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Results for MligTC455_27783

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_27783 1484 30.92 Mlig455_035810

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.770/0.04450
Region-enriched R6: 1.740/0.02899

PAK1 Mlig455_035810 {REF} {Length: 4597} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=236.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=161.7]; P21-Rho-binding domain [PF00786.30, score=38.5]; ABC1 atypical kinase-like domain [PF03109.18, score=25.7]; Kinase-like [PF14531.8, score=23.7]; Fungal protein kinase [PF17667.3, score=22.8]; Phosphotransferase enzyme family [PF01636.25, score=20.2]} {Human: ENSG00000149269, PAK1, p21 (RAC1) activated kinase 1, [Score=335, Expect=3e-107]; ENSG00000180370, PAK2, p21 (RAC1) activated kinase 2, [Score=335, Expect=1e-107]; ENSG00000077264, PAK3, p21 (RAC1) activated kinase 3, [Score=333, Expect=2e-106]} {Mouse: ENSMUSG00000030774, Pak1, p21 (RAC1) activated kinase 1, [Score=335, Expect=2e-107]; ENSMUSG00000022781, Pak2, p21 (RAC1) activated kinase 2, [Score=334, Expect=2e-107]; ENSMUSG00000031284, Pak3, p21 (RAC1) activated kinase 3, [Score=333, Expect=1e-106]} {Dmel: FBgn0267698, Pak, p21-activated kinase, [Score=336, Expect=7e-105]} {Celegans: WBGene00003144, max-2, Serine/threonine-protein kinase max-2, [Score=325, Expect=3e-105]} {Smed: dd_Smed_v6_1765_0_1, dd_Smed_v6_1765_0_1, [RH, Score=367, Expect=2e-121]} {RNA1509_14484, RNA1509_18868, RNA1509_31969, RNA1509_33044, RNA1509_33197, RNA1509_4715, RNA1509_56367} {RNA1310_5360.1, RNA1509_14484, RNA1509_18868, RNA1509_31969, RNA1509_33044, RNA1509_33197, RNA1509_4715, RNA1509_56367} {RNA1509_14484, RNA1509_18868, RNA1509_31969, RNA1509_33044, RNA1509_33197, RNA1509_4715, RNA1509_56367, RNA815_4593}

Cumulative graph for MligTC455_27783

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -8.594 5.125 0.00056 0.07779
RegionR2 1.77 5.125 0.00283 0.04450
RegionR3 0.994 5.125 0.14239 0.64282
RegionR4 0.534 5.125 0.52170 0.84649
RegionR5 1.388 5.125 0.00973 0.05662
RegionR6 1.74 5.125 0.00064 0.02899
RegionR7 1.383 5.125 0.03616 0.36246
RegionR8 0.785 5.125 0.38840 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 8.038 5.125 0.01211 0.47182
RegenerationR2 0.379 5.125 0.22890 0.67668
RegenerationR3 0.873 5.125 0.01380 0.21551
RegenerationR4 0.553 5.125 0.12749 0.54203
RegenerationR5 0.246 5.125 0.44451 0.82742
RegenerationR6 0.332 5.125 0.32541 0.67137
RegenerationBL 1.009 5.125 0.00475 0.06339
RegenerationTP 0.633 5.125 0.13910 0.55683


Genes with expression patterns similar to MligTC455_27783

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_27783 1484 30.92 Mlig455_035810

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.770/0.04450
Region-enriched R6: 1.740/0.02899

PAK1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_035810 {REF} {Length: 4597} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=236.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=161.7]; P21-Rho-binding domain [PF00786.30, score=38.5]; ABC1 atypical kinase-like domain [PF03109.18, score=25.7]; Kinase-like [PF14531.8, score=23.7]; Fungal protein kinase [PF17667.3, score=22.8]; Phosphotransferase enzyme family [PF01636.25, score=20.2]} {Human: ENSG00000149269, PAK1, p21 (RAC1) activated kinase 1, [Score=335, Expect=3e-107]; ENSG00000180370, PAK2, p21 (RAC1) activated kinase 2, [Score=335, Expect=1e-107]; ENSG00000077264, PAK3, p21 (RAC1) activated kinase 3, [Score=333, Expect=2e-106]} {Mouse: ENSMUSG00000030774, Pak1, p21 (RAC1) activated kinase 1, [Score=335, Expect=2e-107]; ENSMUSG00000022781, Pak2, p21 (RAC1) activated kinase 2, [Score=334, Expect=2e-107]; ENSMUSG00000031284, Pak3, p21 (RAC1) activated kinase 3, [Score=333, Expect=1e-106]} {Dmel: FBgn0267698, Pak, p21-activated kinase, [Score=336, Expect=7e-105]} {Celegans: WBGene00003144, max-2, Serine/threonine-protein kinase max-2, [Score=325, Expect=3e-105]} {Smed: dd_Smed_v6_1765_0_1, dd_Smed_v6_1765_0_1, [RH, Score=367, Expect=2e-121]} {RNA1509_14484, RNA1509_18868, RNA1509_31969, RNA1509_33044, RNA1509_33197, RNA1509_4715, RNA1509_56367} {RNA1310_5360.1, RNA1509_14484, RNA1509_18868, RNA1509_31969, RNA1509_33044, RNA1509_33197, RNA1509_4715, RNA1509_56367} {RNA1509_14484, RNA1509_18868, RNA1509_31969, RNA1509_33044, RNA1509_33197, RNA1509_4715, RNA1509_56367, RNA815_4593}
2. MligTC455_41549 1912 39.84 Mlig455_018620

Neo: -

Age: Down-Up-Down

2.628 0.735 - - 0.935 0.958 - Mlig455_018620 {REF} {Length: 1355} {RNA1509_11971} {RNA1310_12238} {RNA815_7772}
3. MligTC455_22201 892 18.59 Mlig455_045089

Neo: -

Age: -

Region-enriched R7: 1.426/0.02956

Regeneration-upregulated BL: 1.589

Regeneration-enriched BL: 1.589

TLL1 1.822 - - - 0.955 0.867 - Mlig455_045089 {REF} {Length: 3960} {Pfam: CUB domain [PF00431.22, score=500.8]; Astacin (Peptidase family M12A) [PF01400.26, score=226.0]; Coagulation Factor Xa inhibitory site [PF14670.8, score=57.7]; Calcium-binding EGF domain [PF07645.17, score=41.2]; Complement Clr-like EGF-like [PF12662.9, score=32.2]; EGF domain [PF12947.9, score=24.5]; CUB-like domain [PF02408.22, score=24.0]; Human growth factor-like EGF [PF12661.9, score=21.4]; EGF-like domain [PF00008.29, score=20.3]} {Human: ENSG00000038295, TLL1, tolloid like 1, [RH, Score=877, Expect=0.0]; ENSG00000095587, TLL2, tolloid like 2, [RH, Score=876, Expect=0.0]; ENSG00000168487, BMP1, bone morphogenetic protein 1, [RH, Score=865, Expect=0.0]} {Mouse: ENSMUSG00000025013, Tll2, tolloid-like 2, [RH, Score=881, Expect=0.0]; ENSMUSG00000022098, Bmp1, bone morphogenetic protein 1, [RH, Score=867, Expect=0.0]; ENSMUSG00000053626, Tll1, tolloid-like, [RH, Score=863, Expect=0.0]} {Dmel: FBgn0004885, tok, tolkin, [RH, Score=864, Expect=0.0]} {Celegans: WBGene00003555, nas-39, Zinc metalloproteinase nas-39, [RH, Score=716, Expect=0.0]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [RH, Score=888, Expect=0.0]} {RNA1509_7883} {RNA1310_2749, RNA1509_7883} {RNA1509_7883, RNA815_1455}
4. MligTC455_27286 330 6.88 Mlig455_017318

Neo: -

Age: -

0.966 - - - 0.966 - - Mlig455_017318 {REF} {Length: 2873} {RNA1509_26378} {RNA1310_61.2} {RNA815_11919}
5. MligTC455_43550 1501 31.28 Mlig455_065262

Neo: -

Age: -

SSBP3 0.956 - - - 0.956 - - Mlig455_065262 {REF} {Length: 4032} {Human: ENSG00000157216, SSBP3, single stranded DNA binding protein 3, [RH, Score=186, Expect=1e-54]; ENSG00000145687, SSBP2, single stranded DNA binding protein 2, [RH, Score=185, Expect=1e-54]} {Mouse: ENSMUSG00000061887, Ssbp3, single-stranded DNA binding protein 3, [RH, Score=186, Expect=1e-54]; ENSMUSG00000003992, Ssbp2, single-stranded DNA binding protein 2, [RH, Score=185, Expect=8e-55]} {Dmel: FBgn0011481, Ssdp, Sequence-specific single-stranded DNA-binding protein, [RH, Score=192, Expect=2e-56]} {Celegans: WBGene00012990, sam-10, Single-stranded DNA-binding protein homolog sam-10, [RH, Score=91.3, Expect=6e-20]} {Smed: dd_Smed_v6_3876_0_1, dd_Smed_v6_3876_0_1, [RH, Score=178, Expect=2e-51]} {RNA1509_12630, RNA1509_17189, RNA1509_19453, RNA1509_29837, RNA1509_36215, RNA1509_39481, RNA1509_51894, RNA1509_55152} {RNA1310_27347, RNA1509_12630, RNA1509_17189, RNA1509_19453, RNA1509_29837, RNA1509_36215, RNA1509_39481, RNA1509_51894, RNA1509_55152} {RNA1509_12630, RNA1509_17189, RNA1509_19453, RNA1509_29837, RNA1509_36215, RNA1509_39481, RNA1509_51894, RNA1509_55152, RNA815_18789}
6. MligTC455_35049 1260 26.25 Mlig455_033678, Mlig455_050141

Neo: Irradiation

Age: logFC(26M/2M)=0.277

Region-enriched R5: 1.083/0.00294

DENND5B 0.95 - - 0.950 - - -

Mlig455_033678 {REF} {Length: 5690} {TRANSSPLICED} {Pfam: DENN (AEX-3) domain [PF02141.23, score=148.0]; RUN domain [PF02759.21, score=117.5]; PLAT/LH2 domain [PF01477.25, score=45.5]; uDENN domain [PF03456.20, score=44.5]; dDENN domain [PF03455.21, score=43.9]} {Human: ENSG00000170456, DENND5B, DENN domain containing 5B, [Score=370, Expect=2e-106]; ENSG00000184014, DENND5A, DENN domain containing 5A, [Score=362, Expect=1e-103]} {Mouse: ENSMUSG00000035901, Dennd5a, DENN/MADD domain containing 5A, [RH, Score=364, Expect=2e-104]} {Dmel: FBgn0035229, pns, pinstripe, [RH, Score=468, Expect=5e-140]} {Celegans: WBGene00016889, lst-6, Lateral Signaling Target, [RH, Score=274, Expect=2e-74]} {Smed: dd_Smed_v6_7039_0_1, dd_Smed_v6_7039_0_1, [RH, Score=581, Expect=0.0]} {RNA1509_10037} {RNA1310_2524.1, RNA1509_10037} {RNA1509_10037, RNA815_826.1}

Mlig455_050141 {REF} {Length: 5827} {TRANSSPLICED} {Pfam: DENN (AEX-3) domain [PF02141.23, score=148.7]; RUN domain [PF02759.21, score=118.1]; PLAT/LH2 domain [PF01477.25, score=45.5]; uDENN domain [PF03456.20, score=44.4]; dDENN domain [PF03455.21, score=43.8]} {Human: ENSG00000170456, DENND5B, DENN domain containing 5B, [Score=370, Expect=5e-106]; ENSG00000184014, DENND5A, DENN domain containing 5A, [Score=362, Expect=3e-103]} {Mouse: ENSMUSG00000030313, Dennd5b, DENN/MADD domain containing 5B, [Score=379, Expect=9e-110]; ENSMUSG00000035901, Dennd5a, DENN/MADD domain containing 5A, [Score=363, Expect=3e-104]} {Dmel: FBgn0035229, pns, pinstripe, [RH, Score=472, Expect=2e-141]} {Celegans: WBGene00016889, lst-6, Lateral Signaling Target, [RH, Score=274, Expect=1e-74]} {Smed: dd_Smed_v6_7039_0_1, dd_Smed_v6_7039_0_1, [RH, Score=511, Expect=2e-160]} {RNA1509_10037} {RNA1310_2455.1} {RNA815_826.1}

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