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Results for MligTC455_36362

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_36362 266 5.55 Mlig455_029693, Mlig455_034838

Neo: -

Age: -

 TLCD1

Mlig455_029693 {REF} {Length: 2356} {Pfam: TLC domain [PF03798.18, score=71.5]} {Human: ENSG00000160606, TLCD1, TLC domain containing 1, [RH, Score=93.2, Expect=6e-22]} {Mouse: ENSMUSG00000019437, Tlcd1, TLC domain containing 1, [RH, Score=94.4, Expect=1e-22]} {Celegans: WBGene00013407, Y63D3A.8, [RH, Score=100, Expect=2e-24]} {Smed: dd_Smed_v6_6951_0_2, dd_Smed_v6_6951_0_2, [Score=237, Expect=1e-77]} {RNA1509_18403} {RNA1310_26765} {RNA815_14967}

Mlig455_034838 {REF} {Length: 4633} {Pfam: TLC domain [PF03798.18, score=71.6]} {Human: ENSG00000160606, TLCD1, TLC domain containing 1, [RH, Score=92.4, Expect=1e-21]} {Mouse: ENSMUSG00000019437, Tlcd1, TLC domain containing 1, [RH, Score=93.6, Expect=3e-22]} {Celegans: WBGene00013407, Y63D3A.8, [RH, Score=101, Expect=7e-25]} {Smed: dd_Smed_v6_6951_0_2, dd_Smed_v6_6951_0_2, [Score=236, Expect=4e-77]} {RNA1509_18403} {RNA1310_7362.1} {RNA815_6705.1}

Cumulative graph for MligTC455_36362

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 2.075 2.873 0.09872 0.66418
RegionR2 0.254 2.873 0.68972 1.00000
RegionR3 -0.58 2.873 0.22325 0.76473
RegionR4 -0.256 2.873 0.70006 0.98889
RegionR5 -1.256 2.873 0.00497 0.03447
RegionR6 -0.652 2.873 0.18966 0.75566
RegionR7 -0.206 2.873 0.76038 1.00000
RegionR8 0.622 2.873 0.40701 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -7.242 2.873 0.08099 0.77668
RegenerationR2 0.219 2.873 0.64768 0.93520
RegenerationR3 0.479 2.873 0.41785 0.81356
RegenerationR4 -0.814 2.873 0.20921 0.65687
RegenerationR5 0.006 2.873 0.99690 1.00000
RegenerationR6 0.069 2.873 0.90956 1.00000
RegenerationBL -1.553 2.873 0.12072 0.41222
RegenerationTP -1.842 2.873 0.04816 0.36079


Genes with expression patterns similar to MligTC455_36362

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_36362 266 5.55 Mlig455_029693, Mlig455_034838

Neo: -

Age: -

 TLCD1 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_029693 {REF} {Length: 2356} {Pfam: TLC domain [PF03798.18, score=71.5]} {Human: ENSG00000160606, TLCD1, TLC domain containing 1, [RH, Score=93.2, Expect=6e-22]} {Mouse: ENSMUSG00000019437, Tlcd1, TLC domain containing 1, [RH, Score=94.4, Expect=1e-22]} {Celegans: WBGene00013407, Y63D3A.8, [RH, Score=100, Expect=2e-24]} {Smed: dd_Smed_v6_6951_0_2, dd_Smed_v6_6951_0_2, [Score=237, Expect=1e-77]} {RNA1509_18403} {RNA1310_26765} {RNA815_14967}

Mlig455_034838 {REF} {Length: 4633} {Pfam: TLC domain [PF03798.18, score=71.6]} {Human: ENSG00000160606, TLCD1, TLC domain containing 1, [RH, Score=92.4, Expect=1e-21]} {Mouse: ENSMUSG00000019437, Tlcd1, TLC domain containing 1, [RH, Score=93.6, Expect=3e-22]} {Celegans: WBGene00013407, Y63D3A.8, [RH, Score=101, Expect=7e-25]} {Smed: dd_Smed_v6_6951_0_2, dd_Smed_v6_6951_0_2, [Score=236, Expect=4e-77]} {RNA1509_18403} {RNA1310_7362.1} {RNA815_6705.1}
2. MligTC455_32088 109 2.28 Mlig455_054671

Neo: -

Age: -

 2.619 - - 0.953 0.881 - 0.785 Mlig455_054671 {REF} {Length: 2191} {RNA1509_42275} {RNA1310_5257.2} {RNA815_4711}
3. MligTC455_18114 414 8.63 Mlig455_038324, Mlig455_050230

Neo: -

Age: Down-Up-Down

 2.618 - - 0.964 0.867 - 0.787

Mlig455_038324 {REF} {Length: 2163} {Pfam: Transmembrane protein family 72 [PF16054.7, score=60.9]} {Smed: dd_Smed_v6_6789_0_1, dd_Smed_v6_6789_0_1, [RH, Score=94.7, Expect=4e-24]} {RNA1509_37575} {RNA1310_23999} {RNA815_9176.1}

Mlig455_050230 {REF} {Length: 2326} {Pfam: Transmembrane protein family 72 [PF16054.7, score=60.9]} {Smed: dd_Smed_v6_6789_0_1, dd_Smed_v6_6789_0_1, [RH, Score=94.7, Expect=4e-24]} {RNA1509_37575} {RNA1310_23999, RNA1509_37575} {RNA1509_37575, RNA815_26984}
4. MligTC455_38355 110 2.29 Mlig455_039715, Mlig455_039769

Neo: -

Age: -

 KCNB2 2.6 - - 0.969 0.789 0.842 -

Mlig455_039715 {REF} {Length: 3883} {Pfam: Ion transport protein [PF00520.33, score=114.4]; BTB/POZ domain [PF02214.24, score=75.0]; Ion channel [PF07885.18, score=43.6]} {Human: ENSG00000182674, KCNB2, potassium voltage-gated channel subfamily B member 2, [Score=218, Expect=3e-60]; ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [Score=213, Expect=2e-60]; ENSG00000158445, KCNB1, potassium voltage-gated channel subfamily B member 1, [Score=213, Expect=7e-59]; ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=210, Expect=2e-59]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [Score=209, Expect=7e-59]} {Mouse: ENSMUSG00000092083, Kcnb2, potassium voltage gated channel, Shab-related subfamily, member 2, [Score=219, Expect=5e-61]; ENSMUSG00000050556, Kcnb1, potassium voltage gated channel, Shab-related subfamily, member 1, [Score=218, Expect=1e-60]; ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [Score=214, Expect=8e-61]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=213, Expect=6e-60]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=230, Expect=8e-67]} {Celegans: WBGene00008819, shw-1, SHaW family of potassium channels, [Score=236, Expect=3e-69]} {Smed: dd_Smed_v6_11886_0_1, dd_Smed_v6_11886_0_1, [RH, Score=592, Expect=0.0]} {RNA1509_22940} {RNA1310_17926} {RNA815_8687.1}

Mlig455_039769 {REF} {Length: 4176} {Pfam: Ion transport protein [PF00520.33, score=116.7]; BTB/POZ domain [PF02214.24, score=75.0]; Ion channel [PF07885.18, score=43.6]; Polycystin cation channel [PF08016.14, score=20.7]} {Human: ENSG00000182674, KCNB2, potassium voltage-gated channel subfamily B member 2, [Score=219, Expect=8e-61]; ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [Score=216, Expect=2e-61]; ENSG00000158445, KCNB1, potassium voltage-gated channel subfamily B member 1, [Score=215, Expect=2e-59]; ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=213, Expect=2e-60]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [Score=213, Expect=4e-60]; ENSG00000131398, KCNC3, potassium voltage-gated channel subfamily C member 3, [Score=210, Expect=4e-58]} {Mouse: ENSMUSG00000092083, Kcnb2, potassium voltage gated channel, Shab-related subfamily, member 2, [Score=221, Expect=2e-61]; ENSMUSG00000050556, Kcnb1, potassium voltage gated channel, Shab-related subfamily, member 1, [Score=219, Expect=4e-61]; ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [Score=216, Expect=6e-62]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=215, Expect=6e-61]; ENSMUSG00000062785, Kcnc3, potassium voltage gated channel, Shaw-related subfamily, member 3, [Score=211, Expect=1e-58]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=231, Expect=2e-67]} {Celegans: WBGene00008819, shw-1, SHaW family of potassium channels, [Score=239, Expect=2e-70]} {Smed: dd_Smed_v6_11886_0_1, dd_Smed_v6_11886_0_1, [RH, Score=595, Expect=0.0]} {RNA1509_22940} {RNA1310_17926} {RNA815_8687.1}
5. MligTC455_26356 62 1.3 Mlig455_042551

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.548

 GRIK2 2.6 - - 0.956 0.751 0.893 - Mlig455_042551 {REF} {Length: 2917} {Pfam: Ligand-gated ion channel [PF00060.28, score=82.2]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=60.7]; Receptor family ligand binding region [PF01094.30, score=32.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=27.3]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=144, Expect=9e-35]; ENSG00000152208, GRID2, glutamate ionotropic receptor delta type subunit 2, [Score=141, Expect=7e-34]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=143, Expect=1e-34]; ENSMUSG00000071424, Grid2, glutamate receptor, ionotropic, delta 2, [Score=142, Expect=2e-34]} {Dmel: FBgn0051201, GluRIIE, Glutamate receptor IIE, [Score=119, Expect=3e-27]} {Celegans: WBGene00001616, glr-5, GLutamate Receptor family (AMPA), [Score=123, Expect=2e-28]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=247, Expect=4e-74]} {RNA1310_21865} {RNA815_26044}
6. MligTC455_31805 747 15.56 Mlig455_070318

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.499

 EFCAB6 2.595 - - 0.966 - 0.834 0.795 Mlig455_070318 {REF} {Length: 3714} {Pfam: EF-hand domain pair [PF13499.8, score=82.4]; EF-hand domain [PF08976.13, score=72.0]; EF-hand domain pair [PF13833.8, score=64.0]; EF-hand domain [PF13405.8, score=56.9]; EF hand [PF00036.34, score=53.2]; EF-hand domain [PF14658.8, score=34.9]; Family of unknown function (DUF5580) [PF17743.3, score=27.9]; EF hand [PF13202.8, score=22.4]} {Human: ENSG00000186976, EFCAB6, EF-hand calcium binding domain 6, [Score=86.3, Expect=2e-16]} {Mouse: ENSMUSG00000022441, Efcab6, EF-hand calcium binding domain 6, [Score=76.6, Expect=1e-13]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=48.9, Expect=2e-06]} {Celegans: WBGene00017394, cal-8, CALmodulin related genes, [Score=50.8, Expect=4e-07]} {Smed: dd_Smed_v6_20435_0_1, dd_Smed_v6_20435_0_1, [Score=157, Expect=1e-40]} {RNA1509_7148} {RNA1310_3069.1} {RNA815_3758}
7. MligTC455_39463 228 4.76 Mlig455_025914, Mlig455_025946

Neo: -

Age: -

Regeneration-downregulated R4: -3.846

Regeneration-depleted R4: -3.846

 2.585 - - 0.961 0.771 0.853 -

Mlig455_025914 {REF} {Length: 1257} {RNA1310_37139.1} {RNA815_50944}

Mlig455_025946 {REF} {Length: 2808} {tRNA: Ala(CGC),pseudo, score=22.1} {Pfam: Lectin C-type domain [PF00059.23, score=35.2]} {Smed: dd_Smed_v6_84586_0_1, dd_Smed_v6_84586_0_1, [RH, Score=53.1, Expect=4e-09]} {RNA1509_4810} {RNA1310_37139.1} {RNA815_40603}
8. MligTC455_49957 119 2.47 Mlig455_005610, Mlig455_014448

Neo: -

Age: -

 2.575 - - 0.958 0.769 0.848 -

Mlig455_005610 {REF} {Length: 1455} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=66.2, Expect=4e-13]} {RNA1310_45206} {RNA815_28788}

Mlig455_014448 {REF} {Length: 1455} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=63.2, Expect=6e-12]} {RNA1310_45206} {RNA815_28788}
9. MligTC455_41430 65 1.35 Mlig455_070915

Neo: -

Age: -

 BHLHE22 2.561 - - 0.962 0.722 0.877 - Mlig455_070915 {REF} {Length: 1052} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=58.4]} {Human: ENSG00000180828, BHLHE22, basic helix-loop-helix family member e22, [RH, Score=135, Expect=4e-37]} {Mouse: ENSMUSG00000025128, Bhlhe22, basic helix-loop-helix family, member e22, [RH, Score=133, Expect=8e-37]; ENSMUSG00000045493, Bhlhe23, basic helix-loop-helix family, member e23, [RH, Score=129, Expect=1e-36]} {Dmel: FBgn0032651, Oli, Olig family, [RH, Score=135, Expect=4e-39]} {Celegans: WBGene00001961, hlh-17, Helix Loop Helix, [RH, Score=103, Expect=2e-28]} {Smed: dd_Smed_v6_12722_0_1, dd_Smed_v6_12722_0_1, [RH, Score=129, Expect=2e-37]} {RNA1310_107478}
10. MligTC455_03081 39 0.81 Mlig455_026877, Mlig455_030777, Mlig455_030817

Neo: -

Age: -

 FO681492.1 2.553 - - 0.980 0.741 0.832 -

Mlig455_026877 {REF} {Length: 2007} {Pfam: C2 domain [PF00168.32, score=67.2]} {Human: ENSG00000277758, FO681492.1, synaptotagmin-15, [Score=92.8, Expect=1e-19]; ENSG00000204176, SYT15, synaptotagmin 15, [Score=92.4, Expect=1e-19]} {Mouse: ENSMUSG00000041479, Syt15, synaptotagmin XV, [Score=86.3, Expect=1e-17]} {Dmel: FBgn0004242, Syt1, Synaptotagmin 1, [Score=67.4, Expect=1e-11]} {Smed: dd_Smed_v6_16731_0_1, dd_Smed_v6_16731_0_1, [RH, Score=129, Expect=1e-32]} {RNA1509_21228} {RNA1310_103420} {RNA815_7856.1}

Mlig455_030777 {REF} {Length: 2035} {Pfam: C2 domain [PF00168.32, score=67.2]} {Human: ENSG00000277758, FO681492.1, synaptotagmin-15, [Score=94.0, Expect=6e-20]; ENSG00000204176, SYT15, synaptotagmin 15, [Score=93.6, Expect=5e-20]} {Mouse: ENSMUSG00000041479, Syt15, synaptotagmin XV, [Score=86.3, Expect=1e-17]} {Dmel: FBgn0004242, Syt1, Synaptotagmin 1, [Score=68.9, Expect=4e-12]} {Smed: dd_Smed_v6_16731_0_1, dd_Smed_v6_16731_0_1, [RH, Score=130, Expect=8e-33]} {RNA1509_21228} {RNA1310_103420} {RNA815_7856.1}

Mlig455_030817 {REF} {Length: 2853} {Pfam: C2 domain [PF00168.32, score=66.7]} {Human: ENSG00000277758, FO681492.1, synaptotagmin-15, [Score=92.8, Expect=1e-19]; ENSG00000204176, SYT15, synaptotagmin 15, [Score=92.8, Expect=1e-19]} {Mouse: ENSMUSG00000041479, Syt15, synaptotagmin XV, [Score=86.7, Expect=7e-18]} {Dmel: FBgn0004242, Syt1, Synaptotagmin 1, [Score=65.9, Expect=4e-11]} {Smed: dd_Smed_v6_16731_0_1, dd_Smed_v6_16731_0_1, [RH, Score=130, Expect=6e-33]} {RNA1509_47157} {RNA1310_77313} {RNA815_44967}
11. MligTC455_10667 475 9.89 Mlig455_060955

Neo: -

Age: -

 2.544 - - 0.950 0.726 0.868 - Mlig455_060955 {REF} {Length: 1952} {TRANSSPLICED} {Pfam: CIDE-N domain [PF02017.17, score=44.6]} {RNA1509_6031} {RNA1310_3667, RNA1509_6031} {RNA1509_6031, RNA815_5199}
12. MligTC455_33345 73 1.53 Mlig455_022775

Neo: -

Age: Up-Down-Down

 ITPR2 2.544 - - 0.987 0.824 0.733 - Mlig455_022775 {REF} {Length: 10477} {Pfam: RIH domain [PF01365.23, score=93.1]; RyR and IP3R Homology associated [PF08454.13, score=68.6]; Inositol 1,4,5-trisphosphate/ryanodine receptor [PF08709.13, score=68.1]; MIR domain [PF02815.21, score=57.0]} {Human: ENSG00000123104, ITPR2, inositol 1,4,5-trisphosphate receptor type 2, [Score=204, Expect=1e-51]} {Mouse: ENSMUSG00000030287, Itpr2, inositol 1,4,5-triphosphate receptor 2, [Score=206, Expect=3e-52]; ENSMUSG00000042644, Itpr3, inositol 1,4,5-triphosphate receptor 3, [Score=199, Expect=3e-50]} {Dmel: FBgn0010051, Itp-r83A, Inositol 1,4,5,-tris-phosphate receptor, [Score=157, Expect=1e-37]} {Celegans: WBGene00002173, itr-1, Inositol 1,4,5-trisphosphate receptor itr-1, [Score=146, Expect=2e-34]} {Smed: dd_Smed_v6_3814_1_1, dd_Smed_v6_3814_1_1, [RH, Score=3019, Expect=0.0]} {RNA1509_31887} {RNA1310_193.1} {RNA815_9899}
13. MligTC455_27594 80 1.67 Mlig455_026429

Neo: -

Age: -

 2.54 - - 0.982 - 0.783 0.775 Mlig455_026429 {REF} {Length: 3187} {Pfam: Otopetrin [PF03189.15, score=182.4]} {Dmel: FBgn0259150, CG42265, [Score=141, Expect=2e-34]} {Celegans: WBGene00015035, otpl-1, OToPetrin-Like, [Score=92.4, Expect=4e-19]} {Smed: dd_Smed_v6_13612_0_1, dd_Smed_v6_13612_0_1, [Score=238, Expect=4e-69]} {RNA1509_24533} {RNA1310_4254.1} {RNA815_23661}
14. MligTC455_52834 181 3.78 Mlig455_033318

Neo: -

Age: -

 CCDC112 2.489 - - 0.959 - 0.720 0.810 Mlig455_033318 {REF} {Length: 3199} {TRANSSPLICED} {Pfam: Transcriptional regulator, Out at first [PF14941.8, score=49.7]} {Human: ENSG00000164221, CCDC112, coiled-coil domain containing 112, [Score=184, Expect=2e-49]} {Mouse: ENSMUSG00000071855, Ccdc112, coiled-coil domain containing 112, [Score=174, Expect=3e-46]} {Smed: dd_Smed_v6_12448_0_1, dd_Smed_v6_12448_0_1, [RH, Score=201, Expect=2e-56]} {RNA1509_16362, RNA1509_36234, RNA1509_46670} {RNA1310_3182, RNA1509_16362, RNA1509_36234} {RNA1509_16362, RNA1509_36234, RNA815_6554}
15. MligTC455_54156 465 9.68 Mlig455_035955

Neo: -

Age: logFC(26M/2M)=-0.401

 PPP1R36 2.442 - - 0.959 0.752 0.731 - Mlig455_035955 {REF} {Length: 2382} {Pfam: Protein phosphatase 1 inhibitor [PF14895.8, score=139.0]} {Human: ENSG00000165807, PPP1R36, protein phosphatase 1 regulatory subunit 36, [RH, Score=191, Expect=1e-55]} {Mouse: ENSMUSG00000052221, Ppp1r36, protein phosphatase 1, regulatory subunit 36, [RH, Score=167, Expect=5e-47]} {RNA1509_6292} {RNA1310_2911.1, RNA1509_6292} {RNA1509_6292, RNA815_5971.1}
16. MligTC455_16602 96 2 Mlig455_009821, Mlig455_010361

Neo: -

Age: -

 2.419 - - 0.981 0.702 0.736 -

Mlig455_009821 {REF} {Length: 808} {NoTransDecoderORF} {RNA1509_56255} {RNA1310_14959.1} {RNA815_9852.1}

Mlig455_010361 {REF} {Length: 2044} {NoTransDecoderORF} {RNA1509_56255} {RNA1310_14959.1} {RNA815_9852.1}
17. MligTC455_22321 773 16.1 Mlig455_006890, Mlig455_017894, Mlig455_017901, Mlig455_017905

Neo: -

Age: Up-Down-Down

 UNC13A, UNC13B 1.927 - - 0.965 - 0.962 -

Mlig455_006890 {REF} {Length: 8483} {Pfam: MUN domain [PF06292.19, score=460.4]; C2 domain [PF00168.32, score=165.9]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=40.1]} {Human: ENSG00000198722, UNC13B, unc-13 homolog B, [RH, Score=1600, Expect=0.0]; ENSG00000130477, UNC13A, unc-13 homolog A, [RH, Score=1590, Expect=0.0]} {Mouse: ENSMUSG00000028456, Unc13b, unc-13 homolog B, [RH, Score=1595, Expect=0.0]; ENSMUSG00000034799, Unc13a, unc-13 homolog A, [RH, Score=1590, Expect=0.0]} {Dmel: FBgn0025726, unc-13, [RH, Score=1701, Expect=0.0]} {Celegans: WBGene00006752, unc-13, Phorbol ester/diacylglycerol-binding protein unc-13, [RH, Score=1489, Expect=0.0]} {Smed: dd_Smed_v6_11981_0_1, dd_Smed_v6_11981_0_1, [RH, Score=1793, Expect=0.0]} {RNA1509_25617} {RNA1310_453.1, RNA1509_25617} {RNA1509_25617, RNA815_1396}

Mlig455_017894 {REF} {Length: 10746} {Pfam: MUN domain [PF06292.19, score=459.7]; C2 domain [PF00168.32, score=146.8]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=39.7]} {Human: ENSG00000130477, UNC13A, unc-13 homolog A, [RH, Score=1583, Expect=0.0]; ENSG00000198722, UNC13B, unc-13 homolog B, [RH, Score=1581, Expect=0.0]} {Mouse: ENSMUSG00000034799, Unc13a, unc-13 homolog A, [RH, Score=1584, Expect=0.0]; ENSMUSG00000028456, Unc13b, unc-13 homolog B, [RH, Score=1576, Expect=0.0]} {Dmel: FBgn0025726, unc-13, [RH, Score=1668, Expect=0.0]} {Celegans: WBGene00006752, unc-13, Phorbol ester/diacylglycerol-binding protein unc-13, [RH, Score=1459, Expect=0.0]} {Smed: dd_Smed_v6_11981_0_1, dd_Smed_v6_11981_0_1, [RH, Score=1753, Expect=0.0]} {RNA1509_45330} {RNA1310_1692} {RNA815_1396}

Mlig455_017901 {REF} {Length: 7140} {Pfam: MUN domain [PF06292.19, score=460.5]; C2 domain [PF00168.32, score=136.3]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=40.6]} {Human: ENSG00000130477, UNC13A, unc-13 homolog A, [RH, Score=1582, Expect=0.0]; ENSG00000198722, UNC13B, unc-13 homolog B, [RH, Score=1579, Expect=0.0]} {Mouse: ENSMUSG00000034799, Unc13a, unc-13 homolog A, [RH, Score=1583, Expect=0.0]; ENSMUSG00000028456, Unc13b, unc-13 homolog B, [RH, Score=1574, Expect=0.0]} {Dmel: FBgn0025726, unc-13, [RH, Score=1667, Expect=0.0]} {Celegans: WBGene00006752, unc-13, Phorbol ester/diacylglycerol-binding protein unc-13, [RH, Score=1456, Expect=0.0]} {Smed: dd_Smed_v6_11981_0_1, dd_Smed_v6_11981_0_1, [RH, Score=1746, Expect=0.0]} {RNA1509_16665} {RNA1310_453.1} {RNA815_1396}

Mlig455_017905 {REF} {Length: 3674} {Pfam: C2 domain [PF00168.32, score=35.8]} {Human: ENSG00000130477, UNC13A, unc-13 homolog A, [Score=166, Expect=5e-41]} {Mouse: ENSMUSG00000034799, Unc13a, unc-13 homolog A, [Score=162, Expect=5e-40]; ENSMUSG00000028456, Unc13b, unc-13 homolog B, [Score=155, Expect=1e-37]} {Celegans: WBGene00006752, unc-13, Phorbol ester/diacylglycerol-binding protein unc-13, [Score=174, Expect=9e-44]} {Smed: dd_Smed_v6_11981_0_1, dd_Smed_v6_11981_0_1, [Score=207, Expect=3e-54]} {RNA1509_45330} {RNA1310_453.1} {RNA815_23416}
18. MligTC455_15592 549 11.44 Mlig455_023519, Mlig455_023621

Neo: -

Age: -

 IRF8 1.905 - - 0.948 - 0.957 -

Mlig455_023519 {REF} {Length: 3145} {Pfam: Interferon regulatory factor transcription factor [PF00605.19, score=52.6]; Interferon-regulatory factor 3 [PF10401.11, score=30.7]} {Human: ENSG00000140968, IRF8, interferon regulatory factor 8, [Score=50.1, Expect=8e-06]} {Mouse: ENSMUSG00000041515, Irf8, interferon regulatory factor 8, [Score=48.9, Expect=1e-05]} {Smed: dd_Smed_v6_6636_0_1, dd_Smed_v6_6636_0_1, [RH, Score=69.7, Expect=2e-12]} {RNA1509_19195} {RNA1310_22732} {RNA815_9876}

Mlig455_023621 {REF} {Length: 2477} {TRANSSPLICED} {Pfam: Interferon regulatory factor transcription factor [PF00605.19, score=52.6]; Interferon-regulatory factor 3 [PF10401.11, score=30.7]} {Human: ENSG00000140968, IRF8, interferon regulatory factor 8, [Score=50.1, Expect=8e-06]} {Mouse: ENSMUSG00000041515, Irf8, interferon regulatory factor 8, [Score=48.9, Expect=1e-05]} {Smed: dd_Smed_v6_6636_0_1, dd_Smed_v6_6636_0_1, [RH, Score=69.7, Expect=2e-12]} {RNA1509_19195} {RNA1310_22732} {RNA815_9876}
19. MligTC455_33199 144 3 Mlig455_068562

Neo: -

Age: -

 CAMKK2 1.897 - - 0.965 - 0.932 - Mlig455_068562 {REF} {Length: 3078} {Pfam: Protein kinase domain [PF00069.27, score=209.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=121.7]; Kinase-like [PF14531.8, score=30.4]; Fungal protein kinase [PF17667.3, score=19.0]} {Human: ENSG00000110931, CAMKK2, calcium/calmodulin dependent protein kinase kinase 2, [RH, Score=417, Expect=4e-138]} {Mouse: ENSMUSG00000029471, Camkk2, calcium/calmodulin-dependent protein kinase kinase 2, beta, [RH, Score=409, Expect=4e-135]; ENSMUSG00000020785, Camkk1, calcium/calmodulin-dependent protein kinase kinase 1, alpha, [RH, Score=394, Expect=1e-129]} {Dmel: FBgn0040056, CG17698, [RH, Score=402, Expect=1e-130]} {Celegans: WBGene00000518, ckk-1, Calcium/calmodulin-dependent protein kinase kinase, [RH, Score=414, Expect=3e-137]} {Smed: dd_Smed_v6_18437_0_1, dd_Smed_v6_18437_0_1, [RH, Score=367, Expect=3e-118]} {RNA1509_51718} {RNA1310_7593.1} {RNA815_7566}
20. MligTC455_37343 240 4.99 Mlig455_024086

Neo: -

Age: Up-Down-Up

Region-enriched R8: 2.659/0.04266

 1.876 - - 0.962 - 0.914 - Mlig455_024086 {REF} {Length: 4209} {RNA1509_36528, RNA1509_59718} {RNA1310_12514, RNA1509_36528, RNA1509_59718} {RNA1509_36528, RNA1509_59718, RNA815_21020}
21. MligTC455_18239 49 1.02 Mlig455_005306

Neo: -

Age: -

 SSTR5 1.868 - - 0.982 - 0.886 - Mlig455_005306 {REF} {Length: 1637} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=137.3]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=34.2]; Olfactory receptor [PF13853.8, score=25.8]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=22.6]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=21.2]} {Human: ENSG00000162009, SSTR5, somatostatin receptor 5, [Score=121, Expect=4e-30]; ENSG00000139874, SSTR1, somatostatin receptor 1, [Score=115, Expect=1e-27]} {Mouse: ENSMUSG00000037014, Sstr4, somatostatin receptor 4, [Score=120, Expect=1e-29]; ENSMUSG00000035431, Sstr1, somatostatin receptor 1, [Score=115, Expect=8e-28]; ENSMUSG00000047904, Sstr2, somatostatin receptor 2, [Score=115, Expect=3e-28]} {Dmel: FBgn0036789, AstC-R2, Allatostatin C receptor 2, [Score=132, Expect=4e-33]} {Celegans: WBGene00020086, npr-24, NeuroPeptide Receptor family, [Score=116, Expect=1e-28]} {Smed: dd_Smed_v6_16055_0_1, dd_Smed_v6_16055_0_1, [RH, Score=147, Expect=2e-40]} {RNA1310_89111}
22. MligTC455_51779 660 13.75 Mlig455_031396

Neo: -

Age: Up-Down-Down

Region-enriched R2: 2.441/0.00016

 CACNA1C 1.863 - - 0.899 - 0.964 - Mlig455_031396 {REF} {Length: 8157} {Pfam: Ion transport protein [PF00520.33, score=797.6]; Voltage gated calcium channel IQ domain [PF08763.13, score=101.0]; Voltage-dependent L-type calcium channel, IQ-associated [PF16905.7, score=100.3]; Polycystin cation channel [PF08016.14, score=31.5]} {Human: ENSG00000151067, CACNA1C, calcium voltage-gated channel subunit alpha1 C, [Score=1289, Expect=0.0]; ENSG00000285479, CACNA1C, calcium voltage-gated channel subunit alpha1 C, [Score=1289, Expect=0.0]; ENSG00000157388, CACNA1D, calcium voltage-gated channel subunit alpha1 D, [Score=1286, Expect=0.0]; ENSG00000081248, CACNA1S, calcium voltage-gated channel subunit alpha1 S, [Score=1273, Expect=0.0]} {Mouse: ENSMUSG00000051331, Cacna1c, calcium channel, voltage-dependent, L type, alpha 1C subunit, [Score=1294, Expect=0.0]; ENSMUSG00000015968, Cacna1d, calcium channel, voltage-dependent, L type, alpha 1D subunit, [Score=1288, Expect=0.0]; ENSMUSG00000031142, Cacna1f, calcium channel, voltage-dependent, alpha 1F subunit, [Score=1276, Expect=0.0]; ENSMUSG00000026407, Cacna1s, calcium channel, voltage-dependent, L type, alpha 1S subunit, [Score=1260, Expect=0.0]} {Dmel: FBgn0001991, Ca-alpha1D, Ca[2+]-channel protein alpha[[1]] subunit D, [Score=1292, Expect=0.0]} {Celegans: WBGene00006742, unc-2, High voltage activated calcium channel alpha-1 subunit, [RH, Score=1690, Expect=0.0]} {Smed: dd_Smed_v6_13295_0_1, dd_Smed_v6_13295_0_1, [RH, Score=2129, Expect=0.0]} {RNA1509_11510} {RNA1310_2184.1} {RNA815_2606}
23. MligTC455_13682 42 0.87 Mlig455_030673

Neo: -

Age: -

 1.862 - - 0.969 - 0.893 - Mlig455_030673 {REF} {Length: 2472} {Pfam: gag-polyprotein putative aspartyl protease [PF13975.8, score=21.9]} {RNA1509_51609} {RNA1310_3461} {RNA815_16498}
24. MligTC455_09595 48 1.01 Mlig455_030009

Neo: -

Age: -

 OPRM1 1.855 - - 0.981 - 0.874 - Mlig455_030009 {REF} {Length: 1508} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=44.4]; Serpentine type 7TM GPCR chemoreceptor Sra [PF02117.18, score=19.7]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=19.6]} {Human: ENSG00000112038, OPRM1, opioid receptor mu 1, [Score=56.2, Expect=5e-08]} {Mouse: ENSMUSG00000000766, Oprm1, opioid receptor, mu 1, [Score=54.7, Expect=9e-08]} {Celegans: WBGene00021510, frpr-19, FMRFamide Peptide Receptor family, [Score=47.8, Expect=7e-06]} {RNA1310_43388} {RNA815_47203}
25. MligTC455_53021 248 5.17 Mlig455_039734, Mlig455_060892

Neo: -

Age: Down-Down-Up

 1.853 - - 0.956 - 0.897 -

Mlig455_039734 {REF} {Length: 1487} {TRANSSPLICED} {RNA1509_24093} {RNA1310_26642} {RNA815_14301}

Mlig455_060892 {REF} {Length: 3436} {RNA1509_24093} {RNA1310_26642} {RNA815_14301}
26. MligTC455_37342 203 4.23 Mlig455_024018

Neo: -

Age: -

 1.851 - - 0.971 - 0.880 - Mlig455_024018 {REF} {Length: 1374} {RNA1509_59718} {RNA1310_33285} {RNA815_22262}
27. MligTC455_19585 83 1.72 Mlig455_041765

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.499

 PCDH11X 1.838 - - 0.980 - 0.858 - Mlig455_041765 {REF} {Length: 5069} {Pfam: Cadherin domain [PF00028.19, score=307.9]; Cadherin-like [PF08266.14, score=46.0]; Cadherin-like [PF16184.7, score=24.6]} {Human: ENSG00000102290, PCDH11X, protocadherin 11 X-linked, [Score=294, Expect=4e-84]; ENSG00000184226, PCDH9, protocadherin 9, [Score=293, Expect=4e-84]; ENSG00000099715, PCDH11Y, protocadherin 11 Y-linked, [Score=290, Expect=9e-83]} {Mouse: ENSMUSG00000034755, Pcdh11x, protocadherin 11 X-linked, [RH, Score=301, Expect=7e-86]} {Dmel: FBgn0001075, ft, fat, [Score=242, Expect=9e-66]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=206, Expect=4e-54]} {Smed: dd_Smed_v6_15181_0_1, dd_Smed_v6_15181_0_1, [RH, Score=275, Expect=2e-78]} {RNA1509_46943} {RNA1310_9721, RNA1509_46943} {RNA1509_46943, RNA815_23754}
28. MligTC455_36317 545 11.35 Mlig455_025049

Neo: -

Age: -

 GLB1 1.836 - - 0.957 - 0.879 - Mlig455_025049 {REF} {Length: 2498} {Pfam: Glycosyl hydrolases family 35 [PF01301.21, score=364.2]; Beta-galactosidase [PF02449.17, score=40.5]; Beta-galactosidase jelly roll domain [PF13364.8, score=31.4]} {Human: ENSG00000170266, GLB1, galactosidase beta 1, [RH, Score=482, Expect=1e-161]} {Mouse: ENSMUSG00000045594, Glb1, galactosidase, beta 1, [RH, Score=491, Expect=1e-165]} {Dmel: FBgn0001089, Gal, beta galactosidase, [RH, Score=412, Expect=7e-135]} {Celegans: WBGene00011832, bgal-1, Beta-galactosidase, [RH, Score=384, Expect=1e-124]} {Smed: dd_Smed_v6_4056_0_1, dd_Smed_v6_4056_0_1, [RH, Score=514, Expect=4e-175]} {RNA1509_37267} {RNA1310_9080.2, RNA1509_37267} {RNA1509_37267, RNA815_6506}
29. MligTC455_31661 121 2.52 Mlig455_046099, Mlig455_056831

Neo: -

Age: Down-Up-Down

 1.83 - - 0.975 0.855 - -

Mlig455_046099 {REF} {Length: 1339} {RNA1509_58475} {RNA1310_11210} {RNA815_47142}

Mlig455_056831 {REF} {Length: 2263} {TRANSSPLICED} {RNA1509_58475} {RNA1310_11210} {RNA815_24316.1}
30. MligTC455_31847 661 13.78 Mlig455_025501, Mlig455_070503

Neo: -

Age: Down-Up-Down

 KCNMA1 1.829 - - 0.952 - 0.877 -

Mlig455_025501 {REF} {Length: 4552} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=85.2]; Ion channel [PF07885.18, score=43.4]; Ion transport protein [PF00520.33, score=34.6]; TrkA-N domain [PF02254.20, score=22.5]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=488, Expect=4e-154]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=335, Expect=3e-97]} {Dmel: FBgn0003429, slo, slowpoke, [Score=484, Expect=1e-151]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=454, Expect=9e-141]} {Smed: dd_Smed_v6_5509_0_1, dd_Smed_v6_5509_0_1, [Score=476, Expect=1e-149]} {RNA1509_14763} {RNA1310_2844.1} {RNA815_830}

Mlig455_070503 {REF} {Length: 4866} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=85.2]; Ion channel [PF07885.18, score=43.4]; Ion transport protein [PF00520.33, score=34.6]; TrkA-N domain [PF02254.20, score=22.5]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=488, Expect=4e-154]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=335, Expect=3e-97]} {Dmel: FBgn0003429, slo, slowpoke, [Score=484, Expect=1e-151]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=454, Expect=9e-141]} {Smed: dd_Smed_v6_5509_0_1, dd_Smed_v6_5509_0_1, [Score=476, Expect=1e-149]} {RNA1509_14763} {RNA1310_2844.1, RNA1509_14763} {RNA1509_14763, RNA815_830}
31. MligTC455_24422 159 3.31 Mlig455_014156

Neo: -

Age: -

 TANC2 1.828 - - 0.969 - - 0.859 Mlig455_014156 {REF} {Length: 4949} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=57.6]; Ankyrin repeats (many copies) [PF13637.8, score=49.0]; Mab-21 protein [PF03281.16, score=44.5]; Ankyrin repeat [PF13606.8, score=39.6]; Ankyrin repeat [PF00023.32, score=35.4]; Ankyrin repeats (many copies) [PF13857.8, score=31.6]} {Human: ENSG00000170921, TANC2, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2, [Score=72.0, Expect=6e-12]} {Mouse: ENSMUSG00000078487, Ankrd65, ankyrin repeat domain 65, [Score=72.8, Expect=6e-13]; ENSMUSG00000053580, Tanc2, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2, [Score=72.0, Expect=4e-12]} {Dmel: FBgn0041096, rols, rolling pebbles, [Score=68.2, Expect=4e-11]} {Celegans: WBGene00007252, mlt-2, [Score=63.2, Expect=8e-10]} {Smed: dd_Smed_v6_21003_0_1, dd_Smed_v6_21003_0_1, [Score=62.0, Expect=2e-09]} {RNA1509_17002} {RNA1310_2398} {RNA815_4370}
32. MligTC455_13094 121 2.52 Mlig455_005442, Mlig455_005513

Neo: -

Age: Up-Up-Down

 1.82 - - 0.964 - 0.856 -

Mlig455_005442 {REF} {Length: 3816} {Smed: dd_Smed_v6_15433_0_1, dd_Smed_v6_15433_0_1, [Score=141, Expect=1e-34]} {RNA1509_41201} {RNA1310_51044} {RNA815_32534}

Mlig455_005513 {REF} {Length: 685} {NoTransDecoderORF} {RNA1310_56412} {RNA815_32534}
33. MligTC455_43733 869 18.1 Mlig455_034271, Mlig455_034309

Neo: -

Age: Down-Up-Up

 1.815 - - 0.976 - 0.839 -

Mlig455_034271 {REF} {Length: 2291} {Pfam: Protein kinase domain [PF00069.27, score=27.1]} {RNA1509_10827} {RNA1310_17438} {RNA815_7916}

Mlig455_034309 {REF} {Length: 2300} {RNA1509_10827} {RNA1310_9412} {RNA815_7916}
34. MligTC455_43734 871 18.15 Mlig455_067307, Mlig455_067323

Neo: -

Age: logFC(26M/2M)=-0.518

 SIK3 1.815 - - 0.975 - 0.840 -

Mlig455_067307 {REF} {Length: 3849} {Pfam: Protein kinase domain [PF00069.27, score=49.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=24.7]} {Human: ENSG00000160584, SIK3, SIK family kinase 3, [Score=71.6, Expect=3e-12]; ENSG00000007047, MARK4, microtubule affinity regulating kinase 4, [Score=70.5, Expect=5e-12]} {Mouse: ENSMUSG00000034135, Sik3, SIK family kinase 3, [Score=70.5, Expect=4e-12]; ENSMUSG00000030397, Mark4, MAP/microtubule affinity regulating kinase 4, [Score=70.1, Expect=5e-12]} {Dmel: FBgn0025625, Sik2, Salt-inducible kinase 2, [Score=61.6, Expect=2e-09]} {Celegans: WBGene00006814, unc-82, [Score=61.6, Expect=2e-09]} {Smed: dd_Smed_v6_5124_0_2, dd_Smed_v6_5124_0_2, [Score=68.6, Expect=8e-12]} {RNA1509_10827} {RNA1310_9412, RNA1509_10827} {RNA1509_10827, RNA815_7916}

Mlig455_067323 {REF} {Length: 2835} {Pfam: Protein kinase domain [PF00069.27, score=49.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=24.7]} {Human: ENSG00000160584, SIK3, SIK family kinase 3, [Score=71.6, Expect=3e-12]; ENSG00000007047, MARK4, microtubule affinity regulating kinase 4, [Score=70.5, Expect=5e-12]} {Mouse: ENSMUSG00000034135, Sik3, SIK family kinase 3, [Score=70.5, Expect=4e-12]; ENSMUSG00000030397, Mark4, MAP/microtubule affinity regulating kinase 4, [Score=70.1, Expect=5e-12]} {Dmel: FBgn0025625, Sik2, Salt-inducible kinase 2, [Score=61.6, Expect=2e-09]} {Celegans: WBGene00006814, unc-82, [Score=61.6, Expect=2e-09]} {Smed: dd_Smed_v6_5124_0_2, dd_Smed_v6_5124_0_2, [Score=68.6, Expect=8e-12]} {RNA1509_10827} {RNA1310_9412} {RNA815_7916}
35. MligTC455_49690 72 1.5 Mlig455_068367

Neo: -

Age: Down-Down-Up

 1.815 - - 0.964 - 0.851 - Mlig455_068367 {REF} {Length: 1546} {Smed: dd_Smed_v6_8297_0_1, dd_Smed_v6_8297_0_1, [RH, Score=53.1, Expect=2e-09]} {RNA1509_38073} {RNA1310_34998} {RNA815_20391}
36. MligTC455_36628 477 9.95 Mlig455_047554, Mlig455_047565

Neo: -

Age: -

Region-enriched R4: 2.246/0.02774

 1.814 - - 0.864 - 0.950 -

Mlig455_047554 {REF} {Length: 2406} {Smed: dd_Smed_v6_2397_0_1, dd_Smed_v6_2397_0_1, [Score=367, Expect=6e-122]} {RNA1509_25988, RNA1509_46354} {RNA1310_10207, RNA1509_25988} {RNA1509_25988, RNA815_3595}

Mlig455_047565 {REF} {Length: 1169} {Smed: dd_Smed_v6_2397_0_1, dd_Smed_v6_2397_0_1, [Score=92.4, Expect=7e-23]} {RNA1509_46354} {RNA1310_10207} {RNA815_3595}
37. MligTC455_24614 62 1.29 Mlig455_015091, Mlig455_015206

Neo: -

Age: logFC(26M/2M)=-0.441

Region-enriched R4: 7.131/0.00032

Regeneration-downregulated R4: -4.923

Regeneration-depleted R4: -4.923

 ECT2 1.811 - - 0.959 0.852 - -

Mlig455_015091 {REF} {Length: 3092} {Pfam: RhoGEF domain [PF00621.22, score=124.1]; Domain of unknown function (DUF4795) [PF16043.7, score=21.0]; Winged helix-turn helix [PF13592.8, score=19.5]} {Human: ENSG00000114346, ECT2, epithelial cell transforming 2, [Score=78.6, Expect=2e-14]} {Mouse: ENSMUSG00000020640, Itsn2, intersectin 2, [Score=78.6, Expect=2e-14]; ENSMUSG00000027699, Ect2, ect2 oncogene, [Score=74.7, Expect=2e-13]} {Dmel: FBgn0003041, pbl, pebble, [Score=57.0, Expect=6e-08]} {Celegans: WBGene00002297, ect-2, ECT2 (Mammalian Rho GEF) homolog, [Score=67.0, Expect=3e-11]} {Smed: dd_Smed_v6_2922_0_1, dd_Smed_v6_2922_0_1, [Score=59.7, Expect=5e-09]} {RNA1509_21158} {RNA1310_6370} {RNA815_1845}

Mlig455_015206 {REF} {Length: 3091} {Pfam: RhoGEF domain [PF00621.22, score=124.1]; Domain of unknown function (DUF4795) [PF16043.7, score=21.0]; Winged helix-turn helix [PF13592.8, score=19.5]} {Human: ENSG00000114346, ECT2, epithelial cell transforming 2, [Score=78.6, Expect=2e-14]} {Mouse: ENSMUSG00000020640, Itsn2, intersectin 2, [Score=78.6, Expect=2e-14]; ENSMUSG00000027699, Ect2, ect2 oncogene, [Score=74.7, Expect=2e-13]} {Dmel: FBgn0003041, pbl, pebble, [Score=57.0, Expect=6e-08]} {Celegans: WBGene00002297, ect-2, ECT2 (Mammalian Rho GEF) homolog, [Score=67.0, Expect=3e-11]} {Smed: dd_Smed_v6_2922_0_1, dd_Smed_v6_2922_0_1, [Score=59.7, Expect=5e-09]} {RNA1509_21158, RNA1509_7033} {RNA1310_6370, RNA1509_21158, RNA1509_7033} {RNA1509_21158, RNA1509_7033, RNA815_1845}
38. MligTC455_42092 367 7.65 Mlig455_004422, Mlig455_004425, Mlig455_037263

Neo: -

Age: Up-Down-Up

 KIAA1217 1.808 - - 0.967 - 0.841 -

Mlig455_004422 {REF} {Length: 2718} {Human: ENSG00000120549, KIAA1217, KIAA1217, [Score=56.2, Expect=2e-07]} {Mouse: ENSMUSG00000036617, Etl4, enhancer trap locus 4, [Score=55.1, Expect=3e-07]; ENSMUSG00000038453, Srcin1, SRC kinase signaling inhibitor 1, [Score=52.8, Expect=2e-06]} {Dmel: FBgn0023531, CG32809, [Score=52.0, Expect=2e-06]} {RNA1310_27406} {RNA815_32070}

Mlig455_004425 {REF} {Length: 1652} {RNA1310_27406} {RNA815_32070}

Mlig455_037263 {REF} {Length: 1802} {RNA1310_27406} {RNA815_32070}
39. MligTC455_20209 78 1.63 Mlig455_034769

Neo: -

Age: -

 1.807 - - 0.970 0.837 - - Mlig455_034769 {REF} {Length: 2528} {Pfam: 7 transmembrane sweet-taste receptor of 3 GCPR [PF00003.24, score=55.9]} {RNA1310_29903.1} {RNA815_52525}
40. MligTC455_31551 284 5.92 Mlig455_057535

Neo: -

Age: Up-Down-Down

 RBM10 1.807 0.828 - 0.979 - - - Mlig455_057535 {REF} {Length: 4657} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=50.7]; OCRE domain [PF17780.3, score=47.3]; G-patch domain [PF01585.25, score=44.7]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=19.3]} {Human: ENSG00000182872, RBM10, RNA binding motif protein 10, [RH, Score=327, Expect=4e-96]} {Mouse: ENSMUSG00000031060, Rbm10, RNA binding motif protein 10, [RH, Score=333, Expect=2e-99]} {Dmel: FBgn0031319, CG4896, [RH, Score=294, Expect=5e-85]} {Celegans: WBGene00020346, rbm-5, RNA Binding Motif protein homolog, [RH, Score=114, Expect=2e-25]} {Smed: dd_Smed_v6_2392_0_4, dd_Smed_v6_2392_0_4, [RH, Score=207, Expect=9e-56]} {RNA1509_10003} {RNA1310_1240.1} {RNA815_5113}
41. MligTC455_13927 79 1.65 Mlig455_025242, Mlig455_025623

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.383

 KIF1B 1.806 - - 0.977 - 0.829 -

Mlig455_025242 {REF} {Length: 3364} {Pfam: FHA domain [PF00498.28, score=31.2]; Kinesin protein 1B [PF12423.10, score=29.5]} {Human: ENSG00000054523, KIF1B, kinesin family member 1B, [Score=52.4, Expect=2e-06]; ENSG00000197892, KIF13B, kinesin family member 13B, [Score=51.6, Expect=4e-06]} {Mouse: ENSMUSG00000087236, Kif28, kinesin family member 28, [Score=160, Expect=5e-41]} {Dmel: FBgn0019968, Khc-73, Kinesin heavy chain 73, [Score=58.2, Expect=2e-08]} {Celegans: WBGene00002218, klp-6, Kinesin-like protein, [Score=210, Expect=2e-58]} {Smed: dd_Smed_v6_20223_0_1, dd_Smed_v6_20223_0_1, [Score=348, Expect=3e-110]} {RNA1310_9866} {RNA815_27415}

Mlig455_025623 {REF} {Length: 4205} {Pfam: Kinesin motor domain [PF00225.25, score=345.1]; Microtubule binding [PF16796.7, score=70.6]; FHA domain [PF00498.28, score=30.2]; Kinesin-associated [PF16183.7, score=29.6]; Kinesin protein 1B [PF12423.10, score=28.9]} {Human: ENSG00000054523, KIF1B, kinesin family member 1B, [Score=464, Expect=6e-145]; ENSG00000130294, KIF1A, kinesin family member 1A, [Score=450, Expect=1e-135]; ENSG00000129250, KIF1C, kinesin family member 1C, [Score=448, Expect=2e-139]} {Mouse: ENSMUSG00000087236, Kif28, kinesin family member 28, [RH, Score=598, Expect=0.0]} {Dmel: FBgn0019968, Khc-73, Kinesin heavy chain 73, [Score=441, Expect=6e-132]} {Celegans: WBGene00002218, klp-6, Kinesin-like protein, [Score=703, Expect=0.0]} {Smed: dd_Smed_v6_12573_0_1, dd_Smed_v6_12573_0_1, [Score=806, Expect=0.0]} {RNA1509_18998} {RNA1310_9866} {RNA815_31497}
42. MligTC455_28518 184 3.84 Mlig455_068682

Neo: -

Age: Down-Down-Up

 ANKRD50 1.806 - - 0.972 0.834 - - Mlig455_068682 {REF} {Length: 5526} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=230.6]; Ankyrin repeats (many copies) [PF13637.8, score=137.6]; Ankyrin repeat [PF00023.32, score=109.8]; Ankyrin repeats (many copies) [PF13857.8, score=106.4]; Ankyrin repeat [PF13606.8, score=102.1]; Mab-21 protein [PF03281.16, score=30.7]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=158, Expect=1e-38]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=157, Expect=2e-38]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=135, Expect=8e-33]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=134, Expect=1e-31]} {Smed: dd_Smed_v6_6201_0_1, dd_Smed_v6_6201_0_1, [Score=140, Expect=6e-34]} {RNA1509_18101} {RNA1310_3035.1, RNA1509_18101} {RNA1509_18101, RNA815_4096}
43. MligTC455_28517 169 3.52 Mlig455_032503

Neo: -

Age: -

 1.799 - - 0.972 0.827 - - Mlig455_032503 {REF} {Length: 728} {NoTransDecoderORF} {RNA1310_54604.1} {RNA815_39231}
44. MligTC455_17160 332 6.92 Mlig455_003949

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=2.060

 FAM20B 1.798 - - 0.973 - - 0.825 Mlig455_003949 {REF} {Length: 3341} {TRANSSPLICED} {Pfam: Golgi casein kinase, C-terminal, Fam20 [PF06702.14, score=172.2]; Ribosomal protein L6e [PF01159.21, score=113.1]; Ribosomal protein L6, N-terminal domain [PF03868.17, score=21.8]} {Human: ENSG00000116199, FAM20B, FAM20B, glycosaminoglycan xylosylkinase, [RH, Score=224, Expect=2e-65]} {Mouse: ENSMUSG00000033557, Fam20b, family with sequence similarity 20, member B, [RH, Score=218, Expect=2e-63]} {Dmel: FBgn0039857, RpL6, Ribosomal protein L6, [RH, Score=211, Expect=6e-63]} {Celegans: WBGene00004417, rpl-6, 60S ribosomal protein L6, [Score=143, Expect=7e-39]} {Smed: dd_Smed_v6_839_0_1, dd_Smed_v6_839_0_1, [RH, Score=170, Expect=2e-47]} {RNA1509_31893, RNA1509_34793} {RNA1310_20853, RNA1509_34793} {RNA1509_34793, RNA815_8370}
45. MligTC455_19769 57 1.19 Mlig455_052386

Neo: -

Age: -

 1.798 - - 0.954 - - 0.844 Mlig455_052386 {REF} {Length: 2394} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=48.5]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=27.5]} {RNA1310_19077.2} {RNA815_23521}
46. MligTC455_52722 1007 20.97 Mlig455_019980, Mlig455_038108

Neo: -

Age: -

 CELF3 1.798 - - 0.845 - 0.953 -

Mlig455_019980 {REF} {Length: 4713} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=125.3]} {Human: ENSG00000159409, CELF3, CUGBP Elav-like family member 3, [Score=317, Expect=6e-103]; ENSG00000161082, CELF5, CUGBP Elav-like family member 5, [Score=315, Expect=8e-102]} {Mouse: ENSMUSG00000028137, Celf3, CUGBP, Elav-like family member 3, [Score=319, Expect=2e-103]; ENSMUSG00000024268, Celf4, CUGBP, Elav-like family member 4, [Score=312, Expect=1e-100]} {Dmel: FBgn0000114, bru1, bruno 1, [Score=243, Expect=2e-73]} {Celegans: WBGene00006807, unc-75, Putative RNA-binding protein, [RH, Score=172, Expect=3e-48]} {Smed: dd_Smed_v6_11349_0_1, dd_Smed_v6_11349_0_1, [RH, Score=366, Expect=1e-122]} {RNA1509_17477} {RNA1310_8180} {RNA815_3761.1}

Mlig455_038108 {REF} {Length: 3254} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=125.3]} {Human: ENSG00000159409, CELF3, CUGBP Elav-like family member 3, [Score=317, Expect=6e-103]; ENSG00000161082, CELF5, CUGBP Elav-like family member 5, [Score=315, Expect=8e-102]} {Mouse: ENSMUSG00000028137, Celf3, CUGBP, Elav-like family member 3, [Score=319, Expect=2e-103]; ENSMUSG00000024268, Celf4, CUGBP, Elav-like family member 4, [Score=312, Expect=1e-100]} {Dmel: FBgn0000114, bru1, bruno 1, [Score=243, Expect=2e-73]} {Celegans: WBGene00006807, unc-75, Putative RNA-binding protein, [RH, Score=172, Expect=3e-48]} {Smed: dd_Smed_v6_11349_0_1, dd_Smed_v6_11349_0_1, [RH, Score=366, Expect=1e-122]} {RNA1509_17477} {RNA1310_2810} {RNA815_3761.1}
47. MligTC455_50737 530 11.05 Mlig455_048544

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.397

 MXI1 1.792 - - 0.964 0.828 - - Mlig455_048544 {REF} {Length: 3190} {tRNA: Val(CAC),pseudo, score=21.1} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=38.9]} {Human: ENSG00000119950, MXI1, MAX interactor 1, dimerization protein, [Score=59.3, Expect=4e-10]} {Mouse: ENSMUSG00000025025, Mxi1, MAX interactor 1, dimerization protein, [Score=60.5, Expect=1e-10]; ENSMUSG00000001156, Mxd1, MAX dimerization protein 1, [Score=58.9, Expect=7e-10]} {Dmel: FBgn0023215, Mnt, [Score=50.4, Expect=1e-06]} {Celegans: WBGene00003163, mdl-1, MAD-Like; MAD-like-1 homolog, [Score=47.0, Expect=6e-06]} {Smed: dd_Smed_v6_4415_0_1, dd_Smed_v6_4415_0_1, [RH, Score=69.3, Expect=1e-13]} {RNA1509_21599} {RNA1310_15507} {RNA815_27395}
48. MligTC455_10666 1029 21.43 Mlig455_033815, Mlig455_036255

Neo: -

Age: Down-Up-Down

 1.788 - - 0.951 - 0.837 -

Mlig455_033815 {REF} {Length: 2235} {Pfam: CIDE-N domain [PF02017.17, score=45.6]} {RNA1509_6031} {RNA1310_3667} {RNA815_5199}

Mlig455_036255 {REF} {Length: 1884} {Pfam: CIDE-N domain [PF02017.17, score=46.3]} {RNA1509_6031} {RNA1310_3667} {RNA815_5199}
49. MligTC455_52319 228 4.76 Mlig455_021474, Mlig455_063234, Mlig455_067359

Neo: -

Age: Down-Up-Down

Region-enriched R4: 3.056/0.03841

 1.786 - - 0.988 - 0.798 -

Mlig455_021474 {REF} {Length: 1135} {RNA1509_6241} {RNA1310_26979} {RNA815_23904}

Mlig455_063234 {REF} {Length: 915} {RNA1509_6241} {RNA1310_26979} {RNA815_23904}

Mlig455_067359 {REF} {Length: 794} {RNA1310_26979} {RNA815_23904}
50. MligTC455_54026 99 2.07 Mlig455_025843, Mlig455_025903

Neo: -

Age: -

 1.785 - - 0.980 - 0.805 -

Mlig455_025843 {REF} {Length: 2505} {TRANSSPLICED} {Pfam: Hsp20/alpha crystallin family [PF00011.23, score=91.5]; HSP20-like domain found in ArsA [PF17886.3, score=30.3]} {Dmel: FBgn0001225, Hsp26, Heat shock protein 26, [RH, Score=57.8, Expect=8e-10]} {Celegans: WBGene00008592, F08H9.4, [RH, Score=60.5, Expect=2e-11]} {Smed: dd_Smed_v6_1039_0_1, dd_Smed_v6_1039_0_1, [RH, Score=101, Expect=2e-25]} {RNA1509_26837} {RNA1310_48105} {RNA815_21766}

Mlig455_025903 {REF} {Length: 2459} {TRANSSPLICED} {Pfam: Hsp20/alpha crystallin family [PF00011.23, score=91.5]; HSP20-like domain found in ArsA [PF17886.3, score=30.3]} {Dmel: FBgn0001225, Hsp26, Heat shock protein 26, [RH, Score=57.8, Expect=8e-10]} {Celegans: WBGene00008592, F08H9.4, [RH, Score=60.8, Expect=2e-11]} {Smed: dd_Smed_v6_1039_0_1, dd_Smed_v6_1039_0_1, [RH, Score=101, Expect=2e-25]} {RNA1509_33990} {RNA1310_42388.1} {RNA815_21766}
51. MligTC455_14212 39 0.81 Mlig455_037115, Mlig455_038532

Neo: -

Age: Down-Up-Up

 ACSF2 1.78 - - - - 0.973 0.807

Mlig455_037115 {REF} {Length: 2253} {Pfam: AMP-binding enzyme [PF00501.30, score=225.7]; AMP-binding enzyme C-terminal domain [PF13193.8, score=31.1]; GH3 auxin-responsive promoter [PF03321.15, score=22.5]} {Human: ENSG00000167107, ACSF2, acyl-CoA synthetase family member 2, [Score=147, Expect=1e-37]} {Mouse: ENSMUSG00000076435, Acsf2, acyl-CoA synthetase family member 2, [Score=159, Expect=1e-41]} {Dmel: FBgn0031703, CG12512, [Score=128, Expect=3e-31]} {Celegans: WBGene00018488, acs-1, Fatty Acid CoA Synthetase family, [Score=174, Expect=1e-47]} {Smed: dd_Smed_v6_7927_0_1, dd_Smed_v6_7927_0_1, [Score=103, Expect=2e-23]} {RNA1509_32889} {RNA1310_11338} {RNA815_4053}

Mlig455_038532 {REF} {Length: 2353} {Pfam: AMP-binding enzyme [PF00501.30, score=220.9]; AMP-binding enzyme C-terminal domain [PF13193.8, score=33.1]; GH3 auxin-responsive promoter [PF03321.15, score=22.3]} {Human: ENSG00000167107, ACSF2, acyl-CoA synthetase family member 2, [Score=155, Expect=4e-40]} {Mouse: ENSMUSG00000076435, Acsf2, acyl-CoA synthetase family member 2, [Score=166, Expect=7e-44]} {Dmel: FBgn0031703, CG12512, [Score=134, Expect=6e-33]} {Celegans: WBGene00018488, acs-1, Fatty Acid CoA Synthetase family, [Score=182, Expect=4e-50]} {Smed: dd_Smed_v6_7927_0_1, dd_Smed_v6_7927_0_1, [Score=103, Expect=3e-23]} {RNA1509_32889} {RNA1310_11338, RNA1509_32889} {RNA1509_32889, RNA815_4053}
52. MligTC455_07619 86 1.79 Mlig455_046331

Neo: -

Age: -

 1.779 - - 0.986 - 0.793 - Mlig455_046331 {REF} {Length: 231} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_46130} {RNA1310_1262.2} {RNA815_4161}
53. MligTC455_37798 389 8.1 Mlig455_060511

Neo: -

Age: Down-Up-Down

 1.778 - - 0.984 - - 0.794 Mlig455_060511 {REF} {Length: 3180} {RNA1509_15445, RNA1509_31771} {RNA1310_35217, RNA1509_15445, RNA1509_31771} {RNA1509_15445, RNA1509_31771, RNA815_22565}
54. MligTC455_17235 216 4.51 Mlig455_058265

Neo: -

Age: -

 ANO7 1.777 - - - - 0.952 0.825 Mlig455_058265 {REF} {Length: 1888} {Pfam: Calcium-activated chloride channel [PF04547.14, score=264.3]} {Human: ENSG00000146205, ANO7, anoctamin 7, [Score=394, Expect=4e-129]} {Mouse: ENSMUSG00000034107, Ano7, anoctamin 7, [Score=392, Expect=9e-130]} {Dmel: FBgn0038721, subdued, [Score=268, Expect=5e-82]} {Celegans: WBGene00013326, anoh-2, Anoctamin, [Score=85.1, Expect=9e-18]} {Smed: dd_Smed_v6_19189_0_1, dd_Smed_v6_19189_0_1, [Score=476, Expect=2e-164]} {RNA1509_15570} {RNA1310_7822} {RNA815_20477}
55. MligTC455_32941 211 4.39 Mlig455_059841

Neo: -

Age: Up-Down-Down

 GRIK2 1.775 - - 0.980 0.795 - - Mlig455_059841 {REF} {Length: 5097} {Pfam: Ligand-gated ion channel [PF00060.28, score=186.4]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=131.9]; Receptor family ligand binding region [PF01094.30, score=83.3]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=67.8]; Periplasmic binding protein [PF13458.8, score=21.4]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [RH, Score=640, Expect=0.0]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [RH, Score=629, Expect=0.0]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [RH, Score=629, Expect=0.0]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [RH, Score=639, Expect=0.0]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [RH, Score=628, Expect=0.0]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [RH, Score=623, Expect=0.0]} {Dmel: FBgn0038837, CG3822, [RH, Score=624, Expect=0.0]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [RH, Score=464, Expect=7e-149]} {Smed: dd_Smed_v6_8816_0_1, dd_Smed_v6_8816_0_1, [RH, Score=702, Expect=0.0]} {RNA1509_25923} {RNA1310_4023.1, RNA1509_25923} {RNA1509_25923, RNA815_3049.1}
56. MligTC455_34279 55 1.15 Mlig455_056988

Neo: -

Age: -

 ZBTB16 1.775 - - 0.984 0.791 - - Mlig455_056988 {REF} {Length: 3794} {Pfam: C2H2-type zinc-finger domain [PF13909.8, score=57.5]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=23.3]} {Human: ENSG00000109906, ZBTB16, zinc finger and BTB domain containing 16, [Score=52.8, Expect=2e-06]; ENSG00000084093, REST, RE1 silencing transcription factor, [Score=52.0, Expect=5e-06]} {Mouse: ENSMUSG00000026135, Zfp142, zinc finger protein 142, [Score=62.4, Expect=3e-09]} {Dmel: FBgn0262160, CG9932, [RH, Score=66.6, Expect=9e-11]} {Celegans: WBGene00001824, hbl-1, Hunchback-like protein, [Score=50.4, Expect=6e-06]} {Smed: dd_Smed_v6_36433_0_1, dd_Smed_v6_36433_0_1, [Score=176, Expect=9e-48]} {RNA1509_19024} {RNA1310_45424} {RNA815_39699}
57. MligTC455_42356 167 3.48 Mlig455_039463

Neo: -

Age: Up-Down-Down

 MEPCE 1.774 - - 0.981 - - 0.793 Mlig455_039463 {REF} {Length: 2698} {TRANSSPLICED} {Pfam: Bicoid-interacting protein 3 (Bin3) [PF06859.14, score=111.1]; Methyltransferase domain [PF13649.8, score=35.5]; Methyltransferase domain [PF08242.14, score=32.8]; Methyltransferase domain [PF13489.8, score=31.7]; Methyltransferase domain [PF13847.8, score=31.1]; Methyltransferase domain [PF08241.14, score=30.0]; Ribosomal protein L11 methyltransferase (PrmA) [PF06325.15, score=20.7]; Methyltransferase small domain [PF05175.16, score=20.1]} {Human: ENSG00000146834, MEPCE, methylphosphate capping enzyme, [Score=171, Expect=3e-45]} {Mouse: ENSMUSG00000029726, Mepce, methylphosphate capping enzyme, [Score=171, Expect=2e-45]} {Dmel: FBgn0037368, CG1239, [Score=145, Expect=3e-39]} {Celegans: WBGene00012469, Y17G7B.18, Probable RNA methyltransferase Y17G7B.18, [Score=162, Expect=2e-44]} {Smed: dd_Smed_v6_8153_0_1, dd_Smed_v6_8153_0_1, [RH, Score=125, Expect=4e-31]} {RNA1509_14163} {RNA1310_14404.2, RNA1509_14163} {RNA1509_14163, RNA815_5431}
58. MligTC455_43284 529 11.03 Mlig455_006526

Neo: -

Age: logFC(26M/2M)=-0.435

 ARMC3 1.757 - - - - 0.963 0.794 Mlig455_006526 {REF} {Length: 3183} {TRANSSPLICED} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=100.6]; Ethylene-responsive protein kinase Le-CTR1 [PF14381.8, score=95.8]; HEAT repeats [PF13646.8, score=73.0]; HEAT repeat [PF02985.24, score=53.9]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=42.3]; HEAT-like repeat [PF13513.8, score=42.2]; V-ATPase subunit H [PF11698.10, score=40.9]; Armadillo-like [PF04826.15, score=28.2]; Adaptin N terminal region [PF01602.22, score=21.9]; Interferon-related developmental regulator (IFRD) [PF05004.15, score=18.7]} {Human: ENSG00000165309, ARMC3, armadillo repeat containing 3, [Score=526, Expect=3e-173]} {Mouse: ENSMUSG00000037683, Armc3, armadillo repeat containing 3, [RH, Score=492, Expect=4e-160]} {Dmel: FBgn0033794, CG13326, [Score=55.5, Expect=2e-07]} {Smed: dd_Smed_v6_9679_0_1, dd_Smed_v6_9679_0_1, [RH, Score=743, Expect=0.0]} {RNA1509_9668} {RNA1310_4998.1, RNA1509_9668} {RNA1509_9668, RNA815_8459}
59. MligTC455_52033 531 11.05 Mlig455_050626

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.538

Region-enriched R2: 1.855/0.01555

 PPIL6 1.756 - - 0.956 - 0.800 - Mlig455_050626 {REF} {Length: 1572} {TRANSSPLICED} {Pfam: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD [PF00160.23, score=143.3]} {Human: ENSG00000185250, PPIL6, peptidylprolyl isomerase like 6, [RH, Score=278, Expect=2e-92]} {Mouse: ENSMUSG00000078451, Ppil6, peptidylprolyl isomerase (cyclophilin)-like 6, [RH, Score=266, Expect=4e-88]} {Dmel: FBgn0036415, CG7768, [Score=160, Expect=1e-48]} {Celegans: WBGene00000883, cyn-7, Peptidyl-prolyl cis-trans isomerase 7, [Score=181, Expect=1e-56]} {Smed: dd_Smed_v6_10327_0_1, dd_Smed_v6_10327_0_1, [RH, Score=205, Expect=1e-66]} {RNA1509_5736} {RNA1310_29201} {RNA815_16054}
60. MligTC455_24438 158 3.3 Mlig455_003021

Neo: -

Age: -

 1.755 - - 0.964 0.791 - - Mlig455_003021 {REF} {Length: 3818} {RNA1509_26898} {RNA1310_26663.1} {RNA815_11574}
61. MligTC455_34846 173 3.61 Mlig455_019966, Mlig455_038084

Neo: -

Age: logFC(26M/2M)=0.242

 RPS7 1.755 - - 0.979 - - 0.776

Mlig455_019966 {REF} {Length: 859} {TRANSSPLICED} {Pfam: Ribosomal protein S7e [PF01251.20, score=252.0]} {Human: ENSG00000171863, RPS7, ribosomal protein S7, [Score=244, Expect=4e-81]} {Mouse: ENSMUSG00000061477, Rps7, ribosomal protein S7, [Score=244, Expect=2e-81]; ENSMUSG00000044424, Gm9493, predicted gene 9493, [Score=243, Expect=3e-81]} {Dmel: FBgn0039757, RpS7, Ribosomal protein S7, [Score=226, Expect=2e-74]} {Celegans: WBGene00004476, rps-7, 40S ribosomal protein S7, [Score=201, Expect=7e-65]} {Smed: dd_Smed_v6_204_0_1, dd_Smed_v6_204_0_1, [Score=207, Expect=1e-67]} {RNA1509_856} {RNA1310_42140} {RNA815_20536}

Mlig455_038084 {REF} {Length: 994} {TRANSSPLICED} {Pfam: Ribosomal protein S7e [PF01251.20, score=251.5]} {Human: ENSG00000171863, RPS7, ribosomal protein S7, [RH, Score=244, Expect=9e-81]} {Mouse: ENSMUSG00000044424, Gm9493, predicted gene 9493, [RH, Score=244, Expect=7e-81]; ENSMUSG00000061477, Rps7, ribosomal protein S7, [RH, Score=244, Expect=6e-81]} {Dmel: FBgn0039757, RpS7, Ribosomal protein S7, [Score=226, Expect=5e-74]} {Celegans: WBGene00004476, rps-7, 40S ribosomal protein S7, [Score=201, Expect=3e-64]} {Smed: dd_Smed_v6_204_0_1, dd_Smed_v6_204_0_1, [Score=207, Expect=5e-67]} {RNA1509_1986} {RNA1310_42140} {RNA815_20536}
62. MligTC455_42640 68 1.41 Mlig455_030092

Neo: -

Age: -

 1.754 - - 0.952 0.802 - - Mlig455_030092 {REF} {Length: 1027} {RNA1509_8614} {RNA1310_11540} {RNA815_3767}
63. MligTC455_26164 170 3.54 Mlig455_013776

Neo: -

Age: -

 1.751 - - 0.973 - - 0.778 Mlig455_013776 {REF} {Length: 1666} {RNA1509_56028} {RNA1310_25129} {RNA815_10685.1}
64. MligTC455_37047 45 0.94 Mlig455_046180

Neo: -

Age: -

 1.749 - - - 0.787 0.962 - Mlig455_046180 {REF} {Length: 1686} {RNA1310_140241} {RNA815_12716}
65. MligTC455_41140 58 1.21 Mlig455_031451

Neo: -

Age: logFC(26M/2M)=-0.773

Region-enriched R4: 4.458/0.03971

 SLC6A3 1.745 - - 0.965 - - 0.780 Mlig455_031451 {REF} {Length: 2793} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=534.0]} {Human: ENSG00000276996, SLC6A3, solute carrier family 6 member 3, [Score=451, Expect=2e-150]; ENSG00000142319, SLC6A3, solute carrier family 6 member 3, [Score=451, Expect=2e-150]; ENSG00000103546, SLC6A2, solute carrier family 6 member 2, [Score=439, Expect=4e-146]} {Mouse: ENSMUSG00000021609, Slc6a3, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3, [Score=451, Expect=5e-151]; ENSMUSG00000055368, Slc6a2, solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2, [Score=444, Expect=4e-148]} {Dmel: FBgn0010414, SerT, Serotonin transporter, [Score=421, Expect=5e-139]} {Celegans: WBGene00003387, mod-5, Transporter, [Score=372, Expect=1e-119]} {Smed: dd_Smed_v6_22486_0_1, dd_Smed_v6_22486_0_1, [Score=496, Expect=2e-168]} {RNA1509_9639} {RNA1310_4480.1} {RNA815_1493}
66. MligTC455_19251 284 5.92 Mlig455_051034

Neo: -

Age: -

 RAC1 1.742 - - 0.975 0.767 - - Mlig455_051034 {REF} {Length: 1753} {Pfam: Ras family [PF00071.24, score=151.9]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=63.6]; ADP-ribosylation factor family [PF00025.23, score=23.3]} {Human: ENSG00000136238, RAC1, Rac family small GTPase 1, [Score=208, Expect=3e-68]; ENSG00000169750, RAC3, Rac family small GTPase 3, [Score=203, Expect=3e-66]; ENSG00000128340, RAC2, Rac family small GTPase 2, [Score=201, Expect=3e-65]; ENSG00000177105, RHOG, ras homolog family member G, [Score=200, Expect=4e-65]} {Mouse: ENSMUSG00000001847, Rac1, Rac family small GTPase 1, [Score=208, Expect=2e-68]; ENSMUSG00000018012, Rac3, Rac family small GTPase 3, [Score=203, Expect=2e-66]; ENSMUSG00000073982, Rhog, ras homolog family member G, [Score=200, Expect=3e-65]; ENSMUSG00000033220, Rac2, Rac family small GTPase 2, [Score=199, Expect=4e-65]} {Dmel: FBgn0010333, Rac1, [Score=205, Expect=3e-67]} {Celegans: WBGene00000424, ced-10, Ras-related protein ced-10, [Score=211, Expect=9e-70]} {Smed: dd_Smed_v6_610_0_1, dd_Smed_v6_610_0_1, [Score=199, Expect=3e-65]} {RNA1310_32838}
67. MligTC455_19842 93 1.95 Mlig455_039673

Neo: -

Age: Up-Down-Up

 GRIK2 1.74 - - 0.981 - 0.759 - Mlig455_039673 {REF} {Length: 3561} {Pfam: Ligand-gated ion channel [PF00060.28, score=141.6]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=63.2]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=61.6]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=327, Expect=7e-97]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=322, Expect=1e-94]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=327, Expect=8e-97]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=322, Expect=1e-94]} {Dmel: FBgn0038837, CG3822, [Score=320, Expect=1e-94]} {Celegans: WBGene00001615, glr-4, GLutamate Receptor family (AMPA), [Score=299, Expect=2e-86]} {Smed: dd_Smed_v6_14655_0_1, dd_Smed_v6_14655_0_1, [Score=392, Expect=3e-120]} {RNA1509_45189} {RNA1310_13827.1} {RNA815_34006}
68. MligTC455_40833 1043 21.73 Mlig455_000178

Neo: -

Age: logFC(26M/2M)=-0.724

 1.739 - - - - 0.958 0.781 Mlig455_000178 {REF} {Length: 1419} {Smed: dd_Smed_v6_10173_0_1, dd_Smed_v6_10173_0_1, [Score=51.2, Expect=1e-07]} {RNA1509_23138} {RNA1310_23456.1} {RNA815_37333}
69. MligTC455_52923 144 2.99 Mlig455_039520, Mlig455_051311

Neo: -

Age: -

 1.737 - - 0.958 - - 0.779

Mlig455_039520 {REF} {Length: 1240} {RNA1509_39289} {RNA1310_98847} {RNA815_64330}

Mlig455_051311 {REF} {Length: 457} {NoTransDecoderORF} {RNA1310_93796} {RNA815_64330}
70. MligTC455_30984 72 1.51 Mlig455_045664

Neo: -

Age: logFC(26M/2M)=-0.318

Region-enriched R4: 4.894/0.00976

 VDAC2 1.736 - - 0.987 - - 0.749 Mlig455_045664 {REF} {Length: 3932} {TRANSSPLICED} {Pfam: Eukaryotic porin [PF01459.24, score=212.5]; TATA element modulatory factor 1 TATA binding [PF12325.10, score=19.5]} {Human: ENSG00000165637, VDAC2, voltage dependent anion channel 2, [RH, Score=275, Expect=4e-85]; ENSG00000213585, VDAC1, voltage dependent anion channel 1, [RH, Score=265, Expect=2e-81]} {Mouse: ENSMUSG00000021771, Vdac2, voltage-dependent anion channel 2, [RH, Score=277, Expect=7e-86]; ENSMUSG00000020402, Vdac1, voltage-dependent anion channel 1, [RH, Score=268, Expect=2e-82]} {Dmel: FBgn0004363, porin, [RH, Score=255, Expect=5e-78]} {Celegans: WBGene00019900, vdac-1, Probable voltage-dependent anion-selective channel, [Score=159, Expect=1e-43]} {Smed: dd_Smed_v6_2119_0_1, dd_Smed_v6_2119_0_1, [RH, Score=206, Expect=5e-60]} {RNA1509_26410, RNA1509_9326} {RNA1310_13038, RNA1509_26410, RNA1509_9326} {RNA1509_26410, RNA1509_9326, RNA815_4253}
71. MligTC455_54164 484 10.08 Mlig455_066681

Neo: -

Age: logFC(26M/2M)=0.269

 ALG11 1.73 - - 0.974 - - 0.756 Mlig455_066681 {REF} {Length: 3805} {TRANSSPLICED} {Pfam: ALG11 mannosyltransferase N-terminus [PF15924.7, score=213.1]; Glycosyl transferases group 1 [PF00534.22, score=88.2]; Glycosyl transferases group 1 [PF13692.8, score=47.4]} {Human: ENSG00000253710, ALG11, ALG11, alpha-1,2-mannosyltransferase, [RH, Score=348, Expect=4e-114]} {Mouse: ENSMUSG00000063362, Alg11, asparagine-linked glycosylation 11 (alpha-1,2-mannosyltransferase), [RH, Score=336, Expect=6e-110]} {Dmel: FBgn0037108, CG11306, [Score=326, Expect=3e-106]} {Celegans: WBGene00015162, algn-11, GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase, [Score=260, Expect=4e-81]} {Smed: dd_Smed_v6_6817_0_1, dd_Smed_v6_6817_0_1, [RH, Score=295, Expect=1e-94]} {RNA1509_50483, RNA1509_7550} {RNA1310_18644.1, RNA1509_50483} {RNA1509_50483, RNA815_14948}
72. MligTC455_13842 147 3.06 Mlig455_050519, Mlig455_050534

Neo: -

Age: -

 1.727 - - - 0.771 0.956 -

Mlig455_050519 {REF} {Length: 3305} {Pfam: Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=48.2]; 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=46.7]} {Dmel: FBgn0034168, CG15614, [RH, Score=70.5, Expect=7e-13]} {Celegans: WBGene00015263, B0563.6, Probable G-protein coupled receptor B0563.6, [Score=65.1, Expect=3e-11]} {Smed: dd_Smed_v6_11997_0_1, dd_Smed_v6_11997_0_1, [RH, Score=152, Expect=7e-42]} {RNA1310_19665} {RNA815_26737}

Mlig455_050534 {REF} {Length: 3633} {Pfam: Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=48.2]; 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=46.7]} {Dmel: FBgn0034168, CG15614, [RH, Score=70.5, Expect=7e-13]} {Celegans: WBGene00015263, B0563.6, Probable G-protein coupled receptor B0563.6, [Score=65.1, Expect=3e-11]} {Smed: dd_Smed_v6_11997_0_1, dd_Smed_v6_11997_0_1, [RH, Score=152, Expect=7e-42]} {RNA1310_19665} {RNA815_26737}
73. MligTC455_33478 208 4.33 Mlig455_022409

Neo: -

Age: -

 NWD2 1.724 - - 0.973 - 0.751 - Mlig455_022409 {REF} {Length: 6827} {TRANSSPLICED} {Pfam: NACHT domain [PF05729.14, score=46.0]; Domain of unknown function (DUF4062) [PF13271.8, score=39.7]; Dpy-30 motif [PF05186.15, score=38.1]; AAA domain [PF13401.8, score=36.3]; AAA ATPase domain [PF13191.8, score=31.8]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=363, Expect=5e-101]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [Score=362, Expect=8e-101]} {Dmel: FBgn0038397, CG10185, [Score=514, Expect=1e-151]} {Celegans: WBGene00020254, T05C3.2, [Score=507, Expect=6e-149]} {Smed: dd_Smed_v6_11085_0_1, dd_Smed_v6_11085_0_1, [Score=291, Expect=4e-79]} {RNA1509_23610} {RNA1310_451.1, RNA1509_23610} {RNA1509_23610, RNA815_2750}
74. MligTC455_46793 652 13.58 Mlig455_058553

Neo: -

Age: -

 SYTL4 1.724 - - 0.771 - 0.953 - Mlig455_058553 {REF} {Length: 2601} {TRANSSPLICED} {Pfam: C2 domain [PF00168.32, score=103.1]} {Human: ENSG00000102362, SYTL4, synaptotagmin like 4, [Score=153, Expect=2e-38]; ENSG00000147041, SYTL5, synaptotagmin like 5, [Score=150, Expect=2e-37]; ENSG00000142765, SYTL1, synaptotagmin like 1, [Score=149, Expect=1e-37]} {Mouse: ENSMUSG00000031255, Sytl4, synaptotagmin-like 4, [Score=160, Expect=6e-41]} {Dmel: FBgn0266756, btsz, bitesize, [Score=193, Expect=2e-51]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=86.3, Expect=1e-17]} {Smed: dd_Smed_v6_10375_0_1, dd_Smed_v6_10375_0_1, [RH, Score=157, Expect=3e-40]} {RNA1509_50455} {RNA1310_5507.1, RNA1509_50455} {RNA1509_50455, RNA815_17811}
75. MligTC455_29192 53 1.11 Mlig455_016518

Neo: -

Age: -

 1.723 - - 0.969 - 0.754 - Mlig455_016518 {REF} {Length: 5343} {Pfam: Procyclic acidic repetitive protein (PARP) [PF05887.13, score=21.0]} {Dmel: FBgn0029807, CG3108, [Score=57.4, Expect=1e-09]} {RNA1509_9867} {RNA1310_554.1} {RNA815_212.1}
76. MligTC455_46340 259 5.4 Mlig455_049774

Neo: -

Age: -

Region-enriched R1: 5.320/0.00375

 1.723 - - - 0.755 0.968 - Mlig455_049774 {REF} {Length: 1638} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=40.1]; Ankyrin repeats (many copies) [PF13637.8, score=27.8]; Ankyrin repeats (many copies) [PF13857.8, score=24.8]; Ankyrin repeat [PF13606.8, score=19.1]} {Smed: dd_Smed_v6_29956_0_1, dd_Smed_v6_29956_0_1, [RH, Score=75.9, Expect=1e-14]} {RNA1509_39973} {RNA1310_21889} {RNA815_13094}
77. MligTC455_18890 42 0.87 Mlig455_013800

Neo: -

Age: Up-Down-Down

 1.722 - - 0.968 0.754 - - Mlig455_013800 {REF} {Length: 1234} {RNA1509_44733} {RNA1310_35976} {RNA815_45308}
78. MligTC455_17161 305 6.35 Mlig455_005978

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.869

 FAM20B 1.72 - - 0.971 - - 0.749 Mlig455_005978 {REF} {Length: 2922} {TRANSSPLICED} {Pfam: Golgi casein kinase, C-terminal, Fam20 [PF06702.14, score=172.6]; Ribosomal protein L6e [PF01159.21, score=113.2]; Ribosomal protein L6, N-terminal domain [PF03868.17, score=21.8]} {Human: ENSG00000116199, FAM20B, FAM20B, glycosaminoglycan xylosylkinase, [RH, Score=224, Expect=1e-65]} {Mouse: ENSMUSG00000033557, Fam20b, family with sequence similarity 20, member B, [RH, Score=219, Expect=8e-64]} {Dmel: FBgn0039857, RpL6, Ribosomal protein L6, [RH, Score=211, Expect=6e-63]} {Celegans: WBGene00010356, H03A11.1, Extracellular serine/threonine protein kinase CeFam20, [RH, Score=153, Expect=1e-39]} {Smed: dd_Smed_v6_839_0_1, dd_Smed_v6_839_0_1, [RH, Score=170, Expect=1e-47]} {RNA1509_31893} {RNA1310_20853} {RNA815_8370}
79. MligTC455_26581 71 1.48 Mlig455_013862

Neo: -

Age: -

 ALKBH3 1.72 - - 0.955 0.765 - - Mlig455_013862 {REF} {Length: 4239} {TRANSSPLICED} {Pfam: WSC domain [PF01822.21, score=158.2]; 2OG-Fe(II) oxygenase superfamily [PF13532.8, score=89.5]} {Human: ENSG00000166199, ALKBH3, alkB homolog 3, alpha-ketoglutaratedependent dioxygenase, [Score=117, Expect=2e-28]} {Mouse: ENSMUSG00000040174, Alkbh3, alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase, [Score=115, Expect=6e-28]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=51.2, Expect=5e-06]} {Smed: dd_Smed_v6_7441_0_1, dd_Smed_v6_7441_0_1, [Score=105, Expect=2e-24]} {RNA1509_29984} {RNA1310_8204} {RNA815_38513}
80. MligTC455_31061 233 4.86 Mlig455_057963

Neo: -

Age: -

Region-enriched R4: 2.384/0.00974

 TONSL 1.718 - - 0.960 0.758 - - Mlig455_057963 {REF} {Length: 5732} {Pfam: Leucine Rich repeat [PF13516.8, score=32.3]; Leucine Rich repeats (2 copies) [PF12799.9, score=24.7]} {Human: ENSG00000160949, TONSL, tonsoku like, DNA repair protein, [Score=53.9, Expect=1e-06]; ENSG00000285453, TONSL, tonsoku like, DNA repair protein, [Score=53.9, Expect=1e-06]} {RNA1509_54268} {RNA1310_1677.2} {RNA815_2688}
81. MligTC455_13319 161 3.36 Mlig455_037764

Neo: -

Age: -

 1.717 - - 0.956 - 0.761 - Mlig455_037764 {REF} {Length: 3362} {Smed: dd_Smed_v6_7428_0_1, dd_Smed_v6_7428_0_1, [RH, Score=91.7, Expect=6e-19]} {RNA1509_12918} {RNA1310_7526.1, RNA1509_12918} {RNA1509_12918, RNA815_9598.1}
82. MligTC455_47216 803 16.72 Mlig455_052798

Neo: -

Age: -

 1.716 - - - 0.742 0.974 - Mlig455_052798 {REF} {Length: 4690} {TRANSSPLICED} {Pfam: Arginine/serine-rich protein PNISR [PF15996.7, score=44.6]} {RNA1509_22491} {RNA1310_7215.1, RNA1509_22491} {RNA1509_22491, RNA815_6578.1}
83. MligTC455_42737 186 3.87 Mlig455_034935

Neo: -

Age: Up-Down-Down

 EGFLAM 1.715 - - 0.974 - 0.741 - Mlig455_034935 {REF} {Length: 6718} {Pfam: Laminin G domain [PF02210.26, score=150.7]; Laminin G domain [PF00054.25, score=144.6]; Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=36.8]; EGF-like domain [PF00008.29, score=22.4]} {Human: ENSG00000164318, EGFLAM, EGF like, fibronectin type III and laminin G domains, [Score=210, Expect=2e-56]} {Mouse: ENSMUSG00000042961, Egflam, EGF-like, fibronectin type III and laminin G domains, [Score=208, Expect=4e-56]} {Dmel: FBgn0034070, SP2353, [Score=183, Expect=1e-47]} {Celegans: WBGene00020581, T19D12.6, [RH, Score=68.6, Expect=1e-11]} {Smed: dd_Smed_v6_10946_0_2, dd_Smed_v6_10946_0_2, [Score=224, Expect=1e-62]} {RNA1509_25168} {RNA1310_18750.2} {RNA815_19872}
84. MligTC455_25582 465 9.69 Mlig455_009721

Neo: -

Age: Up-Down-Down

Region-enriched R2: 1.797/0.02183

 CHRNA3 1.714 - - 0.974 - 0.740 - Mlig455_009721 {REF} {Length: 2022} {TRANSSPLICED} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=280.9]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=264.3]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [RH, Score=455, Expect=3e-155]; ENSG00000117971, CHRNB4, cholinergic receptor nicotinic beta 4 subunit, [RH, Score=452, Expect=3e-154]; ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [RH, Score=450, Expect=3e-153]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [RH, Score=445, Expect=2e-151]; ENSG00000101204, CHRNA4, cholinergic receptor nicotinic alpha 4 subunit, [RH, Score=443, Expect=6e-149]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [RH, Score=456, Expect=8e-156]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [RH, Score=446, Expect=6e-152]; ENSMUSG00000035200, Chrnb4, cholinergic receptor, nicotinic, beta polypeptide 4, [RH, Score=439, Expect=2e-149]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [RH, Score=600, Expect=0.0]} {Celegans: WBGene00006797, unc-63, Acetylcholine receptor subunit alpha-type unc-63, [RH, Score=506, Expect=1e-175]} {Smed: dd_Smed_v6_14630_0_1, dd_Smed_v6_14630_0_1, [Score=468, Expect=7e-160]} {RNA1509_19239} {RNA1310_7228, RNA1509_19239} {RNA1509_19239, RNA815_134.1}
85. MligTC455_24900 764 15.91 Mlig455_042657, Mlig455_042690

Neo: -

Age: -

 PLCB4 1.713 - - 0.978 - 0.735 -

Mlig455_042657 {REF} {Length: 6508} {TRANSSPLICED} {Pfam: Phosphatidylinositol-specific phospholipase C, X domain [PF00388.21, score=199.3]; Phosphatidylinositol-specific phospholipase C, Y domain [PF00387.21, score=138.6]; PH domain [PF17787.3, score=109.2]; Protein of unknown function (DUF1154) [PF06631.13, score=47.4]; Phosphoinositide-specific phospholipase C, efhand-like [PF09279.13, score=41.7]; C2 domain [PF00168.32, score=22.8]} {Human: ENSG00000101333, PLCB4, phospholipase C beta 4, [RH, Score=1296, Expect=0.0]} {Mouse: ENSMUSG00000039943, Plcb4, phospholipase C, beta 4, [RH, Score=1170, Expect=0.0]} {Dmel: FBgn0262738, norpA, no receptor potential A, [RH, Score=565, Expect=4e-180]} {Celegans: WBGene00001177, egl-8, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8, [RH, Score=1127, Expect=0.0]} {Smed: dd_Smed_v6_3221_0_1, dd_Smed_v6_3221_0_1, [RH, Score=1510, Expect=0.0]} {RNA1509_3820} {RNA1310_563.1} {RNA815_911.1}

Mlig455_042690 {REF} {Length: 550} {TRANSSPLICED} {Pfam: PH domain [PF17787.3, score=62.8]} {Human: ENSG00000101333, PLCB4, phospholipase C beta 4, [RH, Score=89.0, Expect=6e-24]} {Mouse: ENSMUSG00000039943, Plcb4, phospholipase C, beta 4, [Score=88.6, Expect=4e-21]} {Dmel: FBgn0262738, norpA, no receptor potential A, [Score=80.9, Expect=1e-18]} {Celegans: WBGene00001177, egl-8, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8, [Score=73.9, Expect=2e-16]} {Smed: dd_Smed_v6_3221_0_1, dd_Smed_v6_3221_0_1, [Score=144, Expect=6e-41]} {RNA1509_48109} {RNA1310_563.1} {RNA815_18946.1}
86. MligTC455_31872 115 2.4 Mlig455_031280

Neo: -

Age: -

 1.713 - - 0.965 - 0.748 - Mlig455_031280 {REF} {Length: 4437} {RNA1509_44223} {RNA1310_53789} {RNA815_61017}
87. MligTC455_27897 128 2.66 Mlig455_012952, Mlig455_012961

Neo: -

Age: -

 1.711 - - 0.970 - 0.741 -

Mlig455_012952 {REF} {Length: 2131} {Pfam: Protein of unknown function (DUF1180) [PF06679.14, score=20.2]; Family of unknown function (DUF6491) [PF20101.1, score=18.6]} {RNA1509_2412} {RNA1310_41742} {RNA815_21822}

Mlig455_012961 {REF} {Length: 2277} {Pfam: Protein of unknown function (DUF1180) [PF06679.14, score=20.2]; Family of unknown function (DUF6491) [PF20101.1, score=19.4]} {RNA1509_2412} {RNA1310_41742} {RNA815_21822}
88. MligTC455_17914 199 4.14 Mlig455_029637

Neo: -

Age: -

 AP2M1 1.71 - - 0.951 - 0.759 - Mlig455_029637 {REF} {Length: 3242} {TRANSSPLICED} {Pfam: Adaptor complexes medium subunit family [PF00928.23, score=265.9]; Clathrin adaptor complex small chain [PF01217.22, score=24.7]} {Human: ENSG00000161203, AP2M1, adaptor related protein complex 2 subunit mu 1, [RH, Score=754, Expect=0.0]} {Mouse: ENSMUSG00000022841, Ap2m1, adaptor-related protein complex 2, mu 1 subunit, [RH, Score=754, Expect=0.0]} {Dmel: FBgn0263351, AP-2mu, Adaptor Protein complex 2, mu subunit, [RH, Score=750, Expect=0.0]} {Celegans: WBGene00001082, dpy-23, AP-2 complex subunit mu, [RH, Score=723, Expect=0.0]} {Smed: dd_Smed_v6_1271_0_1, dd_Smed_v6_1271_0_1, [RH, Score=732, Expect=0.0]} {RNA1509_24209} {RNA1310_15131.1} {RNA815_3295.1}
89. MligTC455_43034 470 9.79 Mlig455_009703

Neo: -

Age: -

 1.709 - - 0.975 - - 0.734 Mlig455_009703 {REF} {Length: 4741} {Pfam: NHL repeat [PF01436.23, score=34.6]} {Dmel: FBgn0265356, tn, thin, [Score=53.9, Expect=2e-07]} {RNA1509_22989} {RNA1310_8201.1, RNA1509_22989} {RNA1509_22989, RNA815_27967}
90. MligTC455_42648 99 2.06 Mlig455_044446

Neo: -

Age: Down-Up-Down

 MEIS1 1.708 - - 0.957 - - 0.751 Mlig455_044446 {REF} {Length: 3616} {Pfam: N-terminal of Homeobox Meis and PKNOX1 [PF16493.7, score=134.9]; Homeobox KN domain [PF05920.13, score=71.0]; Homeodomain [PF00046.31, score=32.6]} {Human: ENSG00000143995, MEIS1, Meis homeobox 1, [RH, Score=191, Expect=3e-53]; ENSG00000134138, MEIS2, Meis homeobox 2, [RH, Score=191, Expect=3e-53]} {Mouse: ENSMUSG00000027210, Meis2, Meis homeobox 2, [RH, Score=191, Expect=3e-53]; ENSMUSG00000020160, Meis1, Meis homeobox 1, [RH, Score=191, Expect=3e-53]} {Dmel: FBgn0001235, hth, homothorax, [Score=176, Expect=2e-50]} {Celegans: WBGene00006796, unc-62, Homeobox protein unc-62, [RH, Score=170, Expect=2e-45]} {Smed: dd_Smed_v6_6114_0_2, dd_Smed_v6_6114_0_2, [RH, Score=226, Expect=9e-66]} {RNA1509_22853} {RNA1310_27014, RNA1509_22853} {RNA1509_22853, RNA815_28484}
91. MligTC455_20719 173 3.61 Mlig455_034915

Neo: -

Age: -

 SKIL 1.704 - - 0.963 - 0.741 - Mlig455_034915 {REF} {Length: 4545} {Pfam: SKI/SNO/DAC family [PF02437.19, score=103.5]; c-SKI Smad4 binding domain [PF08782.12, score=103.1]} {Human: ENSG00000136603, SKIL, SKI like proto-oncogene, [RH, Score=197, Expect=1e-53]; ENSG00000157933, SKI, SKI proto-oncogene, [RH, Score=192, Expect=2e-51]} {Mouse: ENSMUSG00000027660, Skil, SKI-like, [RH, Score=197, Expect=6e-54]; ENSMUSG00000029050, Ski, ski sarcoma viral oncogene homolog (avian), [RH, Score=194, Expect=1e-52]} {Dmel: FBgn0085450, Snoo, Sno oncogene, [RH, Score=183, Expect=4e-48]} {Smed: dd_Smed_v6_10921_0_1, dd_Smed_v6_10921_0_1, [RH, Score=153, Expect=8e-40]} {RNA1509_57419} {RNA1310_5927, RNA1509_57419} {RNA1509_57419, RNA815_17262}
92. MligTC455_18386 230 4.8 Mlig455_029645

Neo: -

Age: -

 DLG1 1.702 - - 0.950 - 0.752 - Mlig455_029645 {REF} {Length: 2388} {Pfam: PDZ domain [PF00595.26, score=135.7]; L27_1 [PF09058.12, score=96.1]; PDZ domain [PF17820.3, score=55.3]; PDZ domain [PF13180.8, score=32.3]} {Human: ENSG00000075711, DLG1, discs large MAGUK scaffold protein 1, [Score=259, Expect=2e-77]} {Mouse: ENSMUSG00000022770, Dlg1, discs large MAGUK scaffold protein 1, [Score=259, Expect=4e-80]} {Dmel: FBgn0001624, dlg1, discs large 1, [Score=249, Expect=9e-74]} {Celegans: WBGene00001006, dlg-1, Drosophila Discs LarGe homolog; MAGUK protein DLG-1; SAP97-like protein DLG-1, [Score=128, Expect=1e-31]} {Smed: dd_Smed_v6_3493_1_1, dd_Smed_v6_3493_1_1, [Score=130, Expect=2e-33]} {RNA1509_30464} {RNA1310_16239, RNA1509_30464} {RNA1509_30464, RNA815_16951}
93. MligTC455_52109 297 6.19 Mlig455_069072

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.347

 1.7 0.738 - 0.962 - - - Mlig455_069072 {REF} {Length: 2302} {RNA1509_46495} {RNA1310_32026} {RNA815_11216.2}
94. MligTC455_37051 372 7.75 Mlig455_036602, Mlig455_036642

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.299

 DNAH7 1.699 - - 0.972 0.727 - -

Mlig455_036602 {REF} {Length: 11684} {TRANSSPLICED} {Pfam: Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=514.7]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=397.8]; P-loop containing dynein motor region [PF12775.9, score=249.2]; Dynein heavy chain AAA lid domain [PF17852.3, score=89.9]; AAA domain (dynein-related subfamily) [PF07728.16, score=55.6]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=29.8]; AAA domain [PF13401.8, score=22.7]; RNA helicase [PF00910.24, score=22.3]; AAA ATPase domain [PF13191.8, score=20.1]} {Human: ENSG00000118997, DNAH7, dynein axonemal heavy chain 7, [Score=1815, Expect=0.0]} {Mouse: ENSMUSG00000096141, Dnah7a, dynein, axonemal, heavy chain 7A, [Score=1810, Expect=0.0]; ENSMUSG00000101337, Dnah7c, dynein, axonemal, heavy chain 7C, [Score=1807, Expect=0.0]; ENSMUSG00000041144, Dnah7b, dynein, axonemal, heavy chain 7B, [Score=1800, Expect=0.0]} {Dmel: FBgn0013810, Dhc36C, Dynein heavy chain at 36C, [Score=1600, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=625, Expect=0.0]} {Smed: dd_Smed_v6_10846_0_1, dd_Smed_v6_10846_0_1, [Score=1468, Expect=0.0]} {RNA1509_8248} {RNA1310_99} {RNA815_595}

Mlig455_036642 {REF} {Length: 12783} {TRANSSPLICED} {Pfam: Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=511.4]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=488.0]; Dynein heavy chain C-terminal domain [PF18199.3, score=380.3]; P-loop containing dynein motor region D4 [PF12780.9, score=368.2]; ATP-binding dynein motor region [PF12781.9, score=319.5]; P-loop containing dynein motor region [PF12775.9, score=278.9]; Dynein heavy chain AAA lid domain [PF18198.3, score=202.7]; Microtubule-binding stalk of dynein motor [PF12777.9, score=184.2]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=154.9]; Dynein heavy chain AAA lid domain [PF17852.3, score=107.4]; AAA+ lid domain [PF17857.3, score=72.9]; AAA domain (dynein-related subfamily) [PF07728.16, score=63.5]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=31.7]; AAA domain [PF13401.8, score=29.0]; AAA ATPase domain [PF13191.8, score=21.8]} {Human: ENSG00000118997, DNAH7, dynein axonemal heavy chain 7, [Score=5221, Expect=0.0]} {Mouse: ENSMUSG00000101337, Dnah7c, dynein, axonemal, heavy chain 7C, [Score=5215, Expect=0.0]; ENSMUSG00000041144, Dnah7b, dynein, axonemal, heavy chain 7B, [Score=5209, Expect=0.0]; ENSMUSG00000096141, Dnah7a, dynein, axonemal, heavy chain 7A, [Score=5197, Expect=0.0]} {Dmel: FBgn0013810, Dhc36C, Dynein heavy chain at 36C, [RH, Score=4322, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=709, Expect=0.0]} {Smed: dd_Smed_v6_5350_0_1, dd_Smed_v6_5350_0_1, [RH, Score=4284, Expect=0.0]} {RNA1509_8248} {RNA1310_99} {RNA815_595}
95. MligTC455_06458 109 2.27 Mlig455_058915

Neo: -

Age: -

 TMEM184B 1.698 - - 0.956 0.742 - - Mlig455_058915 {REF} {Length: 2946} {Pfam: Organic solute transporter Ostalpha [PF03619.18, score=289.5]} {Human: ENSG00000198792, TMEM184B, transmembrane protein 184B, [RH, Score=437, Expect=5e-152]} {Mouse: ENSMUSG00000009035, Tmem184b, transmembrane protein 184b, [RH, Score=432, Expect=5e-150]} {Dmel: FBgn0035236, CG12004, [RH, Score=446, Expect=2e-154]} {Celegans: WBGene00009574, F40E10.6, [RH, Score=473, Expect=2e-166]} {Smed: dd_Smed_v6_3881_1_1, dd_Smed_v6_3881_1_1, [RH, Score=461, Expect=2e-162]} {RNA1310_13503.1} {RNA815_394.1}
96. MligTC455_39645 162 3.37 Mlig455_020209

Neo: -

Age: -

 SCNN1B 1.696 - - 0.977 - 0.719 - Mlig455_020209 {REF} {Length: 3023} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=191.2]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=62.0, Expect=3e-09]} {Mouse: ENSMUSG00000030873, Scnn1b, sodium channel, nonvoltage-gated 1 beta, [Score=51.6, Expect=3e-06]; ENSMUSG00000000216, Scnn1g, sodium channel, nonvoltage-gated 1 gamma, [Score=50.8, Expect=6e-06]} {Celegans: WBGene00006832, unc-105, Degenerin-like protein unc-105, [Score=89.4, Expect=4e-18]} {Smed: dd_Smed_v6_22997_0_1, dd_Smed_v6_22997_0_1, [RH, Score=359, Expect=1e-114]} {RNA1509_55954} {RNA1310_12497, RNA1509_55954} {RNA1509_55954, RNA815_17110}
97. MligTC455_53257 187 3.9 Mlig455_018115

Neo: -

Age: -

 BSG 1.693 - - 0.967 - - 0.726 Mlig455_018115 {REF} {Length: 2576} {Pfam: Immunoglobulin domain [PF13927.8, score=32.6]; Immunoglobulin I-set domain [PF07679.18, score=26.7]; Immunoglobulin domain [PF13895.8, score=25.2]; Immunoglobulin domain [PF00047.27, score=20.7]} {Human: ENSG00000172270, BSG, basigin (Ok blood group), [Score=50.1, Expect=2e-06]} {Mouse: ENSMUSG00000023175, Bsg, basigin, [Score=55.8, Expect=2e-08]} {RNA1509_32620} {RNA1310_13060.2, RNA1509_32620} {RNA1509_32620, RNA815_13381}
98. MligTC455_30138 465 9.69 Mlig455_038022, Mlig455_068400

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.522

Region-enriched R2: 2.607/0.01918

 HEATR4 1.691 - - - - 0.958 0.733

Mlig455_038022 {REF} {Length: 4854} {TRANSSPLICED} {Pfam: HEAT repeats [PF13646.8, score=77.9]; HEAT repeat [PF02985.24, score=45.7]; HEAT-like repeat [PF13513.8, score=26.2]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=18.9]} {Human: ENSG00000187105, HEATR4, HEAT repeat containing 4, [RH, Score=339, Expect=3e-98]} {Mouse: ENSMUSG00000090843, Heatr4, HEAT repeat containing 4, [RH, Score=327, Expect=8e-95]} {Smed: dd_Smed_v6_16127_0_1, dd_Smed_v6_16127_0_1, [RH, Score=460, Expect=8e-141]} {RNA1509_8516} {RNA1310_8186} {RNA815_1423.1}

Mlig455_068400 {REF} {Length: 4848} {TRANSSPLICED} {Pfam: HEAT repeats [PF13646.8, score=88.8]; HEAT repeat [PF02985.24, score=45.7]; HEAT-like repeat [PF13513.8, score=25.9]} {Human: ENSG00000187105, HEATR4, HEAT repeat containing 4, [RH, Score=340, Expect=1e-98]} {Mouse: ENSMUSG00000090843, Heatr4, HEAT repeat containing 4, [RH, Score=328, Expect=2e-95]} {Smed: dd_Smed_v6_16127_0_1, dd_Smed_v6_16127_0_1, [RH, Score=460, Expect=5e-141]} {RNA1509_8516} {RNA1310_8186} {RNA815_1423.1}
99. MligTC455_20486 272 5.68 Mlig455_003863

Neo: -

Age: -

Region-enriched R4: 1.903/0.03057

 ZC3H4 1.683 - - 0.959 - - 0.724 Mlig455_003863 {REF} {Length: 4091} {TRANSSPLICED} {Pfam: Zinc finger domain [PF18345.3, score=34.1]; Zinc finger C-x8-C-x5-C-x3-H type (and similar) [PF00642.26, score=31.3]; RNA-binding, Nab2-type zinc finger [PF14608.8, score=24.4]} {Human: ENSG00000130749, ZC3H4, zinc finger CCCH-type containing 4, [RH, Score=129, Expect=5e-30]; ENSG00000188177, ZC3H6, zinc finger CCCH-type containing 6, [RH, Score=125, Expect=1e-28]} {Mouse: ENSMUSG00000059273, Zc3h4, zinc finger CCCH-type containing 4, [RH, Score=129, Expect=9e-30]} {Dmel: FBgn0003575, su(sable), suppressor of sable, [RH, Score=77.8, Expect=4e-14]} {Celegans: WBGene00020827, T26A8.4, [RH, Score=84.7, Expect=1e-16]} {Smed: dd_Smed_v6_11872_0_1, dd_Smed_v6_11872_0_1, [RH, Score=94.0, Expect=2e-19]} {RNA1509_24888} {RNA1310_4157, RNA1509_24888} {RNA1509_24888, RNA815_7375.1}
100. MligTC455_31030 130 2.7 Mlig455_063931

Neo: -

Age: -

 RPL17 1.682 - - 0.970 - - 0.712 Mlig455_063931 {REF} {Length: 736} {TRANSSPLICED} {Pfam: Ribosomal protein L22p/L17e [PF00237.21, score=133.8]} {Human: ENSG00000265681, RPL17, ribosomal protein L17, [RH, Score=227, Expect=3e-76]; ENSG00000215472, RPL17-C18orf32, RPL17-C18orf32 readthrough, [RH, Score=226, Expect=7e-76]} {Mouse: ENSMUSG00000062328, Rpl17, ribosomal protein L17, [RH, Score=227, Expect=2e-76]} {Dmel: FBgn0029897, RpL17, Ribosomal protein L17, [Score=225, Expect=9e-76]} {Celegans: WBGene00004429, rpl-17, 60S ribosomal protein L17, [RH, Score=225, Expect=6e-76]} {Smed: dd_Smed_v6_95_0_1, dd_Smed_v6_95_0_1, [RH, Score=229, Expect=2e-77]} {RNA1509_291} {RNA1310_45129} {RNA815_22534}

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