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Results for MligTC455_34533

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_34533 317 6.61 Mlig455_043101, Mlig455_043112

Neo: -

Age: -

CASP2

Mlig455_043101 {REF} {Length: 3060} {TRANSSPLICED} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=48.1, Expect=5e-06]} {RNA1509_8195} {RNA1310_3988} {RNA815_1585}

Mlig455_043112 {REF} {Length: 3062} {TRANSSPLICED} {Pfam: Caspase domain [PF00656.24, score=108.6]} {Human: ENSG00000106144, CASP2, caspase 2, [Score=84.7, Expect=1e-16]} {Mouse: ENSMUSG00000029863, Casp2, caspase 2, [Score=84.7, Expect=7e-17]} {Dmel: FBgn0028381, Decay, Death executioner caspase related to Apopain/Yama, [Score=90.9, Expect=1e-19]} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=91.3, Expect=4e-20]} {Smed: dd_Smed_v6_3121_1_1, dd_Smed_v6_3121_1_1, [Score=73.9, Expect=2e-14]} {RNA1509_8195} {RNA1310_3988, RNA1509_8195} {RNA1509_8195, RNA815_1585}

Cumulative graph for MligTC455_34533

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.027 3.097 0.98787 1.00000
RegionR2 1.602 3.097 0.05654 0.28545
RegionR3 0.723 3.097 0.29860 0.84124
RegionR4 -0.875 3.097 0.35314 0.67511
RegionR5 -0.374 3.097 0.60690 0.96417
RegionR6 -0.755 3.097 0.36343 0.94548
RegionR7 -0.567 3.097 0.53126 1.00000
RegionR8 0.22 3.097 0.81384 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -5.953 3.097 0.24152 0.96582
RegenerationR2 1.114 3.097 0.20795 0.65595
RegenerationR3 0.661 3.097 0.49095 0.85425
RegenerationR4 1.593 3.097 0.14466 0.57013
RegenerationR5 0.427 3.097 0.66042 0.93639
RegenerationR6 1.13 3.097 0.27638 0.62534
RegenerationBL 0.968 3.097 0.33250 0.69921
RegenerationTP 0.857 3.097 0.42014 0.84432


Genes with expression patterns similar to MligTC455_34533

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_34533 317 6.61 Mlig455_043101, Mlig455_043112

Neo: -

Age: -

CASP2 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_043101 {REF} {Length: 3060} {TRANSSPLICED} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=48.1, Expect=5e-06]} {RNA1509_8195} {RNA1310_3988} {RNA815_1585}

Mlig455_043112 {REF} {Length: 3062} {TRANSSPLICED} {Pfam: Caspase domain [PF00656.24, score=108.6]} {Human: ENSG00000106144, CASP2, caspase 2, [Score=84.7, Expect=1e-16]} {Mouse: ENSMUSG00000029863, Casp2, caspase 2, [Score=84.7, Expect=7e-17]} {Dmel: FBgn0028381, Decay, Death executioner caspase related to Apopain/Yama, [Score=90.9, Expect=1e-19]} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=91.3, Expect=4e-20]} {Smed: dd_Smed_v6_3121_1_1, dd_Smed_v6_3121_1_1, [Score=73.9, Expect=2e-14]} {RNA1509_8195} {RNA1310_3988, RNA1509_8195} {RNA1509_8195, RNA815_1585}
2. MligTC455_45021 381 7.95 Mlig455_046686

Neo: -

Age: Down-Up-Up

Region-enriched R2: 3.428/0.03156

AVP 2.765 0.904 - - - 0.958 0.903 Mlig455_046686 {REF} {Length: 1388} {Pfam: Neurohypophysial hormones, C-terminal Domain [PF00184.19, score=36.2]} {Human: ENSG00000101200, AVP, arginine vasopressin, [Score=54.3, Expect=2e-09]} {Mouse: ENSMUSG00000037727, Avp, arginine vasopressin, [Score=53.1, Expect=3e-09]} {RNA1509_50574} {RNA1310_38922} {RNA815_23813}
3. MligTC455_29168 95 1.99 Mlig455_001005

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.838/0.04040

DNAH5 2.741 0.905 - - - 0.984 0.852 Mlig455_001005 {REF} {Length: 14882} {Pfam: Dynein heavy chain, N-terminal region 1 [PF08385.14, score=578.4]; Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=466.5]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=431.3]; Dynein heavy chain C-terminal domain [PF18199.3, score=314.7]; P-loop containing dynein motor region D4 [PF12780.9, score=302.4]; ATP-binding dynein motor region [PF12781.9, score=290.8]; P-loop containing dynein motor region [PF12775.9, score=229.7]; Dynein heavy chain AAA lid domain [PF18198.3, score=179.1]; Microtubule-binding stalk of dynein motor [PF12777.9, score=143.2]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=121.5]; AAA domain (dynein-related subfamily) [PF07728.16, score=75.6]; Dynein heavy chain AAA lid domain [PF17852.3, score=70.7]; AAA+ lid domain [PF17857.3, score=60.9]; AAA ATPase domain [PF13191.8, score=22.0]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=21.4]; P-loop containing region of AAA domain [PF13555.8, score=20.3]} {Human: ENSG00000039139, DNAH5, dynein axonemal heavy chain 5, [RH, Score=6260, Expect=0.0]} {Mouse: ENSMUSG00000022262, Dnah5, dynein, axonemal, heavy chain 5, [RH, Score=6234, Expect=0.0]} {Dmel: FBgn0037726, CG9492, [RH, Score=5093, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=1290, Expect=0.0]} {Smed: dd_Smed_v6_4569_0_1, dd_Smed_v6_4569_0_1, [RH, Score=6941, Expect=0.0]} {RNA1509_51275} {RNA1310_408, RNA1509_51275} {RNA1509_51275, RNA815_44.1}
4. MligTC455_50665 48 0.99 Mlig455_032812

Neo: -

Age: -

2.716 0.913 - - - 0.960 0.843 Mlig455_032812 {REF} {Length: 1550} {Pfam: Glycine rich protein [PF12810.9, score=23.7]} {RNA1310_48243.1} {RNA815_30313.2}
5. MligTC455_53339 361 7.52 Mlig455_044792, Mlig455_044816, Mlig455_055565

Neo: -

Age: -

Region-enriched R2: 2.402/0.04439

DMBT1 2.654 - 0.797 - - 0.971 0.886

Mlig455_044792 {REF} {Length: 2555} {Pfam: Zona pellucida-like domain [PF00100.25, score=90.4]; Scavenger receptor cysteine-rich domain [PF00530.20, score=77.7]} {Human: ENSG00000187908, DMBT1, deleted in malignant brain tumors 1, [Score=67.0, Expect=8e-11]} {Mouse: ENSMUSG00000008845, Cd163, CD163 antigen, [Score=58.2, Expect=3e-08]} {Smed: dd_Smed_v6_8185_0_1, dd_Smed_v6_8185_0_1, [Score=73.9, Expect=9e-14]} {RNA1509_36885} {RNA1310_10008} {RNA815_6134}

Mlig455_044816 {REF} {Length: 2732} {Pfam: Zona pellucida-like domain [PF00100.25, score=89.0]; Scavenger receptor cysteine-rich domain [PF00530.20, score=78.1]} {Human: ENSG00000187908, DMBT1, deleted in malignant brain tumors 1, [Score=67.0, Expect=9e-11]} {Mouse: ENSMUSG00000008845, Cd163, CD163 antigen, [Score=56.6, Expect=8e-08]} {Smed: dd_Smed_v6_8185_0_1, dd_Smed_v6_8185_0_1, [Score=73.6, Expect=1e-13]} {RNA1509_36885} {RNA1310_10008, RNA1509_36885} {RNA1509_36885, RNA815_6134}

Mlig455_055565 {REF} {Length: 2284} {Pfam: Scavenger receptor cysteine-rich domain [PF00530.20, score=79.3]; Zona pellucida-like domain [PF00100.25, score=35.8]} {Human: ENSG00000187908, DMBT1, deleted in malignant brain tumors 1, [Score=65.5, Expect=1e-10]} {Mouse: ENSMUSG00000008845, Cd163, CD163 antigen, [Score=56.6, Expect=4e-08]} {Smed: dd_Smed_v6_8185_0_1, dd_Smed_v6_8185_0_1, [Score=55.1, Expect=4e-08]} {RNA1509_36885} {RNA1310_10008} {RNA815_6134}
6. MligTC455_26091 161 3.36 Mlig455_047190

Neo: -

Age: -

Region-enriched R2: 4.521/0.00020

2.627 - 0.842 - - 0.954 0.831 Mlig455_047190 {REF} {Length: 2450} {Pfam: Lectin C-type domain [PF00059.23, score=23.6]} {RNA1509_2912} {RNA1310_27113} {RNA815_24719}
7. MligTC455_40989 801 16.68 Mlig455_016294

Neo: -

Age: logFC(26M/2M)=0.270

PKD2 2.584 0.954 0.748 - - - 0.882 Mlig455_016294 {REF} {Length: 3179} {Pfam: Polycystin cation channel [PF08016.14, score=486.5]; Ion transport protein [PF00520.33, score=90.3]; EF hand [PF00036.34, score=23.7]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=718, Expect=0.0]; ENSG00000107593, PKD2L1, polycystin 2 like 1, transient receptor potential cation channel, [RH, Score=712, Expect=0.0]} {Mouse: ENSMUSG00000037578, Pkd2l1, polycystic kidney disease 2-like 1, [RH, Score=704, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [RH, Score=310, Expect=2e-91]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [RH, Score=370, Expect=7e-116]} {Smed: dd_Smed_v6_13327_0_1, dd_Smed_v6_13327_0_1, [RH, Score=743, Expect=0.0]} {RNA1509_14023, RNA1509_24240} {RNA1310_4836.1, RNA1509_14023, RNA1509_24240} {RNA1509_14023, RNA1509_24240, RNA815_4677}
8. MligTC455_32338 2035 42.39 Mlig455_029302, Mlig455_029324, Mlig455_058867

Neo: -

Age: -

ZMYND8 2.541 0.743 - - 0.840 - 0.958

Mlig455_029302 {REF} {Length: 3403} {Pfam: MYND finger [PF01753.20, score=19.3]} {Human: ENSG00000101040, ZMYND8, zinc finger MYND-type containing 8, [Score=127, Expect=2e-30]} {Mouse: ENSMUSG00000039671, Zmynd8, zinc finger, MYND-type containing 8, [Score=130, Expect=1e-31]} {Dmel: FBgn0039863, CG1815, [Score=101, Expect=2e-22]} {Celegans: WBGene00017757, bra-2, BMP Receptor Associated protein family, [Score=72.0, Expect=3e-14]} {Smed: dd_Smed_v6_8799_0_2, dd_Smed_v6_8799_0_2, [RH, Score=86.7, Expect=3e-19]} {RNA1509_23732} {RNA1310_8252.1} {RNA815_15296}

Mlig455_029324 {REF} {Length: 3062} {Pfam: MYND finger [PF01753.20, score=19.3]} {Human: ENSG00000101040, ZMYND8, zinc finger MYND-type containing 8, [Score=127, Expect=2e-30]} {Mouse: ENSMUSG00000039671, Zmynd8, zinc finger, MYND-type containing 8, [Score=130, Expect=2e-31]} {Dmel: FBgn0039863, CG1815, [Score=101, Expect=3e-22]} {Celegans: WBGene00017757, bra-2, BMP Receptor Associated protein family, [Score=71.6, Expect=3e-14]} {Smed: dd_Smed_v6_8799_0_2, dd_Smed_v6_8799_0_2, [RH, Score=86.7, Expect=3e-19]} {RNA1509_23732, RNA1509_54921} {RNA1310_8252.1, RNA1509_23732, RNA1509_54921} {RNA1509_23732, RNA1509_54921, RNA815_15296}

Mlig455_058867 {REF} {Length: 3248} {Pfam: MYND finger [PF01753.20, score=19.3]} {Human: ENSG00000101040, ZMYND8, zinc finger MYND-type containing 8, [Score=126, Expect=3e-30]} {Mouse: ENSMUSG00000039671, Zmynd8, zinc finger, MYND-type containing 8, [Score=129, Expect=3e-31]} {Dmel: FBgn0039863, CG1815, [Score=101, Expect=3e-22]} {Celegans: WBGene00017757, bra-2, BMP Receptor Associated protein family, [Score=70.9, Expect=7e-14]} {Smed: dd_Smed_v6_8799_0_2, dd_Smed_v6_8799_0_2, [RH, Score=85.1, Expect=1e-18]} {RNA1509_23732} {RNA1310_8252.1} {RNA815_15296}
9. MligTC455_21668 84 1.74 Mlig455_024837

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=1.324

PPP3R1 2.538 - 0.798 - - 0.959 0.781 Mlig455_024837 {REF} {Length: 1650} {Pfam: EF hand [PF00036.34, score=92.6]; EF-hand domain pair [PF13499.8, score=86.6]; EF-hand domain [PF13405.8, score=74.3]; EF hand [PF13202.8, score=72.6]; EF-hand domain pair [PF13833.8, score=65.7]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=30.2]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=27.0]; EF-hand domain [PF14658.8, score=21.7]} {Human: ENSG00000221823, PPP3R1, protein phosphatase 3 regulatory subunit B, alpha, [RH, Score=289, Expect=5e-101]} {Mouse: ENSMUSG00000033953, Ppp3r1, protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I), [RH, Score=289, Expect=3e-101]} {Dmel: FBgn0010014, CanB, Calcineurin B, [RH, Score=282, Expect=1e-98]} {Celegans: WBGene00000554, cnb-1, Protein phosphatase 2B regulatory subunit cnb-1, [RH, Score=272, Expect=7e-95]} {Smed: dd_Smed_v6_5589_0_1, dd_Smed_v6_5589_0_1, [RH, Score=281, Expect=1e-98]} {RNA1509_14613} {RNA1310_16848.1} {RNA815_6272}
10. MligTC455_50052 580 12.08 Mlig455_026909, Mlig455_027066

Neo: -

Age: -

Region-specific R2: 2.801

Region-enriched R2: 1.805/0.00804

STOM 2.523 - - - 0.789 0.967 0.767

Mlig455_026909 {REF} {Length: 1737} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=110.6]; SPFH domain-Band 7 family [PF13421.8, score=19.9]} {Human: ENSG00000148175, STOM, stomatin, [RH, Score=358, Expect=4e-124]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [RH, Score=355, Expect=4e-123]} {Dmel: FBgn0260657, CG42540, [Score=361, Expect=4e-124]} {Celegans: WBGene00003166, mec-2, Mechanosensory protein 2, [RH, Score=380, Expect=8e-132]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [RH, Score=439, Expect=8e-157]} {RNA1509_53478} {RNA1310_8094.2} {RNA815_8739}

Mlig455_027066 {REF} {Length: 3038} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=105.6]} {Human: ENSG00000148175, STOM, stomatin, [Score=345, Expect=5e-119]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [Score=342, Expect=6e-118]} {Dmel: FBgn0260657, CG42540, [Score=349, Expect=3e-119]} {Celegans: WBGene00003166, mec-2, Mechanosensory protein 2, [Score=369, Expect=4e-127]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [RH, Score=427, Expect=9e-152]} {RNA1509_53478} {RNA1310_8094.2} {RNA815_8739}
11. MligTC455_50750 137 2.86 Mlig455_004587

Neo: -

Age: -

GNB5 2.453 - 0.793 - - 0.710 0.950 Mlig455_004587 {REF} {Length: 6245} {Pfam: WD domain, G-beta repeat [PF00400.34, score=96.6]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=48.4]; Eukaryotic translation initiation factor eIF2A [PF08662.13, score=26.3]; WD40-like domain [PF17005.7, score=24.1]} {Human: ENSG00000069966, GNB5, G protein subunit beta 5, [Score=411, Expect=2e-144]} {Mouse: ENSMUSG00000032192, Gnb5, guanine nucleotide binding protein (G protein), beta 5, [Score=412, Expect=9e-145]} {Dmel: FBgn0030011, Gbeta5, [Score=430, Expect=4e-152]} {Celegans: WBGene00001680, gpb-2, Guanine nucleotide-binding protein subunit beta-2, [Score=402, Expect=6e-141]} {Smed: dd_Smed_v6_10481_0_1, dd_Smed_v6_10481_0_1, [Score=476, Expect=9e-171]} {RNA1509_51468} {RNA1310_13844.1} {RNA815_14582}
12. MligTC455_46155 116 2.42 Mlig455_027239

Neo: -

Age: -

Region-enriched R2: 4.163/0.03818

GRK3 1.903 - - - - 0.935 0.968 Mlig455_027239 {REF} {Length: 2919} {Pfam: Protein kinase domain [PF00069.27, score=226.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=100.5]; Regulator of G protein signaling domain [PF00615.21, score=48.3]} {Human: ENSG00000100077, GRK3, G protein-coupled receptor kinase 3, [Score=845, Expect=0.0]; ENSG00000173020, GRK2, G protein-coupled receptor kinase 2, [Score=838, Expect=0.0]} {Mouse: ENSMUSG00000042249, Grk3, G protein-coupled receptor kinase 3, [Score=838, Expect=0.0]; ENSMUSG00000024858, Grk2, G protein-coupled receptor kinase 2, [Score=838, Expect=0.0]} {Dmel: FBgn0260798, Gprk1, G protein-coupled receptor kinase 1, [Score=842, Expect=0.0]} {Celegans: WBGene00001709, grk-2, G protein-coupled receptor kinase 2, [Score=819, Expect=0.0]} {Smed: dd_Smed_v6_6480_0_1, dd_Smed_v6_6480_0_1, [Score=949, Expect=0.0]} {RNA1509_7002} {RNA1310_16658} {RNA815_28070}
13. MligTC455_22469 37 0.77 Mlig455_052705

Neo: -

Age: logFC(26M/2M)=-1.003

GUK1 1.854 0.956 - - - - 0.898 Mlig455_052705 {REF} {Length: 1833} {Pfam: Guanylate kinase [PF00625.23, score=207.7]; AAA domain [PF13671.8, score=35.1]; 50S ribosome-binding GTPase [PF01926.25, score=28.4]; AAA domain [PF13238.8, score=26.9]; ABC transporter [PF00005.29, score=24.3]; AAA ATPase domain [PF13191.8, score=24.0]; AAA domain [PF13401.8, score=23.0]; P-loop containing region of AAA domain [PF13555.8, score=21.3]; RsgA GTPase [PF03193.18, score=20.4]; AAA domain, putative AbiEii toxin, Type IV TA system [PF13304.8, score=19.0]} {Human: ENSG00000143774, GUK1, guanylate kinase 1, [RH, Score=230, Expect=4e-77]} {Mouse: ENSMUSG00000020444, Guk1, guanylate kinase 1, [RH, Score=228, Expect=2e-76]} {Dmel: FBgn0036099, CG11811, [RH, Score=202, Expect=9e-66]} {Celegans: WBGene00020190, guk-1, GUanylate Kinase, [RH, Score=195, Expect=2e-63]} {Smed: dd_Smed_v6_4875_0_1, dd_Smed_v6_4875_0_1, [RH, Score=225, Expect=2e-75]} {RNA1509_30404} {RNA1310_39734} {RNA815_22943.1}
14. MligTC455_46564 403 8.4 Mlig455_040238

Neo: -

Age: -

1.842 - - - - 0.886 0.956 Mlig455_040238 {REF} {Length: 3013} {RNA1509_9486} {RNA1310_9854} {RNA815_15545}
15. MligTC455_47420 218 4.54 Mlig455_017159, Mlig455_048110

Neo: -

Age: -

Region-specific R2: 6.469

Region-enriched R2: 5.851/0.00135

1.842 - - - - 0.952 0.890

Mlig455_017159 {REF} {Length: 1062} {RNA1509_35349} {RNA1310_81586}

Mlig455_048110 {REF} {Length: 527} {RNA1310_81586}
16. MligTC455_31273 40 0.83 Mlig455_017570

Neo: -

Age: -

JMJD6 1.835 - - - - 0.950 0.885 Mlig455_017570 {REF} {Length: 2550} {Pfam: Cupin-like domain [PF13621.8, score=84.8]; JmjC domain, hydroxylase [PF02373.24, score=41.9]; Cupin superfamily protein [PF08007.14, score=22.1]} {Human: ENSG00000070495, JMJD6, jumonji domain containing 6, arginine demethylase and lysine hydroxylase, [Score=81.6, Expect=3e-16]} {Mouse: ENSMUSG00000056962, Jmjd6, jumonji domain containing 6, [Score=79.0, Expect=2e-15]} {Dmel: FBgn0038948, PSR, phosphatidylserine receptor, [Score=77.8, Expect=3e-15]} {Celegans: WBGene00004205, psr-1, Bifunctional arginine demethylase and lysyl-hydroxylase psr-1, [Score=88.6, Expect=6e-19]} {Smed: dd_Smed_v6_12267_0_1, dd_Smed_v6_12267_0_1, [RH, Score=327, Expect=7e-108]} {RNA1310_17984} {RNA815_15470}
17. MligTC455_00245 15 0.32 Mlig455_040042

Neo: -

Age: -

GPR17 1.829 - - - - 0.955 0.874 Mlig455_040042 {REF} {Length: 1332} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=36.0]} {Human: ENSG00000144230, GPR17, G protein-coupled receptor 17, [Score=48.9, Expect=6e-06]} {Smed: dd_Smed_v6_61185_0_1, dd_Smed_v6_61185_0_1, [Score=70.9, Expect=1e-14]} {RNA1310_142905}
18. MligTC455_53435 190 3.96 Mlig455_045425, Mlig455_065748

Neo: -

Age: -

Region-enriched R2: 4.111/0.00023

SYT9 1.829 - - - - 0.959 0.870

Mlig455_045425 {REF} {Length: 2615} {RNA1509_46689} {RNA1310_15031, RNA1509_46689} {RNA1509_46689, RNA815_18779.1}

Mlig455_065748 {REF} {Length: 3143} {Pfam: C2 domain [PF00168.32, score=116.1]} {Human: ENSG00000170743, SYT9, synaptotagmin 9, [Score=162, Expect=4e-42]; ENSG00000213023, SYT3, synaptotagmin 3, [Score=157, Expect=5e-40]} {Mouse: ENSMUSG00000062542, Syt9, synaptotagmin IX, [Score=162, Expect=3e-42]; ENSMUSG00000030731, Syt3, synaptotagmin III, [Score=156, Expect=1e-39]} {Dmel: FBgn0261089, Sytalpha, Synaptotagmin alpha, [RH, Score=197, Expect=1e-54]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=144, Expect=8e-37]} {Smed: dd_Smed_v6_6730_0_1, dd_Smed_v6_6730_0_1, [Score=155, Expect=5e-41]} {RNA1509_46689} {RNA1310_15031} {RNA815_18779.1}
19. MligTC455_39218 2348 48.93 Mlig455_041424, Mlig455_061374, Mlig455_061402

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.484

Region-enriched R8: 1.418/0.00334

1.824 - - - 0.955 0.869 -

Mlig455_041424 {REF} {Length: 2036} {RNA1509_20247} {RNA1310_14766.1} {RNA815_5556.1}

Mlig455_061374 {REF} {Length: 2145} {RNA1509_20247} {RNA1310_14766.1} {RNA815_5556.1}

Mlig455_061402 {REF} {Length: 2213} {RNA1509_42364, RNA1509_44881} {RNA1310_14766.1, RNA1509_42364} {RNA1509_42364, RNA815_5556.1}
20. MligTC455_11558 137 2.85 Mlig455_058259

Neo: -

Age: logFC(26M/2M)=-0.792

1.821 - - - - 0.955 0.866 Mlig455_058259 {REF} {Length: 896} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=19.9]} {RNA1509_58923} {RNA1310_41706, RNA1509_58923} {RNA1509_58923, RNA815_20876}
21. MligTC455_27330 2939 61.23 Mlig455_029694

Neo: -

Age: -

Region-specific R2: 5.698

Region-enriched R2: 5.201/0.00000

Regeneration-downregulated R2: -3.996

Regeneration-depleted R2: -3.996

1.795 - 0.843 - - 0.952 - Mlig455_029694 {REF} {Length: 2374} {TRANSSPLICED} {RNA1509_22512} {RNA1310_16498, RNA1509_22512} {RNA1509_22512, RNA815_17345}
22. MligTC455_41540 190 3.96 Mlig455_060056

Neo: -

Age: -

Region-enriched R2: 6.605/0.00196

GLUL 1.795 0.952 - - - - 0.843 Mlig455_060056 {REF} {Length: 1355} {Pfam: Glutamine synthetase, catalytic domain [PF00120.26, score=57.3]; Glutamine synthetase, beta-Grasp domain [PF03951.21, score=47.5]} {Human: ENSG00000135821, GLUL, glutamate-ammonia ligase, [RH, Score=511, Expect=1e-180]} {Mouse: ENSMUSG00000026473, Glul, glutamate-ammonia ligase (glutamine synthetase), [RH, Score=511, Expect=0.0]} {Dmel: FBgn0001145, Gs2, Glutamine synthetase 2, [RH, Score=511, Expect=0.0]} {Celegans: WBGene00001604, gln-3, Glutamine synthetase, [RH, Score=515, Expect=0.0]} {Smed: dd_Smed_v6_896_0_1, dd_Smed_v6_896_0_1, [RH, Score=545, Expect=0.0]} {RNA1509_47000} {RNA1310_22329.2} {RNA815_4116.6}
23. MligTC455_53609 596 12.41 Mlig455_044296

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.314

Region-enriched R2: 5.752/0.03997

1.795 - 0.824 - - 0.971 - Mlig455_044296 {REF} {Length: 1128} {RNA1509_40777} {RNA1310_31452.1} {RNA815_12344.1}
24. MligTC455_27331 2162 45.05 Mlig455_034840

Neo: -

Age: logFC(26M/2M)=-0.500

Region-specific R2: 5.384

Region-enriched R2: 4.962/0.00000

Regeneration-downregulated R2: -3.612

Regeneration-depleted R2: -3.612

1.79 - 0.837 - - 0.953 - Mlig455_034840 {REF} {Length: 2399} {TRANSSPLICED} {RNA1509_22512, RNA1509_3017, RNA1509_47207} {RNA1310_16498, RNA1509_3017, RNA1509_47207} {RNA1509_3017, RNA1509_47207, RNA815_17345}
25. MligTC455_36111 458 9.53 Mlig455_043348

Neo: -

Age: logFC(26M/2M)=-0.240

CCDC170 1.788 0.973 - - - - 0.815 Mlig455_043348 {REF} {Length: 3633} {Pfam: Protein of unknown function (DUF3450) [PF11932.10, score=30.4]} {Human: ENSG00000120262, CCDC170, coiled-coil domain containing 170, [Score=136, Expect=9e-33]} {Mouse: ENSMUSG00000019767, Ccdc170, coiled-coil domain containing 170, [Score=150, Expect=2e-37]} {Dmel: FBgn0263079, CG43338, [Score=84.3, Expect=2e-16]} {Smed: dd_Smed_v6_7066_0_1, dd_Smed_v6_7066_0_1, [Score=192, Expect=7e-52]} {RNA1509_13555, RNA1509_26608, RNA1509_28561, RNA1509_45523, RNA1509_60067} {RNA1310_10671.1, RNA1509_13555, RNA1509_26608, RNA1509_28561, RNA1509_45523, RNA1509_60067} {RNA1509_13555, RNA1509_26608, RNA1509_28561, RNA1509_45523, RNA1509_60067, RNA815_3132}
26. MligTC455_42969 549 11.44 Mlig455_016709

Neo: -

Age: Down-Up-Down

Region-enriched R4: 1.336/0.03654

CCDC105 1.777 - 0.820 - - - 0.957 Mlig455_016709 {REF} {Length: 2752} {Pfam: Tektin family [PF03148.16, score=75.8]} {Human: ENSG00000160994, CCDC105, coiled-coil domain containing 105, [RH, Score=118, Expect=1e-28]} {Mouse: ENSMUSG00000078442, Ccdc105, coiled-coil domain containing 105, [RH, Score=129, Expect=1e-32]} {Smed: dd_Smed_v6_14773_0_1, dd_Smed_v6_14773_0_1, [RH, Score=224, Expect=4e-69]} {RNA1509_16464, RNA1509_59777} {RNA1310_6775.2, RNA1509_16464, RNA1509_59777} {RNA1509_16464, RNA1509_59777, RNA815_2314.1}
27. MligTC455_19465 216 4.5 Mlig455_011567

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.898

Region-enriched R2: 2.709/0.02014

LRRC69 1.772 0.973 0.799 - - - - Mlig455_011567 {REF} {Length: 2449} {TRANSSPLICED} {Pfam: Leucine rich repeat [PF13855.8, score=92.7]; Leucine Rich repeats (2 copies) [PF12799.9, score=80.1]; Leucine Rich repeat [PF13516.8, score=33.3]; Leucine Rich Repeat [PF00560.35, score=27.4]} {Human: ENSG00000214954, LRRC69, leucine rich repeat containing 69, [RH, Score=198, Expect=7e-60]} {Mouse: ENSMUSG00000023151, Lrrc69, leucine rich repeat containing 69, [RH, Score=218, Expect=1e-67]} {Dmel: FBgn0033984, Lap1, [Score=105, Expect=3e-24]} {Celegans: WBGene00002632, let-413, [Score=112, Expect=8e-27]} {Smed: dd_Smed_v6_14722_0_1, dd_Smed_v6_14722_0_1, [RH, Score=184, Expect=5e-56]} {RNA1509_41102} {RNA1310_3215.1} {RNA815_13052}
28. MligTC455_52092 37 0.76 Mlig455_025474

Neo: -

Age: -

1.761 - - 0.967 - 0.794 - Mlig455_025474 {REF} {Length: 901} {Pfam: Pancreatic hormone peptide [PF00159.20, score=19.5]} {RNA1509_56567} {RNA1310_46347} {RNA815_35686}
29. MligTC455_44042 460 9.59 Mlig455_021815

Neo: -

Age: logFC(26M/2M)=-0.341

CCDC181 1.758 - - - 0.808 - 0.950 Mlig455_021815 {REF} {Length: 2436} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4207) [PF13904.8, score=29.1]} {Human: ENSG00000117477, CCDC181, coiled-coil domain containing 181, [Score=70.5, Expect=2e-12]} {Mouse: ENSMUSG00000026578, Ccdc181, coiled-coil domain containing 181, [Score=72.0, Expect=4e-13]} {Smed: dd_Smed_v6_8117_0_1, dd_Smed_v6_8117_0_1, [Score=76.6, Expect=6e-15]} {RNA1509_20789} {RNA1310_10957.1, RNA1509_20789} {RNA1509_20789, RNA815_9557}
30. MligTC455_42136 34 0.7 Mlig455_024685, Mlig455_024710, Mlig455_044068

Neo: -

Age: -

1.754 - 0.798 - - 0.956 -

Mlig455_024685 {REF} {Length: 3505} {Pfam: Peptidase family M13 [PF05649.15, score=22.4]} {RNA1310_55586} {RNA815_38189}

Mlig455_024710 {REF} {Length: 3484} {RNA1310_55586} {RNA815_38189}

Mlig455_044068 {REF} {Length: 2578} {Pfam: Peptidase family M13 [PF05649.15, score=26.4]}
31. MligTC455_15369 670 13.96 Mlig455_047661

Neo: -

Age: logFC(26M/2M)=-0.336

1.74 0.757 - - - - 0.983 Mlig455_047661 {REF} {Length: 3143} {RNA1509_13243, RNA1509_19369, RNA1509_21179} {RNA1310_21541.1, RNA1509_13243, RNA1509_19369, RNA1509_21179} {RNA1509_13243, RNA1509_19369, RNA1509_21179, RNA815_16243.1}
32. MligTC455_46414 1658 34.54 Mlig455_057089

Neo: -

Age: logFC(26M/2M)=-0.221

OTOF 1.728 - 0.775 - - - 0.953 Mlig455_057089 {REF} {Length: 7426} {Pfam: C2 domain [PF00168.32, score=180.5]; FerB (NUC096) domain [PF08150.14, score=74.9]; Ferlin C-terminus [PF16165.7, score=61.5]} {Human: ENSG00000115155, OTOF, otoferlin, [Score=514, Expect=4e-149]} {Mouse: ENSMUSG00000062372, Otof, otoferlin, [Score=515, Expect=1e-149]} {Dmel: FBgn0266757, mfr, misfire, [Score=239, Expect=2e-66]} {Celegans: WBGene00001414, fer-1, Sperm vesicle fusion protein fer-1, [Score=127, Expect=7e-29]} {Smed: dd_Smed_v6_5915_0_1, dd_Smed_v6_5915_0_1, [Score=752, Expect=0.0]} {RNA1509_41457, RNA1509_6240} {RNA1310_364, RNA1509_41457} {RNA1509_41457, RNA815_373}
33. MligTC455_18333 273 5.7 Mlig455_010935

Neo: -

Age: Down-Up-Up

Region-enriched R2: 5.059/0.00307

1.705 - - - - 0.959 0.746 Mlig455_010935 {REF} {Length: 510} {RNA1310_33328.2} {RNA815_15093.1}
34. MligTC455_17901 321 6.69 Mlig455_000245

Neo: -

Age: -

LEKR1 1.702 - - - - 0.955 0.747 Mlig455_000245 {REF} {Length: 1995} {Human: ENSG00000197980, LEKR1, leucine, glutamate and lysine rich 1, [RH, Score=70.9, Expect=2e-13]} {Smed: dd_Smed_v6_16355_0_1, dd_Smed_v6_16355_0_1, [Score=59.7, Expect=4e-10]} {RNA1509_14725} {RNA1310_12283} {RNA815_17365}
35. MligTC455_31453 322 6.7 Mlig455_045794, Mlig455_063190

Neo: -

Age: -

MMD 1.691 - - - 0.735 0.956 -

Mlig455_045794 {REF} {Length: 1920} {TRANSSPLICED} {Pfam: Haemolysin-III related [PF03006.22, score=51.5]} {Human: ENSG00000108960, MMD, monocyte to macrophage differentiation associated, [Score=104, Expect=7e-27]; ENSG00000136297, MMD2, monocyte to macrophage differentiation associated 2, [Score=103, Expect=1e-26]} {Mouse: ENSMUSG00000039533, Mmd2, monocyte to macrophage differentiation-associated 2, [Score=105, Expect=3e-27]; ENSMUSG00000003948, Mmd, monocyte to macrophage differentiation-associated, [Score=104, Expect=3e-27]} {Dmel: FBgn0029935, CG4615, [Score=109, Expect=1e-28]} {Celegans: WBGene00022158, Y71G12B.23, [Score=105, Expect=2e-27]} {Smed: dd_Smed_v6_10316_0_1, dd_Smed_v6_10316_0_1, [Score=133, Expect=1e-38]} {RNA1509_50956} {RNA1310_36731} {RNA815_18300}

Mlig455_063190 {REF} {Length: 1860} {NoTransDecoderORF} {RNA1310_41509} {RNA815_22362}
36. MligTC455_44393 1005 20.93 Mlig455_036424

Neo: -

Age: logFC(26M/2M)=-0.326

SLC8A1 1.69 - - - - 0.960 0.730 Mlig455_036424 {REF} {Length: 4672} {TRANSSPLICED} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=162.1]; Calx-beta domain [PF03160.16, score=142.0]; C-terminal extension of sodium/calcium exchanger domain [PF16494.7, score=23.2]; Domain of unknown function (DUF4843) [PF16132.7, score=18.7]} {Human: ENSG00000183023, SLC8A1, solute carrier family 8 member A1, [Score=515, Expect=2e-169]; ENSG00000100678, SLC8A3, solute carrier family 8 member A3, [Score=495, Expect=6e-162]} {Mouse: ENSMUSG00000054640, Slc8a1, solute carrier family 8 (sodium/calcium exchanger), member 1, [Score=509, Expect=3e-167]; ENSMUSG00000079055, Slc8a3, solute carrier family 8 (sodium/calcium exchanger), member 3, [Score=499, Expect=8e-164]} {Dmel: FBgn0013995, Calx, Na/Ca-exchange protein, [Score=509, Expect=1e-167]} {Celegans: WBGene00003568, ncx-3, Na/Ca eXchangers, [Score=530, Expect=6e-177]} {Smed: dd_Smed_v6_3303_0_1, dd_Smed_v6_3303_0_1, [Score=489, Expect=3e-160]} {RNA1509_42629} {RNA1310_4660, RNA1509_42629} {RNA1509_42629, RNA815_12553}
37. MligTC455_48714 132 2.74 Mlig455_037041

Neo: -

Age: -

Region-enriched R2: 4.531/0.00493

1.69 - - - - 0.976 0.714 Mlig455_037041 {REF} {Length: 1099} {RNA1509_35038} {RNA1310_72135} {RNA815_37404}
38. MligTC455_23540 1720 35.83 Mlig455_001160, Mlig455_070570

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.344

Regeneration-downregulated TP: -1.716

Regeneration-depleted TP: -1.716

1.67 - - - - 0.710 0.960

Mlig455_001160 {REF} {Length: 1879} {TRANSSPLICED} {Pfam: Lectin C-type domain [PF00059.23, score=19.5]} {RNA1509_24566} {RNA1310_15626.1} {RNA815_17776}

Mlig455_070570 {REF} {Length: 2014} {TRANSSPLICED} {Pfam: Lectin C-type domain [PF00059.23, score=20.9]} {RNA1509_38964} {RNA1310_15626.1, RNA1509_38964} {RNA1509_38964, RNA815_8594}
39. MligTC455_28966 764 15.92 Mlig455_013759

Neo: -

Age: Up-Down-Down

DNAH6 1.668 0.950 - - - 0.718 - Mlig455_013759 {REF} {Length: 13376} {TRANSSPLICED} {Pfam: Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=527.6]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=446.3]; P-loop containing dynein motor region D4 [PF12780.9, score=362.2]; Dynein heavy chain C-terminal domain [PF18199.3, score=332.5]; ATP-binding dynein motor region [PF12781.9, score=309.5]; P-loop containing dynein motor region [PF12775.9, score=259.5]; Microtubule-binding stalk of dynein motor [PF12777.9, score=179.3]; Dynein heavy chain AAA lid domain [PF18198.3, score=175.3]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=149.9]; Dynein heavy chain AAA lid domain [PF17852.3, score=81.3]; AAA domain (dynein-related subfamily) [PF07728.16, score=78.3]; AAA+ lid domain [PF17857.3, score=77.2]; AAA domain [PF13401.8, score=40.0]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=39.8]; AAA ATPase domain [PF13191.8, score=36.0]; AAA domain [PF13238.8, score=33.7]; RNA helicase [PF00910.24, score=24.7]; Threonylcarbamoyl adenosine biosynthesis protein TsaE [PF02367.19, score=22.9]; Sigma-54 interaction domain [PF00158.28, score=21.2]; Type II/IV secretion system protein [PF00437.22, score=21.0]} {Human: ENSG00000115423, DNAH6, dynein axonemal heavy chain 6, [RH, Score=5172, Expect=0.0]} {Mouse: ENSMUSG00000052861, Dnah6, dynein, axonemal, heavy chain 6, [RH, Score=5138, Expect=0.0]} {Dmel: FBgn0283476, Dhc16F, Dynein heavy chain at 16F, [RH, Score=3472, Expect=0.0]} {Celegans: WBGene00000485, che-3, Cytoplasmic dynein 2 heavy chain 1, [Score=1072, Expect=0.0]} {Smed: dd_Smed_v6_14707_0_4, dd_Smed_v6_14707_0_4, [RH, Score=2881, Expect=0.0]} {RNA1509_451} {RNA1310_52.1, RNA1509_451} {RNA1509_451, RNA815_26.1}
40. MligTC455_18530 4744 98.84 Mlig455_005838

Neo: -

Age: Down-Up-Up

TSPAN16 1.667 - 0.712 - 0.955 - - Mlig455_005838 {REF} {Length: 1567} {Pfam: Tetraspanin family [PF00335.22, score=80.5]} {Human: ENSG00000130167, TSPAN16, tetraspanin 16, [Score=57.0, Expect=6e-09]} {Mouse: ENSMUSG00000028699, Tspan1, tetraspanin 1, [Score=51.2, Expect=3e-07]; ENSMUSG00000025351, Cd63, CD63 antigen, [Score=50.4, Expect=7e-07]} {Dmel: FBgn0027865, Tsp96F, Tetraspanin 96F, [Score=48.1, Expect=3e-06]} {Celegans: WBGene00023491, tsp-21, Tetraspanin, [RH, Score=55.8, Expect=8e-09]} {Smed: dd_Smed_v6_854_1_1, dd_Smed_v6_854_1_1, [RH, Score=123, Expect=3e-33]} {RNA1509_13523, RNA1509_24250, RNA1509_39608, RNA1509_5967} {RNA1310_20875, RNA1509_13523, RNA1509_24250, RNA1509_39608, RNA1509_5967} {RNA1509_13523, RNA1509_24250, RNA1509_39608, RNA1509_5967, RNA815_8669.1}
41. MligTC455_45998 1124 23.42 Mlig455_004117, Mlig455_060440

Neo: -

Age: -

GNAO1 1.667 - 0.716 - - - 0.951

Mlig455_004117 {REF} {Length: 3586} {Pfam: G-protein alpha subunit [PF00503.22, score=408.5]; ADP-ribosylation factor family [PF00025.23, score=62.4]; Gtr1/RagA G protein conserved region [PF04670.14, score=24.2]} {Human: ENSG00000087258, GNAO1, G protein subunit alpha o1, [RH, Score=617, Expect=0.0]} {Mouse: ENSMUSG00000031748, Gnao1, guanine nucleotide binding protein, alpha O, [RH, Score=614, Expect=0.0]} {Dmel: FBgn0001122, Galphao, G protein alpha o subunit, [RH, Score=649, Expect=0.0]} {Celegans: WBGene00001648, goa-1, Guanine nucleotide-binding protein G(o) subunit alpha, [RH, Score=643, Expect=0.0]} {Smed: dd_Smed_v6_1656_0_1, dd_Smed_v6_1656_0_1, [RH, Score=674, Expect=0.0]} {RNA1509_41742, RNA1509_7653} {RNA1310_5003, RNA1509_41742, RNA1509_7653} {RNA1509_41742, RNA1509_7653, RNA815_2342}

Mlig455_060440 {REF} {Length: 3397} {Pfam: G-protein alpha subunit [PF00503.22, score=408.5]; ADP-ribosylation factor family [PF00025.23, score=62.4]; Gtr1/RagA G protein conserved region [PF04670.14, score=24.2]} {Human: ENSG00000087258, GNAO1, G protein subunit alpha o1, [RH, Score=617, Expect=0.0]} {Mouse: ENSMUSG00000031748, Gnao1, guanine nucleotide binding protein, alpha O, [RH, Score=614, Expect=0.0]} {Dmel: FBgn0001122, Galphao, G protein alpha o subunit, [RH, Score=649, Expect=0.0]} {Celegans: WBGene00001648, goa-1, Guanine nucleotide-binding protein G(o) subunit alpha, [RH, Score=643, Expect=0.0]} {Smed: dd_Smed_v6_1656_0_1, dd_Smed_v6_1656_0_1, [RH, Score=674, Expect=0.0]} {RNA1509_7653} {RNA1310_5003} {RNA815_2342}
42. MligTC455_37286 90 1.88 Mlig455_025470, Mlig455_071141

Neo: -

Age: -

GRIA2 0.991 - - - - 0.991 -

Mlig455_025470 {REF} {Length: 3546} {Pfam: Ligand-gated ion channel [PF00060.28, score=83.8]; Receptor family ligand binding region [PF01094.30, score=50.7]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=44.9]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=120, Expect=2e-27]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=119, Expect=7e-27]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=118, Expect=2e-26]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=117, Expect=4e-26]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=116, Expect=6e-26]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=115, Expect=1e-25]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=115, Expect=2e-25]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=118, Expect=1e-26]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=118, Expect=9e-27]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=117, Expect=2e-26]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=116, Expect=4e-26]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=116, Expect=4e-26]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=115, Expect=6e-26]} {Dmel: FBgn0038837, CG3822, [Score=153, Expect=5e-38]} {Celegans: WBGene00001615, glr-4, GLutamate Receptor family (AMPA), [Score=112, Expect=3e-25]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=228, Expect=9e-67]} {RNA1310_33468}

Mlig455_071141 {REF} {Length: 3783} {Pfam: Ligand-gated ion channel [PF00060.28, score=83.8]; Receptor family ligand binding region [PF01094.30, score=50.3]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=44.8]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=118, Expect=2e-26]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=118, Expect=2e-26]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=115, Expect=1e-25]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=115, Expect=2e-25]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=114, Expect=2e-25]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=113, Expect=5e-25]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=117, Expect=3e-26]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=117, Expect=1e-26]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=115, Expect=5e-26]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=115, Expect=6e-26]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=113, Expect=3e-25]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=112, Expect=6e-25]} {Dmel: FBgn0038837, CG3822, [Score=154, Expect=4e-38]} {Celegans: WBGene00001615, glr-4, GLutamate Receptor family (AMPA), [Score=112, Expect=3e-25]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=228, Expect=7e-67]} {RNA1310_33468}
43. MligTC455_09202 9 0.19 Mlig455_029853

Neo: -

Age: -

0.99 - - - - 0.990 - Mlig455_029853 {REF} {Length: 837} {NoTransDecoderORF}
44. MligTC455_27323 89 1.86 Mlig455_018463

Neo: -

Age: -

0.986 - - - - 0.986 - Mlig455_018463 {REF} {Length: 3840} {RNA1509_42925} {RNA1310_28493} {RNA815_4396.1}
45. MligTC455_50100 86 1.8 Mlig455_031032

Neo: -

Age: -

Region-enriched R8: 4.201/0.00579

SLC4A11 0.98 - - - - 0.980 - Mlig455_031032 {REF} {Length: 3497} {Pfam: HCO3- transporter family [PF00955.23, score=526.7]; Band 3 cytoplasmic domain [PF07565.15, score=23.8]; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 [PF00359.24, score=22.0]} {Human: ENSG00000088836, SLC4A11, solute carrier family 4 member 11, [RH, Score=547, Expect=3e-180]} {Mouse: ENSMUSG00000074796, Slc4a11, solute carrier family 4, sodium bicarbonate transporter-like, member 11, [RH, Score=533, Expect=2e-175]} {Dmel: FBgn0259111, Ndae1, Na[+]-driven anion exchanger 1, [Score=242, Expect=3e-66]} {Celegans: WBGene00019018, abts-3, Anion transporter ABTS-3; Anion/Bicarbonate TranSporter family, [RH, Score=680, Expect=0.0]} {Smed: dd_Smed_v6_16577_0_1, dd_Smed_v6_16577_0_1, [RH, Score=904, Expect=0.0]} {RNA1509_55902} {RNA1310_18543} {RNA815_14015}
46. MligTC455_10456 173 3.6 Mlig455_036936

Neo: -

Age: Down-Up-Down

0.975 - - - - 0.975 - Mlig455_036936 {REF} {Length: 2942} {RNA1509_52192} {RNA1310_9569.2, RNA1509_52192} {RNA1509_52192, RNA815_10835}
47. MligTC455_11765 292 6.08 Mlig455_032580, Mlig455_032642

Neo: -

Age: -

Region-specific R2: 6.434

Region-enriched R2: 4.662/0.03055

0.973 - - - - 0.973 -

Mlig455_032580 {REF} {Length: 565} {RNA1509_42630} {RNA1310_64208} {RNA815_32993}

Mlig455_032642 {REF} {Length: 663} {RNA1509_42630} {RNA1310_64208} {RNA815_32993}
48. MligTC455_28600 90 1.88 Mlig455_010981

Neo: -

Age: -

0.973 - - 0.973 - - - Mlig455_010981 {REF} {Length: 5815} {RNA1509_37486} {RNA1310_30004.1} {RNA815_31633}
49. MligTC455_39371 221 4.6 Mlig455_068978

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.390

ABCG4 0.972 0.972 - - - - - Mlig455_068978 {REF} {Length: 5136} {TRANSSPLICED} {Pfam: ABC-2 type transporter [PF01061.26, score=156.2]; ABC transporter [PF00005.29, score=100.1]; ABC-2 type transporter [PF19055.2, score=74.6]; RsgA GTPase [PF03193.18, score=25.8]; RecF/RecN/SMC N terminal domain [PF02463.21, score=24.2]; AAA domain, putative AbiEii toxin, Type IV TA system [PF13304.8, score=18.8]} {Human: ENSG00000172350, ABCG4, ATP binding cassette subfamily G member 4, [RH, Score=647, Expect=0.0]; ENSG00000160179, ABCG1, ATP binding cassette subfamily G member 1, [RH, Score=641, Expect=0.0]} {Mouse: ENSMUSG00000032131, Abcg4, ATP binding cassette subfamily G member 4, [RH, Score=657, Expect=0.0]; ENSMUSG00000024030, Abcg1, ATP binding cassette subfamily G member 1, [RH, Score=637, Expect=0.0]} {Dmel: FBgn0020762, Atet, ABC transporter expressed in trachea, [RH, Score=610, Expect=0.0]} {Celegans: WBGene00015479, wht-1, ABC transporter ATP-binding protein/permease wht-1, [RH, Score=272, Expect=1e-81]} {Smed: dd_Smed_v6_4142_0_1, dd_Smed_v6_4142_0_1, [RH, Score=413, Expect=1e-139]} {RNA1509_38106} {RNA1310_4533, RNA1509_38106} {RNA1509_38106, RNA815_2836}
50. MligTC455_28141 69 1.45 Mlig455_011472, Mlig455_069148

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=6.810

0.97 - - - - 0.970 -

Mlig455_011472 {REF} {Length: 3013} {TRANSSPLICED} {Smed: dd_Smed_v6_17025_0_1, dd_Smed_v6_17025_0_1, [Score=43.9, Expect=6e-06]} {RNA1509_45809} {RNA1310_850} {RNA815_1208.1}

Mlig455_069148 {REF} {Length: 2970} {TRANSSPLICED} {Smed: dd_Smed_v6_17025_0_1, dd_Smed_v6_17025_0_1, [Score=43.9, Expect=6e-06]} {RNA1509_45809} {RNA1310_850} {RNA815_1208.1}
51. MligTC455_01652 149 3.1 Mlig455_018970

Neo: -

Age: Down-Up-Down

Region-enriched R2: 3.522/0.03301

0.967 - - - - 0.967 - Mlig455_018970 {REF} {Length: 756} {Pfam: Pancreatic hormone peptide [PF00159.20, score=41.3]} {Smed: dd_Smed_v6_6375_0_1, dd_Smed_v6_6375_0_1, [Score=40.0, Expect=7e-06]} {RNA1310_45503} {RNA815_39878}
52. MligTC455_18858 15 0.32 Mlig455_067213

Neo: -

Age: -

0.967 - - - - 0.967 - Mlig455_067213 {REF} {Length: 1285} {NoTransDecoderORF} {RNA1509_56890} {RNA1310_81565}
53. MligTC455_22710 32 0.67 Mlig455_037832

Neo: Int S/G2/M

Age: Down-Down-Up

0.966 - - - - 0.966 - Mlig455_037832 {REF} {Length: 2923} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=97.2]; Capsular polysaccharide synthesis protein [PF05704.14, score=38.2]} {Smed: dd_Smed_v6_13661_0_2, dd_Smed_v6_13661_0_2, [Score=78.2, Expect=8e-16]} {RNA1509_35288} {RNA1310_25576.1} {RNA815_8208}
54. MligTC455_39024 11 0.22 Mlig455_023941

Neo: -

Age: -

GALR2 0.966 - - - - 0.966 - Mlig455_023941 {REF} {Length: 4051} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=137.2]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=31.9]} {Human: ENSG00000182687, GALR2, galanin receptor 2, [Score=99.0, Expect=5e-22]} {Mouse: ENSMUSG00000025905, Oprk1, opioid receptor, kappa 1, [Score=99.4, Expect=2e-22]; ENSMUSG00000020793, Galr2, galanin receptor 2, [Score=97.1, Expect=1e-21]; ENSMUSG00000050511, Oprd1, opioid receptor, delta 1, [Score=95.9, Expect=4e-21]} {Dmel: FBgn0004841, TkR86C, Tachykinin-like receptor at 86C, [Score=97.8, Expect=2e-21]} {Celegans: WBGene00022004, npr-22, NeuroPeptide Receptor family, [Score=84.0, Expect=3e-17]} {Smed: dd_Smed_v6_16861_0_1, dd_Smed_v6_16861_0_1, [Score=98.2, Expect=3e-22]} {RNA1509_29740} {RNA1310_36564} {RNA815_34523}
55. MligTC455_40716 197 4.1 Mlig455_067129

Neo: -

Age: Down-Down-Up

PDE1C 0.966 - - - - 0.966 - Mlig455_067129 {REF} {Length: 2647} {Pfam: 3'5'-cyclic nucleotide phosphodiesterase [PF00233.21, score=260.8]; 3'5'-cyclic nucleotide phosphodiesterase N-terminal [PF08499.14, score=36.8]} {Human: ENSG00000154678, PDE1C, phosphodiesterase 1C, [Score=375, Expect=3e-121]} {Mouse: ENSMUSG00000004347, Pde1c, phosphodiesterase 1C, [Score=383, Expect=1e-124]} {Dmel: FBgn0264815, Pde1c, Phosphodiesterase 1c, [Score=338, Expect=1e-107]} {Celegans: WBGene00011433, pde-1, Probable 3',5'-cyclic phosphodiesterase pde-1, [Score=342, Expect=2e-110]} {Smed: dd_Smed_v6_26758_0_1, dd_Smed_v6_26758_0_1, [Score=419, Expect=1e-140]} {RNA1509_46211} {RNA1310_29930, RNA1509_46211} {RNA1509_46211, RNA815_22606}
56. MligTC455_18607 203 4.23 Mlig455_012344, Mlig455_012722

Neo: -

Age: -

Region-enriched R2: 3.338/0.02204

ANKRD63 0.965 - - - - 0.965 -

Mlig455_012344 {REF} {Length: 1989} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=77.3]; Ankyrin repeats (many copies) [PF13637.8, score=67.3]; Ankyrin repeat [PF00023.32, score=56.6]; Ankyrin repeats (many copies) [PF13857.8, score=50.3]; Ankyrin repeat [PF13606.8, score=47.6]} {Human: ENSG00000230778, ANKRD63, ankyrin repeat domain 63, [RH, Score=129, Expect=1e-33]} {Mouse: ENSMUSG00000078137, Ankrd63, ankyrin repeat domain 63, [RH, Score=129, Expect=1e-33]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=55.5, Expect=5e-08]} {Celegans: WBGene00006882, vab-19, VAB-19, [Score=52.0, Expect=5e-07]} {Smed: dd_Smed_v6_11187_0_1, dd_Smed_v6_11187_0_1, [Score=59.3, Expect=2e-09]} {RNA1310_37830} {RNA815_38436}

Mlig455_012722 {REF} {Length: 2256} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=77.2]; Ankyrin repeats (many copies) [PF13637.8, score=67.3]; Ankyrin repeat [PF00023.32, score=56.6]; Ankyrin repeats (many copies) [PF13857.8, score=50.3]; Ankyrin repeat [PF13606.8, score=47.6]} {Human: ENSG00000230778, ANKRD63, ankyrin repeat domain 63, [RH, Score=129, Expect=1e-33]} {Mouse: ENSMUSG00000078137, Ankrd63, ankyrin repeat domain 63, [RH, Score=129, Expect=1e-33]} {Dmel: FBgn0031473, CG3104, [Score=54.7, Expect=5e-08]} {Celegans: WBGene00006882, vab-19, VAB-19, [Score=52.0, Expect=5e-07]} {Smed: dd_Smed_v6_11187_0_2, dd_Smed_v6_11187_0_2, [Score=59.7, Expect=1e-09]} {RNA1310_37830} {RNA815_38436}
57. MligTC455_37879 44 0.92 Mlig455_043317

Neo: -

Age: -

0.965 - - 0.965 - - - Mlig455_043317 {REF} {Length: 2821} {RNA1310_10915} {RNA815_31437}
58. MligTC455_49513 233 4.85 Mlig455_022846

Neo: -

Age: -

AGBL2 0.965 - - - - - 0.965 Mlig455_022846 {REF} {Length: 5485} {Pfam: Cytosolic carboxypeptidase N-terminal domain [PF18027.3, score=73.4]; Zinc carboxypeptidase [PF00246.26, score=69.4]} {Human: ENSG00000285501, AGBL2, ATP/GTP binding protein like 2, [RH, Score=598, Expect=0.0]; ENSG00000165923, AGBL2, ATP/GTP binding protein like 2, [RH, Score=598, Expect=0.0]; ENSG00000146856, AGBL3, ATP/GTP binding protein like 3, [RH, Score=591, Expect=0.0]} {Mouse: ENSMUSG00000038836, Agbl3, ATP/GTP binding protein-like 3, [RH, Score=594, Expect=0.0]; ENSMUSG00000040812, Agbl2, ATP/GTP binding protein-like 2, [RH, Score=593, Expect=0.0]} {Dmel: FBgn0265726, Nna1, Nna1 carboxypeptidase, [RH, Score=581, Expect=0.0]} {Celegans: WBGene00018995, ccpp-1, Cytosolic carboxypeptidase 1, [Score=287, Expect=4e-81]} {Smed: dd_Smed_v6_13450_0_1, dd_Smed_v6_13450_0_1, [RH, Score=624, Expect=0.0]} {RNA1509_10895} {RNA1310_2786.1} {RNA815_1445.1}
59. MligTC455_05689 31 0.65 Mlig455_050118

Neo: -

Age: -

0.964 - - - - 0.964 - Mlig455_050118 {REF} {Length: 1063} {RNA1310_14920} {RNA815_35004}
60. MligTC455_30801 483 10.05 Mlig455_027631, Mlig455_027642

Neo: -

Age: Up-Down-Down

Region-enriched R4: 2.277/0.03108

TRPM7 0.962 0.962 - - - - -

Mlig455_027631 {REF} {Length: 3904} {Pfam: Ion transport protein [PF00520.33, score=35.0]} {Human: ENSG00000092439, TRPM7, transient receptor potential cation channel subfamily M member 7, [Score=79.0, Expect=3e-14]} {Mouse: ENSMUSG00000027365, Trpm7, transient receptor potential cation channel, subfamily M, member 7, [Score=73.9, Expect=5e-13]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=81.6, Expect=2e-15]} {Celegans: WBGene00001651, gon-2, Transient receptor potential channel, [Score=70.5, Expect=3e-12]} {Smed: dd_Smed_v6_26251_0_1, dd_Smed_v6_26251_0_1, [Score=100, Expect=1e-21]} {RNA1509_8759} {RNA1310_4330.3, RNA1509_8759} {RNA1509_8759, RNA815_1383.1}

Mlig455_027642 {REF} {Length: 4185} {Pfam: Ion transport protein [PF00520.33, score=35.0]} {Human: ENSG00000092439, TRPM7, transient receptor potential cation channel subfamily M member 7, [Score=76.3, Expect=1e-13]} {Mouse: ENSMUSG00000027365, Trpm7, transient receptor potential cation channel, subfamily M, member 7, [Score=71.6, Expect=3e-12]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=81.3, Expect=2e-15]} {Celegans: WBGene00001651, gon-2, Transient receptor potential channel, [Score=70.5, Expect=3e-12]} {Smed: dd_Smed_v6_26251_0_1, dd_Smed_v6_26251_0_1, [Score=100, Expect=1e-21]} {RNA1509_8759} {RNA1310_3171.2} {RNA815_1383.1}
61. MligTC455_43137 118 2.46 Mlig455_043159

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.878

Region-enriched R2: 5.988/0.00166
Region-enriched R4: 3.958/0.04103

0.962 - - - - 0.962 - Mlig455_043159 {REF} {Length: 1651} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=25.7]} {RNA1509_48871} {RNA1310_23692, RNA1509_48871} {RNA1509_48871, RNA815_11317}
62. MligTC455_45181 516 10.76 Mlig455_015976, Mlig455_015996

Neo: -

Age: -

0.96 - - - - 0.960 -

Mlig455_015976 {REF} {Length: 2623} {Pfam: TIR domain [PF13676.8, score=74.6]} {Smed: dd_Smed_v6_6471_0_1, dd_Smed_v6_6471_0_1, [Score=139, Expect=7e-35]} {RNA1509_16563} {RNA1310_7485} {RNA815_2652}

Mlig455_015996 {REF} {Length: 3380} {Pfam: TIR domain [PF13676.8, score=72.7]} {Smed: dd_Smed_v6_6471_0_1, dd_Smed_v6_6471_0_1, [Score=135, Expect=1e-33]} {RNA1509_16563} {RNA1310_7485, RNA1509_16563} {RNA1509_16563, RNA815_2652}
63. MligTC455_46982 256 5.34 Mlig455_044826

Neo: -

Age: -

SYN3 0.96 - - - - 0.960 - Mlig455_044826 {REF} {Length: 2562} {TRANSSPLICED} {Pfam: Synapsin, ATP binding domain [PF02750.16, score=168.9]} {Human: ENSG00000185666, SYN3, synapsin III, [RH, Score=176, Expect=7e-53]} {Mouse: ENSMUSG00000059602, Syn3, synapsin III, [Score=173, Expect=2e-49]; ENSMUSG00000037217, Syn1, synapsin I, [Score=170, Expect=6e-48]} {Dmel: FBgn0004575, Syn, Synapsin, [Score=186, Expect=1e-54]} {Celegans: WBGene00004913, snn-1, SyNapsiN; Synapsin, [Score=105, Expect=6e-26]} {Smed: dd_Smed_v6_3135_0_2, dd_Smed_v6_3135_0_2, [RH, Score=216, Expect=3e-68]} {RNA1310_32498} {RNA815_34432}
64. MligTC455_12253 21 0.45 Mlig455_042075

Neo: -

Age: -

0.959 - - - - 0.959 - Mlig455_042075 {REF} {Length: 1846} {Smed: dd_Smed_v6_18803_0_1, dd_Smed_v6_18803_0_1, [Score=247, Expect=2e-76]} {RNA1310_26226} {RNA815_49309}
65. MligTC455_17562 108 2.25 Mlig455_022496

Neo: -

Age: -

NECAB3 0.959 - - - - 0.959 - Mlig455_022496 {REF} {Length: 1499} {Pfam: EF hand [PF00036.34, score=34.0]; EF-hand domain [PF13405.8, score=33.4]; EF-hand domain pair [PF13833.8, score=29.2]; EF-hand domain pair [PF13499.8, score=28.3]; Antibiotic biosynthesis monooxygenase [PF03992.18, score=22.0]; EF hand [PF13202.8, score=21.3]} {Human: ENSG00000125967, NECAB3, N-terminal EF-hand calcium binding protein 3, [RH, Score=189, Expect=7e-57]; ENSG00000123119, NECAB1, N-terminal EF-hand calcium binding protein 1, [RH, Score=186, Expect=1e-55]} {Mouse: ENSMUSG00000040536, Necab1, N-terminal EF-hand calcium binding protein 1, [RH, Score=191, Expect=7e-58]; ENSMUSG00000027489, Necab3, N-terminal EF-hand calcium binding protein 3, [RH, Score=191, Expect=9e-58]} {RNA1509_46831} {RNA1310_24461} {RNA815_25216}
66. MligTC455_18996 34 0.71 Mlig455_032938

Neo: -

Age: -

0.959 - - - - 0.959 - Mlig455_032938 {REF} {Length: 1648} {Pfam: Transposase DDE domain [PF01609.23, score=18.8]} {RNA1509_39626} {RNA1310_29809} {RNA815_13636}
67. MligTC455_44373 201 4.19 Mlig455_049801

Neo: -

Age: -

0.959 - - - - 0.959 - Mlig455_049801 {REF} {Length: 3159} {Pfam: Innexin [PF00876.20, score=306.5]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=81.6, Expect=3e-17]} {Celegans: WBGene00002123, inx-1, Innexin, [Score=239, Expect=1e-76]} {Smed: dd_Smed_v6_6114_0_3, dd_Smed_v6_6114_0_3, [Score=384, Expect=1e-131]} {RNA1509_40288} {RNA1310_5287.1} {RNA815_16730}
68. MligTC455_47643 5 0.1 Mlig455_050641

Neo: -

Age: -

0.959 - - - - 0.959 - Mlig455_050641 {REF} {Length: 572} {RNA1310_87761} {RNA815_48552}
69. MligTC455_15460 271 5.65 Mlig455_001644, Mlig455_001708

Neo: -

Age: -

Region-enriched R8: 3.592/0.03504
Region-enriched R7: 3.324/0.02643

0.958 - - 0.958 - - -

Mlig455_001644 {REF} {Length: 1595} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=28.7]} {Smed: dd_Smed_v6_19599_0_1, dd_Smed_v6_19599_0_1, [Score=137, Expect=2e-36]} {RNA1509_56048} {RNA1310_10124} {RNA815_17803}

Mlig455_001708 {REF} {Length: 2658} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=151.7]} {Celegans: WBGene00022815, asic-1, Degenerin-like protein asic-1, [Score=50.8, Expect=2e-06]} {Smed: dd_Smed_v6_28097_0_1, dd_Smed_v6_28097_0_1, [Score=332, Expect=4e-107]} {RNA1509_56048} {RNA1310_10124, RNA1509_56048} {RNA1509_56048, RNA815_17803}
70. MligTC455_11732 15 0.32 Mlig455_001499, Mlig455_001517

Neo: -

Age: -

GABBR2 0.957 - - - - 0.957 -

Mlig455_001499 {REF} {Length: 2516} {Pfam: 7 transmembrane sweet-taste receptor of 3 GCPR [PF00003.24, score=166.2]; Receptor family ligand binding region [PF01094.30, score=21.1]} {Human: ENSG00000136928, GABBR2, gamma-aminobutyric acid type B receptor subunit 2, [Score=219, Expect=7e-61]} {Mouse: ENSMUSG00000039809, Gabbr2, gamma-aminobutyric acid (GABA) B receptor, 2, [Score=219, Expect=5e-61]} {Dmel: FBgn0027575, GABA-B-R2, metabotropic GABA-B receptor subtype 2, [Score=202, Expect=4e-55]} {Celegans: WBGene00022675, gbb-2, GABA B receptor subunit; GABAB2 receptor subunit, [Score=207, Expect=2e-57]} {Smed: dd_Smed_v6_51663_0_1, dd_Smed_v6_51663_0_1, [Score=151, Expect=1e-41]} {RNA1310_28849} {RNA815_36011}

Mlig455_001517 {REF} {Length: 2539} {Pfam: 7 transmembrane sweet-taste receptor of 3 GCPR [PF00003.24, score=166.0]; Receptor family ligand binding region [PF01094.30, score=52.9]} {Human: ENSG00000136928, GABBR2, gamma-aminobutyric acid type B receptor subunit 2, [Score=236, Expect=1e-66]} {Mouse: ENSMUSG00000039809, Gabbr2, gamma-aminobutyric acid (GABA) B receptor, 2, [Score=236, Expect=1e-66]} {Dmel: FBgn0027575, GABA-B-R2, metabotropic GABA-B receptor subtype 2, [Score=220, Expect=6e-61]} {Celegans: WBGene00022675, gbb-2, GABA B receptor subunit; GABAB2 receptor subunit, [Score=228, Expect=2e-64]} {Smed: dd_Smed_v6_51663_0_1, dd_Smed_v6_51663_0_1, [Score=152, Expect=8e-42]} {RNA1310_28849} {RNA815_36011}
71. MligTC455_13799 33 0.69 Mlig455_042825, Mlig455_063144

Neo: -

Age: -

GRIA2, GRIK1 0.957 - - - - 0.957 -

Mlig455_042825 {REF} {Length: 2617} {Pfam: Ligand-gated ion channel [PF00060.28, score=107.4]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=42.5]; Receptor family ligand binding region [PF01094.30, score=28.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=27.3]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=147, Expect=5e-36]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=142, Expect=2e-34]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=141, Expect=3e-34]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=140, Expect=8e-34]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=140, Expect=1e-33]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=147, Expect=4e-36]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=143, Expect=6e-35]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=141, Expect=3e-34]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=140, Expect=5e-34]} {Dmel: FBgn0039927, CG11155, [Score=160, Expect=1e-40]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=130, Expect=3e-31]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=238, Expect=1e-71]} {RNA1310_25150} {RNA815_13999}

Mlig455_063144 {REF} {Length: 2554} {Pfam: Ligand-gated ion channel [PF00060.28, score=107.4]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=42.6]; Receptor family ligand binding region [PF01094.30, score=31.9]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=27.5]} {Human: ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=150, Expect=4e-37]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=147, Expect=4e-36]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=147, Expect=3e-36]} {Mouse: ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=152, Expect=9e-38]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=147, Expect=4e-36]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=145, Expect=1e-35]} {Dmel: FBgn0038837, CG3822, [Score=162, Expect=2e-41]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=130, Expect=3e-31]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=238, Expect=9e-72]} {RNA1310_25150} {RNA815_13999}
72. MligTC455_31464 20 0.41 Mlig455_057157

Neo: -

Age: -

0.957 - - - - 0.957 - Mlig455_057157 {REF} {Length: 1285} {Pfam: Methyltransferase FkbM domain [PF05050.14, score=38.2]} {Smed: dd_Smed_v6_13824_0_1, dd_Smed_v6_13824_0_1, [RH, Score=47.0, Expect=2e-07]} {RNA1509_6604} {RNA1310_12860.1} {RNA815_6128.1}
73. MligTC455_46480 3489 72.68 Mlig455_029170

Neo: -

Age: -

PLSCR3 0.957 - - - 0.957 - - Mlig455_029170 {REF} {Length: 1715} {Pfam: Scramblase [PF03803.17, score=198.5]} {Human: ENSG00000284009, PLSCR3, phospholipid scramblase 3, [Score=182, Expect=3e-56]; ENSG00000187838, PLSCR3, phospholipid scramblase 3, [Score=182, Expect=3e-56]} {Mouse: ENSMUSG00000019461, Plscr3, phospholipid scramblase 3, [Score=180, Expect=1e-55]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=149, Expect=2e-44]} {Celegans: WBGene00011935, scrm-1, Phospholipid scramblase, [Score=134, Expect=2e-38]} {Smed: dd_Smed_v6_6988_0_1, dd_Smed_v6_6988_0_1, [Score=205, Expect=3e-66]} {RNA1509_24275, RNA1509_6872} {RNA1310_19869.1, RNA1509_24275, RNA1509_6872} {RNA1509_24275, RNA1509_6872, RNA815_8634}
74. MligTC455_50329 62 1.28 Mlig455_021856, Mlig455_021933

Neo: -

Age: -

0.957 - - - - 0.957 -

Mlig455_021856 {REF} {Length: 1659} {NoTransDecoderORF} {RNA1310_38830} {RNA815_11698.1}

Mlig455_021933 {REF} {Length: 850} {NoTransDecoderORF} {RNA1310_41987.1} {RNA815_11698.1}
75. MligTC455_13948 28 0.59 Mlig455_047707

Neo: -

Age: -

CELSR2 0.956 - - - - 0.956 - Mlig455_047707 {REF} {Length: 3244} {Pfam: Cadherin domain [PF00028.19, score=132.5]} {Human: ENSG00000143126, CELSR2, cadherin EGF LAG seven-pass G-type receptor 2, [Score=159, Expect=6e-39]; ENSG00000008300, CELSR3, cadherin EGF LAG seven-pass G-type receptor 3, [Score=154, Expect=3e-37]; ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=152, Expect=9e-37]} {Mouse: ENSMUSG00000016028, Celsr1, cadherin, EGF LAG seven-pass G-type receptor 1, [Score=163, Expect=3e-40]; ENSMUSG00000068740, Celsr2, cadherin, EGF LAG seven-pass G-type receptor 2, [Score=159, Expect=5e-39]} {Dmel: FBgn0038439, Cad89D, Cadherin 89D, [Score=167, Expect=6e-42]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=141, Expect=8e-34]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [Score=115, Expect=5e-26]} {RNA1310_40769} {RNA815_46115}
76. MligTC455_16358 1175 24.47 Mlig455_039878

Neo: -

Age: -

Region-specific R2: 4.659

Region-enriched R2: 4.310/0.00000

0.956 - - - - 0.956 - Mlig455_039878 {REF} {Length: 1188} {RNA1509_60020} {RNA1310_35099.1, RNA1509_60020} {RNA1509_60020, RNA815_1356.1}
77. MligTC455_25169 62 1.29 Mlig455_017959

Neo: Irradiation

Age: -

SPECC1L 0.956 - - 0.956 - - - Mlig455_017959 {REF} {Length: 4845} {TRANSSPLICED} {Pfam: Calponin homology (CH) domain [PF00307.33, score=68.3]; CAMSAP CH domain [PF11971.10, score=22.3]} {Human: ENSG00000100014, SPECC1L, sperm antigen with calponin homology and coiled-coil domains 1 like, [RH, Score=264, Expect=5e-73]} {Mouse: ENSMUSG00000033444, Specc1l, sperm antigen with calponin homology and coiled-coil domains 1-like, [RH, Score=261, Expect=3e-72]} {Dmel: FBgn0025633, CG13366, [RH, Score=187, Expect=3e-48]} {Celegans: WBGene00020530, T15B12.1, [Score=128, Expect=3e-31]} {Smed: dd_Smed_v6_7845_0_1, dd_Smed_v6_7845_0_1, [Score=159, Expect=7e-40]} {RNA1509_39130, RNA1509_7795} {RNA1310_10182.1, RNA1509_39130, RNA1509_7795} {RNA1509_39130, RNA1509_7795, RNA815_11375}
78. MligTC455_27800 102 2.12 Mlig455_016297

Neo: -

Age: Down-Down-Up

0.956 - - 0.956 - - - Mlig455_016297 {REF} {Length: 4934} {RNA1509_52468} {RNA1310_42461} {RNA815_10757}
79. MligTC455_45052 26 0.54 Mlig455_047471

Neo: -

Age: Up-Down-Up

0.956 - - - - 0.956 - Mlig455_047471 {REF} {Length: 3750} {TRANSSPLICED} {RNA1310_38765} {RNA815_44260}
80. MligTC455_07029 51 1.07 Mlig455_030754

Neo: -

Age: Up-Down-Down

KIF1A 0.954 - - - - 0.954 - Mlig455_030754 {REF} {Length: 6754} {Pfam: Kinesin motor domain [PF00225.25, score=361.6]; Kinesin-associated [PF16183.7, score=198.6]; Kinesin protein [PF12473.10, score=104.3]; Microtubule binding [PF16796.7, score=63.6]; PH domain [PF00169.31, score=42.1]; Kinesin protein 1B [PF12423.10, score=37.6]; FHA domain [PF00498.28, score=32.6]; Inner membrane component of T3SS, cytoplasmic domain [PF16697.7, score=26.1]} {Human: ENSG00000130294, KIF1A, kinesin family member 1A, [Score=1405, Expect=0.0]} {Mouse: ENSMUSG00000014602, Kif1a, kinesin family member 1A, [Score=1404, Expect=0.0]} {Dmel: FBgn0267002, unc-104, uncoordinated-104, [Score=1415, Expect=0.0]} {Celegans: WBGene00006831, unc-104, Kinesin-like protein unc-104, [RH, Score=1292, Expect=0.0]} {Smed: dd_Smed_v6_7108_0_2, dd_Smed_v6_7108_0_2, [Score=1552, Expect=0.0]} {RNA1509_24107} {RNA1310_2896} {RNA815_13100}
81. MligTC455_44209 764 15.92 Mlig455_011059

Neo: -

Age: -

EGR1 0.954 - - - - - 0.954 Mlig455_011059 {REF} {Length: 2031} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=54.2]; Zinc-finger double domain [PF13465.8, score=48.5]; C2H2-type zinc finger [PF13894.8, score=44.8]; C2H2-type zinc finger [PF13912.8, score=32.9]} {Human: ENSG00000120738, EGR1, early growth response 1, [RH, Score=159, Expect=1e-43]; ENSG00000179388, EGR3, early growth response 3, [RH, Score=155, Expect=2e-43]; ENSG00000122877, EGR2, early growth response 2, [RH, Score=154, Expect=6e-42]} {Mouse: ENSMUSG00000038418, Egr1, early growth response 1, [RH, Score=159, Expect=9e-44]; ENSMUSG00000033730, Egr3, early growth response 3, [RH, Score=155, Expect=2e-43]; ENSMUSG00000116458, Egr2, early growth response 2, [RH, Score=154, Expect=3e-42]; ENSMUSG00000037868, Egr2, early growth response 2, [RH, Score=154, Expect=3e-42]} {Dmel: FBgn0003499, sr, stripe, [RH, Score=163, Expect=5e-44]} {Celegans: WBGene00007772, egrh-1, EGR (Early Growth factor Response factor) Homolog, [RH, Score=153, Expect=3e-42]} {Smed: dd_Smed_v6_7091_0_1, dd_Smed_v6_7091_0_1, [RH, Score=136, Expect=1e-36]} {RNA1509_16885, RNA1509_28595} {RNA1310_14689, RNA1509_16885, RNA1509_28595} {RNA1509_16885, RNA1509_28595, RNA815_10071.1}
82. MligTC455_47918 119 2.48 Mlig455_006053

Neo: -

Age: Down-Down-Up

PODNL1 0.954 - - - - 0.954 - Mlig455_006053 {REF} {Length: 2760} {Pfam: Leucine rich repeat [PF13855.8, score=191.7]; Leucine Rich repeats (2 copies) [PF12799.9, score=113.3]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=36.9]; Leucine Rich Repeat [PF00560.35, score=35.8]; Leucine Rich repeat [PF13516.8, score=34.6]; Leucine-rich repeat [PF14580.8, score=29.3]; Leucine rich repeat C-terminal domain [PF01463.26, score=21.8]} {Human: ENSG00000132000, PODNL1, podocan like 1, [Score=90.1, Expect=4e-18]; ENSG00000099769, IGFALS, insulin like growth factor binding protein acid labile subunit, [Score=87.8, Expect=3e-17]; ENSG00000205213, LGR4, leucine rich repeat containing G protein-coupled receptor 4, [Score=87.8, Expect=4e-17]; ENSG00000137507, LRRC32, leucine rich repeat containing 32, [Score=87.4, Expect=4e-17]} {Mouse: ENSMUSG00000063765, Chadl, chondroadherin-like, [Score=96.3, Expect=5e-20]; ENSMUSG00000052316, Lrrc15, leucine rich repeat containing 15, [Score=92.4, Expect=7e-19]; ENSMUSG00000046070, Igfals, insulin-like growth factor binding protein, acid labile subunit, [Score=92.0, Expect=8e-19]} {Dmel: FBgn0261269, conv, convoluted, [Score=109, Expect=4e-24]} {Celegans: WBGene00016974, lron-15, ELRR (Extracellular Leucine-Rich Repeat) ONly, [Score=92.0, Expect=9e-19]} {Smed: dd_Smed_v6_6669_0_1, dd_Smed_v6_6669_0_1, [Score=92.8, Expect=3e-19]} {RNA1509_47596} {RNA1310_6895, RNA1509_47596} {RNA1509_47596, RNA815_5082}
83. MligTC455_19694 101 2.1 Mlig455_019126

Neo: -

Age: -

HMCN1 0.953 - - - - 0.953 - Mlig455_019126 {REF} {Length: 1904} {Pfam: Immunoglobulin domain [PF13927.8, score=96.3]; Immunoglobulin I-set domain [PF07679.18, score=82.1]; Immunoglobulin V-set domain [PF07686.19, score=63.8]; Immunoglobulin domain [PF00047.27, score=57.8]; Immunoglobulin domain [PF13895.8, score=55.6]} {Human: ENSG00000143341, HMCN1, hemicentin 1, [Score=88.6, Expect=8e-18]} {Mouse: ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=92.0, Expect=5e-19]; ENSMUSG00000055632, Hmcn2, hemicentin 2, [Score=88.6, Expect=6e-18]} {Dmel: FBgn0000071, Ama, Amalgam, [RH, Score=111, Expect=7e-27]} {Celegans: WBGene00004372, rig-5, NeuRonal IGCAM, [RH, Score=98.2, Expect=6e-22]} {Smed: dd_Smed_v6_1161_0_1, dd_Smed_v6_1161_0_1, [Score=64.3, Expect=1e-10]} {RNA1310_49122} {RNA815_40619}
84. MligTC455_39804 351 7.32 Mlig455_026117, Mlig455_026177

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.434

0.953 - - - - - 0.953

Mlig455_026117 {REF} {Length: 1701} {Pfam: Immunoglobulin domain [PF13927.8, score=48.1]; Immunoglobulin I-set domain [PF07679.18, score=47.3]; Immunoglobulin domain [PF00047.27, score=33.0]; Immunoglobulin V-set domain [PF07686.19, score=30.6]} {Dmel: FBgn0037993, dpr15, defective proboscis extension response 15, [RH, Score=52.8, Expect=3e-07]} {Smed: dd_Smed_v6_22736_0_1, dd_Smed_v6_22736_0_1, [RH, Score=73.9, Expect=1e-14]} {RNA1310_21460} {RNA815_8845.1}

Mlig455_026177 {REF} {Length: 1111} {Pfam: Immunoglobulin domain [PF13927.8, score=41.5]; Immunoglobulin I-set domain [PF07679.18, score=39.2]; Immunoglobulin domain [PF00047.27, score=26.5]; Immunoglobulin V-set domain [PF07686.19, score=23.8]} {Dmel: FBgn0267428, CG45781, [Score=50.1, Expect=2e-06]} {Smed: dd_Smed_v6_22736_0_1, dd_Smed_v6_22736_0_1, [Score=67.8, Expect=1e-12]} {RNA1310_21460} {RNA815_8845.1}
85. MligTC455_15700 381 7.93 Mlig455_029700

Neo: -

Age: -

NEK9 0.952 0.952 - - - - - Mlig455_029700 {REF} {Length: 3273} {Pfam: Protein kinase domain [PF00069.27, score=196.8]; Regulator of chromosome condensation (RCC1) repeat [PF00415.20, score=167.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=136.5]; Regulator of chromosome condensation (RCC1) repeat [PF13540.8, score=78.8]; Fungal protein kinase [PF17667.3, score=20.1]} {Human: ENSG00000119638, NEK9, NIMA related kinase 9, [RH, Score=743, Expect=0.0]} {Mouse: ENSMUSG00000034290, Nek9, NIMA (never in mitosis gene a)-related expressed kinase 9, [RH, Score=724, Expect=0.0]} {Dmel: FBgn0045980, niki, nimA-like kinase, [Score=308, Expect=2e-91]} {Celegans: WBGene00021461, nekl-1, NEK (NEver in mitosis Kinase) Like, [Score=355, Expect=3e-108]} {Smed: dd_Smed_v6_8692_0_1, dd_Smed_v6_8692_0_1, [RH, Score=576, Expect=0.0]} {RNA1509_4066} {RNA1310_4454, RNA1509_4066} {RNA1509_4066, RNA815_1625}
86. MligTC455_19547 11 0.23 Mlig455_068540

Neo: -

Age: -

CUBN 0.952 - - - - 0.952 - Mlig455_068540 {REF} {Length: 3105} {Pfam: CUB domain [PF00431.22, score=94.3]} {Human: ENSG00000107611, CUBN, cubilin, [Score=63.9, Expect=1e-09]} {Mouse: ENSMUSG00000026726, Cubn, cubilin (intrinsic factor-cobalamin receptor), [Score=64.3, Expect=5e-10]} {Dmel: FBgn0261262, CG42613, [Score=95.9, Expect=5e-20]} {Celegans: WBGene00010587, sol-2, SOL-2 protein; Suppressor Of Lurcher movement defect, [Score=105, Expect=6e-24]} {Smed: dd_Smed_v6_11447_0_1, dd_Smed_v6_11447_0_1, [Score=72.8, Expect=3e-13]} {RNA1310_54691}
87. MligTC455_38410 2496 52 Mlig455_025330

Neo: Irradiation

Age: logFC(26M/2M)=0.253

0.952 - - - - 0.952 - Mlig455_025330 {REF} {Length: 2607} {TRANSSPLICED} {Pfam: Family of unknown function (DUF6479) [PF20087.1, score=21.7]} {RNA1509_48002, RNA1509_58871} {RNA1310_2864, RNA1509_48002, RNA1509_58871} {RNA1509_48002, RNA1509_58871, RNA815_8620}
88. MligTC455_40406 59 1.23 Mlig455_062481

Neo: -

Age: -

CHRNA9 0.952 - - - - 0.952 - Mlig455_062481 {REF} {Length: 3660} {TRANSSPLICED} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=153.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=111.8]} {Human: ENSG00000174343, CHRNA9, cholinergic receptor nicotinic alpha 9 subunit, [Score=205, Expect=2e-59]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=201, Expect=1e-57]; ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=201, Expect=7e-58]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=201, Expect=2e-57]; ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=201, Expect=1e-57]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=199, Expect=2e-57]; ENSG00000169684, CHRNA5, cholinergic receptor nicotinic alpha 5 subunit, [Score=199, Expect=4e-57]; ENSG00000101204, CHRNA4, cholinergic receptor nicotinic alpha 4 subunit, [Score=196, Expect=1e-54]} {Mouse: ENSMUSG00000029205, Chrna9, cholinergic receptor, nicotinic, alpha polypeptide 9, [Score=209, Expect=4e-61]; ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=207, Expect=7e-60]; ENSMUSG00000035594, Chrna5, cholinergic receptor, nicotinic, alpha polypeptide 5, [Score=200, Expect=6e-58]} {Dmel: FBgn0032151, nAChRalpha6, nicotinic Acetylcholine Receptor alpha6, [Score=202, Expect=2e-58]} {Celegans: WBGene00000050, acr-11, AcetylCholine Receptor, [Score=192, Expect=7e-55]} {Smed: dd_Smed_v6_9503_0_1, dd_Smed_v6_9503_0_1, [RH, Score=449, Expect=5e-153]} {RNA1509_18288} {RNA1310_3728, RNA1509_18288} {RNA1509_18288, RNA815_3826.3}
89. MligTC455_46583 1098 22.87 Mlig455_067509

Neo: -

Age: logFC(26M/2M)=-0.318

Region-enriched R8: 2.830/0.00000
Region-enriched R7: 1.613/0.00085

Regeneration-depleted TP: -3.677
Regeneration-depleted BL: -2.763
Regeneration-depleted R4: -2.132
Regeneration-depleted R2: -1.934

0.952 - - - - 0.952 - Mlig455_067509 {REF} {Length: 1536} {Pfam: Low-density lipoprotein receptor domain class A [PF00057.20, score=25.3]} {Dmel: FBgn0051221, CG31221, [Score=62.8, Expect=5e-12]} {Celegans: WBGene00010290, F58H1.7, [RH, Score=66.6, Expect=1e-13]} {Smed: dd_Smed_v6_2598_0_1, dd_Smed_v6_2598_0_1, [RH, Score=173, Expect=3e-55]} {RNA1509_59060} {RNA1310_28256} {RNA815_15141.1}
90. MligTC455_47217 532 11.09 Mlig455_006553

Neo: -

Age: -

LRRC34 0.952 - - - - - 0.952 Mlig455_006553 {REF} {Length: 2596} {TRANSSPLICED} {Pfam: Leucine Rich repeat [PF13516.8, score=104.4]; Leucine Rich repeats (2 copies) [PF12799.9, score=23.5]; Leucine Rich Repeat [PF00560.35, score=22.3]; Leucine rich repeat [PF13855.8, score=20.8]} {Human: ENSG00000171757, LRRC34, leucine rich repeat containing 34, [RH, Score=283, Expect=2e-91]} {Mouse: ENSMUSG00000027702, Lrrc34, leucine rich repeat containing 34, [RH, Score=336, Expect=3e-112]} {Dmel: FBgn0033369, CG8197, [RH, Score=58.2, Expect=5e-09]} {Celegans: WBGene00009201, F28C1.3, Protein phosphatase 1 regulatory subunit 37 homolog, [Score=53.1, Expect=3e-07]} {Smed: dd_Smed_v6_9926_1_1, dd_Smed_v6_9926_1_1, [RH, Score=382, Expect=1e-130]} {RNA1509_9806} {RNA1310_21676.1, RNA1509_9806} {RNA1509_9806, RNA815_6669}
91. MligTC455_53801 637 13.26 Mlig455_053844

Neo: -

Age: Down-Up-Down

FAM57A 0.952 - - - 0.952 - - Mlig455_053844 {REF} {Length: 7182} {Pfam: TLC domain [PF03798.18, score=87.8]} {Human: ENSG00000167695, FAM57A, family with sequence similarity 57 member A, [RH, Score=132, Expect=1e-36]} {Mouse: ENSMUSG00000069808, Fam57a, family with sequence similarity 57, member A, [RH, Score=138, Expect=2e-39]} {Dmel: FBgn0028480, CG17841, [Score=47.0, Expect=1e-05]} {RNA1509_25653, RNA1509_31292, RNA1509_31400, RNA1509_50854} {RNA1310_27304.1, RNA1509_25653, RNA1509_31292, RNA1509_31400, RNA1509_50854} {RNA1509_25653, RNA1509_31292, RNA1509_31400, RNA1509_50854, RNA815_15510}
92. MligTC455_17479 32 0.66 Mlig455_032081, Mlig455_070278

Neo: -

Age: logFC(26M/2M)=-0.516

CHRNA3 0.951 - - - - 0.951 -

Mlig455_032081 {REF} {Length: 2787} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=230.7]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=221.4]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=368, Expect=1e-121]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=366, Expect=5e-121]} {Mouse: ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=378, Expect=6e-126]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=361, Expect=3e-119]} {Dmel: FBgn0266347, nAChRalpha4, nicotinic Acetylcholine Receptor alpha4, [Score=461, Expect=3e-158]} {Celegans: WBGene00006797, unc-63, Acetylcholine receptor subunit alpha-type unc-63, [Score=381, Expect=3e-127]} {Smed: dd_Smed_v6_9799_0_1, dd_Smed_v6_9799_0_1, [Score=614, Expect=0.0]} {RNA1509_28642} {RNA1310_34709} {RNA815_44960}

Mlig455_070278 {REF} {Length: 2270} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=232.1]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=221.2]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=369, Expect=7e-122]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=366, Expect=4e-121]} {Mouse: ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=378, Expect=9e-126]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=362, Expect=1e-119]} {Dmel: FBgn0266347, nAChRalpha4, nicotinic Acetylcholine Receptor alpha4, [Score=461, Expect=3e-158]} {Celegans: WBGene00006797, unc-63, Acetylcholine receptor subunit alpha-type unc-63, [Score=382, Expect=2e-127]} {Smed: dd_Smed_v6_9799_0_1, dd_Smed_v6_9799_0_1, [Score=616, Expect=0.0]} {RNA1509_16247} {RNA1310_34709} {RNA815_44960}
93. MligTC455_46482 1477 30.77 Mlig455_029196

Neo: -

Age: -

Region-enriched R2: 1.080/0.01471

PLSCR1 0.951 - - - 0.951 - - Mlig455_029196 {REF} {Length: 1363} {Pfam: Scramblase [PF03803.17, score=27.8]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=42.0, Expect=9e-06]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=42.7, Expect=3e-06]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=41.2, Expect=1e-05]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=44.3, Expect=7e-07]} {RNA1509_6872} {RNA1310_19869.1} {RNA815_8634}
94. MligTC455_49793 54 1.12 Mlig455_000683, Mlig455_000735, Mlig455_034198

Neo: -

Age: -

KREMEN1 0.951 - - - - 0.951 -

Mlig455_000683 {REF} {Length: 1382} {Pfam: WSC domain [PF01822.21, score=48.5]; PAN-like domain [PF08277.14, score=21.1]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=53.1, Expect=5e-07]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=54.3, Expect=1e-07]} {RNA1310_39474.2} {RNA815_58746}

Mlig455_000735 {REF} {Length: 1490} {Pfam: WSC domain [PF01822.21, score=36.2]; PAN domain [PF00024.28, score=20.9]} {RNA1310_36702.1} {RNA815_58746}

Mlig455_034198 {REF} {Length: 685} {Pfam: WSC domain [PF01822.21, score=42.1]; PAN domain [PF00024.28, score=19.0]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=52.8, Expect=1e-07]} {RNA1310_148883} {RNA815_58746}
95. MligTC455_51867 238 4.97 Mlig455_051265

Neo: -

Age: -

NEK1 0.951 0.951 - - - - - Mlig455_051265 {REF} {Length: 5255} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=227.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=158.9]; Kinase-like [PF14531.8, score=26.1]; ABC1 atypical kinase-like domain [PF03109.18, score=24.4]} {Human: ENSG00000137601, NEK1, NIMA related kinase 1, [RH, Score=384, Expect=5e-113]} {Mouse: ENSMUSG00000031644, Nek1, NIMA (never in mitosis gene a)-related expressed kinase 1, [RH, Score=380, Expect=1e-111]} {Dmel: FBgn0045980, niki, nimA-like kinase, [Score=213, Expect=5e-57]} {Celegans: WBGene00021461, nekl-1, NEK (NEver in mitosis Kinase) Like, [Score=216, Expect=2e-57]} {Smed: dd_Smed_v6_11366_0_1, dd_Smed_v6_11366_0_1, [RH, Score=299, Expect=3e-84]} {RNA1509_27598} {RNA1310_1375.1} {RNA815_18404}
96. MligTC455_27307 18 0.38 Mlig455_040526

Neo: -

Age: -

0.95 - - - - 0.950 - Mlig455_040526 {REF} {Length: 3950} {RNA1509_53435} {RNA1310_34828.2} {RNA815_11419.1}
97. MligTC455_29261 34 0.71 Mlig455_024258

Neo: -

Age: -

0.95 - - - - 0.950 - Mlig455_024258 {REF} {Length: 1171} {RNA1509_25125} {RNA1310_234.1} {RNA815_23.1}
98. MligTC455_47698 54 1.13 Mlig455_025417

Neo: -

Age: -

ADRA2A 0.95 - - - - 0.950 - Mlig455_025417 {REF} {Length: 1772} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=263.1]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=33.1]; Olfactory receptor [PF13853.8, score=25.8]} {Human: ENSG00000150594, ADRA2A, adrenoceptor alpha 2A, [Score=267, Expect=3e-85]; ENSG00000178394, HTR1A, 5-hydroxytryptamine receptor 1A, [Score=258, Expect=4e-82]} {Mouse: ENSMUSG00000033717, Adra2a, adrenergic receptor, alpha 2a, [Score=273, Expect=9e-88]} {Dmel: FBgn0038653, CG18208, [Score=222, Expect=3e-66]} {Celegans: WBGene00006411, octr-1, OCTopamine Receptor (GPCR), [Score=272, Expect=2e-88]} {Smed: dd_Smed_v6_48706_0_1, dd_Smed_v6_48706_0_1, [RH, Score=323, Expect=1e-108]} {RNA1310_113575}
99. MligTC455_48302 45 0.93 Mlig455_056275

Neo: -

Age: -

CHRNA7 0.95 - - - - 0.950 - Mlig455_056275 {REF} {Length: 3506} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=176.6]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=131.0]} {Human: ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=255, Expect=4e-76]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=251, Expect=5e-75]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=250, Expect=2e-74]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=245, Expect=6e-73]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=237, Expect=7e-70]; ENSMUSG00000029205, Chrna9, cholinergic receptor, nicotinic, alpha polypeptide 9, [Score=234, Expect=6e-69]} {Dmel: FBgn0266347, nAChRalpha4, nicotinic Acetylcholine Receptor alpha4, [Score=271, Expect=1e-82]} {Celegans: WBGene00006797, unc-63, Acetylcholine receptor subunit alpha-type unc-63, [Score=254, Expect=1e-76]} {Smed: dd_Smed_v6_18201_0_1, dd_Smed_v6_18201_0_1, [Score=471, Expect=8e-158]} {RNA1509_49660} {RNA1310_35095} {RNA815_30373}
100. MligTC455_54106 87 1.81 Mlig455_046338, Mlig455_068234

Neo: Int S/G2/M

Age: Up-Down-Down

PLCB1, PLCB3 0.95 - - - - 0.950 -

Mlig455_046338 {REF} {Length: 4577} {Pfam: Phosphatidylinositol-specific phospholipase C, X domain [PF00388.21, score=201.8]; Phosphatidylinositol-specific phospholipase C, Y domain [PF00387.21, score=127.9]; PH domain [PF17787.3, score=69.3]; Protein of unknown function (DUF1154) [PF06631.13, score=28.5]; Phosphoinositide-specific phospholipase C, efhand-like [PF09279.13, score=27.5]} {Human: ENSG00000182621, PLCB1, phospholipase C beta 1, [Score=797, Expect=0.0]; ENSG00000149782, PLCB3, phospholipase C beta 3, [Score=796, Expect=0.0]} {Mouse: ENSMUSG00000051177, Plcb1, phospholipase C, beta 1, [Score=801, Expect=0.0]; ENSMUSG00000024960, Plcb3, phospholipase C, beta 3, [Score=784, Expect=0.0]} {Dmel: FBgn0004611, Plc21C, Phospholipase C at 21C, [Score=418, Expect=4e-125]} {Celegans: WBGene00001177, egl-8, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8, [Score=671, Expect=0.0]} {Smed: dd_Smed_v6_3221_0_1, dd_Smed_v6_3221_0_1, [Score=702, Expect=0.0]} {RNA1509_50989} {RNA1310_17477} {RNA815_25811}

Mlig455_068234 {REF} {Length: 4646} {Pfam: Phosphatidylinositol-specific phospholipase C, X domain [PF00388.21, score=201.7]; Phosphatidylinositol-specific phospholipase C, Y domain [PF00387.21, score=127.9]; PH domain [PF17787.3, score=123.2]; Protein of unknown function (DUF1154) [PF06631.13, score=28.5]; Phosphoinositide-specific phospholipase C, efhand-like [PF09279.13, score=27.4]} {Human: ENSG00000149782, PLCB3, phospholipase C beta 3, [RH, Score=837, Expect=0.0]; ENSG00000182621, PLCB1, phospholipase C beta 1, [RH, Score=831, Expect=0.0]} {Mouse: ENSMUSG00000051177, Plcb1, phospholipase C, beta 1, [RH, Score=830, Expect=0.0]; ENSMUSG00000024960, Plcb3, phospholipase C, beta 3, [RH, Score=827, Expect=0.0]} {Dmel: FBgn0004611, Plc21C, Phospholipase C at 21C, [Score=444, Expect=7e-134]} {Celegans: WBGene00001177, egl-8, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8, [Score=684, Expect=0.0]} {Smed: dd_Smed_v6_3221_0_2, dd_Smed_v6_3221_0_2, [Score=716, Expect=0.0]} {RNA1509_50989} {RNA1310_17477, RNA1509_50989} {RNA1509_50989, RNA815_25811}

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