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Results for MligTC455_39747

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_39747 9244 192.57 Mlig455_062337

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.251

Mlig455_062337 {REF} {Length: 1172} {Celegans: WBGene00001446, flp-3, FMRFamide-like neuropeptides 3 SPLGTMRF-amide TPLGTMRF-amide SAEPFGTMRF-amide NPENDTPFGTMRF-amide ASEDALFGTMRF-amide EAEEPLGTMRF-amide SADDSAPFGTMRF-amide NPLGTMRF-amide, [Score=60.1, Expect=9e-11]} {Smed: dd_Smed_v6_1902_0_1, dd_Smed_v6_1902_0_1, [RH, Score=47.4, Expect=2e-07]} {RNA1509_16548, RNA1509_58675} {RNA1310_55834.1, RNA1509_58675} {RNA1509_58675, RNA815_29732}

Cumulative graph for MligTC455_39747

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.493 7.598 0.49614 1.00000
RegionR2 1.029 7.598 0.10483 0.39903
RegionR3 -0.713 7.598 0.25269 0.79685
RegionR4 -0.149 7.598 0.81555 1.00000
RegionR5 -1.138 7.598 0.07153 0.24192
RegionR6 0.28 7.598 0.63105 1.00000
RegionR7 1.038 7.598 0.06448 0.48778
RegionR8 -0.841 7.598 0.22030 0.82817

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.738 7.598 0.40884 1.00000
RegenerationR2 -0.132 7.598 0.85853 1.00000
RegenerationR3 -0.061 7.598 0.93469 1.00000
RegenerationR4 -0.221 7.598 0.77102 0.97686
RegenerationR5 -0.079 7.598 0.91749 1.00000
RegenerationR6 -0.804 7.598 0.28877 0.63885
RegenerationBL -1.502 7.598 0.03254 0.20236
RegenerationTP -0.677 7.598 0.35814 0.79881


Genes with expression patterns similar to MligTC455_39747

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_39747 9244 192.57 Mlig455_062337

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.251

6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_062337 {REF} {Length: 1172} {Celegans: WBGene00001446, flp-3, FMRFamide-like neuropeptides 3 SPLGTMRF-amide TPLGTMRF-amide SAEPFGTMRF-amide NPENDTPFGTMRF-amide ASEDALFGTMRF-amide EAEEPLGTMRF-amide SADDSAPFGTMRF-amide NPLGTMRF-amide, [Score=60.1, Expect=9e-11]} {Smed: dd_Smed_v6_1902_0_1, dd_Smed_v6_1902_0_1, [RH, Score=47.4, Expect=2e-07]} {RNA1509_16548, RNA1509_58675} {RNA1310_55834.1, RNA1509_58675} {RNA1509_58675, RNA815_29732}
2. MligTC455_39748 17060 355.41 Mlig455_068905

Neo: -

Age: -

Region-enriched R7: 2.255/0.00030

Regeneration-downregulated BL: -3.088

Regeneration-depleted BL: -3.088

5.626 0.968 0.978 0.890 0.909 0.993 0.888 Mlig455_068905 {REF} {Length: 1123} {Celegans: WBGene00001446, flp-3, FMRFamide-like neuropeptides 3 SPLGTMRF-amide TPLGTMRF-amide SAEPFGTMRF-amide NPENDTPFGTMRF-amide ASEDALFGTMRF-amide EAEEPLGTMRF-amide SADDSAPFGTMRF-amide NPLGTMRF-amide, [Score=52.4, Expect=4e-08]} {Smed: dd_Smed_v6_1902_0_1, dd_Smed_v6_1902_0_1, [RH, Score=47.4, Expect=2e-07]} {RNA1509_13775, RNA1509_15073, RNA1509_16548, RNA1509_23529, RNA1509_549} {RNA1310_55834.1, RNA1509_13775, RNA1509_15073, RNA1509_16548, RNA1509_23529, RNA1509_549} {RNA1509_13775, RNA1509_15073, RNA1509_16548, RNA1509_23529, RNA1509_549, RNA815_29732}
3. MligTC455_53579 15576 324.49 Mlig455_010515

Neo: -

Age: -

Region-enriched R2: 1.446/0.00265

Regeneration-downregulated BL: -1.566

Regeneration-depleted BL: -1.566

4.295 0.742 - 0.854 0.815 0.979 0.905 Mlig455_010515 {REF} {Length: 1448} {Pfam: Neuroendocrine protein 7B2 precursor (Secretogranin V) [PF05281.13, score=80.3]} {Dmel: FBgn0041707, 7B2, [RH, Score=70.1, Expect=2e-13]} {Celegans: WBGene00011392, sbt-1, Seven B Two (Mammalian 7BT prohormone convertase chaperone) homolog, [RH, Score=67.4, Expect=5e-13]} {Smed: dd_Smed_v6_3862_0_1, dd_Smed_v6_3862_0_1, [RH, Score=119, Expect=7e-32]} {RNA1509_1202, RNA1509_1348, RNA1509_17830} {RNA1310_24594, RNA1509_1202, RNA1509_1348, RNA1509_17830} {RNA1509_1202, RNA1509_1348, RNA1509_17830, RNA815_8289}
4. MligTC455_53580 10830 225.63 Mlig455_061858

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.371

Region-specific R2: 2.295

Region-enriched R2: 1.602/0.00040

Regeneration-downregulated BL: -1.692

Regeneration-depleted BL: -1.692

4.27 0.739 - 0.827 0.815 0.953 0.936 Mlig455_061858 {REF} {Length: 1839} {Pfam: Neuroendocrine protein 7B2 precursor (Secretogranin V) [PF05281.13, score=32.7]} {Smed: dd_Smed_v6_3862_0_1, dd_Smed_v6_3862_0_1, [Score=77.4, Expect=9e-17]} {RNA1509_2808} {RNA1310_24594} {RNA815_8289}
5. MligTC455_53581 10826 225.54 Mlig455_061865

Neo: -

Age: Down-Down-Up

Region-specific R2: 2.296

Region-enriched R2: 1.603/0.00040

Regeneration-downregulated BL: -1.690

Regeneration-depleted BL: -1.690

4.27 0.739 - 0.827 0.815 0.953 0.936 Mlig455_061865 {REF} {Length: 1605} {Pfam: Neuroendocrine protein 7B2 precursor (Secretogranin V) [PF05281.13, score=82.0]} {Dmel: FBgn0041707, 7B2, [RH, Score=70.1, Expect=1e-13]} {Celegans: WBGene00011392, sbt-1, Seven B Two (Mammalian 7BT prohormone convertase chaperone) homolog, [RH, Score=67.4, Expect=4e-13]} {Smed: dd_Smed_v6_3862_0_1, dd_Smed_v6_3862_0_1, [RH, Score=118, Expect=1e-31]} {RNA1509_1202, RNA1509_24767} {RNA1310_24594, RNA1509_24767} {RNA1509_24767, RNA815_8289}
6. MligTC455_14831 280 5.83 Mlig455_067864

Neo: -

Age: Up-Down-Up

Region-enriched R2: 3.261/0.00352

SSUH2 4.237 0.786 0.767 - 0.934 0.978 0.772 Mlig455_067864 {REF} {Length: 1575} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=184, Expect=6e-54]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=148, Expect=7e-41]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=118, Expect=1e-29]} {RNA1509_46058} {RNA1310_5028.1} {RNA815_5650}
7. MligTC455_44513 1822 37.96 Mlig455_044390

Neo: -

Age: Down-Up-Up

Region-specific R2: 2.967

Region-enriched R2: 2.054/0.00008

3.554 - - 0.918 0.845 0.956 0.835 Mlig455_044390 {REF} {Length: 727} {Smed: dd_Smed_v6_5576_0_1, dd_Smed_v6_5576_0_1, [Score=93.2, Expect=5e-25]} {RNA1509_30750, RNA1509_53240, RNA1509_6792} {RNA1310_36193, RNA1509_30750, RNA1509_53240, RNA1509_6792} {RNA1509_30750, RNA1509_53240, RNA1509_6792, RNA815_16957}
8. MligTC455_51764 938 19.55 Mlig455_016061

Neo: -

Age: -

Region-specific R2: 2.881

Region-enriched R2: 1.672/0.00180

3.539 0.930 - 0.774 0.872 0.963 - Mlig455_016061 {REF} {Length: 649} {RNA1509_58232} {RNA1310_60107.1, RNA1509_58232} {RNA1509_58232, RNA815_31573}
9. MligTC455_47807 2664 55.5 Mlig455_050143

Neo: -

Age: -

Region-specific R2: 3.807

Region-enriched R2: 2.561/0.00001

3.503 - - 0.811 0.816 0.985 0.891 Mlig455_050143 {REF} {Length: 1560} {RNA1509_1605, RNA1509_28756} {RNA1310_30659.1, RNA1509_28756} {RNA1509_28756, RNA815_13807}
10. MligTC455_47806 2724 56.76 Mlig455_033677

Neo: -

Age: -

Region-specific R2: 3.773

Region-enriched R2: 2.504/0.00005

3.412 - - 0.738 0.825 0.985 0.864 Mlig455_033677 {REF} {Length: 1836} {RNA1509_1605, RNA1509_16422, RNA1509_33244, RNA1509_46504} {RNA1310_30659.1, RNA1509_1605, RNA1509_16422, RNA1509_33244, RNA1509_46504} {RNA1509_1605, RNA1509_16422, RNA1509_33244, RNA1509_46504, RNA815_13807}
11. MligTC455_53414 331 6.9 Mlig455_053442

Neo: -

Age: -

Region-specific R2: 4.308

Region-enriched R2: 3.374/0.00040

RP1 3.404 0.760 - - 0.916 0.956 0.772 Mlig455_053442 {REF} {Length: 1156} {Pfam: PLAT/LH2 domain [PF01477.25, score=155.8]; Doublecortin [PF03607.19, score=103.5]; Embryo-specific protein 3, (ATS3) [PF06232.13, score=22.0]} {Human: ENSG00000104237, RP1, RP1, axonemal microtubule associated, [Score=473, Expect=5e-146]} {Mouse: ENSMUSG00000025900, Rp1, retinitis pigmentosa 1 (human), [Score=454, Expect=1e-136]} {Dmel: FBgn0261387, CG17528, [Score=56.6, Expect=1e-07]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [Score=75.5, Expect=2e-13]} {Smed: dd_Smed_v6_10315_0_2, dd_Smed_v6_10315_0_2, [Score=698, Expect=0.0]} {RNA1509_21828} {RNA1310_33070.1} {RNA815_13802.1}
12. MligTC455_53415 319 6.64 Mlig455_053444

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.862

Region-enriched R2: 4.179/0.00011

RP1 3.398 0.760 - - 0.911 0.954 0.773 Mlig455_053444 {REF} {Length: 4944} {Pfam: PLAT/LH2 domain [PF01477.25, score=155.3]; Doublecortin [PF03607.19, score=100.5]; Embryo-specific protein 3, (ATS3) [PF06232.13, score=22.5]; Fibroblast growth factor [PF00167.20, score=18.6]} {Human: ENSG00000104237, RP1, RP1, axonemal microtubule associated, [Score=471, Expect=6e-145]} {Mouse: ENSMUSG00000025900, Rp1, retinitis pigmentosa 1 (human), [Score=453, Expect=3e-136]} {Dmel: FBgn0261387, CG17528, [Score=56.6, Expect=1e-07]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [Score=75.9, Expect=1e-13]} {Smed: dd_Smed_v6_10315_0_2, dd_Smed_v6_10315_0_2, [Score=691, Expect=0.0]} {RNA1509_59703} {RNA1310_2710} {RNA815_17469}
13. MligTC455_54204 344 7.17 Mlig455_006398

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.351

Region-specific R2: 5.395

Region-enriched R2: 4.187/0.01201

MYH6 3.351 - - 0.820 0.774 0.987 0.770 Mlig455_006398 {REF} {Length: 7465} {Pfam: Myosin head (motor domain) [PF00063.23, score=927.6]; Myosin tail [PF01576.21, score=593.3]; Myosin N-terminal SH3-like domain [PF02736.21, score=60.7]; Crescentin protein [PF19220.2, score=26.4]; Macoilin family [PF09726.11, score=19.0]} {Human: ENSG00000197616, MYH6, myosin heavy chain 6, [RH, Score=2074, Expect=0.0]; ENSG00000092054, MYH7, myosin heavy chain 7, [RH, Score=2064, Expect=0.0]; ENSG00000125414, MYH2, myosin heavy chain 2, [RH, Score=2019, Expect=0.0]; ENSG00000109061, MYH1, myosin heavy chain 1, [RH, Score=2012, Expect=0.0]; ENSG00000133020, MYH8, myosin heavy chain 8, [RH, Score=2006, Expect=0.0]; ENSG00000264424, MYH4, myosin heavy chain 4, [RH, Score=1991, Expect=0.0]; ENSG00000109063, MYH3, myosin heavy chain 3, [RH, Score=1973, Expect=0.0]} {Mouse: ENSMUSG00000040752, Myh6, myosin, heavy polypeptide 6, cardiac muscle, alpha, [RH, Score=2073, Expect=0.0]; ENSMUSG00000053093, Myh7, myosin, heavy polypeptide 7, cardiac muscle, beta, [RH, Score=2063, Expect=0.0]; ENSMUSG00000057003, Myh4, myosin, heavy polypeptide 4, skeletal muscle, [RH, Score=2039, Expect=0.0]; ENSMUSG00000056328, Myh1, myosin, heavy polypeptide 1, skeletal muscle, adult, [RH, Score=2016, Expect=0.0]; ENSMUSG00000055775, Myh8, myosin, heavy polypeptide 8, skeletal muscle, perinatal, [RH, Score=2014, Expect=0.0]; ENSMUSG00000033196, Myh2, myosin, heavy polypeptide 2, skeletal muscle, adult, [RH, Score=2008, Expect=0.0]; ENSMUSG00000020908, Myh3, myosin, heavy polypeptide 3, skeletal muscle, embryonic, [RH, Score=1981, Expect=0.0]; ENSMUSG00000060180, Myh13, myosin, heavy polypeptide 13, skeletal muscle, [RH, Score=1978, Expect=0.0]} {Dmel: FBgn0264695, Mhc, Myosin heavy chain, [RH, Score=2100, Expect=0.0]} {Celegans: WBGene00019064, myo-5, MYOsin heavy chain structural genes, [RH, Score=1993, Expect=0.0]} {Smed: dd_Smed_v6_579_0_1, dd_Smed_v6_579_0_1, [RH, Score=2702, Expect=0.0]} {RNA1509_16048, RNA1509_42411} {RNA1310_1388, RNA1509_42411} {RNA1509_42411, RNA815_129.1}
14. MligTC455_35294 1547 32.23 Mlig455_001167, Mlig455_001326, Mlig455_070580

Neo: -

Age: Down-Up-Up

Region-enriched R8: 1.741/0.00233
Region-enriched R2: 1.304/0.02383

GRIA2, GRID1 3.346 0.771 - 0.773 - 0.956 0.846

Mlig455_001167 {REF} {Length: 3625} {Pfam: Ligand-gated ion channel [PF00060.28, score=89.8]; Universal stress protein family [PF00582.28, score=80.5]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=33.4]; Receptor family ligand binding region [PF01094.30, score=23.9]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=19.3]} {Human: ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=123, Expect=6e-28]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=120, Expect=3e-27]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=117, Expect=5e-26]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=123, Expect=3e-28]; ENSMUSG00000041078, Grid1, glutamate receptor, ionotropic, delta 1, [Score=117, Expect=4e-26]} {Dmel: FBgn0038837, CG3822, [Score=124, Expect=9e-29]} {Celegans: WBGene00001615, glr-4, GLutamate Receptor family (AMPA), [Score=113, Expect=2e-25]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=220, Expect=2e-63]} {RNA1509_17988} {RNA1310_23557} {RNA815_11623.1}

Mlig455_001326 {REF} {Length: 3494} {Pfam: Ligand-gated ion channel [PF00060.28, score=92.1]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=33.4]; Receptor family ligand binding region [PF01094.30, score=23.1]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=19.8]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=121, Expect=2e-27]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=118, Expect=2e-26]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=124, Expect=2e-28]} {Dmel: FBgn0038840, Grik, [Score=125, Expect=7e-29]} {Celegans: WBGene00001615, glr-4, GLutamate Receptor family (AMPA), [Score=114, Expect=1e-25]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=220, Expect=9e-64]} {RNA1509_17988} {RNA1310_23557} {RNA815_11623.1}

Mlig455_070580 {REF} {Length: 3686} {Pfam: Ligand-gated ion channel [PF00060.28, score=92.1]; Universal stress protein family [PF00582.28, score=80.3]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=33.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=33.2]; Receptor family ligand binding region [PF01094.30, score=22.8]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=125, Expect=1e-28]; ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=122, Expect=1e-27]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=128, Expect=1e-29]} {Dmel: FBgn0038837, CG3822, [Score=135, Expect=4e-32]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=119, Expect=4e-27]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=237, Expect=2e-69]} {RNA1509_17988} {RNA1310_23557} {RNA815_11623.1}
15. MligTC455_48603 1006 20.95 Mlig455_058556

Neo: -

Age: -

Region-enriched R2: 1.380/0.01205

Regeneration-downregulated BL: -2.368

Regeneration-depleted BL: -2.368

CALM2 3.338 - 0.729 0.782 0.871 0.956 - Mlig455_058556 {REF} {Length: 2727} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=101.0]; EF hand [PF00036.34, score=97.2]; EF-hand domain pair [PF13833.8, score=81.7]; EF-hand domain [PF13405.8, score=78.5]; EF hand [PF13202.8, score=71.6]; EF-hand domain [PF14658.8, score=41.8]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=31.1]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=27.3]; Dockerin type I domain [PF00404.20, score=25.5]; SurA N-terminal domain [PF13624.8, score=19.1]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=132, Expect=1e-37]; ENSG00000160014, CALM3, calmodulin 3, [Score=130, Expect=5e-37]; ENSG00000198668, CALM1, calmodulin 1, [Score=130, Expect=3e-37]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=135, Expect=8e-39]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=130, Expect=3e-37]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=130, Expect=3e-37]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=127, Expect=3e-36]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=127, Expect=2e-36]} {Smed: dd_Smed_v6_12048_0_2, dd_Smed_v6_12048_0_2, [RH, Score=163, Expect=8e-49]} {RNA1509_36324, RNA1509_52694, RNA1509_5720} {RNA1310_6210.2, RNA1509_36324, RNA1509_52694, RNA1509_5720} {RNA1509_36324, RNA1509_52694, RNA1509_5720, RNA815_4293.1}
16. MligTC455_30487 7077 147.44 Mlig455_046773, Mlig455_060559

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.573

3.26 0.723 - - 0.840 0.957 0.740

Mlig455_046773 {REF} {Length: 1094} {RNA1509_13428, RNA1509_37924, RNA1509_44808} {RNA1310_38257.2, RNA1509_13428, RNA1509_44808} {RNA1509_13428, RNA1509_44808, RNA815_6548}

Mlig455_060559 {REF} {Length: 1175} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=24.0]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=21.4]} {Celegans: WBGene00008885, F16C3.1, [Score=53.9, Expect=8e-08]} {Smed: dd_Smed_v6_26560_0_2, dd_Smed_v6_26560_0_2, [Score=97.4, Expect=2e-22]}
17. MligTC455_54203 182 3.79 Mlig455_061249

Neo: -

Age: -

MYH7 3.241 - - 0.792 0.730 0.973 0.746 Mlig455_061249 {REF} {Length: 1536} {Pfam: Myosin tail [PF01576.21, score=90.6]} {Human: ENSG00000092054, MYH7, myosin heavy chain 7, [Score=200, Expect=8e-57]; ENSG00000197616, MYH6, myosin heavy chain 6, [Score=198, Expect=4e-56]; ENSG00000264424, MYH4, myosin heavy chain 4, [Score=191, Expect=2e-53]; ENSG00000125414, MYH2, myosin heavy chain 2, [Score=190, Expect=4e-53]} {Mouse: ENSMUSG00000053093, Myh7, myosin, heavy polypeptide 7, cardiac muscle, beta, [Score=201, Expect=4e-57]; ENSMUSG00000040752, Myh6, myosin, heavy polypeptide 6, cardiac muscle, alpha, [Score=194, Expect=8e-55]; ENSMUSG00000057003, Myh4, myosin, heavy polypeptide 4, skeletal muscle, [Score=192, Expect=3e-54]; ENSMUSG00000056328, Myh1, myosin, heavy polypeptide 1, skeletal muscle, adult, [Score=191, Expect=1e-53]} {Dmel: FBgn0264695, Mhc, Myosin heavy chain, [Score=282, Expect=2e-85]} {Celegans: WBGene00003515, myo-3, Myosin-3, [Score=241, Expect=2e-71]} {Smed: dd_Smed_v6_432_0_1, dd_Smed_v6_432_0_1, [Score=285, Expect=9e-87]} {RNA1509_55838} {RNA1310_1388} {RNA815_21073}
18. MligTC455_50464 64 1.34 Mlig455_007906, Mlig455_008010

Neo: -

Age: -

3.182 - 0.720 - 0.970 0.706 0.786

Mlig455_007906 {REF} {Length: 3294} {RNA1509_46103} {RNA1310_23886.1} {RNA815_8813.1}

Mlig455_008010 {REF} {Length: 1139} {RNA1509_46103} {RNA1310_23886.1} {RNA815_8813.1}
19. MligTC455_45730 87 1.81 Mlig455_020296

Neo: -

Age: Down-Up-Up

Region-enriched R2: 8.589/0.00002

SSUH2 2.698 - 0.849 - 0.978 0.871 - Mlig455_020296 {REF} {Length: 1680} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=197, Expect=3e-59]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=155, Expect=9e-44]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=127, Expect=5e-33]} {RNA1310_19609.2} {RNA815_22113.1}
20. MligTC455_18564 196 4.08 Mlig455_063527

Neo: -

Age: -

Region-enriched R2: 2.416/0.01839

PRKG2 2.689 - - - 0.958 0.944 0.787 Mlig455_063527 {REF} {Length: 2971} {Pfam: Protein kinase domain [PF00069.27, score=212.4]; Cyclic nucleotide-binding domain [PF00027.31, score=135.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=103.7]; Kinase-like [PF14531.8, score=24.8]} {Human: ENSG00000138669, PRKG2, protein kinase cGMP-dependent 2, [RH, Score=653, Expect=0.0]} {Mouse: ENSMUSG00000029334, Prkg2, protein kinase, cGMP-dependent, type II, [RH, Score=651, Expect=0.0]} {Dmel: FBgn0000442, Pkg21D, Protein kinase, cGMP-dependent at 21D, [RH, Score=662, Expect=0.0]} {Celegans: WBGene00001173, egl-4, cGMP-dependent protein kinase egl-4, [Score=655, Expect=0.0]} {Smed: dd_Smed_v6_6967_0_1, dd_Smed_v6_6967_0_1, [RH, Score=645, Expect=0.0]} {RNA1509_38353} {RNA1310_8466, RNA1509_38353} {RNA1509_38353, RNA815_6313}
21. MligTC455_53504 217 4.51 Mlig455_037385

Neo: -

Age: -

Region-enriched R2: 3.142/0.00738

CSMD1 2.679 - - - 0.957 0.964 0.758 Mlig455_037385 {REF} {Length: 2214} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=198.7]} {Human: ENSG00000183117, CSMD1, CUB and Sushi multiple domains 1, [Score=149, Expect=8e-37]} {Mouse: ENSMUSG00000028369, Svep1, sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1, [Score=136, Expect=7e-33]; ENSMUSG00000060924, Csmd1, CUB and Sushi multiple domains 1, [Score=134, Expect=5e-32]; ENSMUSG00000022311, Csmd3, CUB and Sushi multiple domains 3, [Score=133, Expect=9e-32]} {Dmel: FBgn0032797, Hasp, Hig-anchoring scaffold protein, [RH, Score=218, Expect=3e-60]} {Celegans: WBGene00002976, lev-9, [RH, Score=244, Expect=4e-72]} {Smed: dd_Smed_v6_13071_0_1, dd_Smed_v6_13071_0_1, [RH, Score=296, Expect=1e-91]} {RNA1509_55985} {RNA1310_12867.1, RNA1509_55985} {RNA1509_55985, RNA815_9157}
22. MligTC455_44120 125 2.61 Mlig455_041513

Neo: -

Age: Up-Down-Down

Region-enriched R2: 7.169/0.00020

2.673 - - - 0.967 0.914 0.792 Mlig455_041513 {REF} {Length: 644} {NoTransDecoderORF} {RNA1310_39164} {RNA815_4344}
23. MligTC455_20574 3347 69.74 Mlig455_021418

Neo: -

Age: -

PCSK2 2.669 - - - 0.899 0.981 0.789 Mlig455_021418 {REF} {Length: 1212} {Pfam: Peptidase S8 pro-domain [PF16470.7, score=47.7]} {Human: ENSG00000125851, PCSK2, proprotein convertase subtilisin/kexin type 2, [Score=53.9, Expect=2e-08]} {Mouse: ENSMUSG00000027419, Pcsk2, proprotein convertase subtilisin/kexin type 2, [Score=52.8, Expect=4e-08]} {Dmel: FBgn0023179, amon, amontillado, [Score=55.8, Expect=2e-09]} {Celegans: WBGene00001172, egl-3, Neuroendocrine convertase 2, [Score=61.2, Expect=3e-11]} {Smed: dd_Smed_v6_1566_0_1, dd_Smed_v6_1566_0_1, [Score=65.1, Expect=1e-12]} {RNA1509_15978} {RNA1310_7333.1} {RNA815_2403.2}
24. MligTC455_05889 28 0.58 Mlig455_027604, Mlig455_047689, Mlig455_047690

Neo: -

Age: -

TLR4 2.65 - - - 0.964 0.901 0.785

Mlig455_027604 {REF} {Length: 3445} {Pfam: Leucine rich repeat [PF13855.8, score=68.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=38.2]; TIR domain [PF01582.22, score=31.9]; TIR domain [PF13676.8, score=24.5]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=21.4]} {Human: ENSG00000136869, TLR4, toll like receptor 4, [RH, Score=74.3, Expect=6e-13]} {Mouse: ENSMUSG00000031558, Slit2, slit guidance ligand 2, [Score=60.1, Expect=1e-08]; ENSMUSG00000030600, Lrfn1, leucine rich repeat and fibronectin type III domain containing 1, [Score=59.3, Expect=2e-08]; ENSMUSG00000056427, Slit3, slit guidance ligand 3, [Score=58.5, Expect=4e-08]} {Dmel: FBgn0036494, Toll-6, [Score=80.5, Expect=4e-15]} {Celegans: WBGene00006593, tol-1, TOLl (Drosophila) family, [Score=50.4, Expect=6e-06]} {RNA1310_7084} {RNA815_22808}

Mlig455_047689 {REF} {Length: 352} {Pfam: Leucine rich repeat [PF13855.8, score=35.5]; Leucine Rich repeats (2 copies) [PF12799.9, score=20.6]} {RNA1310_7084} {RNA815_47088}

Mlig455_047690 {REF} {Length: 346} {Pfam: Leucine rich repeat [PF13855.8, score=68.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=38.2]; TIR domain [PF01582.22, score=31.9]; TIR domain [PF13676.8, score=24.5]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=21.4]} {Human: ENSG00000136869, TLR4, toll like receptor 4, [RH, Score=74.3, Expect=6e-13]} {Mouse: ENSMUSG00000031558, Slit2, slit guidance ligand 2, [Score=60.1, Expect=1e-08]; ENSMUSG00000030600, Lrfn1, leucine rich repeat and fibronectin type III domain containing 1, [Score=59.3, Expect=2e-08]; ENSMUSG00000056427, Slit3, slit guidance ligand 3, [Score=58.5, Expect=4e-08]} {Dmel: FBgn0036494, Toll-6, [Score=80.5, Expect=4e-15]} {Celegans: WBGene00006593, tol-1, TOLl (Drosophila) family, [Score=50.4, Expect=6e-06]} {RNA1310_7084} {RNA815_47699}
25. MligTC455_14830 177 3.68 Mlig455_066372

Neo: -

Age: -

SSUH2 2.612 - - - 0.956 0.907 0.749 Mlig455_066372 {REF} {Length: 1569} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=184, Expect=2e-53]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=148, Expect=1e-40]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=119, Expect=2e-29]} {RNA1509_46058} {RNA1310_5028.1, RNA1509_46058} {RNA1509_46058, RNA815_5650}
26. MligTC455_23150 3195 66.56 Mlig455_009524, Mlig455_009530

Neo: -

Age: -

Region-enriched R2: 3.504/0.00000
Region-enriched R3: 1.656/0.02560

CDK16 2.611 - - - 0.767 0.967 0.877

Mlig455_009524 {REF} {Length: 3287} {Pfam: Protein kinase domain [PF00069.27, score=218.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.2]} {Human: ENSG00000102225, CDK16, cyclin dependent kinase 16, [RH, Score=463, Expect=7e-159]; ENSG00000059758, CDK17, cyclin dependent kinase 17, [RH, Score=447, Expect=2e-151]} {Mouse: ENSMUSG00000031065, Cdk16, cyclin-dependent kinase 16, [RH, Score=464, Expect=2e-158]; ENSMUSG00000020015, Cdk17, cyclin-dependent kinase 17, [RH, Score=449, Expect=2e-152]} {Dmel: FBgn0005640, Eip63E, Ecdysone-induced protein 63E, [Score=362, Expect=2e-118]} {Celegans: WBGene00003961, pct-1, Cyclin-dependent kinase 17, [RH, Score=417, Expect=3e-138]} {Smed: dd_Smed_v6_4172_0_4, dd_Smed_v6_4172_0_4, [RH, Score=449, Expect=6e-151]} {RNA1509_23462} {RNA1310_21506} {RNA815_9702}

Mlig455_009530 {REF} {Length: 3384} {Pfam: Protein kinase domain [PF00069.27, score=208.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.4]; Haspin like kinase domain [PF12330.10, score=17.8]} {Human: ENSG00000102225, CDK16, cyclin dependent kinase 16, [Score=432, Expect=5e-147]} {Mouse: ENSMUSG00000031065, Cdk16, cyclin-dependent kinase 16, [Score=431, Expect=4e-146]} {Dmel: FBgn0005640, Eip63E, Ecdysone-induced protein 63E, [Score=329, Expect=9e-107]} {Celegans: WBGene00003961, pct-1, Cyclin-dependent kinase 17, [Score=392, Expect=2e-130]} {Smed: dd_Smed_v6_4172_0_4, dd_Smed_v6_4172_0_4, [Score=411, Expect=6e-137]} {RNA1509_23462} {RNA1310_21506} {RNA815_9702}
27. MligTC455_53189 1040 21.66 Mlig455_029623

Neo: -

Age: Down-Down-Up

2.597 0.813 - - 0.833 0.951 - Mlig455_029623 {REF} {Length: 1190} {Pfam: Globin [PF00042.24, score=53.3]} {Smed: dd_Smed_v6_19850_0_1, dd_Smed_v6_19850_0_1, [Score=45.4, Expect=8e-06]} {RNA1509_20726, RNA1509_38771, RNA1509_38994} {RNA1310_34513, RNA1509_20726, RNA1509_38771, RNA1509_38994} {RNA1509_20726, RNA1509_38771, RNA1509_38994, RNA815_16338}
28. MligTC455_52003 1043 21.73 Mlig455_050564, Mlig455_050571

Neo: -

Age: -

RGS4, RGS8 2.596 - - 0.788 0.968 0.840 -

Mlig455_050564 {REF} {Length: 3240} {Pfam: Regulator of G protein signaling domain [PF00615.21, score=116.7]} {Human: ENSG00000117152, RGS4, regulator of G protein signaling 4, [RH, Score=149, Expect=2e-42]} {Mouse: ENSMUSG00000038530, Rgs4, regulator of G-protein signaling 4, [RH, Score=153, Expect=4e-44]; ENSMUSG00000026678, Rgs5, regulator of G-protein signaling 5, [RH, Score=149, Expect=1e-42]; ENSMUSG00000042671, Rgs8, regulator of G-protein signaling 8, [RH, Score=149, Expect=1e-42]} {Dmel: FBgn0028743, Dhit, Double hit, [Score=118, Expect=2e-30]} {Celegans: WBGene00004350, rgs-7, Regulator of G-protein signaling rgs-7, [Score=124, Expect=4e-33]} {Smed: dd_Smed_v6_8648_0_1, dd_Smed_v6_8648_0_1, [RH, Score=199, Expect=4e-58]} {RNA1509_11015, RNA1509_27306} {RNA1310_4876, RNA1509_11015, RNA1509_27306} {RNA1509_11015, RNA1509_27306, RNA815_6054}

Mlig455_050571 {REF} {Length: 2222} {Pfam: Regulator of G protein signaling domain [PF00615.21, score=118.3]} {Human: ENSG00000135824, RGS8, regulator of G protein signaling 8, [RH, Score=149, Expect=9e-45]; ENSG00000117152, RGS4, regulator of G protein signaling 4, [RH, Score=149, Expect=2e-44]; ENSG00000150681, RGS18, regulator of G protein signaling 18, [RH, Score=146, Expect=5e-43]; ENSG00000143248, RGS5, regulator of G protein signaling 5, [RH, Score=144, Expect=7e-43]} {Mouse: ENSMUSG00000038530, Rgs4, regulator of G-protein signaling 4, [RH, Score=153, Expect=5e-46]; ENSMUSG00000042671, Rgs8, regulator of G-protein signaling 8, [RH, Score=151, Expect=1e-45]; ENSMUSG00000026678, Rgs5, regulator of G-protein signaling 5, [RH, Score=147, Expect=7e-44]} {Dmel: FBgn0028743, Dhit, Double hit, [Score=117, Expect=1e-31]} {Celegans: WBGene00004350, rgs-7, Regulator of G-protein signaling rgs-7, [Score=124, Expect=7e-35]} {Smed: dd_Smed_v6_8648_0_1, dd_Smed_v6_8648_0_1, [RH, Score=192, Expect=1e-57]} {RNA1509_27306} {RNA1310_5436.1} {RNA815_6054}
29. MligTC455_44050 2086 43.46 Mlig455_028045, Mlig455_028051

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.242

Region-specific R2: 6.161

Region-enriched R2: 7.072/0.00000
Region-enriched R3: 3.149/0.00025

2.593 0.747 - - - 0.965 0.881

Mlig455_028045 {REF} {Length: 1156} {RNA1509_31459, RNA1509_3903} {RNA1310_2730.2, RNA1509_31459, RNA1509_3903} {RNA1509_31459, RNA1509_3903, RNA815_7682}

Mlig455_028051 {REF} {Length: 871} {NoTransDecoderORF} {RNA1509_3903} {RNA1310_15260} {RNA815_7682}
30. MligTC455_46698 2235 46.56 Mlig455_009652

Neo: -

Age: Down-Up-Up

Region-enriched R2: 2.372/0.00045
Region-enriched R7: 2.057/0.00055

Regeneration-depleted TP: -3.177
Regeneration-depleted BL: -2.998

2.592 - - - 0.761 0.951 0.880 Mlig455_009652 {REF} {Length: 763} {Pfam: WD repeat binding protein EZH2 [PF11616.10, score=33.2]; NOPS (NUC059) domain [PF08075.13, score=29.1]} {RNA1509_45891} {RNA1310_92759} {RNA815_24028}
31. MligTC455_16739 628 13.08 Mlig455_040111

Neo: -

Age: logFC(26M/2M)=-0.328

Region-enriched R2: 3.456/0.01732
Region-enriched R5: 2.743/0.00527

Regeneration-downregulated R5: -4.251

Regeneration-depleted R5: -4.251

PCSK1 2.56 0.757 - - 0.970 0.833 - Mlig455_040111 {REF} {Length: 2929} {Pfam: Subtilase family [PF00082.24, score=160.6]; Proprotein convertase P-domain [PF01483.22, score=87.0]; Peptidase S8 pro-domain [PF16470.7, score=50.0]} {Human: ENSG00000175426, PCSK1, proprotein convertase subtilisin/kexin type 1, [RH, Score=550, Expect=0.0]} {Mouse: ENSMUSG00000021587, Pcsk1, proprotein convertase subtilisin/kexin type 1, [RH, Score=550, Expect=0.0]} {Dmel: FBgn0004598, Fur2, Furin 2, [Score=483, Expect=1e-152]} {Celegans: WBGene00002232, kpc-1, Furin-like protease kpc-1, [Score=468, Expect=3e-156]} {Smed: dd_Smed_v6_8406_0_1, dd_Smed_v6_8406_0_1, [RH, Score=474, Expect=2e-159]} {RNA1509_20395} {RNA1310_6257} {RNA815_2270.1}
32. MligTC455_48609 3538 73.7 Mlig455_037431, Mlig455_037454, Mlig455_037501

Neo: -

Age: -

Region-specific R2: 3.134

Region-enriched R2: 1.985/0.00000

Regeneration-downregulated BL: -2.003

Regeneration-depleted BL: -2.003

CAPN5 2.533 0.736 - - - 0.954 0.843

Mlig455_037431 {REF} {Length: 2455} {Pfam: Calpain family cysteine protease [PF00648.23, score=124.0]} {Human: ENSG00000149260, CAPN5, calpain 5, [Score=106, Expect=2e-23]} {Mouse: ENSMUSG00000035547, Capn5, calpain 5, [Score=103, Expect=1e-22]} {Dmel: FBgn0012051, CalpA, Calpain-A, [Score=86.3, Expect=2e-17]} {Celegans: WBGene00006606, tra-3, Calpain-5, [Score=120, Expect=2e-28]} {Smed: dd_Smed_v6_8673_0_1, dd_Smed_v6_8673_0_1, [Score=103, Expect=5e-23]} {RNA1509_27234} {RNA1310_12131} {RNA815_7478.1}

Mlig455_037454 {REF} {Length: 1043} {RNA1509_15549} {RNA1310_57168} {RNA815_30048}

Mlig455_037501 {REF} {Length: 2687} {Pfam: Calpain family cysteine protease [PF00648.23, score=123.7]} {Human: ENSG00000149260, CAPN5, calpain 5, [Score=108, Expect=6e-24]} {Mouse: ENSMUSG00000035547, Capn5, calpain 5, [Score=105, Expect=5e-23]} {Dmel: FBgn0012051, CalpA, Calpain-A, [Score=86.3, Expect=2e-17]} {Celegans: WBGene00006606, tra-3, Calpain-5, [Score=120, Expect=3e-28]} {Smed: dd_Smed_v6_8673_0_1, dd_Smed_v6_8673_0_1, [Score=104, Expect=4e-23]} {RNA1509_27234} {RNA1310_12131} {RNA815_7478.1}
33. MligTC455_41013 3291 68.57 Mlig455_040499

Neo: -

Age: -

CCDC173 2.518 - - 0.754 - 0.952 0.812 Mlig455_040499 {REF} {Length: 2101} {Pfam: Trichohyalin-plectin-homology domain [PF13868.8, score=68.5]} {Human: ENSG00000154479, CCDC173, coiled-coil domain containing 173, [Score=163, Expect=5e-43]} {Mouse: ENSMUSG00000070883, Ccdc173, coiled-coil domain containing 173, [Score=134, Expect=5e-33]} {Smed: dd_Smed_v6_8917_0_1, dd_Smed_v6_8917_0_1, [Score=337, Expect=3e-109]} {RNA1509_12182, RNA1509_1409} {RNA1310_8545.2, RNA1509_12182} {RNA1509_12182, RNA815_4498}
34. MligTC455_14685 3975 82.82 Mlig455_051429

Neo: -

Age: -

Region-specific R2: 2.895

Region-enriched R2: 2.262/0.00004

PAM 2.501 - 0.704 - - 0.958 0.839 Mlig455_051429 {REF} {Length: 1911} {Pfam: NHL repeat [PF01436.23, score=59.1]} {Human: ENSG00000145730, PAM, peptidylglycine alpha-amidating monooxygenase, [Score=119, Expect=2e-28]} {Mouse: ENSMUSG00000026335, Pam, peptidylglycine alpha-amidating monooxygenase, [Score=115, Expect=2e-27]} {Dmel: FBgn0262728, Pal2, Peptidyl-alpha-hydroxyglycine-alpha-amidating lyase 2, [Score=115, Expect=2e-28]} {Celegans: WBGene00017671, pgal-1, Probable peptidyl-alpha-hydroxyglycine alpha-amidating lyase pgal-1, [Score=125, Expect=2e-32]} {Smed: dd_Smed_v6_3093_0_1, dd_Smed_v6_3093_0_1, [Score=138, Expect=4e-37]} {RNA1509_910} {RNA1310_18216.1} {RNA815_736.1}
35. MligTC455_52210 5661 117.93 Mlig455_005609, Mlig455_014449, Mlig455_070190

Neo: -

Age: -

2.48 0.733 - - 0.969 0.778 -

Mlig455_005609 {REF} {Length: 747} {Pfam: Domain of unknown function (DUF4573) [PF15140.8, score=23.9]} {RNA1509_54058} {RNA1310_50049} {RNA815_23688.1}

Mlig455_014449 {REF} {Length: 881} {Pfam: Domain of unknown function (DUF4573) [PF15140.8, score=22.6]} {RNA1509_54058} {RNA1310_50296} {RNA815_23688.1}

Mlig455_070190 {REF} {Length: 692} {Pfam: Domain of unknown function (DUF4573) [PF15140.8, score=20.8]} {RNA1509_54058} {RNA1310_50296} {RNA815_23688.2}
36. MligTC455_43326 39 0.8 Mlig455_057987

Neo: -

Age: -

2.455 - - - 0.958 0.750 0.747 Mlig455_057987 {REF} {Length: 1058} {RNA1310_129308}
37. MligTC455_45173 1421 29.61 Mlig455_000256

Neo: -

Age: Up-Down-Up

Region-enriched R2: 2.313/0.00035

2.424 - - - 0.717 0.957 0.750 Mlig455_000256 {REF} {Length: 574} {RNA1509_48066} {RNA1310_71808.1} {RNA815_32033}
38. MligTC455_45174 1447 30.15 Mlig455_058539

Neo: -

Age: -

Region-enriched R2: 2.293/0.00024

MLX 2.423 - - - 0.717 0.954 0.752 Mlig455_058539 {REF} {Length: 4178} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=41.6]} {Human: ENSG00000108788, MLX, MLX, MAX dimerization protein, [RH, Score=145, Expect=5e-42]} {Mouse: ENSMUSG00000017801, Mlx, MAX-like protein X, [RH, Score=144, Expect=8e-42]} {Dmel: FBgn0039509, bigmax, [RH, Score=130, Expect=2e-36]} {Smed: dd_Smed_v6_3140_0_1, dd_Smed_v6_3140_0_1, [RH, Score=163, Expect=3e-48]} {RNA1509_10793} {RNA1310_22883.1, RNA1509_10793} {RNA1509_10793, RNA815_10829}
39. MligTC455_35411 583 12.15 Mlig455_064235

Neo: -

Age: -

PPP3CA 1.893 - - - 0.934 0.959 - Mlig455_064235 {REF} {Length: 3595} {Human: ENSG00000138814, PPP3CA, protein phosphatase 3 catalytic subunit alpha, [Score=156, Expect=8e-46]; ENSG00000107758, PPP3CB, protein phosphatase 3 catalytic subunit beta, [Score=149, Expect=4e-43]} {Mouse: ENSMUSG00000028161, Ppp3ca, protein phosphatase 3, catalytic subunit, alpha isoform, [Score=158, Expect=1e-46]} {Dmel: FBgn0011826, Pp2B-14D, Protein phosphatase 2B at 14D, [Score=159, Expect=1e-46]} {Celegans: WBGene00006527, tax-6, Serine/threonine-protein phosphatase 2B catalytic subunit, [Score=115, Expect=1e-30]} {Smed: dd_Smed_v6_5669_1_2, dd_Smed_v6_5669_1_2, [Score=155, Expect=7e-49]} {RNA1509_42566} {RNA1310_30586} {RNA815_21103.2}
40. MligTC455_40444 2996 62.42 Mlig455_039527, Mlig455_051318

Neo: -

Age: Down-Up-Down

1.867 - - - - 0.957 0.910

Mlig455_039527 {REF} {Length: 710} {RNA1509_7655} {RNA1310_63393} {RNA815_30324}

Mlig455_051318 {REF} {Length: 721} {RNA1509_7655} {RNA1310_63393, RNA1509_7655} {RNA1509_7655, RNA815_30324}
41. MligTC455_12131 23 0.47 Mlig455_013913

Neo: -

Age: -

1.853 - - - 0.958 0.895 - Mlig455_013913 {REF} {Length: 1451} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=38.4]} {Smed: dd_Smed_v6_33525_0_1, dd_Smed_v6_33525_0_1, [Score=115, Expect=4e-30]} {RNA1310_68929} {RNA815_54261}
42. MligTC455_14516 344 7.17 Mlig455_006080, Mlig455_068033

Neo: -

Age: -

Region-enriched R2: 2.671/0.04041

1.852 - - - 0.969 0.883 -

Mlig455_006080 {REF} {Length: 1977} {RNA1509_31100} {RNA1310_11196} {RNA815_24298}

Mlig455_068033 {REF} {Length: 2488} {RNA1509_31100} {RNA1310_11196, RNA1509_31100} {RNA1509_31100, RNA815_24298}
43. MligTC455_50601 21 0.44 Mlig455_018462

Neo: -

Age: -

1.844 - - - 0.889 0.955 - Mlig455_018462 {REF} {Length: 2878} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=164.0]} {Smed: dd_Smed_v6_37545_0_1, dd_Smed_v6_37545_0_1, [Score=117, Expect=1e-27]} {RNA1310_8235} {RNA815_10456.1}
44. MligTC455_35410 528 11 Mlig455_064178

Neo: -

Age: Down-Down-Down

Region-enriched R2: 2.241/0.03122

PPP3CA 1.82 - - - 0.982 0.838 - Mlig455_064178 {REF} {Length: 4178} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=129.2]} {Human: ENSG00000138814, PPP3CA, protein phosphatase 3 catalytic subunit alpha, [Score=701, Expect=0.0]; ENSG00000107758, PPP3CB, protein phosphatase 3 catalytic subunit beta, [Score=690, Expect=0.0]; ENSG00000120910, PPP3CC, protein phosphatase 3 catalytic subunit gamma, [Score=673, Expect=0.0]} {Mouse: ENSMUSG00000028161, Ppp3ca, protein phosphatase 3, catalytic subunit, alpha isoform, [Score=703, Expect=0.0]; ENSMUSG00000021816, Ppp3cb, protein phosphatase 3, catalytic subunit, beta isoform, [Score=690, Expect=0.0]} {Dmel: FBgn0267912, CanA-14F, Calcineurin A at 14F, [Score=697, Expect=0.0]} {Celegans: WBGene00006527, tax-6, Serine/threonine-protein phosphatase 2B catalytic subunit, [Score=646, Expect=0.0]} {Smed: dd_Smed_v6_5378_0_1, dd_Smed_v6_5378_0_1, [Score=523, Expect=0.0]} {RNA1509_25279} {RNA1310_17931} {RNA815_6996}
45. MligTC455_43509 1526 31.78 Mlig455_024779, Mlig455_066104, Mlig455_068669

Neo: -

Age: Down-Up-Up

ACSL1 1.813 - - - - 0.953 0.860

Mlig455_024779 {REF} {Length: 2596} {Pfam: AMP-binding enzyme [PF00501.30, score=343.5]; AMP-binding enzyme C-terminal domain [PF13193.8, score=23.4]} {Human: ENSG00000151726, ACSL1, acyl-CoA synthetase long chain family member 1, [Score=534, Expect=0.0]; ENSG00000164398, ACSL6, acyl-CoA synthetase long chain family member 6, [Score=518, Expect=1e-175]; ENSG00000197142, ACSL5, acyl-CoA synthetase long chain family member 5, [Score=514, Expect=2e-174]} {Mouse: ENSMUSG00000018796, Acsl1, acyl-CoA synthetase long-chain family member 1, [Score=515, Expect=9e-175]; ENSMUSG00000024981, Acsl5, acyl-CoA synthetase long-chain family member 5, [Score=513, Expect=6e-174]; ENSMUSG00000020333, Acsl6, acyl-CoA synthetase long-chain family member 6, [Score=509, Expect=3e-172]} {Dmel: FBgn0036821, CG3961, [RH, Score=552, Expect=0.0]} {Celegans: WBGene00013575, acs-5, Fatty Acid CoA Synthetase family, [Score=476, Expect=4e-160]} {Smed: dd_Smed_v6_2009_0_2, dd_Smed_v6_2009_0_2, [Score=427, Expect=5e-141]} {RNA1509_51374} {RNA1310_7356.1} {RNA815_5550.1}

Mlig455_066104 {REF} {Length: 2816} {Pfam: AMP-binding enzyme [PF00501.30, score=343.8]; AMP-binding enzyme C-terminal domain [PF13193.8, score=23.5]} {Human: ENSG00000151726, ACSL1, acyl-CoA synthetase long chain family member 1, [Score=531, Expect=1e-180]; ENSG00000197142, ACSL5, acyl-CoA synthetase long chain family member 5, [Score=516, Expect=3e-175]; ENSG00000164398, ACSL6, acyl-CoA synthetase long chain family member 6, [Score=513, Expect=1e-173]} {Mouse: ENSMUSG00000018796, Acsl1, acyl-CoA synthetase long-chain family member 1, [Score=512, Expect=2e-173]; ENSMUSG00000024981, Acsl5, acyl-CoA synthetase long-chain family member 5, [Score=511, Expect=4e-173]; ENSMUSG00000020333, Acsl6, acyl-CoA synthetase long-chain family member 6, [Score=506, Expect=5e-171]} {Dmel: FBgn0036821, CG3961, [RH, Score=551, Expect=0.0]} {Celegans: WBGene00013575, acs-5, Fatty Acid CoA Synthetase family, [Score=476, Expect=6e-160]} {Smed: dd_Smed_v6_2009_0_2, dd_Smed_v6_2009_0_2, [Score=424, Expect=7e-140]} {RNA1509_21029, RNA1509_51374} {RNA1310_7356.1, RNA1509_21029, RNA1509_51374} {RNA1509_21029, RNA1509_51374, RNA815_5550.1}

Mlig455_068669 {REF} {Length: 2627} {Pfam: AMP-binding enzyme [PF00501.30, score=343.5]; AMP-binding enzyme C-terminal domain [PF13193.8, score=23.4]} {Human: ENSG00000151726, ACSL1, acyl-CoA synthetase long chain family member 1, [Score=534, Expect=0.0]; ENSG00000164398, ACSL6, acyl-CoA synthetase long chain family member 6, [Score=518, Expect=1e-175]; ENSG00000197142, ACSL5, acyl-CoA synthetase long chain family member 5, [Score=514, Expect=2e-174]} {Mouse: ENSMUSG00000018796, Acsl1, acyl-CoA synthetase long-chain family member 1, [Score=515, Expect=9e-175]; ENSMUSG00000024981, Acsl5, acyl-CoA synthetase long-chain family member 5, [Score=513, Expect=6e-174]; ENSMUSG00000020333, Acsl6, acyl-CoA synthetase long-chain family member 6, [Score=509, Expect=3e-172]} {Dmel: FBgn0036821, CG3961, [RH, Score=552, Expect=0.0]} {Celegans: WBGene00013575, acs-5, Fatty Acid CoA Synthetase family, [Score=476, Expect=4e-160]} {Smed: dd_Smed_v6_2009_0_2, dd_Smed_v6_2009_0_2, [Score=427, Expect=5e-141]} {RNA1509_51374} {RNA1310_7356.1} {RNA815_5550.1}
46. MligTC455_25112 611 12.74 Mlig455_020700

Neo: -

Age: Down-Down-Up

Region-enriched R7: 1.981/0.01296

1.805 - - 0.843 - 0.962 - Mlig455_020700 {REF} {Length: 831} {Celegans: WBGene00003748, nlp-10, Neuropeptide-Like Protein, [Score=46.6, Expect=8e-07]} {RNA1509_27832, RNA1509_36958} {RNA1310_50245, RNA1509_27832, RNA1509_36958} {RNA1509_27832, RNA1509_36958, RNA815_48543}
47. MligTC455_49557 280 5.82 Mlig455_017273

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.728

Region-specific R2: 3.642

Region-enriched R2: 3.187/0.00196

1.796 - - - 0.967 0.829 - Mlig455_017273 {REF} {Length: 1333} {RNA1509_52848} {RNA1310_64923, RNA1509_52848} {RNA1509_52848, RNA815_51063}
48. MligTC455_46885 72 1.49 Mlig455_015138

Neo: -

Age: -

PRKG2 1.789 - - - 0.972 0.817 - Mlig455_015138 {REF} {Length: 3064} {Pfam: Protein kinase domain [PF00069.27, score=227.4]; Cyclic nucleotide-binding domain [PF00027.31, score=128.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=118.5]; Kinase-like [PF14531.8, score=25.1]} {Human: ENSG00000138669, PRKG2, protein kinase cGMP-dependent 2, [RH, Score=674, Expect=0.0]} {Mouse: ENSMUSG00000029334, Prkg2, protein kinase, cGMP-dependent, type II, [RH, Score=674, Expect=0.0]} {Dmel: FBgn0000442, Pkg21D, Protein kinase, cGMP-dependent at 21D, [RH, Score=682, Expect=0.0]} {Celegans: WBGene00001173, egl-4, cGMP-dependent protein kinase egl-4, [Score=668, Expect=0.0]} {Smed: dd_Smed_v6_6967_0_1, dd_Smed_v6_6967_0_1, [RH, Score=676, Expect=0.0]} {RNA1509_26653} {RNA1310_15330.1} {RNA815_26005}
49. MligTC455_23269 1700 35.41 Mlig455_058823

Neo: -

Age: -

Region-enriched R8: 1.965/0.00066

SYT1 1.786 - - - 0.831 0.955 - Mlig455_058823 {REF} {Length: 3328} {Pfam: C2 domain [PF00168.32, score=181.3]; CEP76 C2 domain [PF15627.8, score=21.0]; Phosphoinositide 3-kinase C2 [PF00792.26, score=20.4]} {Human: ENSG00000067715, SYT1, synaptotagmin 1, [RH, Score=436, Expect=4e-151]} {Mouse: ENSMUSG00000035864, Syt1, synaptotagmin I, [RH, Score=435, Expect=4e-151]} {Dmel: FBgn0004242, Syt1, Synaptotagmin 1, [Score=496, Expect=1e-174]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=432, Expect=6e-150]} {Smed: dd_Smed_v6_6730_0_1, dd_Smed_v6_6730_0_1, [Score=542, Expect=0.0]} {RNA1509_10517, RNA1509_25740, RNA1509_36281, RNA1509_40080} {RNA1310_21689, RNA1509_10517, RNA1509_25740, RNA1509_36281, RNA1509_40080} {RNA1509_10517, RNA1509_25740, RNA1509_36281, RNA1509_40080, RNA815_10622.1}
50. MligTC455_16532 296 6.16 Mlig455_052809

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=3.244

Region-enriched R4: 7.266/0.00432

1.773 - - - 0.952 - 0.821 Mlig455_052809 {REF} {Length: 1999} {RNA1310_91481} {RNA815_48057}
51. MligTC455_48128 18 0.37 Mlig455_052326

Neo: -

Age: -

1.771 - - - 0.957 0.814 - Mlig455_052326 {REF} {Length: 3582} {RNA1310_42908} {RNA815_22744}
52. MligTC455_49855 19 0.39 Mlig455_020555, Mlig455_020604

Neo: -

Age: -

1.746 - - - 0.955 - 0.791

Mlig455_020555 {REF} {Length: 1515} {RNA1509_44515} {RNA1310_26152} {RNA815_8882}

Mlig455_020604 {REF} {Length: 370} {Pfam: PAN domain [PF00024.28, score=19.8]} {RNA1509_44515} {RNA1310_26152} {RNA815_8882}
53. MligTC455_37005 759 15.82 Mlig455_062895

Neo: -

Age: logFC(26M/2M)=-0.530

Region-enriched R2: 2.906/0.01531
Region-enriched R6: 2.551/0.00476

SLC5A12 1.741 0.770 - - 0.971 - - Mlig455_062895 {REF} {Length: 3080} {Pfam: Sodium:solute symporter family [PF00474.19, score=141.8]} {Human: ENSG00000148942, SLC5A12, solute carrier family 5 member 12, [RH, Score=452, Expect=1e-151]; ENSG00000256870, SLC5A8, solute carrier family 5 member 8, [RH, Score=444, Expect=1e-148]; ENSG00000262217, SLC5A8, solute carrier family 5 member 8, [RH, Score=444, Expect=1e-148]} {Mouse: ENSMUSG00000041644, Slc5a12, solute carrier family 5 (sodium/glucose cotransporter), member 12, [RH, Score=458, Expect=4e-154]; ENSMUSG00000020062, Slc5a8, solute carrier family 5 (iodide transporter), member 8, [RH, Score=436, Expect=1e-145]} {Dmel: FBgn0034494, CG10444, [RH, Score=412, Expect=6e-137]} {Celegans: WBGene00014092, ZK822.5, [RH, Score=273, Expect=2e-83]} {Smed: dd_Smed_v6_14173_0_1, dd_Smed_v6_14173_0_1, [RH, Score=481, Expect=6e-164]} {RNA1509_28319, RNA1509_8499} {RNA1310_12282.1, RNA1509_28319, RNA1509_8499} {RNA1509_28319, RNA1509_8499, RNA815_4467}
54. MligTC455_52814 47 0.97 Mlig455_047356, Mlig455_047365

Neo: -

Age: -

CNTN2 1.728 - - - 0.962 0.766 -

Mlig455_047356 {REF} {Length: 2537} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=57.8]; Immunoglobulin domain [PF13927.8, score=52.6]; Immunoglobulin domain [PF13895.8, score=40.4]; Immunoglobulin domain [PF00047.27, score=40.3]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=25.9]} {Human: ENSG00000184144, CNTN2, contactin 2, [Score=58.5, Expect=3e-08]} {Mouse: ENSMUSG00000053024, Cntn2, contactin 2, [Score=56.6, Expect=8e-08]; ENSMUSG00000061751, Kalrn, kalirin, RhoGEF kinase, [Score=55.1, Expect=2e-07]; ENSMUSG00000020674, Pxdn, peroxidasin, [Score=54.7, Expect=3e-07]} {Dmel: FBgn0264975, Nrg, Neuroglian, [Score=58.2, Expect=2e-08]} {Smed: dd_Smed_v6_15129_0_1, dd_Smed_v6_15129_0_1, [RH, Score=99.8, Expect=2e-22]} {RNA1509_60115} {RNA1310_31768} {RNA815_18728}

Mlig455_047365 {REF} {Length: 3489} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=57.9]; Immunoglobulin domain [PF13927.8, score=52.8]; Immunoglobulin domain [PF13895.8, score=40.5]; Immunoglobulin domain [PF00047.27, score=40.3]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=26.4]} {Human: ENSG00000184144, CNTN2, contactin 2, [Score=57.4, Expect=5e-08]} {Mouse: ENSMUSG00000053024, Cntn2, contactin 2, [Score=55.5, Expect=1e-07]; ENSMUSG00000020674, Pxdn, peroxidasin, [Score=53.9, Expect=5e-07]; ENSMUSG00000061751, Kalrn, kalirin, RhoGEF kinase, [Score=53.5, Expect=6e-07]; ENSMUSG00000055022, Cntn1, contactin 1, [Score=52.8, Expect=1e-06]; ENSMUSG00000030075, Cntn3, contactin 3, [Score=52.8, Expect=1e-06]} {Dmel: FBgn0264975, Nrg, Neuroglian, [Score=55.5, Expect=1e-07]} {Smed: dd_Smed_v6_15129_0_1, dd_Smed_v6_15129_0_1, [RH, Score=99.8, Expect=1e-22]} {RNA1509_60115} {RNA1310_31768} {RNA815_19521}
55. MligTC455_52238 282 5.87 Mlig455_029211

Neo: -

Age: logFC(26M/2M)=-0.312

ABCG2 1.719 - - - 0.954 0.765 - Mlig455_029211 {REF} {Length: 3240} {Human: ENSG00000118777, ABCG2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=80.5, Expect=3e-15]} {Mouse: ENSMUSG00000029802, Abcg2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=79.0, Expect=7e-15]} {Smed: dd_Smed_v6_4225_0_1, dd_Smed_v6_4225_0_1, [Score=108, Expect=2e-24]} {RNA1509_38878} {RNA1310_949.2} {RNA815_1895}
56. MligTC455_25516 623 12.97 Mlig455_036379, Mlig455_054584

Neo: -

Age: -

1.717 - - 0.765 - 0.952 -

Mlig455_036379 {REF} {Length: 3088} {RNA1509_28479, RNA1509_52708} {RNA1310_4011, RNA1509_52708} {RNA1509_52708, RNA815_18281.1}

Mlig455_054584 {REF} {Length: 3410} {RNA1509_28479} {RNA1310_4011} {RNA815_18281.1}
57. MligTC455_25517 301 6.28 Mlig455_036413

Neo: -

Age: Up-Down-Up

1.715 - - 0.764 - 0.951 - Mlig455_036413 {REF} {Length: 1873} {RNA1509_52708} {RNA1310_4011} {RNA815_18281.1}
58. MligTC455_09916 99 2.06 Mlig455_041793

Neo: -

Age: Up-Down-Up

SLC24A3 1.694 - - - 0.960 0.734 - Mlig455_041793 {REF} {Length: 2836} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=164.2]} {Human: ENSG00000185052, SLC24A3, solute carrier family 24 member 3, [Score=273, Expect=3e-81]; ENSG00000140090, SLC24A4, solute carrier family 24 member 4, [Score=272, Expect=4e-81]; ENSG00000155886, SLC24A2, solute carrier family 24 member 2, [Score=266, Expect=1e-78]} {Mouse: ENSMUSG00000037996, Slc24a2, solute carrier family 24 (sodium/potassium/calcium exchanger), member 2, [Score=271, Expect=7e-80]; ENSMUSG00000063873, Slc24a3, solute carrier family 24 (sodium/potassium/calcium exchanger), member 3, [Score=268, Expect=5e-80]; ENSMUSG00000041771, Slc24a4, solute carrier family 24 (sodium/potassium/calcium exchanger), member 4, [Score=267, Expect=1e-79]} {Dmel: FBgn0028704, Nckx30C, [Score=256, Expect=1e-73]} {Celegans: WBGene00003569, ncx-4, Na/Ca eXchangers, [Score=143, Expect=9e-36]} {Smed: dd_Smed_v6_9736_0_1, dd_Smed_v6_9736_0_1, [Score=285, Expect=1e-86]} {RNA1310_23810} {RNA815_17580}
59. MligTC455_43352 95 1.98 Mlig455_036042, Mlig455_036143, Mlig455_036169

Neo: -

Age: -

1.694 - - - 0.975 0.719 -

Mlig455_036042 {REF} {Length: 601} {NoTransDecoderORF} {RNA1310_52240} {RNA815_32818}

Mlig455_036143 {REF} {Length: 706} {RNA1310_52240} {RNA815_32818}

Mlig455_036169 {REF} {Length: 944} {NoTransDecoderORF} {RNA1310_52240} {RNA815_32818}
60. MligTC455_45020 386 8.05 Mlig455_012422

Neo: -

Age: -

Region-enriched R2: 4.067/0.00066
Region-enriched R3: 2.869/0.01291

AVP 1.691 - - - - 0.962 0.729 Mlig455_012422 {REF} {Length: 1252} {Pfam: Neurohypophysial hormones, C-terminal Domain [PF00184.19, score=36.0]} {Human: ENSG00000101200, AVP, arginine vasopressin, [Score=50.4, Expect=4e-08]} {Mouse: ENSMUSG00000037727, Avp, arginine vasopressin, [Score=52.0, Expect=7e-09]} {RNA1509_50574} {RNA1310_26737, RNA1509_50574} {RNA1509_50574, RNA815_23813}
61. MligTC455_53037 13249 276.01 Mlig455_032646

Neo: -

Age: -

1.691 - - - 0.722 - 0.969 Mlig455_032646 {REF} {Length: 968} {RNA1509_30269, RNA1509_4133, RNA1509_8761} {RNA1310_40499.1, RNA1509_30269, RNA1509_4133, RNA1509_8761} {RNA1509_30269, RNA1509_4133, RNA1509_8761, RNA815_19419.1}
62. MligTC455_49593 323 6.72 Mlig455_025219

Neo: -

Age: Up-Down-Up

Region-enriched R2: 3.432/0.00265
Region-enriched R6: 2.411/0.04695

RRBP1 1.689 - - - 0.727 0.962 - Mlig455_025219 {REF} {Length: 1413} {Human: ENSG00000125844, RRBP1, ribosome binding protein 1, [RH, Score=62.8, Expect=2e-11]} {RNA1509_39523} {RNA1310_52655} {RNA815_22785}
63. MligTC455_46173 63 1.3 Mlig455_032091

Neo: Irradiation

Age: Up-Down-Up

SRR 1.682 - - - 0.730 0.952 - Mlig455_032091 {REF} {Length: 2590} {Pfam: Pyridoxal-phosphate dependent enzyme [PF00291.27, score=208.5]; ACT domain [PF01842.27, score=19.8]} {Human: ENSG00000167720, SRR, serine racemase, [Score=129, Expect=2e-32]} {Mouse: ENSMUSG00000001323, Srr, serine racemase, [Score=105, Expect=4e-24]} {Dmel: FBgn0037684, CG8129, [Score=373, Expect=5e-123]} {Celegans: WBGene00010456, K01C8.1, [Score=407, Expect=5e-136]} {Smed: dd_Smed_v6_6737_0_1, dd_Smed_v6_6737_0_1, [Score=474, Expect=7e-163]} {RNA1509_48789} {RNA1310_15074} {RNA815_9364}
64. MligTC455_27673 123 2.56 Mlig455_041241, Mlig455_053095

Neo: -

Age: Up-Down-Up

GLRA1, GLRA3 1.657 - - - 0.707 0.950 -

Mlig455_041241 {REF} {Length: 4857} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=165.7]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=84.7]} {Human: ENSG00000145451, GLRA3, glycine receptor alpha 3, [Score=253, Expect=3e-78]; ENSG00000145888, GLRA1, glycine receptor alpha 1, [Score=249, Expect=9e-77]; ENSG00000101958, GLRA2, glycine receptor alpha 2, [Score=246, Expect=1e-75]} {Mouse: ENSMUSG00000018589, Glra2, glycine receptor, alpha 2 subunit, [Score=246, Expect=7e-76]; ENSMUSG00000038257, Glra3, glycine receptor, alpha 3 subunit, [Score=244, Expect=2e-74]; ENSMUSG00000000263, Glra1, glycine receptor, alpha 1 subunit, [Score=243, Expect=1e-74]; ENSMUSG00000018595, Glra4, glycine receptor, alpha 4 subunit, [Score=240, Expect=2e-73]} {Dmel: FBgn0024963, GluClalpha, [Score=256, Expect=1e-79]} {Celegans: WBGene00000233, avr-15, GluClalpha2B protein, [RH, Score=247, Expect=6e-76]} {Smed: dd_Smed_v6_11342_0_1, dd_Smed_v6_11342_0_1, [RH, Score=440, Expect=1e-151]} {RNA1509_35986} {RNA1310_28655} {RNA815_20247}

Mlig455_053095 {REF} {Length: 4892} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=163.1]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=83.4]} {Human: ENSG00000145888, GLRA1, glycine receptor alpha 1, [Score=254, Expect=9e-79]; ENSG00000145451, GLRA3, glycine receptor alpha 3, [Score=251, Expect=1e-77]; ENSG00000101958, GLRA2, glycine receptor alpha 2, [Score=243, Expect=9e-75]} {Mouse: ENSMUSG00000000263, Glra1, glycine receptor, alpha 1 subunit, [Score=248, Expect=9e-77]; ENSMUSG00000018589, Glra2, glycine receptor, alpha 2 subunit, [Score=244, Expect=5e-75]; ENSMUSG00000038257, Glra3, glycine receptor, alpha 3 subunit, [Score=242, Expect=4e-74]; ENSMUSG00000018595, Glra4, glycine receptor, alpha 4 subunit, [Score=236, Expect=2e-72]} {Dmel: FBgn0024963, GluClalpha, [Score=257, Expect=4e-80]} {Celegans: WBGene00000233, avr-15, GluClalpha2B protein, [Score=252, Expect=3e-78]} {Smed: dd_Smed_v6_11342_0_1, dd_Smed_v6_11342_0_1, [Score=449, Expect=1e-155]} {RNA1509_54479} {RNA1310_56579} {RNA815_20247}
65. MligTC455_16311 89 1.86 Mlig455_053827, Mlig455_068518

Neo: -

Age: -

Region-enriched R2: 5.249/0.01530

CALML3 0.968 - - - 0.968 - -

Mlig455_053827 {REF} {Length: 1659} {Pfam: EF-hand domain pair [PF13499.8, score=64.3]; EF hand [PF00036.34, score=58.1]; EF-hand domain [PF13405.8, score=55.1]; EF hand [PF13202.8, score=37.9]; EF-hand domain pair [PF13833.8, score=32.8]; EF-hand domain [PF14658.8, score=20.4]} {Human: ENSG00000178363, CALML3, calmodulin like 3, [Score=96.7, Expect=3e-25]; ENSG00000143933, CALM2, calmodulin 2, [Score=96.7, Expect=6e-25]; ENSG00000198668, CALM1, calmodulin 1, [Score=96.3, Expect=3e-25]; ENSG00000160014, CALM3, calmodulin 3, [Score=96.3, Expect=3e-25]} {Mouse: ENSMUSG00000036438, Calm2, calmodulin 2, [Score=96.3, Expect=2e-25]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=96.3, Expect=2e-25]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=96.3, Expect=2e-25]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=95.9, Expect=2e-25]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=97.1, Expect=7e-26]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=97.4, Expect=5e-26]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=97.4, Expect=4e-26]} {RNA1509_37850} {RNA1310_5623.1} {RNA815_35579}

Mlig455_068518 {REF} {Length: 1007} {Pfam: EF-hand domain pair [PF13499.8, score=64.3]; EF hand [PF00036.34, score=58.1]; EF-hand domain [PF13405.8, score=55.1]; EF hand [PF13202.8, score=38.0]; EF-hand domain pair [PF13833.8, score=33.0]; EF-hand domain [PF14658.8, score=20.4]} {Human: ENSG00000178363, CALML3, calmodulin like 3, [Score=96.7, Expect=2e-25]; ENSG00000143933, CALM2, calmodulin 2, [Score=96.7, Expect=6e-25]; ENSG00000160014, CALM3, calmodulin 3, [Score=96.3, Expect=3e-25]; ENSG00000198668, CALM1, calmodulin 1, [Score=96.3, Expect=3e-25]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=96.3, Expect=2e-25]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=96.3, Expect=2e-25]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=96.3, Expect=2e-25]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=95.9, Expect=3e-25]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=97.1, Expect=7e-26]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=97.1, Expect=5e-26]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=97.1, Expect=4e-26]} {RNA1509_37850} {RNA1310_5623.1} {RNA815_35579}
66. MligTC455_54231 270 5.62 Mlig455_059344

Neo: -

Age: logFC(26M/2M)=-0.427

0.968 - - - 0.968 - - Mlig455_059344 {REF} {Length: 1419} {RNA1310_28936} {RNA815_10014.1}
67. MligTC455_07851 152 3.16 Mlig455_000950

Neo: -

Age: -

Region-enriched R4: 5.566/0.00142

0.965 - - - - 0.965 - Mlig455_000950 {REF} {Length: 404} {NoTransDecoderORF}
68. MligTC455_17002 37 0.76 Mlig455_011001

Neo: -

Age: logFC(26M/2M)=-1.400

P2RX2 0.963 - - - 0.963 - - Mlig455_011001 {REF} {Length: 3286} {Pfam: ATP P2X receptor [PF00864.21, score=289.2]} {Human: ENSG00000187848, P2RX2, purinergic receptor P2X 2, [Score=207, Expect=3e-60]; ENSG00000135124, P2RX4, purinergic receptor P2X 4, [Score=201, Expect=5e-59]} {Mouse: ENSMUSG00000029503, P2rx2, purinergic receptor P2X, ligand-gated ion channel, 2, [Score=202, Expect=9e-59]; ENSMUSG00000022758, P2rx6, purinergic receptor P2X, ligand-gated ion channel, 6, [Score=192, Expect=8e-56]} {Smed: dd_Smed_v6_10968_0_1, dd_Smed_v6_10968_0_1, [Score=270, Expect=2e-84]} {RNA1509_50956} {RNA1310_31414} {RNA815_43099}
69. MligTC455_14654 67 1.39 Mlig455_015424

Neo: -

Age: -

0.962 - - - 0.962 - - Mlig455_015424 {REF} {Length: 1213} {Pfam: Ectodermal ciliogenesis protein [PF15795.7, score=76.8]} {RNA1310_42665.1} {RNA815_17724}
70. MligTC455_06842 6 0.12 Mlig455_013891

Neo: -

Age: -

0.961 - - - - 0.961 - Mlig455_013891 {REF} {Length: 1062} {NoTransDecoderORF} {RNA1310_141190}
71. MligTC455_29690 6 0.12 Mlig455_038056

Neo: -

Age: -

TANC2 0.961 - - - - 0.961 - Mlig455_038056 {REF} {Length: 4719} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=57.4]; Ankyrin repeats (many copies) [PF13637.8, score=56.9]; Ankyrin repeat [PF13606.8, score=44.8]; Mab-21 protein [PF03281.16, score=44.1]; Ankyrin repeats (many copies) [PF13857.8, score=38.6]; Ankyrin repeat [PF00023.32, score=35.0]} {Human: ENSG00000170921, TANC2, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2, [Score=72.8, Expect=3e-12]} {Mouse: ENSMUSG00000053580, Tanc2, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2, [Score=70.5, Expect=1e-11]} {Dmel: FBgn0041096, rols, rolling pebbles, [Score=84.7, Expect=3e-16]} {Celegans: WBGene00006490, kdin-1, KiDINs220 (Vertebrate scaffold protein) homolog, [Score=59.7, Expect=1e-08]} {Smed: dd_Smed_v6_6779_0_1, dd_Smed_v6_6779_0_1, [Score=60.8, Expect=4e-09]} {RNA1509_27730} {RNA1310_4721} {RNA815_5358.1}
72. MligTC455_33845 53 1.1 Mlig455_004238

Neo: -

Age: -

0.959 - - - - 0.959 - Mlig455_004238 {REF} {Length: 727} {NoTransDecoderORF} {RNA1310_127880.2} {RNA815_42471}
73. MligTC455_25113 762 15.87 Mlig455_020768

Neo: -

Age: Down-Up-Down

Region-enriched R7: 2.653/0.00004
Region-enriched R2: 2.201/0.02449

0.958 - - - - 0.958 - Mlig455_020768 {REF} {Length: 810} {Celegans: WBGene00003748, nlp-10, Neuropeptide-Like Protein, [Score=46.2, Expect=1e-06]} {RNA1509_36958} {RNA1310_50245} {RNA815_48543}
74. MligTC455_19298 52 1.08 Mlig455_007404

Neo: -

Age: -

IRX4 0.957 - - - - 0.957 - Mlig455_007404 {REF} {Length: 1775} {Pfam: Homeobox KN domain [PF05920.13, score=53.9]; Homeodomain [PF00046.31, score=30.1]} {Human: ENSG00000113430, IRX4, iroquois homeobox 4, [RH, Score=149, Expect=2e-39]; ENSG00000159387, IRX6, iroquois homeobox 6, [RH, Score=147, Expect=6e-39]} {Mouse: ENSMUSG00000021604, Irx4, Iroquois homeobox 4, [RH, Score=150, Expect=5e-40]; ENSMUSG00000031738, Irx6, Iroquois homeobox 6, [RH, Score=145, Expect=1e-38]} {Dmel: FBgn0015919, caup, caupolican, [RH, Score=153, Expect=3e-40]} {Celegans: WBGene00007984, irx-1, Putative iroquois-class homeodomain protein irx-1, [RH, Score=124, Expect=1e-31]} {Smed: dd_Smed_v6_17352_0_1, dd_Smed_v6_17352_0_1, [RH, Score=159, Expect=3e-44]} {RNA1310_58105} {RNA815_61910}
75. MligTC455_51429 110 2.29 Mlig455_024820, Mlig455_024899

Neo: -

Age: Up-Down-Down

KCNK18 0.957 - - - 0.957 - -

Mlig455_024820 {REF} {Length: 2654} {Pfam: Ion channel [PF07885.18, score=117.7]; Ion transport protein [PF00520.33, score=25.7]} {Human: ENSG00000186795, KCNK18, potassium two pore domain channel subfamily K member 18, [RH, Score=102, Expect=6e-23]} {Mouse: ENSMUSG00000040901, Kcnk18, potassium channel, subfamily K, member 18, [Score=101, Expect=7e-23]; ENSMUSG00000033854, Kcnk10, potassium channel, subfamily K, member 10, [Score=97.8, Expect=3e-21]} {Dmel: FBgn0033257, sand, sandman, [RH, Score=159, Expect=1e-43]} {Celegans: WBGene00010784, twk-48, TWiK family of potassium channels, [Score=171, Expect=4e-48]} {Smed: dd_Smed_v6_19825_0_1, dd_Smed_v6_19825_0_1, [RH, Score=333, Expect=5e-110]} {RNA1509_56216} {RNA1310_14699.1, RNA1509_56216} {RNA1509_56216, RNA815_23055}

Mlig455_024899 {REF} {Length: 3465} {Pfam: Ion channel [PF07885.18, score=115.6]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=113.8]; Ion transport protein [PF00520.33, score=23.7]} {Human: ENSG00000186795, KCNK18, potassium two pore domain channel subfamily K member 18, [RH, Score=101, Expect=2e-22]} {Mouse: ENSMUSG00000040901, Kcnk18, potassium channel, subfamily K, member 18, [Score=101, Expect=2e-22]; ENSMUSG00000033854, Kcnk10, potassium channel, subfamily K, member 10, [Score=97.4, Expect=1e-20]} {Dmel: FBgn0033257, sand, sandman, [RH, Score=159, Expect=3e-42]} {Celegans: WBGene00010784, twk-48, TWiK family of potassium channels, [Score=170, Expect=2e-46]} {Smed: dd_Smed_v6_19825_0_1, dd_Smed_v6_19825_0_1, [RH, Score=333, Expect=3e-106]} {RNA1509_56216} {RNA1310_14699.1} {RNA815_252.1}
76. MligTC455_31455 858 17.87 Mlig455_032443

Neo: -

Age: -

0.955 - - - - 0.955 - Mlig455_032443 {REF} {Length: 696} {NoTransDecoderORF} {RNA1509_6069} {RNA1310_1086} {RNA815_8413.1}
77. MligTC455_45537 189 3.94 Mlig455_060669

Neo: -

Age: Up-Down-Up

NPR1 0.955 - - - 0.955 - - Mlig455_060669 {REF} {Length: 2668} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=200.8]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=56.3]; Protein kinase domain [PF00069.27, score=41.4]} {Human: ENSG00000169418, NPR1, natriuretic peptide receptor 1, [Score=382, Expect=4e-123]; ENSG00000159899, NPR2, natriuretic peptide receptor 2, [Score=375, Expect=9e-121]} {Mouse: ENSMUSG00000027931, Npr1, natriuretic peptide receptor 1, [Score=394, Expect=7e-128]; ENSMUSG00000028469, Npr2, natriuretic peptide receptor 2, [Score=377, Expect=9e-126]} {Dmel: FBgn0051183, CG31183, [Score=374, Expect=8e-118]} {Celegans: WBGene00020131, gcy-28, Receptor-type guanylate cyclase gcy-28, [Score=348, Expect=1e-109]} {Smed: dd_Smed_v6_14331_0_1, dd_Smed_v6_14331_0_1, [Score=429, Expect=4e-141]} {RNA1509_50551} {RNA1310_4016.1} {RNA815_2101.1}
78. MligTC455_32422 37 0.78 Mlig455_031348

Neo: -

Age: -

CHRNA6 0.953 - - - - 0.953 - Mlig455_031348 {REF} {Length: 1659} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=69.7]} {Human: ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=61.6, Expect=5e-10]; ENSG00000160716, CHRNB2, cholinergic receptor nicotinic beta 2 subunit, [Score=61.2, Expect=8e-10]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=61.2, Expect=5e-10]; ENSMUSG00000027950, Chrnb2, cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal), [Score=60.8, Expect=8e-10]; ENSMUSG00000055026, Gabrg3, gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3, [Score=58.5, Expect=4e-09]} {Dmel: FBgn0000038, nAChRbeta1, nicotinic Acetylcholine Receptor beta1, [Score=48.5, Expect=4e-06]} {Celegans: WBGene00000057, acr-18, AcetylCholine Receptor; Acetylcholine receptor, one of nine alpha a7-like nicotinic acetylcholine receptor subunits (58.6 kD) (Acr-18), [Score=63.5, Expect=5e-11]} {Smed: dd_Smed_v6_30253_0_1, dd_Smed_v6_30253_0_1, [Score=59.3, Expect=6e-10]} {RNA1310_61084} {RNA815_48984}
79. MligTC455_07996 46 0.95 Mlig455_004474, Mlig455_037367

Neo: -

Age: -

NPFFR2 0.952 - - - 0.952 - -

Mlig455_004474 {REF} {Length: 1579} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=157.8]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=39.7]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=30.7]; Serpentine type 7TM GPCR chemoreceptor Srv [PF10323.11, score=29.9]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=28.6]; Olfactory receptor [PF13853.8, score=18.9]} {Human: ENSG00000056291, NPFFR2, neuropeptide FF receptor 2, [Score=111, Expect=1e-26]; ENSG00000174417, TRHR, thyrotropin releasing hormone receptor, [Score=110, Expect=2e-26]; ENSG00000182687, GALR2, galanin receptor 2, [Score=107, Expect=3e-25]; ENSG00000139874, SSTR1, somatostatin receptor 1, [Score=107, Expect=3e-25]} {Mouse: ENSMUSG00000038760, Trhr, thyrotropin releasing hormone receptor, [Score=112, Expect=2e-27]; ENSMUSG00000037014, Sstr4, somatostatin receptor 4, [Score=111, Expect=7e-27]; ENSMUSG00000020793, Galr2, galanin receptor 2, [Score=110, Expect=1e-26]; ENSMUSG00000035431, Sstr1, somatostatin receptor 1, [Score=107, Expect=1e-25]} {Dmel: FBgn0004841, TkR86C, Tachykinin-like receptor at 86C, [Score=120, Expect=8e-30]} {Celegans: WBGene00022004, npr-22, NeuroPeptide Receptor family, [Score=108, Expect=6e-26]} {Smed: dd_Smed_v6_22653_0_1, dd_Smed_v6_22653_0_1, [RH, Score=231, Expect=3e-72]} {RNA1310_68544} {RNA815_44146}

Mlig455_037367 {REF} {Length: 1622} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=157.8]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=39.7]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=30.7]; Serpentine type 7TM GPCR chemoreceptor Srv [PF10323.11, score=29.9]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=28.6]; Olfactory receptor [PF13853.8, score=18.9]} {Human: ENSG00000056291, NPFFR2, neuropeptide FF receptor 2, [Score=111, Expect=1e-26]; ENSG00000174417, TRHR, thyrotropin releasing hormone receptor, [Score=110, Expect=2e-26]; ENSG00000182687, GALR2, galanin receptor 2, [Score=107, Expect=3e-25]; ENSG00000139874, SSTR1, somatostatin receptor 1, [Score=107, Expect=3e-25]} {Mouse: ENSMUSG00000038760, Trhr, thyrotropin releasing hormone receptor, [Score=112, Expect=2e-27]; ENSMUSG00000037014, Sstr4, somatostatin receptor 4, [Score=111, Expect=7e-27]; ENSMUSG00000020793, Galr2, galanin receptor 2, [Score=110, Expect=1e-26]; ENSMUSG00000035431, Sstr1, somatostatin receptor 1, [Score=107, Expect=1e-25]} {Dmel: FBgn0004841, TkR86C, Tachykinin-like receptor at 86C, [Score=120, Expect=8e-30]} {Celegans: WBGene00022004, npr-22, NeuroPeptide Receptor family, [Score=108, Expect=6e-26]} {Smed: dd_Smed_v6_22653_0_1, dd_Smed_v6_22653_0_1, [RH, Score=231, Expect=3e-72]} {RNA1310_68544} {RNA815_44146}
80. MligTC455_46528 2412 50.26 Mlig455_050051, Mlig455_050067, Mlig455_050098

Neo: -

Age: logFC(26M/2M)=-0.382

0.952 - - - - - 0.952

Mlig455_050051 {REF} {Length: 2636} {Pfam: Wnt and FGF inhibitory regulator [PF13908.8, score=26.7]; Lectin C-type domain [PF00059.23, score=23.5]} {RNA1509_3972} {RNA1310_6232} {RNA815_6166}

Mlig455_050067 {REF} {Length: 3307} {Pfam: Wnt and FGF inhibitory regulator [PF13908.8, score=26.7]; Lectin C-type domain [PF00059.23, score=23.5]} {RNA1509_17734, RNA1509_36705, RNA1509_3972, RNA1509_49764} {RNA1310_6232, RNA1509_17734, RNA1509_36705, RNA1509_49764} {RNA1509_17734, RNA1509_36705, RNA1509_49764, RNA815_6166}

Mlig455_050098 {REF} {Length: 3005} {Pfam: Wnt and FGF inhibitory regulator [PF13908.8, score=26.5]; Lectin C-type domain [PF00059.23, score=20.5]} {RNA1509_3972} {RNA1310_6232, RNA1509_3972} {RNA1509_3972, RNA815_6166}
81. MligTC455_47311 16 0.33 Mlig455_045815

Neo: -

Age: -

Region-enriched R4: 2.374/0.01691

KREMEN2 0.952 - - - 0.952 - - Mlig455_045815 {REF} {Length: 1747} {Pfam: WSC domain [PF01822.21, score=57.3]} {Human: ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=58.5, Expect=2e-09]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=58.2, Expect=3e-09]; ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=55.5, Expect=2e-08]} {RNA1509_46373} {RNA1310_44003} {RNA815_48857}

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