Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_33086 | 335 | 6.97 | Mlig455_067414, Mlig455_069549 | Neo: - Age: Up-Down-Up Region-enriched R7: 2.760/0.00678 |
BRAF | Mlig455_067414 {REF} {Length: 2697} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=79.5]; Protein kinase domain [PF00069.27, score=54.0]; Kinase-like [PF14531.8, score=30.9]} {Human: ENSG00000157764, BRAF, B-Raf proto-oncogene, serine/threonine kinase, [Score=79.0, Expect=2e-16]; ENSG00000141068, KSR1, kinase suppressor of ras 1, [Score=77.4, Expect=8e-16]} {Mouse: ENSMUSG00000018334, Ksr1, kinase suppressor of ras 1, [Score=80.5, Expect=5e-17]; ENSMUSG00000002413, Braf, Braf transforming gene, [Score=79.0, Expect=1e-16]} {Dmel: FBgn0003079, Raf, Raf oncogene, [Score=79.3, Expect=8e-17]} {Celegans: WBGene00002239, ksr-1, Kinase suppressor of Ras A, [Score=87.8, Expect=8e-20]} {Smed: dd_Smed_v6_8845_0_1, dd_Smed_v6_8845_0_1, [Score=190, Expect=1e-56]} {RNA1509_56455} {RNA1310_52842} {RNA815_31190} Mlig455_069549 {REF} {Length: 2704} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=79.5]; Protein kinase domain [PF00069.27, score=54.0]; Kinase-like [PF14531.8, score=30.9]} {Human: ENSG00000157764, BRAF, B-Raf proto-oncogene, serine/threonine kinase, [Score=79.0, Expect=2e-16]; ENSG00000141068, KSR1, kinase suppressor of ras 1, [Score=77.4, Expect=8e-16]} {Mouse: ENSMUSG00000018334, Ksr1, kinase suppressor of ras 1, [Score=80.5, Expect=5e-17]; ENSMUSG00000002413, Braf, Braf transforming gene, [Score=79.0, Expect=1e-16]} {Dmel: FBgn0003079, Raf, Raf oncogene, [Score=79.3, Expect=8e-17]} {Celegans: WBGene00002239, ksr-1, Kinase suppressor of Ras A, [Score=87.8, Expect=8e-20]} {Smed: dd_Smed_v6_8845_0_1, dd_Smed_v6_8845_0_1, [Score=190, Expect=1e-56]} {RNA1509_56455} {RNA1310_12825} {RNA815_31190} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -5.724 | 3.051 | 0.17434 | 0.80056 | |
RegionR2 | 0.326 | 3.051 | 0.71014 | 1.00000 | |
RegionR3 | 0.65 | 3.051 | 0.48016 | 0.98275 | |
RegionR4 | -0.003 | 3.051 | 0.85288 | 1.00000 | |
RegionR5 | -1.493 | 3.051 | 0.99631 | 1.00000 | |
RegionR6 | 1.608 | 3.051 | 0.02764 | 0.30550 | |
RegionR7 | 2.76 | 3.051 | 0.00012 | 0.00678 | |
RegionR8 | 1.875 | 3.051 | 0.06885 | 0.50396 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | 7.88 | 3.051 | 0.02440 | 0.59347 | |
RegenerationR2 | 1.267 | 3.051 | 0.03062 | 0.28834 | |
RegenerationR3 | 0.602 | 3.051 | 0.35909 | 0.77586 | |
RegenerationR4 | -0.2 | 3.051 | 0.76910 | 0.97656 | |
RegenerationR5 | 1.58 | 3.051 | 0.02145 | 0.25338 | |
RegenerationR6 | 0.232 | 3.051 | 0.69093 | 0.91937 | |
RegenerationBL | -1.876 | 3.051 | 0.02365 | 0.16887 | |
RegenerationTP | -0.156 | 3.051 | 0.82132 | 1.00000 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_33086 | 335 | 6.97 | Mlig455_067414, Mlig455_069549 | Neo: - Age: Up-Down-Up Region-enriched R7: 2.760/0.00678 |
BRAF | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_067414 {REF} {Length: 2697} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=79.5]; Protein kinase domain [PF00069.27, score=54.0]; Kinase-like [PF14531.8, score=30.9]} {Human: ENSG00000157764, BRAF, B-Raf proto-oncogene, serine/threonine kinase, [Score=79.0, Expect=2e-16]; ENSG00000141068, KSR1, kinase suppressor of ras 1, [Score=77.4, Expect=8e-16]} {Mouse: ENSMUSG00000018334, Ksr1, kinase suppressor of ras 1, [Score=80.5, Expect=5e-17]; ENSMUSG00000002413, Braf, Braf transforming gene, [Score=79.0, Expect=1e-16]} {Dmel: FBgn0003079, Raf, Raf oncogene, [Score=79.3, Expect=8e-17]} {Celegans: WBGene00002239, ksr-1, Kinase suppressor of Ras A, [Score=87.8, Expect=8e-20]} {Smed: dd_Smed_v6_8845_0_1, dd_Smed_v6_8845_0_1, [Score=190, Expect=1e-56]} {RNA1509_56455} {RNA1310_52842} {RNA815_31190} Mlig455_069549 {REF} {Length: 2704} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=79.5]; Protein kinase domain [PF00069.27, score=54.0]; Kinase-like [PF14531.8, score=30.9]} {Human: ENSG00000157764, BRAF, B-Raf proto-oncogene, serine/threonine kinase, [Score=79.0, Expect=2e-16]; ENSG00000141068, KSR1, kinase suppressor of ras 1, [Score=77.4, Expect=8e-16]} {Mouse: ENSMUSG00000018334, Ksr1, kinase suppressor of ras 1, [Score=80.5, Expect=5e-17]; ENSMUSG00000002413, Braf, Braf transforming gene, [Score=79.0, Expect=1e-16]} {Dmel: FBgn0003079, Raf, Raf oncogene, [Score=79.3, Expect=8e-17]} {Celegans: WBGene00002239, ksr-1, Kinase suppressor of Ras A, [Score=87.8, Expect=8e-20]} {Smed: dd_Smed_v6_8845_0_1, dd_Smed_v6_8845_0_1, [Score=190, Expect=1e-56]} {RNA1509_56455} {RNA1310_12825} {RNA815_31190} |
2. | MligTC455_43399 | 689 | 14.36 | Mlig455_030001, Mlig455_030008 | Neo: - Age: - |
HS3ST5 | 1.734 | - | - | - | 0.781 | 0.953 | - | Mlig455_030001 {REF} {Length: 2130} {Pfam: Sulfotransferase domain [PF00685.29, score=76.0]; Sulfotransferase family [PF13469.8, score=40.8]} {Human: ENSG00000249853, HS3ST5, heparan sulfate-glucosamine 3-sulfotransferase 5, [Score=209, Expect=7e-65]; ENSG00000002587, HS3ST1, heparan sulfate-glucosamine 3-sulfotransferase 1, [Score=201, Expect=6e-62]} {Mouse: ENSMUSG00000044499, Hs3st5, heparan sulfate (glucosamine) 3-O-sulfotransferase 5, [Score=209, Expect=6e-65]; ENSMUSG00000051022, Hs3st1, heparan sulfate (glucosamine) 3-O-sulfotransferase 1, [Score=202, Expect=2e-62]} {Dmel: FBgn0031005, Hs3st-B, Heparan sulfate 3-O sulfotransferase-B, [Score=178, Expect=8e-53]} {Celegans: WBGene00002030, hst-3.1, Heparan SulphoTransferase, [RH, Score=179, Expect=4e-54]} {Smed: dd_Smed_v6_81402_0_1, dd_Smed_v6_81402_0_1, [Score=99.0, Expect=7e-25]} {RNA1509_25917} {RNA1310_19255} {RNA815_9074} Mlig455_030008 {REF} {Length: 625} {NoTransDecoderORF} {RNA1310_39969.1} {RNA815_21299} |
3. | MligTC455_45782 | 152 | 3.16 | Mlig455_024298 | Neo: - Age: Down-Up-Down |
1.69 | 0.713 | - | - | - | 0.977 | - | Mlig455_024298 {REF} {Length: 1820} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_30876} {RNA1310_11070} {RNA815_44674} | |
4. | MligTC455_08684 | 106 | 2.2 | Mlig455_002682 | Neo: - Age: - |
0.982 | - | - | - | 0.982 | - | - | Mlig455_002682 {REF} {Length: 439} {NoTransDecoderORF} | |
5. | MligTC455_52917 | 35 | 0.74 | Mlig455_038643 | Neo: - Age: - |
0.966 | - | - | - | - | 0.966 | - | Mlig455_038643 {REF} {Length: 4209} {NoTransDecoderORF} {RNA1509_49908} {RNA1310_28346} {RNA815_54494} | |
6. | MligTC455_18113 | 419 | 8.72 | Mlig455_056777 | Neo: - Age: - |
FCN2 | 0.961 | - | - | - | - | - | 0.961 | Mlig455_056777 {REF} {Length: 1935} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=150.8]} {Human: ENSG00000160339, FCN2, ficolin 2, [Score=113, Expect=1e-28]; ENSG00000085265, FCN1, ficolin 1, [Score=112, Expect=3e-28]; ENSG00000130720, FIBCD1, fibrinogen C domain containing 1, [Score=112, Expect=2e-27]; ENSG00000101280, ANGPT4, angiopoietin 4, [Score=111, Expect=4e-27]} {Mouse: ENSMUSG00000026841, Fibcd1, fibrinogen C domain containing 1, [Score=114, Expect=2e-28]; ENSMUSG00000026835, Fcnb, ficolin B, [Score=110, Expect=1e-27]} {Dmel: FBgn0003326, sca, scabrous, [Score=108, Expect=3e-26]} {Celegans: WBGene00020516, T15B7.1, [Score=52.8, Expect=1e-07]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=107, Expect=4e-26]} {RNA1310_36897.1} {RNA815_29373} |
7. | MligTC455_04009 | 478 | 9.96 | Mlig455_001797 | Neo: - Age: - |
DGKQ | 0.96 | - | - | - | - | 0.960 | - | Mlig455_001797 {REF} {Length: 5042} {TRANSSPLICED} {Pfam: Diacylglycerol kinase accessory domain [PF00609.21, score=185.2]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=99.3]; Diacylglycerol kinase catalytic domain [PF00781.26, score=79.4]; Ras association (RalGDS/AF-6) domain [PF00788.25, score=38.7]} {Human: ENSG00000145214, DGKQ, diacylglycerol kinase theta, [RH, Score=650, Expect=0.0]} {Mouse: ENSMUSG00000004815, Dgkq, diacylglycerol kinase, theta, [RH, Score=667, Expect=0.0]} {Dmel: FBgn0051140, CG31140, [Score=978, Expect=0.0]} {Celegans: WBGene00000958, dgk-1, Diacylglycerol kinase, [Score=809, Expect=0.0]} {Smed: dd_Smed_v6_7792_0_5, dd_Smed_v6_7792_0_5, [RH, Score=1024, Expect=0.0]} {RNA1509_8388} {RNA1310_12564} {RNA815_1076.1} |
8. | MligTC455_37343 | 240 | 4.99 | Mlig455_024086 | Neo: - Age: Up-Down-Up Region-enriched R8: 2.659/0.04266 |
0.955 | - | - | - | - | - | 0.955 | Mlig455_024086 {REF} {Length: 4209} {RNA1509_36528, RNA1509_59718} {RNA1310_12514, RNA1509_36528, RNA1509_59718} {RNA1509_36528, RNA1509_59718, RNA815_21020} | |
9. | MligTC455_22833 | 26 | 0.53 | Mlig455_032676, Mlig455_053220 | Neo: - Age: - |
0.954 | - | - | - | - | 0.954 | - | Mlig455_032676 {REF} {Length: 2338} {RNA1509_13897} {RNA1310_37548} {RNA815_18436} Mlig455_053220 {REF} {Length: 1918} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=44.0]} {Smed: dd_Smed_v6_21592_0_1, dd_Smed_v6_21592_0_1, [RH, Score=59.7, Expect=1e-09]} {RNA1509_37997} {RNA1310_32023} {RNA815_1077} |
|
10. | MligTC455_29323 | 239 | 4.98 | Mlig455_053598 | Neo: - Age: - |
NOTCH4 | 0.954 | - | - | - | - | 0.954 | - | Mlig455_053598 {REF} {Length: 4886} {Pfam: EGF-like domain [PF00008.29, score=147.1]; Human growth factor-like EGF [PF12661.9, score=87.2]; Ankyrin repeats (3 copies) [PF12796.9, score=85.5]; Ankyrin repeats (many copies) [PF13857.8, score=77.4]; Ankyrin repeat [PF00023.32, score=64.8]; Ankyrin repeats (many copies) [PF13637.8, score=64.3]; Ankyrin repeat [PF13606.8, score=59.4]; LNR domain [PF00066.19, score=53.5]; EGF-like domain [PF07974.15, score=44.0]; Calcium-binding EGF domain [PF07645.17, score=31.7]} {Human: ENSG00000235396, NOTCH4, notch 4, [Score=312, Expect=1e-87]; ENSG00000206312, NOTCH4, notch 4, [Score=312, Expect=1e-87]; ENSG00000234876, NOTCH4, notch 4, [Score=311, Expect=1e-87]; ENSG00000223355, NOTCH4, notch 4, [Score=311, Expect=1e-87]; ENSG00000204301, NOTCH4, notch 4, [Score=311, Expect=1e-87]; ENSG00000232339, NOTCH4, notch 4, [Score=311, Expect=1e-87]; ENSG00000134250, NOTCH2, notch 2, [Score=309, Expect=1e-86]; ENSG00000238196, NOTCH4, notch 4, [Score=297, Expect=1e-84]} {Mouse: ENSMUSG00000027878, Notch2, notch 2, [Score=349, Expect=5e-100]} {Dmel: FBgn0004647, N, Notch, [Score=332, Expect=1e-94]} {Celegans: WBGene00003001, lin-12, [Score=240, Expect=6e-65]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [Score=239, Expect=2e-64]} {RNA1509_20447, RNA1509_57909} {RNA1310_1718.1, RNA1509_57909} {RNA1509_57909, RNA815_12429} |
11. | MligTC455_16966 | 2476 | 51.58 | Mlig455_018048 | Neo: - Age: logFC(26M/2M)=0.262 |
FLOT1 | 0.952 | - | - | - | - | - | 0.952 | Mlig455_018048 {REF} {Length: 2585} {Pfam: Flotillin [PF15975.7, score=25.8]} {Human: ENSG00000224740, FLOT1, flotillin 1, [Score=361, Expect=2e-124]; ENSG00000232280, FLOT1, flotillin 1, [Score=360, Expect=2e-123]; ENSG00000206379, FLOT1, flotillin 1, [Score=360, Expect=2e-123]; ENSG00000137312, FLOT1, flotillin 1, [Score=360, Expect=2e-123]; ENSG00000206480, FLOT1, flotillin 1, [Score=360, Expect=2e-123]; ENSG00000230143, FLOT1, flotillin 1, [Score=360, Expect=2e-123]} {Mouse: ENSMUSG00000059714, Flot1, flotillin 1, [Score=360, Expect=3e-123]} {Dmel: FBgn0024754, Flo1, Flotillin 1, [Score=363, Expect=1e-124]} {Smed: dd_Smed_v6_1637_0_1, dd_Smed_v6_1637_0_1, [Score=386, Expect=6e-134]} {RNA1509_1308} {RNA1310_22496} {RNA815_8769} |
12. | MligTC455_39054 | 393 | 8.19 | Mlig455_027098 | Neo: - Age: - |
0.952 | - | - | - | - | 0.952 | - | Mlig455_027098 {REF} {Length: 3225} {TRANSSPLICED} {RNA1509_25890} {RNA1310_34328} {RNA815_25249} | |
13. | MligTC455_32691 | 346 | 7.2 | Mlig455_064692 | Neo: - Age: - |
0.951 | - | - | - | - | 0.951 | - | Mlig455_064692 {REF} {Length: 1120} {Pfam: Domain of unknown function (DUF4472) [PF14739.8, score=20.1]} {Mouse: ENSMUSG00000025272, Tro, trophinin, [Score=70.9, Expect=1e-15]} {RNA1310_132693} {RNA815_26782} | |
14. | MligTC455_23428 | 668 | 13.92 | Mlig455_031275 | Neo: - Age: - |
ALKBH3 | 0.95 | - | - | - | - | 0.950 | - | Mlig455_031275 {REF} {Length: 3723} {TRANSSPLICED} {Pfam: 2OG-Fe(II) oxygenase superfamily [PF13532.8, score=112.8]} {Human: ENSG00000166199, ALKBH3, alkB homolog 3, alpha-ketoglutaratedependent dioxygenase, [RH, Score=189, Expect=9e-56]} {Mouse: ENSMUSG00000040174, Alkbh3, alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase, [RH, Score=183, Expect=2e-53]} {Smed: dd_Smed_v6_7441_0_1, dd_Smed_v6_7441_0_1, [RH, Score=163, Expect=3e-46]} {RNA1509_12177, RNA1509_26961} {RNA1310_16694, RNA1509_12177, RNA1509_26961} {RNA1509_12177, RNA1509_26961, RNA815_12533} |
15. | MligTC455_35178 | 1644 | 34.24 | Mlig455_030126, Mlig455_030191 | Neo: - Age: - |
RFX3 | 0.95 | - | - | - | - | 0.950 | - | Mlig455_030126 {REF} {Length: 4821} {Pfam: RFX DNA-binding domain [PF02257.17, score=114.6]} {Human: ENSG00000080298, RFX3, regulatory factor X3, [Score=553, Expect=0.0]; ENSG00000132005, RFX1, regulatory factor X1, [Score=528, Expect=3e-173]} {Mouse: ENSMUSG00000040929, Rfx3, regulatory factor X, 3 (influences HLA class II expression), [Score=566, Expect=0.0]} {Dmel: FBgn0020379, Rfx, [RH, Score=513, Expect=6e-169]} {Celegans: WBGene00000914, daf-19, RFX-like transcription factor daf-19, [RH, Score=373, Expect=2e-116]} {Smed: dd_Smed_v6_5636_0_1, dd_Smed_v6_5636_0_1, [RH, Score=552, Expect=0.0]} {RNA1509_14505} {RNA1310_2070.1, RNA1509_14505} {RNA1509_14505, RNA815_7519.1} Mlig455_030191 {REF} {Length: 3987} {TRANSSPLICED} {Pfam: RFX DNA-binding domain [PF02257.17, score=114.6]} {Human: ENSG00000080298, RFX3, regulatory factor X3, [Score=554, Expect=0.0]} {Mouse: ENSMUSG00000040929, Rfx3, regulatory factor X, 3 (influences HLA class II expression), [Score=566, Expect=0.0]} {Dmel: FBgn0020379, Rfx, [Score=511, Expect=2e-168]} {Celegans: WBGene00000914, daf-19, RFX-like transcription factor daf-19, [Score=373, Expect=2e-118]} {Smed: dd_Smed_v6_5636_0_1, dd_Smed_v6_5636_0_1, [RH, Score=552, Expect=0.0]} {RNA1509_14505, RNA1509_17242, RNA1509_31559, RNA1509_41210} {RNA1310_2558, RNA1509_17242, RNA1509_31559, RNA1509_41210} {RNA1509_17242, RNA1509_31559, RNA1509_41210, RNA815_12186} |