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Results for MligTC455_22201

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_22201 892 18.59 Mlig455_045089

Neo: -

Age: -

Region-enriched R7: 1.426/0.02956

Regeneration-upregulated BL: 1.589

Regeneration-enriched BL: 1.589

TLL1 Mlig455_045089 {REF} {Length: 3960} {Pfam: CUB domain [PF00431.22, score=500.8]; Astacin (Peptidase family M12A) [PF01400.26, score=226.0]; Coagulation Factor Xa inhibitory site [PF14670.8, score=57.7]; Calcium-binding EGF domain [PF07645.17, score=41.2]; Complement Clr-like EGF-like [PF12662.9, score=32.2]; EGF domain [PF12947.9, score=24.5]; CUB-like domain [PF02408.22, score=24.0]; Human growth factor-like EGF [PF12661.9, score=21.4]; EGF-like domain [PF00008.29, score=20.3]} {Human: ENSG00000038295, TLL1, tolloid like 1, [RH, Score=877, Expect=0.0]; ENSG00000095587, TLL2, tolloid like 2, [RH, Score=876, Expect=0.0]; ENSG00000168487, BMP1, bone morphogenetic protein 1, [RH, Score=865, Expect=0.0]} {Mouse: ENSMUSG00000025013, Tll2, tolloid-like 2, [RH, Score=881, Expect=0.0]; ENSMUSG00000022098, Bmp1, bone morphogenetic protein 1, [RH, Score=867, Expect=0.0]; ENSMUSG00000053626, Tll1, tolloid-like, [RH, Score=863, Expect=0.0]} {Dmel: FBgn0004885, tok, tolkin, [RH, Score=864, Expect=0.0]} {Celegans: WBGene00003555, nas-39, Zinc metalloproteinase nas-39, [RH, Score=716, Expect=0.0]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [RH, Score=888, Expect=0.0]} {RNA1509_7883} {RNA1310_2749, RNA1509_7883} {RNA1509_7883, RNA815_1455}

Cumulative graph for MligTC455_22201

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.885 4.447 0.41141 1.00000
RegionR2 1.03 4.447 0.01908 0.14864
RegionR3 0.93 4.447 0.00836 0.13557
RegionR4 -0.605 4.447 0.15070 0.40090
RegionR5 -1.351 4.447 0.00100 0.01015
RegionR6 -0.005 4.447 0.99366 1.00000
RegionR7 1.426 4.447 0.00079 0.02956
RegionR8 -0.54 4.447 0.46462 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -6.927 4.447 0.10533 0.82700
RegenerationR2 0.14 4.447 0.68467 0.95061
RegenerationR3 -0.005 4.447 0.98641 1.00000
RegenerationR4 0.65 4.447 0.10323 0.49619
RegenerationR5 1.338 4.447 0.00106 0.05424
RegenerationR6 1.281 4.447 0.00122 0.03855
RegenerationBL 1.589 4.447 0.00011 0.00493 Specific for BL: 1.589
RegenerationTP -0.373 4.447 0.52844 0.91920


Genes with expression patterns similar to MligTC455_22201

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_22201 892 18.59 Mlig455_045089

Neo: -

Age: -

Region-enriched R7: 1.426/0.02956

Regeneration-upregulated BL: 1.589

Regeneration-enriched BL: 1.589

TLL1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_045089 {REF} {Length: 3960} {Pfam: CUB domain [PF00431.22, score=500.8]; Astacin (Peptidase family M12A) [PF01400.26, score=226.0]; Coagulation Factor Xa inhibitory site [PF14670.8, score=57.7]; Calcium-binding EGF domain [PF07645.17, score=41.2]; Complement Clr-like EGF-like [PF12662.9, score=32.2]; EGF domain [PF12947.9, score=24.5]; CUB-like domain [PF02408.22, score=24.0]; Human growth factor-like EGF [PF12661.9, score=21.4]; EGF-like domain [PF00008.29, score=20.3]} {Human: ENSG00000038295, TLL1, tolloid like 1, [RH, Score=877, Expect=0.0]; ENSG00000095587, TLL2, tolloid like 2, [RH, Score=876, Expect=0.0]; ENSG00000168487, BMP1, bone morphogenetic protein 1, [RH, Score=865, Expect=0.0]} {Mouse: ENSMUSG00000025013, Tll2, tolloid-like 2, [RH, Score=881, Expect=0.0]; ENSMUSG00000022098, Bmp1, bone morphogenetic protein 1, [RH, Score=867, Expect=0.0]; ENSMUSG00000053626, Tll1, tolloid-like, [RH, Score=863, Expect=0.0]} {Dmel: FBgn0004885, tok, tolkin, [RH, Score=864, Expect=0.0]} {Celegans: WBGene00003555, nas-39, Zinc metalloproteinase nas-39, [RH, Score=716, Expect=0.0]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [RH, Score=888, Expect=0.0]} {RNA1509_7883} {RNA1310_2749, RNA1509_7883} {RNA1509_7883, RNA815_1455}
2. MligTC455_30909 3582 74.63 Mlig455_043858

Neo: -

Age: -

RBMS2 2.567 - - - 0.954 0.888 0.725 Mlig455_043858 {REF} {Length: 4160} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=55.7]} {Human: ENSG00000076067, RBMS2, RNA binding motif single stranded interacting protein 2, [RH, Score=120, Expect=2e-28]; ENSG00000144642, RBMS3, RNA binding motif single stranded interacting protein 3, [RH, Score=114, Expect=2e-26]} {Mouse: ENSMUSG00000040043, Rbms2, RNA binding motif, single stranded interacting protein 2, [RH, Score=120, Expect=5e-29]; ENSMUSG00000026970, Rbms1, RNA binding motif, single stranded interacting protein 1, [RH, Score=114, Expect=1e-26]} {Dmel: FBgn0052423, shep, alan shepard, [RH, Score=105, Expect=2e-23]} {Celegans: WBGene00006331, sup-26, SUPpressor, [Score=111, Expect=8e-27]} {Smed: dd_Smed_v6_2612_0_2, dd_Smed_v6_2612_0_2, [RH, Score=111, Expect=4e-25]} {RNA1509_833} {RNA1310_2595.1} {RNA815_5711}
3. MligTC455_27783 1484 30.92 Mlig455_035810

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.770/0.04450
Region-enriched R6: 1.740/0.02899

PAK1 1.822 - - - 0.955 0.867 - Mlig455_035810 {REF} {Length: 4597} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=236.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=161.7]; P21-Rho-binding domain [PF00786.30, score=38.5]; ABC1 atypical kinase-like domain [PF03109.18, score=25.7]; Kinase-like [PF14531.8, score=23.7]; Fungal protein kinase [PF17667.3, score=22.8]; Phosphotransferase enzyme family [PF01636.25, score=20.2]} {Human: ENSG00000149269, PAK1, p21 (RAC1) activated kinase 1, [Score=335, Expect=3e-107]; ENSG00000180370, PAK2, p21 (RAC1) activated kinase 2, [Score=335, Expect=1e-107]; ENSG00000077264, PAK3, p21 (RAC1) activated kinase 3, [Score=333, Expect=2e-106]} {Mouse: ENSMUSG00000030774, Pak1, p21 (RAC1) activated kinase 1, [Score=335, Expect=2e-107]; ENSMUSG00000022781, Pak2, p21 (RAC1) activated kinase 2, [Score=334, Expect=2e-107]; ENSMUSG00000031284, Pak3, p21 (RAC1) activated kinase 3, [Score=333, Expect=1e-106]} {Dmel: FBgn0267698, Pak, p21-activated kinase, [Score=336, Expect=7e-105]} {Celegans: WBGene00003144, max-2, Serine/threonine-protein kinase max-2, [Score=325, Expect=3e-105]} {Smed: dd_Smed_v6_1765_0_1, dd_Smed_v6_1765_0_1, [RH, Score=367, Expect=2e-121]} {RNA1509_14484, RNA1509_18868, RNA1509_31969, RNA1509_33044, RNA1509_33197, RNA1509_4715, RNA1509_56367} {RNA1310_5360.1, RNA1509_14484, RNA1509_18868, RNA1509_31969, RNA1509_33044, RNA1509_33197, RNA1509_4715, RNA1509_56367} {RNA1509_14484, RNA1509_18868, RNA1509_31969, RNA1509_33044, RNA1509_33197, RNA1509_4715, RNA1509_56367, RNA815_4593}
4. MligTC455_46007 1095 22.82 Mlig455_015551

Neo: -

Age: -

Regeneration-upregulated BL: 1.762

Regeneration-enriched BL: 1.762

RBMS3 1.82 - - - 0.861 - 0.959 Mlig455_015551 {REF} {Length: 2417} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=48.0]} {Human: ENSG00000144642, RBMS3, RNA binding motif single stranded interacting protein 3, [RH, Score=114, Expect=3e-27]; ENSG00000153250, RBMS1, RNA binding motif single stranded interacting protein 1, [RH, Score=112, Expect=1e-26]} {Mouse: ENSMUSG00000026970, Rbms1, RNA binding motif, single stranded interacting protein 1, [RH, Score=115, Expect=8e-28]; ENSMUSG00000039607, Rbms3, RNA binding motif, single stranded interacting protein, [RH, Score=113, Expect=5e-27]} {Dmel: FBgn0052423, shep, alan shepard, [Score=100, Expect=4e-22]} {Celegans: WBGene00006331, sup-26, SUPpressor, [RH, Score=118, Expect=9e-29]} {Smed: dd_Smed_v6_2612_0_1, dd_Smed_v6_2612_0_1, [RH, Score=109, Expect=2e-25]} {RNA1509_18229} {RNA1310_2231} {RNA815_12809}
5. MligTC455_15942 908 18.92 Mlig455_035020, Mlig455_053446

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.273

NR1I2 1.815 - - - 0.848 0.967 -

Mlig455_035020 {REF} {Length: 4424} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=73.8]} {Human: ENSG00000144852, NR1I2, nuclear receptor subfamily 1 group I member 2, [Score=87.4, Expect=1e-17]} {Mouse: ENSMUSG00000022809, Nr1i2, nuclear receptor subfamily 1, group I, member 2, [Score=84.3, Expect=6e-17]; ENSMUSG00000022479, Vdr, vitamin D (1,25-dihydroxyvitamin D3) receptor, [Score=81.3, Expect=6e-16]} {Dmel: FBgn0003720, tll, tailless, [Score=82.0, Expect=3e-16]} {Celegans: WBGene00000908, daf-12, Nuclear hormone receptor family member daf-12, [Score=99.4, Expect=2e-21]} {Smed: dd_Smed_v6_5200_0_1, dd_Smed_v6_5200_0_1, [Score=91.3, Expect=3e-19]} {RNA1509_8358} {RNA1310_9876} {RNA815_22592}

Mlig455_053446 {REF} {Length: 4372} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=73.7]} {Human: ENSG00000144852, NR1I2, nuclear receptor subfamily 1 group I member 2, [Score=87.0, Expect=2e-17]} {Mouse: ENSMUSG00000022809, Nr1i2, nuclear receptor subfamily 1, group I, member 2, [Score=84.0, Expect=9e-17]; ENSMUSG00000022479, Vdr, vitamin D (1,25-dihydroxyvitamin D3) receptor, [Score=80.9, Expect=8e-16]; ENSMUSG00000002393, Nr2f6, nuclear receptor subfamily 2, group F, member 6, [Score=80.1, Expect=1e-15]} {Dmel: FBgn0003720, tll, tailless, [Score=82.4, Expect=3e-16]} {Celegans: WBGene00000908, daf-12, Nuclear hormone receptor family member daf-12, [Score=99.8, Expect=1e-21]} {Smed: dd_Smed_v6_5200_0_1, dd_Smed_v6_5200_0_1, [Score=91.3, Expect=2e-19]} {RNA1509_8358} {RNA1310_9876} {RNA815_22592}
6. MligTC455_34166 2039 42.49 Mlig455_044798, Mlig455_055561

Neo: -

Age: logFC(26M/2M)=1.818

Region-enriched R8: 1.448/0.03435

MYH6 1.802 - - - 0.958 0.844 -

Mlig455_044798 {REF} {Length: 8009} {Pfam: Myosin head (motor domain) [PF00063.23, score=936.1]; Myosin tail [PF01576.21, score=581.5]; Myosin N-terminal SH3-like domain [PF02736.21, score=58.5]; Protein of unknown function (DUF1664) [PF07889.14, score=41.0]; Crescentin protein [PF19220.2, score=36.6]} {Human: ENSG00000197616, MYH6, myosin heavy chain 6, [RH, Score=2093, Expect=0.0]; ENSG00000092054, MYH7, myosin heavy chain 7, [RH, Score=2086, Expect=0.0]; ENSG00000109061, MYH1, myosin heavy chain 1, [RH, Score=2044, Expect=0.0]; ENSG00000125414, MYH2, myosin heavy chain 2, [RH, Score=2044, Expect=0.0]; ENSG00000133020, MYH8, myosin heavy chain 8, [RH, Score=2035, Expect=0.0]; ENSG00000264424, MYH4, myosin heavy chain 4, [RH, Score=2033, Expect=0.0]; ENSG00000109063, MYH3, myosin heavy chain 3, [RH, Score=1994, Expect=0.0]} {Mouse: ENSMUSG00000040752, Myh6, myosin, heavy polypeptide 6, cardiac muscle, alpha, [RH, Score=2089, Expect=0.0]; ENSMUSG00000053093, Myh7, myosin, heavy polypeptide 7, cardiac muscle, beta, [RH, Score=2084, Expect=0.0]; ENSMUSG00000057003, Myh4, myosin, heavy polypeptide 4, skeletal muscle, [RH, Score=2081, Expect=0.0]; ENSMUSG00000056328, Myh1, myosin, heavy polypeptide 1, skeletal muscle, adult, [RH, Score=2056, Expect=0.0]; ENSMUSG00000033196, Myh2, myosin, heavy polypeptide 2, skeletal muscle, adult, [RH, Score=2053, Expect=0.0]; ENSMUSG00000055775, Myh8, myosin, heavy polypeptide 8, skeletal muscle, perinatal, [RH, Score=2042, Expect=0.0]; ENSMUSG00000060180, Myh13, myosin, heavy polypeptide 13, skeletal muscle, [RH, Score=2001, Expect=0.0]; ENSMUSG00000020908, Myh3, myosin, heavy polypeptide 3, skeletal muscle, embryonic, [RH, Score=2001, Expect=0.0]} {Dmel: FBgn0264695, Mhc, Myosin heavy chain, [RH, Score=2114, Expect=0.0]} {Celegans: WBGene00019064, myo-5, MYOsin heavy chain structural genes, [RH, Score=1969, Expect=0.0]} {Smed: dd_Smed_v6_579_0_1, dd_Smed_v6_579_0_1, [RH, Score=2701, Expect=0.0]} {RNA1509_4871} {RNA1310_412.1} {RNA815_129.1}

Mlig455_055561 {REF} {Length: 6745} {Pfam: Myosin head (motor domain) [PF00063.23, score=936.1]; Myosin tail [PF01576.21, score=581.5]; Myosin N-terminal SH3-like domain [PF02736.21, score=58.5]; Protein of unknown function (DUF1664) [PF07889.14, score=40.5]; Crescentin protein [PF19220.2, score=36.5]} {Human: ENSG00000197616, MYH6, myosin heavy chain 6, [RH, Score=2093, Expect=0.0]; ENSG00000092054, MYH7, myosin heavy chain 7, [RH, Score=2086, Expect=0.0]; ENSG00000109061, MYH1, myosin heavy chain 1, [RH, Score=2045, Expect=0.0]; ENSG00000125414, MYH2, myosin heavy chain 2, [RH, Score=2045, Expect=0.0]; ENSG00000133020, MYH8, myosin heavy chain 8, [RH, Score=2035, Expect=0.0]; ENSG00000264424, MYH4, myosin heavy chain 4, [RH, Score=2033, Expect=0.0]; ENSG00000109063, MYH3, myosin heavy chain 3, [RH, Score=1993, Expect=0.0]} {Mouse: ENSMUSG00000040752, Myh6, myosin, heavy polypeptide 6, cardiac muscle, alpha, [RH, Score=2092, Expect=0.0]; ENSMUSG00000053093, Myh7, myosin, heavy polypeptide 7, cardiac muscle, beta, [RH, Score=2083, Expect=0.0]; ENSMUSG00000057003, Myh4, myosin, heavy polypeptide 4, skeletal muscle, [RH, Score=2080, Expect=0.0]; ENSMUSG00000056328, Myh1, myosin, heavy polypeptide 1, skeletal muscle, adult, [RH, Score=2056, Expect=0.0]; ENSMUSG00000033196, Myh2, myosin, heavy polypeptide 2, skeletal muscle, adult, [RH, Score=2051, Expect=0.0]; ENSMUSG00000055775, Myh8, myosin, heavy polypeptide 8, skeletal muscle, perinatal, [RH, Score=2041, Expect=0.0]; ENSMUSG00000060180, Myh13, myosin, heavy polypeptide 13, skeletal muscle, [RH, Score=2001, Expect=0.0]; ENSMUSG00000020908, Myh3, myosin, heavy polypeptide 3, skeletal muscle, embryonic, [RH, Score=2000, Expect=0.0]} {Dmel: FBgn0264695, Mhc, Myosin heavy chain, [RH, Score=2114, Expect=0.0]} {Celegans: WBGene00019064, myo-5, MYOsin heavy chain structural genes, [RH, Score=1969, Expect=0.0]} {Smed: dd_Smed_v6_579_0_1, dd_Smed_v6_579_0_1, [RH, Score=2701, Expect=0.0]} {RNA1509_4871} {RNA1310_412.1} {RNA815_129.1}
7. MligTC455_45997 80 1.68 Mlig455_004065

Neo: -

Age: -

GNAO1 1.733 - - - - 0.755 0.978 Mlig455_004065 {REF} {Length: 3691} {Pfam: G-protein alpha subunit [PF00503.22, score=408.5]; ADP-ribosylation factor family [PF00025.23, score=62.4]; Gtr1/RagA G protein conserved region [PF04670.14, score=24.2]} {Human: ENSG00000087258, GNAO1, G protein subunit alpha o1, [RH, Score=617, Expect=0.0]} {Mouse: ENSMUSG00000031748, Gnao1, guanine nucleotide binding protein, alpha O, [RH, Score=614, Expect=0.0]} {Dmel: FBgn0001122, Galphao, G protein alpha o subunit, [RH, Score=649, Expect=0.0]} {Celegans: WBGene00001648, goa-1, Guanine nucleotide-binding protein G(o) subunit alpha, [RH, Score=643, Expect=0.0]} {Smed: dd_Smed_v6_1656_0_1, dd_Smed_v6_1656_0_1, [RH, Score=674, Expect=0.0]} {RNA1509_25755, RNA1509_7653} {RNA1310_5003, RNA1509_25755} {RNA1509_25755, RNA815_2342}
8. MligTC455_52377 541 11.26 Mlig455_069932, Mlig455_069939

Neo: Int S/G2/M

Age: -

1.731 - - - - 0.774 0.957

Mlig455_069932 {REF} {Length: 1671} {TRANSSPLICED} {RNA1509_41731} {RNA1310_28989} {RNA815_37154}

Mlig455_069939 {REF} {Length: 1669} {TRANSSPLICED} {RNA1509_41731} {RNA1310_28989, RNA1509_41731} {RNA1509_41731, RNA815_37154}
9. MligTC455_46006 1171 24.39 Mlig455_003506

Neo: -

Age: logFC(26M/2M)=-0.356

Regeneration-upregulated BL: 1.838

Regeneration-enriched BL: 1.838

RBMS3 1.718 - - - 0.762 - 0.956 Mlig455_003506 {REF} {Length: 4692} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=48.0]} {Human: ENSG00000144642, RBMS3, RNA binding motif single stranded interacting protein 3, [RH, Score=114, Expect=3e-27]; ENSG00000153250, RBMS1, RNA binding motif single stranded interacting protein 1, [RH, Score=112, Expect=1e-26]} {Mouse: ENSMUSG00000026970, Rbms1, RNA binding motif, single stranded interacting protein 1, [RH, Score=115, Expect=8e-28]; ENSMUSG00000039607, Rbms3, RNA binding motif, single stranded interacting protein, [RH, Score=113, Expect=5e-27]} {Dmel: FBgn0052423, shep, alan shepard, [Score=100, Expect=4e-22]} {Celegans: WBGene00006331, sup-26, SUPpressor, [RH, Score=118, Expect=9e-29]} {Smed: dd_Smed_v6_2612_0_1, dd_Smed_v6_2612_0_1, [RH, Score=109, Expect=2e-25]} {RNA1509_11819, RNA1509_18229, RNA1509_24197, RNA1509_30966, RNA1509_34693} {RNA1310_2231, RNA1509_11819, RNA1509_18229, RNA1509_24197, RNA1509_30966, RNA1509_34693} {RNA1509_11819, RNA1509_18229, RNA1509_24197, RNA1509_30966, RNA1509_34693, RNA815_12809}
10. MligTC455_33016 46 0.96 Mlig455_030897

Neo: -

Age: -

UTP20 1.702 - - - - 0.745 0.957 Mlig455_030897 {REF} {Length: 9860} {TRANSSPLICED} {Pfam: Down-regulated in metastasis [PF07539.14, score=169.0]} {Human: ENSG00000120800, UTP20, UTP20, small subunit processome component, [Score=269, Expect=3e-71]} {Mouse: ENSMUSG00000004356, Utp20, UTP20 small subunit processome component, [RH, Score=271, Expect=3e-72]} {Dmel: FBgn0034734, CG4554, [RH, Score=181, Expect=6e-45]} {Celegans: WBGene00007050, utp-20, UTP small subunit (SSU) processome component homolog, [RH, Score=167, Expect=7e-41]} {Smed: dd_Smed_v6_5777_0_1, dd_Smed_v6_5777_0_1, [Score=130, Expect=1e-29]} {RNA1509_30314} {RNA1310_332, RNA1509_30314} {RNA1509_30314, RNA815_127.1}
11. MligTC455_39569 194 4.05 Mlig455_006055, Mlig455_028715

Neo: Int S/G2/M

Age: -

ZAN 0.984 - - - - - 0.984

Mlig455_006055 {REF} {Length: 1262} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=61.5]} {RNA1310_85984}

Mlig455_028715 {REF} {Length: 4529} {Pfam: SH2 domain [PF00017.26, score=22.0]} {Human: ENSG00000146839, ZAN, zonadhesin (gene/pseudogene), [Score=60.1, Expect=2e-08]} {RNA1509_15981} {RNA1310_15741} {RNA815_13643}
12. MligTC455_12236 60 1.26 Mlig455_048744

Neo: -

Age: -

0.97 - - - - - 0.970 Mlig455_048744 {REF} {Length: 785} {NoTransDecoderORF} {RNA1509_30946} {RNA1310_87811} {RNA815_14080}
13. MligTC455_26512 128 2.67 Mlig455_069089

Neo: -

Age: Up-Down-Down

PRKDC 0.97 - - - - - 0.970 Mlig455_069089 {REF} {Length: 15905} {Pfam: NUC194 domain [PF08163.14, score=230.9]; DNA-PKcs, CC5 [PF19704.1, score=218.9]; Phosphatidylinositol 3- and 4-kinase [PF00454.29, score=139.7]; FAT domain [PF02259.25, score=33.6]; FATC domain [PF02260.22, score=27.0]; DDE superfamily endonuclease [PF13358.8, score=24.7]; Helix-turn-helix domain [PF13518.8, score=22.8]} {Human: ENSG00000253729, PRKDC, protein kinase, DNA-activated, catalytic subunit, [Score=652, Expect=0.0]} {Mouse: ENSMUSG00000022672, Prkdc, protein kinase, DNA activated, catalytic polypeptide, [Score=624, Expect=1e-178]} {Dmel: FBgn0021796, Tor, Target of rapamycin, [Score=152, Expect=8e-36]} {Celegans: WBGene00002583, let-363, Target of rapamycin homolog, [Score=149, Expect=3e-35]} {Smed: dd_Smed_v6_8462_0_2, dd_Smed_v6_8462_0_2, [RH, Score=284, Expect=5e-76]} {RNA1509_11402, RNA1509_47977, RNA1509_60024} {RNA1310_372, RNA1509_47977, RNA1509_60024} {RNA1509_47977, RNA1509_60024, RNA815_3968}
14. MligTC455_41109 212 4.42 Mlig455_044541, Mlig455_068558

Neo: -

Age: Down-Down-Up

0.968 - - - - - 0.968

Mlig455_044541 {REF} {Length: 2618} {RNA1509_50994} {RNA1310_14102} {RNA815_21266}

Mlig455_068558 {REF} {Length: 2571} {RNA1509_50994} {RNA1310_14102} {RNA815_21266}
15. MligTC455_18219 159 3.31 Mlig455_030558

Neo: -

Age: logFC(26M/2M)=0.671

0.965 - - - - - 0.965 Mlig455_030558 {REF} {Length: 1656} {TRANSSPLICED} {RNA1310_40507.1} {RNA815_32588}
16. MligTC455_36457 455 9.47 Mlig455_041217

Neo: -

Age: -

RNF31 0.964 - - - - - 0.964 Mlig455_041217 {REF} {Length: 4319} {TRANSSPLICED} {Pfam: E3 Ubiquitin Ligase RBR C-terminal domain [PF18091.3, score=39.8]} {Human: ENSG00000285152, RNF31, ring finger protein 31, [Score=100, Expect=5e-21]; ENSG00000092098, RNF31, ring finger protein 31, [Score=100, Expect=5e-21]; ENSG00000259529, AL136295.5, novel transcript, [Score=99.8, Expect=5e-21]; ENSG00000284845, AL136295.10, novel transcript, [Score=99.8, Expect=5e-21]} {Mouse: ENSMUSG00000047098, Rnf31, ring finger protein 31, [Score=98.2, Expect=2e-20]} {Dmel: FBgn0085446, CG34417, [Score=81.6, Expect=4e-15]} {RNA1509_20702} {RNA1310_6690} {RNA815_6553.1}
17. MligTC455_36458 468 9.75 Mlig455_041237

Neo: -

Age: -

RNF31 0.964 - - - - - 0.964 Mlig455_041237 {REF} {Length: 4269} {TRANSSPLICED} {Pfam: E3 Ubiquitin Ligase RBR C-terminal domain [PF18091.3, score=42.5]} {Human: ENSG00000092098, RNF31, ring finger protein 31, [Score=111, Expect=4e-24]; ENSG00000285152, RNF31, ring finger protein 31, [Score=111, Expect=4e-24]; ENSG00000259529, AL136295.5, novel transcript, [Score=109, Expect=4e-24]; ENSG00000284845, AL136295.10, novel transcript, [Score=109, Expect=4e-24]} {Mouse: ENSMUSG00000047098, Rnf31, ring finger protein 31, [Score=112, Expect=9e-25]} {Dmel: FBgn0085446, CG34417, [Score=82.8, Expect=1e-15]} {RNA1509_19319, RNA1509_20702, RNA1509_24854, RNA1509_32163, RNA1509_33237, RNA1509_36618, RNA1509_39561, RNA1509_41517, RNA1509_53033} {RNA1310_6690, RNA1509_19319, RNA1509_20702, RNA1509_24854, RNA1509_32163, RNA1509_33237, RNA1509_36618, RNA1509_39561, RNA1509_41517, RNA1509_53033} {RNA1509_19319, RNA1509_20702, RNA1509_24854, RNA1509_32163, RNA1509_33237, RNA1509_36618, RNA1509_39561, RNA1509_41517, RNA1509_53033, RNA815_6553.1}
18. MligTC455_26123 80 1.67 Mlig455_037016

Neo: -

Age: -

0.962 - - - - - 0.962 Mlig455_037016 {REF} {Length: 2931} {RNA1509_41127} {RNA1310_16094.1} {RNA815_15247.1}
19. MligTC455_51337 178 3.71 Mlig455_037475

Neo: -

Age: -

IARS2 0.962 - - - - - 0.962 Mlig455_037475 {REF} {Length: 3731} {TRANSSPLICED} {Pfam: tRNA synthetases class I (I, L, M and V) [PF00133.24, score=453.9]; tRNA synthetases class I (M) [PF09334.13, score=66.0]; Anticodon-binding domain of tRNA ligase [PF08264.15, score=47.6]; Leucyl-tRNA synthetase, Domain 2 [PF13603.8, score=24.7]} {Human: ENSG00000067704, IARS2, isoleucyl-tRNA synthetase 2, mitochondrial, [RH, Score=553, Expect=0.0]} {Mouse: ENSMUSG00000026618, Iars2, isoleucine-tRNA synthetase 2, mitochondrial, [RH, Score=556, Expect=0.0]} {Dmel: FBgn0036569, IleRS-m, Isoleucyl-tRNA synthetase, mitochondrial, [RH, Score=510, Expect=3e-165]} {Celegans: WBGene00002153, iars-2, Isoleucyl Amino-acyl tRNA Synthetase, [RH, Score=462, Expect=4e-147]} {Smed: dd_Smed_v6_7613_0_1, dd_Smed_v6_7613_0_1, [RH, Score=529, Expect=1e-172]} {RNA1509_14916} {RNA1310_3724, RNA1509_14916} {RNA1509_14916, RNA815_38112}
20. MligTC455_17985 100 2.08 Mlig455_011996

Neo: -

Age: -

0.961 - - - - - 0.961 Mlig455_011996 {REF} {Length: 2094} {TRANSSPLICED} {Pfam: Protein of unknown function (DUF1294) [PF06961.15, score=59.4]} {RNA1509_56809} {RNA1310_44848} {RNA815_48983}
21. MligTC455_28387 46 0.95 Mlig455_027293, Mlig455_060326

Neo: -

Age: -

0.961 - - - 0.961 - -

Mlig455_027293 {REF} {Length: 2294} {NoTransDecoderORF} {RNA1509_13222} {RNA1310_34828.2} {RNA815_11419.1}

Mlig455_060326 {REF} {Length: 364} {NoTransDecoderORF} {RNA1509_28242} {RNA1310_101668} {RNA815_11419.1}
22. MligTC455_41108 96 2.01 Mlig455_002394

Neo: -

Age: -

0.96 - - - - - 0.960 Mlig455_002394 {REF} {Length: 3247} {RNA1509_50994} {RNA1310_9012.2} {RNA815_31617.1}
23. MligTC455_17914 199 4.14 Mlig455_029637

Neo: -

Age: -

AP2M1 0.959 - - - - - 0.959 Mlig455_029637 {REF} {Length: 3242} {TRANSSPLICED} {Pfam: Adaptor complexes medium subunit family [PF00928.23, score=265.9]; Clathrin adaptor complex small chain [PF01217.22, score=24.7]} {Human: ENSG00000161203, AP2M1, adaptor related protein complex 2 subunit mu 1, [RH, Score=754, Expect=0.0]} {Mouse: ENSMUSG00000022841, Ap2m1, adaptor-related protein complex 2, mu 1 subunit, [RH, Score=754, Expect=0.0]} {Dmel: FBgn0263351, AP-2mu, Adaptor Protein complex 2, mu subunit, [RH, Score=750, Expect=0.0]} {Celegans: WBGene00001082, dpy-23, AP-2 complex subunit mu, [RH, Score=723, Expect=0.0]} {Smed: dd_Smed_v6_1271_0_1, dd_Smed_v6_1271_0_1, [RH, Score=732, Expect=0.0]} {RNA1509_24209} {RNA1310_15131.1} {RNA815_3295.1}
24. MligTC455_27288 212 4.42 Mlig455_032046

Neo: -

Age: Down-Up-Down

0.958 - - - 0.958 - - Mlig455_032046 {REF} {Length: 6066} {Smed: dd_Smed_v6_8694_0_1, dd_Smed_v6_8694_0_1, [Score=43.5, Expect=8e-06]} {RNA1509_31401, RNA1509_32396} {RNA1310_3059.1, RNA1509_31401} {RNA1509_31401, RNA815_7477.1}
25. MligTC455_51848 300 6.25 Mlig455_046814

Neo: -

Age: -

0.958 - - - - 0.958 - Mlig455_046814 {REF} {Length: 1471} {Pfam: WIF domain [PF02019.20, score=46.7]} {RNA1509_28045} {RNA1310_21900.2, RNA1509_28045} {RNA1509_28045, RNA815_9756}
26. MligTC455_43550 1501 31.28 Mlig455_065262

Neo: -

Age: -

SSBP3 0.957 - - - 0.957 - - Mlig455_065262 {REF} {Length: 4032} {Human: ENSG00000157216, SSBP3, single stranded DNA binding protein 3, [RH, Score=186, Expect=1e-54]; ENSG00000145687, SSBP2, single stranded DNA binding protein 2, [RH, Score=185, Expect=1e-54]} {Mouse: ENSMUSG00000061887, Ssbp3, single-stranded DNA binding protein 3, [RH, Score=186, Expect=1e-54]; ENSMUSG00000003992, Ssbp2, single-stranded DNA binding protein 2, [RH, Score=185, Expect=8e-55]} {Dmel: FBgn0011481, Ssdp, Sequence-specific single-stranded DNA-binding protein, [RH, Score=192, Expect=2e-56]} {Celegans: WBGene00012990, sam-10, Single-stranded DNA-binding protein homolog sam-10, [RH, Score=91.3, Expect=6e-20]} {Smed: dd_Smed_v6_3876_0_1, dd_Smed_v6_3876_0_1, [RH, Score=178, Expect=2e-51]} {RNA1509_12630, RNA1509_17189, RNA1509_19453, RNA1509_29837, RNA1509_36215, RNA1509_39481, RNA1509_51894, RNA1509_55152} {RNA1310_27347, RNA1509_12630, RNA1509_17189, RNA1509_19453, RNA1509_29837, RNA1509_36215, RNA1509_39481, RNA1509_51894, RNA1509_55152} {RNA1509_12630, RNA1509_17189, RNA1509_19453, RNA1509_29837, RNA1509_36215, RNA1509_39481, RNA1509_51894, RNA1509_55152, RNA815_18789}
27. MligTC455_47139 2009 41.85 Mlig455_044514

Neo: -

Age: logFC(26M/2M)=0.379

HSPA5 0.956 - - - 0.956 - - Mlig455_044514 {REF} {Length: 3227} {TRANSSPLICED} {Pfam: Hsp70 protein [PF00012.22, score=111.5]} {Human: ENSG00000044574, HSPA5, heat shock protein family A (Hsp70) member 5, [Score=197, Expect=1e-57]} {Mouse: ENSMUSG00000026864, Hspa5, heat shock protein 5, [Score=199, Expect=3e-58]} {Dmel: FBgn0001218, Hsc70-3, Heat shock 70-kDa protein cognate 3, [Score=186, Expect=7e-54]} {Celegans: WBGene00002007, hsp-3, Heat shock 70 kDa protein C, [Score=190, Expect=2e-58]} {Smed: dd_Smed_v6_2648_0_1, dd_Smed_v6_2648_0_1, [Score=228, Expect=2e-69]} {RNA1509_14123, RNA1509_23097, RNA1509_25501, RNA1509_31115, RNA1509_37821} {RNA1310_10295, RNA1509_14123, RNA1509_23097, RNA1509_31115, RNA1509_37821} {RNA1509_14123, RNA1509_23097, RNA1509_31115, RNA1509_37821, RNA815_3701}
28. MligTC455_52724 529 11.02 Mlig455_032117

Neo: -

Age: logFC(26M/2M)=-0.559

0.954 - - - - - 0.954 Mlig455_032117 {REF} {Length: 5133} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=57.3]; Capsular polysaccharide synthesis protein [PF05704.14, score=19.1]} {Smed: dd_Smed_v6_6819_0_1, dd_Smed_v6_6819_0_1, [Score=135, Expect=3e-36]} {RNA1509_41314} {RNA1310_23090.1} {RNA815_9794.1}
29. MligTC455_07023 32 0.67 Mlig455_018609

Neo: -

Age: -

TMEM243 0.952 - - - - - 0.952 Mlig455_018609 {REF} {Length: 1106} {TRANSSPLICED} {Pfam: Protein of unknown function (DUF2678) [PF10856.10, score=53.8]} {Human: ENSG00000135185, TMEM243, transmembrane protein 243, [RH, Score=64.7, Expect=5e-13]} {Mouse: ENSMUSG00000079659, Tmem243, transmembrane protein 243, mitochondrial, [Score=49.3, Expect=1e-07]} {RNA1509_52894} {RNA1310_40265} {RNA815_19809}
30. MligTC455_27784 357 7.44 Mlig455_058367

Neo: -

Age: Down-Up-Down

PAK3 0.952 - - - 0.952 - - Mlig455_058367 {REF} {Length: 3790} {Pfam: Protein kinase domain [PF00069.27, score=237.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=162.0]; P21-Rho-binding domain [PF00786.30, score=34.0]; ABC1 atypical kinase-like domain [PF03109.18, score=25.7]; Kinase-like [PF14531.8, score=23.8]; Fungal protein kinase [PF17667.3, score=22.8]; Phosphotransferase enzyme family [PF01636.25, score=20.3]} {Human: ENSG00000077264, PAK3, p21 (RAC1) activated kinase 3, [Score=349, Expect=9e-113]; ENSG00000180370, PAK2, p21 (RAC1) activated kinase 2, [Score=334, Expect=3e-107]; ENSG00000149269, PAK1, p21 (RAC1) activated kinase 1, [Score=332, Expect=3e-106]} {Mouse: ENSMUSG00000022781, Pak2, p21 (RAC1) activated kinase 2, [Score=333, Expect=3e-107]; ENSMUSG00000031284, Pak3, p21 (RAC1) activated kinase 3, [Score=332, Expect=2e-106]; ENSMUSG00000030774, Pak1, p21 (RAC1) activated kinase 1, [Score=332, Expect=2e-106]} {Dmel: FBgn0267698, Pak, p21-activated kinase, [Score=331, Expect=8e-103]} {Celegans: WBGene00003144, max-2, Serine/threonine-protein kinase max-2, [Score=321, Expect=9e-104]} {Smed: dd_Smed_v6_1765_0_1, dd_Smed_v6_1765_0_1, [RH, Score=368, Expect=8e-122]} {RNA1509_4715} {RNA1310_5360.1} {RNA815_4593}
31. MligTC455_34084 1810 37.72 Mlig455_030226

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.335

TTN 0.952 - - - 0.952 - - Mlig455_030226 {REF} {Length: 12171} {Pfam: Fibronectin type III domain [PF00041.23, score=719.8]; Immunoglobulin I-set domain [PF07679.18, score=611.3]; Immunoglobulin domain [PF13927.8, score=350.4]; Protein kinase domain [PF00069.27, score=211.0]; Immunoglobulin domain [PF13895.8, score=193.9]; Immunoglobulin domain [PF00047.27, score=144.8]; Immunoglobulin V-set domain [PF07686.19, score=123.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=109.5]; Purple acid Phosphatase, N-terminal domain [PF16656.7, score=79.6]; Natural killer cell receptor 2B4 [PF11465.10, score=48.7]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=45.0]; Tissue factor [PF01108.19, score=40.1]; Penicillin-Binding Protein C-terminus Family [PF06832.14, score=32.4]; Immunoglobulin C1-set domain [PF07654.17, score=30.9]; ABC1 atypical kinase-like domain [PF03109.18, score=30.5]; Fibronectin type III domain [PF16893.7, score=30.0]; Immunoglobulin domain [PF18452.3, score=21.9]; Bacterial macroglobulin domain 6 [PF17962.3, score=20.5]; Alphaherpesvirus glycoprotein E [PF02480.18, score=19.9]} {Human: ENSG00000155657, TTN, titin, [RH, Score=1193, Expect=0.0]} {Mouse: ENSMUSG00000051747, Ttn, titin, [RH, Score=1201, Expect=0.0]} {Dmel: FBgn0005666, bt, bent, [Score=2269, Expect=0.0]} {Celegans: WBGene00006759, unc-22, Twitchin, [RH, Score=2184, Expect=0.0]} {Smed: dd_Smed_v6_2544_0_1, dd_Smed_v6_2544_0_1, [Score=3410, Expect=0.0]} {RNA1509_25367, RNA1509_33534, RNA1509_577} {RNA1310_35.1, RNA1509_25367, RNA1509_33534, RNA1509_577} {RNA1509_25367, RNA1509_33534, RNA1509_577, RNA815_17}
32. MligTC455_42448 849 17.69 Mlig455_031562

Neo: -

Age: -

0.952 - - - 0.952 - - Mlig455_031562 {REF} {Length: 2282} {RNA1509_30650} {RNA1310_36875.1} {RNA815_12020}
33. MligTC455_22549 36 0.74 Mlig455_057952

Neo: -

Age: -

0.951 - - - - - 0.951 Mlig455_057952 {REF} {Length: 391} {RNA1310_54013.1} {RNA815_47584}
34. MligTC455_36452 280 5.84 Mlig455_035563

Neo: -

Age: Down-Up-Down

FBXW7 0.95 - - - - - 0.950 Mlig455_035563 {REF} {Length: 4662} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=132.2]; F-box-like [PF12937.9, score=49.0]; F-box domain [PF00646.35, score=33.3]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=23.3]; Nucleoporin Nup120/160 [PF11715.10, score=22.7]} {Human: ENSG00000109670, FBXW7, F-box and WD repeat domain containing 7, [RH, Score=429, Expect=8e-143]} {Mouse: ENSMUSG00000028086, Fbxw7, F-box and WD-40 domain protein 7, [RH, Score=429, Expect=1e-142]} {Dmel: FBgn0041171, ago, archipelago, [RH, Score=414, Expect=2e-131]} {Celegans: WBGene00004767, sel-10, F-box/WD repeat-containing protein sel-10, [RH, Score=310, Expect=2e-98]} {Smed: dd_Smed_v6_8211_0_1, dd_Smed_v6_8211_0_1, [RH, Score=282, Expect=2e-89]} {RNA1509_19180, RNA1509_36471} {RNA1310_4381, RNA1509_36471} {RNA1509_36471, RNA815_6050}

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