Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_07847 | 1096 | 22.84 | Mlig455_012556, Mlig455_012557, Mlig455_012561 | Neo: - Age: Down-Up-Down |
FRK, LCK, YES1 | Mlig455_012556 {REF} {Length: 708} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=259.4]; Protein kinase domain [PF00069.27, score=135.8]; Haspin like kinase domain [PF12330.10, score=20.1]; Kinase-like [PF14531.8, score=18.9]} {Human: ENSG00000111816, FRK, fyn related Src family tyrosine kinase, [Score=229, Expect=3e-72]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=218, Expect=8e-68]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=218, Expect=1e-67]} {Mouse: ENSMUSG00000019779, Frk, fyn-related kinase, [Score=223, Expect=9e-70]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=218, Expect=2e-68]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=217, Expect=9e-68]; ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=216, Expect=8e-67]; ENSMUSG00000027646, Src, Rous sarcoma oncogene, [Score=215, Expect=1e-66]; ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=214, Expect=1e-66]; ENSMUSG00000003283, Hck, hemopoietic cell kinase, [Score=213, Expect=3e-66]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=238, Expect=6e-76]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=237, Expect=7e-76]} {Smed: dd_Smed_v6_3363_0_2, dd_Smed_v6_3363_0_2, [Score=257, Expect=9e-84]} {RNA1509_39741} {RNA1310_36414} {RNA815_3276.1} Mlig455_012557 {REF} {Length: 2434} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=283.3]; Protein kinase domain [PF00069.27, score=161.5]; SH3 domain [PF00018.30, score=49.1]; SH2 domain [PF00017.26, score=47.6]; Variant SH3 domain [PF07653.19, score=34.0]; Variant SH3 domain [PF14604.8, score=29.9]; ABC1 atypical kinase-like domain [PF03109.18, score=22.5]; Haspin like kinase domain [PF12330.10, score=19.3]} {Human: ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=371, Expect=1e-122]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=366, Expect=1e-120]; ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=359, Expect=9e-118]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=358, Expect=6e-118]; ENSG00000176105, YES1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=358, Expect=4e-117]; ENSG00000197122, SRC, SRC proto-oncogene, non-receptor tyrosine kinase, [Score=354, Expect=7e-116]} {Mouse: ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=374, Expect=9e-124]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=362, Expect=2e-119]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=360, Expect=5e-118]; ENSMUSG00000003283, Hck, hemopoietic cell kinase, [Score=358, Expect=6e-118]; ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=357, Expect=3e-117]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=376, Expect=1e-124]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=374, Expect=8e-125]} {Smed: dd_Smed_v6_3363_0_1, dd_Smed_v6_3363_0_1, [Score=456, Expect=8e-157]} {RNA1509_27796, RNA1509_39741, RNA1509_58341} {RNA1310_9777, RNA1509_39741, RNA1509_58341} {RNA1509_39741, RNA1509_58341, RNA815_3276.1} Mlig455_012561 {REF} {Length: 2422} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=153.7]; Protein kinase domain [PF00069.27, score=86.2]; Haspin like kinase domain [PF12330.10, score=20.3]; Kinase-like [PF14531.8, score=19.7]} {Human: ENSG00000176105, YES1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=139, Expect=1e-39]; ENSG00000197122, SRC, SRC proto-oncogene, non-receptor tyrosine kinase, [Score=137, Expect=6e-39]; ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=137, Expect=9e-39]; ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=136, Expect=1e-38]; ENSG00000000938, FGR, FGR proto-oncogene, Src family tyrosine kinase, [Score=136, Expect=1e-38]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=134, Expect=6e-38]} {Mouse: ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=139, Expect=1e-39]; ENSMUSG00000028874, Fgr, FGR proto-oncogene, Src family tyrosine kinase, [Score=139, Expect=1e-39]; ENSMUSG00000027646, Src, Rous sarcoma oncogene, [Score=137, Expect=5e-39]; ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=136, Expect=8e-39]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=136, Expect=9e-39]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=134, Expect=4e-38]; ENSMUSG00000027579, Srms, src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites, [Score=134, Expect=6e-38]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=140, Expect=2e-39]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=135, Expect=3e-41]} {Smed: dd_Smed_v6_3147_0_1, dd_Smed_v6_3147_0_1, [Score=143, Expect=1e-41]} {RNA1509_27796} {RNA1310_9777} {RNA815_3276.1} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -1.398 | 4.813 | 0.21514 | 0.85582 | |
RegionR2 | 0.712 | 4.813 | 0.04247 | 0.24155 | |
RegionR3 | 0.505 | 4.813 | 0.08082 | 0.50310 | |
RegionR4 | 0.359 | 4.813 | 0.29695 | 0.60897 | |
RegionR5 | -0.796 | 4.813 | 0.02136 | 0.10166 | |
RegionR6 | -0.108 | 4.813 | 0.74602 | 1.00000 | |
RegionR7 | 0.4 | 4.813 | 0.30674 | 0.94111 | |
RegionR8 | 0.325 | 4.813 | 0.52423 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -6.787 | 4.813 | 0.13751 | 0.87386 | |
RegenerationR2 | -0.194 | 4.813 | 0.46226 | 0.85353 | |
RegenerationR3 | -0.365 | 4.813 | 0.22958 | 0.66434 | |
RegenerationR4 | -0.342 | 4.813 | 0.26807 | 0.71460 | |
RegenerationR5 | 0.422 | 4.813 | 0.17347 | 0.60254 | |
RegenerationR6 | 0.042 | 4.813 | 0.89688 | 1.00000 | |
RegenerationBL | -0.34 | 4.813 | 0.38810 | 0.75643 | |
RegenerationTP | 0.227 | 4.813 | 0.56974 | 0.94468 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_07847 | 1096 | 22.84 | Mlig455_012556, Mlig455_012557, Mlig455_012561 | Neo: - Age: Down-Up-Down |
FRK, LCK, YES1 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_012556 {REF} {Length: 708} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=259.4]; Protein kinase domain [PF00069.27, score=135.8]; Haspin like kinase domain [PF12330.10, score=20.1]; Kinase-like [PF14531.8, score=18.9]} {Human: ENSG00000111816, FRK, fyn related Src family tyrosine kinase, [Score=229, Expect=3e-72]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=218, Expect=8e-68]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=218, Expect=1e-67]} {Mouse: ENSMUSG00000019779, Frk, fyn-related kinase, [Score=223, Expect=9e-70]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=218, Expect=2e-68]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=217, Expect=9e-68]; ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=216, Expect=8e-67]; ENSMUSG00000027646, Src, Rous sarcoma oncogene, [Score=215, Expect=1e-66]; ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=214, Expect=1e-66]; ENSMUSG00000003283, Hck, hemopoietic cell kinase, [Score=213, Expect=3e-66]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=238, Expect=6e-76]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=237, Expect=7e-76]} {Smed: dd_Smed_v6_3363_0_2, dd_Smed_v6_3363_0_2, [Score=257, Expect=9e-84]} {RNA1509_39741} {RNA1310_36414} {RNA815_3276.1} Mlig455_012557 {REF} {Length: 2434} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=283.3]; Protein kinase domain [PF00069.27, score=161.5]; SH3 domain [PF00018.30, score=49.1]; SH2 domain [PF00017.26, score=47.6]; Variant SH3 domain [PF07653.19, score=34.0]; Variant SH3 domain [PF14604.8, score=29.9]; ABC1 atypical kinase-like domain [PF03109.18, score=22.5]; Haspin like kinase domain [PF12330.10, score=19.3]} {Human: ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=371, Expect=1e-122]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=366, Expect=1e-120]; ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=359, Expect=9e-118]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=358, Expect=6e-118]; ENSG00000176105, YES1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=358, Expect=4e-117]; ENSG00000197122, SRC, SRC proto-oncogene, non-receptor tyrosine kinase, [Score=354, Expect=7e-116]} {Mouse: ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=374, Expect=9e-124]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=362, Expect=2e-119]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=360, Expect=5e-118]; ENSMUSG00000003283, Hck, hemopoietic cell kinase, [Score=358, Expect=6e-118]; ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=357, Expect=3e-117]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=376, Expect=1e-124]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=374, Expect=8e-125]} {Smed: dd_Smed_v6_3363_0_1, dd_Smed_v6_3363_0_1, [Score=456, Expect=8e-157]} {RNA1509_27796, RNA1509_39741, RNA1509_58341} {RNA1310_9777, RNA1509_39741, RNA1509_58341} {RNA1509_39741, RNA1509_58341, RNA815_3276.1} Mlig455_012561 {REF} {Length: 2422} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=153.7]; Protein kinase domain [PF00069.27, score=86.2]; Haspin like kinase domain [PF12330.10, score=20.3]; Kinase-like [PF14531.8, score=19.7]} {Human: ENSG00000176105, YES1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=139, Expect=1e-39]; ENSG00000197122, SRC, SRC proto-oncogene, non-receptor tyrosine kinase, [Score=137, Expect=6e-39]; ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=137, Expect=9e-39]; ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=136, Expect=1e-38]; ENSG00000000938, FGR, FGR proto-oncogene, Src family tyrosine kinase, [Score=136, Expect=1e-38]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=134, Expect=6e-38]} {Mouse: ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=139, Expect=1e-39]; ENSMUSG00000028874, Fgr, FGR proto-oncogene, Src family tyrosine kinase, [Score=139, Expect=1e-39]; ENSMUSG00000027646, Src, Rous sarcoma oncogene, [Score=137, Expect=5e-39]; ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=136, Expect=8e-39]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=136, Expect=9e-39]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=134, Expect=4e-38]; ENSMUSG00000027579, Srms, src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites, [Score=134, Expect=6e-38]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=140, Expect=2e-39]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=135, Expect=3e-41]} {Smed: dd_Smed_v6_3147_0_1, dd_Smed_v6_3147_0_1, [Score=143, Expect=1e-41]} {RNA1509_27796} {RNA1310_9777} {RNA815_3276.1} |
2. | MligTC455_07848 | 718 | 14.95 | Mlig455_070235 | Neo: - Age: - |
LCK | 3.666 | - | 0.880 | - | 0.971 | 0.904 | 0.911 | Mlig455_070235 {REF} {Length: 2482} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=288.1]; Protein kinase domain [PF00069.27, score=161.5]; SH3 domain [PF00018.30, score=50.6]; SH2 domain [PF00017.26, score=46.4]; Variant SH3 domain [PF07653.19, score=34.2]; Variant SH3 domain [PF14604.8, score=29.7]; ABC1 atypical kinase-like domain [PF03109.18, score=25.0]; Haspin like kinase domain [PF12330.10, score=20.3]} {Human: ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=374, Expect=5e-124]; ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=371, Expect=3e-122]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=369, Expect=8e-122]; ENSG00000176105, YES1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=365, Expect=6e-120]; ENSG00000197122, SRC, SRC proto-oncogene, non-receptor tyrosine kinase, [Score=360, Expect=3e-118]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=360, Expect=9e-119]; ENSG00000136573, BLK, BLK proto-oncogene, Src family tyrosine kinase, [Score=357, Expect=2e-117]} {Mouse: ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=375, Expect=3e-124]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=371, Expect=2e-122]; ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=365, Expect=5e-120]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=363, Expect=6e-120]; ENSMUSG00000003283, Hck, hemopoietic cell kinase, [Score=362, Expect=2e-119]; ENSMUSG00000027646, Src, Rous sarcoma oncogene, [Score=360, Expect=5e-118]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=389, Expect=8e-130]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=385, Expect=5e-129]} {Smed: dd_Smed_v6_3363_0_1, dd_Smed_v6_3363_0_1, [Score=466, Expect=2e-160]} {RNA1509_21410, RNA1509_27796, RNA1509_54196} {RNA1310_9777, RNA1509_21410, RNA1509_27796, RNA1509_54196} {RNA1509_21410, RNA1509_27796, RNA1509_54196, RNA815_3276.1} |
3. | MligTC455_45207 | 1239 | 25.82 | Mlig455_032063 | Neo: - Age: Down-Down-Up |
2.54 | - | - | 0.855 | 0.963 | 0.722 | - | Mlig455_032063 {REF} {Length: 2507} {RNA1509_35528} {RNA1310_3497.1} {RNA815_14551} | |
4. | MligTC455_26574 | 1008 | 21 | Mlig455_036012 | Neo: - Age: - Region-enriched R2: 1.522/0.03494 |
MAP3K19 | 2.499 | - | - | 0.814 | 0.961 | - | 0.724 | Mlig455_036012 {REF} {Length: 2945} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=314.2]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=250.5]; Fungal protein kinase [PF17667.3, score=46.2]; Kinase-like [PF14531.8, score=44.9]; ABC1 atypical kinase-like domain [PF03109.18, score=30.3]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=136, Expect=1e-33]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=135, Expect=3e-33]} {Dmel: FBgn0024329, Mekk1, [Score=125, Expect=4e-29]} {Celegans: WBGene00006941, wnk-1, Serine/threonine-protein kinase WNK, [Score=110, Expect=9e-25]} {Smed: dd_Smed_v6_4849_0_2, dd_Smed_v6_4849_0_2, [Score=126, Expect=6e-30]} {RNA1509_1991, RNA1509_42299} {RNA1310_4947, RNA1509_1991, RNA1509_42299} {RNA1509_1991, RNA1509_42299, RNA815_3455} |
5. | MligTC455_42078 | 610 | 12.7 | Mlig455_026446 | Neo: - Age: logFC(26M/2M)=0.606 |
1.816 | - | 0.849 | - | - | 0.967 | - | Mlig455_026446 {REF} {Length: 464} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_31054} {RNA1310_56045} {RNA815_29646} | |
6. | MligTC455_18204 | 1518 | 31.63 | Mlig455_011842 | Neo: - Age: Down-Down-Up Region-enriched R2: 1.269/0.02855 |
CALM3 | 1.813 | - | 0.863 | - | - | 0.950 | - | Mlig455_011842 {REF} {Length: 692} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=50.8]; EF-hand domain [PF14658.8, score=37.7]; EF-hand domain pair [PF13833.8, score=37.3]; EF-hand domain [PF13405.8, score=26.0]; EF hand [PF00036.34, score=25.9]; Uncharacterised protein family (UPF0154) [PF03672.15, score=20.6]} {Human: ENSG00000160014, CALM3, calmodulin 3, [Score=134, Expect=2e-40]; ENSG00000198668, CALM1, calmodulin 1, [Score=134, Expect=2e-40]; ENSG00000143933, CALM2, calmodulin 2, [Score=134, Expect=2e-40]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=134, Expect=1e-40]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=134, Expect=1e-40]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=134, Expect=1e-40]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=133, Expect=1e-40]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=132, Expect=2e-40]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=132, Expect=2e-40]} {RNA1509_10890} {RNA1310_49762.1} {RNA815_25161.1} |
7. | MligTC455_13293 | 364 | 7.59 | Mlig455_012562 | Neo: - Age: Down-Up-Down |
FYN | 1.786 | - | - | - | 0.952 | - | 0.834 | Mlig455_012562 {REF} {Length: 2323} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=272.2]; Protein kinase domain [PF00069.27, score=145.0]; SH2 domain [PF00017.26, score=47.5]; SH3 domain [PF00018.30, score=43.5]; Variant SH3 domain [PF07653.19, score=29.7]; Variant SH3 domain [PF14604.8, score=29.4]; Haspin like kinase domain [PF12330.10, score=21.4]; ABC1 atypical kinase-like domain [PF03109.18, score=18.6]} {Human: ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=366, Expect=8e-121]; ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=364, Expect=1e-120]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=357, Expect=5e-118]; ENSG00000176105, YES1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=357, Expect=2e-117]; ENSG00000197122, SRC, SRC proto-oncogene, non-receptor tyrosine kinase, [Score=352, Expect=2e-115]} {Mouse: ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=369, Expect=3e-122]; ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=365, Expect=6e-121]; ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=357, Expect=2e-117]; ENSMUSG00000027646, Src, Rous sarcoma oncogene, [Score=352, Expect=1e-115]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=361, Expect=1e-119]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=379, Expect=4e-127]} {Smed: dd_Smed_v6_3363_0_2, dd_Smed_v6_3363_0_2, [Score=431, Expect=1e-147]} {RNA1509_28839} {RNA1310_8178.1} {RNA815_4079.1} |
8. | MligTC455_53045 | 1316 | 27.42 | Mlig455_026988 | Neo: - Age: Down-Down-Up Region-enriched R4: 1.692/0.00217 |
DYNLL1 | 1.786 | - | - | - | - | 0.953 | 0.833 | Mlig455_026988 {REF} {Length: 830} {Pfam: Dynein light chain type 1 [PF01221.20, score=67.9]; EF hand [PF00036.34, score=47.4]; EF-hand domain pair [PF13499.8, score=44.1]; EF-hand domain [PF13405.8, score=36.6]; EF hand [PF13202.8, score=35.1]; EF-hand domain pair [PF13833.8, score=29.2]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=18.7]} {Human: ENSG00000088986, DYNLL1, dynein light chain LC8-type 1, [Score=51.2, Expect=2e-08]; ENSG00000264364, DYNLL2, dynein light chain LC8-type 2, [Score=49.3, Expect=1e-07]} {Mouse: ENSMUSG00000009013, Dynll1, dynein light chain LC8-type 1, [Score=51.2, Expect=1e-08]; ENSMUSG00000020483, Dynll2, dynein light chain LC8-type 2, [Score=49.3, Expect=8e-08]} {Dmel: FBgn0011760, ctp, cut up, [Score=49.7, Expect=4e-08]} {Celegans: WBGene00043067, dlc-5, Dynein Light Chain, [Score=50.1, Expect=1e-07]} {Smed: dd_Smed_v6_1881_0_1, dd_Smed_v6_1881_0_1, [RH, Score=134, Expect=6e-40]} {RNA1509_3612} {RNA1310_33488} {RNA815_4208} |
9. | MligTC455_41757 | 2210 | 46.04 | Mlig455_067601 | Neo: - Age: Down-Down-Up |
1.691 | - | - | 0.716 | 0.975 | - | - | Mlig455_067601 {REF} {Length: 2908} {Pfam: Thymosin beta-4 family [PF01290.22, score=118.1]} {Dmel: FBgn0026084, cib, ciboulot, [RH, Score=58.5, Expect=6e-11]} {Celegans: WBGene00006649, tth-1, Thymosin beta, [Score=45.8, Expect=3e-06]} {Smed: dd_Smed_v6_17_0_1, dd_Smed_v6_17_0_1, [Score=73.9, Expect=5e-17]} {RNA1509_2234, RNA1509_44322, RNA1509_48105, RNA1509_57771} {RNA1310_19846.1, RNA1509_2234, RNA1509_44322, RNA1509_48105, RNA1509_57771} {RNA1509_2234, RNA1509_44322, RNA1509_48105, RNA1509_57771, RNA815_7395.2} | |
10. | MligTC455_47839 | 243 | 5.06 | Mlig455_019928 | Neo: - Age: Down-Down-Up |
1.686 | - | - | - | - | 0.953 | 0.733 | Mlig455_019928 {REF} {Length: 1993} {TRANSSPLICED} {Smed: dd_Smed_v6_9778_0_4, dd_Smed_v6_9778_0_4, [RH, Score=254, Expect=3e-83]} {RNA1509_39726} {RNA1310_16157} {RNA815_7435.1} | |
11. | MligTC455_39167 | 4053 | 84.43 | Mlig455_025669, Mlig455_044642, Mlig455_051028 | Neo: - Age: - |
DYNLRB2 | 1.663 | - | - | 0.707 | - | 0.956 | - | Mlig455_025669 {REF} {Length: 1077} Mlig455_044642 {REF} {Length: 964} {TRANSSPLICED} {Pfam: Roadblock/LC7 domain [PF03259.19, score=81.5]; Ragulator complex protein LAMTOR5 [PF16672.7, score=20.3]} {Human: ENSG00000168589, DYNLRB2, dynein light chain roadblock-type 2, [RH, Score=137, Expect=2e-43]; ENSG00000125971, DYNLRB1, dynein light chain roadblock-type 1, [RH, Score=135, Expect=2e-42]} {Mouse: ENSMUSG00000034467, Dynlrb2, dynein light chain roadblock-type 2, [RH, Score=137, Expect=1e-43]; ENSMUSG00000047459, Dynlrb1, dynein light chain roadblock-type 1, [RH, Score=132, Expect=1e-41]} {Dmel: FBgn0024196, robl, roadblock, [RH, Score=142, Expect=2e-45]} {Celegans: WBGene00012004, dyrb-1, Dynein light chain roadblock, [RH, Score=98.6, Expect=2e-28]} {Smed: dd_Smed_v6_1126_0_1, dd_Smed_v6_1126_0_1, [RH, Score=140, Expect=6e-45]} {RNA1509_33958, RNA1509_5299, RNA1509_9684} {RNA1310_35265, RNA1509_33958, RNA1509_5299, RNA1509_9684} {RNA1509_33958, RNA1509_5299, RNA1509_9684, RNA815_16397} Mlig455_051028 {REF} {Length: 545} {Pfam: PAN domain [PF00024.28, score=25.5]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=55.5, Expect=1e-09]} {RNA1509_25838} {RNA1310_43302} |
12. | MligTC455_41599 | 3357 | 69.95 | Mlig455_064396 | Neo: - |
PDZK1 | 1.657 | - | - | - | 0.950 | 0.707 | - | Mlig455_064396 {REF} {Length: 1538} {Pfam: PDZ domain [PF00595.26, score=25.5]} {Human: ENSG00000174827, PDZK1, PDZ domain containing 1, [Score=50.8, Expect=1e-06]} {Mouse: ENSMUSG00000002504, Slc9a3r2, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2, [Score=46.2, Expect=1e-05]} {Celegans: WBGene00006438, nrfl-1, NHERF (Mammalian Na/H Exchange Regulatory Factor) Like, [Score=55.1, Expect=1e-08]} {Smed: dd_Smed_v6_3039_0_1, dd_Smed_v6_3039_0_1, [Score=63.5, Expect=3e-12]} {RNA1509_4967} {RNA1310_15027} {RNA815_6549.1} |
13. | MligTC455_53802 | 483 | 10.06 | Mlig455_068495 | Neo: - Age: - |
FAM57A | 0.963 | - | - | - | 0.963 | - | - | Mlig455_068495 {REF} {Length: 2399} {Pfam: TLC domain [PF03798.18, score=86.2]} {Human: ENSG00000167695, FAM57A, family with sequence similarity 57 member A, [Score=118, Expect=3e-31]} {Mouse: ENSMUSG00000069808, Fam57a, family with sequence similarity 57, member A, [Score=127, Expect=8e-35]} {Dmel: FBgn0028480, CG17841, [Score=49.7, Expect=1e-06]} {RNA1509_50854} {RNA1310_27304.1} {RNA815_15510} |
14. | MligTC455_29517 | 224 | 4.66 | Mlig455_029414 | Neo: - Age: - Region-enriched R4: 1.973/0.03463 |
GRIA2 | 0.96 | - | - | - | 0.960 | - | - | Mlig455_029414 {REF} {Length: 4533} {Pfam: Ligand-gated ion channel [PF00060.28, score=102.7]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=60.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=22.3]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=156, Expect=9e-39]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=155, Expect=2e-38]; ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=154, Expect=5e-38]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=152, Expect=2e-37]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=156, Expect=6e-39]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=155, Expect=2e-38]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=153, Expect=7e-38]} {Dmel: FBgn0038837, CG3822, [Score=148, Expect=1e-36]} {Celegans: WBGene00001615, glr-4, GLutamate Receptor family (AMPA), [Score=132, Expect=1e-31]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=234, Expect=8e-70]} {RNA1509_31776} {RNA1310_7321.1} {RNA815_2521.1} |
15. | MligTC455_38015 | 2996 | 62.41 | Mlig455_003768, Mlig455_003780 | Neo: - Age: Down-Down-Up |
CFAP53 | 0.959 | - | - | - | - | 0.959 | - | Mlig455_003768 {REF} {Length: 3258} {Pfam: Trichohyalin-plectin-homology domain [PF13868.8, score=77.0]} {Human: ENSG00000172361, CFAP53, cilia and flagella associated protein 53, [RH, Score=172, Expect=4e-47]} {Mouse: ENSMUSG00000035394, Cfap53, cilia and flagella associated protein 53, [RH, Score=164, Expect=2e-44]} {Smed: dd_Smed_v6_3219_0_1, dd_Smed_v6_3219_0_1, [RH, Score=302, Expect=7e-97]} {RNA1509_1100, RNA1509_19749, RNA1509_56592} {RNA1310_13648, RNA1509_19749, RNA1509_56592} {RNA1509_19749, RNA1509_56592, RNA815_5728} Mlig455_003780 {REF} {Length: 2775} {Pfam: Trichohyalin-plectin-homology domain [PF13868.8, score=76.3]} {Human: ENSG00000172361, CFAP53, cilia and flagella associated protein 53, [RH, Score=171, Expect=1e-46]} {Mouse: ENSMUSG00000035394, Cfap53, cilia and flagella associated protein 53, [RH, Score=166, Expect=1e-44]} {Smed: dd_Smed_v6_3219_0_1, dd_Smed_v6_3219_0_1, [RH, Score=302, Expect=9e-97]} {RNA1509_1100, RNA1509_14187} {RNA1310_13648, RNA1509_14187} {RNA1509_14187, RNA815_5728} |
16. | MligTC455_46748 | 216 | 4.51 | Mlig455_012842 | Neo: - Age: Down-Up-Up |
0.959 | - | - | - | 0.959 | - | - | Mlig455_012842 {REF} {Length: 1460} {Pfam: MIT (microtubule interacting and transport) domain [PF04212.20, score=25.1]} {RNA1310_28416.2} {RNA815_36900} | |
17. | MligTC455_37359 | 688 | 14.34 | Mlig455_029540 | Neo: - |
CFAP52 | 0.956 | - | - | - | 0.956 | - | - | Mlig455_029540 {REF} {Length: 2517} {Pfam: WD domain, G-beta repeat [PF00400.34, score=123.9]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=42.1]; WD40-like domain [PF17005.7, score=27.1]} {Human: ENSG00000166596, CFAP52, cilia and flagella associated protein 52, [RH, Score=750, Expect=0.0]} {Mouse: ENSMUSG00000020904, Cfap52, cilia and flagella associated protein 52, [RH, Score=757, Expect=0.0]} {Dmel: FBgn0035724, CG10064, [RH, Score=441, Expect=1e-145]} {Celegans: WBGene00004895, smu-1, SMU-1; Suppressor of Mec and Unc defects, [Score=60.5, Expect=2e-09]} {Smed: dd_Smed_v6_2585_0_1, dd_Smed_v6_2585_0_1, [RH, Score=841, Expect=0.0]} {RNA1509_1341} {RNA1310_8859} {RNA815_2855} |
18. | MligTC455_23866 | 384 | 8.01 | Mlig455_002342 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=0.442 Region-enriched R5: 1.898/0.04942 |
MARS2 | 0.955 | - | - | - | - | 0.955 | - | Mlig455_002342 {REF} {Length: 2569} {TRANSSPLICED} {Pfam: tRNA synthetases class I (M) [PF09334.13, score=211.4]; tRNA synthetases class I (I, L, M and V) [PF00133.24, score=33.0]; Anticodon binding domain of methionyl tRNA ligase [PF19303.1, score=19.0]} {Human: ENSG00000247626, MARS2, methionyl-tRNA synthetase 2, mitochondrial, [Score=301, Expect=7e-95]} {Mouse: ENSMUSG00000046994, Mars2, methionine-tRNA synthetase 2 (mitochondrial), [Score=291, Expect=2e-91]} {Dmel: FBgn0027083, MetRS-m, Methionyl-tRNA synthetase, mitochondrial, [Score=310, Expect=6e-99]} {Celegans: WBGene00013678, Y105E8A.20, Methionyl-tRNA synthetase (Mitochondrial), [Score=291, Expect=3e-92]} {Smed: dd_Smed_v6_12525_0_2, dd_Smed_v6_12525_0_2, [Score=276, Expect=1e-86]} {RNA1509_34702} {RNA1310_17351} {RNA815_6878} |
19. | MligTC455_18647 | 1244 | 25.91 | Mlig455_063436 | Neo: - Age: - |
0.953 | - | - | - | 0.953 | - | - | Mlig455_063436 {REF} {Length: 1503} {Pfam: BTB/POZ domain [PF00651.33, score=34.7]} {RNA1509_43600, RNA1509_45066} {RNA1310_23212, RNA1509_43600, RNA1509_45066} {RNA1509_43600, RNA1509_45066, RNA815_2283.1} | |
20. | MligTC455_49234 | 529 | 11.02 | Mlig455_022147 | Neo: - Age: Up-Down-Down Region-enriched R5: 1.228/0.00988 |
DOCK7 | 0.952 | - | - | - | - | 0.952 | - | Mlig455_022147 {REF} {Length: 9628} {TRANSSPLICED} {Pfam: Dock homology region 2 [PF06920.15, score=602.4]; C2 domain in Dock180 and Zizimin proteins [PF14429.8, score=135.7]} {Human: ENSG00000116641, DOCK7, dedicator of cytokinesis 7, [RH, Score=721, Expect=0.0]; ENSG00000130158, DOCK6, dedicator of cytokinesis 6, [RH, Score=696, Expect=0.0]} {Mouse: ENSMUSG00000028556, Dock7, dedicator of cytokinesis 7, [RH, Score=722, Expect=0.0]} {Dmel: FBgn0031216, Zir, Zizimin-related, [RH, Score=687, Expect=0.0]} {Celegans: WBGene00018520, F46H5.4, [RH, Score=418, Expect=3e-119]} {Smed: dd_Smed_v6_11826_0_1, dd_Smed_v6_11826_0_1, [RH, Score=600, Expect=0.0]} {RNA1509_5744} {RNA1310_435, RNA1509_5744} {RNA1509_5744, RNA815_1936} |