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Results for MligTC455_27981

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_27981 1573 32.77 Mlig455_014661

Neo: -

Age: -

Region-enriched R3: 1.975/0.00314

SLC9A3R2 Mlig455_014661 {REF} {Length: 2473} {Pfam: PDZ domain [PF00595.26, score=41.4]; PDZ domain [PF17820.3, score=26.4]; PDZ domain [PF13180.8, score=23.8]} {Human: ENSG00000065054, SLC9A3R2, SLC9A3 regulator 2, [RH, Score=97.4, Expect=7e-23]} {Mouse: ENSMUSG00000002504, Slc9a3r2, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2, [RH, Score=96.7, Expect=1e-22]; ENSMUSG00000020733, Slc9a3r1, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1, [RH, Score=95.9, Expect=3e-22]} {Dmel: FBgn0010620, CG10939, [Score=89.7, Expect=2e-20]} {Celegans: WBGene00006438, nrfl-1, NHERF (Mammalian Na/H Exchange Regulatory Factor) Like, [Score=92.4, Expect=5e-21]} {Smed: dd_Smed_v6_3039_0_1, dd_Smed_v6_3039_0_1, [Score=110, Expect=3e-29]} {RNA1509_39084} {RNA1310_17362} {RNA815_22754.1}

Cumulative graph for MligTC455_27981

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.379 5.299 0.70375 1.00000
RegionR2 -0.379 5.299 0.57794 0.93486
RegionR3 1.975 5.299 0.00006 0.00314
RegionR4 0.248 5.299 0.69091 0.98238
RegionR5 0.931 5.299 0.05305 0.19571
RegionR6 1.07 5.299 0.04216 0.38492
RegionR7 -1.119 5.299 0.10265 0.61074
RegionR8 -3.106 5.299 0.00117 0.05237

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.141 5.299 0.49030 1.00000
RegenerationR2 -0.337 5.299 0.63674 0.93015
RegenerationR3 -0.422 5.299 0.53434 0.87436
RegenerationR4 0.61 5.299 0.38737 0.80574
RegenerationR5 0.363 5.299 0.58721 0.90409
RegenerationR6 0.12 5.299 0.85516 1.00000
RegenerationBL 0.14 5.299 0.86620 1.00000
RegenerationTP 3.036 5.299 0.00019 0.01795


Genes with expression patterns similar to MligTC455_27981

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_27981 1573 32.77 Mlig455_014661

Neo: -

Age: -

Region-enriched R3: 1.975/0.00314

SLC9A3R2 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_014661 {REF} {Length: 2473} {Pfam: PDZ domain [PF00595.26, score=41.4]; PDZ domain [PF17820.3, score=26.4]; PDZ domain [PF13180.8, score=23.8]} {Human: ENSG00000065054, SLC9A3R2, SLC9A3 regulator 2, [RH, Score=97.4, Expect=7e-23]} {Mouse: ENSMUSG00000002504, Slc9a3r2, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2, [RH, Score=96.7, Expect=1e-22]; ENSMUSG00000020733, Slc9a3r1, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1, [RH, Score=95.9, Expect=3e-22]} {Dmel: FBgn0010620, CG10939, [Score=89.7, Expect=2e-20]} {Celegans: WBGene00006438, nrfl-1, NHERF (Mammalian Na/H Exchange Regulatory Factor) Like, [Score=92.4, Expect=5e-21]} {Smed: dd_Smed_v6_3039_0_1, dd_Smed_v6_3039_0_1, [Score=110, Expect=3e-29]} {RNA1509_39084} {RNA1310_17362} {RNA815_22754.1}
2. MligTC455_37180 372 7.75 Mlig455_020649

Neo: -

Age: Down-Up-Down

Region-enriched R3: 2.893/0.00005
Region-enriched R5: 1.749/0.04568

SAXO2 3.998 - 0.752 0.821 0.956 0.711 0.758 Mlig455_020649 {REF} {Length: 3369} {Human: ENSG00000188659, SAXO2, stabilizer of axonemal microtubules 2, [Score=56.6, Expect=3e-08]} {Mouse: ENSMUSG00000038570, Saxo2, stabilizer of axonemal microtubules 2, [Score=62.8, Expect=2e-10]} {Smed: dd_Smed_v6_12892_0_1, dd_Smed_v6_12892_0_1, [Score=48.1, Expect=5e-06]} {RNA1509_27202, RNA1509_41936} {RNA1310_7566, RNA1509_41936} {RNA1509_41936, RNA815_9731}
3. MligTC455_22472 1921 40.02 Mlig455_001851, Mlig455_001923

Neo: -

Age: logFC(26M/2M)=0.300

Region-enriched R5: 1.841/0.00024
Region-enriched R4: 1.791/0.00726
Region-enriched R3: 1.705/0.00436

DHRS1 3.66 - 0.872 0.920 0.951 - 0.917

Mlig455_001851 {REF} {Length: 2936} {TRANSSPLICED} {Pfam: short chain dehydrogenase [PF00106.27, score=117.0]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=99.8]; KR domain [PF08659.12, score=29.0]} {Human: ENSG00000284868, DHRS1, dehydrogenase/reductase 1, [RH, Score=295, Expect=4e-99]; ENSG00000157379, DHRS1, dehydrogenase/reductase 1, [RH, Score=295, Expect=4e-99]} {Mouse: ENSMUSG00000002332, Dhrs1, dehydrogenase/reductase (SDR family) member 1, [RH, Score=300, Expect=3e-101]} {Dmel: FBgn0039537, CG5590, [Score=84.7, Expect=4e-18]} {Celegans: WBGene00000973, dhs-9, DeHydrogenases, Short chain, [RH, Score=316, Expect=1e-107]} {Smed: dd_Smed_v6_956_0_1, dd_Smed_v6_956_0_1, [Score=89.0, Expect=8e-20]} {RNA1509_48116} {RNA1310_19863} {RNA815_7780}

Mlig455_001923 {REF} {Length: 3749} {TRANSSPLICED} {Pfam: short chain dehydrogenase [PF00106.27, score=233.4]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=189.0]; KR domain [PF08659.12, score=47.9]; Diiron non-heme beta-hydroxylase N-terminal domain [PF18456.3, score=19.2]} {Human: ENSG00000157379, DHRS1, dehydrogenase/reductase 1, [RH, Score=291, Expect=2e-93]; ENSG00000284868, DHRS1, dehydrogenase/reductase 1, [RH, Score=291, Expect=2e-93]} {Mouse: ENSMUSG00000002332, Dhrs1, dehydrogenase/reductase (SDR family) member 1, [RH, Score=296, Expect=1e-95]} {Dmel: FBgn0037354, CG12171, [Score=88.6, Expect=2e-19]} {Celegans: WBGene00000973, dhs-9, DeHydrogenases, Short chain, [RH, Score=313, Expect=2e-102]} {Smed: dd_Smed_v6_956_0_1, dd_Smed_v6_956_0_1, [Score=86.7, Expect=4e-18]} {RNA1509_48116} {RNA1310_19863} {RNA815_7780}
4. MligTC455_43138 1146 23.88 Mlig455_039103

Neo: -

Age: logFC(26M/2M)=-0.429

Region-enriched R3: 1.590/0.02842

SLC26A4 3.435 0.824 0.907 - 0.955 - 0.749 Mlig455_039103 {REF} {Length: 4282} {Pfam: Sulfate permease family [PF00916.22, score=277.2]; STAS domain [PF01740.23, score=82.1]} {Human: ENSG00000091137, SLC26A4, solute carrier family 26 member 4, [Score=385, Expect=2e-119]; ENSG00000170615, SLC26A5, solute carrier family 26 member 5, [Score=372, Expect=4e-115]} {Mouse: ENSMUSG00000029015, Slc26a5, solute carrier family 26, member 5, [Score=377, Expect=6e-117]; ENSMUSG00000020651, Slc26a4, solute carrier family 26, member 4, [Score=361, Expect=1e-110]} {Dmel: FBgn0036770, Prestin, [Score=224, Expect=1e-61]} {Celegans: WBGene00013963, sulp-8, Anion transporter SULP-8a; Anion transporter SULP-8b; SULfate Permease family, [Score=266, Expect=9e-78]} {Smed: dd_Smed_v6_8150_0_1, dd_Smed_v6_8150_0_1, [Score=389, Expect=3e-121]} {RNA1509_1752} {RNA1310_6089} {RNA815_419.1}
5. MligTC455_15686 5588 116.41 Mlig455_011058

Neo: -

Age: -

Region-enriched R3: 1.651/0.01200
Region-enriched R5: 1.436/0.01547

CRABP2 3.406 0.742 0.789 - 0.979 - 0.896 Mlig455_011058 {REF} {Length: 857} {Pfam: Lipocalin / cytosolic fatty-acid binding protein family [PF00061.25, score=54.9]; Lipocalin / cytosolic fatty-acid binding protein family [PF14651.8, score=29.1]} {Human: ENSG00000143320, CRABP2, cellular retinoic acid binding protein 2, [Score=95.5, Expect=1e-25]; ENSG00000170323, FABP4, fatty acid binding protein 4, [Score=91.7, Expect=3e-24]; ENSG00000121769, FABP3, fatty acid binding protein 3, [Score=91.3, Expect=4e-24]} {Mouse: ENSMUSG00000004885, Crabp2, cellular retinoic acid binding protein II, [Score=95.9, Expect=5e-26]; ENSMUSG00000027533, Fabp5, fatty acid binding protein 5, epidermal, [Score=93.2, Expect=5e-25]; ENSMUSG00000028773, Fabp3, fatty acid binding protein 3, muscle and heart, [Score=92.4, Expect=1e-24]} {Dmel: FBgn0037913, fabp, fatty acid binding protein, [Score=76.6, Expect=1e-18]} {Celegans: WBGene00002257, lbp-5, Fatty acid-binding protein homolog 5, [Score=100, Expect=6e-28]} {Smed: dd_Smed_v6_271_0_1, dd_Smed_v6_271_0_1, [RH, Score=102, Expect=6e-29]} {RNA1509_23333, RNA1509_23783, RNA1509_29966, RNA1509_3321, RNA1509_6404} {RNA1310_38135.2, RNA1509_23333, RNA1509_23783, RNA1509_29966, RNA1509_3321, RNA1509_6404} {RNA1509_23333, RNA1509_23783, RNA1509_29966, RNA1509_3321, RNA1509_6404, RNA815_30164}
6. MligTC455_24859 5590 116.45 Mlig455_054066, Mlig455_063284

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.306

Region-enriched R3: 2.202/0.00434

3.39 0.806 0.865 - 0.960 - 0.759

Mlig455_054066 {REF} {Length: 1406} {RNA1509_33411, RNA1509_7753} {RNA1310_22791, RNA1509_33411} {RNA1509_33411, RNA815_10514.1}

Mlig455_063284 {REF} {Length: 1414} {Pfam: Multi-glycosylated core protein 24 (MGC-24), sialomucin [PF05283.13, score=46.5]} {Mouse: ENSMUSG00000050912, Tmem123, transmembrane protein 123, [Score=46.6, Expect=2e-06]} {Dmel: FBgn0045823, vsg, visgun, [Score=53.1, Expect=8e-09]} {Smed: dd_Smed_v6_828_0_1, dd_Smed_v6_828_0_1, [RH, Score=53.5, Expect=2e-10]} {RNA1509_7753} {RNA1310_22791} {RNA815_10514.1}
7. MligTC455_41984 5794 120.71 Mlig455_070257

Neo: -

Age: logFC(26M/2M)=0.384

Region-enriched R3: 1.830/0.00014
Region-enriched R4: 1.696/0.00265
Region-enriched R6: 1.511/0.01084
Region-enriched R5: 1.493/0.00157

BHMT 3.381 0.820 0.796 - 0.810 - 0.955 Mlig455_070257 {REF} {Length: 2300} {Pfam: Homocysteine S-methyltransferase [PF02574.18, score=161.5]} {Human: ENSG00000145692, BHMT, betaine--homocysteine S-methyltransferase, [RH, Score=543, Expect=0.0]} {Mouse: ENSMUSG00000074768, Bhmt, betaine-homocysteine methyltransferase, [RH, Score=548, Expect=0.0]; ENSMUSG00000069324, Gm5096, predicted gene 5096, [RH, Score=548, Expect=0.0]} {Smed: dd_Smed_v6_873_0_1, dd_Smed_v6_873_0_1, [RH, Score=555, Expect=0.0]} {RNA1509_10637, RNA1509_54311, RNA1509_9980} {RNA1310_18981.1, RNA1509_54311, RNA1509_9980} {RNA1509_54311, RNA1509_9980, RNA815_5900.2}
8. MligTC455_53353 785 16.35 Mlig455_054576

Neo: -

Age: -

Region-enriched R5: 1.236/0.00860

3.376 0.745 0.791 0.881 0.959 - - Mlig455_054576 {REF} {Length: 1561} {NoTransDecoderORF} {tRNA: Val(CAC),pseudo, score=24.3} {RNA1509_14965} {RNA1310_43218} {RNA815_25069}
9. MligTC455_27869 8765 182.6 Mlig455_051857, Mlig455_051868, Mlig455_051893

Neo: -

Age: Down-Down-Up

Region-enriched R3: 2.214/0.00040
Region-enriched R5: 1.603/0.01133

ANPEP 3.365 0.750 0.724 - 0.971 - 0.920

Mlig455_051857 {REF} {Length: 3680} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=260.1]; Peptidase family M1 domain [PF01433.22, score=238.0]; Peptidase M1 N-terminal domain [PF17900.3, score=137.9]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=560, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [RH, Score=546, Expect=6e-179]} {Dmel: FBgn0039640, CG14516, [RH, Score=536, Expect=1e-174]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=405, Expect=2e-125]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=599, Expect=0.0]} {RNA1509_5196} {RNA1310_2955.1} {RNA815_759.2}

Mlig455_051868 {REF} {Length: 4344} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=259.5]; Peptidase family M1 domain [PF01433.22, score=234.1]; Peptidase M1 N-terminal domain [PF17900.3, score=137.9]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=552, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [Score=542, Expect=4e-177]} {Dmel: FBgn0039640, CG14516, [RH, Score=529, Expect=7e-172]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=406, Expect=1e-125]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=595, Expect=0.0]} {RNA1509_5196} {RNA1310_2955.1} {RNA815_759.2}

Mlig455_051893 {REF} {Length: 4373} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=260.1]; Peptidase family M1 domain [PF01433.22, score=236.2]; Peptidase M1 N-terminal domain [PF17900.3, score=137.9]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=558, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [RH, Score=545, Expect=3e-178]} {Dmel: FBgn0039640, CG14516, [RH, Score=533, Expect=2e-173]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=405, Expect=2e-125]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=596, Expect=0.0]} {RNA1509_5196} {RNA1310_2955.1} {RNA815_759.2}
10. MligTC455_33577 18072 376.49 Mlig455_043957, Mlig455_043969, Mlig455_044039

Neo: -

Age: logFC(26M/2M)=0.423

Region-enriched R5: 1.425/0.00134
Region-enriched R4: 1.282/0.02044

IDH1 3.363 0.709 0.796 - 0.962 - 0.896

Mlig455_043957 {REF} {Length: 2414} {Pfam: Isocitrate/isopropylmalate dehydrogenase [PF00180.22, score=266.7]} {Human: ENSG00000138413, IDH1, isocitrate dehydrogenase (NADP(+)) 1, cytosolic, [RH, Score=664, Expect=0.0]} {Mouse: ENSMUSG00000025950, Idh1, isocitrate dehydrogenase 1 (NADP+), soluble, [RH, Score=660, Expect=0.0]} {Dmel: FBgn0001248, Idh, Isocitrate dehydrogenase, [RH, Score=636, Expect=0.0]} {Celegans: WBGene00010317, idh-1, Isocitrate dehydrogenase [NADP], [RH, Score=651, Expect=0.0]} {Smed: dd_Smed_v6_3770_0_1, dd_Smed_v6_3770_0_1, [RH, Score=652, Expect=0.0]} {RNA1509_16912} {RNA1310_10691.1, RNA1509_16912} {RNA1509_16912, RNA815_3934}

Mlig455_043969 {REF} {Length: 2413} {Pfam: Isocitrate/isopropylmalate dehydrogenase [PF00180.22, score=267.0]} {Human: ENSG00000138413, IDH1, isocitrate dehydrogenase (NADP(+)) 1, cytosolic, [RH, Score=667, Expect=0.0]} {Mouse: ENSMUSG00000025950, Idh1, isocitrate dehydrogenase 1 (NADP+), soluble, [RH, Score=664, Expect=0.0]} {Dmel: FBgn0001248, Idh, Isocitrate dehydrogenase, [RH, Score=639, Expect=0.0]} {Celegans: WBGene00010317, idh-1, Isocitrate dehydrogenase [NADP], [RH, Score=654, Expect=0.0]} {Smed: dd_Smed_v6_3770_0_1, dd_Smed_v6_3770_0_1, [RH, Score=655, Expect=0.0]} {RNA1509_16912, RNA1509_26642, RNA1509_847} {RNA1310_10691.1, RNA1509_26642, RNA1509_847} {RNA1509_26642, RNA1509_847, RNA815_3934}

Mlig455_044039 {REF} {Length: 2905} {Pfam: Isocitrate/isopropylmalate dehydrogenase [PF00180.22, score=267.0]} {Human: ENSG00000138413, IDH1, isocitrate dehydrogenase (NADP(+)) 1, cytosolic, [RH, Score=667, Expect=0.0]} {Mouse: ENSMUSG00000025950, Idh1, isocitrate dehydrogenase 1 (NADP+), soluble, [RH, Score=664, Expect=0.0]} {Dmel: FBgn0001248, Idh, Isocitrate dehydrogenase, [RH, Score=639, Expect=0.0]} {Celegans: WBGene00010317, idh-1, Isocitrate dehydrogenase [NADP], [RH, Score=654, Expect=0.0]} {Smed: dd_Smed_v6_3770_0_1, dd_Smed_v6_3770_0_1, [RH, Score=655, Expect=0.0]} {RNA1509_16912, RNA1509_38467} {RNA1310_10691.1, RNA1509_38467} {RNA1509_38467, RNA815_3934}
11. MligTC455_42438 2020 42.09 Mlig455_055199, Mlig455_055244

Neo: -

Age: -

Region-enriched R3: 2.265/0.00232

3.35 0.768 0.876 - 0.951 - 0.755

Mlig455_055199 {REF} {Length: 6274} {Pfam: Pyruvate phosphate dikinase, AMP/ATP-binding domain [PF01326.21, score=226.3]; PEP-utilising enzyme, mobile domain [PF00391.25, score=75.8]} {Dmel: FBgn0040342, CG3706, [RH, Score=132, Expect=4e-32]} {Celegans: WBGene00011893, T21C9.6, [RH, Score=307, Expect=3e-86]} {Smed: dd_Smed_v6_2604_0_1, dd_Smed_v6_2604_0_1, [RH, Score=855, Expect=0.0]} {RNA1509_1405, RNA1509_6581} {RNA1310_1331, RNA1509_6581} {RNA1509_6581, RNA815_563}

Mlig455_055244 {REF} {Length: 5074} {Pfam: Pyruvate phosphate dikinase, AMP/ATP-binding domain [PF01326.21, score=202.1]} {Dmel: FBgn0040342, CG3706, [RH, Score=132, Expect=8e-33]} {Celegans: WBGene00011893, T21C9.6, [Score=155, Expect=7e-39]} {Smed: dd_Smed_v6_2604_0_1, dd_Smed_v6_2604_0_1, [Score=466, Expect=1e-147]} {RNA1509_1405} {RNA1310_1331} {RNA815_563}
12. MligTC455_53352 700 14.58 Mlig455_036407

Neo: -

Age: Up-Down-Down

Region-enriched R5: 1.358/0.00516

DDO 3.34 0.733 0.790 0.850 0.967 - - Mlig455_036407 {REF} {Length: 2623} {TRANSSPLICED} {Pfam: FAD dependent oxidoreductase [PF01266.26, score=119.0]} {Human: ENSG00000203797, DDO, D-aspartate oxidase, [Score=163, Expect=2e-46]} {Mouse: ENSMUSG00000063428, Ddo, D-aspartate oxidase, [Score=162, Expect=2e-46]} {Dmel: FBgn0033543, CG12338, [Score=166, Expect=2e-48]} {Celegans: WBGene00008127, ddo-1, D-aspartate oxidase 1, [Score=137, Expect=2e-37]} {Smed: dd_Smed_v6_3560_0_1, dd_Smed_v6_3560_0_1, [Score=137, Expect=1e-37]} {RNA1509_27750, RNA1509_28502, RNA1509_8790} {RNA1310_23222, RNA1509_27750, RNA1509_28502, RNA1509_8790} {RNA1509_27750, RNA1509_28502, RNA1509_8790, RNA815_10774}
13. MligTC455_18812 1757 36.61 Mlig455_065119

Neo: -

Age: Down-Up-Up

Region-enriched R5: 1.432/0.00000
Region-enriched R4: 1.301/0.00178
Region-enriched R3: 1.037/0.00898

HACD2 3.322 0.700 0.733 0.925 0.964 - - Mlig455_065119 {REF} {Length: 1401} {TRANSSPLICED} {Pfam: Protein tyrosine phosphatase-like protein, PTPLA [PF04387.16, score=198.0]} {Human: ENSG00000206527, HACD2, 3-hydroxyacyl-CoA dehydratase 2, [RH, Score=197, Expect=9e-63]} {Mouse: ENSMUSG00000035376, Hacd2, 3-hydroxyacyl-CoA dehydratase 2, [RH, Score=199, Expect=8e-64]} {Dmel: FBgn0032394, CG6746, [RH, Score=146, Expect=3e-43]} {Celegans: WBGene00020517, hpo-8, Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase hpo-8, [RH, Score=178, Expect=2e-56]} {Smed: dd_Smed_v6_1743_0_1, dd_Smed_v6_1743_0_1, [RH, Score=157, Expect=3e-48]} {RNA1509_10560, RNA1509_15847, RNA1509_27091, RNA1509_46240, RNA1509_47631, RNA1509_8698} {RNA1310_23405.1, RNA1509_10560, RNA1509_15847, RNA1509_27091, RNA1509_46240, RNA1509_47631} {RNA1509_10560, RNA1509_15847, RNA1509_27091, RNA1509_46240, RNA1509_47631, RNA815_24657}
14. MligTC455_48012 225 4.68 Mlig455_021532

Neo: -

Age: Down-Up-Down

Region-enriched R3: 2.619/0.00051

3.303 0.773 0.797 - 0.983 - 0.750 Mlig455_021532 {REF} {Length: 854} {Celegans: WBGene00044743, crb-3, Drosophila CRumBs homolog, [RH, Score=44.7, Expect=2e-07]} {RNA1509_16097} {RNA1310_12897} {RNA815_7368}
15. MligTC455_47879 2386 49.71 Mlig455_031211

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.530

3.3 0.737 0.881 - 0.961 - 0.721 Mlig455_031211 {REF} {Length: 989} {Pfam: Wnt and FGF inhibitory regulator [PF13908.8, score=20.1]} {RNA1509_49697, RNA1509_6639} {RNA1310_43777, RNA1509_49697, RNA1509_6639} {RNA1509_49697, RNA1509_6639, RNA815_26112.1}
16. MligTC455_05783 1663 34.65 Mlig455_035867, Mlig455_035905

Neo: -

Age: -

Region-enriched R3: 2.280/0.00011
Region-enriched R6: 1.801/0.01554
Region-enriched R5: 1.266/0.03642

3.294 0.803 - 0.728 0.953 - 0.810

Mlig455_035867 {REF} {Length: 4052} {Pfam: Beta-lactamase [PF00144.26, score=75.6]} {Smed: dd_Smed_v6_35168_0_1, dd_Smed_v6_35168_0_1, [RH, Score=51.6, Expect=2e-07]} {RNA1509_5240} {RNA1310_3628.1} {RNA815_4303}

Mlig455_035905 {REF} {Length: 4358} {Pfam: Beta-lactamase [PF00144.26, score=75.6]} {Smed: dd_Smed_v6_35168_0_1, dd_Smed_v6_35168_0_1, [RH, Score=51.6, Expect=2e-07]} {RNA1509_25549, RNA1509_36720, RNA1509_5240} {RNA1310_3628.1, RNA1509_25549, RNA1509_36720, RNA1509_5240} {RNA1509_25549, RNA1509_36720, RNA1509_5240, RNA815_4303}
17. MligTC455_48013 466 9.71 Mlig455_021266, Mlig455_021536

Neo: -

Age: Down-Down-Up

Region-enriched R3: 2.379/0.00063

3.221 0.715 0.789 - 0.982 - 0.735

Mlig455_021266 {REF} {Length: 2111} {Pfam: EGF-like domain [PF00008.29, score=19.9]} {Mouse: ENSMUSG00000028369, Svep1, sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1, [Score=52.4, Expect=9e-07]} {Dmel: FBgn0004647, N, Notch, [Score=62.8, Expect=5e-10]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=48.1, Expect=1e-05]} {RNA1509_16097, RNA1509_29659} {RNA1310_12897, RNA1509_29659} {RNA1509_29659, RNA815_7368}

Mlig455_021536 {REF} {Length: 2137} {Pfam: EGF-like domain [PF00008.29, score=19.9]} {Mouse: ENSMUSG00000028369, Svep1, sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1, [Score=52.4, Expect=9e-07]} {Dmel: FBgn0004647, N, Notch, [Score=62.8, Expect=5e-10]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=48.1, Expect=1e-05]} {RNA1509_16097} {RNA1310_12897, RNA1509_16097} {RNA1509_16097, RNA815_7368}
18. MligTC455_41521 1793 37.36 Mlig455_057588

Neo: -

Age: -

Region-enriched R5: 1.375/0.00000
Region-enriched R3: 1.257/0.00033
Region-enriched R4: 1.049/0.01657

3.186 0.747 0.723 0.749 0.967 - - Mlig455_057588 {REF} {Length: 2069} {TRANSSPLICED} {RNA1509_22303, RNA1509_3842, RNA1509_41783, RNA1509_9152} {RNA1310_16812.1, RNA1509_22303, RNA1509_3842, RNA1509_41783, RNA1509_9152} {RNA1509_22303, RNA1509_3842, RNA1509_41783, RNA1509_9152, RNA815_17534}
19. MligTC455_18737 1898 39.54 Mlig455_043481

Neo: -

Age: -

Region-enriched R4: 1.350/0.00054
Region-enriched R5: 1.308/0.00001
Region-enriched R3: 1.024/0.00612

RAB32 2.757 - 0.912 - 0.977 - 0.868 Mlig455_043481 {REF} {Length: 2268} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=147.5]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=102.0]; ADP-ribosylation factor family [PF00025.23, score=45.9]; Gtr1/RagA G protein conserved region [PF04670.14, score=25.0]; Elongation factor Tu GTP binding domain [PF00009.29, score=23.7]} {Human: ENSG00000118508, RAB32, RAB32, member RAS oncogene family, [RH, Score=268, Expect=6e-91]; ENSG00000123892, RAB38, RAB38, member RAS oncogene family, [RH, Score=255, Expect=4e-86]} {Mouse: ENSMUSG00000019832, Rab32, RAB32, member RAS oncogene family, [RH, Score=263, Expect=5e-89]; ENSMUSG00000030559, Rab38, RAB38, member RAS oncogene family, [RH, Score=257, Expect=6e-87]} {Dmel: FBgn0002567, Rab32, [RH, Score=282, Expect=3e-91]} {Celegans: WBGene00011083, glo-1, Gut granule LOss; Rab GTPase GLO-1, [Score=187, Expect=6e-60]} {Smed: dd_Smed_v6_1037_0_1, dd_Smed_v6_1037_0_1, [RH, Score=247, Expect=2e-83]} {RNA1509_40760, RNA1509_7881} {RNA1310_29704.1, RNA1509_40760, RNA1509_7881} {RNA1509_40760, RNA1509_7881, RNA815_11258}
20. MligTC455_34695 309 6.44 Mlig455_018530

Neo: -

Age: -

Region-enriched R3: 4.486/0.00000
Region-enriched R5: 3.375/0.00129

CYP2C8 2.746 - 0.877 0.907 0.962 - - Mlig455_018530 {REF} {Length: 2705} {Pfam: Cytochrome P450 [PF00067.24, score=331.1]} {Human: ENSG00000138115, CYP2C8, cytochrome P450 family 2 subfamily C member 8, [RH, Score=285, Expect=6e-90]; ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=271, Expect=1e-83]} {Mouse: ENSMUSG00000074254, Cyp2a4, cytochrome P450, family 2, subfamily a, polypeptide 4, [RH, Score=276, Expect=1e-86]; ENSMUSG00000032808, Cyp2c38, cytochrome P450, family 2, subfamily c, polypeptide 38, [RH, Score=276, Expect=1e-86]; ENSMUSG00000005547, Cyp2a5, cytochrome P450, family 2, subfamily a, polypeptide 5, [RH, Score=273, Expect=4e-85]; ENSMUSG00000116063, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [RH, Score=270, Expect=1e-83]; ENSMUSG00000027983, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [RH, Score=270, Expect=1e-83]; ENSMUSG00000025003, Cyp2c39, cytochrome P450, family 2, subfamily c, polypeptide 39, [RH, Score=268, Expect=3e-83]; ENSMUSG00000060613, Cyp2c70, cytochrome P450, family 2, subfamily c, polypeptide 70, [RH, Score=265, Expect=2e-82]; ENSMUSG00000067229, Cyp2c66, cytochrome P450, family 2, subfamily c, polypeptide 66, [RH, Score=265, Expect=2e-82]} {Dmel: FBgn0036910, Cyp305a1, [RH, Score=211, Expect=1e-61]} {Celegans: WBGene00016860, cyp-33C9, CYtochrome P450 family, [RH, Score=266, Expect=4e-83]} {Smed: dd_Smed_v6_3919_0_2, dd_Smed_v6_3919_0_2, [RH, Score=300, Expect=8e-96]} {RNA1509_13304} {RNA1310_8293.2, RNA1509_13304} {RNA1509_13304, RNA815_6048}
21. MligTC455_24540 1167 24.31 Mlig455_055702

Neo: -

Age: logFC(26M/2M)=0.284

Region-enriched R3: 1.388/0.00022

2.697 - 0.808 - 0.960 - 0.929 Mlig455_055702 {REF} {Length: 1950} {TRANSSPLICED} {RNA1509_10366, RNA1509_17902, RNA1509_6131} {RNA1310_27373, RNA1509_10366, RNA1509_17902} {RNA1509_10366, RNA1509_17902, RNA815_10944}
22. MligTC455_43368 6858 142.86 Mlig455_048986, Mlig455_049002

Neo: -

Age: Up-Down-Down

ACHE 2.659 0.797 0.906 - - - 0.956

Mlig455_048986 {REF} {Length: 14781} {Pfam: Carboxylesterase family [PF00135.30, score=2484.2]; alpha/beta hydrolase fold [PF07859.15, score=129.3]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=238, Expect=8e-66]} {Mouse: ENSMUSG00000058019, Ces5a, carboxylesterase 5A, [RH, Score=209, Expect=1e-56]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=189, Expect=3e-49]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=213, Expect=1e-57]} {Smed: dd_Smed_v6_10334_0_1, dd_Smed_v6_10334_0_1, [Score=202, Expect=8e-54]} {RNA1509_1156, RNA1509_14744, RNA1509_15426, RNA1509_18645, RNA1509_25748, RNA1509_38830, RNA1509_6237, RNA1509_82, RNA1509_8879} {RNA1310_83.1, RNA1509_1156, RNA1509_14744, RNA1509_15426, RNA1509_18645, RNA1509_25748, RNA1509_38830, RNA1509_6237, RNA1509_8879} {RNA1509_1156, RNA1509_14744, RNA1509_15426, RNA1509_18645, RNA1509_25748, RNA1509_38830, RNA1509_6237, RNA1509_8879, RNA815_40.1}

Mlig455_049002 {REF} {Length: 15214} {Pfam: Carboxylesterase family [PF00135.30, score=2695.8]; alpha/beta hydrolase fold [PF07859.15, score=131.9]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=238, Expect=1e-65]} {Mouse: ENSMUSG00000058019, Ces5a, carboxylesterase 5A, [RH, Score=211, Expect=7e-57]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=191, Expect=5e-50]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=207, Expect=1e-55]} {Smed: dd_Smed_v6_10334_0_1, dd_Smed_v6_10334_0_1, [Score=199, Expect=5e-53]} {RNA1509_82, RNA1509_8738} {RNA1310_83.1, RNA1509_8738} {RNA1509_8738, RNA815_40.1}
23. MligTC455_45590 6933 144.44 Mlig455_060243

Neo: -

Age: Up-Down-Down

Region-enriched R3: 1.918/0.00019

MRC1 2.641 0.865 0.825 - - - 0.951 Mlig455_060243 {REF} {Length: 4769} {Pfam: Lectin C-type domain [PF00059.23, score=548.8]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=62.0]; Extracellular link domain [PF00193.19, score=22.4]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [RH, Score=513, Expect=2e-156]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [RH, Score=485, Expect=1e-146]} {Dmel: FBgn0035199, tfc, triforce, [Score=57.4, Expect=8e-09]} {Celegans: WBGene00020191, clec-53, C-type LECtin, [RH, Score=103, Expect=1e-23]} {Smed: dd_Smed_v6_3193_0_2, dd_Smed_v6_3193_0_2, [Score=209, Expect=1e-54]} {RNA1509_169} {RNA1310_579} {RNA815_112.1}
24. MligTC455_34922 1849 38.53 Mlig455_030407, Mlig455_069030

Neo: -

Age: -

Region-enriched R5: 2.185/0.00224

2.638 - - 0.833 0.965 - 0.840

Mlig455_030407 {REF} {Length: 991} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=23.1]} {RNA1509_26310} {RNA1310_62659} {RNA815_52108}

Mlig455_069030 {REF} {Length: 800} {RNA1509_26310} {RNA1310_62659} {RNA815_52108}
25. MligTC455_49658 3392 70.66 Mlig455_011590

Neo: -

Age: -

Region-enriched R3: 1.949/0.00002

2.624 0.870 0.800 - - - 0.954 Mlig455_011590 {REF} {Length: 2376} {RNA1509_3964} {RNA1310_32368} {RNA815_14237.1}
26. MligTC455_34797 883 18.39 Mlig455_033462

Neo: -

Age: Up-Down-Up

Region-enriched R4: 1.410/0.04497

PZP 2.568 0.815 0.782 - 0.971 - - Mlig455_033462 {REF} {Length: 6119} {TRANSSPLICED} {Pfam: A-macroglobulin TED domain [PF07678.16, score=112.0]; A-macroglobulin receptor binding domain [PF07677.16, score=62.2]; Alpha-2-macroglobulin bait region domain [PF07703.16, score=55.9]; Alpha-2-macroglobulin family [PF00207.24, score=45.8]; MG2 domain [PF01835.21, score=35.2]; Macroglobulin domain MG3 [PF17791.3, score=21.3]} {Human: ENSG00000126838, PZP, PZP, alpha-2-macroglobulin like, [Score=179, Expect=2e-44]} {Mouse: ENSMUSG00000030111, A2m, alpha-2-macroglobulin, [Score=174, Expect=3e-43]; ENSMUSG00000030359, Pzp, PZP, alpha-2-macroglobulin like, [Score=171, Expect=3e-42]} {Dmel: FBgn0267488, Mcr, Macroglobulin complement-related, [RH, Score=531, Expect=1e-159]} {Celegans: WBGene00013969, tep-1, TEP (ThiolEster containing Protein), [Score=233, Expect=1e-61]} {Smed: dd_Smed_v6_3070_0_1, dd_Smed_v6_3070_0_1, [RH, Score=1325, Expect=0.0]} {RNA1509_8466} {RNA1310_642.1} {RNA815_286.1}
27. MligTC455_16017 1654 34.46 Mlig455_052747

Neo: -

Age: -

Region-enriched R4: 1.664/0.00032
Region-enriched R3: 1.084/0.03324

PM20D2 2.527 0.733 0.828 - - - 0.966 Mlig455_052747 {REF} {Length: 1787} {TRANSSPLICED} {Pfam: Peptidase dimerisation domain [PF07687.16, score=33.3]; Peptidase family M20/M25/M40 [PF01546.30, score=29.9]} {Human: ENSG00000146281, PM20D2, peptidase M20 domain containing 2, [RH, Score=356, Expect=5e-120]} {Mouse: ENSMUSG00000054659, Pm20d2, peptidase M20 domain containing 2, [RH, Score=355, Expect=1e-119]} {Smed: dd_Smed_v6_7395_0_1, dd_Smed_v6_7395_0_1, [RH, Score=337, Expect=9e-114]} {RNA1509_27696, RNA1509_38773, RNA1509_53331} {RNA1310_17432.1, RNA1509_27696, RNA1509_38773, RNA1509_53331} {RNA1509_27696, RNA1509_38773, RNA1509_53331, RNA815_6952}
28. MligTC455_49088 1114 23.21 Mlig455_011516

Neo: -

Age: -

Region-enriched R3: 1.223/0.01828
Region-enriched R4: 1.176/0.03574

2.492 0.730 0.805 - 0.957 - - Mlig455_011516 {REF} {Length: 816} {NoTransDecoderORF} {RNA1509_33665, RNA1509_7916} {RNA1310_16594, RNA1509_33665} {RNA1509_33665, RNA815_8276}
29. MligTC455_37947 220 4.59 Mlig455_052622

Neo: -

Age: logFC(26M/2M)=0.451

Region-enriched R3: 2.784/0.02131

2.488 - 0.732 - 0.951 0.805 - Mlig455_052622 {REF} {Length: 1774} {RNA1509_54490} {RNA1310_14110, RNA1509_54490} {RNA1509_54490, RNA815_23203}
30. MligTC455_14031 563 11.73 Mlig455_057422, Mlig455_063863

Neo: -

Age: logFC(26M/2M)=0.445

Region-enriched R3: 1.948/0.04587

LASP1 2.479 0.829 0.700 - 0.950 - -

Mlig455_057422 {REF} {Length: 2844} {Pfam: Variant SH3 domain [PF14604.8, score=50.4]; LIM domain [PF00412.24, score=47.3]; SH3 domain [PF00018.30, score=38.4]} {Human: ENSG00000002834, LASP1, LIM and SH3 protein 1, [Score=97.4, Expect=2e-22]; ENSG00000078114, NEBL, nebulette, [Score=94.4, Expect=2e-21]} {Mouse: ENSMUSG00000038366, Lasp1, LIM and SH3 protein 1, [Score=97.4, Expect=1e-22]; ENSMUSG00000053702, Nebl, nebulette, [Score=94.7, Expect=1e-21]} {Dmel: FBgn0063485, Lasp, [Score=106, Expect=6e-26]} {Celegans: WBGene00018367, F42H10.3, LIM and SH3 domain protein F42H10.3, [Score=102, Expect=2e-24]} {Smed: dd_Smed_v6_1218_0_1, dd_Smed_v6_1218_0_1, [Score=97.1, Expect=2e-23]} {RNA1509_26091} {RNA1310_14538} {RNA815_7715.1}

Mlig455_063863 {REF} {Length: 2948} {Pfam: Variant SH3 domain [PF14604.8, score=50.3]; LIM domain [PF00412.24, score=44.4]; SH3 domain [PF00018.30, score=38.3]} {Human: ENSG00000002834, LASP1, LIM and SH3 protein 1, [Score=95.9, Expect=7e-22]; ENSG00000078114, NEBL, nebulette, [Score=92.8, Expect=8e-21]} {Mouse: ENSMUSG00000038366, Lasp1, LIM and SH3 protein 1, [Score=95.9, Expect=4e-22]; ENSMUSG00000053702, Nebl, nebulette, [Score=93.2, Expect=4e-21]} {Dmel: FBgn0063485, Lasp, [Score=105, Expect=1e-25]} {Celegans: WBGene00018367, F42H10.3, LIM and SH3 domain protein F42H10.3, [Score=99.8, Expect=2e-23]} {Smed: dd_Smed_v6_1218_0_1, dd_Smed_v6_1218_0_1, [Score=96.3, Expect=4e-23]} {RNA1509_26091} {RNA1310_14538} {RNA815_7715.1}
31. MligTC455_44885 1182 24.62 Mlig455_046236

Neo: -

Age: logFC(26M/2M)=-0.476

Region-enriched R5: 1.329/0.00479
Region-enriched R4: 1.235/0.04372

CBS 2.391 0.712 - 0.722 0.957 - - Mlig455_046236 {REF} {Length: 2494} {TRANSSPLICED} {Pfam: Pyridoxal-phosphate dependent enzyme [PF00291.27, score=230.9]} {Human: ENSG00000160200, CBS, cystathionine-beta-synthase, [Score=223, Expect=2e-67]; ENSG00000274276, CBSL, cystathionine-beta-synthase like, [Score=223, Expect=2e-67]} {Mouse: ENSMUSG00000024039, Cbs, cystathionine beta-synthase, [Score=224, Expect=2e-68]} {Dmel: FBgn0031148, Cbs, centrosomin's beautiful sister, [Score=191, Expect=3e-56]} {Celegans: WBGene00010759, cysl-2, Bifunctional L-3-cyanoalanine synthase/cysteine synthase, [RH, Score=197, Expect=2e-60]} {Smed: dd_Smed_v6_1585_0_1, dd_Smed_v6_1585_0_1, [Score=203, Expect=8e-61]} {RNA1509_20532, RNA1509_33466, RNA1509_42465, RNA1509_48501, RNA1509_60061} {RNA1310_31449, RNA1509_20532, RNA1509_42465, RNA1509_48501, RNA1509_60061} {RNA1509_20532, RNA1509_42465, RNA1509_48501, RNA1509_60061, RNA815_11546.1}
32. MligTC455_04428 655 13.66 Mlig455_071088

Neo: -

Age: -

Region-enriched R4: 3.160/0.00859

1.882 - - 0.971 0.911 - - Mlig455_071088 {REF} {Length: 272} {NoTransDecoderORF} {RNA1509_284} {RNA1310_24413} {RNA815_6153}
33. MligTC455_44644 368 7.66 Mlig455_012549

Neo: -

Age: -

1.87 - - 0.893 0.977 - - Mlig455_012549 {REF} {Length: 1215} {NoTransDecoderORF} {RNA1509_48971} {RNA1310_7732} {RNA815_2578}
34. MligTC455_45337 3435 71.56 Mlig455_022362

Neo: -

Age: logFC(26M/2M)=-0.291

TXNRD1 1.847 - 0.888 - 0.959 - - Mlig455_022362 {REF} {Length: 2783} {TRANSSPLICED} {Pfam: Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=203.8]; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [PF02852.24, score=78.9]; Glutaredoxin [PF00462.26, score=69.1]; Pyridine nucleotide-disulphide oxidoreductase [PF00070.29, score=64.8]; Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=44.5]; Alanine dehydrogenase/PNT, C-terminal domain [PF01262.23, score=26.5]; FAD binding domain [PF00890.26, score=26.4]; Glucose inhibited division protein A [PF01134.24, score=20.9]; FAD dependent oxidoreductase [PF12831.9, score=20.8]; Thi4 family [PF01946.19, score=19.8]} {Human: ENSG00000198431, TXNRD1, thioredoxin reductase 1, [RH, Score=577, Expect=0.0]; ENSG00000197763, TXNRD3, thioredoxin reductase 3, [RH, Score=571, Expect=0.0]} {Mouse: ENSMUSG00000000811, Txnrd3, thioredoxin reductase 3, [RH, Score=563, Expect=0.0]} {Dmel: FBgn0020653, Trxr-1, Thioredoxin reductase-1, [RH, Score=484, Expect=1e-166]} {Celegans: WBGene00015553, trxr-1, Thioredoxin reductase 1, [RH, Score=486, Expect=5e-165]} {Smed: dd_Smed_v6_960_0_1, dd_Smed_v6_960_0_1, [RH, Score=590, Expect=0.0]} {RNA1509_1268, RNA1509_4098, RNA1509_7641} {RNA1310_6460.1, RNA1509_1268, RNA1509_4098, RNA1509_7641} {RNA1509_1268, RNA1509_4098, RNA1509_7641, RNA815_2233}
35. MligTC455_45589 8445 175.93 Mlig455_060231

Neo: -

Age: Up-Down-Down

Region-enriched R3: 2.105/0.00005

MRC1 1.768 0.813 - - - - 0.955 Mlig455_060231 {REF} {Length: 6599} {Pfam: Lectin C-type domain [PF00059.23, score=668.9]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=86.8]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [RH, Score=514, Expect=1e-153]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [RH, Score=487, Expect=3e-144]} {Dmel: FBgn0035199, tfc, triforce, [Score=57.4, Expect=1e-08]} {Celegans: WBGene00020191, clec-53, C-type LECtin, [RH, Score=103, Expect=2e-23]} {Smed: dd_Smed_v6_3193_0_2, dd_Smed_v6_3193_0_2, [Score=207, Expect=7e-54]} {RNA1509_14934, RNA1509_169, RNA1509_3659, RNA1509_3870} {RNA1310_579, RNA1509_14934, RNA1509_169, RNA1509_3659, RNA1509_3870} {RNA1509_14934, RNA1509_169, RNA1509_3659, RNA1509_3870, RNA815_112.1}
36. MligTC455_17769 618 12.87 Mlig455_051397

Neo: -

Age: logFC(26M/2M)=0.620

CYP4V2 1.754 - - 0.783 0.971 - - Mlig455_051397 {REF} {Length: 2080} {TRANSSPLICED} {Pfam: Cytochrome P450 [PF00067.24, score=310.4]} {Human: ENSG00000145476, CYP4V2, cytochrome P450 family 4 subfamily V member 2, [Score=379, Expect=2e-126]} {Mouse: ENSMUSG00000079057, Cyp4v3, cytochrome P450, family 4, subfamily v, polypeptide 3, [Score=377, Expect=6e-126]} {Dmel: FBgn0015032, Cyp4c3, Cytochrome P450-4c3, [Score=349, Expect=3e-115]} {Celegans: WBGene00013585, cyp-42A1, CYtochrome P450 family, [Score=327, Expect=6e-107]} {Smed: dd_Smed_v6_4319_0_1, dd_Smed_v6_4319_0_1, [Score=98.2, Expect=6e-22]} {RNA1509_60059} {RNA1310_9492} {RNA815_3644.1}
37. MligTC455_28707 1065 22.19 Mlig455_033092

Neo: -

Age: logFC(26M/2M)=0.629

Region-enriched R4: 2.478/0.00050
Region-enriched R3: 1.976/0.00423

1.752 - 0.802 - - - 0.950 Mlig455_033092 {REF} {Length: 2843} {Pfam: SH2 domain [PF00017.26, score=18.7]} {RNA1509_4794} {RNA1310_7767.1} {RNA815_2526}
38. MligTC455_37897 2648 55.16 Mlig455_067785

Neo: -

Age: -

Region-enriched R4: 1.209/0.00550
Region-enriched R3: 1.141/0.00424

1.745 0.786 - - 0.959 - - Mlig455_067785 {REF} {Length: 1455} {Smed: dd_Smed_v6_951_0_1, dd_Smed_v6_951_0_1, [RH, Score=59.7, Expect=5e-13]} {RNA1509_13477, RNA1509_1589, RNA1509_18881, RNA1509_30248} {RNA1310_12812.2, RNA1509_13477, RNA1509_18881, RNA1509_30248} {RNA1509_13477, RNA1509_18881, RNA1509_30248, RNA815_14113}
39. MligTC455_52027 2742 57.12 Mlig455_038451

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=2.259

Region-enriched R3: 2.048/0.00000
Region-enriched R5: 1.468/0.00009
Region-enriched R4: 1.426/0.00323

NPC2 1.739 0.774 - - - - 0.965 Mlig455_038451 {REF} {Length: 1128} {Pfam: ML domain [PF02221.17, score=98.8]} {Human: ENSG00000119655, NPC2, NPC intracellular cholesterol transporter 2, [RH, Score=127, Expect=1e-37]} {Mouse: ENSMUSG00000021242, Npc2, NPC intracellular cholesterol transporter 2, [Score=116, Expect=7e-34]} {Dmel: FBgn0031381, Npc2a, Niemann-Pick type C-2a, [RH, Score=129, Expect=8e-39]} {Smed: dd_Smed_v6_602_0_1, dd_Smed_v6_602_0_1, [RH, Score=129, Expect=3e-39]} {RNA1509_19406, RNA1509_27769, RNA1509_2995, RNA1509_4004, RNA1509_42381, RNA1509_45875, RNA1509_56738} {RNA1310_12229, RNA1509_19406, RNA1509_27769, RNA1509_2995, RNA1509_4004, RNA1509_42381, RNA1509_45875, RNA1509_56738} {RNA1509_19406, RNA1509_27769, RNA1509_2995, RNA1509_4004, RNA1509_42381, RNA1509_45875, RNA1509_56738, RNA815_4030}
40. MligTC455_13228 168 3.5 Mlig455_018476

Neo: -

Age: logFC(26M/2M)=0.882

Region-enriched R3: 2.619/0.02717
Region-enriched R5: 2.567/0.00530

1.72 0.758 - - 0.962 - - Mlig455_018476 {REF} {Length: 1977} {RNA1509_42284, RNA1509_43857} {RNA1310_32873, RNA1509_43857} {RNA1509_43857, RNA815_10899.1}
41. MligTC455_45640 354 7.37 Mlig455_044849

Neo: -

Age: -

Region-enriched R4: 1.921/0.00612

NFAT5 1.704 - 0.743 - 0.961 - - Mlig455_044849 {REF} {Length: 2286} {Human: ENSG00000102908, NFAT5, nuclear factor of activated T cells 5, [Score=70.1, Expect=3e-13]} {Mouse: ENSMUSG00000003847, Nfat5, nuclear factor of activated T cells 5, [Score=71.2, Expect=8e-14]} {Dmel: FBgn0030505, NFAT, NFAT nuclear factor, [Score=64.3, Expect=1e-11]} {Smed: dd_Smed_v6_5978_0_1, dd_Smed_v6_5978_0_1, [Score=75.5, Expect=1e-15]} {RNA1509_28577} {RNA1310_61235.1} {RNA815_20233.1}
42. MligTC455_45421 1113 23.18 Mlig455_061978

Neo: -

Age: Down-Down-Up

Region-enriched R4: 2.233/0.00214

1.693 0.737 - - 0.956 - - Mlig455_061978 {REF} {Length: 1540} {Pfam: Sleepless protein [PF17064.7, score=32.3]} {Celegans: WBGene00019663, K11H12.7, [RH, Score=58.2, Expect=3e-11]} {Smed: dd_Smed_v6_780_0_1, dd_Smed_v6_780_0_1, [RH, Score=53.1, Expect=3e-09]} {RNA1509_12407, RNA1509_19531, RNA1509_9020} {RNA1310_25351.3, RNA1509_12407, RNA1509_19531} {RNA1509_12407, RNA1509_19531, RNA815_8070}
43. MligTC455_17728 1061 22.09 Mlig455_057691

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-4.029

Region-enriched R6: 1.981/0.02890

1.687 - - - 0.954 - 0.733 Mlig455_057691 {REF} {Length: 717} {RNA1509_20501} {RNA1310_48596} {RNA815_26649}
44. MligTC455_38440 283 5.89 Mlig455_030244

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=1.790

Region-enriched R4: 4.854/0.00001
Region-enriched R3: 2.903/0.00805

PISD 1.684 - 0.733 - 0.951 - - Mlig455_030244 {REF} {Length: 2464} {Pfam: Phosphatidylserine decarboxylase [PF02666.17, score=105.9]} {Human: ENSG00000241878, PISD, phosphatidylserine decarboxylase, [RH, Score=178, Expect=1e-54]} {Mouse: ENSMUSG00000023452, Pisd, phosphatidylserine decarboxylase, [RH, Score=173, Expect=6e-53]} {Dmel: FBgn0026576, CG5991, [Score=137, Expect=2e-37]} {Celegans: WBGene00015159, psd-1, Phosphatidylserine decarboxylase proenzyme, mitochondrial Phosphatidylserine decarboxylase beta chain Phosphatidylserine decarboxylase alpha chain, [Score=116, Expect=2e-30]} {Smed: dd_Smed_v6_10310_0_2, dd_Smed_v6_10310_0_2, [Score=169, Expect=2e-50]} {RNA1509_28822} {RNA1310_18146} {RNA815_8466}
45. MligTC455_43722 889 18.52 Mlig455_066637

Neo: -

Age: -

Region-enriched R4: 1.670/0.03939
Region-enriched R5: 1.324/0.03995

1.662 - 0.707 - 0.955 - - Mlig455_066637 {REF} {Length: 3656} {TRANSSPLICED} {Pfam: Protein of unknown function (DUF1295) [PF06966.14, score=191.4]; 3-oxo-5-alpha-steroid 4-dehydrogenase [PF02544.18, score=27.0]; Phospholipid methyltransferase [PF04191.15, score=21.1]; Isoprenylcysteine carboxyl methyltransferase (ICMT) family [PF04140.16, score=20.9]} {Dmel: FBgn0035914, CG6282, [RH, Score=167, Expect=2e-49]} {Smed: dd_Smed_v6_14327_0_1, dd_Smed_v6_14327_0_1, [RH, Score=156, Expect=1e-45]} {RNA1509_17541, RNA1509_24503, RNA1509_27200, RNA1509_30241, RNA1509_35384, RNA1509_45024, RNA1509_59986, RNA1509_8023} {RNA1310_33212, RNA1509_17541, RNA1509_24503, RNA1509_27200, RNA1509_30241, RNA1509_45024, RNA1509_59986, RNA1509_8023} {RNA1509_17541, RNA1509_24503, RNA1509_27200, RNA1509_30241, RNA1509_45024, RNA1509_59986, RNA1509_8023, RNA815_13020.1}
46. MligTC455_13714 219 4.55 Mlig455_039476

Neo: -

Age: -

Region-enriched R4: 5.355/0.00070
Region-enriched R5: 3.269/0.00973

0.975 - - - 0.975 - - Mlig455_039476 {REF} {Length: 684} {NoTransDecoderORF} {RNA1509_296, RNA1509_36260, RNA1509_3658} {RNA1310_1675.1, RNA1509_296, RNA1509_3658} {RNA1509_296, RNA1509_3658, RNA815_2514.1}
47. MligTC455_36060 69 1.45 Mlig455_056811

Neo: -

Age: Up-Down-Down

0.974 - - - 0.974 - - Mlig455_056811 {REF} {Length: 2647} {Pfam: HEPN domain [PF05168.16, score=26.2]} {RNA1509_29577} {RNA1310_37309.1} {RNA815_5901.1}
48. MligTC455_46184 112 2.33 Mlig455_015504

Neo: -

Age: logFC(26M/2M)=0.252

Region-enriched R3: 2.970/0.01671

0.963 - - - 0.963 - - Mlig455_015504 {REF} {Length: 4433} {Pfam: Retinol binding protein receptor [PF14752.8, score=277.3]} {Mouse: ENSMUSG00000028327, Stra6l, STRA6-like, [Score=86.3, Expect=5e-17]} {Smed: dd_Smed_v6_10051_0_1, dd_Smed_v6_10051_0_1, [RH, Score=125, Expect=1e-29]} {RNA1509_20697, RNA1509_32253} {RNA1310_3008.1, RNA1509_20697, RNA1509_32253} {RNA1509_20697, RNA1509_32253, RNA815_2696.1}
49. MligTC455_46612 316 6.59 Mlig455_043814

Neo: Int S/G2/M

Age: -

Region-enriched R5: 1.224/0.02363

0.963 - - - 0.963 - - Mlig455_043814 {REF} {Length: 472} {TRANSSPLICED} {RNA1509_51416} {RNA1310_64156, RNA1509_51416} {RNA1509_51416, RNA815_40137}
50. MligTC455_19141 162 3.37 Mlig455_054393

Neo: Germline

Age: Up-Down-Down

0.961 - - - - 0.961 - Mlig455_054393 {REF} {Length: 960} {NoTransDecoderORF} {RNA1509_4877} {RNA1310_68666} {RNA815_20064}
51. MligTC455_19991 347 7.23 Mlig455_036903

Neo: Int S/G2/M

Age: Down-Up-Up

Region-enriched R5: 2.364/0.00153

0.961 - - - 0.961 - - Mlig455_036903 {REF} {Length: 461} {TRANSSPLICED} {RNA1509_28367, RNA1509_43308} {RNA1310_78029, RNA1509_43308} {RNA1509_43308, RNA815_40479}
52. MligTC455_34375 5245 109.27 Mlig455_068696

Neo: Int S/G2/M

Age: Down-Up-Up

Region-enriched R4: 1.179/0.00005

PAM16 0.959 - - - 0.959 - - Mlig455_068696 {REF} {Length: 859} {TRANSSPLICED} {Pfam: Pam16 [PF03656.15, score=123.4]} {Human: ENSG00000282228, PAM16, presequence translocase associated motor 16, [RH, Score=99.0, Expect=1e-26]; ENSG00000217930, PAM16, presequence translocase associated motor 16, [RH, Score=99.0, Expect=1e-26]} {Mouse: ENSMUSG00000045886, Gm9803, predicted gene 9803, [RH, Score=101, Expect=5e-28]; ENSMUSG00000014301, Pam16, presequence translocase-asssociated motor 16 homolog (S. cerevisiae), [RH, Score=101, Expect=5e-28]} {Dmel: FBgn0038387, blp, black pearl, [RH, Score=111, Expect=5e-32]} {Celegans: WBGene00009734, F45G2.8, Mitochondrial import inner membrane translocase subunit tim-16, [RH, Score=104, Expect=2e-29]} {Smed: dd_Smed_v6_1720_0_1, dd_Smed_v6_1720_0_1, [RH, Score=107, Expect=6e-31]} {RNA1509_17135, RNA1509_18372} {RNA1310_40855.1, RNA1509_18372} {RNA1509_18372, RNA815_19465}
53. MligTC455_36351 198 4.13 Mlig455_027673

Neo: -

Age: -

Region-enriched R4: 2.723/0.02760

ACP7 0.958 - - - - 0.958 - Mlig455_027673 {REF} {Length: 2184} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=88.8]; Purple acid Phosphatase, N-terminal domain [PF16656.7, score=76.0]; Iron/zinc purple acid phosphatase-like protein C [PF14008.8, score=73.9]; Ubiquitin-conjugating enzyme [PF00179.28, score=54.2]; PhoD-like phosphatase [PF09423.12, score=18.3]} {Human: ENSG00000183760, ACP7, acid phosphatase 7, tartrate resistant (putative), [RH, Score=425, Expect=2e-144]} {Mouse: ENSMUSG00000037469, Acp7, acid phosphatase 7, tartrate resistant, [RH, Score=442, Expect=2e-150]} {Dmel: FBgn0030245, CG1637, [RH, Score=422, Expect=4e-143]} {Celegans: WBGene00219316, F21A3.11, Purple acid phosphatase, [RH, Score=406, Expect=2e-136]} {Smed: dd_Smed_v6_1053_0_1, dd_Smed_v6_1053_0_1, [RH, Score=514, Expect=7e-180]} {RNA1509_9245} {RNA1310_47219} {RNA815_24182}
54. MligTC455_48966 1196 24.92 Mlig455_011970

Neo: -

Age: logFC(26M/2M)=0.730

Region-enriched R4: 2.185/0.00002
Region-enriched R5: 1.169/0.00499

0.958 - - - 0.958 - - Mlig455_011970 {REF} {Length: 667} {TRANSSPLICED} {Pfam: Type III secretion system lipoprotein chaperone (YscW) [PF09619.12, score=24.6]} {RNA1509_11772} {RNA1310_19739.1} {RNA815_20380}
55. MligTC455_53355 1190 24.78 Mlig455_033338, Mlig455_033357

Neo: -

Age: -

Region-enriched R4: 1.851/0.00149

0.958 - - - 0.958 - -

Mlig455_033338 {REF} {Length: 1291} {RNA1509_14712, RNA1509_46611} {RNA1310_36401.2, RNA1509_46611} {RNA1509_46611, RNA815_17710}

Mlig455_033357 {REF} {Length: 973} {TRANSSPLICED} {RNA1509_14712} {RNA1310_36401.2} {RNA815_17710}
56. MligTC455_56005 27 0.56 Mlig455_071040

Neo: -

Age: -

0.957 - - - 0.957 - - Mlig455_071040 {REF} {Length: 572} {NoTransDecoderORF} {RNA1509_284} {RNA1310_27375} {RNA815_6153}
57. MligTC455_16658 1547 32.23 Mlig455_056718, Mlig455_060300

Neo: -

Age: -

Region-enriched R3: 1.971/0.00155
Region-enriched R4: 1.653/0.02745

0.955 - - - - - 0.955

Mlig455_056718 {REF} {Length: 1714} {Pfam: Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=44.7]} {RNA1509_50620, RNA1509_51103, RNA1509_8737} {RNA1310_8838, RNA1509_50620, RNA1509_51103} {RNA1509_50620, RNA1509_51103, RNA815_7244}

Mlig455_060300 {REF} {Length: 1815} {Pfam: Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=46.9]} {Smed: dd_Smed_v6_855_0_1, dd_Smed_v6_855_0_1, [Score=47.0, Expect=5e-06]} {RNA1509_8737} {RNA1310_8838, RNA1509_8737} {RNA1509_8737, RNA815_7244}
58. MligTC455_18818 447 9.3 Mlig455_034930

Neo: -

Age: logFC(26M/2M)=-0.428

SMIM7 0.954 - - - 0.954 - - Mlig455_034930 {REF} {Length: 711} {Human: ENSG00000214046, SMIM7, small integral membrane protein 7, [RH, Score=74.3, Expect=5e-19]; ENSG00000268790, AC008764.4, novel protein, [RH, Score=70.9, Expect=1e-17]} {Mouse: ENSMUSG00000044600, Smim7, small integral membrane protein 7, [RH, Score=76.3, Expect=8e-20]} {Celegans: WBGene00021784, cogc-4, Conserved oligomeric Golgi complex subunit 4, [Score=73.6, Expect=5e-19]} {RNA1509_46415} {RNA1310_50894, RNA1509_46415} {RNA1509_46415, RNA815_26510.1}
59. MligTC455_41003 184 3.83 Mlig455_022941

Neo: -

Age: -

PNPLA2 0.954 - - - 0.954 - - Mlig455_022941 {REF} {Length: 4818} {TRANSSPLICED} {Pfam: Patatin-like phospholipase [PF01734.24, score=37.5]} {Human: ENSG00000177666, PNPLA2, patatin like phospholipase domain containing 2, [RH, Score=206, Expect=7e-59]} {Mouse: ENSMUSG00000025509, Pnpla2, patatin-like phospholipase domain containing 2, [RH, Score=204, Expect=2e-58]} {Dmel: FBgn0036449, bmm, brummer, [RH, Score=248, Expect=5e-74]} {Celegans: WBGene00015484, atgl-1, Patanin-like phospholipase domain-containing protein, [RH, Score=188, Expect=5e-51]} {Smed: dd_Smed_v6_9544_0_1, dd_Smed_v6_9544_0_1, [RH, Score=220, Expect=5e-64]} {RNA1509_31645} {RNA1310_13835} {RNA815_4510}
60. MligTC455_43147 1029 21.43 Mlig455_027559

Neo: -

Age: -

CTSC 0.954 - - - 0.954 - - Mlig455_027559 {REF} {Length: 2339} {TRANSSPLICED} {Pfam: Papain family cysteine protease [PF00112.25, score=214.3]; Cathepsin C exclusion domain [PF08773.13, score=113.1]; Peptidase C1-like family [PF03051.17, score=26.8]} {Human: ENSG00000109861, CTSC, cathepsin C, [RH, Score=474, Expect=1e-164]} {Mouse: ENSMUSG00000030560, Ctsc, cathepsin C, [RH, Score=436, Expect=6e-150]} {Dmel: FBgn0034709, Swim, Secreted Wg-interacting molecule, [Score=134, Expect=1e-34]} {Celegans: WBGene00000786, cpr-6, Cathepsin B-like cysteine proteinase 6, [Score=139, Expect=1e-36]} {Smed: dd_Smed_v6_219_0_1, dd_Smed_v6_219_0_1, [RH, Score=459, Expect=2e-159]} {RNA1509_4712} {RNA1310_11202.1} {RNA815_4097.1}
61. MligTC455_15158 423 8.81 Mlig455_039952

Neo: Int S/G2/M

Age: -

Region-specific R4: 5.765

Region-enriched R4: 4.205/0.00000

0.953 - - - 0.953 - - Mlig455_039952 {REF} {Length: 618} {NoTransDecoderORF} {RNA1509_13023} {RNA1310_50485, RNA1509_13023} {RNA1509_13023, RNA815_32374}
62. MligTC455_28838 84 1.75 Mlig455_007557

Neo: -

Age: -

Region-enriched R4: 3.260/0.01289
Region-enriched R5: 2.662/0.02640

0.951 - - - 0.951 - - Mlig455_007557 {REF} {Length: 745} {RNA1310_66594.1} {RNA815_40011}
63. MligTC455_50224 7563 157.56 Mlig455_047652

Neo: -

Age: Down-Up-Up

Region-enriched R6: 1.914/0.00000

AL928654.3 0.951 - - - 0.951 - - Mlig455_047652 {REF} {Length: 1157} {Pfam: LIM domain [PF00412.24, score=44.1]} {Human: ENSG00000257341, AL928654.3, novel transcript, [Score=87.0, Expect=1e-24]; ENSG00000213145, CRIP1, cysteine rich protein 1, [Score=87.0, Expect=1e-24]} {Mouse: ENSMUSG00000006360, Crip1, cysteine-rich protein 1 (intestinal), [Score=86.3, Expect=8e-24]} {Dmel: FBgn0039055, Rassf, Ras association family member, [Score=59.3, Expect=2e-12]} {Celegans: WBGene00017644, exc-9, [Score=76.3, Expect=1e-20]} {Smed: dd_Smed_v6_373_0_1, dd_Smed_v6_373_0_1, [Score=43.5, Expect=4e-07]} {RNA1509_19945} {RNA1310_16647.1} {RNA815_7231.3}
64. MligTC455_16722 2022 42.12 Mlig455_001580, Mlig455_060120

Neo: -

Age: -

SORT1 0.95 - - - 0.950 - -

Mlig455_001580 {REF} {Length: 3841} {Pfam: Sortilin, neurotensin receptor 3, [PF15902.7, score=246.2]; Sortilin, neurotensin receptor 3, C-terminal [PF15901.7, score=88.9]; BNR/Asp-box repeat [PF02012.22, score=30.9]; BNR repeat-like domain [PF13088.8, score=18.1]} {Human: ENSG00000134243, SORT1, sortilin 1, [Score=328, Expect=7e-99]} {Mouse: ENSMUSG00000068747, Sort1, sortilin 1, [Score=335, Expect=2e-101]} {Smed: dd_Smed_v6_1666_0_1, dd_Smed_v6_1666_0_1, [Score=483, Expect=1e-158]} {RNA1509_1193, RNA1509_27254} {RNA1310_4487, RNA1509_27254} {RNA1509_27254, RNA815_1034}

Mlig455_060120 {REF} {Length: 4319} {Pfam: Sortilin, neurotensin receptor 3, [PF15902.7, score=247.3]; Sortilin, neurotensin receptor 3, C-terminal [PF15901.7, score=111.1]; BNR/Asp-box repeat [PF02012.22, score=30.6]} {Human: ENSG00000134243, SORT1, sortilin 1, [RH, Score=350, Expect=4e-107]} {Mouse: ENSMUSG00000068747, Sort1, sortilin 1, [RH, Score=363, Expect=4e-112]} {Smed: dd_Smed_v6_1666_0_1, dd_Smed_v6_1666_0_1, [RH, Score=514, Expect=1e-170]} {RNA1509_1193, RNA1509_9859} {RNA1310_4487, RNA1509_1193, RNA1509_9859} {RNA1509_1193, RNA1509_9859, RNA815_1034}
65. MligTC455_47971 205 4.27 Mlig455_053905

Neo: -

Age: -

Region-enriched R5: 1.584/0.01760

PNPLA6 0.95 - - - 0.950 - - Mlig455_053905 {REF} {Length: 2153} {Pfam: Leucine carboxyl methyltransferase [PF04072.16, score=80.7]; Patatin-like phospholipase [PF01734.24, score=64.3]; Cyclic nucleotide-binding domain [PF00027.31, score=51.1]} {Human: ENSG00000032444, PNPLA6, patatin like phospholipase domain containing 6, [Score=326, Expect=4e-91]} {Mouse: ENSMUSG00000004565, Pnpla6, patatin-like phospholipase domain containing 6, [Score=323, Expect=3e-90]} {Dmel: FBgn0003656, sws, swiss cheese, [Score=294, Expect=1e-80]} {Celegans: WBGene00007137, B0285.4, Probable leucine carboxyl methyltransferase 1, [RH, Score=205, Expect=2e-58]} {Smed: dd_Smed_v6_11184_0_2, dd_Smed_v6_11184_0_2, [Score=305, Expect=1e-84]} {RNA1509_9655} {RNA1310_3015} {RNA815_10596}

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