M. lignano Tomo-Seq
Mlig455 transcriptome Search Regeneration Regions Sections Download

Data search


search
Exact
Search

Results for MligTC455_29517

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_29517 224 4.66 Mlig455_029414

Neo: -

Age: -

Region-enriched R4: 1.973/0.03463

 GRIA2 Mlig455_029414 {REF} {Length: 4533} {Pfam: Ligand-gated ion channel [PF00060.28, score=102.7]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=60.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=22.3]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=156, Expect=9e-39]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=155, Expect=2e-38]; ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=154, Expect=5e-38]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=152, Expect=2e-37]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=156, Expect=6e-39]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=155, Expect=2e-38]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=153, Expect=7e-38]} {Dmel: FBgn0038837, CG3822, [Score=148, Expect=1e-36]} {Celegans: WBGene00001615, glr-4, GLutamate Receptor family (AMPA), [Score=132, Expect=1e-31]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=234, Expect=8e-70]} {RNA1509_31776} {RNA1310_7321.1} {RNA815_2521.1}

Cumulative graph for MligTC455_29517

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -2.796 2.666 0.09460 0.65714
RegionR2 -0.171 2.666 0.84268 1.00000
RegionR3 -0.304 2.666 0.68742 1.00000
RegionR4 1.973 2.666 0.00471 0.03463
RegionR5 -0.137 2.666 0.81727 1.00000
RegionR6 0.894 2.666 0.20376 0.77759
RegionR7 0.878 2.666 0.29588 0.93088
RegionR8 -0.338 2.666 0.80156 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -5.062 2.666 0.40628 1.00000
RegenerationR2 1.246 2.666 0.01453 0.19743
RegenerationR3 0.96 2.666 0.16325 0.59785
RegenerationR4 0.11 2.666 0.86735 1.00000
RegenerationR5 0.349 2.666 0.60480 0.91199
RegenerationR6 0.303 2.666 0.64608 0.89651
RegenerationBL 0.18 2.666 0.81745 1.00000
RegenerationTP -0.409 2.666 0.66480 0.99674


Genes with expression patterns similar to MligTC455_29517

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_29517 224 4.66 Mlig455_029414

Neo: -

Age: -

Region-enriched R4: 1.973/0.03463

 GRIA2 5 1.000 - 1.000 1.000 1.000 1.000 Mlig455_029414 {REF} {Length: 4533} {Pfam: Ligand-gated ion channel [PF00060.28, score=102.7]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=60.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=22.3]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=156, Expect=9e-39]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=155, Expect=2e-38]; ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=154, Expect=5e-38]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=152, Expect=2e-37]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=156, Expect=6e-39]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=155, Expect=2e-38]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=153, Expect=7e-38]} {Dmel: FBgn0038837, CG3822, [Score=148, Expect=1e-36]} {Celegans: WBGene00001615, glr-4, GLutamate Receptor family (AMPA), [Score=132, Expect=1e-31]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=234, Expect=8e-70]} {RNA1509_31776} {RNA1310_7321.1} {RNA815_2521.1}
2. MligTC455_25075 1655 34.48 Mlig455_032530, Mlig455_037924

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.389

 1.859 - - 0.899 0.960 - -

Mlig455_032530 {REF} {Length: 2059} {Smed: dd_Smed_v6_8141_0_1, dd_Smed_v6_8141_0_1, [Score=86.7, Expect=4e-23]} {RNA1509_754} {RNA1310_11670} {RNA815_1893.1}

Mlig455_037924 {REF} {Length: 2155} {Smed: dd_Smed_v6_8141_0_1, dd_Smed_v6_8141_0_1, [Score=86.7, Expect=4e-23]} {RNA1509_12532, RNA1509_25934, RNA1509_59920, RNA1509_754} {RNA1310_11670, RNA1509_12532, RNA1509_25934, RNA1509_59920} {RNA1509_12532, RNA1509_25934, RNA1509_59920, RNA815_1893.1}
3. MligTC455_46399 80 1.66 Mlig455_022117

Neo: -

Age: Up-Up-Down

 1.831 - - - - 0.979 0.852 Mlig455_022117 {REF} {Length: 1088} {TRANSSPLICED} {RNA1310_7748.1} {RNA815_21787}
4. MligTC455_45196 415 8.66 Mlig455_012327

Neo: -

Age: logFC(26M/2M)=-0.373

 INVS 1.829 - - - 0.869 0.960 - Mlig455_012327 {REF} {Length: 3620} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=130.7]; Ankyrin repeats (many copies) [PF13637.8, score=103.5]; Ankyrin repeats (many copies) [PF13857.8, score=90.3]; Ankyrin repeat [PF13606.8, score=74.3]; Ankyrin repeat [PF00023.32, score=60.1]} {Human: ENSG00000119509, INVS, inversin, [Score=114, Expect=3e-25]; ENSG00000065413, ANKRD44, ankyrin repeat domain 44, [Score=111, Expect=9e-25]; ENSG00000139645, ANKRD52, ankyrin repeat domain 52, [Score=110, Expect=6e-24]} {Mouse: ENSMUSG00000014498, Ankrd52, ankyrin repeat domain 52, [Score=107, Expect=3e-23]; ENSMUSG00000052331, Ankrd44, ankyrin repeat domain 44, [Score=107, Expect=2e-23]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=104, Expect=4e-22]; ENSMUSG00000014496, Ankrd28, ankyrin repeat domain 28, [Score=103, Expect=5e-22]; ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=102, Expect=2e-21]} {Dmel: FBgn0260487, CG42534, [Score=112, Expect=6e-25]} {Celegans: WBGene00021304, nphp-2, NePHronoPhthisis (Human kidney disease) homolog, [Score=99.0, Expect=5e-21]} {Smed: dd_Smed_v6_16174_0_1, dd_Smed_v6_16174_0_1, [Score=115, Expect=3e-26]} {RNA1509_13535, RNA1509_36786} {RNA1310_5307.1, RNA1509_36786} {RNA1509_36786, RNA815_942}
5. MligTC455_51207 1231 25.65 Mlig455_019925, Mlig455_047946

Neo: -

Age: -

 MCTP1 1.81 - - 0.951 - 0.859 -

Mlig455_019925 {REF} {Length: 6036} {TRANSSPLICED} {Pfam: C2 domain [PF00168.32, score=305.3]} {Human: ENSG00000175471, MCTP1, multiple C2 and transmembrane domain containing 1, [Score=117, Expect=6e-26]} {Mouse: ENSMUSG00000032776, Mctp2, multiple C2 domains, transmembrane 2, [Score=114, Expect=4e-25]; ENSMUSG00000021596, Mctp1, multiple C2 domains, transmembrane 1, [Score=111, Expect=3e-24]} {Dmel: FBgn0034389, Mctp, Multiple C2 domain and transmembrane region protein, [Score=78.2, Expect=4e-14]} {Celegans: WBGene00004922, snt-2, Synaptotagmin 2, [Score=64.7, Expect=2e-10]} {Smed: dd_Smed_v6_13224_0_1, dd_Smed_v6_13224_0_1, [RH, Score=158, Expect=4e-39]} {RNA1509_4129} {RNA1310_1165.1} {RNA815_1160}

Mlig455_047946 {REF} {Length: 6306} {TRANSSPLICED} {Pfam: C2 domain [PF00168.32, score=305.4]} {Human: ENSG00000175471, MCTP1, multiple C2 and transmembrane domain containing 1, [Score=116, Expect=1e-25]} {Mouse: ENSMUSG00000021596, Mctp1, multiple C2 domains, transmembrane 1, [Score=111, Expect=4e-24]; ENSMUSG00000032776, Mctp2, multiple C2 domains, transmembrane 2, [Score=109, Expect=2e-23]} {Dmel: FBgn0039900, Syt7, Synaptotagmin 7, [Score=70.9, Expect=2e-12]} {Celegans: WBGene00004923, snt-3, SyNapTotagmin, [Score=68.2, Expect=7e-12]} {Smed: dd_Smed_v6_13224_0_1, dd_Smed_v6_13224_0_1, [RH, Score=158, Expect=4e-39]} {RNA1509_4129} {RNA1310_1165.1} {RNA815_1160}
6. MligTC455_30309 841 17.51 Mlig455_029677

Neo: -

Age: logFC(26M/2M)=-0.331

 CASP7 1.735 - - - 0.781 0.954 - Mlig455_029677 {REF} {Length: 3720} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=143.2]; Ankyrin repeats (many copies) [PF13637.8, score=117.0]; Caspase domain [PF00656.24, score=107.2]; Ankyrin repeat [PF00023.32, score=78.6]; Ankyrin repeats (many copies) [PF13857.8, score=77.0]; Ankyrin repeat [PF13606.8, score=70.6]; Baculovirus polyhedron envelope protein, PEP, N terminus [PF04512.14, score=24.1]; L27_2 [PF09045.12, score=19.1]} {Human: ENSG00000165806, CASP7, caspase 7, [Score=115, Expect=2e-27]; ENSG00000003400, CASP10, caspase 10, [Score=114, Expect=7e-26]; ENSG00000164305, CASP3, caspase 3, [Score=111, Expect=1e-26]} {Mouse: ENSMUSG00000025076, Casp7, caspase 7, [Score=114, Expect=1e-27]} {Dmel: FBgn0028381, Decay, Death executioner caspase related to Apopain/Yama, [Score=80.9, Expect=3e-16]} {Celegans: WBGene00000819, csp-1, Caspase A Caspase A subunit p16 Caspase A subunit p14, [Score=73.9, Expect=3e-14]} {Smed: dd_Smed_v6_1167_0_1, dd_Smed_v6_1167_0_1, [Score=121, Expect=8e-31]} {RNA1509_18682, RNA1509_35845} {RNA1310_39251, RNA1509_18682} {RNA1509_18682, RNA815_2803.1}
7. MligTC455_39860 56 1.17 Mlig455_046932

Neo: -

Age: -

 1.728 - - - 0.774 0.954 - Mlig455_046932 {REF} {Length: 920} {RNA1310_30968} {RNA815_45889}
8. MligTC455_54076 715 14.9 Mlig455_015419

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.789

 CUBN 1.722 - - - 0.969 0.753 - Mlig455_015419 {REF} {Length: 1794} {Pfam: CUB domain [PF00431.22, score=65.2]} {Human: ENSG00000107611, CUBN, cubilin, [Score=63.2, Expect=4e-10]; ENSG00000095587, TLL2, tolloid like 2, [Score=61.6, Expect=1e-09]; ENSG00000187908, DMBT1, deleted in malignant brain tumors 1, [Score=60.8, Expect=2e-09]; ENSG00000038295, TLL1, tolloid like 1, [Score=60.1, Expect=4e-09]} {Mouse: ENSMUSG00000026726, Cubn, cubilin (intrinsic factor-cobalamin receptor), [Score=72.0, Expect=4e-13]} {Dmel: FBgn0004885, tok, tolkin, [Score=58.9, Expect=4e-09]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [Score=64.7, Expect=4e-11]} {RNA1509_9300} {RNA1310_18452, RNA1509_9300} {RNA1509_9300, RNA815_8451}
9. MligTC455_19718 519 10.8 Mlig455_048439

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.528

Region-enriched R2: 2.401/0.00718

 ANKUB1 1.715 - - - 0.765 0.950 - Mlig455_048439 {REF} {Length: 3293} {Pfam: Ubiquitin family [PF00240.25, score=40.5]} {Human: ENSG00000206199, ANKUB1, ankyrin repeat and ubiquitin domain containing 1, [RH, Score=268, Expect=1e-81]} {Mouse: ENSMUSG00000074591, Ankub1, ankrin repeat and ubiquitin domain containing 1, [RH, Score=259, Expect=9e-79]} {Smed: dd_Smed_v6_9027_0_1, dd_Smed_v6_9027_0_1, [RH, Score=509, Expect=3e-174]} {RNA1509_10661, RNA1509_38601} {RNA1310_11316.2, RNA1509_10661, RNA1509_38601} {RNA1509_10661, RNA1509_38601, RNA815_657.1}
10. MligTC455_19666 354 7.37 Mlig455_045379

Neo: -

Age: -

 CFL1 1.705 - - 0.961 - 0.744 - Mlig455_045379 {REF} {Length: 1322} {TRANSSPLICED} {Pfam: Cofilin/tropomyosin-type actin-binding protein [PF00241.22, score=102.2]} {Human: ENSG00000172757, CFL1, cofilin 1, [Score=72.4, Expect=3e-16]; ENSG00000165410, CFL2, cofilin 2, [Score=70.5, Expect=2e-15]} {Mouse: ENSMUSG00000056201, Cfl1, cofilin 1, non-muscle, [Score=74.3, Expect=4e-17]} {Dmel: FBgn0030951, CG6873, [Score=63.2, Expect=3e-13]} {Celegans: WBGene00006794, unc-60, Actin-depolymerizing factor 2, isoform c, [Score=75.5, Expect=6e-18]} {Smed: dd_Smed_v6_260_0_1, dd_Smed_v6_260_0_1, [RH, Score=102, Expect=7e-29]} {RNA1509_37953, RNA1509_43405} {RNA1310_49748, RNA1509_37953, RNA1509_43405} {RNA1509_37953, RNA1509_43405, RNA815_9119.1}
11. MligTC455_40423 752 15.66 Mlig455_029299, Mlig455_058869

Neo: -

Age: Down-Up-Down

 CALM1 1.702 - - 0.749 - 0.953 -

Mlig455_029299 {REF} {Length: 1144} {Pfam: EF-hand domain pair [PF13833.8, score=47.6]; EF-hand domain pair [PF13499.8, score=39.7]; EF hand [PF00036.34, score=31.4]; EF-hand domain [PF13405.8, score=29.4]; EF-hand domain [PF14658.8, score=24.4]} {Human: ENSG00000198668, CALM1, calmodulin 1, [Score=100, Expect=1e-26]; ENSG00000143933, CALM2, calmodulin 2, [Score=100, Expect=1e-26]; ENSG00000160014, CALM3, calmodulin 3, [Score=100, Expect=1e-26]; ENSG00000178363, CALML3, calmodulin like 3, [Score=95.1, Expect=1e-24]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=100, Expect=8e-27]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=100, Expect=8e-27]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=100, Expect=8e-27]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=98.2, Expect=4e-26]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=98.2, Expect=4e-26]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=98.2, Expect=3e-26]} {RNA1509_16604} {RNA1310_33121} {RNA815_17390}

Mlig455_058869 {REF} {Length: 1325} {Pfam: EF-hand domain pair [PF13833.8, score=47.6]; EF-hand domain pair [PF13499.8, score=39.7]; EF hand [PF00036.34, score=31.4]; EF-hand domain [PF13405.8, score=29.4]; EF-hand domain [PF14658.8, score=24.4]} {Human: ENSG00000198668, CALM1, calmodulin 1, [Score=100, Expect=1e-26]; ENSG00000143933, CALM2, calmodulin 2, [Score=100, Expect=1e-26]; ENSG00000160014, CALM3, calmodulin 3, [Score=100, Expect=1e-26]; ENSG00000178363, CALML3, calmodulin like 3, [Score=95.1, Expect=1e-24]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=100, Expect=8e-27]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=100, Expect=8e-27]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=100, Expect=8e-27]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=98.2, Expect=4e-26]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=98.2, Expect=4e-26]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=98.2, Expect=3e-26]} {RNA1509_16604} {RNA1310_33121, RNA1509_16604} {RNA1509_16604, RNA815_17390}
12. MligTC455_30188 316 6.58 Mlig455_006262

Neo: -

Age: -

 GFAP 1.696 - - 0.962 - 0.734 - Mlig455_006262 {REF} {Length: 6771} {Pfam: Intermediate filament protein [PF00038.23, score=47.2]; Apolipoprotein A1/A4/E domain [PF01442.20, score=21.3]} {Human: ENSG00000131095, GFAP, glial fibrillary acidic protein, [Score=58.2, Expect=2e-10]} {Mouse: ENSMUSG00000020932, Gfap, glial fibrillary acidic protein, [Score=57.4, Expect=1e-09]; ENSMUSG00000026208, Des, desmin, [Score=56.2, Expect=3e-09]} {Dmel: FBgn0002525, Lam, Lamin, [Score=54.7, Expect=7e-09]} {Celegans: WBGene00002050, ifa-1, Intermediate filament protein ifa-1, [Score=77.8, Expect=5e-17]} {Smed: dd_Smed_v6_3871_0_1, dd_Smed_v6_3871_0_1, [Score=100, Expect=8e-25]} {RNA1509_50182} {RNA1310_9005} {RNA815_20094}
13. MligTC455_41464 507 10.57 Mlig455_053551

Neo: -

Age: -

 EIF2B1 1.675 - - 0.966 - 0.709 - Mlig455_053551 {REF} {Length: 6223} {TRANSSPLICED} {Pfam: Initiation factor 2 subunit family [PF01008.19, score=185.1]} {Human: ENSG00000111361, EIF2B1, eukaryotic translation initiation factor 2B subunit alpha, [Score=202, Expect=5e-58]} {Mouse: ENSMUSG00000029388, Eif2b1, eukaryotic translation initiation factor 2B, subunit 1 (alpha), [Score=208, Expect=2e-60]} {Dmel: FBgn0039726, eIF2Balpha, eukaryotic translation initiation factor 2B subunit alpha, [Score=216, Expect=1e-63]} {Celegans: WBGene00014221, eif-2Balpha, Probable translation initiation factor eIF-2B subunit alpha, [Score=192, Expect=5e-55]} {Smed: dd_Smed_v6_4682_0_1, dd_Smed_v6_4682_0_1, [Score=130, Expect=3e-33]} {RNA1509_30510, RNA1509_37474} {RNA1310_6473, RNA1509_30510} {RNA1509_30510, RNA815_14077}
14. MligTC455_41757 2210 46.04 Mlig455_067601

Neo: -

Age: Down-Down-Up

 0.97 - - - 0.970 - - Mlig455_067601 {REF} {Length: 2908} {Pfam: Thymosin beta-4 family [PF01290.22, score=118.1]} {Dmel: FBgn0026084, cib, ciboulot, [RH, Score=58.5, Expect=6e-11]} {Celegans: WBGene00006649, tth-1, Thymosin beta, [Score=45.8, Expect=3e-06]} {Smed: dd_Smed_v6_17_0_1, dd_Smed_v6_17_0_1, [Score=73.9, Expect=5e-17]} {RNA1509_2234, RNA1509_44322, RNA1509_48105, RNA1509_57771} {RNA1310_19846.1, RNA1509_2234, RNA1509_44322, RNA1509_48105, RNA1509_57771} {RNA1509_2234, RNA1509_44322, RNA1509_48105, RNA1509_57771, RNA815_7395.2}
15. MligTC455_29776 242 5.05 Mlig455_039026

Neo: -

Age: -

 0.964 - - - - 0.964 - Mlig455_039026 {REF} {Length: 3171} {RNA1509_52854, RNA1509_6748} {RNA1310_18154, RNA1509_52854} {RNA1509_52854, RNA815_24422.1}
16. MligTC455_46125 321 6.69 Mlig455_058178, Mlig455_058209

Neo: -

Age: logFC(26M/2M)=0.817

Regeneration-upregulated BL: 2.786

Regeneration-enriched BL: 2.786

 0.963 - - - - 0.963 -

Mlig455_058178 {REF} {Length: 2359} {Pfam: PLAC8 family [PF04749.19, score=68.6]} {Smed: dd_Smed_v6_477_0_1, dd_Smed_v6_477_0_1, [Score=121, Expect=4e-37]} {RNA1509_56540} {RNA1310_30391} {RNA815_19375}

Mlig455_058209 {REF} {Length: 2299} {Pfam: PLAC8 family [PF04749.19, score=68.6]} {Smed: dd_Smed_v6_477_0_1, dd_Smed_v6_477_0_1, [Score=121, Expect=4e-37]} {RNA1509_56540} {RNA1310_30391, RNA1509_56540} {RNA1509_56540, RNA815_19375}
17. MligTC455_46583 1098 22.87 Mlig455_067509

Neo: -

Age: logFC(26M/2M)=-0.318

Region-enriched R8: 2.830/0.00000
Region-enriched R7: 1.613/0.00085

Regeneration-depleted TP: -3.677
Regeneration-depleted BL: -2.763
Regeneration-depleted R4: -2.132
Regeneration-depleted R2: -1.934

 0.962 - - - - 0.962 - Mlig455_067509 {REF} {Length: 1536} {Pfam: Low-density lipoprotein receptor domain class A [PF00057.20, score=25.3]} {Dmel: FBgn0051221, CG31221, [Score=62.8, Expect=5e-12]} {Celegans: WBGene00010290, F58H1.7, [RH, Score=66.6, Expect=1e-13]} {Smed: dd_Smed_v6_2598_0_1, dd_Smed_v6_2598_0_1, [RH, Score=173, Expect=3e-55]} {RNA1509_59060} {RNA1310_28256} {RNA815_15141.1}
18. MligTC455_18995 286 5.95 Mlig455_032923

Neo: -

Age: -

Region-specific R2: 4.016

Region-enriched R2: 3.125/0.00121

 0.961 - - - - 0.961 - Mlig455_032923 {REF} {Length: 1576} {Pfam: Transposase DDE domain [PF01609.23, score=18.9]} {RNA1509_39626} {RNA1310_29809, RNA1509_39626} {RNA1509_39626, RNA815_13636}
19. MligTC455_40125 953 19.86 Mlig455_005600, Mlig455_014458

Neo: -

Age: Up-Down-Down

 KIF13B, KIF1B 0.961 - - - - 0.961 -

Mlig455_005600 {REF} {Length: 4684} {Pfam: Kinesin protein 1B [PF12423.10, score=42.5]} {Human: ENSG00000197892, KIF13B, kinesin family member 13B, [Score=61.6, Expect=2e-09]} {Mouse: ENSMUSG00000087236, Kif28, kinesin family member 28, [Score=98.2, Expect=4e-21]} {Dmel: FBgn0019968, Khc-73, Kinesin heavy chain 73, [Score=57.0, Expect=3e-08]} {Celegans: WBGene00002218, klp-6, Kinesin-like protein, [Score=177, Expect=5e-48]} {Smed: dd_Smed_v6_20223_0_1, dd_Smed_v6_20223_0_1, [Score=118, Expect=3e-28]} {RNA1509_6760} {RNA1310_2628} {RNA815_4402}

Mlig455_014458 {REF} {Length: 3819} {Pfam: Kinesin motor domain [PF00225.25, score=336.4]; Microtubule binding [PF16796.7, score=68.9]; Kinesin protein 1B [PF12423.10, score=40.0]; Kinesin-associated [PF16183.7, score=27.3]} {Human: ENSG00000054523, KIF1B, kinesin family member 1B, [Score=404, Expect=2e-123]; ENSG00000137177, KIF13A, kinesin family member 13A, [Score=404, Expect=9e-120]; ENSG00000130294, KIF1A, kinesin family member 1A, [Score=404, Expect=2e-120]; ENSG00000197892, KIF13B, kinesin family member 13B, [Score=399, Expect=2e-125]; ENSG00000129250, KIF1C, kinesin family member 1C, [Score=398, Expect=2e-121]} {Mouse: ENSMUSG00000087236, Kif28, kinesin family member 28, [Score=568, Expect=0.0]} {Dmel: FBgn0019968, Khc-73, Kinesin heavy chain 73, [Score=415, Expect=5e-124]} {Celegans: WBGene00002218, klp-6, Kinesin-like protein, [RH, Score=818, Expect=0.0]} {Smed: dd_Smed_v6_12573_0_1, dd_Smed_v6_12573_0_1, [Score=617, Expect=0.0]} {RNA1509_6760} {RNA1310_1667.1} {RNA815_1144}
20. MligTC455_07847 1096 22.84 Mlig455_012556, Mlig455_012557, Mlig455_012561

Neo: -

Age: Down-Up-Down

 FRK, LCK, YES1 0.96 - - - 0.960 - -

Mlig455_012556 {REF} {Length: 708} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=259.4]; Protein kinase domain [PF00069.27, score=135.8]; Haspin like kinase domain [PF12330.10, score=20.1]; Kinase-like [PF14531.8, score=18.9]} {Human: ENSG00000111816, FRK, fyn related Src family tyrosine kinase, [Score=229, Expect=3e-72]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=218, Expect=8e-68]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=218, Expect=1e-67]} {Mouse: ENSMUSG00000019779, Frk, fyn-related kinase, [Score=223, Expect=9e-70]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=218, Expect=2e-68]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=217, Expect=9e-68]; ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=216, Expect=8e-67]; ENSMUSG00000027646, Src, Rous sarcoma oncogene, [Score=215, Expect=1e-66]; ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=214, Expect=1e-66]; ENSMUSG00000003283, Hck, hemopoietic cell kinase, [Score=213, Expect=3e-66]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=238, Expect=6e-76]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=237, Expect=7e-76]} {Smed: dd_Smed_v6_3363_0_2, dd_Smed_v6_3363_0_2, [Score=257, Expect=9e-84]} {RNA1509_39741} {RNA1310_36414} {RNA815_3276.1}

Mlig455_012557 {REF} {Length: 2434} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=283.3]; Protein kinase domain [PF00069.27, score=161.5]; SH3 domain [PF00018.30, score=49.1]; SH2 domain [PF00017.26, score=47.6]; Variant SH3 domain [PF07653.19, score=34.0]; Variant SH3 domain [PF14604.8, score=29.9]; ABC1 atypical kinase-like domain [PF03109.18, score=22.5]; Haspin like kinase domain [PF12330.10, score=19.3]} {Human: ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=371, Expect=1e-122]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=366, Expect=1e-120]; ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=359, Expect=9e-118]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=358, Expect=6e-118]; ENSG00000176105, YES1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=358, Expect=4e-117]; ENSG00000197122, SRC, SRC proto-oncogene, non-receptor tyrosine kinase, [Score=354, Expect=7e-116]} {Mouse: ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=374, Expect=9e-124]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=362, Expect=2e-119]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=360, Expect=5e-118]; ENSMUSG00000003283, Hck, hemopoietic cell kinase, [Score=358, Expect=6e-118]; ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=357, Expect=3e-117]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=376, Expect=1e-124]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=374, Expect=8e-125]} {Smed: dd_Smed_v6_3363_0_1, dd_Smed_v6_3363_0_1, [Score=456, Expect=8e-157]} {RNA1509_27796, RNA1509_39741, RNA1509_58341} {RNA1310_9777, RNA1509_39741, RNA1509_58341} {RNA1509_39741, RNA1509_58341, RNA815_3276.1}

Mlig455_012561 {REF} {Length: 2422} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=153.7]; Protein kinase domain [PF00069.27, score=86.2]; Haspin like kinase domain [PF12330.10, score=20.3]; Kinase-like [PF14531.8, score=19.7]} {Human: ENSG00000176105, YES1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=139, Expect=1e-39]; ENSG00000197122, SRC, SRC proto-oncogene, non-receptor tyrosine kinase, [Score=137, Expect=6e-39]; ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=137, Expect=9e-39]; ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=136, Expect=1e-38]; ENSG00000000938, FGR, FGR proto-oncogene, Src family tyrosine kinase, [Score=136, Expect=1e-38]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=134, Expect=6e-38]} {Mouse: ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=139, Expect=1e-39]; ENSMUSG00000028874, Fgr, FGR proto-oncogene, Src family tyrosine kinase, [Score=139, Expect=1e-39]; ENSMUSG00000027646, Src, Rous sarcoma oncogene, [Score=137, Expect=5e-39]; ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=136, Expect=8e-39]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=136, Expect=9e-39]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=134, Expect=4e-38]; ENSMUSG00000027579, Srms, src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites, [Score=134, Expect=6e-38]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=140, Expect=2e-39]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=135, Expect=3e-41]} {Smed: dd_Smed_v6_3147_0_1, dd_Smed_v6_3147_0_1, [Score=143, Expect=1e-41]} {RNA1509_27796} {RNA1310_9777} {RNA815_3276.1}
21. MligTC455_37276 449 9.36 Mlig455_053415

Neo: -

Age: -

 CEP104 0.959 - - - 0.959 - - Mlig455_053415 {REF} {Length: 5760} {TRANSSPLICED} {Pfam: UvrB/uvrC motif [PF02151.21, score=28.0]} {Human: ENSG00000116198, CEP104, centrosomal protein 104, [RH, Score=640, Expect=0.0]} {Mouse: ENSMUSG00000039523, Cep104, centrosomal protein 104, [Score=629, Expect=0.0]} {Dmel: FBgn0032800, CG10137, [RH, Score=207, Expect=3e-55]} {Celegans: WBGene00011523, T06D8.2, [RH, Score=83.6, Expect=3e-16]} {Smed: dd_Smed_v6_10228_0_1, dd_Smed_v6_10228_0_1, [RH, Score=686, Expect=0.0]} {RNA1509_29154, RNA1509_3191, RNA1509_50427} {RNA1310_3596.2, RNA1509_29154, RNA1509_3191, RNA1509_50427} {RNA1509_29154, RNA1509_3191, RNA1509_50427, RNA815_945}
22. MligTC455_24455 131 2.72 Mlig455_006310

Neo: -

Age: -

 0.956 - - - - 0.956 - Mlig455_006310 {REF} {Length: 2448} {RNA1509_7020} {RNA1310_76552} {RNA815_41542}
23. MligTC455_28430 161 3.35 Mlig455_058777, Mlig455_066475

Neo: -

Age: -

 0.956 - - - - 0.956 -

Mlig455_058777 {REF} {Length: 1822} {RNA1509_18349} {RNA1310_37185} {RNA815_17990}

Mlig455_066475 {REF} {Length: 5204} {tRNA: Val(CAC),pseudo, score=36.5} {RNA1509_21400} {RNA1310_576.1} {RNA815_2733.1}
24. MligTC455_23310 304 6.34 Mlig455_061447

Neo: -

Age: Down-Up-Down

 0.955 - - 0.955 - - - Mlig455_061447 {REF} {Length: 953} {RNA1509_48616} {RNA1310_6959} {RNA815_10949}
25. MligTC455_29169 108 2.25 Mlig455_002330

Neo: -

Age: Up-Down-Down

 DNAH5 0.955 - - - - 0.955 - Mlig455_002330 {REF} {Length: 14879} {Pfam: Dynein heavy chain, N-terminal region 1 [PF08385.14, score=576.9]; Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=466.5]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=429.5]; Dynein heavy chain C-terminal domain [PF18199.3, score=313.2]; P-loop containing dynein motor region D4 [PF12780.9, score=303.1]; ATP-binding dynein motor region [PF12781.9, score=290.8]; P-loop containing dynein motor region [PF12775.9, score=229.8]; Dynein heavy chain AAA lid domain [PF18198.3, score=179.2]; Microtubule-binding stalk of dynein motor [PF12777.9, score=144.8]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=121.4]; AAA domain (dynein-related subfamily) [PF07728.16, score=75.6]; Dynein heavy chain AAA lid domain [PF17852.3, score=70.5]; AAA+ lid domain [PF17857.3, score=60.9]; AAA ATPase domain [PF13191.8, score=21.9]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=21.3]; P-loop containing region of AAA domain [PF13555.8, score=20.3]} {Human: ENSG00000039139, DNAH5, dynein axonemal heavy chain 5, [RH, Score=6256, Expect=0.0]} {Mouse: ENSMUSG00000022262, Dnah5, dynein, axonemal, heavy chain 5, [RH, Score=6232, Expect=0.0]} {Dmel: FBgn0037726, CG9492, [RH, Score=5094, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=1294, Expect=0.0]} {Smed: dd_Smed_v6_4569_0_1, dd_Smed_v6_4569_0_1, [RH, Score=6936, Expect=0.0]} {RNA1509_39171, RNA1509_51275} {RNA1310_408, RNA1509_39171} {RNA1509_39171, RNA815_44.1}
26. MligTC455_39312 101 2.11 Mlig455_002158

Neo: -

Age: -

 CFAP99 0.955 - - - - 0.955 - Mlig455_002158 {REF} {Length: 4740} {Pfam: Thyroglobulin type-1 repeat [PF00086.20, score=82.5]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=43.8]; Kazal-type serine protease inhibitor domain [PF07648.17, score=35.9]; Kazal-type serine protease inhibitor domain [PF00050.23, score=35.3]; EF-hand domain pair [PF13499.8, score=29.0]; EF-hand domain [PF13405.8, score=27.5]; EF hand [PF00036.34, score=23.2]; EF hand [PF13202.8, score=19.1]} {Human: ENSG00000206113, CFAP99, cilia and flagella associated protein 99, [RH, Score=302, Expect=4e-88]} {Mouse: ENSMUSG00000109572, Cfap99, cilia and flagella associated protein 99, [RH, Score=308, Expect=3e-90]} {Dmel: FBgn0262169, magu, [RH, Score=144, Expect=4e-35]} {Smed: dd_Smed_v6_8538_0_1, dd_Smed_v6_8538_0_1, [RH, Score=342, Expect=5e-103]} {RNA1509_16659} {RNA1310_6756} {RNA815_2531}
27. MligTC455_52120 179 3.73 Mlig455_024423, Mlig455_024577

Neo: -

Age: Down-Up-Down

Region-enriched R2: 4.068/0.01755

 POU4F3 0.955 - - - - 0.955 -

Mlig455_024423 {REF} {Length: 1288} {TRANSSPLICED} {Pfam: Pou domain - N-terminal to homeobox domain [PF00157.19, score=104.8]; Homeodomain [PF00046.31, score=60.9]} {Human: ENSG00000091010, POU4F3, POU class 4 homeobox 3, [Score=212, Expect=1e-65]; ENSG00000152192, POU4F1, POU class 4 homeobox 1, [Score=211, Expect=2e-64]} {Mouse: ENSMUSG00000024497, Pou4f3, POU domain, class 4, transcription factor 3, [Score=212, Expect=7e-66]; ENSMUSG00000048349, Pou4f1, POU domain, class 4, transcription factor 1, [Score=211, Expect=2e-64]} {Dmel: FBgn0000028, acj6, abnormal chemosensory jump 6, [Score=209, Expect=2e-64]} {Celegans: WBGene00006818, unc-86, Transcription factor unc-86, [Score=188, Expect=4e-57]} {Smed: dd_Smed_v6_30562_0_1, dd_Smed_v6_30562_0_1, [Score=208, Expect=2e-64]} {RNA1509_57422} {RNA1310_23131} {RNA815_34447}

Mlig455_024577 {REF} {Length: 1325} {TRANSSPLICED} {Pfam: Pou domain - N-terminal to homeobox domain [PF00157.19, score=104.8]; Homeodomain [PF00046.31, score=60.9]} {Human: ENSG00000091010, POU4F3, POU class 4 homeobox 3, [Score=212, Expect=1e-65]; ENSG00000152192, POU4F1, POU class 4 homeobox 1, [Score=211, Expect=2e-64]} {Mouse: ENSMUSG00000024497, Pou4f3, POU domain, class 4, transcription factor 3, [Score=212, Expect=7e-66]; ENSMUSG00000048349, Pou4f1, POU domain, class 4, transcription factor 1, [Score=211, Expect=2e-64]} {Dmel: FBgn0000028, acj6, abnormal chemosensory jump 6, [Score=209, Expect=2e-64]} {Celegans: WBGene00006818, unc-86, Transcription factor unc-86, [Score=188, Expect=4e-57]} {Smed: dd_Smed_v6_30562_0_1, dd_Smed_v6_30562_0_1, [Score=208, Expect=2e-64]} {RNA1509_57422} {RNA1310_23131} {RNA815_34447}
28. MligTC455_24943 1500 31.26 Mlig455_011375

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.341

Region-enriched R2: 1.044/0.02295

 0.954 - - - - 0.954 - Mlig455_011375 {REF} {Length: 3494} {TRANSSPLICED} {Pfam: Reeler domain [PF02014.18, score=52.6]; Eukaryotic cytochrome b561 [PF03188.18, score=36.8]; DOMON domain [PF03351.19, score=30.3]} {Mouse: ENSMUSG00000033386, Frrs1, ferric-chelate reductase 1, [Score=110, Expect=8e-25]} {Celegans: WBGene00007339, C05D12.1, [Score=57.4, Expect=2e-08]} {Smed: dd_Smed_v6_13311_0_1, dd_Smed_v6_13311_0_1, [RH, Score=165, Expect=2e-43]} {RNA1509_50878} {RNA1310_5459.1} {RNA815_10113}
29. MligTC455_41669 480 10.01 Mlig455_040778, Mlig455_064613

Neo: -

Age: Down-Down-Up

 0.953 - - - - 0.953 -

Mlig455_040778 {REF} {Length: 2233} {RNA1310_31511} {RNA815_21534}

Mlig455_064613 {REF} {Length: 1332} {RNA1310_32935} {RNA815_21534}
30. MligTC455_44883 146 3.04 Mlig455_045714

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.068/0.02935

 OGFR 0.953 - - - - 0.953 - Mlig455_045714 {REF} {Length: 5397} {Pfam: PT repeat [PF04886.14, score=183.6]} {Human: ENSG00000060491, OGFR, opioid growth factor receptor, [Score=75.1, Expect=7e-13]} {Mouse: ENSMUSG00000053198, Prx, periaxin, [RH, Score=56.2, Expect=4e-07]} {Dmel: FBgn0029807, CG3108, [Score=96.3, Expect=2e-19]} {Smed: dd_Smed_v6_5981_0_1, dd_Smed_v6_5981_0_1, [Score=50.8, Expect=2e-06]} {RNA1509_58926} {RNA1310_37131} {RNA815_16145}
31. MligTC455_13293 364 7.59 Mlig455_012562

Neo: -

Age: Down-Up-Down

 FYN 0.95 - - - 0.950 - - Mlig455_012562 {REF} {Length: 2323} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=272.2]; Protein kinase domain [PF00069.27, score=145.0]; SH2 domain [PF00017.26, score=47.5]; SH3 domain [PF00018.30, score=43.5]; Variant SH3 domain [PF07653.19, score=29.7]; Variant SH3 domain [PF14604.8, score=29.4]; Haspin like kinase domain [PF12330.10, score=21.4]; ABC1 atypical kinase-like domain [PF03109.18, score=18.6]} {Human: ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=366, Expect=8e-121]; ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=364, Expect=1e-120]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=357, Expect=5e-118]; ENSG00000176105, YES1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=357, Expect=2e-117]; ENSG00000197122, SRC, SRC proto-oncogene, non-receptor tyrosine kinase, [Score=352, Expect=2e-115]} {Mouse: ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=369, Expect=3e-122]; ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=365, Expect=6e-121]; ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=357, Expect=2e-117]; ENSMUSG00000027646, Src, Rous sarcoma oncogene, [Score=352, Expect=1e-115]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=361, Expect=1e-119]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=379, Expect=4e-127]} {Smed: dd_Smed_v6_3363_0_2, dd_Smed_v6_3363_0_2, [Score=431, Expect=1e-147]} {RNA1509_28839} {RNA1310_8178.1} {RNA815_4079.1}

Refine r cutoff to:    Show

Berezikov Lab - 2020-2021 © ERIBA