=9e-174]; ENSMUSG00000040812, Agbl2, ATP/GTP binding protein-like 2, [Score=528, Expect=5e-170]} {Dmel: FBgn0265726, Nna1, Nna1 carboxypeptidase, [Score=489, Expect=3e-157]} {Celegans: WBGene00018995, ccpp-1, Cytosolic carboxypeptidase 1, [Score=276, Expect=6e-77]} {Smed: dd_Smed_v6_13450_0_1, dd_Smed_v6_13450_0_1, [Score=533, Expect=2e-171]} {RNA1509_25820} {RNA1310_2132.1} {RNA815_1862}

Mlig455_037331 {REF} {Length: 4775} {Pfam: Cytosolic carboxypeptidase N-terminal domain [PF18027.3, score=70.1]; Zinc carboxypeptidase [PF00246.26, score=65.7]} {Human: ENSG00000146856, AGBL3, ATP/GTP binding protein like 3, [RH, Score=575, Expect=0.0]} {Mouse: ENSMUSG00000040812, Agbl2, ATP/GTP binding protein-like 2, [RH, Score=569, Expect=0.0]; ENSMUSG00000038836, Agbl3, ATP/GTP binding protein-like 3, [RH, Score=568, Expect=0.0]} {Dmel: FBgn0265726, Nna1, Nna1 carboxypeptidase, [Score=520, Expect=2e-168]} {Celegans: WBGene00018995, ccpp-1, Cytosolic carboxypeptidase 1, [Score=290, Expect=1e-81]} {Smed: dd_Smed_v6_13450_0_1, dd_Smed_v6_13450_0_1, [RH, Score=604, Expect=0.0]} {RNA1509_25820} {RNA1310_2132.1} {RNA815_1862}
80. MligTC455_19338 2431 50.65 Mlig455_022165

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.390

Region-specific R2: 3.133

Region-enriched R2: 2.312/0.00036

2.791 - - 0.939 - 0.953 0.899 Mlig455_022165 {REF} {Length: 1038} {RNA1509_18606, RNA1509_6523} {RNA1310_50737, RNA1509_18606, RNA1509_6523} {RNA1509_18606, RNA1509_6523, RNA815_26880}
81. MligTC455_47875 72 1.5 Mlig455_067941

Neo: -

Age: -

2.79 - - 0.902 - 0.908 0.980 Mlig455_067941 {REF} {Length: 1399} {Smed: dd_Smed_v6_3944_0_1, dd_Smed_v6_3944_0_1, [Score=97.8, Expect=7e-26]} {RNA1509_55952} {RNA1310_12426} {RNA815_33214}
82. MligTC455_53844 1403 29.24 Mlig455_051626

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.540

2.771 - 0.944 - - 0.983 0.844 Mlig455_051626 {REF} {Length: 1671} {RNA1509_15580} {RNA1310_24090} {RNA815_10676.2}
83. MligTC455_19824 108 2.25 Mlig455_063413

Neo: -

Age: Down-Up-Down

2.758 - - 0.890 - 0.886 0.982 Mlig455_063413 {REF} {Length: 1101} {RNA1509_53920} {RNA1310_31235} {RNA815_3217.1}
84. MligTC455_33842 492 10.26 Mlig455_004899

Neo: -

Age: -

Region-enriched R2: 2.178/0.01972

CDKL1 2.757 - - 0.905 0.976 0.876 - Mlig455_004899 {REF} {Length: 2500} {Pfam: Protein kinase domain [PF00069.27, score=247.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=116.6]; Haspin like kinase domain [PF12330.10, score=18.7]; ABC1 atypical kinase-like domain [PF03109.18, score=18.6]} {Human: ENSG00000100490, CDKL1, cyclin dependent kinase like 1, [RH, Score=429, Expect=3e-150]; ENSG00000205111, CDKL4, cyclin dependent kinase like 4, [RH, Score=422, Expect=2e-148]} {Mouse: ENSMUSG00000020990, Cdkl1, cyclin-dependent kinase-like 1 (CDC2-related kinase), [RH, Score=432, Expect=7e-152]; ENSMUSG00000033966, Cdkl4, cyclin-dependent kinase-like 4, [RH, Score=423, Expect=3e-148]} {Dmel: FBgn0031730, CG7236, [RH, Score=381, Expect=6e-131]} {Celegans: WBGene00012779, cdkl-1, Cyclin-Dependent Kinase-Like, [RH, Score=396, Expect=4e-136]} {Smed: dd_Smed_v6_9353_0_1, dd_Smed_v6_9353_0_1, [RH, Score=481, Expect=5e-171]} {RNA1509_19679} {RNA1310_6686.1} {RNA815_5397}
85. MligTC455_38288 5006 104.28 Mlig455_045260, Mlig455_069180

Neo: -

Age: logFC(26M/2M)=0.302

Region-specific R2: 4.563

Region-enriched R2: 3.648/0.00002

RNF217 2.755 - - 0.886 - 0.888 0.981

Mlig455_045260 {REF} {Length: 2327} {Pfam: IBR domain, a half RING-finger domain [PF01485.23, score=53.3]} {Human: ENSG00000146373, RNF217, ring finger protein 217, [Score=129, Expect=8e-31]} {Mouse: ENSMUSG00000063760, Rnf217, ring finger protein 217, [Score=124, Expect=1e-29]} {Dmel: FBgn0031857, LUBEL, Linear Ubiquitin E3 ligase, [Score=56.2, Expect=1e-07]} {Smed: dd_Smed_v6_7110_0_1, dd_Smed_v6_7110_0_1, [Score=114, Expect=1e-26]} {RNA1509_27317} {RNA1310_23955} {RNA815_6068}

Mlig455_069180 {REF} {Length: 2719} {Pfam: IBR domain, a half RING-finger domain [PF01485.23, score=54.2]} {Human: ENSG00000146373, RNF217, ring finger protein 217, [Score=130, Expect=3e-31]} {Mouse: ENSMUSG00000063760, Rnf217, ring finger protein 217, [Score=125, Expect=4e-30]} {Dmel: FBgn0031857, LUBEL, Linear Ubiquitin E3 ligase, [Score=55.8, Expect=1e-07]} {Smed: dd_Smed_v6_7110_0_1, dd_Smed_v6_7110_0_1, [Score=113, Expect=3e-26]} {RNA1509_27317} {RNA1310_23955} {RNA815_6068}
86. MligTC455_47874 67 1.4 Mlig455_000340

Neo: -

Age: -

2.738 - - 0.858 - 0.908 0.972 Mlig455_000340 {REF} {Length: 1412} {Smed: dd_Smed_v6_3944_0_1, dd_Smed_v6_3944_0_1, [Score=97.4, Expect=9e-26]} {RNA1509_55952} {RNA1310_12426} {RNA815_33214}
87. MligTC455_20443 430 8.96 Mlig455_010917, Mlig455_033173

Neo: -

Age: -

Region-specific R2: 4.126

Region-enriched R2: 3.438/0.00019

CFAP77 2.733 - - 0.848 - 0.928 0.957

Mlig455_010917 {REF} {Length: 1338} {Pfam: Domain of unknown function (DUF4483) [PF14825.8, score=38.6]} {Human: ENSG00000188523, CFAP77, cilia and flagella associated protein 77, [Score=47.8, Expect=3e-06]} {Mouse: ENSMUSG00000079502, Cfap77, cilia and flagella associated protein 77, [Score=50.1, Expect=4e-07]} {Smed: dd_Smed_v6_5179_0_1, dd_Smed_v6_5179_0_1, [Score=84.3, Expect=4e-20]} {RNA1509_46220} {RNA1310_36457, RNA1509_46220} {RNA1509_46220, RNA815_17196}

Mlig455_033173 {REF} {Length: 978} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4483) [PF14825.8, score=19.5]} {RNA1509_46220} {RNA1310_36457} {RNA815_17196}
88. MligTC455_42035 64 1.34 Mlig455_005576

Neo: -

Age: -

LGR4 2.73 - - 0.917 - 0.991 0.822 Mlig455_005576 {REF} {Length: 2995} {Pfam: Leucine rich repeat [PF13855.8, score=100.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=48.4]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=38.5]; Leucine Rich Repeat [PF00560.35, score=22.1]; Leucine-rich repeat [PF14580.8, score=18.6]} {Human: ENSG00000205213, LGR4, leucine rich repeat containing G protein-coupled receptor 4, [Score=68.6, Expect=1e-11]; ENSG00000198799, LRIG2, leucine rich repeats and immunoglobulin like domains 2, [Score=68.2, Expect=1e-11]; ENSG00000099769, IGFALS, insulin like growth factor binding protein acid labile subunit, [Score=68.2, Expect=1e-11]; ENSG00000172061, LRRC15, leucine rich repeat containing 15, [Score=67.8, Expect=2e-11]; ENSG00000011465, DCN, decorin, [Score=66.2, Expect=2e-11]; ENSG00000186105, LRRC70, leucine rich repeat containing 70, [Score=66.2, Expect=5e-11]} {Mouse: ENSMUSG00000050199, Lgr4, leucine-rich repeat-containing G protein-coupled receptor 4, [Score=68.9, Expect=6e-12]; ENSMUSG00000032913, Lrig2, leucine-rich repeats and immunoglobulin-like domains 2, [Score=65.9, Expect=5e-11]; ENSMUSG00000052316, Lrrc15, leucine rich repeat containing 15, [Score=65.5, Expect=5e-11]} {Dmel: FBgn0003255, rk, rickets, [Score=65.1, Expect=7e-11]} {Celegans: WBGene00019351, lron-7, ELRR (Extracellular Leucine-Rich Repeat) ONly, [Score=61.2, Expect=6e-10]} {Smed: dd_Smed_v6_19180_0_1, dd_Smed_v6_19180_0_1, [Score=47.4, Expect=1e-05]} {RNA1310_20141.1} {RNA815_7925.1}
89. MligTC455_29049 441 9.18 Mlig455_042244

Neo: -

Age: -

Region-enriched R2: 4.677/0.00000
Region-enriched R3: 2.595/0.01002

RASGRF1 2.724 - - 0.817 0.947 0.960 - Mlig455_042244 {REF} {Length: 6465} {Pfam: RasGEF domain [PF00617.21, score=193.2]; RhoGEF domain [PF00621.22, score=119.3]; PH domain [PF00169.31, score=86.7]; RasGEF N-terminal motif [PF00618.22, score=68.4]; Pleckstrin homology domain [PF15413.8, score=22.6]} {Human: ENSG00000058335, RASGRF1, Ras protein specific guanine nucleotide releasing factor 1, [RH, Score=763, Expect=0.0]; ENSG00000113319, RASGRF2, Ras protein specific guanine nucleotide releasing factor 2, [RH, Score=739, Expect=0.0]} {Mouse: ENSMUSG00000032356, Rasgrf1, RAS protein-specific guanine nucleotide-releasing factor 1, [RH, Score=763, Expect=0.0]} {Dmel: FBgn0001965, Sos, Son of sevenless, [Score=164, Expect=3e-40]} {Celegans: WBGene00004947, sos-1, Son of sevenless homolog, [Score=118, Expect=3e-26]} {Smed: dd_Smed_v6_18313_0_2, dd_Smed_v6_18313_0_2, [RH, Score=1137, Expect=0.0]} {RNA1509_15697} {RNA1310_2543.1} {RNA815_8228.1}
90. MligTC455_49004 1711 35.64 Mlig455_040452, Mlig455_042848, Mlig455_043610

Neo: -

Age: logFC(26M/2M)=-0.274

Region-enriched R2: 1.355/0.00285

CCDC180 2.715 - - - 0.973 0.910 0.832

Mlig455_040452 {REF} {Length: 5565} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4455) [PF14643.8, score=418.0]; Domain of unknown function (DUF4456) [PF14644.8, score=172.8]} {Human: ENSG00000197816, CCDC180, coiled-coil domain containing 180, [Score=410, Expect=3e-117]} {Mouse: ENSMUSG00000035539, Ccdc180, coiled-coil domain containing 180, [RH, Score=275, Expect=3e-74]} {Smed: dd_Smed_v6_12302_0_1, dd_Smed_v6_12302_0_1, [Score=399, Expect=4e-116]} {RNA1509_8832} {RNA1310_898.2} {RNA815_672.1}

Mlig455_042848 {REF} {Length: 5466} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4455) [PF14643.8, score=419.7]} {Human: ENSG00000197816, CCDC180, coiled-coil domain containing 180, [Score=274, Expect=1e-74]} {Mouse: ENSMUSG00000035539, Ccdc180, coiled-coil domain containing 180, [RH, Score=275, Expect=4e-75]} {Smed: dd_Smed_v6_12302_0_1, dd_Smed_v6_12302_0_1, [Score=254, Expect=7e-69]} {RNA1509_8832} {RNA1310_898.1} {RNA815_672.1}

Mlig455_043610 {REF} {Length: 5567} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4455) [PF14643.8, score=413.1]; Domain of unknown function (DUF4456) [PF14644.8, score=171.2]} {Human: ENSG00000197816, CCDC180, coiled-coil domain containing 180, [RH, Score=405, Expect=1e-115]} {Mouse: ENSMUSG00000035539, Ccdc180, coiled-coil domain containing 180, [RH, Score=270, Expect=7e-73]} {Smed: dd_Smed_v6_12302_0_1, dd_Smed_v6_12302_0_1, [RH, Score=398, Expect=1e-115]} {RNA1509_8832} {RNA1310_898.2} {RNA815_672.1}
91. MligTC455_19325 1452 30.24 Mlig455_036471, Mlig455_056256

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.575

Region-enriched R2: 2.298/0.00464
Region-enriched R8: 2.134/0.01396

2.704 - 0.958 - - 0.878 0.868

Mlig455_036471 {REF} {Length: 598} {RNA1509_40294} {RNA1310_65876} {RNA815_35457}

Mlig455_056256 {REF} {Length: 599} {RNA1509_40294} {RNA1310_65876, RNA1509_40294} {RNA1509_40294, RNA815_35457}
92. MligTC455_46795 785 16.35 Mlig455_000535

Neo: -

Age: logFC(26M/2M)=-0.364

Region-enriched R2: 1.672/0.01916

HTR1B 2.704 - - 0.921 0.955 0.828 - Mlig455_000535 {REF} {Length: 4573} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=255.2]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=53.3]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=23.4]; Family of unknown function (DUF5684) [PF18936.2, score=19.6]} {Human: ENSG00000135312, HTR1B, 5-hydroxytryptamine receptor 1B, [RH, Score=243, Expect=3e-75]} {Mouse: ENSMUSG00000021721, Htr1a, 5-hydroxytryptamine (serotonin) receptor 1A, [Score=251, Expect=3e-78]} {Dmel: FBgn0004573, 5-HT7, 5-hydroxytryptamine (serotonin) receptor 7, [RH, Score=276, Expect=2e-86]} {Celegans: WBGene00004780, ser-7, SERotonin/octopamine receptor family, [RH, Score=221, Expect=1e-66]} {Smed: dd_Smed_v6_5341_0_1, dd_Smed_v6_5341_0_1, [RH, Score=412, Expect=2e-140]} {RNA1509_11749, RNA1509_13593, RNA1509_37815} {RNA1310_3896.1, RNA1509_11749, RNA1509_13593, RNA1509_37815} {RNA1509_11749, RNA1509_13593, RNA1509_37815, RNA815_3010}
93. MligTC455_27649 366 7.62 Mlig455_017718, Mlig455_057045

Neo: -

Age: logFC(26M/2M)=0.439

ADAM9 2.699 - - 0.820 - 0.973 0.906

Mlig455_017718 {REF} {Length: 3325} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=133.0]; Disintegrin [PF00200.25, score=68.9]; Metallo-peptidase family M12 [PF13688.8, score=68.7]; ADAM cysteine-rich [PF08516.14, score=58.7]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=52.3]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=44.6]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=32.0]} {Human: ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [RH, Score=272, Expect=2e-78]; ENSG00000151651, ADAM8, ADAM metallopeptidase domain 8, [RH, Score=268, Expect=1e-76]} {Mouse: ENSMUSG00000031555, Adam9, a disintegrin and metallopeptidase domain 9 (meltrin gamma), [RH, Score=276, Expect=2e-79]} {Dmel: FBgn0265140, Meltrin, [Score=262, Expect=7e-73]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [RH, Score=263, Expect=9e-75]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=247, Expect=2e-68]} {RNA1509_19133, RNA1509_24635, RNA1509_4260, RNA1509_50111} {RNA1310_4299.1, RNA1509_19133, RNA1509_24635, RNA1509_50111} {RNA1509_19133, RNA1509_24635, RNA1509_50111, RNA815_11215.1}

Mlig455_057045 {REF} {Length: 3286} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=133.0]; Disintegrin [PF00200.25, score=69.2]; Metallo-peptidase family M12 [PF13688.8, score=68.8]; ADAM cysteine-rich [PF08516.14, score=58.7]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=52.3]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=44.6]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=32.0]} {Human: ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [RH, Score=273, Expect=2e-78]; ENSG00000151651, ADAM8, ADAM metallopeptidase domain 8, [RH, Score=268, Expect=7e-77]} {Mouse: ENSMUSG00000031555, Adam9, a disintegrin and metallopeptidase domain 9 (meltrin gamma), [RH, Score=280, Expect=5e-81]} {Dmel: FBgn0265140, Meltrin, [Score=259, Expect=5e-73]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [RH, Score=263, Expect=8e-75]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=247, Expect=2e-68]} {RNA1509_22944, RNA1509_4260} {RNA1310_4299.1, RNA1509_22944, RNA1509_4260} {RNA1509_22944, RNA1509_4260, RNA815_11215.1}
94. MligTC455_23150 3195 66.56 Mlig455_009524, Mlig455_009530

Neo: -

Age: -

Region-enriched R2: 3.504/0.00000
Region-enriched R3: 1.656/0.02560

CDK16 2.694 0.834 - - - 0.907 0.953

Mlig455_009524 {REF} {Length: 3287} {Pfam: Protein kinase domain [PF00069.27, score=218.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.2]} {Human: ENSG00000102225, CDK16, cyclin dependent kinase 16, [RH, Score=463, Expect=7e-159]; ENSG00000059758, CDK17, cyclin dependent kinase 17, [RH, Score=447, Expect=2e-151]} {Mouse: ENSMUSG00000031065, Cdk16, cyclin-dependent kinase 16, [RH, Score=464, Expect=2e-158]; ENSMUSG00000020015, Cdk17, cyclin-dependent kinase 17, [RH, Score=449, Expect=2e-152]} {Dmel: FBgn0005640, Eip63E, Ecdysone-induced protein 63E, [Score=362, Expect=2e-118]} {Celegans: WBGene00003961, pct-1, Cyclin-dependent kinase 17, [RH, Score=417, Expect=3e-138]} {Smed: dd_Smed_v6_4172_0_4, dd_Smed_v6_4172_0_4, [RH, Score=449, Expect=6e-151]} {RNA1509_23462} {RNA1310_21506} {RNA815_9702}

Mlig455_009530 {REF} {Length: 3384} {Pfam: Protein kinase domain [PF00069.27, score=208.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.4]; Haspin like kinase domain [PF12330.10, score=17.8]} {Human: ENSG00000102225, CDK16, cyclin dependent kinase 16, [Score=432, Expect=5e-147]} {Mouse: ENSMUSG00000031065, Cdk16, cyclin-dependent kinase 16, [Score=431, Expect=4e-146]} {Dmel: FBgn0005640, Eip63E, Ecdysone-induced protein 63E, [Score=329, Expect=9e-107]} {Celegans: WBGene00003961, pct-1, Cyclin-dependent kinase 17, [Score=392, Expect=2e-130]} {Smed: dd_Smed_v6_4172_0_4, dd_Smed_v6_4172_0_4, [Score=411, Expect=6e-137]} {RNA1509_23462} {RNA1310_21506} {RNA815_9702}
95. MligTC455_39736 474 9.86 Mlig455_014716

Neo: -

Age: Up-Down-Up

2.692 - - - 0.974 0.914 0.804 Mlig455_014716 {REF} {Length: 3097} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4537) [PF15057.8, score=61.8]; von Willebrand factor type A domain [PF13768.8, score=19.6]} {Smed: dd_Smed_v6_10837_0_1, dd_Smed_v6_10837_0_1, [RH, Score=97.4, Expect=1e-20]} {RNA1509_28750} {RNA1310_4730} {RNA815_8808}
96. MligTC455_42840 147 3.06 Mlig455_003645

Neo: -

Age: -

2.692 - - 0.756 - 0.959 0.977 Mlig455_003645 {REF} {Length: 1270} {RNA1509_48973} {RNA1310_36721} {RNA815_36286}
97. MligTC455_49579 654 13.62 Mlig455_042523

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.646

Region-enriched R2: 1.286/0.04858

ANO7 2.688 - - 0.783 - 0.958 0.947 Mlig455_042523 {REF} {Length: 4425} {Pfam: Calcium-activated chloride channel [PF04547.14, score=254.3]; Dimerisation domain of Ca+-activated chloride-channel, anoctamin [PF16178.7, score=23.0]} {Human: ENSG00000146205, ANO7, anoctamin 7, [Score=118, Expect=3e-26]} {Mouse: ENSMUSG00000034107, Ano7, anoctamin 7, [Score=124, Expect=4e-28]} {Dmel: FBgn0030349, CG10353, [Score=119, Expect=7e-27]} {Celegans: WBGene00010138, anoh-1, Anoctamin, [Score=161, Expect=4e-40]} {Smed: dd_Smed_v6_6514_0_4, dd_Smed_v6_6514_0_4, [Score=127, Expect=2e-29]} {RNA1509_21269} {RNA1310_4099.1} {RNA815_1067}
98. MligTC455_19229 3397 70.77 Mlig455_003179, Mlig455_003381

Neo: -

Age: logFC(26M/2M)=-0.346

TCTE1 2.687 - - 0.800 0.974 0.913 -

Mlig455_003179 {REF} {Length: 2512} {Pfam: Leucine Rich repeat [PF13516.8, score=60.4]; Leucine Rich Repeat [PF00560.35, score=21.2]; Leucine Rich repeats (2 copies) [PF12799.9, score=20.6]} {Human: ENSG00000146221, TCTE1, t-complex-associated-testis-expressed 1, [RH, Score=414, Expect=5e-140]} {Mouse: ENSMUSG00000023949, Tcte1, t-complex-associated testis expressed 1, [RH, Score=410, Expect=2e-138]} {Celegans: WBGene00009201, F28C1.3, Protein phosphatase 1 regulatory subunit 37 homolog, [Score=54.3, Expect=2e-07]} {Smed: dd_Smed_v6_12524_0_1, dd_Smed_v6_12524_0_1, [RH, Score=477, Expect=4e-164]} {RNA1509_3507} {RNA1310_14006, RNA1509_3507} {RNA1509_3507, RNA815_5380}

Mlig455_003381 {REF} {Length: 2163} {Pfam: Leucine Rich repeat [PF13516.8, score=60.4]; Leucine Rich Repeat [PF00560.35, score=21.0]; Leucine Rich repeats (2 copies) [PF12799.9, score=20.6]} {Human: ENSG00000146221, TCTE1, t-complex-associated-testis-expressed 1, [RH, Score=415, Expect=4e-140]} {Mouse: ENSMUSG00000023949, Tcte1, t-complex-associated testis expressed 1, [RH, Score=410, Expect=2e-138]} {Celegans: WBGene00009201, F28C1.3, Protein phosphatase 1 regulatory subunit 37 homolog, [Score=54.3, Expect=2e-07]} {Smed: dd_Smed_v6_12524_0_1, dd_Smed_v6_12524_0_1, [RH, Score=477, Expect=3e-164]} {RNA1509_3507, RNA1509_37235} {RNA1310_14006, RNA1509_37235} {RNA1509_37235, RNA815_5380}
99. MligTC455_18564 196 4.08 Mlig455_063527

Neo: -

Age: -

Region-enriched R2: 2.416/0.01839

PRKG2 2.68 - 0.953 - - 0.960 0.767 Mlig455_063527 {REF} {Length: 2971} {Pfam: Protein kinase domain [PF00069.27, score=212.4]; Cyclic nucleotide-binding domain [PF00027.31, score=135.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=103.7]; Kinase-like [PF14531.8, score=24.8]} {Human: ENSG00000138669, PRKG2, protein kinase cGMP-dependent 2, [RH, Score=653, Expect=0.0]} {Mouse: ENSMUSG00000029334, Prkg2, protein kinase, cGMP-dependent, type II, [RH, Score=651, Expect=0.0]} {Dmel: FBgn0000442, Pkg21D, Protein kinase, cGMP-dependent at 21D, [RH, Score=662, Expect=0.0]} {Celegans: WBGene00001173, egl-4, cGMP-dependent protein kinase egl-4, [Score=655, Expect=0.0]} {Smed: dd_Smed_v6_6967_0_1, dd_Smed_v6_6967_0_1, [RH, Score=645, Expect=0.0]} {RNA1509_38353} {RNA1310_8466, RNA1509_38353} {RNA1509_38353, RNA815_6313}
100. MligTC455_42227 1213 25.28 Mlig455_004225, Mlig455_031049

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.914/0.00168

LRGUK 2.677 - - 0.861 0.960 0.856 -

Mlig455_004225 {REF} {Length: 3526} {Pfam: Guanylate kinase [PF00625.23, score=97.8]; Leucine rich repeat [PF13855.8, score=83.2]; Leucine Rich repeats (2 copies) [PF12799.9, score=81.7]; Leucine-rich repeat [PF14580.8, score=68.6]; Leucine Rich repeat [PF13516.8, score=23.6]} {Human: ENSG00000155530, LRGUK, leucine rich repeats and guanylate kinase domain containing, [RH, Score=416, Expect=7e-131]} {Mouse: ENSMUSG00000056215, Lrguk, leucine-rich repeats and guanylate kinase domain containing, [RH, Score=429, Expect=3e-139]} {Dmel: FBgn0036099, CG11811, [Score=107, Expect=8e-26]} {Celegans: WBGene00011637, sds-22, Protein phosphatase 1 regulatory subunit SDS22 homolog, [Score=87.0, Expect=2e-18]} {Smed: dd_Smed_v6_9362_0_1, dd_Smed_v6_9362_0_1, [RH, Score=405, Expect=5e-131]} {RNA1509_3553} {RNA1310_6024.1, RNA1509_3553} {RNA1509_3553, RNA815_2429}

Mlig455_031049 {REF} {Length: 3115} {Pfam: Leucine rich repeat [PF13855.8, score=92.1]; Leucine Rich repeats (2 copies) [PF12799.9, score=86.2]; Leucine-rich repeat [PF14580.8, score=60.1]; Leucine Rich repeat [PF13516.8, score=24.3]; Guanylate kinase [PF00625.23, score=23.6]; Leucine Rich Repeat [PF00560.35, score=21.3]} {Human: ENSG00000155530, LRGUK, leucine rich repeats and guanylate kinase domain containing, [Score=281, Expect=3e-85]} {Mouse: ENSMUSG00000056215, Lrguk, leucine-rich repeats and guanylate kinase domain containing, [Score=276, Expect=7e-84]} {Dmel: FBgn0028992, sds22, [Score=71.2, Expect=3e-13]} {Celegans: WBGene00011637, sds-22, Protein phosphatase 1 regulatory subunit SDS22 homolog, [Score=91.3, Expect=4e-20]} {Smed: dd_Smed_v6_9362_0_1, dd_Smed_v6_9362_0_1, [Score=259, Expect=2e-78]} {RNA1509_3553} {RNA1310_6024.2} {RNA815_2429}

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