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Results for MligTC455_28364

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_28364 467 9.73 Mlig455_061240, Mlig455_061241

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.355

Regeneration-upregulated R6: 2.218

Regeneration-enriched R6: 2.218

RTL1

Mlig455_061240 {REF} {Length: 5353} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=103.3]; 'Cold-shock' DNA-binding domain [PF00313.24, score=30.2]; Aspartyl protease [PF13650.8, score=21.9]; Zinc knuckle [PF13696.8, score=21.9]; Zinc knuckle [PF00098.25, score=21.6]; gag-polyprotein putative aspartyl protease [PF13975.8, score=21.3]; Aspartyl protease [PF09668.12, score=20.4]} {Human: ENSG00000254656, RTL1, retrotransposon Gag like 1, [Score=57.4, Expect=2e-07]} {Mouse: ENSMUSG00000033508, Asprv1, aspartic peptidase, retroviral-like 1, [Score=50.8, Expect=5e-06]} {Smed: dd_Smed_v6_1574_6_44, dd_Smed_v6_1574_6_44, [Score=203, Expect=8e-56]} {RNA1509_4878} {RNA1310_542.1} {RNA815_66.1}

Mlig455_061241 {REF} {Length: 5317} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=98.7]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=96.7]; Integrase core domain [PF00665.28, score=47.7]; Integrase zinc binding domain [PF17921.3, score=38.4]; H2C2 zinc finger [PF09337.12, score=19.5]} {Smed: dd_Smed_v6_1574_6_72, dd_Smed_v6_1574_6_72, [Score=147, Expect=7e-38]} {RNA1509_4878, RNA1509_55705} {RNA1310_542.1, RNA1509_55705} {RNA1509_55705, RNA815_7586}

Cumulative graph for MligTC455_28364

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.416 3.574 0.44867 1.00000
RegionR2 0.171 3.574 0.80834 1.00000
RegionR3 -0.332 3.574 0.56782 1.00000
RegionR4 -0.24 3.574 0.70845 0.99473
RegionR5 1.127 3.574 0.00828 0.05029
RegionR6 -0.24 3.574 0.68831 1.00000
RegionR7 0.625 3.574 0.39810 1.00000
RegionR8 0.305 3.574 0.76621 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 2.285 3.574 0.30040 0.99740
RegenerationR2 0.802 3.574 0.11838 0.53557
RegenerationR3 1.105 3.574 0.05915 0.41525
RegenerationR4 0.68 3.574 0.20749 0.65470
RegenerationR5 0.372 3.574 0.42173 0.81219
RegenerationR6 2.218 3.574 0.00005 0.00572 Specific for R6: 2.218
RegenerationBL 1.428 3.574 0.03045 0.19464
RegenerationTP -0.04 3.574 0.96109 1.00000


Genes with expression patterns similar to MligTC455_28364

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_28364 467 9.73 Mlig455_061240, Mlig455_061241

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.355

Regeneration-upregulated R6: 2.218

Regeneration-enriched R6: 2.218

RTL1 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_061240 {REF} {Length: 5353} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=103.3]; 'Cold-shock' DNA-binding domain [PF00313.24, score=30.2]; Aspartyl protease [PF13650.8, score=21.9]; Zinc knuckle [PF13696.8, score=21.9]; Zinc knuckle [PF00098.25, score=21.6]; gag-polyprotein putative aspartyl protease [PF13975.8, score=21.3]; Aspartyl protease [PF09668.12, score=20.4]} {Human: ENSG00000254656, RTL1, retrotransposon Gag like 1, [Score=57.4, Expect=2e-07]} {Mouse: ENSMUSG00000033508, Asprv1, aspartic peptidase, retroviral-like 1, [Score=50.8, Expect=5e-06]} {Smed: dd_Smed_v6_1574_6_44, dd_Smed_v6_1574_6_44, [Score=203, Expect=8e-56]} {RNA1509_4878} {RNA1310_542.1} {RNA815_66.1}

Mlig455_061241 {REF} {Length: 5317} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=98.7]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=96.7]; Integrase core domain [PF00665.28, score=47.7]; Integrase zinc binding domain [PF17921.3, score=38.4]; H2C2 zinc finger [PF09337.12, score=19.5]} {Smed: dd_Smed_v6_1574_6_72, dd_Smed_v6_1574_6_72, [Score=147, Expect=7e-38]} {RNA1509_4878, RNA1509_55705} {RNA1310_542.1, RNA1509_55705} {RNA1509_55705, RNA815_7586}
2. MligTC455_28362 852 17.75 Mlig455_031039, Mlig455_047027

Neo: -

Age: -

Region-enriched R5: 1.224/0.02131

Regeneration-upregulated R6: 2.337

Regeneration-enriched R6: 2.337

RTL1 5.78 0.975 0.974 0.913 0.968 0.966 0.984

Mlig455_031039 {REF} {Length: 9265} {TRANSSPLICED} {Pfam: 'Cold-shock' DNA-binding domain [PF00313.24, score=31.5]; Zinc knuckle [PF13696.8, score=23.2]; Zinc knuckle [PF00098.25, score=22.9]} {RNA1509_4878} {RNA1310_542.1} {RNA815_66.1}

Mlig455_047027 {REF} {Length: 9661} {TRANSSPLICED} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=102.5]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=102.1]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=95.4]; Integrase core domain [PF00665.28, score=46.7]; Integrase zinc binding domain [PF17921.3, score=36.9]; 'Cold-shock' DNA-binding domain [PF00313.24, score=29.1]; Zinc knuckle [PF13696.8, score=21.3]; Zinc knuckle [PF00098.25, score=20.8]; Aspartyl protease [PF13650.8, score=20.8]; gag-polyprotein putative aspartyl protease [PF13975.8, score=20.4]; H2C2 zinc finger [PF09337.12, score=19.7]; Aspartyl protease [PF09668.12, score=19.1]} {Human: ENSG00000254656, RTL1, retrotransposon Gag like 1, [Score=99.4, Expect=5e-20]} {Mouse: ENSMUSG00000033508, Asprv1, aspartic peptidase, retroviral-like 1, [Score=50.8, Expect=1e-05]} {Smed: dd_Smed_v6_1574_6_43, dd_Smed_v6_1574_6_43, [Score=317, Expect=3e-94]} {RNA1509_4878} {RNA1310_542.1} {RNA815_66.1}
3. MligTC455_28361 440 9.16 Mlig455_040638

Neo: Int S/G2/M

Age: -

Region-enriched R5: 1.191/0.01323

Regeneration-upregulated R6: 2.081

Regeneration-enriched R6: 2.081

RTL1 5.71 0.899 0.947 0.976 0.927 0.984 0.977 Mlig455_040638 {REF} {Length: 10716} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=102.8]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=102.1]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=95.3]; Integrase core domain [PF00665.28, score=46.4]; Integrase zinc binding domain [PF17921.3, score=36.9]; 'Cold-shock' DNA-binding domain [PF00313.24, score=29.1]; Zinc knuckle [PF13696.8, score=21.2]; Zinc knuckle [PF00098.25, score=20.9]; Aspartyl protease [PF13650.8, score=20.8]; gag-polyprotein putative aspartyl protease [PF13975.8, score=20.4]; H2C2 zinc finger [PF09337.12, score=19.7]; Aspartyl protease [PF09668.12, score=19.1]} {Human: ENSG00000254656, RTL1, retrotransposon Gag like 1, [Score=99.8, Expect=4e-20]} {Mouse: ENSMUSG00000033508, Asprv1, aspartic peptidase, retroviral-like 1, [Score=50.8, Expect=9e-06]} {Smed: dd_Smed_v6_1574_6_43, dd_Smed_v6_1574_6_43, [Score=317, Expect=3e-94]} {RNA1509_4878} {RNA1310_542.1} {RNA815_66.1}
4. MligTC455_28365 270 5.63 Mlig455_068689

Neo: -

Age: Up-Down-Down

Region-enriched R5: 1.758/0.01074

RTL1 5.588 0.915 0.937 0.869 0.956 0.940 0.971 Mlig455_068689 {REF} {Length: 9784} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=102.8]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=100.7]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=95.3]; Integrase core domain [PF00665.28, score=46.4]; Integrase zinc binding domain [PF17921.3, score=35.6]; 'Cold-shock' DNA-binding domain [PF00313.24, score=29.6]; Zinc knuckle [PF13696.8, score=21.3]; Zinc knuckle [PF00098.25, score=20.8]; Aspartyl protease [PF13650.8, score=20.8]; gag-polyprotein putative aspartyl protease [PF13975.8, score=20.4]; Aspartyl protease [PF09668.12, score=19.1]} {Human: ENSG00000254656, RTL1, retrotransposon Gag like 1, [Score=99.4, Expect=5e-20]} {Mouse: ENSMUSG00000033508, Asprv1, aspartic peptidase, retroviral-like 1, [Score=50.8, Expect=9e-06]} {Smed: dd_Smed_v6_1574_6_43, dd_Smed_v6_1574_6_43, [Score=317, Expect=2e-94]} {RNA1509_4878} {RNA1310_542.1} {RNA815_66.1}
5. MligTC455_40048 1373 28.61 Mlig455_000540

Neo: Int S/G2/M

Age: Down-Up-Up

Region-enriched R5: 1.231/0.00009

Regeneration-upregulated BL: 1.427

Regeneration-enriched BL: 1.427

THOC7 1.668 - - 0.705 0.963 - - Mlig455_000540 {REF} {Length: 1040} {TRANSSPLICED} {Pfam: Tho complex subunit 7 [PF05615.15, score=79.2]} {Human: ENSG00000163634, THOC7, THO complex 7, [RH, Score=95.9, Expect=6e-24]} {Mouse: ENSMUSG00000053453, Thoc7, THO complex 7, [RH, Score=95.9, Expect=4e-24]} {Dmel: FBgn0035110, thoc7, [RH, Score=73.2, Expect=4e-15]} {Smed: dd_Smed_v6_3428_0_1, dd_Smed_v6_3428_0_1, [RH, Score=121, Expect=2e-34]} {RNA1509_27604} {RNA1310_25169, RNA1509_27604} {RNA1509_27604, RNA815_13958}
6. MligTC455_51907 257 5.35 Mlig455_014250

Neo: -

Age: -

SYAP1 0.978 - - - - 0.978 - Mlig455_014250 {REF} {Length: 1884} {TRANSSPLICED} {Pfam: BSD domain [PF03909.19, score=47.8]} {Human: ENSG00000169895, SYAP1, synapse associated protein 1, [RH, Score=106, Expect=3e-26]} {Mouse: ENSMUSG00000031357, Syap1, synapse associated protein 1, [RH, Score=109, Expect=2e-27]} {Dmel: FBgn0013334, Sap47, Synapse-associated protein 47kD, [Score=103, Expect=1e-25]} {Celegans: WBGene00007621, C16C2.4, [Score=81.6, Expect=9e-18]} {Smed: dd_Smed_v6_1295_0_1, dd_Smed_v6_1295_0_1, [RH, Score=89.7, Expect=7e-21]} {RNA1509_28343, RNA1509_31173, RNA1509_46934, RNA1509_60128} {RNA1310_21856, RNA1509_28343, RNA1509_31173, RNA1509_46934, RNA1509_60128} {RNA1509_28343, RNA1509_31173, RNA1509_46934, RNA1509_60128, RNA815_15095}
7. MligTC455_47816 659 13.73 Mlig455_041971

Neo: Int S/G2/M

Age: -

MYEF2 0.976 - - - 0.976 - - Mlig455_041971 {REF} {Length: 3455} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=139.1]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF13893.8, score=23.2]; RNA binding motif [PF08777.13, score=19.9]} {Human: ENSG00000104177, MYEF2, myelin expression factor 2, [RH, Score=124, Expect=2e-30]} {Mouse: ENSMUSG00000027201, Myef2, myelin basic protein expression factor 2, repressor, [RH, Score=120, Expect=5e-29]; ENSMUSG00000049230, Gm9833, predicted gene 9833, [RH, Score=120, Expect=3e-29]} {Dmel: FBgn0267790, rump, rumpelstiltskin, [RH, Score=117, Expect=5e-28]} {Celegans: WBGene00007706, C25A1.4, [RH, Score=104, Expect=3e-24]} {Smed: dd_Smed_v6_2707_0_1, dd_Smed_v6_2707_0_1, [RH, Score=155, Expect=5e-42]} {RNA1509_26000} {RNA1310_2998.1} {RNA815_978}
8. MligTC455_15737 168 3.51 Mlig455_069550

Neo: -

Age: logFC(26M/2M)=0.762

SGMS1 0.957 - - - - 0.957 - Mlig455_069550 {REF} {Length: 2417} {Pfam: PAP2 superfamily C-terminal [PF14360.8, score=83.5]} {Human: ENSG00000198964, SGMS1, sphingomyelin synthase 1, [RH, Score=210, Expect=1e-62]} {Mouse: ENSMUSG00000040451, Sgms1, sphingomyelin synthase 1, [RH, Score=207, Expect=1e-61]; ENSMUSG00000050931, Sgms2, sphingomyelin synthase 2, [RH, Score=201, Expect=5e-60]; ENSMUSG00000116143, Sgms2, sphingomyelin synthase 2, [RH, Score=201, Expect=5e-60]} {Dmel: FBgn0052380, SMSr, [RH, Score=171, Expect=1e-46]} {Celegans: WBGene00004892, sms-1, Phosphatidylcholine:ceramide cholinephosphotransferase 1, [RH, Score=201, Expect=7e-59]} {Smed: dd_Smed_v6_11976_0_2, dd_Smed_v6_11976_0_2, [RH, Score=167, Expect=5e-47]} {RNA1509_21942} {RNA1310_9001} {RNA815_13690}
9. MligTC455_52256 1195 24.9 Mlig455_045130, Mlig455_045164

Neo: -

Age: -

SPG21 0.956 - - - - - 0.956

Mlig455_045130 {REF} {Length: 2055} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=26.0]; Alpha/beta hydrolase family [PF12697.9, score=20.4]; Thioesterase domain [PF00975.22, score=19.6]} {Human: ENSG00000090487, SPG21, SPG21, maspardin, [Score=317, Expect=2e-107]} {Mouse: ENSMUSG00000032388, Spg21, SPG21, maspardin, [Score=316, Expect=2e-107]} {Smed: dd_Smed_v6_4182_0_1, dd_Smed_v6_4182_0_1, [Score=303, Expect=1e-102]} {RNA1509_18282} {RNA1310_12279} {RNA815_31704}

Mlig455_045164 {REF} {Length: 2194} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=26.3]; Serine aminopeptidase, S33 [PF12146.10, score=22.0]; Alpha/beta hydrolase family [PF12697.9, score=21.8]} {Human: ENSG00000090487, SPG21, SPG21, maspardin, [RH, Score=342, Expect=5e-117]} {Mouse: ENSMUSG00000032388, Spg21, SPG21, maspardin, [RH, Score=341, Expect=6e-117]} {Smed: dd_Smed_v6_4182_0_1, dd_Smed_v6_4182_0_1, [RH, Score=322, Expect=1e-109]} {RNA1509_18282} {RNA1310_12279} {RNA815_15404}
10. MligTC455_48822 452 9.42 Mlig455_008826, Mlig455_008931

Neo: Irradiation

Age: -

Region-enriched R5: 1.925/0.04975

Regeneration-enriched R6: 4.526
Regeneration-enriched BL: 3.730

TNK2 0.952 - - - - 0.952 -

Mlig455_008826 {REF} {Length: 2869} {Pfam: UBA-like domain [PF14555.8, score=27.3]} {Human: ENSG00000061938, TNK2, tyrosine kinase non receptor 2, [RH, Score=69.7, Expect=1e-12]} {Mouse: ENSMUSG00000022791, Tnk2, tyrosine kinase, non-receptor, 2, [RH, Score=70.1, Expect=8e-13]} {RNA1310_31670} {RNA815_33665}

Mlig455_008931 {REF} {Length: 3044} {Pfam: UBA-like domain [PF14555.8, score=28.7]} {Human: ENSG00000061938, TNK2, tyrosine kinase non receptor 2, [RH, Score=70.9, Expect=6e-13]} {Mouse: ENSMUSG00000022791, Tnk2, tyrosine kinase, non-receptor, 2, [RH, Score=70.9, Expect=4e-13]} {RNA1310_31670} {RNA815_33665}

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