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Results for MligTC455_51779

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_51779 660 13.75 Mlig455_031396

Neo: -

Age: Up-Down-Down

Region-enriched R2: 2.441/0.00016

CACNA1C Mlig455_031396 {REF} {Length: 8157} {Pfam: Ion transport protein [PF00520.33, score=797.6]; Voltage gated calcium channel IQ domain [PF08763.13, score=101.0]; Voltage-dependent L-type calcium channel, IQ-associated [PF16905.7, score=100.3]; Polycystin cation channel [PF08016.14, score=31.5]} {Human: ENSG00000151067, CACNA1C, calcium voltage-gated channel subunit alpha1 C, [Score=1289, Expect=0.0]; ENSG00000285479, CACNA1C, calcium voltage-gated channel subunit alpha1 C, [Score=1289, Expect=0.0]; ENSG00000157388, CACNA1D, calcium voltage-gated channel subunit alpha1 D, [Score=1286, Expect=0.0]; ENSG00000081248, CACNA1S, calcium voltage-gated channel subunit alpha1 S, [Score=1273, Expect=0.0]} {Mouse: ENSMUSG00000051331, Cacna1c, calcium channel, voltage-dependent, L type, alpha 1C subunit, [Score=1294, Expect=0.0]; ENSMUSG00000015968, Cacna1d, calcium channel, voltage-dependent, L type, alpha 1D subunit, [Score=1288, Expect=0.0]; ENSMUSG00000031142, Cacna1f, calcium channel, voltage-dependent, alpha 1F subunit, [Score=1276, Expect=0.0]; ENSMUSG00000026407, Cacna1s, calcium channel, voltage-dependent, L type, alpha 1S subunit, [Score=1260, Expect=0.0]} {Dmel: FBgn0001991, Ca-alpha1D, Ca[2+]-channel protein alpha[[1]] subunit D, [Score=1292, Expect=0.0]} {Celegans: WBGene00006742, unc-2, High voltage activated calcium channel alpha-1 subunit, [RH, Score=1690, Expect=0.0]} {Smed: dd_Smed_v6_13295_0_1, dd_Smed_v6_13295_0_1, [RH, Score=2129, Expect=0.0]} {RNA1509_11510} {RNA1310_2184.1} {RNA815_2606}

Cumulative graph for MligTC455_51779

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.563 3.856 0.57936 1.00000
RegionR2 2.441 3.856 0.00000 0.00016
RegionR3 -0.569 3.856 0.26168 0.80546
RegionR4 0.519 3.856 0.27406 0.58053
RegionR5 -1.447 3.856 0.00255 0.02093
RegionR6 -0.462 3.856 0.37066 0.95095
RegionR7 0.144 3.856 0.81127 1.00000
RegionR8 -1.189 3.856 0.21256 0.81653

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.56 3.856 0.32705 1.00000
RegenerationR2 0.028 3.856 0.95161 1.00000
RegenerationR3 0.769 3.856 0.15554 0.58643
RegenerationR4 -1.613 3.856 0.00185 0.05354
RegenerationR5 0.708 3.856 0.17848 0.60690
RegenerationR6 0.71 3.856 0.19991 0.54046
RegenerationBL 0.684 3.856 0.30984 0.67516
RegenerationTP -0.18 3.856 0.83400 1.00000


Genes with expression patterns similar to MligTC455_51779

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_51779 660 13.75 Mlig455_031396

Neo: -

Age: Up-Down-Down

Region-enriched R2: 2.441/0.00016

CACNA1C 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_031396 {REF} {Length: 8157} {Pfam: Ion transport protein [PF00520.33, score=797.6]; Voltage gated calcium channel IQ domain [PF08763.13, score=101.0]; Voltage-dependent L-type calcium channel, IQ-associated [PF16905.7, score=100.3]; Polycystin cation channel [PF08016.14, score=31.5]} {Human: ENSG00000151067, CACNA1C, calcium voltage-gated channel subunit alpha1 C, [Score=1289, Expect=0.0]; ENSG00000285479, CACNA1C, calcium voltage-gated channel subunit alpha1 C, [Score=1289, Expect=0.0]; ENSG00000157388, CACNA1D, calcium voltage-gated channel subunit alpha1 D, [Score=1286, Expect=0.0]; ENSG00000081248, CACNA1S, calcium voltage-gated channel subunit alpha1 S, [Score=1273, Expect=0.0]} {Mouse: ENSMUSG00000051331, Cacna1c, calcium channel, voltage-dependent, L type, alpha 1C subunit, [Score=1294, Expect=0.0]; ENSMUSG00000015968, Cacna1d, calcium channel, voltage-dependent, L type, alpha 1D subunit, [Score=1288, Expect=0.0]; ENSMUSG00000031142, Cacna1f, calcium channel, voltage-dependent, alpha 1F subunit, [Score=1276, Expect=0.0]; ENSMUSG00000026407, Cacna1s, calcium channel, voltage-dependent, L type, alpha 1S subunit, [Score=1260, Expect=0.0]} {Dmel: FBgn0001991, Ca-alpha1D, Ca[2+]-channel protein alpha[[1]] subunit D, [Score=1292, Expect=0.0]} {Celegans: WBGene00006742, unc-2, High voltage activated calcium channel alpha-1 subunit, [RH, Score=1690, Expect=0.0]} {Smed: dd_Smed_v6_13295_0_1, dd_Smed_v6_13295_0_1, [RH, Score=2129, Expect=0.0]} {RNA1509_11510} {RNA1310_2184.1} {RNA815_2606}
2. MligTC455_41326 407 8.48 Mlig455_011060

Neo: -

Age: -

KCNA2 3.693 - - 0.920 0.917 0.895 0.961 Mlig455_011060 {REF} {Length: 6096} {Pfam: Ion transport protein [PF00520.33, score=161.6]; BTB/POZ domain [PF02214.24, score=99.2]; Ion channel [PF07885.18, score=50.3]} {Human: ENSG00000177301, KCNA2, potassium voltage-gated channel subfamily A member 2, [RH, Score=620, Expect=0.0]; ENSG00000111262, KCNA1, potassium voltage-gated channel subfamily A member 1, [RH, Score=617, Expect=0.0]; ENSG00000177272, KCNA3, potassium voltage-gated channel subfamily A member 3, [RH, Score=611, Expect=0.0]} {Mouse: ENSMUSG00000040724, Kcna2, potassium voltage-gated channel, shaker-related subfamily, member 2, [RH, Score=619, Expect=0.0]; ENSMUSG00000047976, Kcna1, potassium voltage-gated channel, shaker-related subfamily, member 1, [RH, Score=617, Expect=0.0]; ENSMUSG00000047959, Kcna3, potassium voltage-gated channel, shaker-related subfamily, member 3, [RH, Score=607, Expect=0.0]} {Dmel: FBgn0003380, Sh, Shaker, [RH, Score=643, Expect=0.0]} {Celegans: WBGene00014261, shk-1, Potassium voltage-gated channel protein shk-1, [RH, Score=383, Expect=6e-127]} {Smed: dd_Smed_v6_15425_0_1, dd_Smed_v6_15425_0_1, [RH, Score=715, Expect=0.0]} {RNA1509_19798} {RNA1310_8877, RNA1509_19798} {RNA1509_19798, RNA815_8082.1}
3. MligTC455_35063 359 7.49 Mlig455_017090

Neo: -

Age: logFC(26M/2M)=-0.336

Region-enriched R2: 2.861/0.00814

DNM1 3.674 - - 0.917 0.986 0.983 0.788 Mlig455_017090 {REF} {Length: 4208} {Pfam: Dynamin central region [PF01031.22, score=334.5]; Dynamin family [PF00350.25, score=184.2]; Dynamin GTPase effector domain [PF02212.20, score=80.3]; PH domain [PF00169.31, score=37.3]; 50S ribosome-binding GTPase [PF01926.25, score=21.3]} {Human: ENSG00000106976, DNM1, dynamin 1, [RH, Score=1101, Expect=0.0]; ENSG00000197959, DNM3, dynamin 3, [RH, Score=1094, Expect=0.0]; ENSG00000079805, DNM2, dynamin 2, [RH, Score=1075, Expect=0.0]} {Mouse: ENSMUSG00000026825, Dnm1, dynamin 1, [RH, Score=1102, Expect=0.0]; ENSMUSG00000040265, Dnm3, dynamin 3, [RH, Score=1089, Expect=0.0]; ENSMUSG00000033335, Dnm2, dynamin 2, [RH, Score=1074, Expect=0.0]} {Dmel: FBgn0003392, shi, shibire, [RH, Score=1074, Expect=0.0]} {Celegans: WBGene00001130, dyn-1, Dynamin, [RH, Score=984, Expect=0.0]} {Smed: dd_Smed_v6_6863_0_1, dd_Smed_v6_6863_0_1, [RH, Score=1068, Expect=0.0]} {RNA1509_31451, RNA1509_50695} {RNA1310_8903.1, RNA1509_31451, RNA1509_50695} {RNA1509_31451, RNA1509_50695, RNA815_1703.1}
4. MligTC455_23031 559 11.65 Mlig455_004920, Mlig455_019740

Neo: -

Age: logFC(26M/2M)=0.748

NLK 3.653 - - 0.957 0.954 0.934 0.808

Mlig455_004920 {REF} {Length: 2917} {Pfam: Protein kinase domain [PF00069.27, score=199.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=99.1]; Phosphotransferase enzyme family [PF01636.25, score=23.6]; Fungal protein kinase [PF17667.3, score=21.1]; ABC1 atypical kinase-like domain [PF03109.18, score=18.6]} {Human: ENSG00000087095, NLK, nemo like kinase, [Score=380, Expect=2e-126]} {Mouse: ENSMUSG00000017376, Nlk, nemo like kinase, [Score=380, Expect=1e-126]} {Dmel: FBgn0011817, nmo, nemo, [Score=369, Expect=7e-124]} {Celegans: WBGene00003048, lit-1, Serine/threonine kinase NLK, [Score=347, Expect=4e-115]} {Smed: dd_Smed_v6_4172_0_3, dd_Smed_v6_4172_0_3, [Score=350, Expect=3e-116]} {RNA1310_28916} {RNA815_34936}

Mlig455_019740 {REF} {Length: 3316} {Pfam: Protein kinase domain [PF00069.27, score=199.5]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=99.1]; Phosphotransferase enzyme family [PF01636.25, score=22.2]; Fungal protein kinase [PF17667.3, score=21.2]; ABC1 atypical kinase-like domain [PF03109.18, score=18.6]} {Human: ENSG00000087095, NLK, nemo like kinase, [Score=367, Expect=9e-122]} {Mouse: ENSMUSG00000017376, Nlk, nemo like kinase, [Score=367, Expect=7e-122]} {Dmel: FBgn0011817, nmo, nemo, [Score=364, Expect=2e-122]} {Celegans: WBGene00003048, lit-1, Serine/threonine kinase NLK, [Score=344, Expect=3e-114]} {Smed: dd_Smed_v6_4172_0_3, dd_Smed_v6_4172_0_3, [Score=351, Expect=8e-117]} {RNA1310_28916} {RNA815_34936}
5. MligTC455_26766 638 13.3 Mlig455_017977

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.360

Region-enriched R2: 3.395/0.00052

3.258 0.765 - - 0.814 0.950 0.729 Mlig455_017977 {REF} {Length: 2516} {Smed: dd_Smed_v6_10627_0_1, dd_Smed_v6_10627_0_1, [Score=249, Expect=3e-71]} {RNA1509_19813} {RNA1310_621} {RNA815_183.1}
6. MligTC455_26765 686 14.29 Mlig455_006971

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.201/0.00046

3.236 0.751 - - 0.808 0.951 0.726 Mlig455_006971 {REF} {Length: 6360} {Pfam: Cadherin domain [PF00028.19, score=29.2]} {Smed: dd_Smed_v6_10627_0_1, dd_Smed_v6_10627_0_1, [RH, Score=328, Expect=1e-93]} {RNA1509_19813, RNA1509_5311} {RNA1310_621, RNA1509_19813, RNA1509_5311} {RNA1509_19813, RNA1509_5311, RNA815_183.1}
7. MligTC455_46584 107 2.22 Mlig455_010128

Neo: -

Age: Up-Down-Down

KCNC2 2.782 - - 0.980 - 0.969 0.833 Mlig455_010128 {REF} {Length: 1706} {Human: ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=74.3, Expect=3e-15]} {Mouse: ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=74.3, Expect=3e-16]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=114, Expect=3e-29]} {Celegans: WBGene00001202, egl-36, Potassium voltage-gated channel protein egl-36, [Score=100, Expect=1e-24]} {Smed: dd_Smed_v6_17998_0_1, dd_Smed_v6_17998_0_1, [Score=118, Expect=1e-32]} {RNA1310_24374} {RNA815_11270}
8. MligTC455_33343 459 9.56 Mlig455_063303

Neo: -

Age: -

Region-enriched R2: 1.600/0.01675

ITPR1 2.78 - - 0.949 - 0.879 0.952 Mlig455_063303 {REF} {Length: 3962} {Pfam: RyR and IP3R Homology associated [PF08454.13, score=68.3]; Ion transport protein [PF00520.33, score=28.7]} {Human: ENSG00000150995, ITPR1, inositol 1,4,5-trisphosphate receptor type 1, [Score=166, Expect=6e-41]} {Mouse: ENSMUSG00000030102, Itpr1, inositol 1,4,5-trisphosphate receptor 1, [Score=182, Expect=7e-46]} {Dmel: FBgn0010051, Itp-r83A, Inositol 1,4,5,-tris-phosphate receptor, [Score=179, Expect=4e-45]} {Celegans: WBGene00002173, itr-1, Inositol 1,4,5-trisphosphate receptor itr-1, [Score=155, Expect=5e-38]} {Smed: dd_Smed_v6_3814_1_1, dd_Smed_v6_3814_1_1, [Score=1044, Expect=0.0]} {RNA1509_30811} {RNA1310_939} {RNA815_220}
9. MligTC455_32624 513 10.69 Mlig455_049590

Neo: -

Age: -

Region-enriched R2: 2.722/0.00305

2.767 - - - 0.962 0.959 0.846 Mlig455_049590 {REF} {Length: 2947} {Smed: dd_Smed_v6_7527_0_1, dd_Smed_v6_7527_0_1, [RH, Score=84.0, Expect=5e-17]} {RNA1509_22587} {RNA1310_6575.1, RNA1509_22587} {RNA1509_22587, RNA815_5684.1}
10. MligTC455_41077 483 10.07 Mlig455_031143, Mlig455_031151

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.359

SLC8A3 2.757 - - 0.970 - 0.906 0.881

Mlig455_031143 {REF} {Length: 4359} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=180.5]; Calx-beta domain [PF03160.16, score=179.5]; C-terminal extension of sodium/calcium exchanger domain [PF16494.7, score=92.3]} {Human: ENSG00000100678, SLC8A3, solute carrier family 8 member A3, [RH, Score=952, Expect=0.0]; ENSG00000183023, SLC8A1, solute carrier family 8 member A1, [RH, Score=932, Expect=0.0]} {Mouse: ENSMUSG00000079055, Slc8a3, solute carrier family 8 (sodium/calcium exchanger), member 3, [RH, Score=945, Expect=0.0]; ENSMUSG00000054640, Slc8a1, solute carrier family 8 (sodium/calcium exchanger), member 1, [RH, Score=936, Expect=0.0]; ENSMUSG00000030376, Slc8a2, solute carrier family 8 (sodium/calcium exchanger), member 2, [RH, Score=917, Expect=0.0]} {Dmel: FBgn0013995, Calx, Na/Ca-exchange protein, [RH, Score=829, Expect=0.0]} {Celegans: WBGene00003567, ncx-2, Na/Ca eXchangers, [RH, Score=878, Expect=0.0]} {Smed: dd_Smed_v6_3303_0_1, dd_Smed_v6_3303_0_1, [RH, Score=997, Expect=0.0]} {RNA1509_12866} {RNA1310_2685.1} {RNA815_13452}

Mlig455_031151 {REF} {Length: 5266} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=179.9]; Calx-beta domain [PF03160.16, score=164.6]; C-terminal extension of sodium/calcium exchanger domain [PF16494.7, score=91.7]} {Human: ENSG00000100678, SLC8A3, solute carrier family 8 member A3, [Score=523, Expect=1e-169]; ENSG00000183023, SLC8A1, solute carrier family 8 member A1, [Score=498, Expect=7e-160]} {Mouse: ENSMUSG00000079055, Slc8a3, solute carrier family 8 (sodium/calcium exchanger), member 3, [Score=520, Expect=3e-168]; ENSMUSG00000054640, Slc8a1, solute carrier family 8 (sodium/calcium exchanger), member 1, [Score=503, Expect=7e-162]} {Dmel: FBgn0013995, Calx, Na/Ca-exchange protein, [Score=490, Expect=2e-160]} {Celegans: WBGene00003567, ncx-2, Na/Ca eXchangers, [Score=492, Expect=5e-158]} {Smed: dd_Smed_v6_3303_0_1, dd_Smed_v6_3303_0_1, [Score=549, Expect=4e-180]} {RNA1509_12866} {RNA1310_2685.2} {RNA815_13452}
11. MligTC455_11473 248 5.17 Mlig455_009711, Mlig455_071036

Neo: -

Age: Down-Up-Down

CHRNA3 2.75 0.815 - - 0.975 0.960 -

Mlig455_009711 {REF} {Length: 2402} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=241.4]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=222.9]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=391, Expect=2e-130]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=379, Expect=6e-126]; ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=375, Expect=2e-124]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=390, Expect=2e-130]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=375, Expect=2e-124]} {Dmel: FBgn0000038, nAChRbeta1, nicotinic Acetylcholine Receptor beta1, [RH, Score=499, Expect=9e-173]} {Celegans: WBGene00000043, acr-3, Acetylcholine receptor subunit beta-type acr-3, [RH, Score=426, Expect=6e-145]} {Smed: dd_Smed_v6_12146_0_1, dd_Smed_v6_12146_0_1, [Score=510, Expect=1e-176]} {RNA1509_48201} {RNA1310_10118} {RNA815_29940}

Mlig455_071036 {REF} {Length: 746} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=28.1]} {Dmel: FBgn0000038, nAChRbeta1, nicotinic Acetylcholine Receptor beta1, [Score=63.5, Expect=2e-13]} {Celegans: WBGene00000042, acr-2, Acetylcholine receptor subunit beta-type acr-2, [Score=63.9, Expect=9e-14]} {Smed: dd_Smed_v6_12535_0_1, dd_Smed_v6_12535_0_1, [Score=64.3, Expect=6e-14]} {RNA1310_21182} {RNA815_29940}
12. MligTC455_39736 474 9.86 Mlig455_014716

Neo: -

Age: Up-Down-Up

2.723 - - 0.923 0.966 0.834 - Mlig455_014716 {REF} {Length: 3097} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4537) [PF15057.8, score=61.8]; von Willebrand factor type A domain [PF13768.8, score=19.6]} {Smed: dd_Smed_v6_10837_0_1, dd_Smed_v6_10837_0_1, [RH, Score=97.4, Expect=1e-20]} {RNA1509_28750} {RNA1310_4730} {RNA815_8808}
13. MligTC455_31805 747 15.56 Mlig455_070318

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.499

EFCAB6 2.706 - - 0.950 0.938 0.818 - Mlig455_070318 {REF} {Length: 3714} {Pfam: EF-hand domain pair [PF13499.8, score=82.4]; EF-hand domain [PF08976.13, score=72.0]; EF-hand domain pair [PF13833.8, score=64.0]; EF-hand domain [PF13405.8, score=56.9]; EF hand [PF00036.34, score=53.2]; EF-hand domain [PF14658.8, score=34.9]; Family of unknown function (DUF5580) [PF17743.3, score=27.9]; EF hand [PF13202.8, score=22.4]} {Human: ENSG00000186976, EFCAB6, EF-hand calcium binding domain 6, [Score=86.3, Expect=2e-16]} {Mouse: ENSMUSG00000022441, Efcab6, EF-hand calcium binding domain 6, [Score=76.6, Expect=1e-13]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=48.9, Expect=2e-06]} {Celegans: WBGene00017394, cal-8, CALmodulin related genes, [Score=50.8, Expect=4e-07]} {Smed: dd_Smed_v6_20435_0_1, dd_Smed_v6_20435_0_1, [Score=157, Expect=1e-40]} {RNA1509_7148} {RNA1310_3069.1} {RNA815_3758}
14. MligTC455_33842 492 10.26 Mlig455_004899

Neo: -

Age: -

Region-enriched R2: 2.178/0.01972

CDKL1 2.694 - - - 0.921 0.984 0.789 Mlig455_004899 {REF} {Length: 2500} {Pfam: Protein kinase domain [PF00069.27, score=247.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=116.6]; Haspin like kinase domain [PF12330.10, score=18.7]; ABC1 atypical kinase-like domain [PF03109.18, score=18.6]} {Human: ENSG00000100490, CDKL1, cyclin dependent kinase like 1, [RH, Score=429, Expect=3e-150]; ENSG00000205111, CDKL4, cyclin dependent kinase like 4, [RH, Score=422, Expect=2e-148]} {Mouse: ENSMUSG00000020990, Cdkl1, cyclin-dependent kinase-like 1 (CDC2-related kinase), [RH, Score=432, Expect=7e-152]; ENSMUSG00000033966, Cdkl4, cyclin-dependent kinase-like 4, [RH, Score=423, Expect=3e-148]} {Dmel: FBgn0031730, CG7236, [RH, Score=381, Expect=6e-131]} {Celegans: WBGene00012779, cdkl-1, Cyclin-Dependent Kinase-Like, [RH, Score=396, Expect=4e-136]} {Smed: dd_Smed_v6_9353_0_1, dd_Smed_v6_9353_0_1, [RH, Score=481, Expect=5e-171]} {RNA1509_19679} {RNA1310_6686.1} {RNA815_5397}
15. MligTC455_33199 144 3 Mlig455_068562

Neo: -

Age: -

CAMKK2 2.653 - 0.781 0.961 - 0.911 - Mlig455_068562 {REF} {Length: 3078} {Pfam: Protein kinase domain [PF00069.27, score=209.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=121.7]; Kinase-like [PF14531.8, score=30.4]; Fungal protein kinase [PF17667.3, score=19.0]} {Human: ENSG00000110931, CAMKK2, calcium/calmodulin dependent protein kinase kinase 2, [RH, Score=417, Expect=4e-138]} {Mouse: ENSMUSG00000029471, Camkk2, calcium/calmodulin-dependent protein kinase kinase 2, beta, [RH, Score=409, Expect=4e-135]; ENSMUSG00000020785, Camkk1, calcium/calmodulin-dependent protein kinase kinase 1, alpha, [RH, Score=394, Expect=1e-129]} {Dmel: FBgn0040056, CG17698, [RH, Score=402, Expect=1e-130]} {Celegans: WBGene00000518, ckk-1, Calcium/calmodulin-dependent protein kinase kinase, [RH, Score=414, Expect=3e-137]} {Smed: dd_Smed_v6_18437_0_1, dd_Smed_v6_18437_0_1, [RH, Score=367, Expect=3e-118]} {RNA1509_51718} {RNA1310_7593.1} {RNA815_7566}
16. MligTC455_18122 1083 22.57 Mlig455_020157

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.614

Region-specific R2: 4.994

Region-enriched R2: 4.087/0.00011

2.619 0.767 - - 0.955 0.897 - Mlig455_020157 {REF} {Length: 2290} {RNA1310_56029} {RNA815_34539}
17. MligTC455_46341 243 5.06 Mlig455_052880, Mlig455_052884

Neo: -

Age: -

2.606 - - 0.963 - 0.936 0.707

Mlig455_052880 {REF} {Length: 1228} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=28.6]; Dpy-30 motif [PF05186.15, score=22.0]; Ankyrin repeats (many copies) [PF13637.8, score=20.9]} {Smed: dd_Smed_v6_29956_0_1, dd_Smed_v6_29956_0_1, [Score=60.5, Expect=6e-10]} {RNA1509_39973} {RNA1310_21889} {RNA815_13094}

Mlig455_052884 {REF} {Length: 1926} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=39.4]; Ankyrin repeats (many copies) [PF13637.8, score=27.7]; Ankyrin repeats (many copies) [PF13857.8, score=24.6]; Dpy-30 motif [PF05186.15, score=21.6]} {Smed: dd_Smed_v6_29956_0_1, dd_Smed_v6_29956_0_1, [Score=72.8, Expect=1e-13]} {RNA1509_39973} {RNA1310_21889, RNA1509_39973} {RNA1509_39973, RNA815_13094}
18. MligTC455_46120 185 3.86 Mlig455_042356

Neo: -

Age: -

2.583 - - 0.955 - 0.866 0.762 Mlig455_042356 {REF} {Length: 1296} {RNA1509_23490} {RNA1310_21881} {RNA815_8961}
19. MligTC455_38205 600 12.5 Mlig455_057698

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.274

2.579 - - 0.784 - 0.810 0.985 Mlig455_057698 {REF} {Length: 1671} {Pfam: Protein of unknown function with motif GDWWSH [PF15667.7, score=76.0]} {Smed: dd_Smed_v6_6622_0_1, dd_Smed_v6_6622_0_1, [RH, Score=116, Expect=1e-30]} {RNA1509_16386} {RNA1310_17948.1} {RNA815_6839.1}
20. MligTC455_42484 246 5.12 Mlig455_046416

Neo: -

Age: Down-Up-Down

Region-specific R2: 4.313

Region-enriched R2: 2.983/0.00930

2.542 - - 0.731 - 0.965 0.846 Mlig455_046416 {REF} {Length: 1006} {RNA1310_40237.1} {RNA815_18246}
21. MligTC455_42598 125 2.61 Mlig455_046563

Neo: -

Age: Up-Down-Down

EML1 2.54 - - 0.956 - 0.749 0.835 Mlig455_046563 {REF} {Length: 4903} {Pfam: HELP motif [PF03451.16, score=64.1]; WD domain, G-beta repeat [PF00400.34, score=32.8]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=29.2]; Transcription factor IIA, alpha/beta subunit [PF03153.15, score=25.5]} {Human: ENSG00000066629, EML1, echinoderm microtubule associated protein like 1, [Score=261, Expect=1e-72]; ENSG00000125746, EML2, echinoderm microtubule associated protein like 2, [Score=260, Expect=2e-72]} {Mouse: ENSMUSG00000058070, Eml1, echinoderm microtubule associated protein like 1, [Score=268, Expect=4e-75]; ENSMUSG00000040811, Eml2, echinoderm microtubule associated protein like 2, [Score=267, Expect=1e-74]} {Dmel: FBgn0259099, DCX-EMAP, Doublecortin-domain-containing echinoderm-microtubule-associated protein, [Score=214, Expect=3e-56]} {Celegans: WBGene00001248, elp-1, Echinoderm microtubule-associated protein-like elp-1, [Score=140, Expect=1e-33]} {Smed: dd_Smed_v6_14226_0_1, dd_Smed_v6_14226_0_1, [Score=323, Expect=4e-92]} {RNA1310_20242} {RNA815_18784}
22. MligTC455_49005 642 13.37 Mlig455_043634

Neo: -

Age: -

CCDC180 2.535 - - 0.813 0.956 0.766 - Mlig455_043634 {REF} {Length: 3450} {Pfam: Domain of unknown function (DUF4456) [PF14644.8, score=137.1]} {Human: ENSG00000197816, CCDC180, coiled-coil domain containing 180, [Score=160, Expect=2e-41]} {Mouse: ENSMUSG00000035539, Ccdc180, coiled-coil domain containing 180, [Score=110, Expect=3e-25]} {Smed: dd_Smed_v6_12302_0_1, dd_Smed_v6_12302_0_1, [Score=166, Expect=4e-44]} {RNA1509_8832} {RNA1310_898.2} {RNA815_8511}
23. MligTC455_35174 342 7.13 Mlig455_009545, Mlig455_054086

Neo: -

Age: Up-Down-Down

PTPRN2 2.525 - - 0.986 - 0.816 0.723

Mlig455_009545 {REF} {Length: 87} {NoTransDecoderORF} {RNA1509_3577} {RNA1310_173.2} {RNA815_26664}

Mlig455_054086 {REF} {Length: 10208} {Pfam: Protein-tyrosine phosphatase [PF00102.29, score=222.7]} {Human: ENSG00000155093, PTPRN2, protein tyrosine phosphatase, receptor type N2, [RH, Score=412, Expect=1e-129]} {Mouse: ENSMUSG00000056553, Ptprn2, protein tyrosine phosphatase, receptor type, N polypeptide 2, [RH, Score=407, Expect=7e-128]} {Dmel: FBgn0031294, IA-2, IA-2 protein tyrosine phosphatase, [RH, Score=376, Expect=8e-114]} {Celegans: WBGene00002048, ida-1, IA2; IDA-1 protein; Related to Islet cell Diabetes Autoantigen, [Score=280, Expect=1e-82]} {Smed: dd_Smed_v6_6990_0_1, dd_Smed_v6_6990_0_1, [RH, Score=391, Expect=8e-125]} {RNA1509_34721, RNA1509_41198} {RNA1310_3634, RNA1509_34721, RNA1509_41198} {RNA1509_34721, RNA1509_41198, RNA815_1727.1}
24. MligTC455_16847 1240 25.83 Mlig455_051898, Mlig455_053146

Neo: -

Age: Down-Up-Down

Region-specific R2: 5.478

Region-enriched R2: 5.690/0.00000

PRSS33 2.502 - - - 0.786 0.954 0.762

Mlig455_051898 {REF} {Length: 1360} {Pfam: Trypsin [PF00089.28, score=189.8]; Domain of unknown function (DUF1986) [PF09342.13, score=27.3]; Trypsin-like peptidase domain [PF13365.8, score=26.9]} {Human: ENSG00000103355, PRSS33, serine protease 33, [Score=159, Expect=4e-46]} {Mouse: ENSMUSG00000016942, Tmprss6, transmembrane serine protease 6, [Score=153, Expect=9e-41]; ENSMUSG00000037129, Tmprss13, transmembrane protease, serine 13, [Score=150, Expect=2e-40]; ENSMUSG00000059406, Tmprss9, transmembrane protease, serine 9, [Score=148, Expect=6e-39]; ENSMUSG00000022857, Tmprss15, transmembrane protease, serine 15, [Score=147, Expect=2e-38]} {Dmel: FBgn0036287, CG10663, [Score=146, Expect=1e-38]} {Celegans: WBGene00006620, svh-1, HGF/MSP/plasminogen-like protein, [Score=124, Expect=6e-31]} {Smed: dd_Smed_v6_10267_0_1, dd_Smed_v6_10267_0_1, [Score=178, Expect=4e-53]} {RNA1509_29335} {RNA1310_23561} {RNA815_9840}

Mlig455_053146 {REF} {Length: 1448} {Pfam: Trypsin [PF00089.28, score=189.8]; Domain of unknown function (DUF1986) [PF09342.13, score=27.3]; Trypsin-like peptidase domain [PF13365.8, score=26.9]} {Human: ENSG00000103355, PRSS33, serine protease 33, [Score=159, Expect=4e-46]} {Mouse: ENSMUSG00000016942, Tmprss6, transmembrane serine protease 6, [Score=153, Expect=9e-41]; ENSMUSG00000037129, Tmprss13, transmembrane protease, serine 13, [Score=150, Expect=2e-40]; ENSMUSG00000059406, Tmprss9, transmembrane protease, serine 9, [Score=148, Expect=6e-39]; ENSMUSG00000022857, Tmprss15, transmembrane protease, serine 15, [Score=147, Expect=2e-38]} {Dmel: FBgn0036287, CG10663, [Score=146, Expect=1e-38]} {Celegans: WBGene00006620, svh-1, HGF/MSP/plasminogen-like protein, [Score=124, Expect=6e-31]} {Smed: dd_Smed_v6_10267_0_1, dd_Smed_v6_10267_0_1, [Score=178, Expect=4e-53]} {RNA1509_26566, RNA1509_29335} {RNA1310_23561, RNA1509_26566, RNA1509_29335} {RNA1509_26566, RNA1509_29335, RNA815_9840}
25. MligTC455_25042 739 15.39 Mlig455_020224

Neo: -

Age: -

CAPSL 2.491 - - 0.951 - 0.705 0.835 Mlig455_020224 {REF} {Length: 1450} {TRANSSPLICED} {Pfam: EF-hand domain [PF13405.8, score=71.1]; EF-hand domain pair [PF13499.8, score=66.4]; EF hand [PF00036.34, score=64.5]; EF-hand domain pair [PF13833.8, score=46.7]; EF hand [PF13202.8, score=44.2]; p25-alpha [PF05517.14, score=21.2]} {Human: ENSG00000152611, CAPSL, calcyphosine like, [RH, Score=260, Expect=8e-88]} {Mouse: ENSMUSG00000039676, Capsl, calcyphosine-like, [RH, Score=267, Expect=1e-90]} {Dmel: FBgn0051345, CG31345, [RH, Score=246, Expect=2e-82]} {Celegans: WBGene00000288, cal-4, CALmodulin related genes, [Score=61.6, Expect=2e-11]} {Smed: dd_Smed_v6_7209_0_1, dd_Smed_v6_7209_0_1, [RH, Score=283, Expect=3e-97]} {RNA1509_22937} {RNA1310_18304.1} {RNA815_12484.1}
26. MligTC455_46793 652 13.58 Mlig455_058553

Neo: -

Age: -

SYTL4 2.487 - - 0.798 - 0.984 0.705 Mlig455_058553 {REF} {Length: 2601} {TRANSSPLICED} {Pfam: C2 domain [PF00168.32, score=103.1]} {Human: ENSG00000102362, SYTL4, synaptotagmin like 4, [Score=153, Expect=2e-38]; ENSG00000147041, SYTL5, synaptotagmin like 5, [Score=150, Expect=2e-37]; ENSG00000142765, SYTL1, synaptotagmin like 1, [Score=149, Expect=1e-37]} {Mouse: ENSMUSG00000031255, Sytl4, synaptotagmin-like 4, [Score=160, Expect=6e-41]} {Dmel: FBgn0266756, btsz, bitesize, [Score=193, Expect=2e-51]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=86.3, Expect=1e-17]} {Smed: dd_Smed_v6_10375_0_1, dd_Smed_v6_10375_0_1, [RH, Score=157, Expect=3e-40]} {RNA1509_50455} {RNA1310_5507.1, RNA1509_50455} {RNA1509_50455, RNA815_17811}
27. MligTC455_25135 288 6 Mlig455_001749, Mlig455_001771

Neo: -

Age: -

Region-enriched R2: 2.329/0.04280

P2RX4 2.485 0.720 - 0.959 - 0.806 -

Mlig455_001749 {REF} {Length: 2951} {Pfam: ATP P2X receptor [PF00864.21, score=341.3]} {Human: ENSG00000135124, P2RX4, purinergic receptor P2X 4, [Score=247, Expect=3e-75]; ENSG00000187848, P2RX2, purinergic receptor P2X 2, [Score=235, Expect=5e-70]} {Mouse: ENSMUSG00000029470, P2rx4, purinergic receptor P2X, ligand-gated ion channel 4, [Score=248, Expect=1e-75]; ENSMUSG00000029503, P2rx2, purinergic receptor P2X, ligand-gated ion channel, 2, [Score=236, Expect=3e-70]} {Smed: dd_Smed_v6_10968_0_1, dd_Smed_v6_10968_0_1, [Score=316, Expect=7e-101]} {RNA1509_56054} {RNA1310_19416, RNA1509_56054} {RNA1509_56054, RNA815_42167}

Mlig455_001771 {REF} {Length: 2484} {Pfam: ATP P2X receptor [PF00864.21, score=341.3]} {Human: ENSG00000135124, P2RX4, purinergic receptor P2X 4, [Score=247, Expect=3e-75]; ENSG00000187848, P2RX2, purinergic receptor P2X 2, [Score=235, Expect=5e-70]} {Mouse: ENSMUSG00000029470, P2rx4, purinergic receptor P2X, ligand-gated ion channel 4, [Score=248, Expect=1e-75]; ENSMUSG00000029503, P2rx2, purinergic receptor P2X, ligand-gated ion channel, 2, [Score=236, Expect=3e-70]} {Smed: dd_Smed_v6_10968_0_1, dd_Smed_v6_10968_0_1, [Score=316, Expect=7e-101]} {RNA1509_56054} {RNA1310_19416} {RNA815_42167}
28. MligTC455_35411 583 12.15 Mlig455_064235

Neo: -

Age: -

PPP3CA 2.469 0.756 - - - 0.958 0.755 Mlig455_064235 {REF} {Length: 3595} {Human: ENSG00000138814, PPP3CA, protein phosphatase 3 catalytic subunit alpha, [Score=156, Expect=8e-46]; ENSG00000107758, PPP3CB, protein phosphatase 3 catalytic subunit beta, [Score=149, Expect=4e-43]} {Mouse: ENSMUSG00000028161, Ppp3ca, protein phosphatase 3, catalytic subunit, alpha isoform, [Score=158, Expect=1e-46]} {Dmel: FBgn0011826, Pp2B-14D, Protein phosphatase 2B at 14D, [Score=159, Expect=1e-46]} {Celegans: WBGene00006527, tax-6, Serine/threonine-protein phosphatase 2B catalytic subunit, [Score=115, Expect=1e-30]} {Smed: dd_Smed_v6_5669_1_2, dd_Smed_v6_5669_1_2, [Score=155, Expect=7e-49]} {RNA1509_42566} {RNA1310_30586} {RNA815_21103.2}
29. MligTC455_34738 836 17.41 Mlig455_032157, Mlig455_032163, Mlig455_067631

Neo: -

Age: -

2.446 - - 0.975 - 0.764 0.707

Mlig455_032157 {REF} {Length: 1841} {Pfam: Stathmin family [PF00836.21, score=49.5]} {Smed: dd_Smed_v6_512_0_1, dd_Smed_v6_512_0_1, [RH, Score=80.5, Expect=2e-21]} {RNA1509_18048, RNA1509_6791} {RNA1310_32272, RNA1509_18048, RNA1509_6791} {RNA1509_18048, RNA1509_6791, RNA815_831}

Mlig455_032163 {REF} {Length: 1001} {Pfam: Stathmin family [PF00836.21, score=44.6]} {Smed: dd_Smed_v6_512_0_1, dd_Smed_v6_512_0_1, [RH, Score=84.0, Expect=3e-22]} {RNA1509_6791} {RNA1310_71333} {RNA815_831}

Mlig455_067631 {REF} {Length: 817} {Pfam: Stathmin family [PF00836.21, score=31.3]} {RNA1509_6791} {RNA1310_71333} {RNA815_831}
30. MligTC455_39663 257 5.36 Mlig455_035826

Neo: -

Age: -

Region-enriched R2: 2.079/0.03628

ERG 2.443 0.707 - 0.984 - - 0.752 Mlig455_035826 {REF} {Length: 1844} {Pfam: Ets-domain [PF00178.24, score=118.3]} {Human: ENSG00000157554, ERG, ERG, ETS transcription factor, [RH, Score=206, Expect=1e-62]; ENSG00000151702, FLI1, Fli-1 proto-oncogene, ETS transcription factor, [RH, Score=200, Expect=1e-62]} {Mouse: ENSMUSG00000040732, Erg, ETS transcription factor, [RH, Score=204, Expect=2e-62]; ENSMUSG00000016087, Fli1, Friend leukemia integration 1, [RH, Score=200, Expect=2e-60]} {Dmel: FBgn0005658, Ets65A, Ets at 65A, [RH, Score=211, Expect=3e-67]} {Celegans: WBGene00020368, ast-1, Axon STeering defect, [RH, Score=185, Expect=5e-56]} {Smed: dd_Smed_v6_11113_0_1, dd_Smed_v6_11113_0_1, [RH, Score=237, Expect=2e-76]} {RNA1509_29423} {RNA1310_27275.1, RNA1509_29423} {RNA1509_29423, RNA815_13091}
31. MligTC455_44999 2214 46.12 Mlig455_067394, Mlig455_069538

Neo: -

Age: Down-Up-Up

Region-enriched R2: 2.840/0.00027

2.441 0.717 - - - 0.955 0.769

Mlig455_067394 {REF} {Length: 401} {RNA1509_52966} {RNA1310_68651, RNA1509_52966} {RNA1509_52966, RNA815_33112.1}

Mlig455_069538 {REF} {Length: 1759} {Celegans: WBGene00001446, flp-3, FMRFamide-like neuropeptides 3 SPLGTMRF-amide TPLGTMRF-amide SAEPFGTMRF-amide NPENDTPFGTMRF-amide ASEDALFGTMRF-amide EAEEPLGTMRF-amide SADDSAPFGTMRF-amide NPLGTMRF-amide, [Score=45.8, Expect=1e-06]} {RNA1509_13671} {RNA1310_56061} {RNA815_33112.1}
32. MligTC455_44328 858 17.88 Mlig455_026172

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.714

Region-enriched R2: 4.385/0.00000

2.392 0.719 - - - 0.958 0.715 Mlig455_026172 {REF} {Length: 661} {RNA1509_32102, RNA1509_34635} {RNA1310_60068, RNA1509_32102, RNA1509_34635} {RNA1509_32102, RNA1509_34635, RNA815_37486}
33. MligTC455_40125 953 19.86 Mlig455_005600, Mlig455_014458

Neo: -

Age: Up-Down-Down

KIF13B, KIF1B 1.955 - - - 0.982 0.973 -

Mlig455_005600 {REF} {Length: 4684} {Pfam: Kinesin protein 1B [PF12423.10, score=42.5]} {Human: ENSG00000197892, KIF13B, kinesin family member 13B, [Score=61.6, Expect=2e-09]} {Mouse: ENSMUSG00000087236, Kif28, kinesin family member 28, [Score=98.2, Expect=4e-21]} {Dmel: FBgn0019968, Khc-73, Kinesin heavy chain 73, [Score=57.0, Expect=3e-08]} {Celegans: WBGene00002218, klp-6, Kinesin-like protein, [Score=177, Expect=5e-48]} {Smed: dd_Smed_v6_20223_0_1, dd_Smed_v6_20223_0_1, [Score=118, Expect=3e-28]} {RNA1509_6760} {RNA1310_2628} {RNA815_4402}

Mlig455_014458 {REF} {Length: 3819} {Pfam: Kinesin motor domain [PF00225.25, score=336.4]; Microtubule binding [PF16796.7, score=68.9]; Kinesin protein 1B [PF12423.10, score=40.0]; Kinesin-associated [PF16183.7, score=27.3]} {Human: ENSG00000054523, KIF1B, kinesin family member 1B, [Score=404, Expect=2e-123]; ENSG00000137177, KIF13A, kinesin family member 13A, [Score=404, Expect=9e-120]; ENSG00000130294, KIF1A, kinesin family member 1A, [Score=404, Expect=2e-120]; ENSG00000197892, KIF13B, kinesin family member 13B, [Score=399, Expect=2e-125]; ENSG00000129250, KIF1C, kinesin family member 1C, [Score=398, Expect=2e-121]} {Mouse: ENSMUSG00000087236, Kif28, kinesin family member 28, [Score=568, Expect=0.0]} {Dmel: FBgn0019968, Khc-73, Kinesin heavy chain 73, [Score=415, Expect=5e-124]} {Celegans: WBGene00002218, klp-6, Kinesin-like protein, [RH, Score=818, Expect=0.0]} {Smed: dd_Smed_v6_12573_0_1, dd_Smed_v6_12573_0_1, [Score=617, Expect=0.0]} {RNA1509_6760} {RNA1310_1667.1} {RNA815_1144}
34. MligTC455_40878 355 7.39 Mlig455_014130

Neo: -

Age: -

1.941 - - 0.970 - 0.971 - Mlig455_014130 {REF} {Length: 1465} {RNA1509_7458} {RNA1310_36212} {RNA815_1610.1}
35. MligTC455_47601 126 2.62 Mlig455_056477

Neo: -

Age: Up-Down-Up

NRXN1 1.936 - - - 0.974 0.962 - Mlig455_056477 {REF} {Length: 3481} {Pfam: Laminin G domain [PF02210.26, score=58.3]; Laminin G domain [PF00054.25, score=43.2]; Syndecan domain [PF01034.22, score=27.4]} {Human: ENSG00000179915, NRXN1, neurexin 1, [Score=142, Expect=4e-35]} {Mouse: ENSMUSG00000024109, Nrxn1, neurexin I, [Score=142, Expect=1e-35]} {Dmel: FBgn0038975, Nrx-1, Neurexin 1, [Score=102, Expect=2e-22]} {Smed: dd_Smed_v6_13697_0_1, dd_Smed_v6_13697_0_1, [Score=142, Expect=8e-36]} {RNA1509_55888} {RNA1310_37025, RNA1509_55888} {RNA1509_55888, RNA815_22404}
36. MligTC455_47808 151 3.15 Mlig455_066806

Neo: -

Age: -

STAC2 1.918 - - 0.962 - 0.956 - Mlig455_066806 {REF} {Length: 4661} {Pfam: SH3 domain [PF00018.30, score=41.7]; Variant SH3 domain [PF14604.8, score=35.5]} {Human: ENSG00000141750, STAC2, SH3 and cysteine rich domain 2, [RH, Score=72.8, Expect=1e-12]} {Mouse: ENSMUSG00000017400, Stac2, SH3 and cysteine rich domain 2, [RH, Score=72.0, Expect=2e-12]} {Dmel: FBgn0263980, CG43729, [RH, Score=149, Expect=5e-36]} {Celegans: WBGene00006791, unc-57, Endophilin-A homolog, [Score=53.9, Expect=2e-08]} {Smed: dd_Smed_v6_14652_0_1, dd_Smed_v6_14652_0_1, [Score=172, Expect=1e-43]} {RNA1509_54523} {RNA1310_1618} {RNA815_6997}
37. MligTC455_43962 120 2.5 Mlig455_020783

Neo: -

Age: -

TRAF5 1.908 - - 0.953 - 0.955 - Mlig455_020783 {REF} {Length: 3242} {Human: ENSG00000082512, TRAF5, TNF receptor associated factor 5, [Score=90.5, Expect=3e-20]} {Mouse: ENSMUSG00000026637, Traf5, TNF receptor-associated factor 5, [Score=88.6, Expect=1e-20]; ENSMUSG00000111385, Traf5, TNF receptor-associated factor 5, [Score=88.6, Expect=1e-20]} {Dmel: FBgn0026319, Traf4, TNF-receptor-associated factor 4, [Score=70.9, Expect=6e-14]} {Celegans: WBGene00006612, trf-1, TNF Receptor Associated Factor (TRAF) homolog; TRF-1, [Score=99.0, Expect=8e-24]} {Smed: dd_Smed_v6_13517_0_1, dd_Smed_v6_13517_0_1, [Score=132, Expect=8e-36]} {RNA1310_36792.1} {RNA815_40908}
38. MligTC455_47704 106 2.21 Mlig455_032247

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.432

WSCD2 1.907 - - 0.972 - 0.935 - Mlig455_032247 {REF} {Length: 2305} {Pfam: WSC domain [PF01822.21, score=58.4]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=54.7, Expect=1e-07]; ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=52.8, Expect=5e-07]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=56.6, Expect=3e-08]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=63.9, Expect=1e-10]} {RNA1509_59284} {RNA1310_13567} {RNA815_27780}
39. MligTC455_05720 156 3.26 Mlig455_040120

Neo: -

Age: -

CHRNB3 1.903 - - 0.980 - 0.923 - Mlig455_040120 {REF} {Length: 1839} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=153.5]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=90.2]} {Human: ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=205, Expect=1e-59]; ENSG00000169684, CHRNA5, cholinergic receptor nicotinic alpha 5 subunit, [Score=204, Expect=4e-59]; ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=197, Expect=3e-56]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=197, Expect=3e-56]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=196, Expect=7e-56]} {Mouse: ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=206, Expect=5e-60]; ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=201, Expect=5e-58]; ENSMUSG00000035594, Chrna5, cholinergic receptor, nicotinic, alpha polypeptide 5, [Score=197, Expect=4e-57]} {Dmel: FBgn0032151, nAChRalpha6, nicotinic Acetylcholine Receptor alpha6, [Score=204, Expect=3e-59]} {Celegans: WBGene00000055, acr-16, Acetylcholine receptor subunit alpha-type acr-16, [Score=201, Expect=5e-58]} {Smed: dd_Smed_v6_10322_0_1, dd_Smed_v6_10322_0_1, [Score=364, Expect=8e-120]} {RNA1310_53963} {RNA815_48325}
40. MligTC455_42963 247 5.15 Mlig455_002825

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.597

Region-enriched R2: 5.687/0.00012

1.903 - - - 0.948 0.955 - Mlig455_002825 {REF} {Length: 726} {RNA1310_78982} {RNA815_41084}
41. MligTC455_17197 170 3.54 Mlig455_053652

Neo: -

Age: -

1.9 - - - 0.939 0.961 - Mlig455_053652 {REF} {Length: 2429} {TRANSSPLICED} {RNA1509_44480} {RNA1310_34935, RNA1509_44480} {RNA1509_44480, RNA815_20343}
42. MligTC455_52722 1007 20.97 Mlig455_019980, Mlig455_038108

Neo: -

Age: -

CELF3 1.899 - - 0.923 - 0.976 -

Mlig455_019980 {REF} {Length: 4713} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=125.3]} {Human: ENSG00000159409, CELF3, CUGBP Elav-like family member 3, [Score=317, Expect=6e-103]; ENSG00000161082, CELF5, CUGBP Elav-like family member 5, [Score=315, Expect=8e-102]} {Mouse: ENSMUSG00000028137, Celf3, CUGBP, Elav-like family member 3, [Score=319, Expect=2e-103]; ENSMUSG00000024268, Celf4, CUGBP, Elav-like family member 4, [Score=312, Expect=1e-100]} {Dmel: FBgn0000114, bru1, bruno 1, [Score=243, Expect=2e-73]} {Celegans: WBGene00006807, unc-75, Putative RNA-binding protein, [RH, Score=172, Expect=3e-48]} {Smed: dd_Smed_v6_11349_0_1, dd_Smed_v6_11349_0_1, [RH, Score=366, Expect=1e-122]} {RNA1509_17477} {RNA1310_8180} {RNA815_3761.1}

Mlig455_038108 {REF} {Length: 3254} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=125.3]} {Human: ENSG00000159409, CELF3, CUGBP Elav-like family member 3, [Score=317, Expect=6e-103]; ENSG00000161082, CELF5, CUGBP Elav-like family member 5, [Score=315, Expect=8e-102]} {Mouse: ENSMUSG00000028137, Celf3, CUGBP, Elav-like family member 3, [Score=319, Expect=2e-103]; ENSMUSG00000024268, Celf4, CUGBP, Elav-like family member 4, [Score=312, Expect=1e-100]} {Dmel: FBgn0000114, bru1, bruno 1, [Score=243, Expect=2e-73]} {Celegans: WBGene00006807, unc-75, Putative RNA-binding protein, [RH, Score=172, Expect=3e-48]} {Smed: dd_Smed_v6_11349_0_1, dd_Smed_v6_11349_0_1, [RH, Score=366, Expect=1e-122]} {RNA1509_17477} {RNA1310_2810} {RNA815_3761.1}
43. MligTC455_44050 2086 43.46 Mlig455_028045, Mlig455_028051

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.242

Region-specific R2: 6.161

Region-enriched R2: 7.072/0.00000
Region-enriched R3: 3.149/0.00025

1.898 - - - 0.986 0.912 -

Mlig455_028045 {REF} {Length: 1156} {RNA1509_31459, RNA1509_3903} {RNA1310_2730.2, RNA1509_31459, RNA1509_3903} {RNA1509_31459, RNA1509_3903, RNA815_7682}

Mlig455_028051 {REF} {Length: 871} {NoTransDecoderORF} {RNA1509_3903} {RNA1310_15260} {RNA815_7682}
44. MligTC455_42088 72 1.5 Mlig455_028244

Neo: -

Age: -

1.898 - - 0.942 - 0.956 - Mlig455_028244 {REF} {Length: 2632} {RNA1509_40406} {RNA1310_12938} {RNA815_16887}
45. MligTC455_37343 240 4.99 Mlig455_024086

Neo: -

Age: Up-Down-Up

Region-enriched R8: 2.659/0.04266

1.894 - - 0.953 - 0.941 - Mlig455_024086 {REF} {Length: 4209} {RNA1509_36528, RNA1509_59718} {RNA1310_12514, RNA1509_36528, RNA1509_59718} {RNA1509_36528, RNA1509_59718, RNA815_21020}
46. MligTC455_45914 359 7.49 Mlig455_025337

Neo: -

Age: logFC(26M/2M)=-0.269

TRAF3IP1 1.886 - - 0.934 - - 0.952 Mlig455_025337 {REF} {Length: 2762} {TRANSSPLICED} {Pfam: Microtubule-binding protein MIP-T3 C-terminal region [PF17749.3, score=131.6]; Microtubule-binding protein MIP-T3 CH-like domain [PF10243.11, score=42.6]; Takusan [PF04822.15, score=19.2]} {Human: ENSG00000204104, TRAF3IP1, TRAF3 interacting protein 1, [Score=198, Expect=2e-55]} {Mouse: ENSMUSG00000034292, Traf3ip1, TRAF3 interacting protein 1, [RH, Score=189, Expect=2e-52]} {Dmel: FBgn0086707, ncm, nucampholin, [Score=48.9, Expect=1e-05]} {Celegans: WBGene00001127, dyf-11, [Score=67.4, Expect=1e-11]} {Smed: dd_Smed_v6_10562_0_1, dd_Smed_v6_10562_0_1, [Score=168, Expect=1e-45]} {RNA1509_5107} {RNA1310_14186.2} {RNA815_2859}
47. MligTC455_17393 345 7.18 Mlig455_019018, Mlig455_055685

Neo: -

Age: -

ANKDD1A 1.884 - - 0.906 - 0.978 -

Mlig455_019018 {REF} {Length: 2636} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=191.1]; Ankyrin repeats (many copies) [PF13637.8, score=165.7]; Ankyrin repeat [PF13606.8, score=151.2]; Ankyrin repeats (many copies) [PF13857.8, score=149.5]; Ankyrin repeat [PF00023.32, score=143.3]; Death domain [PF00531.24, score=29.5]} {Human: ENSG00000166839, ANKDD1A, ankyrin repeat and death domain containing 1A, [RH, Score=266, Expect=9e-82]} {Mouse: ENSMUSG00000066510, Ankdd1a, ankyrin repeat and death domain containing 1A, [RH, Score=273, Expect=2e-84]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=139, Expect=6e-34]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=131, Expect=1e-31]} {Smed: dd_Smed_v6_7532_0_1, dd_Smed_v6_7532_0_1, [RH, Score=464, Expect=2e-158]} {RNA1509_56207} {RNA1310_4362} {RNA815_20274}

Mlig455_055685 {REF} {Length: 2672} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=191.4]; Ankyrin repeats (many copies) [PF13637.8, score=165.4]; Ankyrin repeat [PF13606.8, score=149.6]; Ankyrin repeats (many copies) [PF13857.8, score=148.6]; Ankyrin repeat [PF00023.32, score=142.4]; Death domain [PF00531.24, score=29.5]} {Human: ENSG00000166839, ANKDD1A, ankyrin repeat and death domain containing 1A, [RH, Score=267, Expect=7e-82]} {Mouse: ENSMUSG00000066510, Ankdd1a, ankyrin repeat and death domain containing 1A, [RH, Score=273, Expect=2e-84]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=137, Expect=1e-33]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=131, Expect=1e-31]} {Smed: dd_Smed_v6_7532_0_1, dd_Smed_v6_7532_0_1, [RH, Score=466, Expect=7e-159]} {RNA1509_56207} {RNA1310_4362, RNA1509_56207} {RNA1509_56207, RNA815_20274}
48. MligTC455_49825 543 11.31 Mlig455_069114

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.806

Region-enriched R2: 3.936/0.00000

1.884 - - 0.925 - 0.959 - Mlig455_069114 {REF} {Length: 828} {Celegans: WBGene00003748, nlp-10, Neuropeptide-Like Protein, [Score=40.0, Expect=9e-06]} {RNA1509_26665} {RNA1310_48731, RNA1509_26665} {RNA1509_26665, RNA815_24488}
49. MligTC455_04162 131 2.73 Mlig455_028924

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.575

HMCN1 1.879 - - 0.960 - 0.919 - Mlig455_028924 {REF} {Length: 3929} {Pfam: Immunoglobulin domain [PF13927.8, score=144.9]; Immunoglobulin I-set domain [PF07679.18, score=119.8]; Immunoglobulin domain [PF13895.8, score=113.4]; Immunoglobulin domain [PF00047.27, score=102.3]; Immunoglobulin V-set domain [PF07686.19, score=36.7]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=35.3]; Immunoglobulin C1-set domain [PF07654.17, score=23.3]; C17orf99 Ig domain [PF17736.3, score=20.9]; Immunoglobulin domain [PF18452.3, score=19.8]} {Human: ENSG00000143341, HMCN1, hemicentin 1, [Score=103, Expect=2e-21]; ENSG00000148357, HMCN2, hemicentin 2, [Score=100, Expect=8e-21]} {Mouse: ENSMUSG00000051747, Ttn, titin, [Score=107, Expect=5e-23]; ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=103, Expect=7e-22]} {Dmel: FBgn0000547, ed, echinoid, [Score=147, Expect=2e-35]} {Celegans: WBGene00001863, him-4, Hemicentin; High Incidence of Males (Increased X chromosome loss), [Score=100, Expect=3e-21]} {Smed: dd_Smed_v6_13903_0_1, dd_Smed_v6_13903_0_1, [Score=162, Expect=2e-40]} {RNA1310_26618} {RNA815_41641}
50. MligTC455_36628 477 9.95 Mlig455_047554, Mlig455_047565

Neo: -

Age: -

Region-enriched R4: 2.246/0.02774

1.878 - - 0.957 - 0.921 -

Mlig455_047554 {REF} {Length: 2406} {Smed: dd_Smed_v6_2397_0_1, dd_Smed_v6_2397_0_1, [Score=367, Expect=6e-122]} {RNA1509_25988, RNA1509_46354} {RNA1310_10207, RNA1509_25988} {RNA1509_25988, RNA815_3595}

Mlig455_047565 {REF} {Length: 1169} {Smed: dd_Smed_v6_2397_0_1, dd_Smed_v6_2397_0_1, [Score=92.4, Expect=7e-23]} {RNA1509_46354} {RNA1310_10207} {RNA815_3595}
51. MligTC455_23142 769 16.02 Mlig455_008044

Neo: -

Age: -

INSR 1.876 - - - 0.977 0.899 - Mlig455_008044 {REF} {Length: 5353} {TRANSSPLICED} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=291.8]; Protein kinase domain [PF00069.27, score=128.4]; Receptor L domain [PF01030.26, score=118.4]; Furin-like cysteine rich region [PF00757.22, score=79.0]; Fibronectin type III domain [PF00041.23, score=45.0]; Growth factor receptor domain IV [PF14843.8, score=19.9]} {Human: ENSG00000171105, INSR, insulin receptor, [RH, Score=647, Expect=0.0]} {Mouse: ENSMUSG00000005534, Insr, insulin receptor, [RH, Score=643, Expect=0.0]} {Dmel: FBgn0283499, InR, Insulin-like receptor, [RH, Score=333, Expect=8e-93]} {Celegans: WBGene00000898, daf-2, Insulin-like receptor Insulin-like receptor subunit alpha Insulin-like receptor subunit beta, [RH, Score=474, Expect=3e-140]} {Smed: dd_Smed_v6_9006_0_1, dd_Smed_v6_9006_0_1, [RH, Score=514, Expect=3e-157]} {RNA1509_5152} {RNA1310_762.1} {RNA815_285.1}
52. MligTC455_33552 905 18.86 Mlig455_014406, Mlig455_070160

Neo: -

Age: Up-Down-Down

Region-enriched R2: 2.705/0.03873

KCNH1 1.876 - - - 0.926 0.950 -

Mlig455_014406 {REF} {Length: 5774} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=54.1]} {Human: ENSG00000143473, KCNH1, potassium voltage-gated channel subfamily H member 1, [Score=269, Expect=1e-82]; ENSG00000283965, KCNH1, potassium voltage-gated channel subfamily H member 1, [Score=269, Expect=1e-82]; ENSG00000140015, KCNH5, potassium voltage-gated channel subfamily H member 5, [Score=256, Expect=1e-74]} {Mouse: ENSMUSG00000058248, Kcnh1, potassium voltage-gated channel, subfamily H (eag-related), member 1, [Score=267, Expect=4e-79]; ENSMUSG00000034402, Kcnh5, potassium voltage-gated channel, subfamily H (eag-related), member 5, [Score=256, Expect=3e-75]} {Dmel: FBgn0000535, eag, ether a go-go, [Score=283, Expect=5e-84]} {Celegans: WBGene00001171, egl-2, EAG K+ channel EGL-2, [Score=240, Expect=1e-69]} {Smed: dd_Smed_v6_23063_0_1, dd_Smed_v6_23063_0_1, [Score=283, Expect=7e-86]} {RNA1509_16580} {RNA1310_9615} {RNA815_20522}

Mlig455_070160 {REF} {Length: 3641} {Pfam: Ion transport protein [PF00520.33, score=111.5]; Cyclic nucleotide-binding domain [PF00027.31, score=53.3]; Ion channel [PF07885.18, score=40.6]} {Human: ENSG00000143473, KCNH1, potassium voltage-gated channel subfamily H member 1, [Score=795, Expect=0.0]; ENSG00000283965, KCNH1, potassium voltage-gated channel subfamily H member 1, [Score=795, Expect=0.0]; ENSG00000140015, KCNH5, potassium voltage-gated channel subfamily H member 5, [Score=771, Expect=0.0]} {Mouse: ENSMUSG00000058248, Kcnh1, potassium voltage-gated channel, subfamily H (eag-related), member 1, [Score=794, Expect=0.0]; ENSMUSG00000034402, Kcnh5, potassium voltage-gated channel, subfamily H (eag-related), member 5, [Score=770, Expect=0.0]} {Dmel: FBgn0000535, eag, ether a go-go, [Score=838, Expect=0.0]} {Celegans: WBGene00001171, egl-2, EAG K+ channel EGL-2, [Score=688, Expect=0.0]} {Smed: dd_Smed_v6_18793_0_1, dd_Smed_v6_18793_0_1, [Score=895, Expect=0.0]} {RNA1509_16580} {RNA1310_6070} {RNA815_18231}
53. MligTC455_20550 381 7.94 Mlig455_010388, Mlig455_028015

Neo: -

Age: -

Region-enriched R2: 1.910/0.04589

HMCN1, HMCN2 1.874 - - - 0.952 0.922 -

Mlig455_010388 {REF} {Length: 3305} {Pfam: Immunoglobulin domain [PF13927.8, score=93.2]; Immunoglobulin domain [PF13895.8, score=68.2]; Immunoglobulin I-set domain [PF07679.18, score=67.4]; Immunoglobulin domain [PF00047.27, score=64.7]; Fibronectin type III domain [PF00041.23, score=29.9]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=28.5]; Immunoglobulin V-set domain [PF07686.19, score=22.4]} {Human: ENSG00000143341, HMCN1, hemicentin 1, [Score=88.2, Expect=5e-17]; ENSG00000148357, HMCN2, hemicentin 2, [Score=85.5, Expect=3e-16]} {Mouse: ENSMUSG00000055632, Hmcn2, hemicentin 2, [Score=108, Expect=3e-23]} {Dmel: FBgn0000547, ed, echinoid, [Score=163, Expect=1e-40]} {Celegans: WBGene00001863, him-4, Hemicentin; High Incidence of Males (Increased X chromosome loss), [Score=77.8, Expect=3e-14]} {Smed: dd_Smed_v6_13903_0_1, dd_Smed_v6_13903_0_1, [Score=134, Expect=4e-32]} {RNA1310_22531.1} {RNA815_15161}

Mlig455_028015 {REF} {Length: 4677} {Pfam: Immunoglobulin domain [PF13927.8, score=161.8]; Immunoglobulin I-set domain [PF07679.18, score=106.9]; Immunoglobulin domain [PF00047.27, score=106.0]; Immunoglobulin domain [PF13895.8, score=103.4]; Immunoglobulin V-set domain [PF07686.19, score=56.4]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=48.7]; Fibronectin type III domain [PF00041.23, score=30.7]} {Human: ENSG00000148357, HMCN2, hemicentin 2, [Score=113, Expect=2e-24]} {Mouse: ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=135, Expect=2e-31]} {Dmel: FBgn0000547, ed, echinoid, [Score=216, Expect=7e-57]} {Celegans: WBGene00018215, igcm-1, ImmunoGlobulin-like Cell adhesion Molecule family, [Score=135, Expect=7e-32]} {Smed: dd_Smed_v6_13903_0_1, dd_Smed_v6_13903_0_1, [Score=186, Expect=7e-48]} {RNA1310_22531.1} {RNA815_15161}
54. MligTC455_16254 485 10.1 Mlig455_039657

Neo: -

Age: Up-Down-Down

1.869 - - 0.895 0.974 - - Mlig455_039657 {REF} {Length: 1117} {NoTransDecoderORF} {RNA1509_47868} {RNA1310_57969} {RNA815_28105}
55. MligTC455_53014 445 9.26 Mlig455_067846

Neo: -

Age: Down-Up-Down

1.866 - - 0.908 0.958 - - Mlig455_067846 {REF} {Length: 1248} {TRANSSPLICED} {RNA1509_24093} {RNA1310_63179} {RNA815_13022.1}
56. MligTC455_36362 266 5.55 Mlig455_029693, Mlig455_034838

Neo: -

Age: -

TLCD1 1.863 - - 0.899 - 0.964 -

Mlig455_029693 {REF} {Length: 2356} {Pfam: TLC domain [PF03798.18, score=71.5]} {Human: ENSG00000160606, TLCD1, TLC domain containing 1, [RH, Score=93.2, Expect=6e-22]} {Mouse: ENSMUSG00000019437, Tlcd1, TLC domain containing 1, [RH, Score=94.4, Expect=1e-22]} {Celegans: WBGene00013407, Y63D3A.8, [RH, Score=100, Expect=2e-24]} {Smed: dd_Smed_v6_6951_0_2, dd_Smed_v6_6951_0_2, [Score=237, Expect=1e-77]} {RNA1509_18403} {RNA1310_26765} {RNA815_14967}

Mlig455_034838 {REF} {Length: 4633} {Pfam: TLC domain [PF03798.18, score=71.6]} {Human: ENSG00000160606, TLCD1, TLC domain containing 1, [RH, Score=92.4, Expect=1e-21]} {Mouse: ENSMUSG00000019437, Tlcd1, TLC domain containing 1, [RH, Score=93.6, Expect=3e-22]} {Celegans: WBGene00013407, Y63D3A.8, [RH, Score=101, Expect=7e-25]} {Smed: dd_Smed_v6_6951_0_2, dd_Smed_v6_6951_0_2, [Score=236, Expect=4e-77]} {RNA1509_18403} {RNA1310_7362.1} {RNA815_6705.1}
57. MligTC455_46795 785 16.35 Mlig455_000535

Neo: -

Age: logFC(26M/2M)=-0.364

Region-enriched R2: 1.672/0.01916

HTR1B 1.862 - - - 0.965 0.897 - Mlig455_000535 {REF} {Length: 4573} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=255.2]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=53.3]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=23.4]; Family of unknown function (DUF5684) [PF18936.2, score=19.6]} {Human: ENSG00000135312, HTR1B, 5-hydroxytryptamine receptor 1B, [RH, Score=243, Expect=3e-75]} {Mouse: ENSMUSG00000021721, Htr1a, 5-hydroxytryptamine (serotonin) receptor 1A, [Score=251, Expect=3e-78]} {Dmel: FBgn0004573, 5-HT7, 5-hydroxytryptamine (serotonin) receptor 7, [RH, Score=276, Expect=2e-86]} {Celegans: WBGene00004780, ser-7, SERotonin/octopamine receptor family, [RH, Score=221, Expect=1e-66]} {Smed: dd_Smed_v6_5341_0_1, dd_Smed_v6_5341_0_1, [RH, Score=412, Expect=2e-140]} {RNA1509_11749, RNA1509_13593, RNA1509_37815} {RNA1310_3896.1, RNA1509_11749, RNA1509_13593, RNA1509_37815} {RNA1509_11749, RNA1509_13593, RNA1509_37815, RNA815_3010}
58. MligTC455_49957 119 2.47 Mlig455_005610, Mlig455_014448

Neo: -

Age: -

1.862 - - 0.975 - 0.887 -

Mlig455_005610 {REF} {Length: 1455} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=66.2, Expect=4e-13]} {RNA1310_45206} {RNA815_28788}

Mlig455_014448 {REF} {Length: 1455} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=63.2, Expect=6e-12]} {RNA1310_45206} {RNA815_28788}
59. MligTC455_19845 602 12.53 Mlig455_016261

Neo: -

Age: -

Region-enriched R2: 2.356/0.00003

STOM 1.858 - - - 0.976 0.882 - Mlig455_016261 {REF} {Length: 3265} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=111.1]; SPFH domain-Band 7 family [PF13421.8, score=20.1]} {Human: ENSG00000148175, STOM, stomatin, [RH, Score=357, Expect=4e-124]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [RH, Score=353, Expect=7e-123]} {Dmel: FBgn0260657, CG42540, [Score=359, Expect=8e-124]} {Celegans: WBGene00003166, mec-2, Mechanosensory protein 2, [RH, Score=384, Expect=1e-133]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [RH, Score=426, Expect=7e-152]} {RNA1509_58645} {RNA1310_17679} {RNA815_7364.1}
60. MligTC455_09317 1638 34.12 Mlig455_061529

Neo: -

Age: Down-Down-Up

1.85 - - 0.882 0.968 - - Mlig455_061529 {REF} {Length: 2922} {RNA1509_44877} {RNA1310_25423.1, RNA1509_44877} {RNA1509_44877, RNA815_162}
61. MligTC455_03382 210 4.37 Mlig455_057035

Neo: -

Age: -

Region-enriched R2: 3.628/0.00113

PDE1C 1.845 - - - 0.952 0.893 - Mlig455_057035 {REF} {Length: 2458} {Pfam: 3'5'-cyclic nucleotide phosphodiesterase [PF00233.21, score=275.1]; 3'5'-cyclic nucleotide phosphodiesterase N-terminal [PF08499.14, score=94.2]} {Human: ENSG00000154678, PDE1C, phosphodiesterase 1C, [RH, Score=546, Expect=0.0]} {Mouse: ENSMUSG00000004347, Pde1c, phosphodiesterase 1C, [RH, Score=546, Expect=0.0]} {Dmel: FBgn0264815, Pde1c, Phosphodiesterase 1c, [RH, Score=538, Expect=0.0]} {Celegans: WBGene00011433, pde-1, Probable 3',5'-cyclic phosphodiesterase pde-1, [RH, Score=482, Expect=2e-164]} {Smed: dd_Smed_v6_11039_0_2, dd_Smed_v6_11039_0_2, [RH, Score=613, Expect=0.0]} {RNA1509_46084} {RNA1310_8143.1} {RNA815_6002}
62. MligTC455_49690 72 1.5 Mlig455_068367

Neo: -

Age: Down-Down-Up

1.843 - - 0.950 - 0.893 - Mlig455_068367 {REF} {Length: 1546} {Smed: dd_Smed_v6_8297_0_1, dd_Smed_v6_8297_0_1, [RH, Score=53.1, Expect=2e-09]} {RNA1509_38073} {RNA1310_34998} {RNA815_20391}
63. MligTC455_20237 371 7.72 Mlig455_042388

Neo: -

Age: -

1.84 - - 0.885 0.955 - - Mlig455_042388 {REF} {Length: 3463} {RNA1509_32804} {RNA1310_15777} {RNA815_23756}
64. MligTC455_32582 524 10.91 Mlig455_010043

Neo: -

Age: -

SH3GL1 1.839 - - - - 0.950 0.889 Mlig455_010043 {REF} {Length: 4371} {Pfam: BAR domain [PF03114.20, score=223.0]; SH3 domain [PF00018.30, score=50.0]; Variant SH3 domain [PF14604.8, score=49.3]; Bin/amphiphysin/Rvs domain for vesicular trafficking [PF10455.11, score=48.7]; Variant SH3 domain [PF07653.19, score=45.4]} {Human: ENSG00000141985, SH3GL1, SH3 domain containing GRB2 like 1, endophilin A2, [RH, Score=348, Expect=4e-118]; ENSG00000140600, SH3GL3, SH3 domain containing GRB2 like 3, endophilin A3, [RH, Score=339, Expect=8e-115]} {Mouse: ENSMUSG00000003200, Sh3gl1, SH3-domain GRB2-like 1, [RH, Score=344, Expect=2e-116]} {Dmel: FBgn0038659, EndoA, Endophilin A, [RH, Score=76.6, Expect=3e-15]} {Celegans: WBGene00006791, unc-57, Endophilin-A homolog, [RH, Score=328, Expect=3e-110]} {Smed: dd_Smed_v6_6372_0_1, dd_Smed_v6_6372_0_1, [RH, Score=391, Expect=2e-135]} {RNA1509_53264} {RNA1310_24751} {RNA815_11391.1}
65. MligTC455_33861 424 8.83 Mlig455_015736, Mlig455_049442

Neo: -

Age: Up-Down-Up

Region-specific R2: 4.103

Region-enriched R2: 3.209/0.00115

EML1 1.836 - - - - 0.977 0.859

Mlig455_015736 {REF} {Length: 5118} {Pfam: Doublecortin [PF03607.19, score=58.2]; HELP motif [PF03451.16, score=47.1]; WD domain, G-beta repeat [PF00400.34, score=41.2]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=26.5]} {Human: ENSG00000066629, EML1, echinoderm microtubule associated protein like 1, [Score=317, Expect=3e-91]; ENSG00000143924, EML4, echinoderm microtubule associated protein like 4, [Score=313, Expect=7e-89]; ENSG00000125746, EML2, echinoderm microtubule associated protein like 2, [Score=307, Expect=2e-88]} {Mouse: ENSMUSG00000058070, Eml1, echinoderm microtubule associated protein like 1, [Score=324, Expect=3e-94]; ENSMUSG00000032624, Eml4, echinoderm microtubule associated protein like 4, [Score=321, Expect=1e-91]} {Dmel: FBgn0259099, DCX-EMAP, Doublecortin-domain-containing echinoderm-microtubule-associated protein, [Score=330, Expect=3e-96]} {Celegans: WBGene00001248, elp-1, Echinoderm microtubule-associated protein-like elp-1, [Score=129, Expect=6e-30]} {Smed: dd_Smed_v6_2493_0_1, dd_Smed_v6_2493_0_1, [Score=298, Expect=1e-83]} {RNA1509_31406} {RNA1310_20171} {RNA815_13503}

Mlig455_049442 {REF} {Length: 4806} {Pfam: Doublecortin [PF03607.19, score=58.7]; HELP motif [PF03451.16, score=47.6]; WD domain, G-beta repeat [PF00400.34, score=32.6]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=27.5]} {Human: ENSG00000066629, EML1, echinoderm microtubule associated protein like 1, [Score=317, Expect=4e-92]; ENSG00000143924, EML4, echinoderm microtubule associated protein like 4, [Score=311, Expect=7e-89]; ENSG00000125746, EML2, echinoderm microtubule associated protein like 2, [Score=308, Expect=5e-89]} {Mouse: ENSMUSG00000058070, Eml1, echinoderm microtubule associated protein like 1, [Score=324, Expect=3e-95]; ENSMUSG00000032624, Eml4, echinoderm microtubule associated protein like 4, [Score=319, Expect=1e-91]} {Dmel: FBgn0259099, DCX-EMAP, Doublecortin-domain-containing echinoderm-microtubule-associated protein, [Score=331, Expect=3e-97]} {Celegans: WBGene00001248, elp-1, Echinoderm microtubule-associated protein-like elp-1, [Score=133, Expect=2e-31]} {Smed: dd_Smed_v6_2493_0_1, dd_Smed_v6_2493_0_1, [Score=296, Expect=2e-83]} {RNA1509_31406} {RNA1310_20171} {RNA815_13503}
66. MligTC455_41471 131 2.72 Mlig455_040252, Mlig455_054698

Neo: -

Age: -

Region-enriched R2: 3.576/0.00566

ANGPTL1 1.836 - - 0.968 - 0.868 -

Mlig455_040252 {REF} {Length: 2778} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=120.9]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=112, Expect=2e-27]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=107, Expect=2e-25]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=109, Expect=2e-26]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=107, Expect=1e-25]} {Dmel: FBgn0050280, CG30280, [Score=93.6, Expect=5e-22]} {Celegans: WBGene00020516, T15B7.1, [Score=61.6, Expect=1e-10]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=100, Expect=9e-24]} {RNA1509_57196} {RNA1310_23214} {RNA815_19964}

Mlig455_054698 {REF} {Length: 3143} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=127.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=108, Expect=4e-26]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=105, Expect=6e-25]; ENSG00000160339, FCN2, ficolin 2, [Score=103, Expect=3e-25]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=105, Expect=3e-25]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=105, Expect=4e-25]; ENSMUSG00000026835, Fcnb, ficolin B, [Score=103, Expect=5e-25]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=103, Expect=2e-24]; ENSMUSG00000042436, Mfap4, microfibrillar-associated protein 4, [Score=102, Expect=4e-25]; ENSMUSG00000015829, Tnr, tenascin R, [Score=102, Expect=7e-24]; ENSMUSG00000026938, Fcna, ficolin A, [Score=102, Expect=9e-25]} {Dmel: FBgn0050280, CG30280, [Score=97.8, Expect=1e-23]} {Celegans: WBGene00020516, T15B7.1, [Score=62.0, Expect=9e-11]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=100, Expect=2e-23]} {RNA1310_23214} {RNA815_19964}
67. MligTC455_49620 290 6.04 Mlig455_001138, Mlig455_001300

Neo: -

Age: -

Region-enriched R2: 5.198/0.00000

ELAVL3, ELAVL4 1.828 - - - - 0.965 0.863

Mlig455_001138 {REF} {Length: 3131} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=206.7]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF13893.8, score=37.5]; Occluded RNA-recognition motif [PF16842.7, score=27.0]} {Human: ENSG00000162374, ELAVL4, ELAV like RNA binding protein 4, [Score=268, Expect=6e-85]; ENSG00000196361, ELAVL3, ELAV like RNA binding protein 3, [Score=268, Expect=3e-85]; ENSG00000107105, ELAVL2, ELAV like RNA binding protein 2, [Score=268, Expect=2e-84]} {Mouse: ENSMUSG00000003410, Elavl3, ELAV like RNA binding protein 3, [RH, Score=270, Expect=2e-87]} {Dmel: FBgn0010263, Rbp9, RNA-binding protein 9, [Score=273, Expect=2e-86]} {Celegans: WBGene00001368, exc-7, [RH, Score=327, Expect=6e-107]} {Smed: dd_Smed_v6_13151_0_1, dd_Smed_v6_13151_0_1, [RH, Score=269, Expect=8e-84]} {RNA1509_28072} {RNA1310_22289} {RNA815_15133}

Mlig455_001300 {REF} {Length: 3150} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=203.6]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF13893.8, score=36.4]; Occluded RNA-recognition motif [PF16842.7, score=27.0]} {Human: ENSG00000196361, ELAVL3, ELAV like RNA binding protein 3, [Score=274, Expect=4e-87]; ENSG00000162374, ELAVL4, ELAV like RNA binding protein 4, [Score=271, Expect=6e-86]; ENSG00000107105, ELAVL2, ELAV like RNA binding protein 2, [Score=268, Expect=3e-85]; ENSG00000066044, ELAVL1, ELAV like RNA binding protein 1, [Score=262, Expect=3e-83]} {Mouse: ENSMUSG00000003410, Elavl3, ELAV like RNA binding protein 3, [RH, Score=271, Expect=7e-88]} {Dmel: FBgn0010263, Rbp9, RNA-binding protein 9, [Score=270, Expect=4e-85]} {Celegans: WBGene00001368, exc-7, [RH, Score=326, Expect=1e-106]} {Smed: dd_Smed_v6_11311_0_2, dd_Smed_v6_11311_0_2, [RH, Score=300, Expect=2e-97]} {RNA1509_28072} {RNA1310_22289} {RNA815_15133}
68. MligTC455_13094 121 2.52 Mlig455_005442, Mlig455_005513

Neo: -

Age: Up-Up-Down

1.826 - - 0.957 - 0.869 -

Mlig455_005442 {REF} {Length: 3816} {Smed: dd_Smed_v6_15433_0_1, dd_Smed_v6_15433_0_1, [Score=141, Expect=1e-34]} {RNA1509_41201} {RNA1310_51044} {RNA815_32534}

Mlig455_005513 {REF} {Length: 685} {NoTransDecoderORF} {RNA1310_56412} {RNA815_32534}
69. MligTC455_47181 555 11.55 Mlig455_012909, Mlig455_012919, Mlig455_039828

Neo: -

Age: -

Region-enriched R2: 2.610/0.04973

1.821 - - - - 0.981 0.840

Mlig455_012909 {REF} {Length: 1504} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=48.7]} {Smed: dd_Smed_v6_9777_0_1, dd_Smed_v6_9777_0_1, [Score=161, Expect=3e-48]} {RNA1310_33903} {RNA815_16003}

Mlig455_012919 {REF} {Length: 1506} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=48.0]} {Smed: dd_Smed_v6_9777_0_1, dd_Smed_v6_9777_0_1, [RH, Score=203, Expect=3e-63]} {RNA1310_33903} {RNA815_16003}

Mlig455_039828 {REF} {Length: 1505} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=48.0]} {Smed: dd_Smed_v6_9777_0_1, dd_Smed_v6_9777_0_1, [RH, Score=203, Expect=3e-63]} {RNA1310_33903} {RNA815_16003}
70. MligTC455_48063 63 1.31 Mlig455_046268

Neo: -

Age: -

Region-enriched R2: 5.256/0.00170

1.821 - - 0.975 - 0.846 - Mlig455_046268 {REF} {Length: 749} {RNA1310_88363} {RNA815_47885}
71. MligTC455_44713 661 13.77 Mlig455_048154

Neo: -

Age: logFC(26M/2M)=0.569

Region-specific R2: 3.883

Region-enriched R2: 3.422/0.00000

1.82 - - - - 0.967 0.853 Mlig455_048154 {REF} {Length: 1173} {RNA1509_34252} {RNA1310_54269.1} {RNA815_55074}
72. MligTC455_25592 486 10.12 Mlig455_039559, Mlig455_051364

Neo: -

Age: -

1.818 - - - - 0.976 0.842

Mlig455_039559 {REF} {Length: 1517} {RNA1509_53070} {RNA1310_32642} {RNA815_19892}

Mlig455_051364 {REF} {Length: 1517} {RNA1509_53070} {RNA1310_32642, RNA1509_53070} {RNA1509_53070, RNA815_19892}
73. MligTC455_46155 116 2.42 Mlig455_027239

Neo: -

Age: -

Region-enriched R2: 4.163/0.03818

GRK3 1.809 - - - - 0.962 0.847 Mlig455_027239 {REF} {Length: 2919} {Pfam: Protein kinase domain [PF00069.27, score=226.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=100.5]; Regulator of G protein signaling domain [PF00615.21, score=48.3]} {Human: ENSG00000100077, GRK3, G protein-coupled receptor kinase 3, [Score=845, Expect=0.0]; ENSG00000173020, GRK2, G protein-coupled receptor kinase 2, [Score=838, Expect=0.0]} {Mouse: ENSMUSG00000042249, Grk3, G protein-coupled receptor kinase 3, [Score=838, Expect=0.0]; ENSMUSG00000024858, Grk2, G protein-coupled receptor kinase 2, [Score=838, Expect=0.0]} {Dmel: FBgn0260798, Gprk1, G protein-coupled receptor kinase 1, [Score=842, Expect=0.0]} {Celegans: WBGene00001709, grk-2, G protein-coupled receptor kinase 2, [Score=819, Expect=0.0]} {Smed: dd_Smed_v6_6480_0_1, dd_Smed_v6_6480_0_1, [Score=949, Expect=0.0]} {RNA1509_7002} {RNA1310_16658} {RNA815_28070}
74. MligTC455_42227 1213 25.28 Mlig455_004225, Mlig455_031049

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.914/0.00168

LRGUK 1.808 - - - 0.956 0.852 -

Mlig455_004225 {REF} {Length: 3526} {Pfam: Guanylate kinase [PF00625.23, score=97.8]; Leucine rich repeat [PF13855.8, score=83.2]; Leucine Rich repeats (2 copies) [PF12799.9, score=81.7]; Leucine-rich repeat [PF14580.8, score=68.6]; Leucine Rich repeat [PF13516.8, score=23.6]} {Human: ENSG00000155530, LRGUK, leucine rich repeats and guanylate kinase domain containing, [RH, Score=416, Expect=7e-131]} {Mouse: ENSMUSG00000056215, Lrguk, leucine-rich repeats and guanylate kinase domain containing, [RH, Score=429, Expect=3e-139]} {Dmel: FBgn0036099, CG11811, [Score=107, Expect=8e-26]} {Celegans: WBGene00011637, sds-22, Protein phosphatase 1 regulatory subunit SDS22 homolog, [Score=87.0, Expect=2e-18]} {Smed: dd_Smed_v6_9362_0_1, dd_Smed_v6_9362_0_1, [RH, Score=405, Expect=5e-131]} {RNA1509_3553} {RNA1310_6024.1, RNA1509_3553} {RNA1509_3553, RNA815_2429}

Mlig455_031049 {REF} {Length: 3115} {Pfam: Leucine rich repeat [PF13855.8, score=92.1]; Leucine Rich repeats (2 copies) [PF12799.9, score=86.2]; Leucine-rich repeat [PF14580.8, score=60.1]; Leucine Rich repeat [PF13516.8, score=24.3]; Guanylate kinase [PF00625.23, score=23.6]; Leucine Rich Repeat [PF00560.35, score=21.3]} {Human: ENSG00000155530, LRGUK, leucine rich repeats and guanylate kinase domain containing, [Score=281, Expect=3e-85]} {Mouse: ENSMUSG00000056215, Lrguk, leucine-rich repeats and guanylate kinase domain containing, [Score=276, Expect=7e-84]} {Dmel: FBgn0028992, sds22, [Score=71.2, Expect=3e-13]} {Celegans: WBGene00011637, sds-22, Protein phosphatase 1 regulatory subunit SDS22 homolog, [Score=91.3, Expect=4e-20]} {Smed: dd_Smed_v6_9362_0_1, dd_Smed_v6_9362_0_1, [Score=259, Expect=2e-78]} {RNA1509_3553} {RNA1310_6024.2} {RNA815_2429}
75. MligTC455_10667 475 9.89 Mlig455_060955

Neo: -

Age: -

1.807 - - 0.956 - 0.851 - Mlig455_060955 {REF} {Length: 1952} {TRANSSPLICED} {Pfam: CIDE-N domain [PF02017.17, score=44.6]} {RNA1509_6031} {RNA1310_3667, RNA1509_6031} {RNA1509_6031, RNA815_5199}
76. MligTC455_45538 379 7.89 Mlig455_054128, Mlig455_060668

Neo: -

Age: logFC(26M/2M)=-0.316

NPR1, NPR2 1.802 - - 0.964 - 0.838 -

Mlig455_054128 {REF} {Length: 4761} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=226.8]; Receptor family ligand binding region [PF01094.30, score=163.2]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=132.0]; Protein kinase domain [PF00069.27, score=110.8]} {Human: ENSG00000169418, NPR1, natriuretic peptide receptor 1, [Score=635, Expect=0.0]; ENSG00000159899, NPR2, natriuretic peptide receptor 2, [Score=622, Expect=0.0]} {Mouse: ENSMUSG00000028469, Npr2, natriuretic peptide receptor 2, [RH, Score=625, Expect=0.0]} {Dmel: FBgn0034568, CG3216, [RH, Score=693, Expect=0.0]} {Celegans: WBGene00020131, gcy-28, Receptor-type guanylate cyclase gcy-28, [RH, Score=839, Expect=0.0]} {Smed: dd_Smed_v6_7644_0_1, dd_Smed_v6_7644_0_1, [RH, Score=964, Expect=0.0]} {RNA1509_8682} {RNA1310_3172} {RNA815_455}

Mlig455_060668 {REF} {Length: 776} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=33.6]; Protein kinase domain [PF00069.27, score=23.5]} {Human: ENSG00000159899, NPR2, natriuretic peptide receptor 2, [Score=105, Expect=6e-28]} {Mouse: ENSMUSG00000028469, Npr2, natriuretic peptide receptor 2, [Score=105, Expect=4e-28]} {Dmel: FBgn0051183, CG31183, [Score=90.1, Expect=1e-22]} {Celegans: WBGene00020131, gcy-28, Receptor-type guanylate cyclase gcy-28, [Score=84.3, Expect=9e-21]} {Smed: dd_Smed_v6_14331_0_1, dd_Smed_v6_14331_0_1, [Score=106, Expect=1e-28]} {RNA1509_8682} {RNA1310_9433} {RNA815_455}
77. MligTC455_39860 56 1.17 Mlig455_046932

Neo: -

Age: -

1.799 - - 0.974 - 0.825 - Mlig455_046932 {REF} {Length: 920} {RNA1310_30968} {RNA815_45889}
78. MligTC455_16226 110 2.29 Mlig455_019579

Neo: -

Age: logFC(26M/2M)=-0.946

1.795 - - - - 0.962 0.833 Mlig455_019579 {REF} {Length: 2153} {Smed: dd_Smed_v6_16150_0_1, dd_Smed_v6_16150_0_1, [RH, Score=95.9, Expect=6e-21]} {RNA1509_34395} {RNA1310_13154} {RNA815_10500}
79. MligTC455_50915 531 11.06 Mlig455_028745

Neo: -

Age: Up-Down-Down

Region-enriched R2: 2.109/0.02468

DNHD1 1.79 - - - - 0.964 0.826 Mlig455_028745 {REF} {Length: 14999} {TRANSSPLICED} {Pfam: Dynein heavy chain, N-terminal region 2 [PF08393.15, score=214.3]; Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=113.4]; P-loop containing dynein motor region D4 [PF12780.9, score=60.1]; Microtubule-binding stalk of dynein motor [PF12777.9, score=55.6]; P-loop containing dynein motor region [PF12775.9, score=49.4]; Dynein heavy chain C-terminal domain [PF18199.3, score=44.7]; Dynein heavy chain AAA lid domain [PF17852.3, score=40.5]; AAA domain [PF13401.8, score=23.5]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=22.3]; Dynein heavy chain AAA lid domain [PF18198.3, score=22.0]; Protein of unknown function (DUF815) [PF05673.15, score=21.1]; AAA domain [PF13604.8, score=18.7]} {Human: ENSG00000179532, DNHD1, dynein heavy chain domain 1, [Score=157, Expect=4e-37]} {Mouse: ENSMUSG00000030882, Dnhd1, dynein heavy chain domain 1, [Score=249, Expect=8e-65]} {Dmel: FBgn0013811, Dhc62B, Dynein heavy chain at 62B, [Score=114, Expect=2e-24]} {Celegans: WBGene00000485, che-3, Cytoplasmic dynein 2 heavy chain 1, [Score=84.0, Expect=4e-15]} {Smed: dd_Smed_v6_8984_0_1, dd_Smed_v6_8984_0_1, [RH, Score=443, Expect=5e-124]} {RNA1509_1896} {RNA1310_31, RNA1509_1896} {RNA1509_1896, RNA815_1203}
80. MligTC455_52199 1032 21.49 Mlig455_031255, Mlig455_031301

Neo: -

Age: Down-Down-Up

1.79 - - - - 0.978 0.812

Mlig455_031255 {REF} {Length: 1896} {Pfam: Innexin [PF00876.20, score=210.3]} {Celegans: WBGene00002127, inx-5, Innexin-5, [Score=134, Expect=1e-34]} {Smed: dd_Smed_v6_734_0_1, dd_Smed_v6_734_0_1, [Score=139, Expect=1e-36]} {RNA1509_2324} {RNA1310_13247} {RNA815_6165.1}

Mlig455_031301 {REF} {Length: 2187} {Pfam: Innexin [PF00876.20, score=210.3]} {Celegans: WBGene00002127, inx-5, Innexin-5, [Score=134, Expect=1e-34]} {Smed: dd_Smed_v6_734_0_1, dd_Smed_v6_734_0_1, [Score=139, Expect=2e-36]} {RNA1509_2324} {RNA1310_13247} {RNA815_6165.1}
81. MligTC455_53382 110 2.28 Mlig455_006777

Neo: -

Age: -

1.784 0.795 - - - 0.989 - Mlig455_006777 {REF} {Length: 2841} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=54.8]} {Dmel: FBgn0039747, AdoR, Adenosine receptor, [Score=48.9, Expect=1e-05]} {Smed: dd_Smed_v6_8885_0_1, dd_Smed_v6_8885_0_1, [Score=137, Expect=6e-36]} {RNA1509_47534} {RNA1310_15311} {RNA815_12841}
82. MligTC455_54203 182 3.79 Mlig455_061249

Neo: -

Age: -

MYH7 1.779 - - 0.951 - 0.828 - Mlig455_061249 {REF} {Length: 1536} {Pfam: Myosin tail [PF01576.21, score=90.6]} {Human: ENSG00000092054, MYH7, myosin heavy chain 7, [Score=200, Expect=8e-57]; ENSG00000197616, MYH6, myosin heavy chain 6, [Score=198, Expect=4e-56]; ENSG00000264424, MYH4, myosin heavy chain 4, [Score=191, Expect=2e-53]; ENSG00000125414, MYH2, myosin heavy chain 2, [Score=190, Expect=4e-53]} {Mouse: ENSMUSG00000053093, Myh7, myosin, heavy polypeptide 7, cardiac muscle, beta, [Score=201, Expect=4e-57]; ENSMUSG00000040752, Myh6, myosin, heavy polypeptide 6, cardiac muscle, alpha, [Score=194, Expect=8e-55]; ENSMUSG00000057003, Myh4, myosin, heavy polypeptide 4, skeletal muscle, [Score=192, Expect=3e-54]; ENSMUSG00000056328, Myh1, myosin, heavy polypeptide 1, skeletal muscle, adult, [Score=191, Expect=1e-53]} {Dmel: FBgn0264695, Mhc, Myosin heavy chain, [Score=282, Expect=2e-85]} {Celegans: WBGene00003515, myo-3, Myosin-3, [Score=241, Expect=2e-71]} {Smed: dd_Smed_v6_432_0_1, dd_Smed_v6_432_0_1, [Score=285, Expect=9e-87]} {RNA1509_55838} {RNA1310_1388} {RNA815_21073}
83. MligTC455_24953 749 15.61 Mlig455_060716

Neo: -

Age: -

Region-specific R2: 5.313

Region-enriched R2: 5.509/0.00000

CCDC169 1.778 - - - - 0.952 0.826 Mlig455_060716 {REF} {Length: 1302} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4600) [PF15372.8, score=97.2]} {Human: ENSG00000242715, CCDC169, coiled-coil domain containing 169, [RH, Score=82.8, Expect=6e-19]} {Mouse: ENSMUSG00000048655, Ccdc169, coiled-coil domain containing 169, [RH, Score=94.0, Expect=3e-23]} {Smed: dd_Smed_v6_12011_0_1, dd_Smed_v6_12011_0_1, [RH, Score=207, Expect=9e-68]} {RNA1509_8270} {RNA1310_23029} {RNA815_11545}
84. MligTC455_10666 1029 21.43 Mlig455_033815, Mlig455_036255

Neo: -

Age: Down-Up-Down

1.777 - - 0.958 - 0.819 -

Mlig455_033815 {REF} {Length: 2235} {Pfam: CIDE-N domain [PF02017.17, score=45.6]} {RNA1509_6031} {RNA1310_3667} {RNA815_5199}

Mlig455_036255 {REF} {Length: 1884} {Pfam: CIDE-N domain [PF02017.17, score=46.3]} {RNA1509_6031} {RNA1310_3667} {RNA815_5199}
85. MligTC455_17018 93 1.93 Mlig455_008015

Neo: -

Age: logFC(26M/2M)=1.300

1.774 - - - - 0.975 0.799 Mlig455_008015 {REF} {Length: 1919} {TRANSSPLICED} {Pfam: Sleepless protein [PF17064.7, score=37.0]} {Dmel: FBgn0260499, qvr, quiver, [Score=69.7, Expect=2e-15]} {Smed: dd_Smed_v6_16907_0_2, dd_Smed_v6_16907_0_2, [Score=74.7, Expect=1e-17]} {RNA1310_61248} {RNA815_27518}
86. MligTC455_50807 576 12.01 Mlig455_028496

Neo: -

Age: Down-Down-Up

Region-enriched R2: 2.245/0.00284

1.773 - - - 0.801 0.972 - Mlig455_028496 {REF} {Length: 937} {Pfam: Pancreatic hormone peptide [PF00159.20, score=40.1]} {RNA1509_25155} {RNA1310_44043, RNA1509_25155} {RNA1509_25155, RNA815_21709}
87. MligTC455_37708 135 2.81 Mlig455_008316

Neo: -

Age: Down-Up-Down

1.773 - - 0.951 - 0.822 - Mlig455_008316 {REF} {Length: 3405} {Pfam: NHL repeat [PF01436.23, score=45.8]} {Mouse: ENSMUSG00000079259, Trim71, tripartite motif-containing 71, [Score=52.4, Expect=2e-06]} {Dmel: FBgn0265356, tn, thin, [Score=58.2, Expect=2e-08]} {Celegans: WBGene00003597, nhl-1, RING finger protein nhl-1, [Score=48.5, Expect=1e-05]} {Smed: dd_Smed_v6_14782_0_1, dd_Smed_v6_14782_0_1, [Score=47.8, Expect=1e-05]} {RNA1509_45609} {RNA1310_24165, RNA1509_45609} {RNA1509_45609, RNA815_29204.1}
88. MligTC455_41130 1186 24.72 Mlig455_000166, Mlig455_000179, Mlig455_067712

Neo: -

Age: Down-Up-Down

Region-specific R2: 5.626

Region-enriched R2: 4.906/0.00009

Regeneration-downregulated R3: -5.200

Regeneration-depleted R3: -5.200

1.768 0.816 - - - 0.952 -

Mlig455_000166 {REF} {Length: 479} {RNA1509_36590} {RNA1310_65705}

Mlig455_000179 {REF} {Length: 479} {RNA1509_36590} {RNA1310_65705}

Mlig455_067712 {REF} {Length: 479} {RNA1509_36590} {RNA1310_65705}
89. MligTC455_41980 1108 23.09 Mlig455_048223

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.452

Regeneration-depleted BL: -2.044
Regeneration-depleted R6: -1.918

1.759 - - 0.950 - 0.809 - Mlig455_048223 {REF} {Length: 1924} {Pfam: Domain of unknown function (DUF1330) [PF07045.13, score=28.5]} {Smed: dd_Smed_v6_8243_0_1, dd_Smed_v6_8243_0_1, [Score=117, Expect=5e-31]} {RNA1509_5489} {RNA1310_15598} {RNA815_10198.1}
90. MligTC455_52084 58 1.21 Mlig455_037061

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.495

FAT3 1.759 - - - - 0.801 0.958 Mlig455_037061 {REF} {Length: 9396} {Pfam: Cadherin domain [PF00028.19, score=292.6]; Laminin G domain [PF02210.26, score=96.4]; Cadherin cytoplasmic region [PF01049.19, score=79.9]; Laminin G domain [PF00054.25, score=77.6]; Cadherin-like [PF16184.7, score=57.7]; Cadherin-like [PF08266.14, score=21.5]} {Human: ENSG00000165323, FAT3, FAT atypical cadherin 3, [Score=283, Expect=2e-75]; ENSG00000282908, FAT3, FAT atypical cadherin 3, [Score=283, Expect=2e-75]} {Mouse: ENSMUSG00000074505, Fat3, FAT atypical cadherin 3, [Score=276, Expect=2e-73]; ENSMUSG00000070047, Fat1, FAT atypical cadherin 1, [Score=270, Expect=1e-71]} {Dmel: FBgn0015609, CadN, Cadherin-N, [RH, Score=719, Expect=0.0]} {Celegans: WBGene00001980, hmr-1, Cadherin-related hmr-1, [RH, Score=481, Expect=3e-136]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=177, Expect=6e-44]} {RNA1509_5439} {RNA1310_149} {RNA815_168}
91. MligTC455_40818 639 13.3 Mlig455_052157, Mlig455_054166, Mlig455_060705

Neo: -

Age: -

Region-enriched R2: 3.411/0.00218
Region-enriched R7: 2.728/0.03044

Regeneration-downregulated BL: -7.120

Regeneration-depleted BL: -7.120

1.755 - - - 0.967 0.788 -

Mlig455_052157 {REF} {Length: 1229} {RNA1310_27543} {RNA815_14190}

Mlig455_054166 {REF} {Length: 1295} {RNA1310_27543} {RNA815_14190}

Mlig455_060705 {REF} {Length: 1292} {RNA1310_27543} {RNA815_14190}
92. MligTC455_45557 629 13.1 Mlig455_015721

Neo: -

Age: -

Region-enriched R2: 1.212/0.04087

DYNLT1 1.755 - - - 0.965 - 0.790 Mlig455_015721 {REF} {Length: 1742} {TRANSSPLICED} {Pfam: Tctex-1 family [PF03645.15, score=89.2]} {Human: ENSG00000146425, DYNLT1, dynein light chain Tctex-type 1, [RH, Score=165, Expect=5e-49]} {Mouse: ENSMUSG00000092074, Dynlt1a, dynein light chain Tctex-type 1A, [RH, Score=161, Expect=8e-48]; ENSMUSG00000095677, Dynlt1f, dynein light chain Tctex-type 1F, [RH, Score=161, Expect=8e-48]; ENSMUSG00000000579, Dynlt1c, dynein light chain Tctex-type 1C, [RH, Score=161, Expect=8e-48]; ENSMUSG00000096255, Dynlt1b, dynein light chain Tctex-type 1B, [RH, Score=161, Expect=8e-48]} {Dmel: FBgn0024432, Dlc90F, Dynein light chain 90F, [Score=138, Expect=3e-39]} {Smed: dd_Smed_v6_1166_0_1, dd_Smed_v6_1166_0_1, [RH, Score=171, Expect=5e-52]} {RNA1509_42217} {RNA1310_25091} {RNA815_10285.1}
93. MligTC455_38419 298 6.22 Mlig455_055922

Neo: -

Age: -

1.753 0.795 - - - 0.958 - Mlig455_055922 {REF} {Length: 1428} {RNA1509_21831} {RNA1310_22461, RNA1509_21831} {RNA1509_21831, RNA815_11600}
94. MligTC455_18333 273 5.7 Mlig455_010935

Neo: -

Age: Down-Up-Up

Region-enriched R2: 5.059/0.00307

1.75 - - 0.798 - 0.952 - Mlig455_010935 {REF} {Length: 510} {RNA1310_33328.2} {RNA815_15093.1}
95. MligTC455_19275 407 8.47 Mlig455_037548

Neo: -

Age: logFC(26M/2M)=0.488

Region-enriched R2: 3.247/0.04164

CHRNA10 1.75 - - 0.963 - 0.787 - Mlig455_037548 {REF} {Length: 959} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=87.9]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=96.7, Expect=1e-22]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=97.1, Expect=7e-23]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=95.1, Expect=5e-22]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=110, Expect=1e-27]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=119, Expect=8e-31]} {Smed: dd_Smed_v6_18184_0_1, dd_Smed_v6_18184_0_1, [Score=93.2, Expect=1e-21]} {RNA1509_23115} {RNA1310_34970} {RNA815_15305.1}
96. MligTC455_24868 641 13.36 Mlig455_036744

Neo: -

Age: -

1.75 - - 0.967 - 0.783 - Mlig455_036744 {REF} {Length: 2718} {TRANSSPLICED} {Celegans: WBGene00021017, cil-7, CILiary localization, [RH, Score=238, Expect=4e-71]} {RNA1509_11135} {RNA1310_7801.1} {RNA815_4350.1}
97. MligTC455_23714 762 15.88 Mlig455_040957

Neo: -

Age: -

Region-specific R4: 5.231

Region-enriched R4: 3.728/0.00000

Regeneration-downregulated R4: -3.318

Regeneration-depleted R4: -3.318

NMBR 1.747 - 0.785 - 0.962 - - Mlig455_040957 {REF} {Length: 6201} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=123.6]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=36.5]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=32.2]; Serpentine type 7TM GPCR chemoreceptor Srv [PF10323.11, score=23.4]} {Human: ENSG00000135577, NMBR, neuromedin B receptor, [RH, Score=149, Expect=2e-40]} {Mouse: ENSMUSG00000019865, Nmbr, neuromedin B receptor, [RH, Score=148, Expect=3e-40]} {Dmel: FBgn0050106, CCHa1-R, CCHamide-1 receptor, [RH, Score=152, Expect=3e-41]} {Celegans: WBGene00012084, npr-15, Neuropeptide receptor 15, [Score=84.0, Expect=9e-18]} {Smed: dd_Smed_v6_17567_0_1, dd_Smed_v6_17567_0_1, [RH, Score=147, Expect=2e-40]} {RNA1509_16040, RNA1509_54082} {RNA1310_21210.1, RNA1509_16040, RNA1509_54082} {RNA1509_16040, RNA1509_54082, RNA815_16289}
98. MligTC455_46605 388 8.08 Mlig455_032055

Neo: -

Age: -

Region-specific R2: 4.152

1.746 - - - - 0.955 0.791 Mlig455_032055 {REF} {Length: 1416} {RNA1310_44339} {RNA815_20624}
99. MligTC455_45309 692 14.41 Mlig455_060249

Neo: -

Age: logFC(26M/2M)=-0.339

ROGDI 1.745 - - - 0.950 0.795 - Mlig455_060249 {REF} {Length: 2596} {TRANSSPLICED} {Pfam: Rogdi leucine zipper containing protein [PF10259.11, score=79.4]} {Human: ENSG00000067836, ROGDI, rogdi homolog, [RH, Score=82.8, Expect=2e-18]} {Mouse: ENSMUSG00000022540, Rogdi, rogdi homolog, [RH, Score=83.6, Expect=1e-18]} {Dmel: FBgn0036697, rogdi, [RH, Score=104, Expect=4e-26]} {Celegans: WBGene00019196, H14A12.3, Protein rogdi homolog, [RH, Score=68.6, Expect=2e-13]} {Smed: dd_Smed_v6_4687_0_1, dd_Smed_v6_4687_0_1, [RH, Score=110, Expect=1e-29]} {RNA1509_30038, RNA1509_39875} {RNA1310_24614, RNA1509_30038, RNA1509_39875} {RNA1509_30038, RNA1509_39875, RNA815_14684}
100. MligTC455_47600 263 5.48 Mlig455_031414

Neo: -

Age: -

Region-enriched R2: 2.961/0.01561

NRXN1 1.744 - - - 0.980 0.764 - Mlig455_031414 {REF} {Length: 4843} {Pfam: Laminin G domain [PF02210.26, score=235.7]; Laminin G domain [PF00054.25, score=191.1]; Syndecan domain [PF01034.22, score=26.0]; Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=22.3]; EGF-like domain [PF00008.29, score=19.4]} {Human: ENSG00000179915, NRXN1, neurexin 1, [RH, Score=379, Expect=3e-109]} {Mouse: ENSMUSG00000024109, Nrxn1, neurexin I, [Score=387, Expect=1e-112]} {Dmel: FBgn0038975, Nrx-1, Neurexin 1, [Score=313, Expect=5e-87]} {Celegans: WBGene00007799, nrx-1, NRX-1 beta isoform; NeuReXin related, [Score=179, Expect=2e-45]} {Smed: dd_Smed_v6_13697_0_1, dd_Smed_v6_13697_0_1, [Score=349, Expect=9e-101]} {RNA1509_55888} {RNA1310_9438.1} {RNA815_24775.1}

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