Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_34724 | 4929 | 102.68 | Mlig455_029265 | Neo: Int S/G2/M Age: logFC(26M/2M)=0.253 |
IGF2BP1 | Mlig455_029265 {REF} {Length: 1871} {TRANSSPLICED} {Pfam: KH domain [PF00013.31, score=103.7]; KH domain [PF07650.19, score=36.6]; KH domain [PF13083.8, score=33.4]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=27.1]} {Human: ENSG00000159217, IGF2BP1, insulin like growth factor 2 mRNA binding protein 1, [RH, Score=125, Expect=5e-31]; ENSG00000073792, IGF2BP2, insulin like growth factor 2 mRNA binding protein 2, [RH, Score=123, Expect=2e-30]} {Mouse: ENSMUSG00000013415, Igf2bp1, insulin-like growth factor 2 mRNA binding protein 1, [RH, Score=129, Expect=1e-32]; ENSMUSG00000033581, Igf2bp2, insulin-like growth factor 2 mRNA binding protein 2, [RH, Score=125, Expect=1e-31]} {Dmel: FBgn0285926, Imp, IGF-II mRNA-binding protein, [Score=143, Expect=1e-37]} {Celegans: WBGene00010908, zbp-1, Zipcode Binding Protein homolog, [RH, Score=87.0, Expect=2e-18]} {Smed: dd_Smed_v6_3047_0_1, dd_Smed_v6_3047_0_1, [Score=154, Expect=2e-41]} {RNA1509_15136, RNA1509_15998, RNA1509_21756, RNA1509_3179} {RNA1310_15501.1, RNA1509_15136, RNA1509_15998, RNA1509_21756, RNA1509_3179} {RNA1509_15136, RNA1509_15998, RNA1509_21756, RNA1509_3179, RNA815_7080.1} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -1.652 | 6.828 | 0.00155 | 0.13052 | |
RegionR2 | -0.071 | 6.828 | 0.72904 | 1.00000 | |
RegionR3 | 0.032 | 6.828 | 0.84707 | 1.00000 | |
RegionR4 | 0.354 | 6.828 | 0.05261 | 0.19963 | |
RegionR5 | 0.721 | 6.828 | 0.00000 | 0.00003 | |
RegionR6 | 0.349 | 6.828 | 0.03366 | 0.34195 | |
RegionR7 | 0.175 | 6.828 | 0.40012 | 1.00000 | |
RegionR8 | 0.092 | 6.828 | 0.72553 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -0.676 | 6.828 | 0.45263 | 1.00000 | |
RegenerationR2 | 0.006 | 6.828 | 0.97271 | 1.00000 | |
RegenerationR3 | -0.04 | 6.828 | 0.82287 | 0.98863 | |
RegenerationR4 | -0.342 | 6.828 | 0.05174 | 0.36588 | |
RegenerationR5 | -0.296 | 6.828 | 0.06984 | 0.41500 | |
RegenerationR6 | -0.021 | 6.828 | 0.90298 | 1.00000 | |
RegenerationBL | 0.386 | 6.828 | 0.04286 | 0.23603 | |
RegenerationTP | 0.066 | 6.828 | 0.76656 | 1.00000 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_34724 | 4929 | 102.68 | Mlig455_029265 | Neo: Int S/G2/M Age: logFC(26M/2M)=0.253 |
IGF2BP1 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_029265 {REF} {Length: 1871} {TRANSSPLICED} {Pfam: KH domain [PF00013.31, score=103.7]; KH domain [PF07650.19, score=36.6]; KH domain [PF13083.8, score=33.4]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=27.1]} {Human: ENSG00000159217, IGF2BP1, insulin like growth factor 2 mRNA binding protein 1, [RH, Score=125, Expect=5e-31]; ENSG00000073792, IGF2BP2, insulin like growth factor 2 mRNA binding protein 2, [RH, Score=123, Expect=2e-30]} {Mouse: ENSMUSG00000013415, Igf2bp1, insulin-like growth factor 2 mRNA binding protein 1, [RH, Score=129, Expect=1e-32]; ENSMUSG00000033581, Igf2bp2, insulin-like growth factor 2 mRNA binding protein 2, [RH, Score=125, Expect=1e-31]} {Dmel: FBgn0285926, Imp, IGF-II mRNA-binding protein, [Score=143, Expect=1e-37]} {Celegans: WBGene00010908, zbp-1, Zipcode Binding Protein homolog, [RH, Score=87.0, Expect=2e-18]} {Smed: dd_Smed_v6_3047_0_1, dd_Smed_v6_3047_0_1, [Score=154, Expect=2e-41]} {RNA1509_15136, RNA1509_15998, RNA1509_21756, RNA1509_3179} {RNA1310_15501.1, RNA1509_15136, RNA1509_15998, RNA1509_21756, RNA1509_3179} {RNA1509_15136, RNA1509_15998, RNA1509_21756, RNA1509_3179, RNA815_7080.1} |
2. | MligTC455_34725 | 4163 | 86.73 | Mlig455_035650 | Neo: Int S/G2/M Age: - |
IGF2BP1 | 5.257 | 0.841 | 0.752 | 0.895 | 0.932 | 0.983 | 0.854 | Mlig455_035650 {REF} {Length: 1870} {TRANSSPLICED} {Pfam: KH domain [PF00013.31, score=100.9]; KH domain [PF07650.19, score=36.7]; KH domain [PF13083.8, score=33.9]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=26.4]} {Human: ENSG00000159217, IGF2BP1, insulin like growth factor 2 mRNA binding protein 1, [RH, Score=128, Expect=4e-32]} {Mouse: ENSMUSG00000013415, Igf2bp1, insulin-like growth factor 2 mRNA binding protein 1, [RH, Score=130, Expect=6e-33]} {Dmel: FBgn0285926, Imp, IGF-II mRNA-binding protein, [Score=142, Expect=2e-37]} {Celegans: WBGene00010908, zbp-1, Zipcode Binding Protein homolog, [RH, Score=86.3, Expect=4e-18]} {Smed: dd_Smed_v6_3047_0_1, dd_Smed_v6_3047_0_1, [Score=157, Expect=3e-42]} {RNA1509_1913} {RNA1310_15501.1, RNA1509_1913} {RNA1509_1913, RNA815_7080.1} |
3. | MligTC455_47744 | 3571 | 74.4 | Mlig455_009832, Mlig455_010352 | Neo: - Age: - |
MAP2K6 | 2.567 | - | - | 0.792 | 0.825 | 0.950 | - | Mlig455_009832 {REF} {Length: 1615} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=179.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=111.9]; Kinase-like [PF14531.8, score=25.8]; ABC1 atypical kinase-like domain [PF03109.18, score=18.0]} {Human: ENSG00000108984, MAP2K6, mitogen-activated protein kinase kinase 6, [Score=243, Expect=4e-78]; ENSG00000034152, MAP2K3, mitogen-activated protein kinase kinase 3, [Score=235, Expect=6e-75]} {Mouse: ENSMUSG00000020623, Map2k6, mitogen-activated protein kinase kinase 6, [Score=242, Expect=5e-78]; ENSMUSG00000018932, Map2k3, mitogen-activated protein kinase kinase 3, [Score=233, Expect=1e-74]} {Dmel: FBgn0261524, lic, licorne, [Score=228, Expect=9e-73]} {Celegans: WBGene00004758, sek-1, Dual specificity mitogen-activated protein kinase kinase sek-1, [Score=233, Expect=8e-75]} {Smed: dd_Smed_v6_2106_0_1, dd_Smed_v6_2106_0_1, [Score=224, Expect=2e-71]} {RNA1509_18627, RNA1509_27275} {RNA1310_19035.2, RNA1509_18627, RNA1509_27275} {RNA1509_18627, RNA1509_27275, RNA815_3018.1} Mlig455_010352 {REF} {Length: 1636} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=178.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=112.6]; Kinase-like [PF14531.8, score=25.8]; ABC1 atypical kinase-like domain [PF03109.18, score=18.0]} {Human: ENSG00000108984, MAP2K6, mitogen-activated protein kinase kinase 6, [Score=241, Expect=1e-77]; ENSG00000034152, MAP2K3, mitogen-activated protein kinase kinase 3, [Score=234, Expect=2e-74]} {Mouse: ENSMUSG00000020623, Map2k6, mitogen-activated protein kinase kinase 6, [Score=241, Expect=2e-77]; ENSMUSG00000018932, Map2k3, mitogen-activated protein kinase kinase 3, [Score=232, Expect=4e-74]} {Dmel: FBgn0261524, lic, licorne, [Score=226, Expect=7e-72]} {Celegans: WBGene00004758, sek-1, Dual specificity mitogen-activated protein kinase kinase sek-1, [Score=232, Expect=3e-74]} {Smed: dd_Smed_v6_2106_0_1, dd_Smed_v6_2106_0_1, [Score=228, Expect=1e-72]} {RNA1509_28594, RNA1509_35327} {RNA1310_19035.1, RNA1509_28594, RNA1509_35327} {RNA1509_28594, RNA1509_35327, RNA815_3018.1} |
4. | MligTC455_47969 | 1640 | 34.16 | Mlig455_036234 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=0.600 Region-enriched R5: 1.638/0.00000 |
NMT2 | 2.561 | - | - | 0.744 | 0.981 | 0.836 | - | Mlig455_036234 {REF} {Length: 1943} {TRANSSPLICED} {Pfam: Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain [PF01233.21, score=252.7]; Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain [PF02799.17, score=233.5]; Acetyltransferase (GNAT) domain [PF13527.9, score=20.6]; Acetyltransferase (GNAT) family [PF00583.27, score=19.6]} {Human: ENSG00000152465, NMT2, N-myristoyltransferase 2, [RH, Score=510, Expect=1e-178]; ENSG00000136448, NMT1, N-myristoyltransferase 1, [RH, Score=501, Expect=5e-175]} {Mouse: ENSMUSG00000026643, Nmt2, N-myristoyltransferase 2, [RH, Score=514, Expect=2e-180]; ENSMUSG00000020936, Nmt1, N-myristoyltransferase 1, [RH, Score=503, Expect=6e-176]} {Dmel: FBgn0020392, Nmt, N-myristoyl transferase, [RH, Score=505, Expect=3e-177]} {Celegans: WBGene00020549, nmt-1, Probable glycylpeptide N-tetradecanoyltransferase, [RH, Score=455, Expect=3e-158]} {Smed: dd_Smed_v6_1145_0_1, dd_Smed_v6_1145_0_1, [RH, Score=489, Expect=1e-171]} {RNA1509_16947, RNA1509_27240, RNA1509_5138} {RNA1310_13485.1, RNA1509_16947, RNA1509_27240} {RNA1509_16947, RNA1509_27240, RNA815_5317} |
5. | MligTC455_44888 | 1432 | 29.83 | Mlig455_018517 | Neo: - Age: - Region-enriched R8: 1.419/0.01908 |
LGR6 | 1.726 | - | - | - | 0.763 | 0.963 | - | Mlig455_018517 {REF} {Length: 3076} {Pfam: Leucine rich repeat [PF13855.8, score=105.2]; Leucine Rich repeats (2 copies) [PF12799.9, score=62.5]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=30.2]; Leucine-rich repeat [PF14580.8, score=21.2]; Leucine Rich Repeat [PF00560.35, score=19.2]} {Human: ENSG00000133067, LGR6, leucine rich repeat containing G protein-coupled receptor 6, [Score=77.8, Expect=3e-14]; ENSG00000099769, IGFALS, insulin like growth factor binding protein acid labile subunit, [Score=76.6, Expect=6e-14]; ENSG00000131409, LRRC4B, leucine rich repeat containing 4B, [Score=75.9, Expect=1e-13]} {Mouse: ENSMUSG00000050199, Lgr4, leucine-rich repeat-containing G protein-coupled receptor 4, [Score=75.9, Expect=9e-14]; ENSMUSG00000047085, Lrrc4b, leucine rich repeat containing 4B, [Score=75.5, Expect=1e-13]; ENSMUSG00000020105, Lrig3, leucine-rich repeats and immunoglobulin-like domains 3, [Score=72.8, Expect=9e-13]} {Dmel: FBgn0023095, caps, capricious, [Score=73.9, Expect=2e-13]} {Celegans: WBGene00020649, sma-10, Leucine-rich repeats and immunoglobulin-like domains protein sma-10, [Score=74.7, Expect=1e-13]} {Smed: dd_Smed_v6_2769_0_1, dd_Smed_v6_2769_0_1, [Score=105, Expect=1e-23]} {RNA1509_8972} {RNA1310_3884.2, RNA1509_8972} {RNA1509_8972, RNA815_1780} |
6. | MligTC455_37852 | 1256 | 26.17 | Mlig455_070559 | Neo: - Age: Up-Down-Down |
1.68 | 0.724 | - | - | 0.956 | - | - | Mlig455_070559 {REF} {Length: 3472} {RNA1509_21553, RNA1509_32227, RNA1509_52243} {RNA1310_34347, RNA1509_21553, RNA1509_32227, RNA1509_52243} {RNA1509_21553, RNA1509_32227, RNA1509_52243, RNA815_13962} | |
7. | MligTC455_35998 | 1012 | 21.09 | Mlig455_017147 | Neo: - Age: - Regeneration-upregulated BL: 1.812 Regeneration-enriched BL: 1.812 |
DOT1L | 1.678 | - | - | - | 0.721 | 0.957 | - | Mlig455_017147 {REF} {Length: 2954} {Pfam: Histone methylation protein DOT1 [PF08123.15, score=243.1]} {Human: ENSG00000104885, DOT1L, DOT1 like histone lysine methyltransferase, [RH, Score=371, Expect=1e-112]} {Mouse: ENSMUSG00000061589, Dot1l, DOT1-like, histone H3 methyltransferase (S. cerevisiae), [RH, Score=352, Expect=6e-106]} {Dmel: FBgn0264495, gpp, grappa, [RH, Score=342, Expect=5e-102]} {Celegans: WBGene00021474, dot-1.1, DOT1 histone methyltransferase family, [RH, Score=162, Expect=2e-41]} {Smed: dd_Smed_v6_4515_0_3, dd_Smed_v6_4515_0_3, [RH, Score=361, Expect=4e-115]} {RNA1509_3518} {RNA1310_219} {RNA815_1960} |
8. | MligTC455_37851 | 1246 | 25.95 | Mlig455_070540 | Neo: - Age: Down-Up-Down |
1.678 | 0.719 | - | - | 0.959 | - | - | Mlig455_070540 {REF} {Length: 1184} {NoTransDecoderORF} {RNA1509_32227} {RNA1310_34347} {RNA815_13962} | |
9. | MligTC455_10949 | 2342 | 48.79 | Mlig455_034538 | Neo: - Age: - Region-enriched R4: 1.038/0.01693 |
ARPC5 | 0.966 | - | - | - | - | 0.966 | - | Mlig455_034538 {REF} {Length: 1904} {TRANSSPLICED} {Pfam: ARP2/3 complex 16 kDa subunit (p16-Arc) [PF04699.16, score=141.1]; Dip2/Utp12 Family [PF04003.14, score=24.4]} {Human: ENSG00000162704, ARPC5, actin related protein 2/3 complex subunit 5, [RH, Score=138, Expect=4e-42]} {Mouse: ENSMUSG00000008475, Arpc5, actin related protein 2/3 complex, subunit 5, [RH, Score=138, Expect=4e-42]} {Dmel: FBgn0031437, Arpc5, Actin-related protein 2/3 complex, subunit 5, [RH, Score=124, Expect=9e-37]} {Celegans: WBGene00000205, arx-7, Actin-related protein 2/3 complex subunit 5, [RH, Score=88.6, Expect=6e-23]} {Smed: dd_Smed_v6_781_0_1, dd_Smed_v6_781_0_1, [RH, Score=103, Expect=6e-29]} {RNA1509_3008, RNA1509_4650} {RNA1310_34556, RNA1509_3008} {RNA1509_3008, RNA815_15796.1} |
10. | MligTC455_04176 | 877 | 18.27 | Mlig455_054450 | Neo: - Age: - |
CNNM2 | 0.962 | - | - | - | - | 0.962 | - | Mlig455_054450 {REF} {Length: 4443} {TRANSSPLICED} {Pfam: Cyclin M transmembrane N-terminal domain [PF01595.22, score=110.9]; CBS domain [PF00571.30, score=29.5]} {Human: ENSG00000148842, CNNM2, cyclin and CBS domain divalent metal cation transport mediator 2, [RH, Score=397, Expect=3e-125]; ENSG00000158158, CNNM4, cyclin and CBS domain divalent metal cation transport mediator 4, [RH, Score=387, Expect=4e-122]} {Mouse: ENSMUSG00000064105, Cnnm2, cyclin M2, [RH, Score=396, Expect=5e-125]; ENSMUSG00000037408, Cnnm4, cyclin M4, [RH, Score=384, Expect=3e-121]} {Dmel: FBgn0262124, uex, unextended, [RH, Score=402, Expect=2e-127]} {Celegans: WBGene00016879, cnnm-1, Metal transporter cnnm-1, [RH, Score=299, Expect=5e-89]} {Smed: dd_Smed_v6_6903_0_1, dd_Smed_v6_6903_0_1, [RH, Score=419, Expect=1e-134]} {RNA1509_33003, RNA1509_9183} {RNA1310_7581.1, RNA1509_33003} {RNA1509_33003, RNA815_1409.1} |
11. | MligTC455_42707 | 490 | 10.2 | Mlig455_062703 | Neo: - Age: Up-Up-Down |
0.957 | - | - | - | 0.957 | - | - | Mlig455_062703 {REF} {Length: 1072} {RNA1509_18300} {RNA1310_42056} {RNA815_25547} |