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Results for MligTC455_35410

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_35410 528 11.00 Mlig455_064178

Neo: -

Age: Down-Down-Down

Region-enriched R2: 2.241/0.03122

PPP3CA Mlig455_064178 {REF} {Length: 4178} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=129.2]} {Human: ENSG00000138814, PPP3CA, protein phosphatase 3 catalytic subunit alpha, [Score=701, Expect=0.0]; ENSG00000107758, PPP3CB, protein phosphatase 3 catalytic subunit beta, [Score=690, Expect=0.0]; ENSG00000120910, PPP3CC, protein phosphatase 3 catalytic subunit gamma, [Score=673, Expect=0.0]} {Mouse: ENSMUSG00000028161, Ppp3ca, protein phosphatase 3, catalytic subunit, alpha isoform, [Score=703, Expect=0.0]; ENSMUSG00000021816, Ppp3cb, protein phosphatase 3, catalytic subunit, beta isoform, [Score=690, Expect=0.0]} {Dmel: FBgn0267912, CanA-14F, Calcineurin A at 14F, [Score=697, Expect=0.0]} {Celegans: WBGene00006527, tax-6, Serine/threonine-protein phosphatase 2B catalytic subunit, [Score=646, Expect=0.0]} {Smed: dd_Smed_v6_5378_0_1, dd_Smed_v6_5378_0_1, [Score=523, Expect=0.0]} {RNA1509_25279} {RNA1310_17931} {RNA815_6996}

Cumulative graph for MligTC455_35410

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -6.672 3.824 0.06247 0.57054
RegionR2 2.241 3.824 0.00170 0.03122
RegionR3 0.679 3.824 0.43265 0.95170
RegionR4 0.131 3.824 0.79881 1.00000
RegionR5 0.077 3.824 0.81833 1.00000
RegionR6 0.584 3.824 0.51138 1.00000
RegionR7 1.281 3.824 0.12478 0.66530
RegionR8 1.679 3.824 0.06825 0.50176

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 6.196 3.824 0.15440 0.89657
RegenerationR2 -0.574 3.824 0.19820 0.64343
RegenerationR3 -0.616 3.824 0.25061 0.68504
RegenerationR4 0.085 3.824 0.88289 1.00000
RegenerationR5 -0.399 3.824 0.45342 0.83251
RegenerationR6 -0.929 3.824 0.10348 0.39853
RegenerationBL -1.29 3.824 0.04433 0.24080
RegenerationTP -1.547 3.824 0.02355 0.26009


Genes with expression patterns similar to MligTC455_35410

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_35410 528 11 Mlig455_064178

Neo: -

Age: Down-Down-Down

Region-enriched R2: 2.241/0.03122

PPP3CA 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_064178 {REF} {Length: 4178} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=129.2]} {Human: ENSG00000138814, PPP3CA, protein phosphatase 3 catalytic subunit alpha, [Score=701, Expect=0.0]; ENSG00000107758, PPP3CB, protein phosphatase 3 catalytic subunit beta, [Score=690, Expect=0.0]; ENSG00000120910, PPP3CC, protein phosphatase 3 catalytic subunit gamma, [Score=673, Expect=0.0]} {Mouse: ENSMUSG00000028161, Ppp3ca, protein phosphatase 3, catalytic subunit, alpha isoform, [Score=703, Expect=0.0]; ENSMUSG00000021816, Ppp3cb, protein phosphatase 3, catalytic subunit, beta isoform, [Score=690, Expect=0.0]} {Dmel: FBgn0267912, CanA-14F, Calcineurin A at 14F, [Score=697, Expect=0.0]} {Celegans: WBGene00006527, tax-6, Serine/threonine-protein phosphatase 2B catalytic subunit, [Score=646, Expect=0.0]} {Smed: dd_Smed_v6_5378_0_1, dd_Smed_v6_5378_0_1, [Score=523, Expect=0.0]} {RNA1509_25279} {RNA1310_17931} {RNA815_6996}
2. MligTC455_35411 583 12.15 Mlig455_064235

Neo: -

Age: -

PPP3CA 4.094 0.817 0.789 0.704 0.950 0.834 - Mlig455_064235 {REF} {Length: 3595} {Human: ENSG00000138814, PPP3CA, protein phosphatase 3 catalytic subunit alpha, [Score=156, Expect=8e-46]; ENSG00000107758, PPP3CB, protein phosphatase 3 catalytic subunit beta, [Score=149, Expect=4e-43]} {Mouse: ENSMUSG00000028161, Ppp3ca, protein phosphatase 3, catalytic subunit, alpha isoform, [Score=158, Expect=1e-46]} {Dmel: FBgn0011826, Pp2B-14D, Protein phosphatase 2B at 14D, [Score=159, Expect=1e-46]} {Celegans: WBGene00006527, tax-6, Serine/threonine-protein phosphatase 2B catalytic subunit, [Score=115, Expect=1e-30]} {Smed: dd_Smed_v6_5669_1_2, dd_Smed_v6_5669_1_2, [Score=155, Expect=7e-49]} {RNA1509_42566} {RNA1310_30586} {RNA815_21103.2}
3. MligTC455_18564 196 4.08 Mlig455_063527

Neo: -

Age: -

Region-enriched R2: 2.416/0.01839

PRKG2 3.462 0.834 - - 0.958 0.771 0.899 Mlig455_063527 {REF} {Length: 2971} {Pfam: Protein kinase domain [PF00069.27, score=212.4]; Cyclic nucleotide-binding domain [PF00027.31, score=135.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=103.7]; Kinase-like [PF14531.8, score=24.8]} {Human: ENSG00000138669, PRKG2, protein kinase cGMP-dependent 2, [RH, Score=653, Expect=0.0]} {Mouse: ENSMUSG00000029334, Prkg2, protein kinase, cGMP-dependent, type II, [RH, Score=651, Expect=0.0]} {Dmel: FBgn0000442, Pkg21D, Protein kinase, cGMP-dependent at 21D, [RH, Score=662, Expect=0.0]} {Celegans: WBGene00001173, egl-4, cGMP-dependent protein kinase egl-4, [Score=655, Expect=0.0]} {Smed: dd_Smed_v6_6967_0_1, dd_Smed_v6_6967_0_1, [RH, Score=645, Expect=0.0]} {RNA1509_38353} {RNA1310_8466, RNA1509_38353} {RNA1509_38353, RNA815_6313}
4. MligTC455_53504 217 4.51 Mlig455_037385

Neo: -

Age: -

Region-enriched R2: 3.142/0.00738

CSMD1 3.4 - - 0.715 0.969 0.797 0.919 Mlig455_037385 {REF} {Length: 2214} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=198.7]} {Human: ENSG00000183117, CSMD1, CUB and Sushi multiple domains 1, [Score=149, Expect=8e-37]} {Mouse: ENSMUSG00000028369, Svep1, sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1, [Score=136, Expect=7e-33]; ENSMUSG00000060924, Csmd1, CUB and Sushi multiple domains 1, [Score=134, Expect=5e-32]; ENSMUSG00000022311, Csmd3, CUB and Sushi multiple domains 3, [Score=133, Expect=9e-32]} {Dmel: FBgn0032797, Hasp, Hig-anchoring scaffold protein, [RH, Score=218, Expect=3e-60]} {Celegans: WBGene00002976, lev-9, [RH, Score=244, Expect=4e-72]} {Smed: dd_Smed_v6_13071_0_1, dd_Smed_v6_13071_0_1, [RH, Score=296, Expect=1e-91]} {RNA1509_55985} {RNA1310_12867.1, RNA1509_55985} {RNA1509_55985, RNA815_9157}
5. MligTC455_44120 125 2.61 Mlig455_041513

Neo: -

Age: Up-Down-Down

Region-enriched R2: 7.169/0.00020

3.344 - - 0.760 0.952 0.764 0.868 Mlig455_041513 {REF} {Length: 644} {NoTransDecoderORF} {RNA1310_39164} {RNA815_4344}
6. MligTC455_54231 270 5.62 Mlig455_059344

Neo: -

Age: logFC(26M/2M)=-0.427

2.637 - - 0.860 0.989 - 0.788 Mlig455_059344 {REF} {Length: 1419} {RNA1310_28936} {RNA815_10014.1}
7. MligTC455_05889 28 0.58 Mlig455_027604, Mlig455_047689, Mlig455_047690

Neo: -

Age: -

TLR4 2.609 - - - 0.959 0.753 0.897

Mlig455_027604 {REF} {Length: 3445} {Pfam: Leucine rich repeat [PF13855.8, score=68.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=38.2]; TIR domain [PF01582.22, score=31.9]; TIR domain [PF13676.8, score=24.5]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=21.4]} {Human: ENSG00000136869, TLR4, toll like receptor 4, [RH, Score=74.3, Expect=6e-13]} {Mouse: ENSMUSG00000031558, Slit2, slit guidance ligand 2, [Score=60.1, Expect=1e-08]; ENSMUSG00000030600, Lrfn1, leucine rich repeat and fibronectin type III domain containing 1, [Score=59.3, Expect=2e-08]; ENSMUSG00000056427, Slit3, slit guidance ligand 3, [Score=58.5, Expect=4e-08]} {Dmel: FBgn0036494, Toll-6, [Score=80.5, Expect=4e-15]} {Celegans: WBGene00006593, tol-1, TOLl (Drosophila) family, [Score=50.4, Expect=6e-06]} {RNA1310_7084} {RNA815_22808}

Mlig455_047689 {REF} {Length: 352} {Pfam: Leucine rich repeat [PF13855.8, score=35.5]; Leucine Rich repeats (2 copies) [PF12799.9, score=20.6]} {RNA1310_7084} {RNA815_47088}

Mlig455_047690 {REF} {Length: 346} {Pfam: Leucine rich repeat [PF13855.8, score=68.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=38.2]; TIR domain [PF01582.22, score=31.9]; TIR domain [PF13676.8, score=24.5]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=21.4]} {Human: ENSG00000136869, TLR4, toll like receptor 4, [RH, Score=74.3, Expect=6e-13]} {Mouse: ENSMUSG00000031558, Slit2, slit guidance ligand 2, [Score=60.1, Expect=1e-08]; ENSMUSG00000030600, Lrfn1, leucine rich repeat and fibronectin type III domain containing 1, [Score=59.3, Expect=2e-08]; ENSMUSG00000056427, Slit3, slit guidance ligand 3, [Score=58.5, Expect=4e-08]} {Dmel: FBgn0036494, Toll-6, [Score=80.5, Expect=4e-15]} {Celegans: WBGene00006593, tol-1, TOLl (Drosophila) family, [Score=50.4, Expect=6e-06]} {RNA1310_7084} {RNA815_47699}
8. MligTC455_16739 628 13.08 Mlig455_040111

Neo: -

Age: logFC(26M/2M)=-0.328

Region-enriched R2: 3.456/0.01732
Region-enriched R5: 2.743/0.00527

Regeneration-downregulated R5: -4.251

Regeneration-depleted R5: -4.251

PCSK1 2.503 - - - 0.958 0.791 0.754 Mlig455_040111 {REF} {Length: 2929} {Pfam: Subtilase family [PF00082.24, score=160.6]; Proprotein convertase P-domain [PF01483.22, score=87.0]; Peptidase S8 pro-domain [PF16470.7, score=50.0]} {Human: ENSG00000175426, PCSK1, proprotein convertase subtilisin/kexin type 1, [RH, Score=550, Expect=0.0]} {Mouse: ENSMUSG00000021587, Pcsk1, proprotein convertase subtilisin/kexin type 1, [RH, Score=550, Expect=0.0]} {Dmel: FBgn0004598, Fur2, Furin 2, [Score=483, Expect=1e-152]} {Celegans: WBGene00002232, kpc-1, Furin-like protease kpc-1, [Score=468, Expect=3e-156]} {Smed: dd_Smed_v6_8406_0_1, dd_Smed_v6_8406_0_1, [RH, Score=474, Expect=2e-159]} {RNA1509_20395} {RNA1310_6257} {RNA815_2270.1}
9. MligTC455_51238 58 1.21 Mlig455_011511

Neo: -

Age: -

KCNMA1 2.435 - - - 0.957 0.713 0.765 Mlig455_011511 {REF} {Length: 2300} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=100.8]; Ion channel [PF07885.18, score=29.2]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=272, Expect=4e-80]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=271, Expect=4e-79]} {Dmel: FBgn0003429, slo, slowpoke, [Score=180, Expect=8e-48]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=269, Expect=9e-79]} {Smed: dd_Smed_v6_5509_0_1, dd_Smed_v6_5509_0_1, [Score=294, Expect=9e-88]} {RNA1310_5274} {RNA815_44227}
10. MligTC455_17221 720 14.99 Mlig455_060863

Neo: -

Age: logFC(26M/2M)=-0.303

2.424 - 0.717 - 0.954 0.753 - Mlig455_060863 {REF} {Length: 1498} {RNA1509_54942, RNA1509_56041} {RNA1310_43309, RNA1509_54942, RNA1509_56041} {RNA1509_54942, RNA1509_56041, RNA815_43486}
11. MligTC455_52814 47 0.97 Mlig455_047356, Mlig455_047365

Neo: -

Age: -

CNTN2 2.385 - - 0.718 0.957 - 0.710

Mlig455_047356 {REF} {Length: 2537} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=57.8]; Immunoglobulin domain [PF13927.8, score=52.6]; Immunoglobulin domain [PF13895.8, score=40.4]; Immunoglobulin domain [PF00047.27, score=40.3]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=25.9]} {Human: ENSG00000184144, CNTN2, contactin 2, [Score=58.5, Expect=3e-08]} {Mouse: ENSMUSG00000053024, Cntn2, contactin 2, [Score=56.6, Expect=8e-08]; ENSMUSG00000061751, Kalrn, kalirin, RhoGEF kinase, [Score=55.1, Expect=2e-07]; ENSMUSG00000020674, Pxdn, peroxidasin, [Score=54.7, Expect=3e-07]} {Dmel: FBgn0264975, Nrg, Neuroglian, [Score=58.2, Expect=2e-08]} {Smed: dd_Smed_v6_15129_0_1, dd_Smed_v6_15129_0_1, [RH, Score=99.8, Expect=2e-22]} {RNA1509_60115} {RNA1310_31768} {RNA815_18728}

Mlig455_047365 {REF} {Length: 3489} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=57.9]; Immunoglobulin domain [PF13927.8, score=52.8]; Immunoglobulin domain [PF13895.8, score=40.5]; Immunoglobulin domain [PF00047.27, score=40.3]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=26.4]} {Human: ENSG00000184144, CNTN2, contactin 2, [Score=57.4, Expect=5e-08]} {Mouse: ENSMUSG00000053024, Cntn2, contactin 2, [Score=55.5, Expect=1e-07]; ENSMUSG00000020674, Pxdn, peroxidasin, [Score=53.9, Expect=5e-07]; ENSMUSG00000061751, Kalrn, kalirin, RhoGEF kinase, [Score=53.5, Expect=6e-07]; ENSMUSG00000055022, Cntn1, contactin 1, [Score=52.8, Expect=1e-06]; ENSMUSG00000030075, Cntn3, contactin 3, [Score=52.8, Expect=1e-06]} {Dmel: FBgn0264975, Nrg, Neuroglian, [Score=55.5, Expect=1e-07]} {Smed: dd_Smed_v6_15129_0_1, dd_Smed_v6_15129_0_1, [RH, Score=99.8, Expect=1e-22]} {RNA1509_60115} {RNA1310_31768} {RNA815_19521}
12. MligTC455_37786 1733 36.1 Mlig455_019324, Mlig455_019438, Mlig455_019545

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.251

1.844 - - - 0.891 - 0.953

Mlig455_019324 {REF} {Length: 3964} {Pfam: FAM216B protein family [PF15107.8, score=19.0]} {RNA1509_21362, RNA1509_30523} {RNA1310_10336.1, RNA1509_30523} {RNA1509_30523, RNA815_4271}

Mlig455_019438 {REF} {Length: 1903} {Pfam: FAM216B protein family [PF15107.8, score=19.0]} {RNA1509_21362} {RNA1310_10336.1, RNA1509_21362} {RNA1509_21362, RNA815_4271}

Mlig455_019545 {REF} {Length: 3361} {Pfam: FAM216B protein family [PF15107.8, score=18.9]} {RNA1509_21362} {RNA1310_10336.1} {RNA815_4271}
13. MligTC455_39747 9244 192.57 Mlig455_062337

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.251

1.82 - - - 0.982 0.838 - Mlig455_062337 {REF} {Length: 1172} {Celegans: WBGene00001446, flp-3, FMRFamide-like neuropeptides 3 SPLGTMRF-amide TPLGTMRF-amide SAEPFGTMRF-amide NPENDTPFGTMRF-amide ASEDALFGTMRF-amide EAEEPLGTMRF-amide SADDSAPFGTMRF-amide NPLGTMRF-amide, [Score=60.1, Expect=9e-11]} {Smed: dd_Smed_v6_1902_0_1, dd_Smed_v6_1902_0_1, [RH, Score=47.4, Expect=2e-07]} {RNA1509_16548, RNA1509_58675} {RNA1310_55834.1, RNA1509_58675} {RNA1509_58675, RNA815_29732}
14. MligTC455_51429 110 2.29 Mlig455_024820, Mlig455_024899

Neo: -

Age: Up-Down-Down

KCNK18 1.814 - 0.854 - 0.960 - -

Mlig455_024820 {REF} {Length: 2654} {Pfam: Ion channel [PF07885.18, score=117.7]; Ion transport protein [PF00520.33, score=25.7]} {Human: ENSG00000186795, KCNK18, potassium two pore domain channel subfamily K member 18, [RH, Score=102, Expect=6e-23]} {Mouse: ENSMUSG00000040901, Kcnk18, potassium channel, subfamily K, member 18, [Score=101, Expect=7e-23]; ENSMUSG00000033854, Kcnk10, potassium channel, subfamily K, member 10, [Score=97.8, Expect=3e-21]} {Dmel: FBgn0033257, sand, sandman, [RH, Score=159, Expect=1e-43]} {Celegans: WBGene00010784, twk-48, TWiK family of potassium channels, [Score=171, Expect=4e-48]} {Smed: dd_Smed_v6_19825_0_1, dd_Smed_v6_19825_0_1, [RH, Score=333, Expect=5e-110]} {RNA1509_56216} {RNA1310_14699.1, RNA1509_56216} {RNA1509_56216, RNA815_23055}

Mlig455_024899 {REF} {Length: 3465} {Pfam: Ion channel [PF07885.18, score=115.6]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=113.8]; Ion transport protein [PF00520.33, score=23.7]} {Human: ENSG00000186795, KCNK18, potassium two pore domain channel subfamily K member 18, [RH, Score=101, Expect=2e-22]} {Mouse: ENSMUSG00000040901, Kcnk18, potassium channel, subfamily K, member 18, [Score=101, Expect=2e-22]; ENSMUSG00000033854, Kcnk10, potassium channel, subfamily K, member 10, [Score=97.4, Expect=1e-20]} {Dmel: FBgn0033257, sand, sandman, [RH, Score=159, Expect=3e-42]} {Celegans: WBGene00010784, twk-48, TWiK family of potassium channels, [Score=170, Expect=2e-46]} {Smed: dd_Smed_v6_19825_0_1, dd_Smed_v6_19825_0_1, [RH, Score=333, Expect=3e-106]} {RNA1509_56216} {RNA1310_14699.1} {RNA815_252.1}
15. MligTC455_35409 2095 43.64 Mlig455_004509

Neo: -

Age: -

PPP3CA 1.793 0.988 0.805 - - - - Mlig455_004509 {REF} {Length: 4292} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=129.1]} {Human: ENSG00000138814, PPP3CA, protein phosphatase 3 catalytic subunit alpha, [RH, Score=837, Expect=0.0]; ENSG00000107758, PPP3CB, protein phosphatase 3 catalytic subunit beta, [RH, Score=823, Expect=0.0]; ENSG00000120910, PPP3CC, protein phosphatase 3 catalytic subunit gamma, [RH, Score=800, Expect=0.0]} {Mouse: ENSMUSG00000028161, Ppp3ca, protein phosphatase 3, catalytic subunit, alpha isoform, [RH, Score=840, Expect=0.0]; ENSMUSG00000021816, Ppp3cb, protein phosphatase 3, catalytic subunit, beta isoform, [RH, Score=823, Expect=0.0]} {Dmel: FBgn0011826, Pp2B-14D, Protein phosphatase 2B at 14D, [RH, Score=846, Expect=0.0]} {Celegans: WBGene00006527, tax-6, Serine/threonine-protein phosphatase 2B catalytic subunit, [RH, Score=771, Expect=0.0]} {Smed: dd_Smed_v6_2045_0_1, dd_Smed_v6_2045_0_1, [RH, Score=674, Expect=0.0]} {RNA1509_25279, RNA1509_42566, RNA1509_9529} {RNA1310_10900, RNA1509_25279, RNA1509_42566, RNA1509_9529} {RNA1509_25279, RNA1509_42566, RNA1509_9529, RNA815_6996}
16. MligTC455_45730 87 1.81 Mlig455_020296

Neo: -

Age: Down-Up-Up

Region-enriched R2: 8.589/0.00002

SSUH2 1.77 - - 0.817 0.953 - - Mlig455_020296 {REF} {Length: 1680} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=197, Expect=3e-59]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=155, Expect=9e-44]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=127, Expect=5e-33]} {RNA1310_19609.2} {RNA815_22113.1}
17. MligTC455_52003 1043 21.73 Mlig455_050564, Mlig455_050571

Neo: -

Age: -

RGS4, RGS8 1.766 0.798 - - 0.968 - -

Mlig455_050564 {REF} {Length: 3240} {Pfam: Regulator of G protein signaling domain [PF00615.21, score=116.7]} {Human: ENSG00000117152, RGS4, regulator of G protein signaling 4, [RH, Score=149, Expect=2e-42]} {Mouse: ENSMUSG00000038530, Rgs4, regulator of G-protein signaling 4, [RH, Score=153, Expect=4e-44]; ENSMUSG00000026678, Rgs5, regulator of G-protein signaling 5, [RH, Score=149, Expect=1e-42]; ENSMUSG00000042671, Rgs8, regulator of G-protein signaling 8, [RH, Score=149, Expect=1e-42]} {Dmel: FBgn0028743, Dhit, Double hit, [Score=118, Expect=2e-30]} {Celegans: WBGene00004350, rgs-7, Regulator of G-protein signaling rgs-7, [Score=124, Expect=4e-33]} {Smed: dd_Smed_v6_8648_0_1, dd_Smed_v6_8648_0_1, [RH, Score=199, Expect=4e-58]} {RNA1509_11015, RNA1509_27306} {RNA1310_4876, RNA1509_11015, RNA1509_27306} {RNA1509_11015, RNA1509_27306, RNA815_6054}

Mlig455_050571 {REF} {Length: 2222} {Pfam: Regulator of G protein signaling domain [PF00615.21, score=118.3]} {Human: ENSG00000135824, RGS8, regulator of G protein signaling 8, [RH, Score=149, Expect=9e-45]; ENSG00000117152, RGS4, regulator of G protein signaling 4, [RH, Score=149, Expect=2e-44]; ENSG00000150681, RGS18, regulator of G protein signaling 18, [RH, Score=146, Expect=5e-43]; ENSG00000143248, RGS5, regulator of G protein signaling 5, [RH, Score=144, Expect=7e-43]} {Mouse: ENSMUSG00000038530, Rgs4, regulator of G-protein signaling 4, [RH, Score=153, Expect=5e-46]; ENSMUSG00000042671, Rgs8, regulator of G-protein signaling 8, [RH, Score=151, Expect=1e-45]; ENSMUSG00000026678, Rgs5, regulator of G-protein signaling 5, [RH, Score=147, Expect=7e-44]} {Dmel: FBgn0028743, Dhit, Double hit, [Score=117, Expect=1e-31]} {Celegans: WBGene00004350, rgs-7, Regulator of G-protein signaling rgs-7, [Score=124, Expect=7e-35]} {Smed: dd_Smed_v6_8648_0_1, dd_Smed_v6_8648_0_1, [RH, Score=192, Expect=1e-57]} {RNA1509_27306} {RNA1310_5436.1} {RNA815_6054}
18. MligTC455_12131 23 0.47 Mlig455_013913

Neo: -

Age: -

1.755 - - - 0.950 0.805 - Mlig455_013913 {REF} {Length: 1451} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=38.4]} {Smed: dd_Smed_v6_33525_0_1, dd_Smed_v6_33525_0_1, [Score=115, Expect=4e-30]} {RNA1310_68929} {RNA815_54261}
19. MligTC455_52238 282 5.87 Mlig455_029211

Neo: -

Age: logFC(26M/2M)=-0.312

ABCG2 1.721 - - 0.768 0.953 - - Mlig455_029211 {REF} {Length: 3240} {Human: ENSG00000118777, ABCG2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=80.5, Expect=3e-15]} {Mouse: ENSMUSG00000029802, Abcg2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=79.0, Expect=7e-15]} {Smed: dd_Smed_v6_4225_0_1, dd_Smed_v6_4225_0_1, [Score=108, Expect=2e-24]} {RNA1509_38878} {RNA1310_949.2} {RNA815_1895}
20. MligTC455_36977 113 2.36 Mlig455_035675, Mlig455_035771, Mlig455_035772, Mlig455_035774, Mlig455_035880, Mlig455_035885

Neo: -

Age: Up-Down-Down

KIF1A 1.678 - - - 0.952 0.726 -

Mlig455_035675 {REF} {Length: 7705} {Pfam: Kinesin motor domain [PF00225.25, score=358.7]; Kinesin-associated [PF16183.7, score=185.4]; Kinesin protein [PF12473.10, score=123.2]; Microtubule binding [PF16796.7, score=74.3]; Kinesin protein 1B [PF12423.10, score=41.4]; PH domain [PF00169.31, score=40.0]; FHA domain [PF00498.28, score=30.6]; Inner membrane component of T3SS, cytoplasmic domain [PF16697.7, score=22.8]} {Human: ENSG00000130294, KIF1A, kinesin family member 1A, [RH, Score=1638, Expect=0.0]} {Mouse: ENSMUSG00000014602, Kif1a, kinesin family member 1A, [RH, Score=1635, Expect=0.0]} {Dmel: FBgn0267002, unc-104, uncoordinated-104, [RH, Score=1515, Expect=0.0]} {Celegans: WBGene00006831, unc-104, Kinesin-like protein unc-104, [RH, Score=1374, Expect=0.0]} {Smed: dd_Smed_v6_7108_0_2, dd_Smed_v6_7108_0_2, [RH, Score=1588, Expect=0.0]} {RNA1509_46150} {RNA1310_1231} {RNA815_1937.1}

Mlig455_035771 {REF} {Length: 3339} {Pfam: Kinesin protein [PF12473.10, score=123.6]; Kinesin protein 1B [PF12423.10, score=42.1]; PH domain [PF00169.31, score=39.6]} {Human: ENSG00000130294, KIF1A, kinesin family member 1A, [Score=660, Expect=0.0]; ENSG00000054523, KIF1B, kinesin family member 1B, [Score=627, Expect=0.0]} {Mouse: ENSMUSG00000014602, Kif1a, kinesin family member 1A, [Score=657, Expect=0.0]} {Dmel: FBgn0267002, unc-104, uncoordinated-104, [Score=506, Expect=1e-157]} {Celegans: WBGene00006831, unc-104, Kinesin-like protein unc-104, [Score=449, Expect=3e-137]} {Smed: dd_Smed_v6_7108_0_1, dd_Smed_v6_7108_0_1, [Score=660, Expect=0.0]} {RNA1509_58310} {RNA1310_857.1} {RNA815_3511}

Mlig455_035772 {REF} {Length: 603} {Pfam: Kinesin motor domain [PF00225.25, score=358.7]; Kinesin-associated [PF16183.7, score=185.4]; Kinesin protein [PF12473.10, score=123.2]; Microtubule binding [PF16796.7, score=74.3]; Kinesin protein 1B [PF12423.10, score=41.4]; PH domain [PF00169.31, score=40.0]; FHA domain [PF00498.28, score=30.6]; Inner membrane component of T3SS, cytoplasmic domain [PF16697.7, score=22.8]} {Human: ENSG00000130294, KIF1A, kinesin family member 1A, [RH, Score=1638, Expect=0.0]} {Mouse: ENSMUSG00000014602, Kif1a, kinesin family member 1A, [RH, Score=1635, Expect=0.0]} {Dmel: FBgn0267002, unc-104, uncoordinated-104, [RH, Score=1515, Expect=0.0]} {Celegans: WBGene00006831, unc-104, Kinesin-like protein unc-104, [RH, Score=1374, Expect=0.0]} {Smed: dd_Smed_v6_7108_0_2, dd_Smed_v6_7108_0_2, [RH, Score=1588, Expect=0.0]} {RNA1509_58310} {RNA1310_5764} {RNA815_1937.1}

Mlig455_035774 {REF} {Length: 1155} {Pfam: Kinesin motor domain [PF00225.25, score=209.6]; Microtubule binding [PF16796.7, score=78.8]} {Human: ENSG00000130294, KIF1A, kinesin family member 1A, [Score=356, Expect=5e-122]; ENSG00000054523, KIF1B, kinesin family member 1B, [Score=352, Expect=4e-113]; ENSG00000129250, KIF1C, kinesin family member 1C, [Score=340, Expect=4e-109]} {Mouse: ENSMUSG00000014602, Kif1a, kinesin family member 1A, [Score=352, Expect=2e-111]; ENSMUSG00000063077, Kif1b, kinesin family member 1B, [Score=349, Expect=3e-112]; ENSMUSG00000020821, Kif1c, kinesin family member 1C, [Score=342, Expect=8e-117]} {Dmel: FBgn0267002, unc-104, uncoordinated-104, [Score=340, Expect=2e-107]} {Celegans: WBGene00006831, unc-104, Kinesin-like protein unc-104, [Score=317, Expect=3e-99]} {Smed: dd_Smed_v6_7108_0_1, dd_Smed_v6_7108_0_1, [Score=324, Expect=1e-101]} {RNA1509_46150} {RNA1310_1231} {RNA815_1937.2}

Mlig455_035880 {REF} {Length: 3595} {Pfam: Kinesin protein [PF12473.10, score=91.6]; Kinesin protein 1B [PF12423.10, score=42.7]} {Human: ENSG00000130294, KIF1A, kinesin family member 1A, [Score=432, Expect=4e-133]} {Mouse: ENSMUSG00000014602, Kif1a, kinesin family member 1A, [Score=431, Expect=7e-133]} {Dmel: FBgn0267002, unc-104, uncoordinated-104, [Score=418, Expect=1e-128]} {Celegans: WBGene00006831, unc-104, Kinesin-like protein unc-104, [Score=372, Expect=2e-112]} {Smed: dd_Smed_v6_7108_0_2, dd_Smed_v6_7108_0_2, [Score=436, Expect=1e-134]} {RNA1509_58310} {RNA1310_857.2} {RNA815_3511}

Mlig455_035885 {REF} {Length: 1073} {Pfam: Kinesin motor domain [PF00225.25, score=209.6]; Microtubule binding [PF16796.7, score=78.8]} {Human: ENSG00000130294, KIF1A, kinesin family member 1A, [Score=356, Expect=5e-122]; ENSG00000054523, KIF1B, kinesin family member 1B, [Score=352, Expect=4e-113]; ENSG00000129250, KIF1C, kinesin family member 1C, [Score=340, Expect=4e-109]} {Mouse: ENSMUSG00000014602, Kif1a, kinesin family member 1A, [Score=352, Expect=2e-111]; ENSMUSG00000063077, Kif1b, kinesin family member 1B, [Score=349, Expect=3e-112]; ENSMUSG00000020821, Kif1c, kinesin family member 1C, [Score=342, Expect=8e-117]} {Dmel: FBgn0267002, unc-104, uncoordinated-104, [Score=340, Expect=2e-107]} {Celegans: WBGene00006831, unc-104, Kinesin-like protein unc-104, [Score=317, Expect=3e-99]} {Smed: dd_Smed_v6_7108_0_1, dd_Smed_v6_7108_0_1, [Score=324, Expect=1e-101]} {RNA1509_46150} {RNA1310_1231} {RNA815_1937.2}
21. MligTC455_46885 72 1.49 Mlig455_015138

Neo: -

Age: -

PRKG2 1.66 - - - 0.955 0.705 - Mlig455_015138 {REF} {Length: 3064} {Pfam: Protein kinase domain [PF00069.27, score=227.4]; Cyclic nucleotide-binding domain [PF00027.31, score=128.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=118.5]; Kinase-like [PF14531.8, score=25.1]} {Human: ENSG00000138669, PRKG2, protein kinase cGMP-dependent 2, [RH, Score=674, Expect=0.0]} {Mouse: ENSMUSG00000029334, Prkg2, protein kinase, cGMP-dependent, type II, [RH, Score=674, Expect=0.0]} {Dmel: FBgn0000442, Pkg21D, Protein kinase, cGMP-dependent at 21D, [RH, Score=682, Expect=0.0]} {Celegans: WBGene00001173, egl-4, cGMP-dependent protein kinase egl-4, [Score=668, Expect=0.0]} {Smed: dd_Smed_v6_6967_0_1, dd_Smed_v6_6967_0_1, [RH, Score=676, Expect=0.0]} {RNA1509_26653} {RNA1310_15330.1} {RNA815_26005}
22. MligTC455_48128 18 0.37 Mlig455_052326

Neo: -

Age: -

1.652 - - - 0.951 0.701 - Mlig455_052326 {REF} {Length: 3582} {RNA1310_42908} {RNA815_22744}
23. MligTC455_37005 759 15.82 Mlig455_062895

Neo: -

Age: logFC(26M/2M)=-0.530

Region-enriched R2: 2.906/0.01531
Region-enriched R6: 2.551/0.00476

SLC5A12 0.98 - - - 0.980 - - Mlig455_062895 {REF} {Length: 3080} {Pfam: Sodium:solute symporter family [PF00474.19, score=141.8]} {Human: ENSG00000148942, SLC5A12, solute carrier family 5 member 12, [RH, Score=452, Expect=1e-151]; ENSG00000256870, SLC5A8, solute carrier family 5 member 8, [RH, Score=444, Expect=1e-148]; ENSG00000262217, SLC5A8, solute carrier family 5 member 8, [RH, Score=444, Expect=1e-148]} {Mouse: ENSMUSG00000041644, Slc5a12, solute carrier family 5 (sodium/glucose cotransporter), member 12, [RH, Score=458, Expect=4e-154]; ENSMUSG00000020062, Slc5a8, solute carrier family 5 (iodide transporter), member 8, [RH, Score=436, Expect=1e-145]} {Dmel: FBgn0034494, CG10444, [RH, Score=412, Expect=6e-137]} {Celegans: WBGene00014092, ZK822.5, [RH, Score=273, Expect=2e-83]} {Smed: dd_Smed_v6_14173_0_1, dd_Smed_v6_14173_0_1, [RH, Score=481, Expect=6e-164]} {RNA1509_28319, RNA1509_8499} {RNA1310_12282.1, RNA1509_28319, RNA1509_8499} {RNA1509_28319, RNA1509_8499, RNA815_4467}
24. MligTC455_45537 189 3.94 Mlig455_060669

Neo: -

Age: Up-Down-Up

NPR1 0.97 - - - 0.970 - - Mlig455_060669 {REF} {Length: 2668} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=200.8]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=56.3]; Protein kinase domain [PF00069.27, score=41.4]} {Human: ENSG00000169418, NPR1, natriuretic peptide receptor 1, [Score=382, Expect=4e-123]; ENSG00000159899, NPR2, natriuretic peptide receptor 2, [Score=375, Expect=9e-121]} {Mouse: ENSMUSG00000027931, Npr1, natriuretic peptide receptor 1, [Score=394, Expect=7e-128]; ENSMUSG00000028469, Npr2, natriuretic peptide receptor 2, [Score=377, Expect=9e-126]} {Dmel: FBgn0051183, CG31183, [Score=374, Expect=8e-118]} {Celegans: WBGene00020131, gcy-28, Receptor-type guanylate cyclase gcy-28, [Score=348, Expect=1e-109]} {Smed: dd_Smed_v6_14331_0_1, dd_Smed_v6_14331_0_1, [Score=429, Expect=4e-141]} {RNA1509_50551} {RNA1310_4016.1} {RNA815_2101.1}
25. MligTC455_43352 95 1.98 Mlig455_036042, Mlig455_036143, Mlig455_036169

Neo: -

Age: -

0.969 - - - 0.969 - -

Mlig455_036042 {REF} {Length: 601} {NoTransDecoderORF} {RNA1310_52240} {RNA815_32818}

Mlig455_036143 {REF} {Length: 706} {RNA1310_52240} {RNA815_32818}

Mlig455_036169 {REF} {Length: 944} {NoTransDecoderORF} {RNA1310_52240} {RNA815_32818}
26. MligTC455_52210 5661 117.93 Mlig455_005609, Mlig455_014449, Mlig455_070190

Neo: -

Age: -

0.964 - - - 0.964 - -

Mlig455_005609 {REF} {Length: 747} {Pfam: Domain of unknown function (DUF4573) [PF15140.8, score=23.9]} {RNA1509_54058} {RNA1310_50049} {RNA815_23688.1}

Mlig455_014449 {REF} {Length: 881} {Pfam: Domain of unknown function (DUF4573) [PF15140.8, score=22.6]} {RNA1509_54058} {RNA1310_50296} {RNA815_23688.1}

Mlig455_070190 {REF} {Length: 692} {Pfam: Domain of unknown function (DUF4573) [PF15140.8, score=20.8]} {RNA1509_54058} {RNA1310_50296} {RNA815_23688.2}
27. MligTC455_44170 360 7.5 Mlig455_025145

Neo: -

Age: logFC(26M/2M)=-0.567

ATP10D 0.963 - - - - - 0.963 Mlig455_025145 {REF} {Length: 6187} {TRANSSPLICED} {Pfam: Phospholipid-translocating ATPase N-terminal [PF16209.7, score=77.9]; E1-E2 ATPase [PF00122.22, score=31.1]} {Human: ENSG00000145246, ATP10D, ATPase phospholipid transporting 10D (putative), [Score=414, Expect=8e-130]; ENSG00000206190, ATP10A, ATPase phospholipid transporting 10A (putative), [Score=413, Expect=2e-137]; ENSG00000118322, ATP10B, ATPase phospholipid transporting 10B (putative), [Score=399, Expect=3e-124]} {Mouse: ENSMUSG00000046808, Atp10d, ATPase, class V, type 10D, [Score=414, Expect=2e-129]; ENSMUSG00000025324, Atp10a, ATPase, class V, type 10A, [Score=410, Expect=6e-128]} {Dmel: FBgn0032120, CG33298, [Score=394, Expect=2e-122]} {Celegans: WBGene00012360, tat-3, Phospholipid-transporting ATPase, [Score=416, Expect=5e-131]} {Smed: dd_Smed_v6_5042_0_1, dd_Smed_v6_5042_0_1, [Score=430, Expect=7e-136]} {RNA1509_3928} {RNA1310_991} {RNA815_151.1}
28. MligTC455_44171 367 7.64 Mlig455_063907

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.658

ATP10A 0.961 - - - - - 0.961 Mlig455_063907 {REF} {Length: 5440} {TRANSSPLICED} {Pfam: Phospholipid-translocating P-type ATPase C-terminal [PF16212.7, score=210.9]; Phospholipid-translocating ATPase N-terminal [PF16209.7, score=76.7]; haloacid dehalogenase-like hydrolase [PF00702.28, score=55.6]; Cation transport ATPase (P-type) [PF13246.8, score=45.4]; E1-E2 ATPase [PF00122.22, score=29.4]} {Human: ENSG00000206190, ATP10A, ATPase phospholipid transporting 10A (putative), [RH, Score=905, Expect=0.0]; ENSG00000118322, ATP10B, ATPase phospholipid transporting 10B (putative), [RH, Score=899, Expect=0.0]; ENSG00000145246, ATP10D, ATPase phospholipid transporting 10D (putative), [RH, Score=880, Expect=0.0]} {Mouse: ENSMUSG00000025324, Atp10a, ATPase, class V, type 10A, [RH, Score=907, Expect=0.0]; ENSMUSG00000055415, Atp10b, ATPase, class V, type 10B, [RH, Score=888, Expect=0.0]} {Dmel: FBgn0032120, CG33298, [Score=483, Expect=9e-146]} {Celegans: WBGene00012360, tat-3, Phospholipid-transporting ATPase, [Score=454, Expect=5e-136]} {Smed: dd_Smed_v6_13628_0_1, dd_Smed_v6_13628_0_1, [Score=831, Expect=0.0]} {RNA1509_3928} {RNA1310_991, RNA1509_3928} {RNA1509_3928, RNA815_151.1}
29. MligTC455_21861 166 3.46 Mlig455_001636

Neo: -

Age: -

FAM234B 0.958 - - - 0.958 - - Mlig455_001636 {REF} {Length: 2805} {Pfam: FG-GAP-like repeat [PF13517.8, score=32.1]; PQQ-like domain [PF13360.8, score=26.1]; PQQ enzyme repeat [PF01011.23, score=25.0]} {Human: ENSG00000084444, FAM234B, family with sequence similarity 234 member B, [RH, Score=60.8, Expect=7e-09]} {Mouse: ENSMUSG00000030207, Fam234b, family with sequence similarity 234, member B, [RH, Score=62.8, Expect=1e-09]} {Dmel: FBgn0038725, CG6184, [Score=192, Expect=2e-50]} {Smed: dd_Smed_v6_12614_0_1, dd_Smed_v6_12614_0_1, [Score=239, Expect=5e-67]} {RNA1509_34189} {RNA1310_7071, RNA1509_34189} {RNA1509_34189, RNA815_18304}
30. MligTC455_16480 207 4.31 Mlig455_062142

Neo: -

Age: -

SLC16A14 0.955 - - - 0.955 - - Mlig455_062142 {REF} {Length: 2691} {Pfam: Major Facilitator Superfamily [PF07690.18, score=108.5]} {Human: ENSG00000163053, SLC16A14, solute carrier family 16 member 14, [Score=139, Expect=1e-34]; ENSG00000152779, SLC16A12, solute carrier family 16 member 12, [Score=138, Expect=3e-34]} {Mouse: ENSMUSG00000026220, Slc16a14, solute carrier family 16 (monocarboxylic acid transporters), member 14, [Score=137, Expect=8e-34]; ENSMUSG00000009378, Slc16a12, solute carrier family 16 (monocarboxylic acid transporters), member 12, [Score=135, Expect=2e-33]} {Dmel: FBgn0023549, Mct1, Monocarboxylate transporter 1, [Score=280, Expect=6e-85]} {Celegans: WBGene00003986, mct-4, MonoCarboxylate Transporter family, [Score=288, Expect=2e-87]} {Smed: dd_Smed_v6_9402_0_1, dd_Smed_v6_9402_0_1, [Score=236, Expect=3e-69]} {RNA1509_2727, RNA1509_46771} {RNA1310_12162, RNA1509_2727, RNA1509_46771} {RNA1509_2727, RNA1509_46771, RNA815_9650}
31. MligTC455_17002 37 0.76 Mlig455_011001

Neo: -

Age: logFC(26M/2M)=-1.400

P2RX2 0.955 - - - 0.955 - - Mlig455_011001 {REF} {Length: 3286} {Pfam: ATP P2X receptor [PF00864.21, score=289.2]} {Human: ENSG00000187848, P2RX2, purinergic receptor P2X 2, [Score=207, Expect=3e-60]; ENSG00000135124, P2RX4, purinergic receptor P2X 4, [Score=201, Expect=5e-59]} {Mouse: ENSMUSG00000029503, P2rx2, purinergic receptor P2X, ligand-gated ion channel, 2, [Score=202, Expect=9e-59]; ENSMUSG00000022758, P2rx6, purinergic receptor P2X, ligand-gated ion channel, 6, [Score=192, Expect=8e-56]} {Smed: dd_Smed_v6_10968_0_1, dd_Smed_v6_10968_0_1, [Score=270, Expect=2e-84]} {RNA1509_50956} {RNA1310_31414} {RNA815_43099}

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