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Results for MligTC455_44916

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_44916 688 14.33 Mlig455_025259

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.436

GMPPA Mlig455_025259 {REF} {Length: 1859} {TRANSSPLICED} {Pfam: Nucleotidyl transferase [PF00483.25, score=97.0]; Bacterial transferase hexapeptide (six repeats) [PF00132.26, score=29.6]; MobA-like NTP transferase domain [PF12804.9, score=21.3]} {Human: ENSG00000144591, GMPPA, GDP-mannose pyrophosphorylase A, [RH, Score=458, Expect=1e-159]} {Mouse: ENSMUSG00000033021, Gmppa, GDP-mannose pyrophosphorylase A, [RH, Score=461, Expect=4e-161]} {Dmel: FBgn0034035, CG8207, [RH, Score=450, Expect=1e-156]} {Celegans: WBGene00021628, Y47D9A.1, [RH, Score=398, Expect=9e-137]} {Smed: dd_Smed_v6_4150_0_1, dd_Smed_v6_4150_0_1, [RH, Score=496, Expect=6e-175]} {RNA1509_37379} {RNA1310_15544, RNA1509_37379} {RNA1509_37379, RNA815_10312.2}

Cumulative graph for MligTC455_44916

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.639 4.124 0.33985 0.98504
RegionR2 -0.023 4.124 0.97260 1.00000
RegionR3 0.015 4.124 0.96447 1.00000
RegionR4 0.974 4.124 0.02480 0.11862
RegionR5 0.951 4.124 0.00603 0.03996
RegionR6 0.342 4.124 0.42647 0.99180
RegionR7 0.404 4.124 0.49004 1.00000
RegionR8 -1.023 4.124 0.29576 0.92507

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 1.228 4.124 0.57712 1.00000
RegenerationR2 0.561 4.124 0.07908 0.45359
RegenerationR3 0.593 4.124 0.10337 0.51026
RegenerationR4 0.105 4.124 0.75969 0.97266
RegenerationR5 0.377 4.124 0.19817 0.63052
RegenerationR6 0.52 4.124 0.14619 0.46825
RegenerationBL 1.033 4.124 0.03846 0.22241
RegenerationTP 0.597 4.124 0.36360 0.80305


Genes with expression patterns similar to MligTC455_44916

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_44916 688 14.33 Mlig455_025259

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.436

GMPPA 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_025259 {REF} {Length: 1859} {TRANSSPLICED} {Pfam: Nucleotidyl transferase [PF00483.25, score=97.0]; Bacterial transferase hexapeptide (six repeats) [PF00132.26, score=29.6]; MobA-like NTP transferase domain [PF12804.9, score=21.3]} {Human: ENSG00000144591, GMPPA, GDP-mannose pyrophosphorylase A, [RH, Score=458, Expect=1e-159]} {Mouse: ENSMUSG00000033021, Gmppa, GDP-mannose pyrophosphorylase A, [RH, Score=461, Expect=4e-161]} {Dmel: FBgn0034035, CG8207, [RH, Score=450, Expect=1e-156]} {Celegans: WBGene00021628, Y47D9A.1, [RH, Score=398, Expect=9e-137]} {Smed: dd_Smed_v6_4150_0_1, dd_Smed_v6_4150_0_1, [RH, Score=496, Expect=6e-175]} {RNA1509_37379} {RNA1310_15544, RNA1509_37379} {RNA1509_37379, RNA815_10312.2}
2. MligTC455_18654 497 10.36 Mlig455_032693

Neo: -

Age: -

PPME1 3.467 0.891 - - 0.980 0.785 0.811 Mlig455_032693 {REF} {Length: 2557} {TRANSSPLICED} {Pfam: Alpha/beta hydrolase family [PF12697.9, score=84.1]; alpha/beta hydrolase fold [PF00561.22, score=34.3]; Serine aminopeptidase, S33 [PF12146.10, score=30.6]; alpha/beta hydrolase fold [PF07859.15, score=20.5]; PGAP1-like protein [PF07819.15, score=19.9]} {Human: ENSG00000214517, PPME1, protein phosphatase methylesterase 1, [RH, Score=273, Expect=6e-87]} {Mouse: ENSMUSG00000030718, Ppme1, protein phosphatase methylesterase 1, [RH, Score=157, Expect=3e-43]} {Dmel: FBgn0035951, CG5068, [RH, Score=262, Expect=6e-83]} {Celegans: WBGene00007188, B0464.9, Probable protein phosphatase methylesterase 1, [RH, Score=147, Expect=4e-40]} {Smed: dd_Smed_v6_5813_0_1, dd_Smed_v6_5813_0_1, [RH, Score=291, Expect=1e-94]} {RNA1509_18678, RNA1509_50525} {RNA1310_14476, RNA1509_50525} {RNA1509_50525, RNA815_3742.1}
3. MligTC455_18948 2094 43.62 Mlig455_051458, Mlig455_066688

Neo: -

Age: logFC(26M/2M)=0.543

METTL8 3.3 - - 0.712 0.955 0.769 0.864

Mlig455_051458 {REF} {Length: 1291} {TRANSSPLICED} {Pfam: Methyltransferase domain [PF13489.8, score=43.3]; Methyltransferase domain [PF13649.8, score=31.2]; Methyltransferase domain [PF08242.14, score=29.3]; Methyltransferase domain [PF08241.14, score=20.7]} {Human: ENSG00000123600, METTL8, methyltransferase like 8, [RH, Score=181, Expect=2e-53]; ENSG00000087995, METTL2A, methyltransferase like 2A, [RH, Score=181, Expect=3e-54]; ENSG00000165055, METTL2B, methyltransferase like 2B, [RH, Score=180, Expect=6e-54]} {Mouse: ENSMUSG00000020691, Mettl2, methyltransferase like 2, [RH, Score=219, Expect=1e-68]} {Dmel: FBgn0035247, metl, methyltransferase-like, [RH, Score=241, Expect=7e-78]} {Celegans: WBGene00044720, metl-2, MEthylTransferase Like, [RH, Score=235, Expect=8e-76]} {Smed: dd_Smed_v6_3413_0_1, dd_Smed_v6_3413_0_1, [RH, Score=248, Expect=2e-81]} {RNA1509_6032} {RNA1310_26875} {RNA815_11503}

Mlig455_066688 {REF} {Length: 1292} {TRANSSPLICED} {Pfam: Methyltransferase domain [PF13489.8, score=43.3]; Methyltransferase domain [PF13649.8, score=31.2]; Methyltransferase domain [PF08242.14, score=29.3]; Methyltransferase domain [PF08241.14, score=20.7]} {Human: ENSG00000123600, METTL8, methyltransferase like 8, [RH, Score=181, Expect=2e-53]; ENSG00000087995, METTL2A, methyltransferase like 2A, [RH, Score=181, Expect=3e-54]; ENSG00000165055, METTL2B, methyltransferase like 2B, [RH, Score=180, Expect=6e-54]} {Mouse: ENSMUSG00000020691, Mettl2, methyltransferase like 2, [RH, Score=219, Expect=1e-68]} {Dmel: FBgn0035247, metl, methyltransferase-like, [RH, Score=241, Expect=7e-78]} {Celegans: WBGene00044720, metl-2, MEthylTransferase Like, [RH, Score=235, Expect=8e-76]} {Smed: dd_Smed_v6_3413_0_1, dd_Smed_v6_3413_0_1, [RH, Score=248, Expect=2e-81]} {RNA1509_6032} {RNA1310_26875, RNA1509_6032} {RNA1509_6032, RNA815_11503}
4. MligTC455_31597 1057 22.03 Mlig455_051131, Mlig455_051132

Neo: -

Age: -

DNM1 3.281 0.778 - - 0.972 0.778 0.753

Mlig455_051131 {REF} {Length: 4617} {Pfam: Dynamin central region [PF01031.22, score=339.1]; Dynamin family [PF00350.25, score=186.1]; Dynamin GTPase effector domain [PF02212.20, score=82.9]; PH domain [PF00169.31, score=40.0]; 50S ribosome-binding GTPase [PF01926.25, score=19.5]} {Human: ENSG00000106976, DNM1, dynamin 1, [RH, Score=1129, Expect=0.0]; ENSG00000197959, DNM3, dynamin 3, [RH, Score=1099, Expect=0.0]; ENSG00000079805, DNM2, dynamin 2, [RH, Score=1085, Expect=0.0]} {Mouse: ENSMUSG00000026825, Dnm1, dynamin 1, [RH, Score=1126, Expect=0.0]; ENSMUSG00000040265, Dnm3, dynamin 3, [RH, Score=1100, Expect=0.0]; ENSMUSG00000033335, Dnm2, dynamin 2, [RH, Score=1086, Expect=0.0]} {Dmel: FBgn0003392, shi, shibire, [RH, Score=1052, Expect=0.0]} {Celegans: WBGene00001130, dyn-1, Dynamin, [RH, Score=995, Expect=0.0]} {Smed: dd_Smed_v6_6863_0_1, dd_Smed_v6_6863_0_1, [RH, Score=1077, Expect=0.0]} {RNA1509_2804, RNA1509_37430} {RNA1310_1586.1, RNA1509_2804, RNA1509_37430} {RNA1509_2804, RNA1509_37430, RNA815_6662.1}

Mlig455_051132 {REF} {Length: 4542} {Pfam: Domain of unknown function (DUF4081) [PF13312.8, score=21.6]} {RNA1509_46947} {RNA1310_33451} {RNA815_26447.1}
5. MligTC455_16411 424 8.83 Mlig455_060581

Neo: -

Age: -

3.202 - 0.723 - 0.980 0.768 0.731 Mlig455_060581 {REF} {Length: 1656} {TRANSSPLICED} {RNA1509_40255, RNA1509_49687} {RNA1310_29185, RNA1509_40255, RNA1509_49687} {RNA1509_40255, RNA1509_49687, RNA815_14786}
6. MligTC455_35423 1070 22.28 Mlig455_043797

Neo: Int S/G2/M

Age: Up-Down-Up

DIMT1 2.682 - - - 0.963 0.926 0.793 Mlig455_043797 {REF} {Length: 1409} {TRANSSPLICED} {Pfam: Ribosomal RNA adenine dimethylase [PF00398.22, score=216.0]; Methyltransferase domain [PF13649.8, score=31.6]; Methyltransferase domain [PF08241.14, score=21.8]; Methyltransferase small domain [PF05175.16, score=20.2]; Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) [PF01135.21, score=20.0]} {Human: ENSG00000086189, DIMT1, DIM1 dimethyladenosine transferase 1 homolog, [RH, Score=350, Expect=8e-121]} {Mouse: ENSMUSG00000021692, Dimt1, DIM1 dimethyladenosine transferase 1-like (S. cerevisiae), [RH, Score=351, Expect=3e-121]} {Dmel: FBgn0039627, CG11837, [RH, Score=361, Expect=2e-125]} {Celegans: WBGene00008455, E02H1.1, Probable dimethyladenosine transferase, [RH, Score=333, Expect=2e-114]} {Smed: dd_Smed_v6_5268_0_1, dd_Smed_v6_5268_0_1, [RH, Score=337, Expect=9e-116]} {RNA1509_18691, RNA1509_9015} {RNA1310_23608.1, RNA1509_18691, RNA1509_9015} {RNA1509_18691, RNA1509_9015, RNA815_9867}
7. MligTC455_48173 476 9.92 Mlig455_070590

Neo: -

Age: Down-Down-Up

Region-enriched R5: 1.972/0.02001

2.673 - - 0.860 0.965 - 0.848 Mlig455_070590 {REF} {Length: 2721} {TRANSSPLICED} {Pfam: Class II Aldolase and Adducin N-terminal domain [PF00596.23, score=21.5]} {RNA1509_10052} {RNA1310_26586} {RNA815_22348}
8. MligTC455_36484 730 15.2 Mlig455_008622

Neo: -

Age: -

TAF5 2.653 0.875 - - 0.954 - 0.824 Mlig455_008622 {REF} {Length: 5592} {Pfam: WD domain, G-beta repeat [PF00400.34, score=123.9]; WD40 associated region in TFIID subunit, NTD2 domain [PF04494.17, score=90.6]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=41.2]; WD40 region of Ge1, enhancer of mRNA-decapping protein [PF16529.7, score=17.8]} {Human: ENSG00000148835, TAF5, TATA-box binding protein associated factor 5, [RH, Score=426, Expect=2e-138]} {Mouse: ENSMUSG00000025049, Taf5, TATA-box binding protein associated factor 5, [RH, Score=426, Expect=9e-139]} {Dmel: FBgn0010356, Taf5, TBP-associated factor 5, [RH, Score=380, Expect=2e-122]} {Celegans: WBGene00006386, taf-5, TAF (TBP-associated transcription factor) family, [RH, Score=254, Expect=3e-75]} {Smed: dd_Smed_v6_7319_0_1, dd_Smed_v6_7319_0_1, [RH, Score=311, Expect=2e-96]} {RNA1509_15120} {RNA1310_12001, RNA1509_15120} {RNA1509_15120, RNA815_9687}
9. MligTC455_26250 539 11.22 Mlig455_040375

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=2.676

Region-enriched R4: 1.485/0.00739

AFG1L 2.638 - - 0.753 - 0.928 0.957 Mlig455_040375 {REF} {Length: 1985} {TRANSSPLICED} {Pfam: AFG1-like ATPase [PF03969.18, score=283.5]} {Human: ENSG00000135537, AFG1L, AFG1 like ATPase, [Score=310, Expect=4e-100]} {Mouse: ENSMUSG00000038302, Afg1l, AFG1 like ATPase, [Score=298, Expect=6e-96]} {Dmel: FBgn0033734, CG8520, [Score=303, Expect=5e-98]} {Celegans: WBGene00016261, C30F12.2, [Score=294, Expect=7e-95]} {Smed: dd_Smed_v6_4382_0_4, dd_Smed_v6_4382_0_4, [Score=288, Expect=9e-93]} {RNA1509_28953, RNA1509_29381} {RNA1310_17455, RNA1509_28953, RNA1509_29381} {RNA1509_28953, RNA1509_29381, RNA815_7977}
10. MligTC455_50228 1128 23.5 Mlig455_016788, Mlig455_016809

Neo: -

Age: -

RAB5B 2.632 0.819 - - 0.958 - 0.855

Mlig455_016788 {REF} {Length: 1792} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=200.6]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=122.1]; ADP-ribosylation factor family [PF00025.23, score=50.5]; 50S ribosome-binding GTPase [PF01926.25, score=25.7]; Gtr1/RagA G protein conserved region [PF04670.14, score=22.8]; RsgA GTPase [PF03193.18, score=19.5]} {Human: ENSG00000111540, RAB5B, RAB5B, member RAS oncogene family, [RH, Score=281, Expect=1e-96]; ENSG00000108774, RAB5C, RAB5C, member RAS oncogene family, [RH, Score=278, Expect=6e-95]; ENSG00000144566, RAB5A, RAB5A, member RAS oncogene family, [RH, Score=275, Expect=4e-94]} {Mouse: ENSMUSG00000000711, Rab5b, RAB5B, member RAS oncogene family, [RH, Score=281, Expect=7e-97]; ENSMUSG00000019173, Rab5c, RAB5C, member RAS oncogene family, [RH, Score=277, Expect=2e-95]; ENSMUSG00000017831, Rab5a, RAB5A, member RAS oncogene family, [RH, Score=275, Expect=2e-94]} {Dmel: FBgn0014010, Rab5, [RH, Score=275, Expect=2e-94]} {Celegans: WBGene00004268, rab-5, RAB family, [RH, Score=275, Expect=8e-95]} {Smed: dd_Smed_v6_796_0_1, dd_Smed_v6_796_0_1, [RH, Score=278, Expect=2e-96]} {RNA1509_2296, RNA1509_42263} {RNA1310_25305, RNA1509_42263} {RNA1509_42263, RNA815_10567}

Mlig455_016809 {REF} {Length: 1784} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=200.6]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=122.1]; ADP-ribosylation factor family [PF00025.23, score=50.5]; 50S ribosome-binding GTPase [PF01926.25, score=25.7]; Gtr1/RagA G protein conserved region [PF04670.14, score=22.8]; RsgA GTPase [PF03193.18, score=19.5]} {Human: ENSG00000111540, RAB5B, RAB5B, member RAS oncogene family, [RH, Score=281, Expect=1e-96]; ENSG00000108774, RAB5C, RAB5C, member RAS oncogene family, [RH, Score=278, Expect=6e-95]; ENSG00000144566, RAB5A, RAB5A, member RAS oncogene family, [RH, Score=275, Expect=4e-94]} {Mouse: ENSMUSG00000000711, Rab5b, RAB5B, member RAS oncogene family, [RH, Score=281, Expect=7e-97]; ENSMUSG00000019173, Rab5c, RAB5C, member RAS oncogene family, [RH, Score=277, Expect=2e-95]; ENSMUSG00000017831, Rab5a, RAB5A, member RAS oncogene family, [RH, Score=275, Expect=2e-94]} {Dmel: FBgn0014010, Rab5, [RH, Score=275, Expect=2e-94]} {Celegans: WBGene00004268, rab-5, RAB family, [RH, Score=275, Expect=8e-95]} {Smed: dd_Smed_v6_796_0_1, dd_Smed_v6_796_0_1, [RH, Score=278, Expect=2e-96]} {RNA1509_2296} {RNA1310_25305, RNA1509_2296} {RNA1509_2296, RNA815_10567}
11. MligTC455_40366 1075 22.39 Mlig455_003182, Mlig455_003384

Neo: Neoblast, stringent

Age: -

Region-enriched R5: 2.088/0.00106
Region-enriched R4: 1.952/0.01523

WDHD1 2.629 - - - 0.972 0.801 0.856

Mlig455_003182 {REF} {Length: 5013} {Pfam: Minichromosome loss protein, Mcl1, middle region [PF12341.10, score=152.4]; WD domain, G-beta repeat [PF00400.34, score=49.2]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=22.7]} {Human: ENSG00000198554, WDHD1, WD repeat and HMG-box DNA binding protein 1, [RH, Score=138, Expect=9e-33]} {Mouse: ENSMUSG00000037572, Wdhd1, WD repeat and HMG-box DNA binding protein 1, [RH, Score=137, Expect=1e-32]} {Dmel: FBgn0033890, Ctf4, Chromosome transmission fidelity 4, [RH, Score=107, Expect=2e-23]} {Celegans: WBGene00013862, wdr-5.3, WD repeat-containing protein wdr-5.3, [Score=57.4, Expect=3e-08]} {Smed: dd_Smed_v6_19827_0_1, dd_Smed_v6_19827_0_1, [Score=48.5, Expect=1e-05]} {RNA1509_9571} {RNA1310_2526.2} {RNA815_1263}

Mlig455_003384 {REF} {Length: 5055} {Pfam: Minichromosome loss protein, Mcl1, middle region [PF12341.10, score=153.6]; WD domain, G-beta repeat [PF00400.34, score=49.2]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=22.7]} {Human: ENSG00000198554, WDHD1, WD repeat and HMG-box DNA binding protein 1, [RH, Score=139, Expect=5e-33]} {Mouse: ENSMUSG00000037572, Wdhd1, WD repeat and HMG-box DNA binding protein 1, [RH, Score=138, Expect=7e-33]} {Dmel: FBgn0033890, Ctf4, Chromosome transmission fidelity 4, [RH, Score=108, Expect=1e-23]} {Celegans: WBGene00013862, wdr-5.3, WD repeat-containing protein wdr-5.3, [Score=57.4, Expect=3e-08]} {Smed: dd_Smed_v6_19827_0_1, dd_Smed_v6_19827_0_1, [Score=48.5, Expect=1e-05]} {RNA1509_9571} {RNA1310_2526.2, RNA1509_9571} {RNA1509_9571, RNA815_1263}
12. MligTC455_41222 503 10.48 Mlig455_008819, Mlig455_008917

Neo: Int S/G2/M

Age: Down-Up-Up

Region-enriched R5: 2.661/0.00033

UBE2T 2.619 0.940 - - 0.960 - 0.719

Mlig455_008819 {REF} {Length: 1153} {TRANSSPLICED} {Pfam: Ubiquitin-conjugating enzyme [PF00179.28, score=127.8]} {Human: ENSG00000077152, UBE2T, ubiquitin conjugating enzyme E2 T, [RH, Score=166, Expect=2e-51]} {Mouse: ENSMUSG00000026429, Ube2t, ubiquitin-conjugating enzyme E2T, [RH, Score=149, Expect=4e-45]} {Dmel: FBgn0000173, ben, bendless, [Score=129, Expect=4e-38]} {Celegans: WBGene00006708, ubc-13, Ubiquitin-conjugating enzyme E2 13, [Score=134, Expect=7e-40]} {Smed: dd_Smed_v6_1075_0_1, dd_Smed_v6_1075_0_1, [Score=130, Expect=1e-38]} {RNA1509_29240} {RNA1310_31665} {RNA815_39037}

Mlig455_008917 {REF} {Length: 1154} {TRANSSPLICED} {Pfam: Ubiquitin-conjugating enzyme [PF00179.28, score=127.8]} {Human: ENSG00000077152, UBE2T, ubiquitin conjugating enzyme E2 T, [RH, Score=166, Expect=2e-51]} {Mouse: ENSMUSG00000026429, Ube2t, ubiquitin-conjugating enzyme E2T, [RH, Score=149, Expect=4e-45]} {Dmel: FBgn0000173, ben, bendless, [Score=129, Expect=4e-38]} {Celegans: WBGene00006708, ubc-13, Ubiquitin-conjugating enzyme E2 13, [Score=134, Expect=7e-40]} {Smed: dd_Smed_v6_1075_0_1, dd_Smed_v6_1075_0_1, [Score=130, Expect=1e-38]} {RNA1509_29240} {RNA1310_31665} {RNA815_39037}
13. MligTC455_21508 482 10.04 Mlig455_014145

Neo: -

Age: -

Region-enriched R4: 2.303/0.00747
Region-enriched R5: 1.932/0.00323

CERS1 2.608 - - 0.832 0.975 - 0.801 Mlig455_014145 {REF} {Length: 2769} {TRANSSPLICED} {Pfam: TLC domain [PF03798.18, score=110.9]} {Human: ENSG00000223802, CERS1, ceramide synthase 1, [Score=197, Expect=4e-60]} {Mouse: ENSMUSG00000087408, Cers1, ceramide synthase 1, [Score=199, Expect=7e-61]} {Dmel: FBgn0040918, schlank, [Score=89.4, Expect=1e-19]} {Celegans: WBGene00006505, lagr-1, Probable ceramide synthase lagr-1, [RH, Score=160, Expect=6e-46]} {Smed: dd_Smed_v6_3137_0_1, dd_Smed_v6_3137_0_1, [RH, Score=296, Expect=2e-98]} {RNA1509_11009, RNA1509_50586, RNA1509_52158} {RNA1310_7542.1, RNA1509_11009, RNA1509_50586, RNA1509_52158} {RNA1509_11009, RNA1509_50586, RNA1509_52158, RNA815_1923.1}
14. MligTC455_22642 448 9.32 Mlig455_059180

Neo: Neoblast, stringent

Age: -

Region-enriched R5: 2.279/0.04360

DCTD 2.591 0.821 - - 0.977 - 0.793 Mlig455_059180 {REF} {Length: 3732} {TRANSSPLICED} {Pfam: Cytidine and deoxycytidylate deaminase zinc-binding region [PF00383.25, score=97.2]; MafB19-like deaminase [PF14437.8, score=59.1]} {Human: ENSG00000129187, DCTD, dCMP deaminase, [RH, Score=230, Expect=2e-77]} {Mouse: ENSMUSG00000031562, Dctd, dCMP deaminase, [RH, Score=237, Expect=2e-80]} {Dmel: FBgn0036959, CG6951, [RH, Score=199, Expect=2e-65]} {Celegans: WBGene00014034, ZK643.2, Probable deoxycytidylate deaminase, [RH, Score=135, Expect=3e-40]} {Smed: dd_Smed_v6_6803_0_1, dd_Smed_v6_6803_0_1, [RH, Score=200, Expect=4e-66]} {RNA1509_46940, RNA1509_56786} {RNA1310_47977, RNA1509_46940, RNA1509_56786} {RNA1509_46940, RNA1509_56786, RNA815_14734.2}
15. MligTC455_24176 656 13.67 Mlig455_034193

Neo: -

Age: -

PC 2.588 0.869 - 0.758 0.961 - - Mlig455_034193 {REF} {Length: 2105} {Pfam: Conserved carboxylase domain [PF02436.20, score=162.2]; Biotin-requiring enzyme [PF00364.24, score=59.6]; Biotin-lipoyl like [PF13533.8, score=28.4]; HlyD family secretion protein [PF13437.8, score=24.7]; Na(+)-translocating NADH-quinone reductase subunit A (NQRA) [PF05896.13, score=24.0]} {Human: ENSG00000173599, PC, pyruvate carboxylase, [Score=281, Expect=2e-86]} {Mouse: ENSMUSG00000024892, Pcx, pyruvate carboxylase, [Score=281, Expect=9e-87]} {Dmel: FBgn0027580, PCB, Pyruvate carboxylase, [Score=296, Expect=1e-92]} {Celegans: WBGene00004258, pyc-1, Pyruvate carboxylase 1, [Score=290, Expect=4e-94]} {Smed: dd_Smed_v6_2393_0_1, dd_Smed_v6_2393_0_1, [Score=299, Expect=2e-93]} {RNA1509_30437} {RNA1310_1164.1} {RNA815_728}
16. MligTC455_27190 686 14.3 Mlig455_069689

Neo: -

Age: -

Region-enriched R5: 2.147/0.01781

Regeneration-upregulated BL: 2.726

Regeneration-enriched BL: 2.726

RIOX1 2.584 - 0.750 0.873 - 0.961 - Mlig455_069689 {REF} {Length: 1997} {TRANSSPLICED} {Pfam: Cupin superfamily protein [PF08007.14, score=211.7]; Cupin-like domain [PF13621.8, score=27.0]} {Human: ENSG00000170468, RIOX1, ribosomal oxygenase 1, [RH, Score=397, Expect=2e-130]} {Mouse: ENSMUSG00000046791, Riox1, ribosomal oxygenase 1, [RH, Score=395, Expect=6e-130]} {Dmel: FBgn0266570, CG2982, [RH, Score=329, Expect=3e-104]} {Celegans: WBGene00020902, jmjc-1, Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66, [RH, Score=273, Expect=4e-82]} {RNA1509_19703} {RNA1310_13539, RNA1509_19703} {RNA1509_19703, RNA815_7796}
17. MligTC455_48055 271 5.65 Mlig455_059256

Neo: -

Age: -

2.566 - - - 0.958 0.713 0.895 Mlig455_059256 {REF} {Length: 4894} {Pfam: PX domain [PF00787.26, score=33.5]} {RNA1509_29567, RNA1509_47008} {RNA1310_1542.1, RNA1509_47008} {RNA1509_47008, RNA815_21449}
18. MligTC455_50452 856 17.83 Mlig455_061011

Neo: -

Age: -

Region-enriched R4: 1.811/0.02245
Region-enriched R5: 1.589/0.02679

GPD2 2.552 0.953 - 0.816 - 0.783 - Mlig455_061011 {REF} {Length: 2921} {TRANSSPLICED} {Pfam: FAD dependent oxidoreductase [PF01266.26, score=183.6]; C-terminal domain of alpha-glycerophosphate oxidase [PF16901.7, score=132.8]; EF-hand domain pair [PF13499.8, score=50.9]; FAD binding domain [PF00890.26, score=39.3]; EF hand [PF00036.34, score=35.9]; EF-hand domain [PF13405.8, score=32.7]; EF-hand domain pair [PF13833.8, score=28.8]; EF hand [PF13202.8, score=28.6]; FAD dependent oxidoreductase [PF12831.9, score=25.8]; FAD binding domain [PF01494.21, score=21.8]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=20.0]; Glucose inhibited division protein A [PF01134.24, score=19.8]} {Human: ENSG00000115159, GPD2, glycerol-3-phosphate dehydrogenase 2, [RH, Score=863, Expect=0.0]} {Mouse: ENSMUSG00000026827, Gpd2, glycerol phosphate dehydrogenase 2, mitochondrial, [RH, Score=847, Expect=0.0]} {Dmel: FBgn0022160, Gpo-1, Glycerophosphate oxidase-1, [RH, Score=822, Expect=0.0]} {Celegans: WBGene00012031, T25G3.4, Probable glycerol-3-phosphate dehydrogenase, mitochondrial, [RH, Score=776, Expect=0.0]} {Smed: dd_Smed_v6_4928_0_1, dd_Smed_v6_4928_0_1, [RH, Score=830, Expect=0.0]} {RNA1509_31434, RNA1509_3796} {RNA1310_6250.1, RNA1509_31434, RNA1509_3796} {RNA1509_31434, RNA1509_3796, RNA815_1850.1}
19. MligTC455_51579 550 11.47 Mlig455_042559

Neo: Int S/G2/M

Age: Down-Up-Up, logFC(26M/2M)=0.292

DIS3L 2.543 - - - 0.960 0.864 0.719 Mlig455_042559 {REF} {Length: 3524} {TRANSSPLICED} {Pfam: RNB domain [PF00773.21, score=268.4]; Dis3-like cold-shock domain 2 (CSD2) [PF17849.3, score=74.6]; Rrp44-like cold shock domain [PF17216.5, score=28.1]; Cold shock domain [PF17876.3, score=23.3]; S1 domain [PF17215.5, score=19.3]} {Human: ENSG00000166938, DIS3L, DIS3 like exosome 3'-5' exoribonuclease, [RH, Score=869, Expect=0.0]} {Mouse: ENSMUSG00000032396, Dis3l, DIS3 like exosome 3'-5' exoribonuclease, [RH, Score=872, Expect=0.0]} {Dmel: FBgn0039183, Dis3, [RH, Score=509, Expect=2e-163]} {Celegans: WBGene00001001, dis-3, Probable exosome complex exonuclease RRP44, [RH, Score=451, Expect=8e-142]} {Smed: dd_Smed_v6_6527_0_1, dd_Smed_v6_6527_0_1, [RH, Score=914, Expect=0.0]} {RNA1509_5285} {RNA1310_3365, RNA1509_5285} {RNA1509_5285, RNA815_3022}
20. MligTC455_47457 243 5.05 Mlig455_052731

Neo: -

Age: -

Region-enriched R5: 2.068/0.00294

LETMD1 2.541 - - - 0.972 0.795 0.774 Mlig455_052731 {REF} {Length: 1802} {TRANSSPLICED} {Pfam: LETM1-like protein [PF07766.15, score=96.7]} {Human: ENSG00000050426, LETMD1, LETM1 domain containing 1, [RH, Score=64.3, Expect=4e-11]} {Mouse: ENSMUSG00000037353, Letmd1, LETM1 domain containing 1, [RH, Score=57.8, Expect=5e-09]} {Dmel: FBgn0017429, CG5989, [RH, Score=101, Expect=1e-23]} {Celegans: WBGene00009276, F30F8.9, [Score=47.4, Expect=6e-06]} {RNA1509_25725, RNA1509_53190} {RNA1310_16676, RNA1509_25725, RNA1509_53190} {RNA1509_25725, RNA1509_53190, RNA815_13513}
21. MligTC455_52386 364 7.59 Mlig455_023406

Neo: -

Age: -

2.536 - - 0.803 0.958 - 0.775 Mlig455_023406 {REF} {Length: 701} {TRANSSPLICED} {Pfam: Tim10/DDP family zinc finger [PF02953.17, score=44.4]} {Dmel: FBgn0027358, Tim9b, Translocase of inner membrane 9b, [Score=40.8, Expect=1e-05]} {Celegans: WBGene00006572, tin-9.1, Mitochondrial import inner membrane translocase subunit Tim9, [Score=50.8, Expect=8e-10]} {RNA1509_22097} {RNA1310_16763} {RNA815_6211.1}
22. MligTC455_45331 646 13.45 Mlig455_038588

Neo: -

Age: -

Region-enriched R5: 1.393/0.04906

2.535 - - 0.700 0.973 - 0.862 Mlig455_038588 {REF} {Length: 766} {TRANSSPLICED} {RNA1509_11471} {RNA1310_45904} {RNA815_20936.2}
23. MligTC455_21886 383 7.97 Mlig455_009535

Neo: -

Age: Up-Down-Down

NUMB 2.534 - - - 0.978 0.766 0.790 Mlig455_009535 {REF} {Length: 5350} {TRANSSPLICED} {Pfam: Phosphotyrosine interaction domain (PTB/PID) [PF00640.25, score=82.7]; Phosphotyrosine interaction domain (PTB/PID) [PF14719.8, score=21.7]} {Human: ENSG00000133961, NUMB, NUMB, endocytic adaptor protein, [RH, Score=238, Expect=6e-71]} {Mouse: ENSMUSG00000021224, Numb, NUMB endocytic adaptor protein, [Score=238, Expect=6e-71]; ENSMUSG00000063160, Numbl, numb-like, [Score=230, Expect=3e-68]} {Dmel: FBgn0002973, numb, [RH, Score=278, Expect=5e-87]} {Celegans: WBGene00003830, num-1, Numb-related protein 1, [RH, Score=249, Expect=7e-76]} {Smed: dd_Smed_v6_8303_0_1, dd_Smed_v6_8303_0_1, [RH, Score=311, Expect=5e-101]} {RNA1509_13393, RNA1509_53213} {RNA1310_17117, RNA1509_53213} {RNA1509_53213, RNA815_12313}
24. MligTC455_32602 2591 53.97 Mlig455_037151, Mlig455_038500, Mlig455_052299

Neo: -

Age: -

Region-enriched R5: 1.190/0.00001
Region-enriched R4: 1.043/0.00363

RAB2A, RAB2B 2.527 - - - 0.957 0.761 0.809

Mlig455_037151 {REF} {Length: 4493} {Pfam: Ras family [PF00071.24, score=202.2]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=108.8]; Lecithin retinol acyltransferase [PF04970.15, score=58.4]; ADP-ribosylation factor family [PF00025.23, score=42.8]; 50S ribosome-binding GTPase [PF01926.25, score=19.7]} {Human: ENSG00000104388, RAB2A, RAB2A, member RAS oncogene family, [Score=348, Expect=1e-113]; ENSG00000129472, RAB2B, RAB2B, member RAS oncogene family, [Score=347, Expect=3e-113]} {Mouse: ENSMUSG00000047187, Rab2a, RAB2A, member RAS oncogene family, [Score=348, Expect=9e-114]; ENSMUSG00000022159, Rab2b, RAB2B, member RAS oncogene family, [Score=341, Expect=6e-111]} {Dmel: FBgn0014009, Rab2, [Score=345, Expect=2e-112]} {Celegans: WBGene00006833, unc-108, Rab-2, [Score=349, Expect=4e-114]} {Smed: dd_Smed_v6_1113_0_1, dd_Smed_v6_1113_0_1, [Score=362, Expect=3e-119]} {RNA1509_36943, RNA1509_58716} {RNA1310_1719.2, RNA1509_36943} {RNA1509_36943, RNA815_1051}

Mlig455_038500 {REF} {Length: 2295} {Pfam: Ras family [PF00071.24, score=155.5]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=79.9]; Lecithin retinol acyltransferase [PF04970.15, score=57.4]; ADP-ribosylation factor family [PF00025.23, score=19.5]} {Human: ENSG00000104388, RAB2A, RAB2A, member RAS oncogene family, [Score=260, Expect=3e-80]; ENSG00000129472, RAB2B, RAB2B, member RAS oncogene family, [Score=258, Expect=1e-79]} {Mouse: ENSMUSG00000047187, Rab2a, RAB2A, member RAS oncogene family, [Score=260, Expect=2e-80]; ENSMUSG00000022159, Rab2b, RAB2B, member RAS oncogene family, [Score=256, Expect=6e-79]} {Dmel: FBgn0014009, Rab2, [Score=254, Expect=1e-78]} {Celegans: WBGene00006833, unc-108, Rab-2, [Score=256, Expect=2e-79]} {Smed: dd_Smed_v6_1113_0_1, dd_Smed_v6_1113_0_1, [Score=261, Expect=4e-81]} {RNA1509_27474} {RNA1310_29729.1} {RNA815_10624.1}

Mlig455_052299 {REF} {Length: 3083} {Pfam: Ras family [PF00071.24, score=208.1]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=113.7]; ADP-ribosylation factor family [PF00025.23, score=48.1]; 50S ribosome-binding GTPase [PF01926.25, score=23.5]; RsgA GTPase [PF03193.18, score=21.2]; Elongation factor Tu GTP binding domain [PF00009.29, score=19.4]} {Human: ENSG00000129472, RAB2B, RAB2B, member RAS oncogene family, [RH, Score=366, Expect=7e-130]; ENSG00000104388, RAB2A, RAB2A, member RAS oncogene family, [RH, Score=365, Expect=8e-130]} {Mouse: ENSMUSG00000022159, Rab2b, RAB2B, member RAS oncogene family, [RH, Score=361, Expect=4e-128]} {Dmel: FBgn0014009, Rab2, [Score=363, Expect=3e-129]} {Celegans: WBGene00006833, unc-108, Rab-2, [Score=368, Expect=3e-131]} {Smed: dd_Smed_v6_1113_0_1, dd_Smed_v6_1113_0_1, [RH, Score=380, Expect=5e-136]} {RNA1509_20374, RNA1509_27474, RNA1509_50064} {RNA1310_32230, RNA1509_20374, RNA1509_27474, RNA1509_50064} {RNA1509_20374, RNA1509_27474, RNA1509_50064, RNA815_12751.1}
25. MligTC455_41400 3552 74 Mlig455_029570, Mlig455_046296, Mlig455_061526

Neo: -

Age: -

Region-specific R4: 2.185

Region-enriched R4: 1.659/0.00012

2.514 - - - 0.952 0.760 0.802

Mlig455_029570 {REF} {Length: 2138} {TRANSSPLICED} {RNA1509_21691} {RNA1310_10033} {RNA815_18948.1}

Mlig455_046296 {REF} {Length: 2214} {TRANSSPLICED} {RNA1509_28876, RNA1509_31568, RNA1509_35965, RNA1509_57314} {RNA1310_10033, RNA1509_28876, RNA1509_31568, RNA1509_57314} {RNA1509_28876, RNA1509_31568, RNA1509_57314, RNA815_18948.1}

Mlig455_061526 {REF} {Length: 2186} {TRANSSPLICED} {RNA1509_21691, RNA1509_35965} {RNA1310_10033, RNA1509_21691, RNA1509_35965} {RNA1509_21691, RNA1509_35965, RNA815_18948.1}
26. MligTC455_46914 423 8.82 Mlig455_060252

Neo: Irradiation

Age: -

NOTCH3 2.493 - 0.717 - 0.960 - 0.816 Mlig455_060252 {REF} {Length: 3099} {Pfam: EGF-like domain [PF00008.29, score=49.3]; Calcium-binding EGF domain [PF07645.17, score=39.7]; Human growth factor-like EGF [PF12661.9, score=29.8]; EGF domain [PF12947.9, score=25.8]; EGF-like domain [PF07974.15, score=23.7]} {Human: ENSG00000074181, NOTCH3, notch 3, [Score=86.3, Expect=7e-17]} {Mouse: ENSMUSG00000038146, Notch3, notch 3, [Score=82.4, Expect=7e-16]} {Dmel: FBgn0051665, wry, weary, [Score=95.5, Expect=3e-20]} {Celegans: WBGene00001609, glp-1, [Score=74.7, Expect=9e-14]} {Smed: dd_Smed_v6_6929_0_1, dd_Smed_v6_6929_0_1, [Score=115, Expect=1e-27]} {RNA1509_21381} {RNA1310_11756, RNA1509_21381} {RNA1509_21381, RNA815_17372.1}
27. MligTC455_49787 365 7.6 Mlig455_015283

Neo: Int S/G2/M

Age: -

Region-enriched R5: 1.843/0.00017

2.487 - 0.747 - 0.964 - 0.776 Mlig455_015283 {REF} {Length: 3599} {TRANSSPLICED} {Pfam: NMDA receptor-regulated gene protein 2 C-terminus [PF10505.11, score=48.3]} {RNA1509_32951, RNA1509_53417} {RNA1310_4961, RNA1509_53417} {RNA1509_53417, RNA815_3973}
28. MligTC455_22784 1148 23.93 Mlig455_002948

Neo: -

Age: Up-Down-Up

Region-enriched R4: 1.262/0.00560

ACSF2 2.485 0.815 - - 0.954 - 0.716 Mlig455_002948 {REF} {Length: 3655} {TRANSSPLICED} {Pfam: AMP-binding enzyme [PF00501.30, score=323.5]; AMP-binding enzyme C-terminal domain [PF13193.8, score=73.5]} {Human: ENSG00000167107, ACSF2, acyl-CoA synthetase family member 2, [Score=196, Expect=2e-54]} {Mouse: ENSMUSG00000076435, Acsf2, acyl-CoA synthetase family member 2, [Score=207, Expect=1e-58]} {Dmel: FBgn0027601, pdgy, pudgy, [Score=326, Expect=5e-104]} {Celegans: WBGene00008669, acs-14, Fatty Acid CoA Synthetase family, [Score=317, Expect=3e-101]} {Smed: dd_Smed_v6_10135_0_1, dd_Smed_v6_10135_0_1, [Score=363, Expect=5e-119]} {RNA1509_14977} {RNA1310_6662.1, RNA1509_14977} {RNA1509_14977, RNA815_3874}
29. MligTC455_38313 522 10.88 Mlig455_049035

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.871

DAB2IP 2.482 0.799 - - 0.969 - 0.714 Mlig455_049035 {REF} {Length: 5019} {Pfam: GTPase-activator protein for Ras-like GTPase [PF00616.21, score=23.7]} {Human: ENSG00000136848, DAB2IP, DAB2 interacting protein, [Score=135, Expect=5e-33]; ENSG00000075391, RASAL2, RAS protein activator like 2, [Score=133, Expect=4e-32]} {Mouse: ENSMUSG00000026883, Dab2ip, disabled 2 interacting protein, [Score=134, Expect=8e-33]; ENSMUSG00000070565, Rasal2, RAS protein activator like 2, [Score=133, Expect=3e-32]} {Dmel: FBgn0261570, CG42684, [Score=110, Expect=8e-25]} {Celegans: WBGene00001516, gap-2, Ras GTPase-activating protein gap-2, [Score=109, Expect=1e-24]} {Smed: dd_Smed_v6_3238_0_1, dd_Smed_v6_3238_0_1, [Score=87.4, Expect=7e-18]} {RNA1509_18843} {RNA1310_8785.1} {RNA815_30065}
30. MligTC455_21887 389 8.11 Mlig455_071132

Neo: -

Age: Up-Down-Down

2.473 - - - 0.975 0.709 0.789 Mlig455_071132 {REF} {Length: 2942} {RNA1509_37159, RNA1509_40169, RNA1509_59195} {RNA1310_39129, RNA1509_37159, RNA1509_40169, RNA1509_59195} {RNA1509_37159, RNA1509_40169, RNA1509_59195, RNA815_31168}
31. MligTC455_40163 637 13.28 Mlig455_020207

Neo: -

Age: -

MRPL49 2.458 0.775 - - 0.951 0.732 - Mlig455_020207 {REF} {Length: 1458} {TRANSSPLICED} {Pfam: Mitochondrial large subunit ribosomal protein (Img2) [PF05046.16, score=70.2]} {Human: ENSG00000149792, MRPL49, mitochondrial ribosomal protein L49, [RH, Score=87.0, Expect=4e-21]} {Mouse: ENSMUSG00000007338, Mrpl49, mitochondrial ribosomal protein L49, [RH, Score=96.3, Expect=1e-24]} {Dmel: FBgn0030433, mRpL49, mitochondrial ribosomal protein L49, [RH, Score=82.4, Expect=2e-19]} {Celegans: WBGene00011247, mrpl-49, Probable 39S ribosomal protein L49, mitochondrial, [RH, Score=72.8, Expect=7e-16]} {Smed: dd_Smed_v6_5783_1_1, dd_Smed_v6_5783_1_1, [RH, Score=104, Expect=5e-28]} {RNA1509_13816, RNA1509_23134, RNA1509_38178, RNA1509_46731} {RNA1310_20736, RNA1509_13816, RNA1509_23134, RNA1509_38178, RNA1509_46731} {RNA1509_13816, RNA1509_23134, RNA1509_38178, RNA1509_46731, RNA815_39575}
32. MligTC455_26386 624 13 Mlig455_020042

Neo: -

Age: logFC(26M/2M)=0.231

Region-enriched R5: 1.382/0.00337

2.455 0.796 - - 0.956 - 0.703 Mlig455_020042 {REF} {Length: 4207} {TRANSSPLICED} {Smed: dd_Smed_v6_3465_0_1, dd_Smed_v6_3465_0_1, [RH, Score=112, Expect=6e-26]} {RNA1509_13462, RNA1509_58720} {RNA1310_9257, RNA1509_13462, RNA1509_58720} {RNA1509_13462, RNA1509_58720, RNA815_5213}
33. MligTC455_48984 903 18.82 Mlig455_006597

Neo: -

Age: -

Region-enriched R5: 1.603/0.04044

HEXB 2.455 - 0.733 0.758 0.964 - - Mlig455_006597 {REF} {Length: 4049} {TRANSSPLICED} {Pfam: Glycosyl hydrolase family 20, catalytic domain [PF00728.24, score=280.8]; beta-acetyl hexosaminidase like [PF14845.8, score=64.9]; Glycosyl hydrolase family 20, domain 2 [PF02838.17, score=25.4]} {Human: ENSG00000049860, HEXB, hexosaminidase subunit beta, [Score=405, Expect=3e-131]; ENSG00000213614, HEXA, hexosaminidase subunit alpha, [Score=393, Expect=4e-127]} {Mouse: ENSMUSG00000021665, Hexb, hexosaminidase B, [Score=397, Expect=7e-129]; ENSMUSG00000025232, Hexa, hexosaminidase A, [Score=395, Expect=3e-128]} {Dmel: FBgn0045063, fdl, fused lobes, [RH, Score=214, Expect=4e-59]} {Celegans: WBGene00020509, hex-1, Beta-hexosaminidase A, [Score=313, Expect=9e-97]} {Smed: dd_Smed_v6_3964_0_1, dd_Smed_v6_3964_0_1, [RH, Score=477, Expect=9e-157]} {RNA1509_11107} {RNA1310_1997.1} {RNA815_5636}
34. MligTC455_54168 830 17.3 Mlig455_037740, Mlig455_037811

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.283

Region-enriched R5: 1.368/0.00226

CYP2A13, CYP2J2 2.455 - - 0.770 0.965 - 0.720

Mlig455_037740 {REF} {Length: 2544} {Pfam: Cytochrome P450 [PF00067.24, score=163.4]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=135, Expect=1e-35]; ENSG00000138115, CYP2C8, cytochrome P450 family 2 subfamily C member 8, [Score=132, Expect=2e-34]; ENSG00000138109, CYP2C9, cytochrome P450 family 2 subfamily C member 9, [Score=129, Expect=9e-33]} {Mouse: ENSMUSG00000074254, Cyp2a4, cytochrome P450, family 2, subfamily a, polypeptide 4, [Score=140, Expect=4e-37]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [Score=140, Expect=6e-37]; ENSMUSG00000005547, Cyp2a5, cytochrome P450, family 2, subfamily a, polypeptide 5, [Score=137, Expect=6e-36]; ENSMUSG00000060613, Cyp2c70, cytochrome P450, family 2, subfamily c, polypeptide 70, [Score=135, Expect=2e-35]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=134, Expect=6e-35]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [Score=134, Expect=2e-35]; ENSMUSG00000060407, Cyp2a12, cytochrome P450, family 2, subfamily a, polypeptide 12, [Score=133, Expect=1e-34]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=117, Expect=1e-28]} {Celegans: WBGene00021168, cyp-33C12, CYtochrome P450 family, [Score=138, Expect=6e-37]} {Smed: dd_Smed_v6_2351_0_4, dd_Smed_v6_2351_0_4, [Score=152, Expect=1e-41]} {RNA1509_35530} {RNA1310_9717} {RNA815_6000.2}

Mlig455_037811 {REF} {Length: 2453} {Pfam: Cytochrome P450 [PF00067.24, score=332.7]} {Human: ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [Score=240, Expect=5e-73]; ENSG00000138115, CYP2C8, cytochrome P450 family 2 subfamily C member 8, [Score=240, Expect=5e-73]; ENSG00000198077, CYP2A7, cytochrome P450 family 2 subfamily A member 7, [Score=239, Expect=2e-72]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [Score=239, Expect=1e-72]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [Score=237, Expect=8e-72]; ENSG00000138109, CYP2C9, cytochrome P450 family 2 subfamily C member 9, [Score=229, Expect=8e-69]; ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=228, Expect=3e-68]} {Mouse: ENSMUSG00000074254, Cyp2a4, cytochrome P450, family 2, subfamily a, polypeptide 4, [Score=246, Expect=2e-75]; ENSMUSG00000005547, Cyp2a5, cytochrome P450, family 2, subfamily a, polypeptide 5, [Score=242, Expect=9e-74]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [Score=239, Expect=1e-72]; ENSMUSG00000067231, Cyp2c65, cytochrome P450, family 2, subfamily c, polypeptide 65, [Score=236, Expect=1e-71]; ENSMUSG00000060407, Cyp2a12, cytochrome P450, family 2, subfamily a, polypeptide 12, [Score=236, Expect=1e-71]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=236, Expect=4e-71]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [Score=229, Expect=4e-69]} {Smed: dd_Smed_v6_2351_0_4, dd_Smed_v6_2351_0_4, [Score=285, Expect=1e-90]} {RNA1509_35530, RNA1509_57490, RNA1509_59085} {RNA1310_9717, RNA1509_35530, RNA1509_57490, RNA1509_59085} {RNA1509_35530, RNA1509_57490, RNA1509_59085, RNA815_6000.1}
35. MligTC455_26350 612 12.75 Mlig455_001446

Neo: -

Age: -

Region-enriched R5: 1.077/0.00379

NR1H3 2.442 - - - 0.965 0.772 0.705 Mlig455_001446 {REF} {Length: 3852} {TRANSSPLICED} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=76.5]} {Human: ENSG00000025434, NR1H3, nuclear receptor subfamily 1 group H member 3, [Score=132, Expect=5e-33]; ENSG00000144852, NR1I2, nuclear receptor subfamily 1 group I member 2, [Score=132, Expect=5e-33]} {Mouse: ENSMUSG00000022809, Nr1i2, nuclear receptor subfamily 1, group I, member 2, [Score=143, Expect=3e-37]} {Dmel: FBgn0000546, EcR, Ecdysone receptor, [Score=145, Expect=4e-37]} {Celegans: WBGene00000908, daf-12, Nuclear hormone receptor family member daf-12, [Score=117, Expect=2e-27]} {Smed: dd_Smed_v6_11714_0_1, dd_Smed_v6_11714_0_1, [Score=318, Expect=2e-103]} {RNA1509_19723, RNA1509_34225, RNA1509_43223, RNA1509_54792} {RNA1310_6855.1, RNA1509_19723, RNA1509_34225, RNA1509_43223, RNA1509_54792} {RNA1509_19723, RNA1509_34225, RNA1509_43223, RNA1509_54792, RNA815_9166}
36. MligTC455_36098 420 8.75 Mlig455_031103

Neo: -

Age: -

ACOT9 2.433 0.966 - - - 0.727 0.740 Mlig455_031103 {REF} {Length: 1642} {TRANSSPLICED} {Pfam: Thioesterase superfamily [PF03061.24, score=23.6]} {Human: ENSG00000123130, ACOT9, acyl-CoA thioesterase 9, [RH, Score=290, Expect=1e-93]} {Mouse: ENSMUSG00000025287, Acot9, acyl-CoA thioesterase 9, [RH, Score=285, Expect=1e-91]; ENSMUSG00000047565, Acot10, acyl-CoA thioesterase 10, [RH, Score=278, Expect=6e-89]} {Dmel: FBgn0039854, CG1635, [RH, Score=201, Expect=9e-60]} {Celegans: WBGene00019015, F57F4.1, [RH, Score=144, Expect=2e-38]} {RNA1509_28771} {RNA1310_18792} {RNA815_7625}
37. MligTC455_25047 135 2.82 Mlig455_041213

Neo: -

Age: -

RNF31 2.401 0.951 - - - 0.704 0.746 Mlig455_041213 {REF} {Length: 3533} {TRANSSPLICED} {Pfam: IBR domain, a half RING-finger domain [PF01485.23, score=39.2]; E3 Ubiquitin Ligase RBR C-terminal domain [PF18091.3, score=27.3]; Domain of unknown function (DUF4573) [PF15140.8, score=21.0]} {Human: ENSG00000285152, RNF31, ring finger protein 31, [Score=188, Expect=2e-49]; ENSG00000092098, RNF31, ring finger protein 31, [Score=188, Expect=2e-49]; ENSG00000284845, AL136295.10, novel transcript, [Score=185, Expect=3e-50]; ENSG00000259529, AL136295.5, novel transcript, [Score=185, Expect=3e-50]} {Mouse: ENSMUSG00000047098, Rnf31, ring finger protein 31, [Score=184, Expect=3e-48]} {Dmel: FBgn0031857, LUBEL, Linear Ubiquitin E3 ligase, [Score=171, Expect=7e-44]} {Smed: dd_Smed_v6_4074_0_1, dd_Smed_v6_4074_0_1, [RH, Score=134, Expect=1e-32]} {RNA1509_18940} {RNA1310_17723.1} {RNA815_23151}
38. MligTC455_41572 746 15.54 Mlig455_030760

Neo: Int S/G2/M

Age: Down-Up-Down

Region-enriched R5: 1.596/0.00078

2.394 - - 0.704 0.970 - 0.720 Mlig455_030760 {REF} {Length: 2018} {TRANSSPLICED} {Pfam: DNA polymerase subunit Cdc27 [PF09507.12, score=38.5]} {RNA1509_21656, RNA1509_38904, RNA1509_41902} {RNA1310_13885, RNA1509_21656, RNA1509_38904, RNA1509_41902} {RNA1509_21656, RNA1509_38904, RNA1509_41902, RNA815_5435.1}
39. MligTC455_43329 235 4.9 Mlig455_007154

Neo: -

Age: -

Region-enriched R2: 3.268/0.02528
Region-enriched R5: 2.289/0.03532

SMURF2 1.908 0.954 - - 0.954 - - Mlig455_007154 {REF} {Length: 4687} {Pfam: HECT-domain (ubiquitin-transferase) [PF00632.27, score=303.1]; WW domain [PF00397.28, score=64.2]} {Human: ENSG00000108854, SMURF2, SMAD specific E3 ubiquitin protein ligase 2, [RH, Score=636, Expect=0.0]} {Mouse: ENSMUSG00000018363, Smurf2, SMAD specific E3 ubiquitin protein ligase 2, [RH, Score=637, Expect=0.0]} {Dmel: FBgn0259174, Nedd4, [Score=409, Expect=4e-133]} {Celegans: WBGene00022358, Y92H12A.2, E3 ubiquitin-protein ligase, [Score=400, Expect=2e-133]} {Smed: dd_Smed_v6_7322_0_1, dd_Smed_v6_7322_0_1, [Score=398, Expect=2e-128]} {RNA1509_42014} {RNA1310_6371} {RNA815_17584}
40. MligTC455_29193 967 20.15 Mlig455_018315, Mlig455_061014, Mlig455_067207

Neo: -

Age: Down-Down-Up

1.896 0.930 - - 0.966 - -

Mlig455_018315 {REF} {Length: 2676} {TRANSSPLICED} {RNA1509_52931} {RNA1310_28021} {RNA815_28552}

Mlig455_061014 {REF} {Length: 2001} {RNA1310_29654.1} {RNA815_17301.1}

Mlig455_067207 {REF} {Length: 584} {TRANSSPLICED} {RNA1310_29654.1} {RNA815_17301.1}
41. MligTC455_19849 803 16.74 Mlig455_001790

Neo: -

Age: -

1.89 - - - 0.970 - 0.920 Mlig455_001790 {REF} {Length: 3366} {TRANSSPLICED} {Pfam: Peptidase family M3 [PF01432.22, score=55.7]} {RNA1509_4620} {RNA1310_8121, RNA1509_4620} {RNA1509_4620, RNA815_2560.1}
42. MligTC455_44341 241 5.03 Mlig455_004553

Neo: -

Age: -

SENP8 1.882 0.909 - - 0.973 - - Mlig455_004553 {REF} {Length: 1090} {Pfam: Ulp1 protease family, C-terminal catalytic domain [PF02902.21, score=31.5]} {Human: ENSG00000166192, SENP8, SUMO peptidase family member, NEDD8 specific, [Score=50.1, Expect=3e-07]} {Mouse: ENSMUSG00000051705, Senp8, SUMO/sentrin specific peptidase 8, [Score=47.4, Expect=2e-06]} {RNA1509_41235} {RNA1310_35410} {RNA815_32992}
43. MligTC455_26666 497 10.35 Mlig455_014576

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.303

CNBD2 1.875 0.915 - - 0.960 - - Mlig455_014576 {REF} {Length: 3147} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=74.1]} {Human: ENSG00000149646, CNBD2, cyclic nucleotide binding domain containing 2, [RH, Score=97.8, Expect=2e-20]} {Mouse: ENSMUSG00000038085, Cnbd2, cyclic nucleotide binding domain containing 2, [RH, Score=86.3, Expect=3e-17]} {Dmel: FBgn0259243, Pka-R1, Protein kinase, cAMP-dependent, regulatory subunit type 1, [Score=58.2, Expect=9e-09]} {Celegans: WBGene00002190, kin-2, cAMP-dependent protein kinase regulatory subunit, [Score=62.0, Expect=5e-10]} {Smed: dd_Smed_v6_15589_0_1, dd_Smed_v6_15589_0_1, [RH, Score=451, Expect=2e-148]} {RNA1509_14495, RNA1509_43806} {RNA1310_6298, RNA1509_43806} {RNA1509_43806, RNA815_2010}
44. MligTC455_19737 936 19.49 Mlig455_001707

Neo: -

Age: -

1.865 0.956 - - 0.909 - - Mlig455_001707 {REF} {Length: 1748} {TRANSSPLICED} {Pfam: Mucin-like [PF16058.7, score=34.2]} {Smed: dd_Smed_v6_3936_0_1, dd_Smed_v6_3936_0_1, [Score=102, Expect=4e-24]} {RNA1509_50300} {RNA1310_14121} {RNA815_5699.1}
45. MligTC455_44648 177 3.69 Mlig455_013655

Neo: -

Age: -

1.863 0.908 - - 0.955 - - Mlig455_013655 {REF} {Length: 2045} {Pfam: Protein kinase domain [PF00069.27, score=24.6]} {RNA1509_54731} {RNA1310_1875.2} {RNA815_820}
46. MligTC455_20119 598 12.46 Mlig455_004412

Neo: -

Age: Up-Down-Up

Region-enriched R5: 1.039/0.00796

MPG 1.857 - - - 0.975 - 0.882 Mlig455_004412 {REF} {Length: 2516} {Pfam: Methylpurine-DNA glycosylase (MPG) [PF02245.18, score=196.0]} {Human: ENSG00000103152, MPG, N-methylpurine DNA glycosylase, [RH, Score=170, Expect=8e-50]} {Mouse: ENSMUSG00000020287, Mpg, N-methylpurine-DNA glycosylase, [RH, Score=180, Expect=2e-53]} {Dmel: FBgn0003374, Sgs4, Salivary gland secretion 4, [Score=51.2, Expect=6e-07]} {Smed: dd_Smed_v6_13854_0_1, dd_Smed_v6_13854_0_1, [RH, Score=144, Expect=5e-41]} {RNA1509_36647} {RNA1310_24696.1} {RNA815_12448.1}
47. MligTC455_20120 961 20.02 Mlig455_037234, Mlig455_037245

Neo: -

Age: -

Region-enriched R4: 1.425/0.00193
Region-enriched R5: 1.319/0.00012

UPRT 1.855 - - - 0.983 - 0.872

Mlig455_037234 {REF} {Length: 2229} {TRANSSPLICED} {Pfam: Methylpurine-DNA glycosylase (MPG) [PF02245.18, score=194.3]; Uracil phosphoribosyltransferase [PF14681.8, score=129.2]} {Human: ENSG00000094841, UPRT, uracil phosphoribosyltransferase homolog, [Score=206, Expect=1e-60]} {Mouse: ENSMUSG00000073016, Uprt, uracil phosphoribosyltransferase, [Score=210, Expect=2e-62]} {Dmel: FBgn0035639, kri, krishah, [Score=189, Expect=2e-55]} {Celegans: WBGene00008131, C47B2.2, [Score=185, Expect=3e-54]} {Smed: dd_Smed_v6_6546_0_1, dd_Smed_v6_6546_0_1, [Score=202, Expect=1e-60]} {RNA1509_36647} {RNA1310_24696.1} {RNA815_12448.1}

Mlig455_037245 {REF} {Length: 2190} {TRANSSPLICED} {Pfam: Methylpurine-DNA glycosylase (MPG) [PF02245.18, score=194.9]; Uracil phosphoribosyltransferase [PF14681.8, score=129.2]} {Human: ENSG00000094841, UPRT, uracil phosphoribosyltransferase homolog, [Score=205, Expect=2e-60]} {Mouse: ENSMUSG00000073016, Uprt, uracil phosphoribosyltransferase, [Score=209, Expect=2e-62]} {Dmel: FBgn0035639, kri, krishah, [Score=189, Expect=2e-55]} {Celegans: WBGene00008131, C47B2.2, [Score=185, Expect=2e-54]} {Smed: dd_Smed_v6_6546_0_1, dd_Smed_v6_6546_0_1, [Score=201, Expect=1e-60]} {RNA1509_36647} {RNA1310_24696.1, RNA1509_36647} {RNA1509_36647, RNA815_12448.1}
48. MligTC455_50262 320 6.67 Mlig455_019038

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.470

TARBP2 1.848 0.975 - - - - 0.873 Mlig455_019038 {REF} {Length: 1661} {TRANSSPLICED} {Pfam: Double-stranded RNA binding motif [PF00035.28, score=62.0]; Staufen C-terminal domain [PF16482.7, score=26.1]} {Human: ENSG00000139546, TARBP2, TARBP2, RISC loading complex RNA binding subunit, [RH, Score=62.0, Expect=2e-11]} {Mouse: ENSMUSG00000023051, Tarbp2, TARBP2, RISC loading complex RNA binding subunit, [Score=81.6, Expect=1e-17]} {Dmel: FBgn0032515, loqs, loquacious, [RH, Score=121, Expect=2e-30]} {Smed: dd_Smed_v6_9213_0_1, dd_Smed_v6_9213_0_1, [RH, Score=157, Expect=1e-44]} {RNA1509_37226} {RNA1310_1441.1} {RNA815_48096}
49. MligTC455_26643 312 6.5 Mlig455_028106

Neo: -

Age: Down-Up-Up

Region-enriched R5: 2.240/0.02123

TUBGCP2 1.846 - - - 0.966 - 0.880 Mlig455_028106 {REF} {Length: 2771} {TRANSSPLICED} {Pfam: Gamma tubulin complex component C-terminal [PF04130.15, score=239.2]; Gamma tubulin complex component N-terminal [PF17681.3, score=207.5]} {Human: ENSG00000130640, TUBGCP2, tubulin gamma complex associated protein 2, [RH, Score=574, Expect=0.0]} {Mouse: ENSMUSG00000025474, Tubgcp2, tubulin, gamma complex associated protein 2, [RH, Score=565, Expect=0.0]} {Dmel: FBgn0026430, Grip84, Gamma-tubulin ring protein 84, [RH, Score=346, Expect=1e-105]} {Smed: dd_Smed_v6_7469_0_1, dd_Smed_v6_7469_0_1, [RH, Score=365, Expect=6e-114]} {RNA1509_10994} {RNA1310_6326} {RNA815_15698.1}
50. MligTC455_33167 416 8.66 Mlig455_063071

Neo: -

Age: -

Region-enriched R5: 1.683/0.00006

SARM1 1.846 - - - 0.970 - 0.876 Mlig455_063071 {REF} {Length: 4307} {Pfam: TIR domain [PF13676.8, score=65.0]} {Human: ENSG00000004139, SARM1, sterile alpha and TIR motif containing 1, [Score=54.7, Expect=3e-07]} {Mouse: ENSMUSG00000050132, Sarm1, sterile alpha and HEAT/Armadillo motif containing 1, [Score=50.8, Expect=8e-06]} {RNA1509_29716, RNA1509_30913} {RNA1310_4887.1, RNA1509_29716, RNA1509_30913} {RNA1509_29716, RNA1509_30913, RNA815_10844}
51. MligTC455_41761 655 13.65 Mlig455_020225

Neo: Irradiation

Age: -

Region-enriched R5: 1.227/0.00118

PTPRZ1 1.846 0.884 - - 0.962 - - Mlig455_020225 {REF} {Length: 5464} {TRANSSPLICED} {Pfam: Protein-tyrosine phosphatase [PF00102.29, score=409.3]; Fibronectin type III domain [PF00041.23, score=83.6]; Dual specificity phosphatase, catalytic domain [PF00782.22, score=24.2]} {Human: ENSG00000106278, PTPRZ1, protein tyrosine phosphatase, receptor type Z1, [RH, Score=492, Expect=4e-149]; ENSG00000144724, PTPRG, protein tyrosine phosphatase, receptor type G, [RH, Score=492, Expect=4e-149]} {Mouse: ENSMUSG00000068748, Ptprz1, protein tyrosine phosphatase, receptor type Z, polypeptide 1, [RH, Score=491, Expect=6e-145]; ENSMUSG00000021745, Ptprg, protein tyrosine phosphatase, receptor type, G, [RH, Score=485, Expect=1e-146]} {Dmel: FBgn0004369, Ptp99A, Protein tyrosine phosphatase 99A, [RH, Score=469, Expect=9e-143]} {Celegans: WBGene00004215, ptp-3, Tyrosine-protein phosphatase Lar-like, [Score=348, Expect=9e-101]} {Smed: dd_Smed_v6_6997_0_1, dd_Smed_v6_6997_0_1, [RH, Score=564, Expect=9e-177]} {RNA1509_4639} {RNA1310_810} {RNA815_3651}
52. MligTC455_43712 875 18.23 Mlig455_009281, Mlig455_037026

Neo: -

Age: -

Region-enriched R5: 1.586/0.00003

EXOC5 1.841 - - - 0.965 - 0.876

Mlig455_009281 {REF} {Length: 3264} {TRANSSPLICED} {Pfam: Exocyst complex component Sec10 [PF07393.13, score=300.0]} {Human: ENSG00000070367, EXOC5, exocyst complex component 5, [RH, Score=339, Expect=1e-105]} {Mouse: ENSMUSG00000061244, Exoc5, exocyst complex component 5, [RH, Score=338, Expect=2e-105]} {Dmel: FBgn0266673, Sec10, Secretory 10, [RH, Score=284, Expect=3e-85]} {Celegans: WBGene00016376, sec-10, Exocyst complex component 5, [RH, Score=241, Expect=2e-69]} {Smed: dd_Smed_v6_7878_0_1, dd_Smed_v6_7878_0_1, [RH, Score=142, Expect=1e-36]} {RNA1509_9218} {RNA1310_7681} {RNA815_1816}

Mlig455_037026 {REF} {Length: 3353} {TRANSSPLICED} {Pfam: Exocyst complex component Sec10 [PF07393.13, score=300.0]} {Human: ENSG00000070367, EXOC5, exocyst complex component 5, [RH, Score=339, Expect=1e-105]} {Mouse: ENSMUSG00000061244, Exoc5, exocyst complex component 5, [RH, Score=338, Expect=2e-105]} {Dmel: FBgn0266673, Sec10, Secretory 10, [RH, Score=284, Expect=3e-85]} {Celegans: WBGene00016376, sec-10, Exocyst complex component 5, [RH, Score=241, Expect=2e-69]} {Smed: dd_Smed_v6_7878_0_1, dd_Smed_v6_7878_0_1, [RH, Score=142, Expect=1e-36]} {RNA1509_9218} {RNA1310_7681, RNA1509_9218} {RNA1509_9218, RNA815_1816}
53. MligTC455_47478 835 17.4 Mlig455_001127, Mlig455_042054

Neo: -

Age: -

SLC39A1 1.84 - - - 0.954 - 0.886

Mlig455_001127 {REF} {Length: 3754} {TRANSSPLICED} {Pfam: ZIP Zinc transporter [PF02535.24, score=189.7]} {Human: ENSG00000143570, SLC39A1, solute carrier family 39 member 1, [RH, Score=94.4, Expect=8e-21]} {Mouse: ENSMUSG00000052310, Slc39a1, solute carrier family 39 (zinc transporter), member 1, [RH, Score=97.1, Expect=7e-22]} {Dmel: FBgn0033096, Zip42C.1, Zinc/iron regulated transporter-related protein 42C.1, [RH, Score=88.6, Expect=5e-19]} {Celegans: WBGene00009286, zipt-1, Zrt (ZRT), Irt-(IRT-) like Protein Transporter, [RH, Score=100, Expect=3e-23]} {Smed: dd_Smed_v6_6246_0_1, dd_Smed_v6_6246_0_1, [RH, Score=119, Expect=1e-29]} {RNA1509_33551, RNA1509_48677} {RNA1310_9586, RNA1509_33551, RNA1509_48677} {RNA1509_33551, RNA1509_48677, RNA815_8641}

Mlig455_042054 {REF} {Length: 3412} {TRANSSPLICED} {Pfam: ZIP Zinc transporter [PF02535.24, score=190.3]} {Human: ENSG00000143570, SLC39A1, solute carrier family 39 member 1, [RH, Score=94.0, Expect=2e-20]} {Mouse: ENSMUSG00000052310, Slc39a1, solute carrier family 39 (zinc transporter), member 1, [RH, Score=96.7, Expect=1e-21]} {Dmel: FBgn0033096, Zip42C.1, Zinc/iron regulated transporter-related protein 42C.1, [RH, Score=89.4, Expect=5e-19]} {Celegans: WBGene00009286, zipt-1, Zrt (ZRT), Irt-(IRT-) like Protein Transporter, [RH, Score=100, Expect=5e-23]} {Smed: dd_Smed_v6_6246_0_1, dd_Smed_v6_6246_0_1, [RH, Score=119, Expect=2e-29]} {RNA1509_47585} {RNA1310_12629} {RNA815_8641}
54. MligTC455_22792 813 16.94 Mlig455_006911

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.573

PPP1R10 1.838 0.871 - - 0.967 - - Mlig455_006911 {REF} {Length: 4431} {TRANSSPLICED} {tRNA: Val(CAC),pseudo, score=34.5} {Pfam: TFIIS helical bundle-like domain [PF08711.13, score=20.9]; Negative regulator of genetic competence (MecA) [PF05389.14, score=18.7]} {Human: ENSG00000204569, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000230995, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000238104, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000235291, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000206489, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000227804, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000231737, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]} {Mouse: ENSMUSG00000039220, Ppp1r10, protein phosphatase 1, regulatory subunit 10, [RH, Score=95.1, Expect=2e-19]} {Dmel: FBgn0053526, PNUTS, [RH, Score=87.4, Expect=4e-17]} {Smed: dd_Smed_v6_3726_0_1, dd_Smed_v6_3726_0_1, [Score=93.2, Expect=2e-19]} {RNA1509_35861, RNA1509_3759, RNA1509_41300} {RNA1310_6625, RNA1509_35861, RNA1509_41300} {RNA1509_35861, RNA1509_41300, RNA815_5489}
55. MligTC455_17963 584 12.16 Mlig455_049086

Neo: -

Age: Down-Up-Down

Region-enriched R4: 1.446/0.04930

ABCG2 1.837 0.883 - - 0.954 - - Mlig455_049086 {REF} {Length: 3159} {Pfam: ABC-2 type transporter [PF01061.26, score=135.0]; ABC transporter [PF00005.29, score=78.2]; ABC-2 type transporter [PF19055.2, score=69.9]; AAA domain, putative AbiEii toxin, Type IV TA system [PF13304.8, score=34.8]; RecF/RecN/SMC N terminal domain [PF02463.21, score=26.0]; AAA domain [PF13476.8, score=20.8]; ABC-2 family transporter protein [PF12698.9, score=19.8]} {Human: ENSG00000118777, ABCG2, ATP binding cassette subfamily G member 2 (Junior blood group), [RH, Score=595, Expect=0.0]} {Mouse: ENSMUSG00000029802, Abcg2, ATP binding cassette subfamily G member 2 (Junior blood group), [RH, Score=583, Expect=0.0]} {Dmel: FBgn0003996, w, white, [RH, Score=284, Expect=4e-86]} {Celegans: WBGene00012925, wht-8, WHiTe (Drosophila) related ABC transporter, [RH, Score=262, Expect=8e-79]} {Smed: dd_Smed_v6_4225_0_1, dd_Smed_v6_4225_0_1, [Score=553, Expect=0.0]} {RNA1509_28179, RNA1509_9773} {RNA1310_7804.1, RNA1509_28179, RNA1509_9773} {RNA1509_28179, RNA1509_9773, RNA815_3051}
56. MligTC455_43514 599 12.48 Mlig455_008579

Neo: -

Age: -

OSBPL9 1.837 - - - 0.965 - 0.872 Mlig455_008579 {REF} {Length: 4182} {Pfam: Oxysterol-binding protein [PF01237.20, score=252.0]; PH domain [PF00169.31, score=48.5]; Pleckstrin homology domain [PF15409.8, score=30.7]; Protein of unknown function (DUF2722) [PF10846.10, score=20.4]; Pleckstrin homology domain [PF15413.8, score=19.2]} {Human: ENSG00000117859, OSBPL9, oxysterol binding protein like 9, [RH, Score=634, Expect=0.0]} {Mouse: ENSMUSG00000028559, Osbpl9, oxysterol binding protein-like 9, [RH, Score=642, Expect=0.0]} {Dmel: FBgn0033463, CG1513, [RH, Score=615, Expect=0.0]} {Celegans: WBGene00016331, obr-4, Oxysterol-binding protein, [RH, Score=458, Expect=2e-150]} {Smed: dd_Smed_v6_5947_0_1, dd_Smed_v6_5947_0_1, [RH, Score=602, Expect=0.0]} {RNA1509_43844, RNA1509_8406} {RNA1310_2180.1, RNA1509_43844, RNA1509_8406} {RNA1509_43844, RNA1509_8406, RNA815_7482.1}
57. MligTC455_46747 352 7.32 Mlig455_040380

Neo: -

Age: Up-Down-Up

ANKRD11 1.832 - - - 0.965 - 0.867 Mlig455_040380 {REF} {Length: 5078} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=63.8]; Ankyrin repeats (many copies) [PF13637.8, score=63.7]; Ankyrin repeats (many copies) [PF13857.8, score=62.2]; Ankyrin repeat [PF00023.32, score=53.6]; Ankyrin repeat [PF13606.8, score=43.7]} {Human: ENSG00000167522, ANKRD11, ankyrin repeat domain 11, [RH, Score=134, Expect=1e-30]; ENSG00000101745, ANKRD12, ankyrin repeat domain 12, [RH, Score=128, Expect=5e-29]} {Mouse: ENSMUSG00000035569, Ankrd11, ankyrin repeat domain 11, [RH, Score=134, Expect=4e-31]; ENSMUSG00000034647, Ankrd12, ankyrin repeat domain 12, [RH, Score=129, Expect=2e-29]} {Dmel: FBgn0036305, CG10984, [Score=104, Expect=1e-22]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=91.3, Expect=5e-18]} {Smed: dd_Smed_v6_9297_0_1, dd_Smed_v6_9297_0_1, [Score=152, Expect=2e-37]} {RNA1509_17750} {RNA1310_3406} {RNA815_33283}
58. MligTC455_52115 440 9.16 Mlig455_036485

Neo: -

Age: Down-Up-Up

SDE2 1.831 - - - 0.975 - 0.856 Mlig455_036485 {REF} {Length: 1485} {TRANSSPLICED} {Pfam: Silencing defective 2 N-terminal ubiquitin domain [PF13019.8, score=79.0]; Replication stress response SDE2 C-terminal [PF13297.8, score=71.6]; Cornifin (SPRR) family [PF02389.17, score=26.6]} {Human: ENSG00000143751, SDE2, SDE2 telomere maintenance homolog, [RH, Score=111, Expect=2e-26]} {Mouse: ENSMUSG00000038806, Sde2, SDE2 telomere maintenance homolog (S. pombe), [RH, Score=158, Expect=1e-43]} {Dmel: FBgn0043455, CG5986, [RH, Score=84.7, Expect=1e-18]} {Celegans: WBGene00009996, F53F4.14, [RH, Score=80.1, Expect=5e-16]} {Smed: dd_Smed_v6_5448_0_1, dd_Smed_v6_5448_0_1, [RH, Score=131, Expect=7e-35]} {RNA1509_43561} {RNA1310_32891} {RNA815_15881}
59. MligTC455_19505 530 11.03 Mlig455_065098

Neo: -

Age: -

ULK2 1.824 - - - 0.974 - 0.850 Mlig455_065098 {REF} {Length: 4075} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=215.2]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=156.5]; Domain of unknown function (DUF3543) [PF12063.10, score=40.8]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=28.3]; RIO1 family [PF01163.24, score=21.2]; Kinase-like [PF14531.8, score=17.9]} {Human: ENSG00000083290, ULK2, unc-51 like autophagy activating kinase 2, [RH, Score=344, Expect=5e-104]; ENSG00000177169, ULK1, unc-51 like autophagy activating kinase 1, [RH, Score=333, Expect=1e-99]} {Mouse: ENSMUSG00000004798, Ulk2, unc-51 like kinase 2, [RH, Score=340, Expect=1e-102]; ENSMUSG00000029512, Ulk1, unc-51 like kinase 1, [RH, Score=331, Expect=4e-99]} {Dmel: FBgn0260945, Atg1, Autophagy-related 1, [RH, Score=360, Expect=8e-112]} {Celegans: WBGene00006786, unc-51, Serine/threonine-protein kinase unc-51, [RH, Score=351, Expect=1e-108]} {Smed: dd_Smed_v6_10237_0_1, dd_Smed_v6_10237_0_1, [RH, Score=276, Expect=2e-86]} {RNA1509_51818, RNA1509_9723} {RNA1310_2515, RNA1509_51818} {RNA1509_51818, RNA815_10960.1}
60. MligTC455_20650 1130 23.53 Mlig455_026784

Neo: Int S/G2/M

Age: -

EARS2 1.819 0.958 - - - 0.861 - Mlig455_026784 {REF} {Length: 1927} {TRANSSPLICED} {Pfam: tRNA synthetases class I (E and Q), catalytic domain [PF00749.23, score=206.1]; Anticodon binding domain [PF19269.1, score=25.8]} {Human: ENSG00000103356, EARS2, glutamyl-tRNA synthetase 2, mitochondrial, [RH, Score=235, Expect=6e-70]} {Mouse: ENSMUSG00000030871, Ears2, glutamyl-tRNA synthetase 2, mitochondrial, [RH, Score=240, Expect=7e-72]} {Dmel: FBgn0036629, GluRS-m, Glutamyl-tRNA synthetase, mitochondrial, [RH, Score=227, Expect=3e-67]} {Celegans: WBGene00001338, ears-2, Glutamyl(E) Amino-acyl tRNA Synthetase, [RH, Score=215, Expect=4e-63]} {Smed: dd_Smed_v6_14303_0_1, dd_Smed_v6_14303_0_1, [RH, Score=232, Expect=2e-69]} {RNA1509_15646} {RNA1310_14615} {RNA815_5502}
61. MligTC455_20651 1132 23.57 Mlig455_051798

Neo: -

Age: -

EARS2 1.818 0.958 - - - 0.860 - Mlig455_051798 {REF} {Length: 2550} {TRANSSPLICED} {Pfam: tRNA synthetases class I (E and Q), catalytic domain [PF00749.23, score=204.3]; Ubiquitin-conjugating enzyme [PF00179.28, score=120.1]; Anticodon binding domain [PF19269.1, score=24.8]} {Human: ENSG00000103356, EARS2, glutamyl-tRNA synthetase 2, mitochondrial, [RH, Score=235, Expect=4e-68]} {Mouse: ENSMUSG00000030871, Ears2, glutamyl-tRNA synthetase 2, mitochondrial, [RH, Score=239, Expect=6e-70]} {Dmel: FBgn0036629, GluRS-m, Glutamyl-tRNA synthetase, mitochondrial, [RH, Score=227, Expect=1e-65]} {Celegans: WBGene00001338, ears-2, Glutamyl(E) Amino-acyl tRNA Synthetase, [RH, Score=214, Expect=4e-61]} {Smed: dd_Smed_v6_14303_0_1, dd_Smed_v6_14303_0_1, [RH, Score=231, Expect=2e-67]} {RNA1509_15646} {RNA1310_14615} {RNA815_5502}
62. MligTC455_39844 505 10.53 Mlig455_031945

Neo: Germline

Age: -

Region-enriched R5: 1.376/0.00458

1.818 - - - 0.966 0.852 - Mlig455_031945 {REF} {Length: 2587} {TRANSSPLICED} {Smed: dd_Smed_v6_11504_0_1, dd_Smed_v6_11504_0_1, [RH, Score=170, Expect=2e-48]} {RNA1509_35608, RNA1509_38226} {RNA1310_9352.1, RNA1509_35608} {RNA1509_35608, RNA815_18353}
63. MligTC455_53249 690 14.38 Mlig455_027272, Mlig455_027319

Neo: -

Age: -

Region-enriched R5: 1.274/0.02479

WBP4 1.816 - - - 0.960 - 0.856

Mlig455_027272 {REF} {Length: 1151} {TRANSSPLICED} {Pfam: WW domain [PF00397.28, score=42.3]; U1 zinc finger [PF06220.14, score=41.5]} {Human: ENSG00000120688, WBP4, WW domain binding protein 4, [Score=83.6, Expect=1e-17]} {Mouse: ENSMUSG00000022023, Wbp4, WW domain binding protein 4, [Score=88.6, Expect=1e-19]} {Dmel: FBgn0031287, CG4291, [RH, Score=91.3, Expect=5e-21]} {Smed: dd_Smed_v6_10030_0_6, dd_Smed_v6_10030_0_6, [RH, Score=87.4, Expect=1e-20]} {RNA1509_46002} {RNA1310_29789} {RNA815_12245}

Mlig455_027319 {REF} {Length: 1127} {TRANSSPLICED} {Pfam: WW domain [PF00397.28, score=42.3]; U1 zinc finger [PF06220.14, score=41.5]} {Human: ENSG00000120688, WBP4, WW domain binding protein 4, [Score=81.6, Expect=5e-17]} {Mouse: ENSMUSG00000022023, Wbp4, WW domain binding protein 4, [Score=88.2, Expect=1e-19]} {Dmel: FBgn0031287, CG4291, [RH, Score=91.3, Expect=7e-21]} {Smed: dd_Smed_v6_10030_0_6, dd_Smed_v6_10030_0_6, [RH, Score=87.4, Expect=1e-20]} {RNA1509_46002} {RNA1310_29789} {RNA815_12245}
64. MligTC455_17085 220 4.57 Mlig455_010614

Neo: -

Age: -

Region-enriched R5: 2.140/0.00793

SHOC2 1.814 - - - 0.954 - 0.860 Mlig455_010614 {REF} {Length: 7396} {TRANSSPLICED} {Pfam: Leucine rich repeat [PF13855.8, score=170.1]; Leucine Rich repeats (2 copies) [PF12799.9, score=106.5]; Carboxypeptidase regulatory-like domain [PF13620.8, score=96.7]; Prealbumin-like fold domain [PF17802.3, score=44.0]; Protein of unknown function (DUF2012) [PF09430.12, score=43.8]; SdrD B-like domain [PF17210.5, score=39.2]; CarboxypepD_reg-like domain [PF13715.8, score=27.4]; Protein of unknown function (DUF1416) [PF07210.14, score=21.7]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=20.8]; Leucine-rich repeat [PF14580.8, score=19.9]} {Human: ENSG00000108061, SHOC2, SHOC2, leucine rich repeat scaffold protein, [RH, Score=567, Expect=0.0]} {Mouse: ENSMUSG00000024976, Shoc2, Shoc2, leucine rich repeat scaffold protein, [RH, Score=562, Expect=0.0]} {Dmel: FBgn0038504, Sur-8, [RH, Score=564, Expect=0.0]} {Celegans: WBGene00004929, soc-2, Leucine-rich repeat protein soc-2, [RH, Score=506, Expect=3e-163]} {Smed: dd_Smed_v6_1909_0_1, dd_Smed_v6_1909_0_1, [RH, Score=663, Expect=0.0]} {RNA1509_3897} {RNA1310_2809.1} {RNA815_7195}
65. MligTC455_23399 761 15.85 Mlig455_009081

Neo: -

Age: -

NGLY1 1.808 - - - 0.956 - 0.852 Mlig455_009081 {REF} {Length: 4231} {TRANSSPLICED} {Pfam: PNGase C-terminal domain, mannose-binding module PAW [PF04721.19, score=208.6]; PUB domain [PF09409.12, score=60.3]; Rad4 transglutaminase-like domain [PF03835.17, score=47.0]; Transglutaminase-like superfamily [PF01841.21, score=45.1]; Thioredoxin [PF00085.22, score=44.8]} {Human: ENSG00000151092, NGLY1, N-glycanase 1, [RH, Score=396, Expect=4e-125]} {Mouse: ENSMUSG00000021785, Ngly1, N-glycanase 1, [RH, Score=412, Expect=2e-131]} {Dmel: FBgn0033050, Pngl, PNGase-like, [RH, Score=309, Expect=8e-93]} {Celegans: WBGene00010160, png-1, Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase, [RH, Score=260, Expect=2e-75]} {Smed: dd_Smed_v6_5705_0_1, dd_Smed_v6_5705_0_1, [RH, Score=290, Expect=1e-84]} {RNA1509_9974} {RNA1310_3958, RNA1509_9974} {RNA1509_9974, RNA815_834.1}
66. MligTC455_39377 2992 62.33 Mlig455_046114, Mlig455_046209

Neo: -

Age: logFC(26M/2M)=0.255

FUCA2 1.807 - - - 0.980 - 0.827

Mlig455_046114 {REF} {Length: 2446} {TRANSSPLICED} {Pfam: Alpha-L-fucosidase [PF01120.19, score=415.7]; Alpha-L-fucosidase C-terminal domain [PF16757.7, score=71.4]} {Human: ENSG00000001036, FUCA2, alpha-L-fucosidase 2, [RH, Score=542, Expect=0.0]; ENSG00000179163, FUCA1, alpha-L-fucosidase 1, [RH, Score=520, Expect=0.0]} {Mouse: ENSMUSG00000019810, Fuca2, fucosidase, alpha-L- 2, plasma, [RH, Score=535, Expect=0.0]; ENSMUSG00000028673, Fuca1, fucosidase, alpha-L- 1, tissue, [RH, Score=517, Expect=0.0]} {Dmel: FBgn0285958, Fuca, alpha-L-fucosidase, [RH, Score=465, Expect=3e-161]} {Celegans: WBGene00012225, W03G11.3, Putative alpha-L-fucosidase, [RH, Score=424, Expect=4e-145]} {Smed: dd_Smed_v6_8422_0_1, dd_Smed_v6_8422_0_1, [RH, Score=541, Expect=0.0]} {RNA1509_6158} {RNA1310_6463} {RNA815_1561}

Mlig455_046209 {REF} {Length: 3321} {TRANSSPLICED} {Pfam: Alpha-L-fucosidase [PF01120.19, score=417.3]; Alpha-L-fucosidase C-terminal domain [PF16757.7, score=71.3]} {Human: ENSG00000001036, FUCA2, alpha-L-fucosidase 2, [RH, Score=537, Expect=0.0]; ENSG00000179163, FUCA1, alpha-L-fucosidase 1, [RH, Score=518, Expect=0.0]} {Mouse: ENSMUSG00000019810, Fuca2, fucosidase, alpha-L- 2, plasma, [RH, Score=530, Expect=0.0]; ENSMUSG00000028673, Fuca1, fucosidase, alpha-L- 1, tissue, [RH, Score=516, Expect=0.0]} {Dmel: FBgn0285958, Fuca, alpha-L-fucosidase, [RH, Score=466, Expect=1e-161]} {Celegans: WBGene00012225, W03G11.3, Putative alpha-L-fucosidase, [RH, Score=421, Expect=7e-144]} {Smed: dd_Smed_v6_8422_0_1, dd_Smed_v6_8422_0_1, [RH, Score=538, Expect=0.0]} {RNA1509_12330, RNA1509_16238, RNA1509_6158} {RNA1310_9914.1, RNA1509_12330, RNA1509_16238, RNA1509_6158} {RNA1509_12330, RNA1509_16238, RNA1509_6158, RNA815_1561}
67. MligTC455_44887 259 5.39 Mlig455_036907

Neo: Int S/G2/M

Age: -

Region-enriched R5: 2.542/0.00111

1.8 - - - 0.969 - 0.831 Mlig455_036907 {REF} {Length: 3437} {TRANSSPLICED} {RNA1509_19251, RNA1509_43115, RNA1509_55744} {RNA1310_5979.2, RNA1509_43115, RNA1509_55744} {RNA1509_43115, RNA1509_55744, RNA815_3904}
68. MligTC455_40359 779 16.23 Mlig455_025110

Neo: -

Age: -

SNX33 1.799 - - - 0.960 0.839 - Mlig455_025110 {REF} {Length: 4134} {Pfam: WASP-binding domain of Sorting nexin protein [PF10456.11, score=185.6]; PX domain [PF00787.26, score=62.1]; SH3 domain [PF00018.30, score=48.9]; Variant SH3 domain [PF14604.8, score=48.1]; Variant SH3 domain [PF07653.19, score=40.9]} {Human: ENSG00000173548, SNX33, sorting nexin 33, [RH, Score=279, Expect=9e-86]} {Mouse: ENSMUSG00000002365, Snx9, sorting nexin 9, [RH, Score=256, Expect=5e-77]; ENSMUSG00000042364, Snx18, sorting nexin 18, [RH, Score=253, Expect=2e-75]} {Dmel: FBgn0040475, SH3PX1, SH3 and PX domain containing 1, [RH, Score=261, Expect=5e-79]} {Celegans: WBGene00003086, lst-4, Sorting nexin lst-4, [Score=216, Expect=1e-62]} {Smed: dd_Smed_v6_2732_0_1, dd_Smed_v6_2732_0_1, [Score=236, Expect=2e-70]} {RNA1509_11409, RNA1509_45683, RNA1509_47652} {RNA1310_5754, RNA1509_45683, RNA1509_47652} {RNA1509_45683, RNA1509_47652, RNA815_7676.1}
69. MligTC455_48785 525 10.94 Mlig455_045165

Neo: -

Age: -

DCAF7 1.799 0.821 - - 0.978 - - Mlig455_045165 {REF} {Length: 2087} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=26.2]} {Human: ENSG00000136485, DCAF7, DDB1 and CUL4 associated factor 7, [RH, Score=600, Expect=0.0]} {Mouse: ENSMUSG00000049354, Dcaf7, DDB1 and CUL4 associated factor 7, [RH, Score=600, Expect=0.0]} {Dmel: FBgn0266848, wap, wings apart, [RH, Score=577, Expect=0.0]} {Celegans: WBGene00009976, swan-2, Seven WD repeats, AN11 family, [RH, Score=471, Expect=1e-165]} {Smed: dd_Smed_v6_3579_0_1, dd_Smed_v6_3579_0_1, [RH, Score=552, Expect=0.0]} {RNA1509_38686} {RNA1310_14635, RNA1509_38686} {RNA1509_38686, RNA815_37344}
70. MligTC455_38940 212 4.41 Mlig455_054977

Neo: -

Age: -

Region-enriched R5: 2.988/0.04324

USP22 1.798 - - - 0.969 - 0.829 Mlig455_054977 {REF} {Length: 3661} {TRANSSPLICED} {Pfam: Ubiquitin carboxyl-terminal hydrolase [PF00443.31, score=198.6]; Zn-finger in ubiquitin-hydrolases and other protein [PF02148.21, score=43.0]; Ubiquitin carboxyl-terminal hydrolase [PF13423.8, score=37.5]} {Human: ENSG00000124422, USP22, ubiquitin specific peptidase 22, [RH, Score=417, Expect=2e-141]} {Mouse: ENSMUSG00000042506, Usp22, ubiquitin specific peptidase 22, [RH, Score=414, Expect=3e-140]} {Dmel: FBgn0013717, not, non-stop, [RH, Score=374, Expect=5e-125]} {Celegans: WBGene00013506, usp-3, Ubiquitinyl hydrolase 1, [Score=114, Expect=8e-27]} {Smed: dd_Smed_v6_10110_0_2, dd_Smed_v6_10110_0_2, [RH, Score=249, Expect=7e-77]} {RNA1509_29373, RNA1509_34023, RNA1509_48896, RNA1509_59508} {RNA1310_14900, RNA1509_29373, RNA1509_48896, RNA1509_59508} {RNA1509_29373, RNA1509_48896, RNA1509_59508, RNA815_5760.1}
71. MligTC455_12731 331 6.89 Mlig455_005108

Neo: -

Age: -

Region-enriched R6: 3.150/0.01756

1.797 0.843 - - 0.954 - - Mlig455_005108 {REF} {Length: 654} {NoTransDecoderORF} {RNA1509_44841} {RNA1310_66981} {RNA815_54535}
72. MligTC455_30458 451 9.39 Mlig455_062993

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=2.026

FTCD 1.796 0.844 - - 0.952 - - Mlig455_062993 {REF} {Length: 2008} {Pfam: Formiminotransferase domain, N-terminal subdomain [PF07837.14, score=187.7]; Formiminotransferase domain [PF02971.16, score=179.9]; Formiminotransferase-cyclodeaminase [PF04961.14, score=66.0]} {Human: ENSG00000160282, FTCD, formimidoyltransferase cyclodeaminase, [Score=400, Expect=9e-135]; ENSG00000281775, FTCD, formimidoyltransferase cyclodeaminase, [Score=399, Expect=6e-136]} {Mouse: ENSMUSG00000001155, Ftcd, formiminotransferase cyclodeaminase, [Score=402, Expect=7e-136]} {Smed: dd_Smed_v6_7815_0_1, dd_Smed_v6_7815_0_1, [Score=292, Expect=3e-93]} {RNA1509_29292} {RNA1310_13312} {RNA815_5334}
73. MligTC455_37160 1139 23.73 Mlig455_015317, Mlig455_032998, Mlig455_068744

Neo: -

Age: logFC(26M/2M)=-0.355

Region-enriched R2: 1.560/0.01222

TTC28 1.796 0.829 - - 0.967 - -

Mlig455_015317 {REF} {Length: 5958} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF13424.8, score=63.4]; Tetratricopeptide repeat [PF07719.19, score=51.3]; Tetratricopeptide repeat [PF00515.30, score=40.4]; Tetratricopeptide repeat [PF13181.8, score=39.5]; CHAT domain [PF12770.9, score=37.9]; Tetratricopeptide repeat [PF14559.8, score=23.5]; Tetratricopeptide repeat [PF13431.8, score=22.4]; Tetratricopeptide repeat [PF13176.8, score=20.4]} {Human: ENSG00000100154, TTC28, tetratricopeptide repeat domain 28, [Score=69.3, Expect=7e-11]} {Mouse: ENSMUSG00000033209, Ttc28, tetratricopeptide repeat domain 28, [Score=70.9, Expect=2e-11]} {RNA1509_5411} {RNA1310_761.1} {RNA815_600}

Mlig455_032998 {REF} {Length: 5728} {Pfam: CHAT domain [PF12770.9, score=39.2]} {Human: ENSG00000100154, TTC28, tetratricopeptide repeat domain 28, [Score=67.8, Expect=1e-10]} {Mouse: ENSMUSG00000033209, Ttc28, tetratricopeptide repeat domain 28, [Score=69.3, Expect=3e-11]} {RNA1509_5411} {RNA1310_761.1} {RNA815_600}

Mlig455_068744 {REF} {Length: 5980} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF13424.8, score=62.6]; Tetratricopeptide repeat [PF07719.19, score=49.0]; Tetratricopeptide repeat [PF13181.8, score=39.3]; Tetratricopeptide repeat [PF00515.30, score=38.4]; CHAT domain [PF12770.9, score=37.8]; Tetratricopeptide repeat [PF14559.8, score=22.1]; Tetratricopeptide repeat [PF13431.8, score=20.8]; Tetratricopeptide repeat [PF13176.8, score=19.2]} {Human: ENSG00000100154, TTC28, tetratricopeptide repeat domain 28, [Score=66.2, Expect=6e-10]} {Mouse: ENSMUSG00000033209, Ttc28, tetratricopeptide repeat domain 28, [Score=67.8, Expect=1e-10]} {RNA1509_5411} {RNA1310_761.2} {RNA815_600}
74. MligTC455_40609 1438 29.96 Mlig455_048089

Neo: Int S/G2/M

Age: -

Region-enriched R5: 1.233/0.00009

1.791 - - - 0.963 - 0.828 Mlig455_048089 {REF} {Length: 805} {TRANSSPLICED} {RNA1509_36909, RNA1509_50236} {RNA1310_34598, RNA1509_36909, RNA1509_50236} {RNA1509_36909, RNA1509_50236, RNA815_16148}
75. MligTC455_16863 349 7.26 Mlig455_009275

Neo: -

Age: Down-Up-Down

DYRK1B 1.786 0.818 - - 0.968 - - Mlig455_009275 {REF} {Length: 5761} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=162.5]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=82.6]} {Human: ENSG00000281320, DYRK1B, dual specificity tyrosine phosphorylation regulated kinase 1B, [Score=479, Expect=9e-163]; ENSG00000105204, DYRK1B, dual specificity tyrosine phosphorylation regulated kinase 1B, [Score=479, Expect=9e-163]; ENSG00000157540, DYRK1A, dual specificity tyrosine phosphorylation regulated kinase 1A, [Score=469, Expect=1e-157]} {Mouse: ENSMUSG00000002409, Dyrk1b, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b, [Score=480, Expect=3e-162]; ENSMUSG00000022897, Dyrk1a, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a, [Score=470, Expect=5e-158]} {Dmel: FBgn0259168, mnb, minibrain, [Score=495, Expect=1e-169]} {Celegans: WBGene00003149, mbk-1, Dual specificity tyrosine-phosphorylation-regulated kinase mbk-1, [Score=431, Expect=3e-141]} {Smed: dd_Smed_v6_3773_0_1, dd_Smed_v6_3773_0_1, [Score=425, Expect=3e-136]} {RNA1509_9464} {RNA1310_10341} {RNA815_7238.1}
76. MligTC455_46713 631 13.15 Mlig455_022770

Neo: -

Age: -

1.786 - - - 0.974 0.812 - Mlig455_022770 {REF} {Length: 2917} {Celegans: WBGene00019686, K12H6.6, [Score=57.0, Expect=8e-11]} {Smed: dd_Smed_v6_4223_0_3, dd_Smed_v6_4223_0_3, [Score=77.0, Expect=4e-19]} {RNA1509_32604, RNA1509_54558, RNA1509_56093, RNA1509_60001, RNA1509_8810} {RNA1310_3523.1, RNA1509_32604, RNA1509_54558, RNA1509_56093, RNA1509_60001, RNA1509_8810} {RNA1509_32604, RNA1509_54558, RNA1509_56093, RNA1509_60001, RNA1509_8810, RNA815_5817}
77. MligTC455_46731 237 4.94 Mlig455_009017

Neo: -

Age: -

ARFGAP1 1.785 - - - 0.969 - 0.816 Mlig455_009017 {REF} {Length: 3384} {Pfam: Putative GTPase activating protein for Arf [PF01412.20, score=29.7]} {Human: ENSG00000101199, ARFGAP1, ADP ribosylation factor GTPase activating protein 1, [Score=161, Expect=1e-44]} {Mouse: ENSMUSG00000027575, Arfgap1, ADP-ribosylation factor GTPase activating protein 1, [Score=158, Expect=1e-43]} {Dmel: FBgn0020655, ArfGAP1, ADP-ribosylation factor GTPase activating protein 1, [Score=205, Expect=9e-61]} {Celegans: WBGene00010500, K02B12.7, [Score=137, Expect=5e-36]} {Smed: dd_Smed_v6_539_0_1, dd_Smed_v6_539_0_1, [Score=50.8, Expect=8e-07]} {RNA1509_3768} {RNA1310_4307.1} {RNA815_7335}
78. MligTC455_45822 733 15.27 Mlig455_030111, Mlig455_030180

Neo: -

Age: -

Region-enriched R4: 2.554/0.00328

1.783 - - - 0.960 - 0.823

Mlig455_030111 {REF} {Length: 2896} {TRANSSPLICED} {Pfam: Mitotic-spindle organizing gamma-tubulin ring associated [PF12926.9, score=29.8]} {RNA1509_27378, RNA1509_41692} {RNA1310_18834, RNA1509_41692} {RNA1509_41692, RNA815_11733}

Mlig455_030180 {REF} {Length: 2897} {TRANSSPLICED} {Pfam: Mitotic-spindle organizing gamma-tubulin ring associated [PF12926.9, score=29.8]} {RNA1509_27378, RNA1509_49391} {RNA1310_18834, RNA1509_49391} {RNA1509_49391, RNA815_11733}
79. MligTC455_51065 1418 29.55 Mlig455_014301, Mlig455_034467

Neo: -

Age: -

PEX5L 1.782 - - - - 0.951 0.831

Mlig455_014301 {REF} {Length: 2056} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF00515.30, score=90.0]; Tetratricopeptide repeat [PF07719.19, score=80.1]; Tetratricopeptide repeat [PF13432.8, score=69.2]; TPR repeat [PF13414.8, score=58.0]; Tetratricopeptide repeat [PF13428.8, score=54.4]; Tetratricopeptide repeat [PF13181.8, score=51.7]; Tetratricopeptide repeat [PF13431.8, score=47.4]; Tetratricopeptide repeat [PF13424.8, score=46.9]; Tetratricopeptide repeat [PF14559.8, score=43.0]; Tetratricopeptide repeat [PF13176.8, score=40.3]; Tetratricopeptide repeat [PF13174.8, score=29.5]; Tetratricopeptide repeat [PF13371.8, score=27.9]; Tetratricopeptide repeat [PF13374.8, score=23.5]; MIT (microtubule interacting and transport) domain [PF04212.20, score=20.6]} {Human: ENSG00000114757, PEX5L, peroxisomal biogenesis factor 5 like, [RH, Score=228, Expect=3e-67]; ENSG00000139197, PEX5, peroxisomal biogenesis factor 5, [RH, Score=222, Expect=4e-64]} {Mouse: ENSMUSG00000027674, Pex5l, peroxisomal biogenesis factor 5-like, [RH, Score=228, Expect=6e-67]; ENSMUSG00000005069, Pex5, peroxisomal biogenesis factor 5, [RH, Score=228, Expect=1e-66]} {Dmel: FBgn0023516, Pex5, Peroxin 5, [RH, Score=222, Expect=2e-64]} {Celegans: WBGene00004194, prx-5, PeRoXisome assembly factor, [RH, Score=214, Expect=1e-62]} {Smed: dd_Smed_v6_4557_0_1, dd_Smed_v6_4557_0_1, [RH, Score=186, Expect=9e-52]} {RNA1509_18285} {RNA1310_5279.1} {RNA815_20529}

Mlig455_034467 {REF} {Length: 2061} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF00515.30, score=90.0]; Tetratricopeptide repeat [PF07719.19, score=80.1]; Tetratricopeptide repeat [PF13432.8, score=70.5]; TPR repeat [PF13414.8, score=58.0]; Tetratricopeptide repeat [PF13428.8, score=54.2]; Tetratricopeptide repeat [PF13181.8, score=51.7]; Tetratricopeptide repeat [PF13431.8, score=47.2]; Tetratricopeptide repeat [PF13424.8, score=46.7]; Tetratricopeptide repeat [PF14559.8, score=42.9]; Tetratricopeptide repeat [PF13176.8, score=40.3]; Tetratricopeptide repeat [PF13174.8, score=29.6]; Tetratricopeptide repeat [PF13371.8, score=28.6]; Tetratricopeptide repeat [PF13374.8, score=23.5]; MIT (microtubule interacting and transport) domain [PF04212.20, score=20.5]} {Human: ENSG00000114757, PEX5L, peroxisomal biogenesis factor 5 like, [RH, Score=228, Expect=1e-66]; ENSG00000139197, PEX5, peroxisomal biogenesis factor 5, [RH, Score=222, Expect=3e-64]} {Mouse: ENSMUSG00000005069, Pex5, peroxisomal biogenesis factor 5, [RH, Score=228, Expect=9e-67]; ENSMUSG00000027674, Pex5l, peroxisomal biogenesis factor 5-like, [RH, Score=228, Expect=8e-67]} {Dmel: FBgn0023516, Pex5, Peroxin 5, [RH, Score=223, Expect=4e-65]} {Celegans: WBGene00004194, prx-5, PeRoXisome assembly factor, [RH, Score=213, Expect=3e-62]} {Smed: dd_Smed_v6_4557_0_1, dd_Smed_v6_4557_0_1, [RH, Score=189, Expect=9e-53]} {RNA1509_18285} {RNA1310_5279.1} {RNA815_20529}
80. MligTC455_20965 992 20.66 Mlig455_067700

Neo: Int S/G2/M

Age: Up-Down-Up, logFC(26M/2M)=0.716

FDPS 1.781 - - 0.809 0.972 - - Mlig455_067700 {REF} {Length: 1960} {TRANSSPLICED} {Pfam: Polyprenyl synthetase [PF00348.19, score=162.5]} {Human: ENSG00000160752, FDPS, farnesyl diphosphate synthase, [Score=139, Expect=4e-37]} {Mouse: ENSMUSG00000105204, Gm43738, predicted gene 43738, [RH, Score=144, Expect=1e-37]} {Dmel: FBgn0025373, Fpps, Farnesyl pyrophosphate synthase, [Score=154, Expect=6e-43]} {Celegans: WBGene00011058, fdps-1, Farnesyl DiPhosphate Synthetase, [Score=113, Expect=2e-28]} {Smed: dd_Smed_v6_13592_0_1, dd_Smed_v6_13592_0_1, [Score=141, Expect=5e-39]} {RNA1509_43196, RNA1509_46820} {RNA1310_14434, RNA1509_43196} {RNA1509_43196, RNA815_12356}
81. MligTC455_39376 626 13.04 Mlig455_039473

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.343

Region-enriched R5: 1.874/0.00059
Region-enriched R4: 1.747/0.01145

FUCA2 1.78 - - - 0.979 - 0.801 Mlig455_039473 {REF} {Length: 3228} {TRANSSPLICED} {Pfam: Alpha-L-fucosidase [PF01120.19, score=414.4]; Alpha-L-fucosidase C-terminal domain [PF16757.7, score=71.4]} {Human: ENSG00000001036, FUCA2, alpha-L-fucosidase 2, [RH, Score=541, Expect=0.0]; ENSG00000179163, FUCA1, alpha-L-fucosidase 1, [RH, Score=519, Expect=0.0]} {Mouse: ENSMUSG00000019810, Fuca2, fucosidase, alpha-L- 2, plasma, [RH, Score=534, Expect=0.0]; ENSMUSG00000028673, Fuca1, fucosidase, alpha-L- 1, tissue, [RH, Score=516, Expect=0.0]} {Dmel: FBgn0285958, Fuca, alpha-L-fucosidase, [RH, Score=464, Expect=1e-160]} {Celegans: WBGene00012225, W03G11.3, Putative alpha-L-fucosidase, [RH, Score=422, Expect=2e-144]} {Smed: dd_Smed_v6_8422_0_1, dd_Smed_v6_8422_0_1, [RH, Score=540, Expect=0.0]} {RNA1509_32265, RNA1509_55653, RNA1509_6158} {RNA1310_6463, RNA1509_32265, RNA1509_55653} {RNA1509_32265, RNA1509_55653, RNA815_1561}
82. MligTC455_24710 602 12.55 Mlig455_005252

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.680

1.78 0.955 - - - 0.825 - Mlig455_005252 {REF} {Length: 971} {TRANSSPLICED} {Pfam: Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) [PF05793.14, score=19.9]; Protein of unknown function (DUF3752) [PF12572.10, score=19.9]} {RNA1509_13180} {RNA1310_33597.1} {RNA815_34409}
83. MligTC455_23552 539 11.23 Mlig455_020886

Neo: Irradiation

Age: -

CSNK1G1 1.779 - - - 0.960 - 0.819 Mlig455_020886 {REF} {Length: 4055} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=100.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=55.0]; Fungal protein kinase [PF17667.3, score=29.4]} {Human: ENSG00000169118, CSNK1G1, casein kinase 1 gamma 1, [RH, Score=527, Expect=0.0]; ENSG00000151292, CSNK1G3, casein kinase 1 gamma 3, [RH, Score=524, Expect=0.0]} {Mouse: ENSMUSG00000032384, Csnk1g1, casein kinase 1, gamma 1, [RH, Score=535, Expect=0.0]; ENSMUSG00000073563, Csnk1g3, casein kinase 1, gamma 3, [RH, Score=520, Expect=0.0]} {Dmel: FBgn0250823, gish, gilgamesh, [RH, Score=515, Expect=0.0]} {Celegans: WBGene00013709, csnk-1, Casein kinase I gamma, [RH, Score=513, Expect=0.0]} {Smed: dd_Smed_v6_8508_0_2, dd_Smed_v6_8508_0_2, [RH, Score=462, Expect=1e-161]} {RNA1509_20026, RNA1509_31077} {RNA1310_19544.3, RNA1509_31077} {RNA1509_31077, RNA815_13120.1}
84. MligTC455_39133 322 6.7 Mlig455_036429

Neo: -

Age: Down-Up-Up

COPS6 1.779 - - - 0.957 - 0.822 Mlig455_036429 {REF} {Length: 2651} {TRANSSPLICED} {Pfam: Maintenance of mitochondrial structure and function [PF13012.8, score=85.9]; JAB1/Mov34/MPN/PAD-1 ubiquitin protease [PF01398.23, score=43.1]} {Human: ENSG00000168090, COPS6, COP9 signalosome subunit 6, [RH, Score=243, Expect=6e-78]} {Mouse: ENSMUSG00000019494, Cops6, COP9 signalosome subunit 6, [RH, Score=239, Expect=1e-76]} {Dmel: FBgn0028837, CSN6, COP9 signalosome subunit 6, [RH, Score=233, Expect=3e-74]} {Celegans: WBGene00004464, rpn-8, Proteasome Regulatory Particle, Non-ATPase-like, [Score=89.0, Expect=1e-19]} {Smed: dd_Smed_v6_4168_0_1, dd_Smed_v6_4168_0_1, [RH, Score=131, Expect=1e-35]} {RNA1509_12499} {RNA1310_25406.1, RNA1509_12499} {RNA1509_12499, RNA815_12821.1}
85. MligTC455_48391 504 10.5 Mlig455_065506

Neo: -

Age: Up-Down-Down

A1CF 1.779 - - - 0.968 0.811 - Mlig455_065506 {REF} {Length: 4866} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=114.0]; RNA recognition motif [PF16367.7, score=29.0]; double strand RNA binding domain from DEAD END PROTEIN 1 [PF14709.9, score=26.7]} {Human: ENSG00000148584, A1CF, APOBEC1 complementation factor, [Score=414, Expect=1e-133]} {Mouse: ENSMUSG00000052595, A1cf, APOBEC1 complementation factor, [Score=400, Expect=2e-128]; ENSMUSG00000070780, Rbm47, RNA binding motif protein 47, [Score=394, Expect=4e-126]} {Dmel: FBgn0038826, Syp, Syncrip, [Score=333, Expect=1e-102]} {Celegans: WBGene00002000, hrp-2, HnRNP A1 homolog, [Score=275, Expect=3e-81]} {Smed: dd_Smed_v6_2228_0_1, dd_Smed_v6_2228_0_1, [Score=441, Expect=2e-143]} {RNA1509_1358} {RNA1310_15318} {RNA815_6951}
86. MligTC455_17189 979 20.39 Mlig455_060262

Neo: -

Age: Down-Down-Up

MCRS1 1.778 - - - 0.953 0.825 - Mlig455_060262 {REF} {Length: 2447} {TRANSSPLICED} {Pfam: N-terminal region of micro-spherule protein [PF13325.8, score=88.1]} {Human: ENSG00000187778, MCRS1, microspherule protein 1, [Score=90.5, Expect=3e-19]} {Mouse: ENSMUSG00000037570, Mcrs1, microspherule protein 1, [Score=93.2, Expect=2e-20]} {Dmel: FBgn0263832, Rcd5, Reduction in Cnn dots 5, [Score=80.1, Expect=4e-16]} {Celegans: WBGene00018026, F35A5.4, [Score=48.9, Expect=4e-06]} {Smed: dd_Smed_v6_4102_0_1, dd_Smed_v6_4102_0_1, [Score=77.8, Expect=1e-15]} {RNA1509_8483} {RNA1310_19335} {RNA815_6260}
87. MligTC455_24056 471 9.81 Mlig455_042968

Neo: -

Age: -

NDUFS1 1.778 - - - 0.954 0.824 - Mlig455_042968 {REF} {Length: 2756} {TRANSSPLICED} {Pfam: Molybdopterin oxidoreductase [PF00384.24, score=207.2]; 2Fe-2S iron-sulfur cluster binding domain [PF13510.8, score=69.7]; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region [PF10588.11, score=56.4]; NADH-ubiquinone oxidoreductase subunit G, C-terminal [PF09326.13, score=55.9]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=31.5]} {Human: ENSG00000023228, NDUFS1, NADH:ubiquinone oxidoreductase core subunit S1, [RH, Score=952, Expect=0.0]; ENSG00000283447, NDUFS1, NADH:ubiquinone oxidoreductase core subunit S1, [RH, Score=952, Expect=0.0]} {Mouse: ENSMUSG00000025968, Ndufs1, NADH:ubiquinone oxidoreductase core subunit S1, [RH, Score=941, Expect=0.0]} {Dmel: FBgn0017566, ND-75, NADH dehydrogenase (ubiquinone) 75 kDa subunit, [RH, Score=896, Expect=0.0]} {Celegans: WBGene00021562, nuo-5, NADH Ubiquinone Oxidoreductase, [RH, Score=823, Expect=0.0]} {Smed: dd_Smed_v6_2402_0_1, dd_Smed_v6_2402_0_1, [RH, Score=929, Expect=0.0]} {RNA1509_8925} {RNA1310_6597} {RNA815_1467.1}
88. MligTC455_45486 487 10.14 Mlig455_019746

Neo: -

Age: Down-Up-Up

DLG2 1.777 0.951 - - - 0.826 - Mlig455_019746 {REF} {Length: 3340} {Pfam: Guanylate kinase [PF00625.23, score=164.7]; PDZ domain [PF00595.26, score=69.8]; PDZ domain [PF17820.3, score=37.7]; SH3 domain [PF00018.30, score=33.0]; Variant SH3 domain [PF07653.19, score=27.2]; PDZ domain [PF13180.8, score=22.1]; Variant SH3 domain [PF14604.8, score=20.5]; Procyclic acidic repetitive protein (PARP) [PF05887.13, score=19.1]} {Human: ENSG00000150672, DLG2, discs large MAGUK scaffold protein 2, [RH, Score=427, Expect=6e-141]} {Mouse: ENSMUSG00000052572, Dlg2, discs large MAGUK scaffold protein 2, [RH, Score=426, Expect=1e-140]} {Dmel: FBgn0001624, dlg1, discs large 1, [Score=434, Expect=1e-141]} {Celegans: WBGene00001006, dlg-1, Drosophila Discs LarGe homolog; MAGUK protein DLG-1; SAP97-like protein DLG-1, [RH, Score=343, Expect=9e-107]} {Smed: dd_Smed_v6_8511_0_1, dd_Smed_v6_8511_0_1, [RH, Score=317, Expect=2e-101]} {RNA1509_16120, RNA1509_26114} {RNA1310_2555.1, RNA1509_16120} {RNA1509_16120, RNA815_2319}
89. MligTC455_37890 984 20.5 Mlig455_042120

Neo: -

Age: Up-Down-Down

MOB1B 1.776 - - - 0.969 - 0.807 Mlig455_042120 {REF} {Length: 5175} {TRANSSPLICED} {Pfam: Mob1/phocein family [PF03637.19, score=262.4]} {Human: ENSG00000173542, MOB1B, MOB kinase activator 1B, [RH, Score=374, Expect=1e-132]; ENSG00000114978, MOB1A, MOB kinase activator 1A, [RH, Score=371, Expect=1e-131]} {Mouse: ENSMUSG00000006262, Mob1b, MOB kinase activator 1B, [RH, Score=374, Expect=7e-133]; ENSMUSG00000043131, Mob1a, MOB kinase activator 1A, [RH, Score=371, Expect=1e-131]} {Dmel: FBgn0038965, mats, mob as tumor suppressor, [RH, Score=368, Expect=1e-130]} {Celegans: WBGene00020447, mob-3, [Score=223, Expect=3e-73]} {Smed: dd_Smed_v6_6548_0_1, dd_Smed_v6_6548_0_1, [RH, Score=370, Expect=3e-131]} {RNA1509_17457, RNA1509_35281, RNA1509_9427} {RNA1310_36797, RNA1509_17457, RNA1509_35281, RNA1509_9427} {RNA1509_17457, RNA1509_35281, RNA1509_9427, RNA815_14863}
90. MligTC455_29503 492 10.25 Mlig455_059808

Neo: -

Age: -

SZT2 1.774 - - - 0.970 - 0.804 Mlig455_059808 {REF} {Length: 13680} {TRANSSPLICED} {Human: ENSG00000198198, SZT2, SZT2, KICSTOR complex subunit, [RH, Score=325, Expect=9e-88]} {Mouse: ENSMUSG00000033253, Szt2, seizure threshold 2, [RH, Score=330, Expect=1e-89]} {Celegans: WBGene00010013, F54B3.1, [RH, Score=112, Expect=7e-24]} {Smed: dd_Smed_v6_8946_0_1, dd_Smed_v6_8946_0_1, [Score=111, Expect=1e-23]} {RNA1509_25909, RNA1509_3648} {RNA1310_92.1, RNA1509_25909, RNA1509_3648} {RNA1509_25909, RNA1509_3648, RNA815_12089}
91. MligTC455_11502 179 3.73 Mlig455_062843

Neo: Int S/G2/M

Age: Down-Up-Down

UHRF1 1.772 - - 0.799 0.973 - - Mlig455_062843 {REF} {Length: 2536} {TRANSSPLICED} {Pfam: SAD/SRA domain [PF02182.19, score=169.0]} {Human: ENSG00000276043, UHRF1, ubiquitin like with PHD and ring finger domains 1, [Score=152, Expect=3e-38]} {Mouse: ENSMUSG00000001228, Uhrf1, ubiquitin-like, containing PHD and RING finger domains, 1, [Score=154, Expect=3e-39]} {RNA1509_25446} {RNA1310_8743} {RNA815_6882}
92. MligTC455_23551 537 11.19 Mlig455_007655

Neo: -

Age: -

CSNK1G1 1.772 - - - 0.960 - 0.812 Mlig455_007655 {REF} {Length: 4258} {Pfam: Protein kinase domain [PF00069.27, score=100.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=55.0]; Fungal protein kinase [PF17667.3, score=29.3]} {Human: ENSG00000169118, CSNK1G1, casein kinase 1 gamma 1, [RH, Score=527, Expect=0.0]; ENSG00000151292, CSNK1G3, casein kinase 1 gamma 3, [RH, Score=521, Expect=0.0]} {Mouse: ENSMUSG00000032384, Csnk1g1, casein kinase 1, gamma 1, [RH, Score=535, Expect=0.0]; ENSMUSG00000073563, Csnk1g3, casein kinase 1, gamma 3, [RH, Score=518, Expect=0.0]} {Dmel: FBgn0250823, gish, gilgamesh, [RH, Score=508, Expect=4e-178]} {Celegans: WBGene00013709, csnk-1, Casein kinase I gamma, [RH, Score=512, Expect=0.0]} {Smed: dd_Smed_v6_8508_0_2, dd_Smed_v6_8508_0_2, [RH, Score=462, Expect=2e-161]} {RNA1509_16024, RNA1509_20026} {RNA1310_20582.1, RNA1509_16024} {RNA1509_16024, RNA815_13120.1}
93. MligTC455_45376 648 13.5 Mlig455_035112

Neo: -

Age: logFC(26M/2M)=0.360

PFKFB1 1.771 - - - 0.967 0.804 - Mlig455_035112 {REF} {Length: 2708} {Pfam: 6-phosphofructo-2-kinase [PF01591.20, score=288.1]; Histidine phosphatase superfamily (branch 1) [PF00300.24, score=129.5]; AAA domain [PF13671.8, score=26.8]} {Human: ENSG00000158571, PFKFB1, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1, [RH, Score=522, Expect=0.0]; ENSG00000123836, PFKFB2, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2, [RH, Score=506, Expect=9e-176]; ENSG00000114268, PFKFB4, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4, [RH, Score=502, Expect=1e-174]; ENSG00000170525, PFKFB3, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3, [RH, Score=496, Expect=1e-171]} {Mouse: ENSMUSG00000025271, Pfkfb1, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1, [RH, Score=522, Expect=0.0]; ENSMUSG00000026773, Pfkfb3, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3, [RH, Score=505, Expect=5e-176]; ENSMUSG00000025648, Pfkfb4, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4, [RH, Score=504, Expect=2e-175]; ENSMUSG00000026409, Pfkfb2, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2, [RH, Score=500, Expect=8e-174]} {Dmel: FBgn0027621, Pfrx, 6-phosphofructo-2-kinase, [RH, Score=485, Expect=9e-165]} {Celegans: WBGene00019295, pfkb-1.2, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 6-phosphofructo-2-kinase Fructose-2,6-bisphosphatase, [RH, Score=451, Expect=3e-155]} {Smed: dd_Smed_v6_3959_0_1, dd_Smed_v6_3959_0_1, [RH, Score=533, Expect=0.0]} {RNA1509_15746} {RNA1310_8036.1} {RNA815_2585.1}
94. MligTC455_51890 405 8.43 Mlig455_057301

Neo: -

Age: Up-Up-Down

NVL 1.771 - - - 0.970 - 0.801 Mlig455_057301 {REF} {Length: 3713} {TRANSSPLICED} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=172.7]; AAA+ lid domain [PF17862.3, score=29.5]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=28.2]; AAA domain [PF13401.8, score=27.0]; AAA ATPase domain [PF13191.8, score=25.9]; AAA domain [PF13521.8, score=24.7]; NACHT domain [PF05729.14, score=23.8]; AAA domain [PF13238.8, score=22.6]; AAA domain (dynein-related subfamily) [PF07728.16, score=21.1]; AAA domain [PF13671.8, score=21.0]; AAA domain (Cdc48 subfamily) [PF07724.16, score=20.6]} {Human: ENSG00000143748, NVL, nuclear VCP-like, [Score=259, Expect=7e-74]} {Mouse: ENSMUSG00000026516, Nvl, nuclear VCP-like, [Score=255, Expect=1e-72]} {Dmel: FBgn0016983, smid, smallminded, [Score=215, Expect=1e-58]} {Celegans: WBGene00003119, mac-1, Member of AAA family binding CED-4, [Score=237, Expect=9e-67]} {Smed: dd_Smed_v6_482_0_1, dd_Smed_v6_482_0_1, [Score=192, Expect=4e-51]} {RNA1509_11463} {RNA1310_4277.1} {RNA815_2542}
95. MligTC455_52338 341 7.1 Mlig455_008924

Neo: Int S/G2/M

Age: logFC(26M/2M)=0.465

C2orf76 1.771 0.957 - - - - 0.814 Mlig455_008924 {REF} {Length: 2124} {TRANSSPLICED} {Pfam: Uncharacterized conserved protein (DUF2340) [PF10209.11, score=127.4]} {Human: ENSG00000186132, C2orf76, chromosome 2 open reading frame 76, [RH, Score=97.1, Expect=2e-26]} {Mouse: ENSMUSG00000026388, 3110009E18Rik, RIKEN cDNA 3110009E18 gene, [RH, Score=92.0, Expect=1e-24]} {RNA1509_25259, RNA1509_33285} {RNA1310_9901.1, RNA1509_25259, RNA1509_33285} {RNA1509_25259, RNA1509_33285, RNA815_28452}
96. MligTC455_43166 2766 57.63 Mlig455_039958, Mlig455_039971

Neo: -

Age: -

SNAPIN 1.77 - - - 0.950 0.820 -

Mlig455_039958 {REF} {Length: 937} {TRANSSPLICED} {Pfam: Snapin/Pallidin [PF14712.8, score=80.8]} {Human: ENSG00000143553, SNAPIN, SNAP associated protein, [RH, Score=114, Expect=1e-32]} {Mouse: ENSMUSG00000001018, Snapin, SNAP-associated protein, [RH, Score=110, Expect=1e-31]} {Dmel: FBgn0031455, Snapin, SNAP associated protein, [RH, Score=62.0, Expect=7e-13]} {Celegans: WBGene00015327, snpn-1, SNAPIN protein homolog, [RH, Score=44.3, Expect=2e-06]} {Smed: dd_Smed_v6_1781_0_1, dd_Smed_v6_1781_0_1, [RH, Score=101, Expect=2e-28]} {RNA1509_8939} {RNA1310_10828} {RNA815_7128}

Mlig455_039971 {REF} {Length: 2282} {Pfam: Snapin/Pallidin [PF14712.8, score=80.6]} {Human: ENSG00000143553, SNAPIN, SNAP associated protein, [RH, Score=113, Expect=2e-32]} {Mouse: ENSMUSG00000001018, Snapin, SNAP-associated protein, [RH, Score=110, Expect=3e-31]} {Dmel: FBgn0031455, Snapin, SNAP associated protein, [RH, Score=62.4, Expect=6e-13]} {Celegans: WBGene00015327, snpn-1, SNAPIN protein homolog, [RH, Score=44.7, Expect=2e-06]} {Smed: dd_Smed_v6_1781_0_1, dd_Smed_v6_1781_0_1, [RH, Score=99.4, Expect=2e-27]} {RNA1509_8939} {RNA1310_10828, RNA1509_8939} {RNA1509_8939, RNA815_7128}
97. MligTC455_26331 628 13.09 Mlig455_008523, Mlig455_008551

Neo: -

Age: -

ELL 1.767 - - - 0.969 - 0.798

Mlig455_008523 {REF} {Length: 4459} {Pfam: RNA polymerase II elongation factor ELL [PF10390.11, score=81.2]; Occludin homology domain [PF07303.15, score=61.2]} {Human: ENSG00000105656, ELL, elongation factor for RNA polymerase II, [RH, Score=80.5, Expect=1e-15]} {Mouse: ENSMUSG00000001542, Ell2, elongation factor RNA polymerase II 2, [Score=73.6, Expect=2e-13]; ENSMUSG00000070002, Ell, elongation factor RNA polymerase II, [Score=72.8, Expect=3e-13]} {Dmel: FBgn0014037, Su(Tpl), [Score=53.1, Expect=4e-07]} {Smed: dd_Smed_v6_7663_0_1, dd_Smed_v6_7663_0_1, [Score=49.3, Expect=4e-06]} {RNA1509_33136} {RNA1310_18659} {RNA815_16234}

Mlig455_008551 {REF} {Length: 4755} {Pfam: RNA polymerase II elongation factor ELL [PF10390.11, score=81.8]; Occludin homology domain [PF07303.15, score=59.9]} {Human: ENSG00000105656, ELL, elongation factor for RNA polymerase II, [RH, Score=80.1, Expect=2e-15]} {Mouse: ENSMUSG00000001542, Ell2, elongation factor RNA polymerase II 2, [Score=74.3, Expect=1e-13]; ENSMUSG00000070002, Ell, elongation factor RNA polymerase II, [Score=73.6, Expect=2e-13]} {Dmel: FBgn0014037, Su(Tpl), [Score=54.3, Expect=2e-07]} {Smed: dd_Smed_v6_7663_0_1, dd_Smed_v6_7663_0_1, [Score=48.5, Expect=8e-06]} {RNA1509_33136, RNA1509_37731} {RNA1310_18659, RNA1509_33136, RNA1509_37731} {RNA1509_33136, RNA1509_37731, RNA815_16234}
98. MligTC455_45171 1046 21.78 Mlig455_021707

Neo: Int S/G2/M

Age: Down-Down-Up

Region-enriched R5: 1.179/0.00012

EXOSC6 1.767 0.959 - - - - 0.808 Mlig455_021707 {REF} {Length: 1052} {TRANSSPLICED} {Pfam: 3' exoribonuclease family, domain 1 [PF01138.23, score=89.5]} {Human: ENSG00000223496, EXOSC6, exosome component 6, [RH, Score=73.9, Expect=8e-15]} {Mouse: ENSMUSG00000109941, Exosc6, exosome component 6, [RH, Score=81.3, Expect=1e-17]} {Dmel: FBgn0036916, Mtr3, [RH, Score=82.4, Expect=8e-18]} {Celegans: WBGene00007201, exos-4.1, Putative exosome complex component RRP41, [Score=62.8, Expect=2e-11]} {Smed: dd_Smed_v6_5027_0_1, dd_Smed_v6_5027_0_1, [RH, Score=95.5, Expect=2e-23]} {RNA1509_30702} {RNA1310_33695, RNA1509_30702} {RNA1509_30702, RNA815_25968}
99. MligTC455_50675 648 13.5 Mlig455_017899

Neo: -

Age: -

1.766 - - - 0.958 - 0.808 Mlig455_017899 {REF} {Length: 2179} {RNA1509_14147, RNA1509_51574, RNA1509_53971} {RNA1310_35088, RNA1509_14147, RNA1509_51574, RNA1509_53971} {RNA1509_14147, RNA1509_51574, RNA1509_53971, RNA815_14923}
100. MligTC455_00831 642 13.37 Mlig455_016457, Mlig455_016523

Neo: -

Age: logFC(26M/2M)=0.506

LGR5 1.764 0.799 - - 0.965 - -

Mlig455_016457 {REF} {Length: 4347} {Pfam: Leucine rich repeat [PF13855.8, score=86.3]; Leucine Rich repeats (2 copies) [PF12799.9, score=45.8]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=40.5]} {Human: ENSG00000139292, LGR5, leucine rich repeat containing G protein-coupled receptor 5, [Score=58.5, Expect=7e-08]; ENSG00000145147, SLIT2, slit guidance ligand 2, [Score=57.0, Expect=2e-07]} {Mouse: ENSMUSG00000020140, Lgr5, leucine rich repeat containing G protein coupled receptor 5, [Score=59.7, Expect=2e-08]} {Dmel: FBgn0267435, chp, chaoptin, [Score=67.0, Expect=8e-11]} {Celegans: WBGene00006593, tol-1, TOLl (Drosophila) family, [Score=55.8, Expect=2e-07]} {RNA1509_8817} {RNA1310_2409} {RNA815_590.1}

Mlig455_016523 {REF} {Length: 3360} {Pfam: Leucine rich repeat [PF13855.8, score=41.7]; Leucine Rich repeats (2 copies) [PF12799.9, score=39.1]} {RNA1509_8817} {RNA1310_22547} {RNA815_590.1}

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