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Results for MligTC455_48012

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_48012 225 4.68 Mlig455_021532

Neo: -

Age: Down-Up-Down

Region-enriched R3: 2.619/0.00051

Mlig455_021532 {REF} {Length: 854} {Celegans: WBGene00044743, crb-3, Drosophila CRumBs homolog, [RH, Score=44.7, Expect=2e-07]} {RNA1509_16097} {RNA1310_12897} {RNA815_7368}

Cumulative graph for MligTC455_48012

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.879 2.999 0.43642 1.00000
RegionR2 -0.918 2.999 0.39984 0.79414
RegionR3 2.619 2.999 0.00001 0.00051
RegionR4 1.141 2.999 0.07991 0.26464
RegionR5 1.472 2.999 0.01223 0.06690
RegionR6 1.297 2.999 0.06992 0.49279
RegionR7 -1.968 2.999 0.22738 0.84873
RegionR8 -1.763 2.999 0.37382 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -3.291 2.999 0.62422 1.00000
RegenerationR2 0.677 2.999 0.42087 0.82794
RegenerationR3 0.341 2.999 0.48572 0.85333
RegenerationR4 1.058 2.999 0.04682 0.34940
RegenerationR5 0.726 2.999 0.11736 0.51506
RegenerationR6 0.889 2.999 0.11203 0.41241
RegenerationBL 1.396 2.999 0.23637 0.58996
RegenerationTP 2.34 2.999 0.10575 0.50345


Genes with expression patterns similar to MligTC455_48012

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_48012 225 4.68 Mlig455_021532

Neo: -

Age: Down-Up-Down

Region-enriched R3: 2.619/0.00051

6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_021532 {REF} {Length: 854} {Celegans: WBGene00044743, crb-3, Drosophila CRumBs homolog, [RH, Score=44.7, Expect=2e-07]} {RNA1509_16097} {RNA1310_12897} {RNA815_7368}
2. MligTC455_48013 466 9.71 Mlig455_021266, Mlig455_021536

Neo: -

Age: Down-Down-Up

Region-enriched R3: 2.379/0.00063

5.963 0.974 0.994 0.998 1.000 0.999 0.998

Mlig455_021266 {REF} {Length: 2111} {Pfam: EGF-like domain [PF00008.29, score=19.9]} {Mouse: ENSMUSG00000028369, Svep1, sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1, [Score=52.4, Expect=9e-07]} {Dmel: FBgn0004647, N, Notch, [Score=62.8, Expect=5e-10]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=48.1, Expect=1e-05]} {RNA1509_16097, RNA1509_29659} {RNA1310_12897, RNA1509_29659} {RNA1509_29659, RNA815_7368}

Mlig455_021536 {REF} {Length: 2137} {Pfam: EGF-like domain [PF00008.29, score=19.9]} {Mouse: ENSMUSG00000028369, Svep1, sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1, [Score=52.4, Expect=9e-07]} {Dmel: FBgn0004647, N, Notch, [Score=62.8, Expect=5e-10]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=48.1, Expect=1e-05]} {RNA1509_16097} {RNA1310_12897, RNA1509_16097} {RNA1509_16097, RNA815_7368}
3. MligTC455_34132 637 13.26 Mlig455_001144, Mlig455_001306

Neo: -

Age: logFC(26M/2M)=-0.466

Region-enriched R3: 2.010/0.00006
Region-enriched R5: 1.734/0.00009

4.296 0.726 0.789 - 0.905 0.953 0.923

Mlig455_001144 {REF} {Length: 2159} {Pfam: Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=23.7]; Baculovirus immediate-early protein (IE-0) [PF05290.13, score=23.1]} {RNA1509_32599} {RNA1310_21009} {RNA815_32959}

Mlig455_001306 {REF} {Length: 2354} {Pfam: Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=23.6]} {RNA1310_21009} {RNA815_32959}
4. MligTC455_50387 1074 22.38 Mlig455_018618

Neo: -

Age: logFC(26M/2M)=0.362

Region-enriched R4: 2.247/0.00001
Region-enriched R3: 1.935/0.00000

SLC8B1 4.139 0.869 0.737 - 0.727 0.849 0.957 Mlig455_018618 {REF} {Length: 2020} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=96.0]} {Human: ENSG00000089060, SLC8B1, solute carrier family 8 member B1, [RH, Score=214, Expect=1e-62]} {Mouse: ENSMUSG00000032754, Slc8b1, solute carrier family 8 (sodium/lithium/calcium exchanger), member B1, [RH, Score=220, Expect=4e-65]} {Dmel: FBgn0033324, CG14744, [Score=126, Expect=8e-31]} {Celegans: WBGene00003572, ncx-7, Putative sodium/calcium exchanger 7, [RH, Score=168, Expect=3e-45]} {Smed: dd_Smed_v6_1009_1_1, dd_Smed_v6_1009_1_1, [RH, Score=254, Expect=2e-80]} {RNA1509_17694, RNA1509_27887, RNA1509_3073} {RNA1310_3165.1, RNA1509_17694, RNA1509_27887} {RNA1509_17694, RNA1509_27887, RNA815_1390}
5. MligTC455_16063 772 16.08 Mlig455_026358, Mlig455_052707

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.372

Region-enriched R3: 2.027/0.00000
Region-enriched R4: 1.354/0.01177

SLC39A14 4.11 0.888 0.711 - 0.747 0.788 0.976

Mlig455_026358 {REF} {Length: 2562} {Pfam: ZIP Zinc transporter [PF02535.24, score=177.7]} {Human: ENSG00000104635, SLC39A14, solute carrier family 39 member 14, [Score=187, Expect=4e-53]; ENSG00000196950, SLC39A10, solute carrier family 39 member 10, [Score=179, Expect=3e-48]} {Mouse: ENSMUSG00000022094, Slc39a14, solute carrier family 39 (zinc transporter), member 14, [Score=185, Expect=3e-52]} {Dmel: FBgn0036461, Zip71B, Zinc/iron regulated transporter-related protein 71B, [Score=144, Expect=5e-37]} {Celegans: WBGene00021936, zipt-20, Zrt (ZRT), Irt-(IRT-) like Protein Transporter, [Score=161, Expect=3e-44]} {Smed: dd_Smed_v6_8605_0_1, dd_Smed_v6_8605_0_1, [Score=213, Expect=2e-63]} {RNA1509_35963, RNA1509_39667} {RNA1310_11294, RNA1509_39667} {RNA1509_39667, RNA815_5274}

Mlig455_052707 {REF} {Length: 2641} {Pfam: ZIP Zinc transporter [PF02535.24, score=177.7]} {Human: ENSG00000104635, SLC39A14, solute carrier family 39 member 14, [Score=187, Expect=4e-53]; ENSG00000196950, SLC39A10, solute carrier family 39 member 10, [Score=179, Expect=3e-48]} {Mouse: ENSMUSG00000022094, Slc39a14, solute carrier family 39 (zinc transporter), member 14, [Score=185, Expect=3e-52]} {Dmel: FBgn0036461, Zip71B, Zinc/iron regulated transporter-related protein 71B, [Score=144, Expect=5e-37]} {Celegans: WBGene00021936, zipt-20, Zrt (ZRT), Irt-(IRT-) like Protein Transporter, [Score=161, Expect=3e-44]} {Smed: dd_Smed_v6_8605_0_1, dd_Smed_v6_8605_0_1, [Score=213, Expect=2e-63]} {RNA1509_35963, RNA1509_50293} {RNA1310_11294, RNA1509_35963, RNA1509_50293} {RNA1509_35963, RNA1509_50293, RNA815_5274}
6. MligTC455_17186 498 10.38 Mlig455_066319

Neo: -

Age: -

Region-enriched R4: 3.693/0.00006
Region-enriched R3: 2.735/0.00030
Region-enriched R5: 2.267/0.00198

4.076 0.759 0.810 - 0.845 0.708 0.954 Mlig455_066319 {REF} {Length: 2762} {Pfam: YhhN family [PF07947.16, score=79.2]} {Dmel: FBgn0039681, CG7582, [Score=52.8, Expect=5e-08]} {Smed: dd_Smed_v6_11970_0_1, dd_Smed_v6_11970_0_1, [Score=64.3, Expect=2e-12]} {RNA1509_17539, RNA1509_20437, RNA1509_26581, RNA1509_28364} {RNA1310_11695.1, RNA1509_17539, RNA1509_20437, RNA1509_26581, RNA1509_28364} {RNA1509_17539, RNA1509_20437, RNA1509_26581, RNA1509_28364, RNA815_14610}
7. MligTC455_52436 4103 85.47 Mlig455_036594, Mlig455_057758

Neo: -

Age: -

Region-enriched R3: 2.299/0.00029

FMO4 4.074 0.832 0.710 - 0.852 0.715 0.965

Mlig455_036594 {REF} {Length: 1772} {TRANSSPLICED} {Pfam: Flavin-binding monooxygenase-like [PF00743.21, score=121.5]; Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=43.8]; L-lysine 6-monooxygenase (NADPH-requiring) [PF13434.8, score=21.1]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=18.3]} {Human: ENSG00000076258, FMO4, flavin containing monooxygenase 4, [Score=104, Expect=1e-23]} {Mouse: ENSMUSG00000026560, Fmo9, flavin containing monooxygenase 9, [Score=102, Expect=5e-23]; ENSMUSG00000028088, Fmo5, flavin containing monooxygenase 5, [Score=102, Expect=3e-23]} {Dmel: FBgn0033079, Fmo-2, Flavin-containing monooxygenase 2, [Score=132, Expect=3e-34]} {Celegans: WBGene00016728, C46H11.2, Flavin-containing monooxygenase, [Score=108, Expect=1e-25]} {Smed: dd_Smed_v6_9449_0_1, dd_Smed_v6_9449_0_1, [Score=93.2, Expect=1e-20]} {RNA1509_13926} {RNA1310_13123.1} {RNA815_5157.1}

Mlig455_057758 {REF} {Length: 1759} {TRANSSPLICED} {Pfam: Flavin-binding monooxygenase-like [PF00743.21, score=125.0]; Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=49.5]; FAD-NAD(P)-binding [PF13454.8, score=29.2]; L-lysine 6-monooxygenase (NADPH-requiring) [PF13434.8, score=28.7]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=27.1]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=19.0]; FAD dependent oxidoreductase [PF01266.26, score=18.3]} {Human: ENSG00000076258, FMO4, flavin containing monooxygenase 4, [Score=111, Expect=1e-25]} {Mouse: ENSMUSG00000028088, Fmo5, flavin containing monooxygenase 5, [Score=113, Expect=2e-26]; ENSMUSG00000026560, Fmo9, flavin containing monooxygenase 9, [Score=108, Expect=6e-25]} {Dmel: FBgn0033079, Fmo-2, Flavin-containing monooxygenase 2, [Score=148, Expect=1e-39]} {Celegans: WBGene00016728, C46H11.2, Flavin-containing monooxygenase, [Score=108, Expect=9e-26]} {Smed: dd_Smed_v6_9449_0_1, dd_Smed_v6_9449_0_1, [Score=106, Expect=6e-25]} {RNA1509_13926} {RNA1310_13123.1} {RNA815_5157.1}
8. MligTC455_18651 2559 53.32 Mlig455_067661

Neo: -

Age: -

Region-enriched R3: 1.583/0.04334

4.03 0.706 0.728 - 0.768 0.849 0.979 Mlig455_067661 {REF} {Length: 616} {RNA1509_2812} {RNA1310_3353.1, RNA1509_2812} {RNA1509_2812, RNA815_7653}
9. MligTC455_52041 2170 45.21 Mlig455_029621

Neo: -

Age: logFC(26M/2M)=0.515

Region-enriched R3: 1.780/0.00221
Region-enriched R5: 1.483/0.00437

SCIN 3.908 0.747 0.710 - 0.702 0.791 0.958 Mlig455_029621 {REF} {Length: 1419} {Pfam: Gelsolin repeat [PF00626.24, score=61.4]} {Human: ENSG00000006747, SCIN, scinderin, [Score=78.6, Expect=3e-15]} {Mouse: ENSMUSG00000002565, Scin, scinderin, [Score=82.8, Expect=7e-17]} {Dmel: FBgn0010225, Gel, Gelsolin, [Score=76.6, Expect=7e-15]} {Smed: dd_Smed_v6_1215_0_1, dd_Smed_v6_1215_0_1, [Score=214, Expect=8e-67]} {RNA1509_17911} {RNA1310_15610} {RNA815_7841}
10. MligTC455_44136 8031 167.32 Mlig455_024689, Mlig455_024714

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=0.859

Region-enriched R4: 1.310/0.01340
Region-enriched R3: 1.215/0.02536

FADS2 3.562 - 0.816 - 0.921 0.868 0.957

Mlig455_024689 {REF} {Length: 3861} {TRANSSPLICED} {Pfam: Fatty acid desaturase [PF00487.26, score=116.9]; Cytochrome b5-like Heme/Steroid binding domain [PF00173.30, score=75.0]} {Human: ENSG00000134824, FADS2, fatty acid desaturase 2, [RH, Score=429, Expect=6e-148]; ENSG00000149485, FADS1, fatty acid desaturase 1, [RH, Score=426, Expect=8e-146]} {Mouse: ENSMUSG00000024665, Fads2, fatty acid desaturase 2, [RH, Score=446, Expect=7e-155]} {Dmel: FBgn0029854, CG3566, [Score=56.2, Expect=7e-10]} {Celegans: WBGene00001395, fat-3, Delta(6)-fatty-acid desaturase fat-3, [Score=130, Expect=2e-33]} {Smed: dd_Smed_v6_10869_0_1, dd_Smed_v6_10869_0_1, [Score=328, Expect=3e-109]} {RNA1509_1792, RNA1509_9754} {RNA1310_4526, RNA1509_1792, RNA1509_9754} {RNA1509_1792, RNA1509_9754, RNA815_4497}

Mlig455_024714 {REF} {Length: 5232} {TRANSSPLICED} {Pfam: Fatty acid desaturase [PF00487.26, score=117.3]; Cytochrome b5-like Heme/Steroid binding domain [PF00173.30, score=75.0]} {Human: ENSG00000134824, FADS2, fatty acid desaturase 2, [RH, Score=430, Expect=3e-148]; ENSG00000149485, FADS1, fatty acid desaturase 1, [RH, Score=427, Expect=2e-146]} {Mouse: ENSMUSG00000024665, Fads2, fatty acid desaturase 2, [RH, Score=447, Expect=3e-155]} {Dmel: FBgn0029854, CG3566, [Score=56.2, Expect=7e-10]} {Celegans: WBGene00001395, fat-3, Delta(6)-fatty-acid desaturase fat-3, [Score=130, Expect=2e-33]} {Smed: dd_Smed_v6_10869_0_1, dd_Smed_v6_10869_0_1, [Score=328, Expect=6e-109]} {RNA1509_9754} {RNA1310_4526} {RNA815_4497}
11. MligTC455_24859 5590 116.45 Mlig455_054066, Mlig455_063284

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.306

Region-enriched R3: 2.202/0.00434

3.532 0.890 0.707 - 0.976 - 0.959

Mlig455_054066 {REF} {Length: 1406} {RNA1509_33411, RNA1509_7753} {RNA1310_22791, RNA1509_33411} {RNA1509_33411, RNA815_10514.1}

Mlig455_063284 {REF} {Length: 1414} {Pfam: Multi-glycosylated core protein 24 (MGC-24), sialomucin [PF05283.13, score=46.5]} {Mouse: ENSMUSG00000050912, Tmem123, transmembrane protein 123, [Score=46.6, Expect=2e-06]} {Dmel: FBgn0045823, vsg, visgun, [Score=53.1, Expect=8e-09]} {Smed: dd_Smed_v6_828_0_1, dd_Smed_v6_828_0_1, [RH, Score=53.5, Expect=2e-10]} {RNA1509_7753} {RNA1310_22791} {RNA815_10514.1}
12. MligTC455_47835 636 13.24 Mlig455_043525

Neo: -

Age: -

Region-enriched R3: 2.659/0.00001
Region-enriched R6: 2.142/0.00461
Region-enriched R5: 1.917/0.00072

3.503 0.844 - - 0.883 0.826 0.950 Mlig455_043525 {REF} {Length: 1356} {RNA1509_18381, RNA1509_27428, RNA1509_57910} {RNA1310_28727.1, RNA1509_18381, RNA1509_27428, RNA1509_57910} {RNA1509_18381, RNA1509_27428, RNA1509_57910, RNA815_19848}
13. MligTC455_18868 1328 27.67 Mlig455_067483

Neo: -

Age: -

Region-enriched R3: 1.928/0.00492
Region-enriched R4: 1.837/0.01691
Region-enriched R5: 1.462/0.02245

3.499 0.865 - - 0.719 0.938 0.977 Mlig455_067483 {REF} {Length: 405} {RNA1509_5037} {RNA1310_19379} {RNA815_6182.1}
14. MligTC455_18869 1346 28.04 Mlig455_067491

Neo: -

Age: -

Region-enriched R3: 1.933/0.00397
Region-enriched R4: 1.775/0.01938
Region-enriched R5: 1.440/0.02287

3.499 0.866 - - 0.717 0.940 0.976 Mlig455_067491 {REF} {Length: 2320} {Pfam: NAD dependent epimerase/dehydratase family [PF01370.23, score=72.5]; GDP-mannose 4,6 dehydratase [PF16363.7, score=51.3]; 3-beta hydroxysteroid dehydrogenase/isomerase family [PF01073.21, score=46.4]; Male sterility protein [PF07993.14, score=42.2]; NAD(P)H-binding [PF13460.8, score=39.3]; Polysaccharide biosynthesis protein [PF02719.17, score=30.0]; KR domain [PF08659.12, score=29.5]; NmrA-like family [PF05368.15, score=28.0]; short chain dehydrogenase [PF00106.27, score=19.3]} {Celegans: WBGene00017429, F13D11.4, [RH, Score=213, Expect=4e-66]} {RNA1509_20033, RNA1509_5037} {RNA1310_19379, RNA1509_20033, RNA1509_5037} {RNA1509_20033, RNA1509_5037, RNA815_6182.1}
15. MligTC455_41283 1026 21.38 Mlig455_056291

Neo: -

Age: Down-Up-Up

Region-enriched R3: 2.480/0.00000
Region-enriched R4: 1.642/0.01172
Region-enriched R5: 1.330/0.01324

3.488 0.876 - - 0.829 0.830 0.953 Mlig455_056291 {REF} {Length: 1075} {RNA1509_3034} {RNA1310_55537, RNA1509_3034} {RNA1509_3034, RNA815_28451}
16. MligTC455_50388 1031 21.47 Mlig455_018603, Mlig455_018617

Neo: -

Age: Up-Down-Up

Region-enriched R3: 1.979/0.00000
Region-enriched R4: 1.829/0.00016

SLC8B1 3.459 0.871 - - 0.745 0.877 0.966

Mlig455_018603 {REF} {Length: 3460} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=150.9]} {Human: ENSG00000089060, SLC8B1, solute carrier family 8 member B1, [RH, Score=215, Expect=5e-60]} {Mouse: ENSMUSG00000032754, Slc8b1, solute carrier family 8 (sodium/lithium/calcium exchanger), member B1, [RH, Score=222, Expect=1e-62]} {Dmel: FBgn0033324, CG14744, [Score=127, Expect=4e-30]} {Celegans: WBGene00003572, ncx-7, Putative sodium/calcium exchanger 7, [RH, Score=169, Expect=8e-44]} {Smed: dd_Smed_v6_9904_0_1, dd_Smed_v6_9904_0_1, [RH, Score=359, Expect=5e-110]} {RNA1509_3073} {RNA1310_3165.1, RNA1509_3073} {RNA1509_3073, RNA815_1390}

Mlig455_018617 {REF} {Length: 1059} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=47.3]} {Human: ENSG00000089060, SLC8B1, solute carrier family 8 member B1, [Score=97.1, Expect=4e-25]} {Mouse: ENSMUSG00000032754, Slc8b1, solute carrier family 8 (sodium/lithium/calcium exchanger), member B1, [Score=95.1, Expect=3e-23]} {Dmel: FBgn0033599, CG13223, [Score=60.5, Expect=3e-11]} {Celegans: WBGene00003572, ncx-7, Putative sodium/calcium exchanger 7, [Score=68.9, Expect=3e-14]} {Smed: dd_Smed_v6_20334_0_5, dd_Smed_v6_20334_0_5, [Score=114, Expect=6e-33]} {RNA1509_3073} {RNA1310_3165.1} {RNA815_1823}
17. MligTC455_44530 352 7.33 Mlig455_038035

Neo: -

Age: Down-Up-Up

Region-enriched R3: 1.753/0.00110
Region-enriched R4: 1.598/0.01280
Region-enriched R5: 1.140/0.02561

3.458 - 0.786 - 0.869 0.815 0.988 Mlig455_038035 {REF} {Length: 1762} {Pfam: Universal stress protein family [PF00582.28, score=87.1]} {Smed: dd_Smed_v6_3388_0_1, dd_Smed_v6_3388_0_1, [Score=82.0, Expect=3e-20]} {RNA1509_59467} {RNA1310_35905, RNA1509_59467} {RNA1509_59467, RNA815_18113}
18. MligTC455_16064 205 4.27 Mlig455_026327

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.743

Region-enriched R3: 2.239/0.00850

SLC39A14 3.448 0.751 - - 0.916 0.820 0.961 Mlig455_026327 {REF} {Length: 2551} {Pfam: ZIP Zinc transporter [PF02535.24, score=177.4]} {Human: ENSG00000104635, SLC39A14, solute carrier family 39 member 14, [Score=187, Expect=6e-53]; ENSG00000196950, SLC39A10, solute carrier family 39 member 10, [Score=179, Expect=2e-48]} {Mouse: ENSMUSG00000022094, Slc39a14, solute carrier family 39 (zinc transporter), member 14, [Score=184, Expect=4e-52]} {Dmel: FBgn0036461, Zip71B, Zinc/iron regulated transporter-related protein 71B, [Score=144, Expect=3e-37]} {Celegans: WBGene00021936, zipt-20, Zrt (ZRT), Irt-(IRT-) like Protein Transporter, [Score=160, Expect=3e-44]} {Smed: dd_Smed_v6_8605_0_1, dd_Smed_v6_8605_0_1, [Score=213, Expect=2e-63]} {RNA1509_16476} {RNA1310_11294, RNA1509_16476} {RNA1509_16476, RNA815_5274}
19. MligTC455_34295 1251 26.06 Mlig455_039417

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-1.176

Region-enriched R3: 2.357/0.00048
Region-enriched R4: 1.872/0.01857

3.443 0.746 - - 0.826 0.921 0.950 Mlig455_039417 {REF} {Length: 666} {RNA1509_26409, RNA1509_26731, RNA1509_44065, RNA1509_51827} {RNA1310_54443, RNA1509_26409, RNA1509_26731, RNA1509_44065, RNA1509_51827} {RNA1509_26409, RNA1509_26731, RNA1509_44065, RNA1509_51827, RNA815_29054}
20. MligTC455_15686 5588 116.41 Mlig455_011058

Neo: -

Age: -

Region-enriched R3: 1.651/0.01200
Region-enriched R5: 1.436/0.01547

CRABP2 3.407 0.701 - - 0.987 0.783 0.936 Mlig455_011058 {REF} {Length: 857} {Pfam: Lipocalin / cytosolic fatty-acid binding protein family [PF00061.25, score=54.9]; Lipocalin / cytosolic fatty-acid binding protein family [PF14651.8, score=29.1]} {Human: ENSG00000143320, CRABP2, cellular retinoic acid binding protein 2, [Score=95.5, Expect=1e-25]; ENSG00000170323, FABP4, fatty acid binding protein 4, [Score=91.7, Expect=3e-24]; ENSG00000121769, FABP3, fatty acid binding protein 3, [Score=91.3, Expect=4e-24]} {Mouse: ENSMUSG00000004885, Crabp2, cellular retinoic acid binding protein II, [Score=95.9, Expect=5e-26]; ENSMUSG00000027533, Fabp5, fatty acid binding protein 5, epidermal, [Score=93.2, Expect=5e-25]; ENSMUSG00000028773, Fabp3, fatty acid binding protein 3, muscle and heart, [Score=92.4, Expect=1e-24]} {Dmel: FBgn0037913, fabp, fatty acid binding protein, [Score=76.6, Expect=1e-18]} {Celegans: WBGene00002257, lbp-5, Fatty acid-binding protein homolog 5, [Score=100, Expect=6e-28]} {Smed: dd_Smed_v6_271_0_1, dd_Smed_v6_271_0_1, [RH, Score=102, Expect=6e-29]} {RNA1509_23333, RNA1509_23783, RNA1509_29966, RNA1509_3321, RNA1509_6404} {RNA1310_38135.2, RNA1509_23333, RNA1509_23783, RNA1509_29966, RNA1509_3321, RNA1509_6404} {RNA1509_23333, RNA1509_23783, RNA1509_29966, RNA1509_3321, RNA1509_6404, RNA815_30164}
21. MligTC455_22268 6636 138.25 Mlig455_011760

Neo: -

Age: logFC(26M/2M)=-0.323

Region-enriched R3: 1.908/0.00000
Region-enriched R6: 1.283/0.01830
Region-enriched R5: 1.133/0.00963

3.394 0.815 - - 0.755 0.872 0.952 Mlig455_011760 {REF} {Length: 2561} {RNA1509_1433} {RNA1310_8428, RNA1509_1433} {RNA1509_1433, RNA815_2971}
22. MligTC455_39169 881 18.35 Mlig455_063890

Neo: -

Age: -

Region-enriched R3: 3.017/0.00000

ALDH2 3.388 0.913 0.712 - - 0.811 0.952 Mlig455_063890 {REF} {Length: 2688} {Pfam: Aldehyde dehydrogenase family [PF00171.24, score=591.3]} {Human: ENSG00000111275, ALDH2, aldehyde dehydrogenase 2 family member, [RH, Score=777, Expect=0.0]; ENSG00000137124, ALDH1B1, aldehyde dehydrogenase 1 family member B1, [RH, Score=753, Expect=0.0]} {Mouse: ENSMUSG00000029455, Aldh2, aldehyde dehydrogenase 2, mitochondrial, [RH, Score=768, Expect=0.0]; ENSMUSG00000035561, Aldh1b1, aldehyde dehydrogenase 1 family, member B1, [RH, Score=749, Expect=0.0]} {Dmel: FBgn0012036, Aldh, Aldehyde dehydrogenase, [RH, Score=718, Expect=0.0]} {Celegans: WBGene00000107, alh-1, ALdehyde deHydrogenase, [RH, Score=725, Expect=0.0]} {Smed: dd_Smed_v6_1339_0_1, dd_Smed_v6_1339_0_1, [RH, Score=726, Expect=0.0]} {RNA1509_1186, RNA1509_20297} {RNA1310_3799.1, RNA1509_20297} {RNA1509_20297, RNA815_1286.1}
23. MligTC455_19080 969 20.19 Mlig455_033341

Neo: -

Age: Up-Down-Down

Region-enriched R5: 1.378/0.02877

3.369 0.853 0.707 - - 0.853 0.956 Mlig455_033341 {REF} {Length: 1009} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_41133} {RNA1310_2059.1} {RNA815_20560.2}
24. MligTC455_16062 635 13.22 Mlig455_026314

Neo: -

Age: logFC(26M/2M)=-0.923

Region-enriched R3: 2.095/0.00000
Region-enriched R4: 1.472/0.00808

SLC39A14 3.368 0.899 - - 0.795 0.702 0.972 Mlig455_026314 {REF} {Length: 5567} {Pfam: ZIP Zinc transporter [PF02535.24, score=127.9]} {Human: ENSG00000104635, SLC39A14, solute carrier family 39 member 14, [Score=138, Expect=1e-36]} {Mouse: ENSMUSG00000022094, Slc39a14, solute carrier family 39 (zinc transporter), member 14, [Score=135, Expect=5e-36]} {Dmel: FBgn0036461, Zip71B, Zinc/iron regulated transporter-related protein 71B, [Score=95.5, Expect=1e-21]} {Celegans: WBGene00021936, zipt-20, Zrt (ZRT), Irt-(IRT-) like Protein Transporter, [Score=114, Expect=8e-29]} {Smed: dd_Smed_v6_8605_0_1, dd_Smed_v6_8605_0_1, [Score=162, Expect=2e-46]} {RNA1509_16476} {RNA1310_12919} {RNA815_5274}
25. MligTC455_48796 3932 81.93 Mlig455_010032, Mlig455_063287

Neo: -

Age: -

Region-enriched R3: 1.371/0.00023

3.365 0.814 - - 0.863 0.720 0.968

Mlig455_010032 {REF} {Length: 3305} {TRANSSPLICED} {Dmel: FBgn0051195, CG31195, [RH, Score=445, Expect=3e-143]} {Smed: dd_Smed_v6_2407_0_1, dd_Smed_v6_2407_0_1, [RH, Score=727, Expect=0.0]} {RNA1509_1610, RNA1509_26475} {RNA1310_2842, RNA1509_1610, RNA1509_26475} {RNA1509_1610, RNA1509_26475, RNA815_1220.1}

Mlig455_063287 {REF} {Length: 3306} {TRANSSPLICED} {Dmel: FBgn0051195, CG31195, [RH, Score=445, Expect=4e-143]} {Smed: dd_Smed_v6_2407_0_1, dd_Smed_v6_2407_0_1, [RH, Score=726, Expect=0.0]} {RNA1509_1610} {RNA1310_2842} {RNA815_1220.1}
26. MligTC455_18723 1597 33.27 Mlig455_004384

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.781

Region-enriched R3: 2.164/0.00079
Region-enriched R4: 1.576/0.04930
Region-enriched R5: 1.329/0.03977

SLC3A1 3.358 0.896 - - 0.739 0.762 0.961 Mlig455_004384 {REF} {Length: 2040} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=310.6]} {Human: ENSG00000138079, SLC3A1, solute carrier family 3 member 1, [RH, Score=371, Expect=2e-119]} {Mouse: ENSMUSG00000024131, Slc3a1, solute carrier family 3, member 1, [RH, Score=372, Expect=4e-120]} {Dmel: FBgn0002570, Mal-A1, Maltase A1, [RH, Score=384, Expect=2e-126]} {Celegans: WBGene00000224, atgp-1, Amino acid Transporter GlycoProtein subunit, [RH, Score=146, Expect=3e-37]} {Smed: dd_Smed_v6_2113_0_1, dd_Smed_v6_2113_0_1, [Score=67.8, Expect=8e-12]} {RNA1509_19345} {RNA1310_12682.1} {RNA815_15968}
27. MligTC455_18724 1612 33.59 Mlig455_037198

Neo: -

Age: -

Region-enriched R3: 2.022/0.00141

SLC3A1 3.355 0.893 - - 0.732 0.768 0.962 Mlig455_037198 {REF} {Length: 2052} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=311.9]} {Human: ENSG00000138079, SLC3A1, solute carrier family 3 member 1, [RH, Score=373, Expect=2e-120]} {Mouse: ENSMUSG00000024131, Slc3a1, solute carrier family 3, member 1, [RH, Score=374, Expect=5e-121]} {Dmel: FBgn0002570, Mal-A1, Maltase A1, [RH, Score=385, Expect=1e-126]} {Celegans: WBGene00000225, atgp-2, Amino acid Transporter GlycoProtein subunit, [RH, Score=147, Expect=2e-37]} {Smed: dd_Smed_v6_2113_0_1, dd_Smed_v6_2113_0_1, [Score=67.8, Expect=9e-12]} {RNA1509_14094, RNA1509_15182, RNA1509_19345} {RNA1310_12682.1, RNA1509_14094, RNA1509_15182, RNA1509_19345} {RNA1509_14094, RNA1509_15182, RNA1509_19345, RNA815_15968}
28. MligTC455_41503 3372 70.25 Mlig455_015421

Neo: -

Age: -

Region-enriched R3: 1.663/0.00123

3.326 0.778 - - 0.708 0.890 0.950 Mlig455_015421 {REF} {Length: 3377} {Pfam: Fasciclin domain [PF02469.24, score=41.0]} {Dmel: FBgn0032638, SPH93, Serine protease homolog 93, [Score=61.6, Expect=2e-09]} {RNA1509_26815, RNA1509_27548, RNA1509_56488} {RNA1310_8987, RNA1509_26815, RNA1509_27548, RNA1509_56488} {RNA1509_26815, RNA1509_27548, RNA1509_56488, RNA815_3084.1}
29. MligTC455_35962 331 6.9 Mlig455_022661

Neo: -

Age: -

3.315 0.761 0.761 - 0.836 - 0.957 Mlig455_022661 {REF} {Length: 220} {NoTransDecoderORF} {RNA1509_19906} {RNA1310_19437} {RNA815_21043}
30. MligTC455_49659 4741 98.77 Mlig455_011512, Mlig455_050003

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.314

Region-enriched R3: 1.923/0.00380

3.311 0.842 - - 0.778 0.723 0.968

Mlig455_011512 {REF} {Length: 2299} {RNA1509_3964} {RNA1310_32368} {RNA815_14237.1}

Mlig455_050003 {REF} {Length: 1812} {RNA1509_3964} {RNA1310_32368} {RNA815_14237.1}
31. MligTC455_27981 1573 32.77 Mlig455_014661

Neo: -

Age: -

Region-enriched R3: 1.975/0.00314

SLC9A3R2 3.303 0.773 0.797 - 0.983 - 0.750 Mlig455_014661 {REF} {Length: 2473} {Pfam: PDZ domain [PF00595.26, score=41.4]; PDZ domain [PF17820.3, score=26.4]; PDZ domain [PF13180.8, score=23.8]} {Human: ENSG00000065054, SLC9A3R2, SLC9A3 regulator 2, [RH, Score=97.4, Expect=7e-23]} {Mouse: ENSMUSG00000002504, Slc9a3r2, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2, [RH, Score=96.7, Expect=1e-22]; ENSMUSG00000020733, Slc9a3r1, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1, [RH, Score=95.9, Expect=3e-22]} {Dmel: FBgn0010620, CG10939, [Score=89.7, Expect=2e-20]} {Celegans: WBGene00006438, nrfl-1, NHERF (Mammalian Na/H Exchange Regulatory Factor) Like, [Score=92.4, Expect=5e-21]} {Smed: dd_Smed_v6_3039_0_1, dd_Smed_v6_3039_0_1, [Score=110, Expect=3e-29]} {RNA1509_39084} {RNA1310_17362} {RNA815_22754.1}
32. MligTC455_27756 2766 57.63 Mlig455_036299, Mlig455_036313

Neo: -

Age: logFC(26M/2M)=0.266

Region-enriched R3: 1.773/0.00001
Region-enriched R4: 1.368/0.00784

AF241726.2, TSPAN7 3.293 0.742 - - 0.870 0.731 0.950

Mlig455_036299 {REF} {Length: 1664} {Pfam: Tetraspanin family [PF00335.22, score=86.9]} {Human: ENSG00000250349, AF241726.2, novel proline rich Gla (G-carboxyglutamic acid) 1 (PRRG1) and tetraspanin 7 (TSPAN7) protein, [Score=63.2, Expect=7e-11]; ENSG00000156298, TSPAN7, tetraspanin 7, [Score=62.8, Expect=8e-11]} {Mouse: ENSMUSG00000058254, Tspan7, tetraspanin 7, [Score=61.6, Expect=1e-10]; ENSMUSG00000067377, Tspan6, tetraspanin 6, [Score=59.3, Expect=7e-10]} {Celegans: WBGene00023491, tsp-21, Tetraspanin, [Score=50.4, Expect=5e-07]} {Smed: dd_Smed_v6_854_1_1, dd_Smed_v6_854_1_1, [Score=109, Expect=3e-28]} {RNA1509_20407} {RNA1310_5241, RNA1509_20407} {RNA1509_20407, RNA815_7978}

Mlig455_036313 {REF} {Length: 3246} {Pfam: Tetraspanin family [PF00335.22, score=139.9]} {Human: ENSG00000156298, TSPAN7, tetraspanin 7, [Score=62.4, Expect=6e-10]; ENSG00000250349, AF241726.2, novel proline rich Gla (G-carboxyglutamic acid) 1 (PRRG1) and tetraspanin 7 (TSPAN7) protein, [Score=60.5, Expect=3e-09]} {Mouse: ENSMUSG00000058254, Tspan7, tetraspanin 7, [Score=61.6, Expect=6e-10]} {Smed: dd_Smed_v6_854_1_1, dd_Smed_v6_854_1_1, [Score=107, Expect=9e-26]} {RNA1509_20407} {RNA1310_5241} {RNA815_7978}
33. MligTC455_25126 312 6.5 Mlig455_008236

Neo: -

Age: Down-Down-Up

Region-enriched R4: 2.580/0.00515
Region-enriched R3: 2.489/0.00779
Region-enriched R5: 2.089/0.01974

3.291 0.711 - - 0.955 0.819 0.806 Mlig455_008236 {REF} {Length: 2061} {TRANSSPLICED} {RNA1509_16045, RNA1509_29412} {RNA1310_35530.2, RNA1509_16045, RNA1509_29412} {RNA1509_16045, RNA1509_29412, RNA815_17294.1}
34. MligTC455_21475 15839 329.98 Mlig455_064237

Neo: -

Age: logFC(26M/2M)=0.290

Region-enriched R3: 2.133/0.00005

CTSV 3.278 0.797 - - 0.701 0.826 0.954 Mlig455_064237 {REF} {Length: 2670} {Pfam: Papain family cysteine protease [PF00112.25, score=291.7]; Cathepsin propeptide inhibitor domain (I29) [PF08246.14, score=54.9]; Peptidase C1-like family [PF03051.17, score=27.5]} {Human: ENSG00000136943, CTSV, cathepsin V, [RH, Score=358, Expect=3e-123]; ENSG00000135047, CTSL, cathepsin L, [RH, Score=356, Expect=2e-122]} {Mouse: ENSMUSG00000021477, Ctsl, cathepsin L, [RH, Score=348, Expect=9e-120]; ENSMUSG00000042243, BC051665, cDNA sequence BC051665, [RH, Score=335, Expect=1e-114]; ENSMUSG00000056728, Ctsll3, cathepsin L-like 3, [RH, Score=333, Expect=2e-113]} {Dmel: FBgn0013770, Cp1, Cysteine proteinase-1, [Score=359, Expect=6e-124]} {Celegans: WBGene00000776, cpl-1, CathePsin L family, [RH, Score=336, Expect=6e-115]} {Smed: dd_Smed_v6_48_0_1, dd_Smed_v6_48_0_1, [RH, Score=428, Expect=2e-151]} {RNA1509_124, RNA1509_29064, RNA1509_51476, RNA1509_81} {RNA1310_16613, RNA1509_29064, RNA1509_51476, RNA1509_81} {RNA1509_29064, RNA1509_51476, RNA1509_81, RNA815_7527}
35. MligTC455_47128 122 2.54 Mlig455_017313

Neo: -

Age: Down-Up-Down

Region-enriched R4: 4.406/0.01334

3.27 0.813 - 0.779 0.711 - 0.967 Mlig455_017313 {REF} {Length: 1377} {Pfam: Syntaxin 6, N-terminal [PF09177.13, score=37.3]} {RNA1509_23730} {RNA1310_20266} {RNA815_12077}
36. MligTC455_53877 1399 29.15 Mlig455_016664

Neo: -

Age: logFC(26M/2M)=0.488

Region-enriched R3: 1.947/0.00083
Region-enriched R4: 1.666/0.01644

CLCA1 3.235 0.823 0.716 - - 0.739 0.957 Mlig455_016664 {REF} {Length: 4164} {Pfam: Calcium-activated chloride channel N terminal [PF08434.13, score=169.0]} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [Score=166, Expect=4e-43]} {Mouse: ENSMUSG00000028255, Clca1, chloride channel accessory 1, [Score=163, Expect=2e-42]} {RNA1509_1021} {RNA1310_5461.1} {RNA815_1665}
37. MligTC455_24112 7326 152.63 Mlig455_006637, Mlig455_070643

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.380

CYP2D6, CYP2U1 3.223 0.762 - - 0.736 0.767 0.958

Mlig455_006637 {REF} {Length: 1777} {Pfam: Cytochrome P450 [PF00067.24, score=343.6]} {Human: ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=263, Expect=7e-81]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [RH, Score=263, Expect=2e-81]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [RH, Score=260, Expect=2e-80]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [RH, Score=259, Expect=4e-80]; ENSG00000275211, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=2e-79]; ENSG00000283284, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=1e-79]; ENSG00000100197, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=3e-79]; ENSG00000280905, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]; ENSG00000272532, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]; ENSG00000272000, AC236040.1, cytochrome P450 family 2 subfamily D member 6 pseudogene, [RH, Score=257, Expect=4e-79]; ENSG00000282966, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]} {Mouse: ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=285, Expect=3e-90]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [RH, Score=283, Expect=1e-89]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=278, Expect=2e-87]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=273, Expect=2e-85]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=271, Expect=8e-85]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=271, Expect=1e-84]} {Dmel: FBgn0001992, Cyp303a1, [RH, Score=207, Expect=1e-60]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [RH, Score=292, Expect=3e-93]} {RNA1509_10420} {RNA1310_15091.1} {RNA815_4606.2}

Mlig455_070643 {REF} {Length: 2371} {Pfam: Cytochrome P450 [PF00067.24, score=337.1]} {Human: ENSG00000283284, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=261, Expect=1e-80]; ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=260, Expect=7e-80]; ENSG00000275211, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=260, Expect=2e-80]; ENSG00000282966, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000272000, AC236040.1, cytochrome P450 family 2 subfamily D member 6 pseudogene, [RH, Score=259, Expect=3e-80]; ENSG00000272532, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000280905, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000100197, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [RH, Score=256, Expect=6e-79]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [RH, Score=254, Expect=3e-78]} {Mouse: ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=280, Expect=2e-88]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [RH, Score=279, Expect=7e-88]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=275, Expect=3e-86]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=268, Expect=1e-83]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=268, Expect=1e-83]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=266, Expect=7e-83]} {Dmel: FBgn0001992, Cyp303a1, [RH, Score=201, Expect=4e-58]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [RH, Score=288, Expect=2e-91]} {RNA1509_10420, RNA1509_36519} {RNA1310_15091.1, RNA1509_10420, RNA1509_36519} {RNA1509_10420, RNA1509_36519, RNA815_4606.2}
38. MligTC455_53238 596 12.41 Mlig455_035167

Neo: -

Age: Up-Down-Up

Region-enriched R4: 1.901/0.01128

3.22 0.790 - - 0.753 0.721 0.956 Mlig455_035167 {REF} {Length: 2562} {Pfam: ADP-ribosyl cyclase [PF02267.19, score=167.1]} {RNA1509_44710} {RNA1310_17806, RNA1509_44710} {RNA1509_44710, RNA815_24749}
39. MligTC455_52040 2198 45.8 Mlig455_029597

Neo: Germline

Age: logFC(26M/2M)=0.256

Region-enriched R3: 1.723/0.00072
Region-enriched R5: 1.481/0.00114

VIL1 3.216 0.744 0.711 - - 0.803 0.958 Mlig455_029597 {REF} {Length: 2577} {Pfam: Gelsolin repeat [PF00626.24, score=113.7]} {Human: ENSG00000127831, VIL1, villin 1, [Score=182, Expect=5e-53]; ENSG00000148180, GSN, gelsolin, [Score=179, Expect=1e-49]; ENSG00000135407, AVIL, advillin, [Score=174, Expect=1e-47]} {Mouse: ENSMUSG00000026879, Gsn, gelsolin, [Score=185, Expect=7e-52]; ENSMUSG00000026175, Vil1, villin 1, [Score=182, Expect=1e-50]} {Dmel: FBgn0010225, Gel, Gelsolin, [Score=194, Expect=3e-55]} {Celegans: WBGene00010593, gsnl-1, Gelsolin-like protein 1, [Score=164, Expect=4e-46]} {Smed: dd_Smed_v6_1215_0_1, dd_Smed_v6_1215_0_1, [RH, Score=403, Expect=3e-140]} {RNA1509_12411, RNA1509_17911, RNA1509_2858, RNA1509_30271, RNA1509_44412, RNA1509_44633} {RNA1310_15610, RNA1509_12411, RNA1509_17911, RNA1509_2858, RNA1509_30271, RNA1509_44412, RNA1509_44633} {RNA1509_12411, RNA1509_17911, RNA1509_2858, RNA1509_30271, RNA1509_44412, RNA1509_44633, RNA815_7841}
40. MligTC455_35633 4966 103.45 Mlig455_048471

Neo: -

Age: -

Region-enriched R4: 1.579/0.00682
Region-enriched R3: 1.493/0.00762

DHDH 3.178 0.754 - - 0.761 0.712 0.951 Mlig455_048471 {REF} {Length: 1491} {Pfam: Oxidoreductase family, NAD-binding Rossmann fold [PF01408.24, score=87.6]; Oxidoreductase family, C-terminal alpha/beta domain [PF02894.19, score=32.8]; Homoserine dehydrogenase, NAD binding domain [PF03447.18, score=19.9]} {Human: ENSG00000104808, DHDH, dihydrodiol dehydrogenase, [RH, Score=246, Expect=3e-79]} {Mouse: ENSMUSG00000011382, Dhdh, dihydrodiol dehydrogenase (dimeric), [RH, Score=248, Expect=4e-80]} {Dmel: FBgn0031418, CG3609, [RH, Score=231, Expect=1e-73]} {Smed: dd_Smed_v6_7643_0_1, dd_Smed_v6_7643_0_1, [RH, Score=213, Expect=9e-67]} {RNA1509_1049, RNA1509_4889, RNA1509_8979} {RNA1310_24236, RNA1509_1049, RNA1509_4889, RNA1509_8979} {RNA1509_1049, RNA1509_4889, RNA1509_8979, RNA815_11111.1}
41. MligTC455_37239 1846 38.46 Mlig455_060082

Neo: -

Age: -

Region-enriched R3: 1.562/0.04763
Region-enriched R5: 1.292/0.04648

PANK4 3.159 0.733 0.718 - 0.719 - 0.989 Mlig455_060082 {REF} {Length: 1532} {Pfam: Fumble [PF03630.16, score=120.5]} {Human: ENSG00000273494, PANK4, pantothenate kinase 4, [Score=106, Expect=2e-24]; ENSG00000157881, PANK4, pantothenate kinase 4, [Score=106, Expect=2e-24]} {Mouse: ENSMUSG00000029056, Pank4, pantothenate kinase 4, [Score=97.4, Expect=1e-21]} {Dmel: FBgn0011205, fbl, fumble, [Score=66.2, Expect=7e-12]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [Score=170, Expect=1e-49]} {RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233} {RNA1310_20224, RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233} {RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233, RNA815_7673}
42. MligTC455_16257 1877 39.1 Mlig455_026808, Mlig455_030881

Neo: -

Age: Down-Down-Up

Region-enriched R4: 2.209/0.00209
Region-enriched R3: 1.663/0.01717
Region-enriched R5: 1.364/0.02606

STOM 2.77 - - - 0.919 0.893 0.958

Mlig455_026808 {REF} {Length: 1301} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=20.6]} {Human: ENSG00000148175, STOM, stomatin, [Score=123, Expect=2e-35]; ENSG00000133115, STOML3, stomatin like 3, [Score=118, Expect=1e-33]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [Score=123, Expect=2e-35]; ENSMUSG00000027744, Stoml3, stomatin (Epb7.2)-like 3, [Score=120, Expect=2e-34]; ENSMUSG00000026602, Nphs2, nephrosis 2, podocin, [Score=117, Expect=2e-32]} {Dmel: FBgn0260657, CG42540, [Score=126, Expect=5e-36]} {Celegans: WBGene00006068, sto-6, STOmatin, [Score=140, Expect=1e-42]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [Score=148, Expect=1e-45]} {RNA1509_6816} {RNA1310_26895} {RNA815_11983}

Mlig455_030881 {REF} {Length: 1405} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=110.3]; SPFH domain-Band 7 family [PF13421.8, score=20.7]} {Human: ENSG00000148175, STOM, stomatin, [Score=335, Expect=3e-115]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [Score=323, Expect=5e-111]} {Dmel: FBgn0260657, CG42540, [Score=323, Expect=2e-109]} {Celegans: WBGene00003166, mec-2, Mechanosensory protein 2, [Score=335, Expect=4e-114]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [Score=362, Expect=1e-126]} {RNA1509_6816} {RNA1310_26895, RNA1509_6816} {RNA1509_6816, RNA815_11983}
43. MligTC455_24083 6997 145.77 Mlig455_007319

Neo: -

Age: -

Region-enriched R3: 2.037/0.00010
Region-enriched R5: 1.165/0.04106

ACHE 2.712 0.876 - - - 0.874 0.962 Mlig455_007319 {REF} {Length: 2399} {Pfam: Carboxylesterase family [PF00135.30, score=344.4]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=233, Expect=9e-68]} {Mouse: ENSMUSG00000023328, Ache, acetylcholinesterase, [Score=225, Expect=3e-65]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=183, Expect=6e-50]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=228, Expect=1e-66]} {Smed: dd_Smed_v6_4800_0_1, dd_Smed_v6_4800_0_1, [Score=184, Expect=4e-50]} {RNA1509_195, RNA1509_4270, RNA1509_51012} {RNA1310_9229, RNA1509_4270, RNA1509_51012} {RNA1509_4270, RNA1509_51012, RNA815_3141.1}
44. MligTC455_18366 547 11.39 Mlig455_026325

Neo: -

Age: Down-Down-Up

Region-enriched R4: 3.044/0.02719
Region-enriched R3: 2.953/0.02551

IFI30 2.686 - 0.774 - - 0.945 0.967 Mlig455_026325 {REF} {Length: 1133} {Pfam: Gamma interferon inducible lysosomal thiol reductase (GILT) [PF03227.18, score=101.0]} {Human: ENSG00000216490, IFI30, IFI30, lysosomal thiol reductase, [RH, Score=143, Expect=1e-41]} {Mouse: ENSMUSG00000110777, Ifi30, interferon gamma inducible protein 30, [RH, Score=118, Expect=4e-32]} {Dmel: FBgn0038149, GILT1, Gamma-interferon-inducible lysosomal thiol reductase 1, [Score=95.5, Expect=1e-23]} {Celegans: WBGene00009514, F37H8.5, GILT-like protein F37H8.5, [Score=100, Expect=3e-25]} {Smed: dd_Smed_v6_2024_0_1, dd_Smed_v6_2024_0_1, [Score=104, Expect=8e-28]} {RNA1509_51694} {RNA1310_32351.1} {RNA815_17592}
45. MligTC455_27869 8765 182.6 Mlig455_051857, Mlig455_051868, Mlig455_051893

Neo: -

Age: Down-Down-Up

Region-enriched R3: 2.214/0.00040
Region-enriched R5: 1.603/0.01133

ANPEP 2.67 0.839 - - 0.978 0.853 -

Mlig455_051857 {REF} {Length: 3680} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=260.1]; Peptidase family M1 domain [PF01433.22, score=238.0]; Peptidase M1 N-terminal domain [PF17900.3, score=137.9]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=560, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [RH, Score=546, Expect=6e-179]} {Dmel: FBgn0039640, CG14516, [RH, Score=536, Expect=1e-174]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=405, Expect=2e-125]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=599, Expect=0.0]} {RNA1509_5196} {RNA1310_2955.1} {RNA815_759.2}

Mlig455_051868 {REF} {Length: 4344} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=259.5]; Peptidase family M1 domain [PF01433.22, score=234.1]; Peptidase M1 N-terminal domain [PF17900.3, score=137.9]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=552, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [Score=542, Expect=4e-177]} {Dmel: FBgn0039640, CG14516, [RH, Score=529, Expect=7e-172]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=406, Expect=1e-125]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=595, Expect=0.0]} {RNA1509_5196} {RNA1310_2955.1} {RNA815_759.2}

Mlig455_051893 {REF} {Length: 4373} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=260.1]; Peptidase family M1 domain [PF01433.22, score=236.2]; Peptidase M1 N-terminal domain [PF17900.3, score=137.9]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=558, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [RH, Score=545, Expect=3e-178]} {Dmel: FBgn0039640, CG14516, [RH, Score=533, Expect=2e-173]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=405, Expect=2e-125]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=596, Expect=0.0]} {RNA1509_5196} {RNA1310_2955.1} {RNA815_759.2}
46. MligTC455_19589 1267 26.39 Mlig455_019782, Mlig455_019805

Neo: -

Age: Down-Down-Up

Region-enriched R3: 2.513/0.00008
Region-enriched R4: 2.414/0.00063
Region-enriched R5: 2.371/0.00008
Region-enriched R6: 1.844/0.03273

2.669 0.804 - - - 0.893 0.972

Mlig455_019782 {REF} {Length: 858} {RNA1509_20360} {RNA1310_37068} {RNA815_23648}

Mlig455_019805 {REF} {Length: 869} {RNA1509_20360, RNA1509_54648} {RNA1310_37068, RNA1509_54648} {RNA1509_54648, RNA815_23648}
47. MligTC455_47879 2386 49.71 Mlig455_031211

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.530

2.667 - 0.760 - 0.987 - 0.920 Mlig455_031211 {REF} {Length: 989} {Pfam: Wnt and FGF inhibitory regulator [PF13908.8, score=20.1]} {RNA1509_49697, RNA1509_6639} {RNA1310_43777, RNA1509_49697, RNA1509_6639} {RNA1509_49697, RNA1509_6639, RNA815_26112.1}
48. MligTC455_22151 1286 26.78 Mlig455_054961

Neo: -

Age: Down-Up-Down

Region-enriched R4: 2.174/0.00000
Region-enriched R3: 1.898/0.00000
Region-enriched R5: 1.123/0.00549

XDH 2.648 0.815 - - - 0.866 0.967 Mlig455_054961 {REF} {Length: 8931} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=746.5]; [2Fe-2S] binding domain [PF01799.22, score=187.9]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=151.5]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=115.0]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=110.3]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=28.4]} {Human: ENSG00000158125, XDH, xanthine dehydrogenase, [Score=490, Expect=1e-144]; ENSG00000138356, AOX1, aldehyde oxidase 1, [Score=472, Expect=2e-138]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=496, Expect=5e-147]; ENSMUSG00000038242, Aox4, aldehyde oxidase 4, [Score=472, Expect=7e-139]} {Dmel: FBgn0038349, AOX3, Aldehyde oxidase 3, [RH, Score=658, Expect=0.0]} {Celegans: WBGene00010083, xhd-1, [Score=501, Expect=1e-148]} {RNA1509_48253} {RNA1310_3150.1} {RNA815_224.3}
49. MligTC455_51957 427 8.9 Mlig455_001616

Neo: -

Age: logFC(26M/2M)=0.792

LCK 2.615 - 0.771 - 0.889 - 0.955 Mlig455_001616 {REF} {Length: 2834} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=195.1]; Protein kinase domain [PF00069.27, score=130.1]; Variant SH3 domain [PF14604.8, score=43.0]; SH2 domain [PF00017.26, score=42.8]; Variant SH3 domain [PF07653.19, score=36.6]; SH3 domain [PF00018.30, score=35.8]; ABC1 atypical kinase-like domain [PF03109.18, score=28.0]} {Human: ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=251, Expect=7e-78]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=250, Expect=5e-77]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=241, Expect=1e-73]} {Mouse: ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=255, Expect=4e-79]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=243, Expect=7e-75]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=239, Expect=4e-73]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=213, Expect=5e-64]} {Smed: dd_Smed_v6_3363_0_2, dd_Smed_v6_3363_0_2, [Score=304, Expect=6e-99]} {RNA1509_10615, RNA1509_47356} {RNA1310_9006.1, RNA1509_47356} {RNA1509_47356, RNA815_3005.1}
50. MligTC455_34695 309 6.44 Mlig455_018530

Neo: -

Age: -

Region-enriched R3: 4.486/0.00000
Region-enriched R5: 3.375/0.00129

CYP2C8 2.613 - 0.822 - 0.960 - 0.831 Mlig455_018530 {REF} {Length: 2705} {Pfam: Cytochrome P450 [PF00067.24, score=331.1]} {Human: ENSG00000138115, CYP2C8, cytochrome P450 family 2 subfamily C member 8, [RH, Score=285, Expect=6e-90]; ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=271, Expect=1e-83]} {Mouse: ENSMUSG00000074254, Cyp2a4, cytochrome P450, family 2, subfamily a, polypeptide 4, [RH, Score=276, Expect=1e-86]; ENSMUSG00000032808, Cyp2c38, cytochrome P450, family 2, subfamily c, polypeptide 38, [RH, Score=276, Expect=1e-86]; ENSMUSG00000005547, Cyp2a5, cytochrome P450, family 2, subfamily a, polypeptide 5, [RH, Score=273, Expect=4e-85]; ENSMUSG00000116063, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [RH, Score=270, Expect=1e-83]; ENSMUSG00000027983, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [RH, Score=270, Expect=1e-83]; ENSMUSG00000025003, Cyp2c39, cytochrome P450, family 2, subfamily c, polypeptide 39, [RH, Score=268, Expect=3e-83]; ENSMUSG00000060613, Cyp2c70, cytochrome P450, family 2, subfamily c, polypeptide 70, [RH, Score=265, Expect=2e-82]; ENSMUSG00000067229, Cyp2c66, cytochrome P450, family 2, subfamily c, polypeptide 66, [RH, Score=265, Expect=2e-82]} {Dmel: FBgn0036910, Cyp305a1, [RH, Score=211, Expect=1e-61]} {Celegans: WBGene00016860, cyp-33C9, CYtochrome P450 family, [RH, Score=266, Expect=4e-83]} {Smed: dd_Smed_v6_3919_0_2, dd_Smed_v6_3919_0_2, [RH, Score=300, Expect=8e-96]} {RNA1509_13304} {RNA1310_8293.2, RNA1509_13304} {RNA1509_13304, RNA815_6048}
51. MligTC455_43923 1485 30.93 Mlig455_051179

Neo: -

Age: -

Region-enriched R3: 2.085/0.00351

SLC5A9 2.603 0.812 - - 0.953 0.838 - Mlig455_051179 {REF} {Length: 3805} {Pfam: Sodium:solute symporter family [PF00474.19, score=204.7]} {Human: ENSG00000117834, SLC5A9, solute carrier family 5 member 9, [Score=384, Expect=2e-126]; ENSG00000100170, SLC5A1, solute carrier family 5 member 1, [Score=370, Expect=4e-123]} {Mouse: ENSMUSG00000028544, Slc5a9, solute carrier family 5 (sodium/glucose cotransporter), member 9, [Score=392, Expect=1e-129]; ENSMUSG00000011034, Slc5a1, solute carrier family 5 (sodium/glucose cotransporter), member 1, [Score=384, Expect=5e-127]} {Smed: dd_Smed_v6_6663_0_1, dd_Smed_v6_6663_0_1, [Score=478, Expect=1e-163]} {RNA1509_1500, RNA1509_19405} {RNA1310_2456.1, RNA1509_1500, RNA1509_19405} {RNA1509_1500, RNA1509_19405, RNA815_1533}
52. MligTC455_24111 2133 44.44 Mlig455_006522

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.520

Region-enriched R3: 2.075/0.00302

Regeneration-enriched TP: 3.884
Regeneration-enriched R5: 2.767
Regeneration-enriched BL: 2.705

CYP2U1 2.597 0.776 - - 0.869 - 0.952 Mlig455_006522 {REF} {Length: 2950} {Pfam: Cytochrome P450 [PF00067.24, score=343.0]} {Human: ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=264, Expect=2e-81]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [RH, Score=261, Expect=9e-81]; ENSG00000283284, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=260, Expect=2e-80]; ENSG00000275211, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [RH, Score=259, Expect=2e-80]; ENSG00000100197, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=5e-80]; ENSG00000280905, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=7e-80]; ENSG00000272532, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=7e-80]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [RH, Score=258, Expect=2e-79]; ENSG00000272000, AC236040.1, cytochrome P450 family 2 subfamily D member 6 pseudogene, [RH, Score=258, Expect=7e-80]; ENSG00000282966, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=7e-80]} {Mouse: ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [RH, Score=285, Expect=2e-90]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=283, Expect=2e-89]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=276, Expect=1e-86]} {Dmel: FBgn0001992, Cyp303a1, [RH, Score=204, Expect=2e-59]} {Celegans: WBGene00016860, cyp-33C9, CYtochrome P450 family, [RH, Score=247, Expect=7e-76]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [RH, Score=290, Expect=4e-92]} {RNA1509_15086, RNA1509_20987, RNA1509_30191, RNA1509_36041, RNA1509_38086, RNA1509_42174, RNA1509_42907, RNA1509_54185} {RNA1310_10025, RNA1509_15086, RNA1509_20987, RNA1509_30191, RNA1509_36041, RNA1509_38086, RNA1509_42174, RNA1509_42907, RNA1509_54185} {RNA1509_15086, RNA1509_20987, RNA1509_30191, RNA1509_36041, RNA1509_38086, RNA1509_42174, RNA1509_42907, RNA1509_54185, RNA815_4606.1}
53. MligTC455_14929 91 1.89 Mlig455_057903

Neo: -

Age: Up-Down-Up

Region-enriched R4: 3.368/0.00382
Region-enriched R5: 2.291/0.02790

MYRF 2.57 - - - 0.785 0.829 0.956 Mlig455_057903 {REF} {Length: 5413} {Pfam: NDT80 / PhoG like DNA-binding family [PF05224.14, score=71.1]; Myelin regulatory factor ICA domain [PF13887.8, score=54.1]; Chaperone of endosialidase [PF13884.8, score=29.0]} {Human: ENSG00000124920, MYRF, myelin regulatory factor, [RH, Score=263, Expect=4e-72]} {Mouse: ENSMUSG00000036098, Myrf, myelin regulatory factor, [RH, Score=264, Expect=2e-72]} {Dmel: FBgn0034985, CG3328, [RH, Score=258, Expect=3e-70]} {Celegans: WBGene00004134, myrf-1, Myelin regulatory factor related, [RH, Score=161, Expect=4e-40]} {RNA1509_22033, RNA1509_38808} {RNA1310_10550.1, RNA1509_22033, RNA1509_38808} {RNA1509_22033, RNA1509_38808, RNA815_10911}
54. MligTC455_45265 2220 46.25 Mlig455_002161, Mlig455_002262, Mlig455_002307

Neo: -

Age: -

Region-enriched R4: 2.277/0.00075
Region-enriched R3: 1.605/0.01626
Region-enriched R5: 1.543/0.00597

CAPSL 2.552 - - - 0.833 0.761 0.958

Mlig455_002161 {REF} {Length: 1013} {Pfam: EF-hand domain pair [PF13499.8, score=74.8]; EF-hand domain [PF13405.8, score=64.7]; EF hand [PF00036.34, score=64.1]; EF-hand domain pair [PF13833.8, score=46.6]; EF hand [PF13202.8, score=41.9]; p25-alpha [PF05517.14, score=25.0]} {Human: ENSG00000152611, CAPSL, calcyphosine like, [Score=256, Expect=8e-87]} {Mouse: ENSMUSG00000039676, Capsl, calcyphosine-like, [Score=259, Expect=3e-88]} {Dmel: FBgn0051345, CG31345, [Score=238, Expect=7e-80]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=52.4, Expect=1e-08]} {Smed: dd_Smed_v6_7209_0_1, dd_Smed_v6_7209_0_1, [RH, Score=291, Expect=4e-101]} {RNA1509_35855} {RNA1310_1867.1} {RNA815_8990}

Mlig455_002262 {REF} {Length: 1131} {Pfam: EF-hand domain pair [PF13499.8, score=74.7]; EF-hand domain [PF13405.8, score=64.7]; EF hand [PF00036.34, score=64.1]; EF-hand domain pair [PF13833.8, score=46.6]; EF hand [PF13202.8, score=41.9]; p25-alpha [PF05517.14, score=25.0]} {Human: ENSG00000152611, CAPSL, calcyphosine like, [Score=254, Expect=2e-86]} {Mouse: ENSMUSG00000039676, Capsl, calcyphosine-like, [Score=260, Expect=1e-88]} {Dmel: FBgn0051345, CG31345, [Score=238, Expect=7e-80]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=52.4, Expect=1e-08]} {Smed: dd_Smed_v6_7209_0_1, dd_Smed_v6_7209_0_1, [RH, Score=291, Expect=2e-101]} {RNA1509_35855, RNA1509_47023} {RNA1310_1867.1, RNA1509_35855, RNA1509_47023} {RNA1509_35855, RNA1509_47023, RNA815_8990}

Mlig455_002307 {REF} {Length: 1149} {Pfam: EF-hand domain pair [PF13499.8, score=74.9]; EF-hand domain [PF13405.8, score=64.7]; EF hand [PF00036.34, score=64.1]; EF-hand domain pair [PF13833.8, score=46.6]; EF hand [PF13202.8, score=42.0]; p25-alpha [PF05517.14, score=25.0]} {Human: ENSG00000152611, CAPSL, calcyphosine like, [Score=255, Expect=1e-86]} {Mouse: ENSMUSG00000039676, Capsl, calcyphosine-like, [Score=258, Expect=4e-88]} {Dmel: FBgn0051345, CG31345, [Score=238, Expect=7e-80]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=52.4, Expect=1e-08]} {Smed: dd_Smed_v6_7209_0_1, dd_Smed_v6_7209_0_1, [RH, Score=291, Expect=3e-101]} {RNA1509_47023} {RNA1310_29487} {RNA815_8990}
55. MligTC455_46189 3465 72.19 Mlig455_064483

Neo: -

Age: -

Region-enriched R3: 2.108/0.00000
Region-enriched R4: 1.352/0.02878
Region-enriched R5: 1.186/0.01606

ENPEP 2.549 0.848 - - 0.733 - 0.968 Mlig455_064483 {REF} {Length: 3574} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=253.3]; Peptidase family M1 domain [PF01433.22, score=243.6]; Peptidase M1 N-terminal domain [PF17900.3, score=149.2]} {Human: ENSG00000138792, ENPEP, glutamyl aminopeptidase, [RH, Score=590, Expect=0.0]} {Mouse: ENSMUSG00000028024, Enpep, glutamyl aminopeptidase, [RH, Score=590, Expect=0.0]} {Dmel: FBgn0038135, CG8773, [RH, Score=610, Expect=0.0]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=369, Expect=3e-112]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=479, Expect=2e-153]} {RNA1509_40879, RNA1509_41090, RNA1509_50042, RNA1509_56083, RNA1509_690, RNA1509_9985} {RNA1310_3977.1, RNA1509_40879, RNA1509_41090, RNA1509_50042, RNA1509_56083, RNA1509_690, RNA1509_9985} {RNA1509_40879, RNA1509_41090, RNA1509_50042, RNA1509_56083, RNA1509_690, RNA1509_9985, RNA815_1584}
56. MligTC455_42353 5099 106.23 Mlig455_014274, Mlig455_014309, Mlig455_018673

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.786

Region-enriched R3: 2.226/0.00003

AC113554.1, ACE 2.548 0.874 - - 0.711 - 0.963

Mlig455_014274 {REF} {Length: 2949} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=705.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0016122, Acer, Angiotensin-converting enzyme-related, [RH, Score=426, Expect=4e-141]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=191, Expect=3e-51]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=411, Expect=1e-135]} {RNA1509_37062, RNA1509_441} {RNA1310_8949, RNA1509_37062} {RNA1509_37062, RNA815_4061}

Mlig455_014309 {REF} {Length: 2926} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=705.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0016122, Acer, Angiotensin-converting enzyme-related, [RH, Score=426, Expect=4e-141]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=191, Expect=3e-51]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=411, Expect=1e-135]} {RNA1509_441} {RNA1310_8949} {RNA815_4061}

Mlig455_018673 {REF} {Length: 833} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=122.4]} {Human: ENSG00000264813, AC113554.1, novel transcript, [Score=103, Expect=3e-24]; ENSG00000159640, ACE, angiotensin I converting enzyme, [Score=103, Expect=2e-24]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [Score=97.8, Expect=2e-22]; ENSMUSG00000101605, Ace3, angiotensin I converting enzyme (peptidyl-dipeptidase A) 3, [Score=93.2, Expect=6e-21]} {Dmel: FBgn0012037, Ance, Angiotensin converting enzyme, [Score=74.7, Expect=7e-15]} {Smed: dd_Smed_v6_13804_0_1, dd_Smed_v6_13804_0_1, [Score=51.2, Expect=2e-07]} {RNA1509_16360} {RNA1310_8949} {RNA815_4061}
57. MligTC455_33577 18072 376.49 Mlig455_043957, Mlig455_043969, Mlig455_044039

Neo: -

Age: logFC(26M/2M)=0.423

Region-enriched R5: 1.425/0.00134
Region-enriched R4: 1.282/0.02044

IDH1 2.544 0.727 - - 0.964 - 0.853

Mlig455_043957 {REF} {Length: 2414} {Pfam: Isocitrate/isopropylmalate dehydrogenase [PF00180.22, score=266.7]} {Human: ENSG00000138413, IDH1, isocitrate dehydrogenase (NADP(+)) 1, cytosolic, [RH, Score=664, Expect=0.0]} {Mouse: ENSMUSG00000025950, Idh1, isocitrate dehydrogenase 1 (NADP+), soluble, [RH, Score=660, Expect=0.0]} {Dmel: FBgn0001248, Idh, Isocitrate dehydrogenase, [RH, Score=636, Expect=0.0]} {Celegans: WBGene00010317, idh-1, Isocitrate dehydrogenase [NADP], [RH, Score=651, Expect=0.0]} {Smed: dd_Smed_v6_3770_0_1, dd_Smed_v6_3770_0_1, [RH, Score=652, Expect=0.0]} {RNA1509_16912} {RNA1310_10691.1, RNA1509_16912} {RNA1509_16912, RNA815_3934}

Mlig455_043969 {REF} {Length: 2413} {Pfam: Isocitrate/isopropylmalate dehydrogenase [PF00180.22, score=267.0]} {Human: ENSG00000138413, IDH1, isocitrate dehydrogenase (NADP(+)) 1, cytosolic, [RH, Score=667, Expect=0.0]} {Mouse: ENSMUSG00000025950, Idh1, isocitrate dehydrogenase 1 (NADP+), soluble, [RH, Score=664, Expect=0.0]} {Dmel: FBgn0001248, Idh, Isocitrate dehydrogenase, [RH, Score=639, Expect=0.0]} {Celegans: WBGene00010317, idh-1, Isocitrate dehydrogenase [NADP], [RH, Score=654, Expect=0.0]} {Smed: dd_Smed_v6_3770_0_1, dd_Smed_v6_3770_0_1, [RH, Score=655, Expect=0.0]} {RNA1509_16912, RNA1509_26642, RNA1509_847} {RNA1310_10691.1, RNA1509_26642, RNA1509_847} {RNA1509_26642, RNA1509_847, RNA815_3934}

Mlig455_044039 {REF} {Length: 2905} {Pfam: Isocitrate/isopropylmalate dehydrogenase [PF00180.22, score=267.0]} {Human: ENSG00000138413, IDH1, isocitrate dehydrogenase (NADP(+)) 1, cytosolic, [RH, Score=667, Expect=0.0]} {Mouse: ENSMUSG00000025950, Idh1, isocitrate dehydrogenase 1 (NADP+), soluble, [RH, Score=664, Expect=0.0]} {Dmel: FBgn0001248, Idh, Isocitrate dehydrogenase, [RH, Score=639, Expect=0.0]} {Celegans: WBGene00010317, idh-1, Isocitrate dehydrogenase [NADP], [RH, Score=654, Expect=0.0]} {Smed: dd_Smed_v6_3770_0_1, dd_Smed_v6_3770_0_1, [RH, Score=655, Expect=0.0]} {RNA1509_16912, RNA1509_38467} {RNA1310_10691.1, RNA1509_38467} {RNA1509_38467, RNA815_3934}
58. MligTC455_33006 2208 45.99 Mlig455_063158

Neo: -

Age: Down-Up-Up

Region-enriched R4: 2.219/0.00001
Region-enriched R3: 1.514/0.00240

2.542 - 0.712 - - 0.958 0.872 Mlig455_063158 {REF} {Length: 2059} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=27.0]} {RNA1509_4524} {RNA1310_31808} {RNA815_13487}
59. MligTC455_11353 696 14.51 Mlig455_004383, Mlig455_037197

Neo: Germline

Age: Up-Down-Down

Region-specific R4: 4.069

2.529 - - - 0.723 0.959 0.847

Mlig455_004383 {REF} {Length: 3587} {RNA1509_23567} {RNA1310_21215} {RNA815_19894}

Mlig455_037197 {REF} {Length: 4232} {RNA1509_23567} {RNA1310_21215, RNA1509_23567} {RNA1509_23567, RNA815_19894}
60. MligTC455_14995 586 12.21 Mlig455_059220

Neo: -

Age: logFC(26M/2M)=0.367

Region-enriched R3: 2.356/0.00181
Region-enriched R4: 2.017/0.02020

ENOSF1 2.528 - - - 0.751 0.792 0.985 Mlig455_059220 {REF} {Length: 1808} {Pfam: Enolase C-terminal domain-like [PF13378.8, score=157.1]; Mandelate racemase / muconate lactonizing enzyme, N-terminal domain [PF02746.18, score=56.9]} {Human: ENSG00000132199, ENOSF1, enolase superfamily member 1, [Score=82.8, Expect=1e-16]} {Smed: dd_Smed_v6_2923_0_1, dd_Smed_v6_2923_0_1, [Score=69.7, Expect=8e-13]} {RNA1509_8789} {RNA1310_17249.1, RNA1509_8789} {RNA1509_8789, RNA815_6768.1}
61. MligTC455_44645 563 11.72 Mlig455_070220

Neo: -

Age: -

SLC28A1 2.523 0.727 - - 0.950 - 0.846 Mlig455_070220 {REF} {Length: 2524} {Pfam: Na+ dependent nucleoside transporter C-terminus [PF07662.15, score=236.4]; Na+ dependent nucleoside transporter N-terminus [PF01773.22, score=73.8]; Nucleoside recognition [PF07670.16, score=23.7]} {Human: ENSG00000156222, SLC28A1, solute carrier family 28 member 1, [RH, Score=377, Expect=7e-123]; ENSG00000137860, SLC28A2, solute carrier family 28 member 2, [RH, Score=369, Expect=3e-119]} {Mouse: ENSMUSG00000027219, Slc28a2, solute carrier family 28 (sodium-coupled nucleoside transporter), member 2, [RH, Score=385, Expect=6e-126]; ENSMUSG00000025726, Slc28a1, solute carrier family 28 (sodium-coupled nucleoside transporter), member 1, [RH, Score=377, Expect=1e-122]} {Dmel: FBgn0025709, CNT2, Concentrative nucleoside transporter 2, [Score=300, Expect=5e-94]} {Celegans: WBGene00017868, slc-28.2, Sodium/nucleoside cotransporter, [RH, Score=240, Expect=2e-71]} {Smed: dd_Smed_v6_3508_0_1, dd_Smed_v6_3508_0_1, [Score=456, Expect=3e-154]} {RNA1509_20711, RNA1509_21619, RNA1509_48971} {RNA1310_7732, RNA1509_20711, RNA1509_21619, RNA1509_48971} {RNA1509_20711, RNA1509_21619, RNA1509_48971, RNA815_2578}
62. MligTC455_15783 5345 111.36 Mlig455_025807, Mlig455_025814

Neo: -

Age: -

Region-enriched R4: 1.633/0.00032
Region-enriched R5: 1.583/0.00001
Region-enriched R6: 1.083/0.03690

GULP1 2.505 0.739 - - 0.952 - 0.814

Mlig455_025807 {REF} {Length: 1817} {TRANSSPLICED} {Pfam: Phosphotyrosine interaction domain (PTB/PID) [PF00640.25, score=36.5]} {Human: ENSG00000144366, GULP1, GULP, engulfment adaptor PTB domain containing 1, [Score=59.3, Expect=2e-09]} {Mouse: ENSMUSG00000056870, Gulp1, GULP, engulfment adaptor PTB domain containing 1, [Score=56.6, Expect=1e-08]; ENSMUSG00000024219, Anks1, ankyrin repeat and SAM domain containing 1, [Score=53.9, Expect=2e-07]} {Dmel: FBgn0029092, ced-6, [RH, Score=69.7, Expect=1e-12]} {Celegans: WBGene00000420, ced-6, Cell death protein 6, [Score=49.3, Expect=3e-06]} {RNA1509_14211, RNA1509_2504} {RNA1310_16087, RNA1509_14211, RNA1509_2504} {RNA1509_14211, RNA1509_2504, RNA815_6763}

Mlig455_025814 {REF} {Length: 1818} {TRANSSPLICED} {Pfam: Phosphotyrosine interaction domain (PTB/PID) [PF00640.25, score=36.5]} {Human: ENSG00000144366, GULP1, GULP, engulfment adaptor PTB domain containing 1, [Score=59.7, Expect=2e-09]} {Mouse: ENSMUSG00000056870, Gulp1, GULP, engulfment adaptor PTB domain containing 1, [Score=56.6, Expect=1e-08]} {Dmel: FBgn0029092, ced-6, [RH, Score=68.2, Expect=3e-12]} {Celegans: WBGene00000420, ced-6, Cell death protein 6, [Score=47.8, Expect=8e-06]} {RNA1509_2504, RNA1509_44856, RNA1509_48464, RNA1509_9772} {RNA1310_16087, RNA1509_44856, RNA1509_48464, RNA1509_9772} {RNA1509_44856, RNA1509_48464, RNA1509_9772, RNA815_6763}
63. MligTC455_34797 883 18.39 Mlig455_033462

Neo: -

Age: Up-Down-Up

Region-enriched R4: 1.410/0.04497

PZP 2.476 0.779 - - 0.962 - 0.735 Mlig455_033462 {REF} {Length: 6119} {TRANSSPLICED} {Pfam: A-macroglobulin TED domain [PF07678.16, score=112.0]; A-macroglobulin receptor binding domain [PF07677.16, score=62.2]; Alpha-2-macroglobulin bait region domain [PF07703.16, score=55.9]; Alpha-2-macroglobulin family [PF00207.24, score=45.8]; MG2 domain [PF01835.21, score=35.2]; Macroglobulin domain MG3 [PF17791.3, score=21.3]} {Human: ENSG00000126838, PZP, PZP, alpha-2-macroglobulin like, [Score=179, Expect=2e-44]} {Mouse: ENSMUSG00000030111, A2m, alpha-2-macroglobulin, [Score=174, Expect=3e-43]; ENSMUSG00000030359, Pzp, PZP, alpha-2-macroglobulin like, [Score=171, Expect=3e-42]} {Dmel: FBgn0267488, Mcr, Macroglobulin complement-related, [RH, Score=531, Expect=1e-159]} {Celegans: WBGene00013969, tep-1, TEP (ThiolEster containing Protein), [Score=233, Expect=1e-61]} {Smed: dd_Smed_v6_3070_0_1, dd_Smed_v6_3070_0_1, [RH, Score=1325, Expect=0.0]} {RNA1509_8466} {RNA1310_642.1} {RNA815_286.1}
64. MligTC455_39261 2000 41.67 Mlig455_036509, Mlig455_069140

Neo: -

Age: logFC(26M/2M)=-0.812

2.475 0.725 - - 0.787 - 0.963

Mlig455_036509 {REF} {Length: 2142} {RNA1509_28747} {RNA1310_48185.2} {RNA815_28254}

Mlig455_069140 {REF} {Length: 3743} {RNA1509_28747, RNA1509_33325, RNA1509_34343} {RNA1310_46864, RNA1509_28747, RNA1509_33325, RNA1509_34343} {RNA1509_28747, RNA1509_33325, RNA1509_34343, RNA815_28254}
65. MligTC455_44838 1113 23.18 Mlig455_035218, Mlig455_035266

Neo: -

Age: -

MAN2B1 2.458 0.709 0.786 - - - 0.963

Mlig455_035218 {REF} {Length: 3151} {Pfam: Glycosyl hydrolases family 38 N-terminal domain [PF01074.24, score=269.2]; Alpha mannosidase middle domain [PF09261.13, score=64.9]; Glycosyl hydrolases family 38 C-terminal domain [PF07748.15, score=44.0]; Glycosyl hydrolases family 38 C-terminal beta sandwich domain [PF17677.3, score=32.3]} {Human: ENSG00000104774, MAN2B1, mannosidase alpha class 2B member 1, [Score=630, Expect=0.0]} {Mouse: ENSMUSG00000005142, Man2b1, mannosidase 2, alpha B1, [Score=607, Expect=0.0]} {Dmel: FBgn0027611, LManII, Lysosomal alpha-mannosidase II, [Score=636, Expect=0.0]} {Celegans: WBGene00018877, aman-1, Alpha-mannosidase, [RH, Score=502, Expect=9e-163]} {Smed: dd_Smed_v6_1942_0_1, dd_Smed_v6_1942_0_1, [Score=674, Expect=0.0]} {RNA1509_7785} {RNA1310_4896.1, RNA1509_7785} {RNA1509_7785, RNA815_7617}

Mlig455_035266 {REF} {Length: 2979} {Pfam: Glycosyl hydrolases family 38 N-terminal domain [PF01074.24, score=189.2]; Alpha mannosidase middle domain [PF09261.13, score=64.8]; Glycosyl hydrolases family 38 C-terminal domain [PF07748.15, score=45.6]; Glycosyl hydrolases family 38 C-terminal beta sandwich domain [PF17677.3, score=32.4]} {Human: ENSG00000104774, MAN2B1, mannosidase alpha class 2B member 1, [Score=531, Expect=1e-173]} {Mouse: ENSMUSG00000005142, Man2b1, mannosidase 2, alpha B1, [Score=501, Expect=6e-162]} {Dmel: FBgn0027611, LManII, Lysosomal alpha-mannosidase II, [Score=538, Expect=2e-175]} {Celegans: WBGene00018877, aman-1, Alpha-mannosidase, [Score=428, Expect=4e-135]} {Smed: dd_Smed_v6_1942_0_1, dd_Smed_v6_1942_0_1, [Score=566, Expect=0.0]} {RNA1509_7785} {RNA1310_4896.1} {RNA815_7617}
66. MligTC455_41521 1793 37.36 Mlig455_057588

Neo: -

Age: -

Region-enriched R5: 1.375/0.00000
Region-enriched R3: 1.257/0.00033
Region-enriched R4: 1.049/0.01657

2.404 - 0.711 - 0.962 - 0.731 Mlig455_057588 {REF} {Length: 2069} {TRANSSPLICED} {RNA1509_22303, RNA1509_3842, RNA1509_41783, RNA1509_9152} {RNA1310_16812.1, RNA1509_22303, RNA1509_3842, RNA1509_41783, RNA1509_9152} {RNA1509_22303, RNA1509_3842, RNA1509_41783, RNA1509_9152, RNA815_17534}
67. MligTC455_50448 759 15.81 Mlig455_064452

Neo: -

Age: logFC(26M/2M)=-0.850

KREMEN1 1.877 - - - 0.907 - 0.970 Mlig455_064452 {REF} {Length: 819} {Pfam: WSC domain [PF01822.21, score=61.7]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=52.4, Expect=9e-08]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=50.8, Expect=3e-08]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=53.9, Expect=1e-08]} {RNA1509_12393} {RNA1310_56240.1} {RNA815_26405}
68. MligTC455_25204 538 11.21 Mlig455_069579

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.471

Region-enriched R3: 3.220/0.00014
Region-enriched R5: 1.890/0.03760

1.865 0.910 - - - - 0.955 Mlig455_069579 {REF} {Length: 3907} {RNA1509_37038} {RNA1310_15345} {RNA815_1099}
69. MligTC455_17727 4189 87.27 Mlig455_057688, Mlig455_059984

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.941

Region-enriched R6: 2.088/0.01181
Region-enriched R5: 1.460/0.04298

1.863 - - - 0.912 - 0.951

Mlig455_057688 {REF} {Length: 980} {RNA1509_889} {RNA1310_48596} {RNA815_26649}

Mlig455_059984 {REF} {Length: 988} {RNA1509_14511, RNA1509_20501, RNA1509_889} {RNA1310_48596, RNA1509_14511, RNA1509_20501, RNA1509_889} {RNA1509_14511, RNA1509_20501, RNA1509_889, RNA815_26649}
70. MligTC455_17728 1061 22.09 Mlig455_057691

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-4.029

Region-enriched R6: 1.981/0.02890

1.856 - - - 0.966 - 0.890 Mlig455_057691 {REF} {Length: 717} {RNA1509_20501} {RNA1310_48596} {RNA815_26649}
71. MligTC455_44644 368 7.66 Mlig455_012549

Neo: -

Age: -

1.856 - - - 0.965 - 0.891 Mlig455_012549 {REF} {Length: 1215} {NoTransDecoderORF} {RNA1509_48971} {RNA1310_7732} {RNA815_2578}
72. MligTC455_48966 1196 24.92 Mlig455_011970

Neo: -

Age: logFC(26M/2M)=0.730

Region-enriched R4: 2.185/0.00002
Region-enriched R5: 1.169/0.00499

1.856 - - - 0.962 - 0.894 Mlig455_011970 {REF} {Length: 667} {TRANSSPLICED} {Pfam: Type III secretion system lipoprotein chaperone (YscW) [PF09619.12, score=24.6]} {RNA1509_11772} {RNA1310_19739.1} {RNA815_20380}
73. MligTC455_23221 236 4.91 Mlig455_003590, Mlig455_015401

Neo: -

Age: -

1.851 - - - 0.888 - 0.963

Mlig455_003590 {REF} {Length: 1425} {Pfam: Siphovirus Gp157 [PF05565.13, score=18.7]} {RNA1509_49661, RNA1509_56563} {RNA1310_25909, RNA1509_49661, RNA1509_56563} {RNA1509_49661, RNA1509_56563, RNA815_10495.2}

Mlig455_015401 {REF} {Length: 2622} {Pfam: Siphovirus Gp157 [PF05565.13, score=18.7]} {RNA1509_49661} {RNA1310_25909} {RNA815_10495.2}
74. MligTC455_53355 1190 24.78 Mlig455_033338, Mlig455_033357

Neo: -

Age: -

Region-enriched R4: 1.851/0.00149

1.85 - - - 0.973 - 0.877

Mlig455_033338 {REF} {Length: 1291} {RNA1509_14712, RNA1509_46611} {RNA1310_36401.2, RNA1509_46611} {RNA1509_46611, RNA815_17710}

Mlig455_033357 {REF} {Length: 973} {TRANSSPLICED} {RNA1509_14712} {RNA1310_36401.2} {RNA815_17710}
75. MligTC455_53356 1170 24.37 Mlig455_033344, Mlig455_033363

Neo: -

Age: -

Region-enriched R4: 2.114/0.00122
Region-enriched R5: 1.062/0.04423

TMED7 1.837 - - - 0.959 - 0.878

Mlig455_033344 {REF} {Length: 1935} {Pfam: emp24/gp25L/p24 family/GOLD [PF01105.26, score=115.7]} {Human: ENSG00000134970, TMED7, transmembrane p24 trafficking protein 7, [Score=110, Expect=2e-29]} {Mouse: ENSMUSG00000033184, Tmed7, transmembrane p24 trafficking protein 7, [Score=110, Expect=3e-29]} {Dmel: FBgn0030341, p24-1, p24-related-1, [Score=116, Expect=6e-32]} {Celegans: WBGene00019003, F57B10.5, [Score=97.8, Expect=5e-25]} {Smed: dd_Smed_v6_2557_0_1, dd_Smed_v6_2557_0_1, [Score=98.2, Expect=4e-25]} {RNA1509_14712} {RNA1310_32912, RNA1509_14712} {RNA1509_14712, RNA815_16911}

Mlig455_033363 {REF} {Length: 1946} {Pfam: emp24/gp25L/p24 family/GOLD [PF01105.26, score=115.8]} {Human: ENSG00000134970, TMED7, transmembrane p24 trafficking protein 7, [Score=110, Expect=2e-29]} {Mouse: ENSMUSG00000033184, Tmed7, transmembrane p24 trafficking protein 7, [Score=110, Expect=2e-29]} {Dmel: FBgn0030341, p24-1, p24-related-1, [Score=114, Expect=2e-31]} {Celegans: WBGene00019003, F57B10.5, [Score=97.4, Expect=8e-25]} {Smed: dd_Smed_v6_2557_0_1, dd_Smed_v6_2557_0_1, [Score=98.6, Expect=3e-25]} {RNA1509_14712} {RNA1310_32912} {RNA815_16911}
76. MligTC455_51192 305 6.35 Mlig455_065957

Neo: -

Age: Up-Down-Up

Region-enriched R3: 2.100/0.00201

1.831 0.868 - - - - 0.963 Mlig455_065957 {REF} {Length: 2609} {Pfam: Innexin [PF00876.20, score=323.9]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=88.6, Expect=5e-19]} {Celegans: WBGene00002123, inx-1, Innexin, [Score=261, Expect=5e-84]} {Smed: dd_Smed_v6_734_0_1, dd_Smed_v6_734_0_1, [Score=273, Expect=3e-88]} {RNA1509_22191, RNA1509_47818} {RNA1310_9582, RNA1509_47818} {RNA1509_47818, RNA815_10664}
77. MligTC455_34415 257 5.35 Mlig455_004409

Neo: -

Age: -

1.828 - - - - 0.863 0.965 Mlig455_004409 {REF} {Length: 2248} {RNA1509_21160} {RNA1310_6052} {RNA815_47286}
78. MligTC455_48498 1066 22.21 Mlig455_007871

Neo: -

Age: logFC(26M/2M)=0.286

Region-enriched R3: 1.717/0.03337

MICU3 1.819 - - - - 0.834 0.985 Mlig455_007871 {REF} {Length: 2576} {Pfam: EF-hand domain pair [PF13499.8, score=34.5]; EF-hand domain [PF13405.8, score=34.4]; EF-hand domain pair [PF13833.8, score=32.0]; EF hand [PF00036.34, score=30.6]; EF hand [PF13202.8, score=22.8]} {Human: ENSG00000155970, MICU3, mitochondrial calcium uptake family member 3, [Score=260, Expect=1e-82]} {Mouse: ENSMUSG00000021973, Micu2, mitochondrial calcium uptake 2, [Score=216, Expect=3e-65]; ENSMUSG00000039478, Micu3, mitochondrial calcium uptake family, member 3, [Score=214, Expect=2e-63]} {Dmel: FBgn0038735, CG4662, [Score=282, Expect=3e-90]} {Celegans: WBGene00008345, C56A3.6, [RH, Score=239, Expect=1e-74]} {Smed: dd_Smed_v6_5430_0_1, dd_Smed_v6_5430_0_1, [Score=204, Expect=9e-61]} {RNA1509_14710, RNA1509_26156} {RNA1310_3702, RNA1509_14710, RNA1509_26156} {RNA1509_14710, RNA1509_26156, RNA815_171.2}
79. MligTC455_54233 326 6.8 Mlig455_024221

Neo: -

Age: -

LRRC74A 1.81 - - - - 0.857 0.953 Mlig455_024221 {REF} {Length: 2065} {Pfam: Leucine Rich repeat [PF13516.8, score=46.3]; EF-hand domain [PF13405.8, score=28.6]; EF-hand domain pair [PF13499.8, score=23.6]; EF hand [PF00036.34, score=20.2]} {Human: ENSG00000100565, LRRC74A, leucine rich repeat containing 74A, [Score=138, Expect=3e-35]} {Mouse: ENSMUSG00000059114, Lrrc74a, leucine rich repeat containing 74A, [Score=134, Expect=4e-34]} {Smed: dd_Smed_v6_14506_0_1, dd_Smed_v6_14506_0_1, [Score=166, Expect=2e-45]} {RNA1509_42121} {RNA1310_35739} {RNA815_18880}
80. MligTC455_36347 2542 52.97 Mlig455_027675

Neo: -

Age: -

ACP7 1.806 - - - - 0.844 0.962 Mlig455_027675 {REF} {Length: 2194} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=89.6]; Iron/zinc purple acid phosphatase-like protein C [PF14008.8, score=79.5]; Purple acid Phosphatase, N-terminal domain [PF16656.7, score=75.2]; PhoD-like phosphatase [PF09423.12, score=19.2]} {Human: ENSG00000183760, ACP7, acid phosphatase 7, tartrate resistant (putative), [RH, Score=431, Expect=2e-148]} {Mouse: ENSMUSG00000037469, Acp7, acid phosphatase 7, tartrate resistant, [RH, Score=448, Expect=1e-154]} {Dmel: FBgn0030245, CG1637, [RH, Score=434, Expect=9e-150]} {Celegans: WBGene00219316, F21A3.11, Purple acid phosphatase, [RH, Score=406, Expect=2e-138]} {Smed: dd_Smed_v6_1053_0_1, dd_Smed_v6_1053_0_1, [RH, Score=537, Expect=0.0]} {RNA1509_2158} {RNA1310_12511.1, RNA1509_2158} {RNA1509_2158, RNA815_6230.1}
81. MligTC455_32901 454 9.47 Mlig455_067826

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.415

Region-enriched R3: 2.470/0.00379

CA7 1.794 - - - - 0.814 0.980 Mlig455_067826 {REF} {Length: 1496} {Pfam: Eukaryotic-type carbonic anhydrase [PF00194.23, score=243.6]} {Human: ENSG00000168748, CA7, carbonic anhydrase 7, [RH, Score=207, Expect=8e-66]; ENSG00000133742, CA1, carbonic anhydrase 1, [RH, Score=197, Expect=1e-61]} {Mouse: ENSMUSG00000027562, Car2, carbonic anhydrase 2, [RH, Score=204, Expect=1e-64]} {Dmel: FBgn0027844, CAH1, Carbonic anhydrase 1, [Score=192, Expect=2e-60]} {Celegans: WBGene00000281, cah-3, Putative carbonic anhydrase 3, [RH, Score=137, Expect=2e-39]} {Smed: dd_Smed_v6_5784_0_1, dd_Smed_v6_5784_0_1, [Score=187, Expect=4e-58]} {RNA1509_23444, RNA1509_34487} {RNA1310_23047.1, RNA1509_23444, RNA1509_34487} {RNA1509_23444, RNA1509_34487, RNA815_11571.2}
82. MligTC455_35665 550 11.46 Mlig455_000411

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.492

AC099489.1 1.777 - - - - 0.819 0.958 Mlig455_000411 {REF} {Length: 12958} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=89.4]; Domain of unknown function (DUF1943) [PF09172.13, score=66.3]; von Willebrand factor type D domain [PF00094.27, score=25.5]} {Human: ENSG00000188897, AC099489.1, vitellogenin, [Score=122, Expect=1e-26]} {Dmel: FBgn0032136, Apoltp, Apolipoprotein lipid transfer particle, [Score=74.3, Expect=3e-12]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=93.6, Expect=3e-18]} {RNA1509_862} {RNA1310_65.2} {RNA815_55}
83. MligTC455_45315 4773 99.43 Mlig455_037736

Neo: -

Age: -

1.773 - - - - 0.793 0.980 Mlig455_037736 {REF} {Length: 2269} {RNA1509_18494, RNA1509_5801} {RNA1310_12524.1, RNA1509_5801} {RNA1509_5801, RNA815_3944.1}
84. MligTC455_40402 1554 32.37 Mlig455_000952

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.970

Region-enriched R3: 1.461/0.00007

1.762 - - - - 0.807 0.955 Mlig455_000952 {REF} {Length: 1951} {TRANSSPLICED} {Pfam: Tetraspanin family [PF00335.22, score=79.6]} {Dmel: FBgn0036769, Tsp74F, Tetraspanin 74F, [Score=52.0, Expect=2e-07]} {Smed: dd_Smed_v6_3175_0_1, dd_Smed_v6_3175_0_1, [Score=97.8, Expect=1e-23]} {RNA1509_15457, RNA1509_28774, RNA1509_4864} {RNA1310_21230.1, RNA1509_15457, RNA1509_28774, RNA1509_4864} {RNA1509_15457, RNA1509_28774, RNA1509_4864, RNA815_10297}
85. MligTC455_18866 706 14.71 Mlig455_027285

Neo: -

Age: Down-Up-Down

1.744 - - - - 0.784 0.960 Mlig455_027285 {REF} {Length: 736} {RNA1509_12836} {RNA1310_17576.2} {RNA815_6182.1}
86. MligTC455_13714 219 4.55 Mlig455_039476

Neo: -

Age: -

Region-enriched R4: 5.355/0.00070
Region-enriched R5: 3.269/0.00973

1.742 - - - 0.964 - 0.778 Mlig455_039476 {REF} {Length: 684} {NoTransDecoderORF} {RNA1509_296, RNA1509_36260, RNA1509_3658} {RNA1310_1675.1, RNA1509_296, RNA1509_3658} {RNA1509_296, RNA1509_3658, RNA815_2514.1}
87. MligTC455_50036 1353 28.19 Mlig455_063714

Neo: -

Age: logFC(26M/2M)=-0.294

Region-enriched R4: 1.826/0.00071
Region-enriched R3: 1.745/0.00078
Region-enriched R5: 1.202/0.01353

SPHK1 1.72 - - - 0.760 - 0.960 Mlig455_063714 {REF} {Length: 3647} {TRANSSPLICED} {Pfam: Diacylglycerol kinase catalytic domain [PF00781.26, score=81.8]} {Human: ENSG00000176170, SPHK1, sphingosine kinase 1, [Score=152, Expect=4e-43]} {Mouse: ENSMUSG00000061878, Sphk1, sphingosine kinase 1, [RH, Score=150, Expect=5e-44]; ENSMUSG00000057342, Sphk2, sphingosine kinase 2, [RH, Score=145, Expect=2e-39]} {Dmel: FBgn0030300, Sk1, Sphingosine kinase 1, [RH, Score=145, Expect=1e-39]} {Celegans: WBGene00007918, sphk-1, Sphingosine kinase 1, [Score=120, Expect=2e-31]} {Smed: dd_Smed_v6_5736_0_1, dd_Smed_v6_5736_0_1, [Score=127, Expect=3e-34]} {RNA1509_19326} {RNA1310_4471} {RNA815_1161}
88. MligTC455_45337 3435 71.56 Mlig455_022362

Neo: -

Age: logFC(26M/2M)=-0.291

TXNRD1 1.712 - - - 0.951 - 0.761 Mlig455_022362 {REF} {Length: 2783} {TRANSSPLICED} {Pfam: Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=203.8]; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [PF02852.24, score=78.9]; Glutaredoxin [PF00462.26, score=69.1]; Pyridine nucleotide-disulphide oxidoreductase [PF00070.29, score=64.8]; Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=44.5]; Alanine dehydrogenase/PNT, C-terminal domain [PF01262.23, score=26.5]; FAD binding domain [PF00890.26, score=26.4]; Glucose inhibited division protein A [PF01134.24, score=20.9]; FAD dependent oxidoreductase [PF12831.9, score=20.8]; Thi4 family [PF01946.19, score=19.8]} {Human: ENSG00000198431, TXNRD1, thioredoxin reductase 1, [RH, Score=577, Expect=0.0]; ENSG00000197763, TXNRD3, thioredoxin reductase 3, [RH, Score=571, Expect=0.0]} {Mouse: ENSMUSG00000000811, Txnrd3, thioredoxin reductase 3, [RH, Score=563, Expect=0.0]} {Dmel: FBgn0020653, Trxr-1, Thioredoxin reductase-1, [RH, Score=484, Expect=1e-166]} {Celegans: WBGene00015553, trxr-1, Thioredoxin reductase 1, [RH, Score=486, Expect=5e-165]} {Smed: dd_Smed_v6_960_0_1, dd_Smed_v6_960_0_1, [RH, Score=590, Expect=0.0]} {RNA1509_1268, RNA1509_4098, RNA1509_7641} {RNA1310_6460.1, RNA1509_1268, RNA1509_4098, RNA1509_7641} {RNA1509_1268, RNA1509_4098, RNA1509_7641, RNA815_2233}
89. MligTC455_15235 160 3.33 Mlig455_032913

Neo: -

Age: Up-Down-Up

1.687 - - - 0.951 - 0.736 Mlig455_032913 {REF} {Length: 1509} {RNA1509_47104, RNA1509_50252} {RNA1310_33122.2, RNA1509_50252} {RNA1509_50252, RNA815_20754}
90. MligTC455_34922 1849 38.53 Mlig455_030407, Mlig455_069030

Neo: -

Age: -

Region-enriched R5: 2.185/0.00224

1.685 - - - 0.967 - 0.718

Mlig455_030407 {REF} {Length: 991} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=23.1]} {RNA1509_26310} {RNA1310_62659} {RNA815_52108}

Mlig455_069030 {REF} {Length: 800} {RNA1509_26310} {RNA1310_62659} {RNA815_52108}
91. MligTC455_11650 1098 22.87 Mlig455_007133

Neo: -

Age: logFC(26M/2M)=1.455

Region-enriched R4: 2.055/0.00000
Region-enriched R3: 1.617/0.00001
Region-enriched R5: 1.032/0.00532

1.68 - - - - 0.728 0.952 Mlig455_007133 {REF} {Length: 1372} {Pfam: Tyrosine phosphatase family [PF13350.8, score=133.9]; Tyrosine phosphatase family [PF03162.15, score=32.8]} {Smed: dd_Smed_v6_6110_0_1, dd_Smed_v6_6110_0_1, [RH, Score=96.3, Expect=2e-22]} {RNA1509_24412} {RNA1310_29199} {RNA815_14210.1}
92. MligTC455_41002 233 4.84 Mlig455_022813

Neo: -

Age: -

PNPLA2 1.677 0.723 - - 0.954 - - Mlig455_022813 {REF} {Length: 4359} {TRANSSPLICED} {Pfam: Patatin-like phospholipase [PF01734.24, score=37.5]} {Human: ENSG00000177666, PNPLA2, patatin like phospholipase domain containing 2, [RH, Score=206, Expect=8e-59]} {Mouse: ENSMUSG00000025509, Pnpla2, patatin-like phospholipase domain containing 2, [RH, Score=203, Expect=4e-58]} {Dmel: FBgn0036449, bmm, brummer, [RH, Score=247, Expect=5e-74]} {Celegans: WBGene00015484, atgl-1, Patanin-like phospholipase domain-containing protein, [RH, Score=188, Expect=3e-51]} {Smed: dd_Smed_v6_9544_0_1, dd_Smed_v6_9544_0_1, [RH, Score=224, Expect=1e-65]} {RNA1509_22408, RNA1509_31645} {RNA1310_13835, RNA1509_22408, RNA1509_31645} {RNA1509_22408, RNA1509_31645, RNA815_4510}
93. MligTC455_41954 117 2.44 Mlig455_030295

Neo: -

Age: Up-Down-Up

1.669 - - - - 0.702 0.967 Mlig455_030295 {REF} {Length: 548} {NoTransDecoderORF} {RNA1509_38678} {RNA1310_19204} {RNA815_26429}
94. MligTC455_16722 2022 42.12 Mlig455_001580, Mlig455_060120

Neo: -

Age: -

SORT1 1.668 - - - 0.956 0.712 -

Mlig455_001580 {REF} {Length: 3841} {Pfam: Sortilin, neurotensin receptor 3, [PF15902.7, score=246.2]; Sortilin, neurotensin receptor 3, C-terminal [PF15901.7, score=88.9]; BNR/Asp-box repeat [PF02012.22, score=30.9]; BNR repeat-like domain [PF13088.8, score=18.1]} {Human: ENSG00000134243, SORT1, sortilin 1, [Score=328, Expect=7e-99]} {Mouse: ENSMUSG00000068747, Sort1, sortilin 1, [Score=335, Expect=2e-101]} {Smed: dd_Smed_v6_1666_0_1, dd_Smed_v6_1666_0_1, [Score=483, Expect=1e-158]} {RNA1509_1193, RNA1509_27254} {RNA1310_4487, RNA1509_27254} {RNA1509_27254, RNA815_1034}

Mlig455_060120 {REF} {Length: 4319} {Pfam: Sortilin, neurotensin receptor 3, [PF15902.7, score=247.3]; Sortilin, neurotensin receptor 3, C-terminal [PF15901.7, score=111.1]; BNR/Asp-box repeat [PF02012.22, score=30.6]} {Human: ENSG00000134243, SORT1, sortilin 1, [RH, Score=350, Expect=4e-107]} {Mouse: ENSMUSG00000068747, Sort1, sortilin 1, [RH, Score=363, Expect=4e-112]} {Smed: dd_Smed_v6_1666_0_1, dd_Smed_v6_1666_0_1, [RH, Score=514, Expect=1e-170]} {RNA1509_1193, RNA1509_9859} {RNA1310_4487, RNA1509_1193, RNA1509_9859} {RNA1509_1193, RNA1509_9859, RNA815_1034}
95. MligTC455_43973 885 18.45 Mlig455_009701

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.587

Region-enriched R3: 2.420/0.00013
Region-enriched R4: 2.368/0.00100
Region-enriched R5: 2.041/0.00084
Region-enriched R6: 1.815/0.03624

0.98 - - - - - 0.980 Mlig455_009701 {REF} {Length: 689} {RNA1509_31193, RNA1509_40156, RNA1509_53905} {RNA1310_57121, RNA1509_31193, RNA1509_40156, RNA1509_53905} {RNA1509_31193, RNA1509_40156, RNA1509_53905, RNA815_25444}
96. MligTC455_37947 220 4.59 Mlig455_052622

Neo: -

Age: logFC(26M/2M)=0.451

Region-enriched R3: 2.784/0.02131

0.974 - - - 0.974 - - Mlig455_052622 {REF} {Length: 1774} {RNA1509_54490} {RNA1310_14110, RNA1509_54490} {RNA1509_54490, RNA815_23203}
97. MligTC455_21581 10 0.21 Mlig455_032471

Neo: -

Age: -

0.973 - - - - - 0.973 Mlig455_032471 {REF} {Length: 1381} {Pfam: WSC domain [PF01822.21, score=36.5]} {RNA1310_78298} {RNA815_49767}
98. MligTC455_04596 69 1.43 Mlig455_030686

Neo: -

Age: Up-Down-Up

0.972 - - - - - 0.972 Mlig455_030686 {REF} {Length: 1197} {Pfam: NIPSNAP [PF07978.15, score=75.2]} {Mouse: ENSMUSG00000015247, Nipsnap3b, nipsnap homolog 3B, [RH, Score=73.9, Expect=1e-15]} {RNA1509_38571} {RNA1310_21189.1} {RNA815_13886}
99. MligTC455_18903 201 4.19 Mlig455_060398

Neo: -

Age: -

TMEM136 0.971 - - - 0.971 - - Mlig455_060398 {REF} {Length: 3213} {TRANSSPLICED} {Pfam: TLC domain [PF03798.18, score=62.1]} {Human: ENSG00000181264, TMEM136, transmembrane protein 136, [Score=117, Expect=4e-31]} {Mouse: ENSMUSG00000048503, Tmem136, transmembrane protein 136, [Score=115, Expect=1e-30]} {Smed: dd_Smed_v6_10466_0_2, dd_Smed_v6_10466_0_2, [Score=102, Expect=4e-26]} {RNA1509_51840, RNA1509_57769} {RNA1310_27654, RNA1509_57769} {RNA1509_57769, RNA815_12680}
100. MligTC455_12343 252 5.25 Mlig455_004664

Neo: Germline

Age: -

Region-enriched R4: 2.851/0.00071

0.97 - - - - - 0.970 Mlig455_004664 {REF} {Length: 1100} {Pfam: AMOP domain [PF03782.19, score=43.4]} {Dmel: FBgn0051004, mesh, [Score=46.6, Expect=1e-05]} {RNA1509_31294} {RNA1310_32024, RNA1509_31294} {RNA1509_31294, RNA815_16383}

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