Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_29106 | 442 | 9.20 | Mlig455_064655 | Neo: - Age: Up-Down-Down Region-specific R7: 3.413 Region-enriched R7: 3.335/0.00000 Regeneration-downregulated BL: -6.699 Regeneration-depleted BL: -6.699 |
FNDC3A | Mlig455_064655 {REF} {Length: 4196} {Pfam: Fibronectin type III domain [PF00041.23, score=113.8]; Purple acid Phosphatase, N-terminal domain [PF16656.7, score=40.4]; SusE outer membrane protein [PF14292.8, score=22.6]; Fibronectin-III type domain [PF16794.7, score=18.7]} {Human: ENSG00000102531, FNDC3A, fibronectin type III domain containing 3A, [Score=154, Expect=4e-40]; ENSG00000075420, FNDC3B, fibronectin type III domain containing 3B, [Score=147, Expect=5e-38]} {Mouse: ENSMUSG00000033487, Fndc3a, fibronectin type III domain containing 3A, [Score=151, Expect=2e-39]} {Dmel: FBgn0259735, CG42389, [Score=99.8, Expect=4e-22]} {Celegans: WBGene00006776, unc-40, Unc-40 protein, [Score=63.9, Expect=1e-10]} {Smed: dd_Smed_v6_4612_0_2, dd_Smed_v6_4612_0_2, [Score=140, Expect=8e-36]} {RNA1509_7286} {RNA1310_921.1} {RNA815_21055} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -3.478 | 3.379 | 0.02465 | 0.41719 | |
RegionR2 | 2.018 | 3.379 | 0.00045 | 0.01230 | |
RegionR3 | -0.659 | 3.379 | 0.24157 | 0.78319 | |
RegionR4 | -1.778 | 3.379 | 0.01431 | 0.07964 | |
RegionR5 | -1.842 | 3.379 | 0.00857 | 0.05162 | |
RegionR6 | 0.707 | 3.379 | 0.11982 | 0.63092 | |
RegionR7 | 3.335 | 3.379 | 0.00000 | 0.00000 | Specific for R7: 3.413 |
RegionR8 | 1.695 | 3.379 | 0.00624 | 0.14383 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -1.976 | 3.379 | 0.73806 | 1.00000 | |
RegenerationR2 | -0.166 | 3.379 | 0.73524 | 0.96787 | |
RegenerationR3 | 1.168 | 3.379 | 0.04989 | 0.38721 | |
RegenerationR4 | 0.514 | 3.379 | 0.40780 | 0.81890 | |
RegenerationR5 | 1.249 | 3.379 | 0.02946 | 0.28851 | |
RegenerationR6 | -2.151 | 3.379 | 0.00618 | 0.09552 | |
RegenerationBL | -6.699 | 3.379 | 0.00009 | 0.00431 | Specific for BL: -6.699 |
RegenerationTP | -1.021 | 3.379 | 0.10675 | 0.50490 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_29106 | 442 | 9.2 | Mlig455_064655 | Neo: - Age: Up-Down-Down Region-specific R7: 3.413 Region-enriched R7: 3.335/0.00000 Regeneration-downregulated BL: -6.699 Regeneration-depleted BL: -6.699 |
FNDC3A | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_064655 {REF} {Length: 4196} {Pfam: Fibronectin type III domain [PF00041.23, score=113.8]; Purple acid Phosphatase, N-terminal domain [PF16656.7, score=40.4]; SusE outer membrane protein [PF14292.8, score=22.6]; Fibronectin-III type domain [PF16794.7, score=18.7]} {Human: ENSG00000102531, FNDC3A, fibronectin type III domain containing 3A, [Score=154, Expect=4e-40]; ENSG00000075420, FNDC3B, fibronectin type III domain containing 3B, [Score=147, Expect=5e-38]} {Mouse: ENSMUSG00000033487, Fndc3a, fibronectin type III domain containing 3A, [Score=151, Expect=2e-39]} {Dmel: FBgn0259735, CG42389, [Score=99.8, Expect=4e-22]} {Celegans: WBGene00006776, unc-40, Unc-40 protein, [Score=63.9, Expect=1e-10]} {Smed: dd_Smed_v6_4612_0_2, dd_Smed_v6_4612_0_2, [Score=140, Expect=8e-36]} {RNA1509_7286} {RNA1310_921.1} {RNA815_21055} |
2. | MligTC455_29107 | 447 | 9.32 | Mlig455_064688 | Neo: - Age: Up-Down-Down Region-specific R7: 3.414 Region-enriched R7: 3.290/0.00000 Regeneration-downregulated BL: -6.721 Regeneration-depleted BL: -6.721 |
FNDC3A | 5.795 | 0.999 | 0.998 | 0.999 | 1.000 | 0.841 | 0.958 | Mlig455_064688 {REF} {Length: 8899} {TRANSSPLICED} {Pfam: Fibronectin type III domain [PF00041.23, score=236.6]; Purple acid Phosphatase, N-terminal domain [PF16656.7, score=74.4]} {Human: ENSG00000102531, FNDC3A, fibronectin type III domain containing 3A, [Score=310, Expect=3e-87]} {Mouse: ENSMUSG00000033487, Fndc3a, fibronectin type III domain containing 3A, [Score=301, Expect=3e-84]} {Dmel: FBgn0259735, CG42389, [Score=159, Expect=5e-39]} {Celegans: WBGene00006759, unc-22, Twitchin, [Score=111, Expect=3e-24]} {Smed: dd_Smed_v6_4612_0_1, dd_Smed_v6_4612_0_1, [Score=284, Expect=4e-78]} {RNA1509_44310, RNA1509_7286, RNA1509_7535} {RNA1310_921.1, RNA1509_44310, RNA1509_7286, RNA1509_7535} {RNA1509_44310, RNA1509_7286, RNA1509_7535, RNA815_7086} |
3. | MligTC455_42454 | 1804 | 37.58 | Mlig455_044488 | Neo: - Age: - Region-enriched R7: 3.309/0.00000 Regeneration-downregulated BL: -5.601 Regeneration-depleted BL: -5.601 |
2.662 | 0.899 | 0.966 | - | 0.797 | - | - | Mlig455_044488 {REF} {Length: 3520} {Pfam: Domain of unknown function (DUF4735) [PF15882.7, score=197.2]} {Smed: dd_Smed_v6_21285_0_1, dd_Smed_v6_21285_0_1, [RH, Score=209, Expect=9e-65]} {RNA1509_24134} {RNA1310_20974} {RNA815_11272} | |
4. | MligTC455_40142 | 75 | 1.57 | Mlig455_022108 | Neo: - Age: - |
RAB37 | 1.79 | - | - | - | 0.837 | 0.953 | - | Mlig455_022108 {REF} {Length: 1460} {Pfam: Ras family [PF00071.24, score=174.5]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=101.6]; ADP-ribosylation factor family [PF00025.23, score=48.9]; 50S ribosome-binding GTPase [PF01926.25, score=23.6]} {Human: ENSG00000172794, RAB37, RAB37, member RAS oncogene family, [RH, Score=204, Expect=8e-66]; ENSG00000167964, RAB26, RAB26, member RAS oncogene family, [RH, Score=197, Expect=7e-62]} {Mouse: ENSMUSG00000020732, Rab37, RAB37, member RAS oncogene family, [RH, Score=202, Expect=2e-64]; ENSMUSG00000079657, Rab26, RAB26, member RAS oncogene family, [RH, Score=197, Expect=4e-62]} {Dmel: FBgn0086913, Rab26, [Score=187, Expect=7e-57]} {Celegans: WBGene00004285, rab-37, RAB family, [Score=166, Expect=1e-50]} {Smed: dd_Smed_v6_3485_0_1, dd_Smed_v6_3485_0_1, [Score=169, Expect=4e-52]} {RNA1310_81029} {RNA815_42257} |
5. | MligTC455_25793 | 109 | 2.26 | Mlig455_051834 | Neo: - Age: - |
1.715 | - | - | 0.756 | - | 0.959 | - | Mlig455_051834 {REF} {Length: 928} {RNA1509_22707} {RNA1310_61401.2} {RNA815_24119.1} | |
6. | MligTC455_17192 | 43 | 0.89 | Mlig455_060323 | Neo: - Age: - |
1.701 | - | - | - | - | 0.969 | 0.732 | Mlig455_060323 {REF} {Length: 504} {NoTransDecoderORF} {RNA1310_129337} | |
7. | MligTC455_30093 | 165 | 3.43 | Mlig455_006983 | Neo: - |
1.687 | - | - | - | 0.730 | - | 0.957 | Mlig455_006983 {REF} {Length: 1958} {Pfam: Rel homology DNA-binding domain [PF00554.24, score=60.6]; Uncharacterised protein family (UPF0172) [PF03665.15, score=18.8]} {RNA1509_55534} {RNA1310_1280.1} {RNA815_6392} | |
8. | MligTC455_13293 | 364 | 7.59 | Mlig455_012562 | Neo: - Age: Down-Up-Down |
FYN | 0.98 | - | - | - | - | - | 0.980 | Mlig455_012562 {REF} {Length: 2323} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=272.2]; Protein kinase domain [PF00069.27, score=145.0]; SH2 domain [PF00017.26, score=47.5]; SH3 domain [PF00018.30, score=43.5]; Variant SH3 domain [PF07653.19, score=29.7]; Variant SH3 domain [PF14604.8, score=29.4]; Haspin like kinase domain [PF12330.10, score=21.4]; ABC1 atypical kinase-like domain [PF03109.18, score=18.6]} {Human: ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=366, Expect=8e-121]; ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=364, Expect=1e-120]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=357, Expect=5e-118]; ENSG00000176105, YES1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=357, Expect=2e-117]; ENSG00000197122, SRC, SRC proto-oncogene, non-receptor tyrosine kinase, [Score=352, Expect=2e-115]} {Mouse: ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=369, Expect=3e-122]; ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=365, Expect=6e-121]; ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=357, Expect=2e-117]; ENSMUSG00000027646, Src, Rous sarcoma oncogene, [Score=352, Expect=1e-115]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=361, Expect=1e-119]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=379, Expect=4e-127]} {Smed: dd_Smed_v6_3363_0_2, dd_Smed_v6_3363_0_2, [Score=431, Expect=1e-147]} {RNA1509_28839} {RNA1310_8178.1} {RNA815_4079.1} |
9. | MligTC455_42324 | 673 | 14.02 | Mlig455_056179, Mlig455_056186 | Neo: - Age: Down-Down-Up |
0.968 | - | - | - | - | 0.968 | - | Mlig455_056179 {REF} {Length: 1288} {RNA1509_43486} {RNA1310_37291.2} {RNA815_18345} Mlig455_056186 {REF} {Length: 979} {RNA1509_43486} {RNA1310_37291.1, RNA1509_43486} {RNA1509_43486, RNA815_18345} |
|
10. | MligTC455_49338 | 92 | 1.92 | Mlig455_019714 | Neo: - Age: - Region-enriched R2: 3.827/0.02214 |
CA7 | 0.962 | - | 0.962 | - | - | - | - | Mlig455_019714 {REF} {Length: 2496} {Pfam: Eukaryotic-type carbonic anhydrase [PF00194.23, score=207.6]} {Human: ENSG00000168748, CA7, carbonic anhydrase 7, [Score=157, Expect=2e-45]} {Mouse: ENSMUSG00000031883, Car7, carbonic anhydrase 7, [Score=156, Expect=3e-45]} {Dmel: FBgn0027844, CAH1, Carbonic anhydrase 1, [Score=129, Expect=8e-35]} {Celegans: WBGene00000283, cah-5, Putative carbonic anhydrase 5, [Score=89.0, Expect=6e-20]} {Smed: dd_Smed_v6_11683_0_1, dd_Smed_v6_11683_0_1, [Score=159, Expect=4e-46]} {RNA1509_43765} {RNA1310_22186, RNA1509_43765} {RNA1509_43765, RNA815_18428} |
11. | MligTC455_20016 | 607 | 12.65 | Mlig455_041914 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=0.404 Region-enriched R2: 5.008/0.00002 |
0.961 | - | - | - | - | 0.961 | - | Mlig455_041914 {REF} {Length: 745} {Pfam: EF-hand domain [PF13405.8, score=60.3]; EF hand [PF00036.34, score=52.6]; EF-hand domain pair [PF13499.8, score=49.5]; EF hand [PF13202.8, score=40.2]; EF-hand domain [PF14658.8, score=30.6]; EF-hand domain pair [PF13833.8, score=30.2]} {Dmel: FBgn0052103, CG32103, [Score=43.5, Expect=1e-05]} {Smed: dd_Smed_v6_16347_0_2, dd_Smed_v6_16347_0_2, [Score=67.8, Expect=1e-15]} {RNA1509_17125, RNA1509_40839} {RNA1310_56976, RNA1509_40839} {RNA1509_40839, RNA815_29327} | |
12. | MligTC455_39126 | 319 | 6.64 | Mlig455_039302, Mlig455_054473, Mlig455_068598 | Neo: - Age: Up-Down-Down |
GIPC1 | 0.956 | - | - | 0.956 | - | - | - | Mlig455_039302 {REF} {Length: 3377} {Pfam: PDZ domain [PF00595.26, score=33.4]; PDZ domain [PF17820.3, score=18.9]} {Human: ENSG00000123159, GIPC1, GIPC PDZ domain containing family member 1, [Score=281, Expect=2e-93]} {Mouse: ENSMUSG00000019433, Gipc1, GIPC PDZ domain containing family, member 1, [Score=283, Expect=3e-94]} {Dmel: FBgn0010504, kermit, [Score=300, Expect=6e-101]} {Celegans: WBGene00016440, gipc-1, GIPC (RGS-GAIP Interacting Protein C) homolog, [Score=182, Expect=6e-55]} {Smed: dd_Smed_v6_5847_0_2, dd_Smed_v6_5847_0_2, [Score=280, Expect=3e-93]} {RNA1509_30159} {RNA1310_22067} {RNA815_21783} Mlig455_054473 {REF} {Length: 262} {NoTransDecoderORF} {RNA1509_30159} {RNA1310_22067} {RNA815_20472} Mlig455_068598 {REF} {Length: 984} {Pfam: Domain of unknown function (DUF4537) [PF15057.8, score=21.4]} {RNA1509_49822} {RNA1310_49394} {RNA815_51942} |
13. | MligTC455_39122 | 298 | 6.21 | Mlig455_054444 | Neo: - Age: - |
GIPC2 | 0.953 | - | - | 0.953 | - | - | - | Mlig455_054444 {REF} {Length: 2641} {Human: ENSG00000137960, GIPC2, GIPC PDZ domain containing family member 2, [Score=48.9, Expect=8e-07]; ENSG00000123159, GIPC1, GIPC PDZ domain containing family member 1, [Score=47.8, Expect=4e-07]} {Mouse: ENSMUSG00000019433, Gipc1, GIPC PDZ domain containing family, member 1, [Score=46.6, Expect=3e-06]} {Dmel: FBgn0010504, kermit, [Score=59.7, Expect=6e-11]} {Smed: dd_Smed_v6_5847_0_2, dd_Smed_v6_5847_0_2, [Score=47.4, Expect=7e-07]} {RNA1509_49145} {RNA1310_44032} {RNA815_21783} |
14. | MligTC455_05326 | 69 | 1.45 | Mlig455_064642 | Neo: - Age: Down-Up-Up Region-enriched R2: 8.953/0.00001 |
0.95 | - | - | - | - | 0.950 | - | Mlig455_064642 {REF} {Length: 1359} {NoTransDecoderORF} {RNA1509_35042} {RNA1310_28854} {RNA815_34103} |