Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_35747 | 14 | 0.30 | Mlig455_044386 | Neo: - Age: Down-Up-Down |
HTR3A | Mlig455_044386 {REF} {Length: 1966} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=73.0]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=37.0]} {Human: ENSG00000166736, HTR3A, 5-hydroxytryptamine receptor 3A, [Score=94.7, Expect=1e-20]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=94.4, Expect=1e-20]; ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=90.1, Expect=2e-19]} {Mouse: ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=95.1, Expect=4e-21]; ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=94.4, Expect=6e-21]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=105, Expect=1e-24]} {Celegans: WBGene00001133, eat-2, Neuronal acetylcholine receptor subunit eat-2, [Score=104, Expect=2e-24]} {Smed: dd_Smed_v6_18184_0_1, dd_Smed_v6_18184_0_1, [Score=98.2, Expect=2e-22]} {RNA1310_56011} {RNA815_22778} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -2.584 | 0.733 | 0.99926 | 1.00000 | |
RegionR2 | 3.247 | 0.733 | 0.39480 | 0.78901 | |
RegionR3 | 1.427 | 0.733 | 0.82474 | 1.00000 | |
RegionR4 | 0.76 | 0.733 | 0.80890 | 1.00000 | |
RegionR5 | 0.383 | 0.733 | 0.99366 | 1.00000 | |
RegionR6 | -1.166 | 0.733 | 0.99961 | 1.00000 | |
RegionR7 | -1.042 | 0.733 | 0.99991 | 1.00000 | |
RegionR8 | -1.025 | 0.733 | 0.99974 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -0.164 | 0.733 | 0.99987 | 1.00000 | |
RegenerationR2 | -1.319 | 0.733 | 0.14439 | 0.57591 | |
RegenerationR3 | -2.52 | 0.733 | 0.10717 | 0.51730 | |
RegenerationR4 | -1.92 | 0.733 | 0.18500 | 0.62629 | |
RegenerationR5 | -1.888 | 0.733 | 0.14066 | 0.55365 | |
RegenerationR6 | -0.571 | 0.733 | 0.99978 | 1.00000 | |
RegenerationBL | -1.112 | 0.733 | 0.99964 | 1.00000 | |
RegenerationTP | 2.036 | 0.733 | 0.96977 | 1.00000 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_35747 | 14 | 0.3 | Mlig455_044386 | Neo: - Age: Down-Up-Down |
HTR3A | 2 | - | - | 1.000 | - | 1.000 | - | Mlig455_044386 {REF} {Length: 1966} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=73.0]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=37.0]} {Human: ENSG00000166736, HTR3A, 5-hydroxytryptamine receptor 3A, [Score=94.7, Expect=1e-20]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=94.4, Expect=1e-20]; ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=90.1, Expect=2e-19]} {Mouse: ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=95.1, Expect=4e-21]; ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=94.4, Expect=6e-21]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=105, Expect=1e-24]} {Celegans: WBGene00001133, eat-2, Neuronal acetylcholine receptor subunit eat-2, [Score=104, Expect=2e-24]} {Smed: dd_Smed_v6_18184_0_1, dd_Smed_v6_18184_0_1, [Score=98.2, Expect=2e-22]} {RNA1310_56011} {RNA815_22778} |
2. | MligTC455_50617 | 99 | 2.07 | Mlig455_043350 | Neo: - Age: Down-Down-Up |
1.708 | - | - | 0.950 | - | 0.758 | - | Mlig455_043350 {REF} {Length: 881} {RNA1310_47300.1} {RNA815_35912} | |
3. | MligTC455_16749 | 454 | 9.45 | Mlig455_001550, Mlig455_046548 | Neo: - Age: logFC(26M/2M)=0.515 Region-specific R2: 4.360 Region-enriched R2: 3.409/0.00015 |
TRAF4 | 0.985 | - | - | - | - | 0.985 | - | Mlig455_001550 {REF} {Length: 4563} {Pfam: TRAF-type zinc finger [PF02176.20, score=81.2]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=27.3]; Seven in absentia protein family [PF03145.18, score=27.2]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=23.0]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=22.9]; zinc finger of C3HC4-type, RING [PF15227.8, score=20.4]; zf-RING of BARD1-type protein [PF14835.8, score=20.3]; Ring finger domain [PF13639.8, score=19.5]} {Human: ENSG00000076604, TRAF4, TNF receptor associated factor 4, [Score=237, Expect=4e-72]} {Mouse: ENSMUSG00000017386, Traf4, TNF receptor associated factor 4, [Score=241, Expect=7e-74]} {Dmel: FBgn0026319, Traf4, TNF-receptor-associated factor 4, [Score=164, Expect=1e-44]} {Celegans: WBGene00006612, trf-1, TNF Receptor Associated Factor (TRAF) homolog; TRF-1, [RH, Score=276, Expect=1e-87]} {Smed: dd_Smed_v6_13517_0_1, dd_Smed_v6_13517_0_1, [RH, Score=592, Expect=0.0]} {RNA1509_20900} {RNA1310_14813, RNA1509_20900} {RNA1509_20900, RNA815_2335.1} Mlig455_046548 {REF} {Length: 3881} {Pfam: TRAF-type zinc finger [PF02176.20, score=81.2]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=27.3]; Seven in absentia protein family [PF03145.18, score=27.2]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=23.0]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=22.9]; zinc finger of C3HC4-type, RING [PF15227.8, score=20.4]; zf-RING of BARD1-type protein [PF14835.8, score=20.3]; Ring finger domain [PF13639.8, score=19.5]} {Human: ENSG00000076604, TRAF4, TNF receptor associated factor 4, [Score=236, Expect=1e-71]} {Mouse: ENSMUSG00000017386, Traf4, TNF receptor associated factor 4, [Score=240, Expect=3e-73]} {Dmel: FBgn0026319, Traf4, TNF-receptor-associated factor 4, [Score=164, Expect=9e-45]} {Celegans: WBGene00006612, trf-1, TNF Receptor Associated Factor (TRAF) homolog; TRF-1, [RH, Score=275, Expect=6e-87]} {Smed: dd_Smed_v6_13517_0_1, dd_Smed_v6_13517_0_1, [RH, Score=592, Expect=0.0]} {RNA1509_20900} {RNA1310_14813} {RNA815_2335.1} |
4. | MligTC455_57177 | 11 | 0.24 | Mlig455_001352 | Neo: - Age: - |
0.984 | - | - | - | - | 0.984 | - | Mlig455_001352 {REF} {Length: 533} {Pfam: zinc-binding in reverse transcriptase [PF13966.8, score=23.3]} {RNA1310_41519} | |
5. | MligTC455_39296 | 144 | 2.99 | Mlig455_011714, Mlig455_026830, Mlig455_038021, Mlig455_057425 | Neo: Germline Age: Up-Down-Down Region-enriched R2: 4.786/0.04939 |
0.975 | - | - | - | - | 0.975 | - | Mlig455_011714 {REF} {Length: 3110} {Pfam: Transposase protein [PF12017.10, score=74.1]; THAP domain [PF05485.14, score=36.7]} {RNA1509_56557} {RNA1310_11302, RNA1509_56557} {RNA1509_56557, RNA815_17021} Mlig455_026830 {REF} {Length: 1916} {Pfam: Transposase protein [PF12017.10, score=43.7]} {RNA1509_56557} {RNA1310_48290} {RNA815_17021} Mlig455_038021 {REF} {Length: 3107} {Pfam: Transposase protein [PF12017.10, score=73.7]; THAP domain [PF05485.14, score=35.9]} {RNA1509_56557} {RNA1310_11302} {RNA815_17021} Mlig455_057425 {REF} {Length: 3527} {Pfam: Transposase protein [PF12017.10, score=66.6]; THAP domain [PF05485.14, score=35.4]} {RNA1509_56557} {RNA1310_11302} {RNA815_17021} |
|
6. | MligTC455_45918 | 280 | 5.83 | Mlig455_040163 | Neo: - Age: Up-Down-Up Region-enriched R8: 3.045/0.00855 |
PLSCR1 | 0.974 | - | - | - | - | 0.974 | - | Mlig455_040163 {REF} {Length: 4635} {Pfam: Scramblase [PF03803.17, score=246.2]; Zinc-finger double domain [PF13465.8, score=22.5]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=244, Expect=2e-73]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=238, Expect=4e-71]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=237, Expect=6e-71]} {Dmel: FBgn0052056, scramb1, scramblase 1, [RH, Score=248, Expect=8e-74]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=197, Expect=4e-57]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [RH, Score=307, Expect=2e-97]} {RNA1509_29261} {RNA1310_13155} {RNA815_8732} |
7. | MligTC455_18500 | 1471 | 30.65 | Mlig455_031869 | Neo: - Age: Down-Up-Down, logFC(26M/2M)=-0.532 Region-enriched R2: 1.314/0.00526 Regeneration-downregulated BL: -2.252 Regeneration-depleted BL: -2.252 |
0.973 | - | - | - | - | 0.973 | - | Mlig455_031869 {REF} {Length: 3516} {RNA1509_12038, RNA1509_15832, RNA1509_26696, RNA1509_30104, RNA1509_49054} {RNA1310_23818, RNA1509_12038, RNA1509_15832, RNA1509_26696, RNA1509_30104, RNA1509_49054} {RNA1509_12038, RNA1509_15832, RNA1509_26696, RNA1509_30104, RNA1509_49054, RNA815_15169} | |
8. | MligTC455_42087 | 129 | 2.68 | Mlig455_028171 | Neo: - Age: - |
0.972 | - | - | - | - | 0.972 | - | Mlig455_028171 {REF} {Length: 2511} {RNA1509_40406} {RNA1310_12938} {RNA815_16887} | |
9. | MligTC455_47538 | 50 | 1.03 | Mlig455_025826 | Neo: - Age: - Region-enriched R2: 5.073/0.01138 |
CALM2 | 0.972 | - | - | - | - | 0.972 | - | Mlig455_025826 {REF} {Length: 1670} {Pfam: EF hand [PF00036.34, score=107.9]; EF-hand domain pair [PF13499.8, score=105.5]; EF hand [PF13202.8, score=83.6]; EF-hand domain pair [PF13833.8, score=83.3]; EF-hand domain [PF13405.8, score=75.8]; EF-hand domain [PF14658.8, score=35.5]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=29.8]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=27.8]; Dockerin type I domain [PF00404.20, score=20.3]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=93.2, Expect=3e-24]; ENSG00000198668, CALM1, calmodulin 1, [Score=93.2, Expect=3e-24]; ENSG00000160014, CALM3, calmodulin 3, [Score=93.2, Expect=3e-24]; ENSG00000178363, CALML3, calmodulin like 3, [Score=92.8, Expect=4e-24]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=99.8, Expect=5e-27]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=91.3, Expect=6e-24]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=90.9, Expect=9e-24]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=90.9, Expect=7e-24]} {RNA1509_52504} {RNA1310_7529} {RNA815_34450} |
10. | MligTC455_42029 | 61 | 1.28 | Mlig455_020044 | Neo: - Age: - |
HMGCLL1 | 0.971 | - | - | - | - | 0.971 | - | Mlig455_020044 {REF} {Length: 2499} {TRANSSPLICED} {Pfam: HMGL-like [PF00682.21, score=166.2]} {Human: ENSG00000146151, HMGCLL1, 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1, [RH, Score=325, Expect=3e-110]; ENSG00000117305, HMGCL, 3-hydroxy-3-methylglutaryl-CoA lyase, [RH, Score=324, Expect=4e-110]} {Mouse: ENSMUSG00000028672, Hmgcl, 3-hydroxy-3-methylglutaryl-Coenzyme A lyase, [RH, Score=332, Expect=3e-113]; ENSMUSG00000007908, Hmgcll1, 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like 1, [RH, Score=327, Expect=4e-111]} {Dmel: FBgn0031877, CG10399, [RH, Score=318, Expect=4e-108]} {Celegans: WBGene00022150, Y71G12B.10, [RH, Score=271, Expect=9e-90]} {Smed: dd_Smed_v6_5547_0_1, dd_Smed_v6_5547_0_1, [RH, Score=287, Expect=2e-96]} {RNA1509_48953, RNA1509_54566} {RNA1310_3243, RNA1509_48953, RNA1509_54566} {RNA1509_48953, RNA1509_54566, RNA815_27742} |
11. | MligTC455_09706 | 30 | 0.62 | Mlig455_015819 | Neo: - Age: - |
0.966 | - | - | - | - | 0.966 | - | Mlig455_015819 {REF} {Length: 776} {NoTransDecoderORF} {RNA1509_15725} {RNA1310_15694.2} {RNA815_48933} | |
12. | MligTC455_25865 | 96 | 2 | Mlig455_008643, Mlig455_069411 | Neo: - Age: - Region-enriched R2: 7.383/0.00023 |
SETMAR | 0.961 | - | - | - | - | 0.961 | - | Mlig455_008643 {REF} {Length: 1815} {Pfam: Transposase (partial DDE domain) [PF01359.20, score=48.0]; HTH domain in Mos1 transposase [PF17906.3, score=34.1]; Homeodomain-like domain [PF13565.8, score=28.7]; Transposase [PF01498.20, score=21.5]; Winged helix-turn-helix DNA-binding [PF13412.8, score=20.0]; AsnC-type helix-turn-helix domain [PF13404.8, score=19.2]; Winged helix-turn helix [PF13551.8, score=18.7]} {Human: ENSG00000170364, SETMAR, SET domain and mariner transposase fusion gene, [Score=135, Expect=7e-35]} {Smed: dd_Smed_v6_16659_0_1, dd_Smed_v6_16659_0_1, [RH, Score=50.1, Expect=1e-07]} {RNA1509_35414} {RNA1310_3855.1} {RNA815_19895} Mlig455_069411 {REF} {Length: 1815} {Pfam: Transposase (partial DDE domain) [PF01359.20, score=47.9]; HTH domain in Mos1 transposase [PF17906.3, score=34.2]; Homeodomain-like domain [PF13565.8, score=28.7]; Transposase [PF01498.20, score=21.5]; Winged helix-turn-helix DNA-binding [PF13412.8, score=20.0]; AsnC-type helix-turn-helix domain [PF13404.8, score=19.2]; Winged helix-turn helix [PF13551.8, score=18.7]} {Human: ENSG00000170364, SETMAR, SET domain and mariner transposase fusion gene, [Score=135, Expect=9e-35]} {Smed: dd_Smed_v6_16659_0_1, dd_Smed_v6_16659_0_1, [RH, Score=50.1, Expect=1e-07]} {RNA1509_35414} {RNA1310_3855.1} {RNA815_19895} |
13. | MligTC455_34010 | 204 | 4.26 | Mlig455_024028, Mlig455_024093 | Neo: - Age: Up-Down-Down |
KCNC1 | 0.959 | - | - | - | - | 0.959 | - | Mlig455_024028 {REF} {Length: 3896} {Pfam: Ion transport protein [PF00520.33, score=148.2]; BTB/POZ domain [PF02214.24, score=101.1]; Ion channel [PF07885.18, score=44.0]} {Human: ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [RH, Score=426, Expect=1e-141]; ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [RH, Score=424, Expect=2e-140]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [RH, Score=407, Expect=1e-133]} {Mouse: ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [RH, Score=426, Expect=5e-142]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [RH, Score=411, Expect=2e-135]; ENSMUSG00000062785, Kcnc3, potassium voltage gated channel, Shaw-related subfamily, member 3, [RH, Score=408, Expect=1e-132]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [RH, Score=710, Expect=0.0]} {Celegans: WBGene00004793, shw-3, SHaW family of potassium channels; Voltage-gated K+ channel isoform 1, [RH, Score=590, Expect=0.0]} {Smed: dd_Smed_v6_9740_0_1, dd_Smed_v6_9740_0_1, [RH, Score=689, Expect=0.0]} {RNA1509_54375} {RNA1310_15083.2} {RNA815_13734} Mlig455_024093 {REF} {Length: 3992} {Pfam: Ion transport protein [PF00520.33, score=148.2]; BTB/POZ domain [PF02214.24, score=101.1]; Ion channel [PF07885.18, score=44.0]} {Human: ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [RH, Score=426, Expect=1e-141]; ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [RH, Score=424, Expect=2e-140]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [RH, Score=407, Expect=1e-133]} {Mouse: ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [RH, Score=426, Expect=5e-142]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [RH, Score=411, Expect=2e-135]; ENSMUSG00000062785, Kcnc3, potassium voltage gated channel, Shaw-related subfamily, member 3, [RH, Score=408, Expect=1e-132]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [RH, Score=710, Expect=0.0]} {Celegans: WBGene00004793, shw-3, SHaW family of potassium channels; Voltage-gated K+ channel isoform 1, [RH, Score=590, Expect=0.0]} {Smed: dd_Smed_v6_9740_0_1, dd_Smed_v6_9740_0_1, [RH, Score=689, Expect=0.0]} {RNA1509_54375} {RNA1310_15083.2} {RNA815_13734} |
14. | MligTC455_41910 | 46 | 0.96 | Mlig455_031932, Mlig455_032665, Mlig455_070395 | Neo: - Age: - |
0.959 | - | - | 0.959 | - | - | - | Mlig455_031932 {REF} {Length: 811} {Pfam: PAN-like domain [PF08277.14, score=21.2]; Carbohydrate binding domain (family 19) [PF03427.15, score=18.8]} {RNA1310_52317.2} {RNA815_34259} Mlig455_032665 {REF} {Length: 903} {Pfam: Carbohydrate binding domain (family 19) [PF03427.15, score=21.5]} {RNA1310_52317.1} {RNA815_34259} Mlig455_070395 {REF} {Length: 636} {Pfam: Carbohydrate binding domain (family 19) [PF03427.15, score=21.5]} {RNA1310_52317.1} {RNA815_34259} |
|
15. | MligTC455_38490 | 38 | 0.8 | Mlig455_028980 | Neo: - Age: Down-Up-Down |
0.957 | - | - | - | - | 0.957 | - | Mlig455_028980 {REF} {Length: 3387} {RNA1509_29504} {RNA1310_1629} {RNA815_5687} | |
16. | MligTC455_02518 | 180 | 3.75 | Mlig455_055401 | Neo: - Age: - |
0.955 | - | - | 0.955 | - | - | - | Mlig455_055401 {REF} {Length: 2759} {RNA1509_29842} {RNA1310_25832} {RNA815_24592} | |
17. | MligTC455_28446 | 134 | 2.79 | Mlig455_061706 | Neo: - Age: - |
0.955 | - | - | - | - | 0.955 | - | Mlig455_061706 {REF} {Length: 1760} {NoTransDecoderORF} {RNA1509_12781} {RNA1310_63.1} {RNA815_23.1} | |
18. | MligTC455_15492 | 69 | 1.44 | Mlig455_022488 | Neo: - Age: Down-Up-Up |
0.952 | - | - | - | - | 0.952 | - | Mlig455_022488 {REF} {Length: 1351} {RNA1310_26051} {RNA815_10966} |