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Results for MligTC455_38178

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_38178 19 0.39 Mlig455_025460

Neo: -

Age: -

 SIX4 Mlig455_025460 {REF} {Length: 2329} {Pfam: Transcriptional regulator, SIX1, N-terminal SD domain [PF16878.7, score=141.7]; Homeodomain [PF00046.31, score=57.9]; Homeobox KN domain [PF05920.13, score=40.9]} {Human: ENSG00000100625, SIX4, SIX homeobox 4, [RH, Score=271, Expect=6e-84]} {Mouse: ENSMUSG00000034460, Six4, sine oculis-related homeobox 4, [RH, Score=270, Expect=1e-83]} {Dmel: FBgn0027364, Six4, [RH, Score=254, Expect=2e-81]} {Celegans: WBGene00000454, ceh-33, Homeobox protein ceh-33, [Score=202, Expect=3e-63]} {Smed: dd_Smed_v6_37930_0_1, dd_Smed_v6_37930_0_1, [RH, Score=244, Expect=7e-79]}

Cumulative graph for MligTC455_38178

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 1.508 0.796 1.00000 1.00000
RegionR2 3.058 0.796 0.80001 1.00000
RegionR3 0.517 0.796 0.73851 1.00000
RegionR4 1.44 0.796 0.23365 0.52763
RegionR5 -2.067 0.796 1.00000 1.00000
RegionR6 -2.882 0.796 1.00000 1.00000
RegionR7 -1.494 0.796 1.00000 1.00000
RegionR8 -0.08 0.796 1.00000 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -4.335 0.796 1.00000 1.00000
RegenerationR2 -3.365 0.796 0.04873 0.36466
RegenerationR3 -2.818 0.796 0.05673 0.40862
RegenerationR4 -3.113 0.796 0.04790 0.35277
RegenerationR5 -0.034 0.796 0.88744 1.00000
RegenerationR6 -1.511 0.796 0.99993 1.00000
RegenerationBL -2.784 0.796 0.99993 1.00000
RegenerationTP -1.805 0.796 0.99993 1.00000


Genes with expression patterns similar to MligTC455_38178

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_38178 19 0.39 Mlig455_025460

Neo: -

Age: -

 SIX4 3 1.000 - 1.000 - 1.000 - Mlig455_025460 {REF} {Length: 2329} {Pfam: Transcriptional regulator, SIX1, N-terminal SD domain [PF16878.7, score=141.7]; Homeodomain [PF00046.31, score=57.9]; Homeobox KN domain [PF05920.13, score=40.9]} {Human: ENSG00000100625, SIX4, SIX homeobox 4, [RH, Score=271, Expect=6e-84]} {Mouse: ENSMUSG00000034460, Six4, sine oculis-related homeobox 4, [RH, Score=270, Expect=1e-83]} {Dmel: FBgn0027364, Six4, [RH, Score=254, Expect=2e-81]} {Celegans: WBGene00000454, ceh-33, Homeobox protein ceh-33, [Score=202, Expect=3e-63]} {Smed: dd_Smed_v6_37930_0_1, dd_Smed_v6_37930_0_1, [RH, Score=244, Expect=7e-79]}
2. MligTC455_38682 102 2.12 Mlig455_039641

Neo: -

Age: -

Region-enriched R2: 6.138/0.02363

 SLC18A3 2.689 0.993 - 0.785 - 0.911 - Mlig455_039641 {REF} {Length: 3925} {Pfam: Major Facilitator Superfamily [PF07690.18, score=147.1]; Sugar (and other) transporter [PF00083.26, score=29.0]; LacY proton/sugar symporter [PF01306.21, score=20.2]} {Human: ENSG00000187714, SLC18A3, solute carrier family 18 member A3, [RH, Score=469, Expect=9e-161]} {Mouse: ENSMUSG00000100241, Slc18a3, solute carrier family 18 (vesicular monoamine), member 3, [RH, Score=469, Expect=1e-160]} {Dmel: FBgn0270928, VAChT, Vesicular acetylcholine transporter, [RH, Score=513, Expect=2e-177]} {Celegans: WBGene00006756, unc-17, Vesicular acetylcholine transporter unc-17, [RH, Score=486, Expect=2e-167]} {Smed: dd_Smed_v6_11630_0_1, dd_Smed_v6_11630_0_1, [RH, Score=563, Expect=0.0]} {RNA1310_28397} {RNA815_32284.1}
3. MligTC455_31104 22 0.46 Mlig455_040032, Mlig455_070983

Neo: -

Age: -

 SYT17 2.68 0.965 - 0.959 - 0.756 -

Mlig455_040032 {REF} {Length: 2712} {Pfam: C2 domain [PF00168.32, score=79.2]} {Human: ENSG00000103528, SYT17, synaptotagmin 17, [Score=127, Expect=1e-30]} {Mouse: ENSMUSG00000058420, Syt17, synaptotagmin XVII, [Score=126, Expect=1e-30]} {Dmel: FBgn0028400, Syt4, Synaptotagmin 4, [Score=88.6, Expect=2e-18]} {Celegans: WBGene00004922, snt-2, Synaptotagmin 2, [Score=94.0, Expect=1e-20]} {Smed: dd_Smed_v6_19213_0_1, dd_Smed_v6_19213_0_1, [Score=96.7, Expect=3e-21]} {RNA1310_17303}

Mlig455_070983 {REF} {Length: 1947} {Pfam: C2 domain [PF00168.32, score=79.2]} {Human: ENSG00000103528, SYT17, synaptotagmin 17, [Score=127, Expect=1e-30]} {Mouse: ENSMUSG00000058420, Syt17, synaptotagmin XVII, [Score=126, Expect=1e-30]} {Dmel: FBgn0028400, Syt4, Synaptotagmin 4, [Score=88.6, Expect=2e-18]} {Celegans: WBGene00004922, snt-2, Synaptotagmin 2, [Score=94.0, Expect=1e-20]} {Smed: dd_Smed_v6_19213_0_1, dd_Smed_v6_19213_0_1, [Score=96.7, Expect=3e-21]} {RNA1310_17303}
4. MligTC455_13421 86 1.79 Mlig455_036504, Mlig455_069144

Neo: -

Age: -

 SYT17 2.66 0.977 - 0.947 - 0.736 -

Mlig455_036504 {REF} {Length: 2390} {Pfam: C2 domain [PF00168.32, score=84.3]} {Human: ENSG00000103528, SYT17, synaptotagmin 17, [Score=137, Expect=5e-35]} {Mouse: ENSMUSG00000058420, Syt17, synaptotagmin XVII, [Score=137, Expect=6e-35]} {Dmel: FBgn0028400, Syt4, Synaptotagmin 4, [Score=101, Expect=1e-22]} {Celegans: WBGene00004922, snt-2, Synaptotagmin 2, [Score=105, Expect=2e-24]} {Smed: dd_Smed_v6_19213_0_1, dd_Smed_v6_19213_0_1, [RH, Score=124, Expect=2e-30]} {RNA1310_17303} {RNA815_33031}

Mlig455_069144 {REF} {Length: 1355} {Pfam: C2 domain [PF00168.32, score=84.3]} {Human: ENSG00000103528, SYT17, synaptotagmin 17, [Score=137, Expect=5e-35]} {Mouse: ENSMUSG00000058420, Syt17, synaptotagmin XVII, [Score=137, Expect=6e-35]} {Dmel: FBgn0028400, Syt4, Synaptotagmin 4, [Score=101, Expect=1e-22]} {Celegans: WBGene00004922, snt-2, Synaptotagmin 2, [Score=105, Expect=2e-24]} {Smed: dd_Smed_v6_19213_0_1, dd_Smed_v6_19213_0_1, [RH, Score=124, Expect=2e-30]} {RNA1310_17303} {RNA815_33031}
5. MligTC455_54338 49 1.02 Mlig455_056485

Neo: -

Age: Up-Down-Down

 PKDREJ 2.656 0.990 - 0.783 - 0.883 - Mlig455_056485 {REF} {Length: 11174} {Pfam: Polycystin cation channel [PF08016.14, score=290.0]; REJ domain [PF02010.17, score=90.7]; PLAT/LH2 domain [PF01477.25, score=67.3]; PKD domain [PF00801.22, score=47.7]; Ion transport protein [PF00520.33, score=40.1]; PKD domain [PF18911.2, score=29.8]; GPCR proteolysis site, GPS, motif [PF01825.23, score=27.4]; WSC domain [PF01822.21, score=27.0]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=280, Expect=1e-74]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=307, Expect=8e-83]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=151, Expect=3e-36]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [RH, Score=302, Expect=1e-81]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [RH, Score=1844, Expect=0.0]} {RNA1509_16432} {RNA1310_1236} {RNA815_2411}
6. MligTC455_31853 516 10.74 Mlig455_014495, Mlig455_014514, Mlig455_054434

Neo: -

Age: -

 2.628 0.948 - 0.729 - 0.951 -

Mlig455_014495 {REF} {Length: 3100} {RNA1509_20117} {RNA1310_5956.1, RNA1509_20117} {RNA1509_20117, RNA815_18508}

Mlig455_014514 {REF} {Length: 3051} {Smed: dd_Smed_v6_3795_0_2, dd_Smed_v6_3795_0_2, [RH, Score=89.7, Expect=2e-19]} {RNA1509_20117} {RNA1310_5956.1} {RNA815_18508}

Mlig455_054434 {REF} {Length: 4026} {Pfam: Late embryogenesis abundant protein [PF03242.15, score=21.0]} {Smed: dd_Smed_v6_3795_0_2, dd_Smed_v6_3795_0_2, [RH, Score=89.4, Expect=2e-20]} {RNA1509_20117} {RNA1310_8165} {RNA815_23492}
7. MligTC455_34369 112 2.34 Mlig455_015308, Mlig455_015354, Mlig455_036248, Mlig455_068737, Mlig455_070110

Neo: -

Age: Up-Down-Up

Region-enriched R2: 5.462/0.00546

 2.623 0.974 - 0.705 - 0.944 -

Mlig455_015308 {REF} {Length: 1459} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=63.9]} {RNA1310_34740} {RNA815_15663}

Mlig455_015354 {REF} {Length: 1446} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=66.3]; Sialidase, N-terminal domain [PF02973.18, score=18.5]} {RNA1310_34740} {RNA815_15663}

Mlig455_036248 {REF} {Length: 2111} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=120.9]; Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=28.5]; PAN domain [PF00024.28, score=19.9]} {RNA1509_45496} {RNA1310_2539.1} {RNA815_252.1}

Mlig455_068737 {REF} {Length: 1096} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=68.3]; Sialidase, N-terminal domain [PF02973.18, score=19.9]} {RNA1310_34740} {RNA815_37905}

Mlig455_070110 {REF} {Length: 1340} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=109.6]} {RNA1509_32599} {RNA1310_1659} {RNA815_252.1}
8. MligTC455_39481 461 9.6 Mlig455_056703, Mlig455_060318

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.222

 ANGPTL1 2.615 0.961 - 0.767 - 0.887 -

Mlig455_056703 {REF} {Length: 1114} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=79.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=89.4, Expect=1e-19]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=85.1, Expect=3e-18]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=91.3, Expect=2e-20]} {Dmel: FBgn0033312, CG8642, [Score=82.4, Expect=1e-17]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=76.3, Expect=1e-15]} {RNA1310_31288} {RNA815_20497.1}

Mlig455_060318 {REF} {Length: 1175} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=112.7]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=106, Expect=2e-25]; ENSG00000171819, ANGPTL7, angiopoietin like 7, [Score=105, Expect=6e-26]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=109, Expect=1e-26]} {Dmel: FBgn0034160, CG5550, [Score=96.3, Expect=2e-23]} {Celegans: WBGene00016769, C49C8.5, [Score=47.0, Expect=9e-06]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=88.2, Expect=2e-19]} {RNA1310_31288} {RNA815_20497.1}
9. MligTC455_13963 31 0.64 Mlig455_052027

Neo: -

Age: Down-Up-Down

 2.61 0.984 - 0.720 - 0.906 - Mlig455_052027 {REF} {Length: 1717} {RNA1509_48973} {RNA1310_34931} {RNA815_59614}
10. MligTC455_18099 24 0.51 Mlig455_036525

Neo: -

Age: -

 PPA1 2.607 0.984 - 0.741 - 0.882 - Mlig455_036525 {REF} {Length: 1911} {Pfam: Inorganic pyrophosphatase [PF00719.21, score=181.8]} {Human: ENSG00000180817, PPA1, pyrophosphatase (inorganic) 1, [Score=304, Expect=2e-103]; ENSG00000138777, PPA2, pyrophosphatase (inorganic) 2, [Score=295, Expect=4e-99]} {Mouse: ENSMUSG00000020089, Ppa1, pyrophosphatase (inorganic) 1, [Score=307, Expect=9e-105]} {Dmel: FBgn0016687, Nurf-38, Nucleosome remodeling factor - 38kD, [Score=303, Expect=2e-103]} {Celegans: WBGene00008149, pyp-1, Probable inorganic pyrophosphatase 1, [Score=315, Expect=5e-108]} {Smed: dd_Smed_v6_625_0_1, dd_Smed_v6_625_0_1, [Score=290, Expect=2e-98]} {RNA1310_57333.1} {RNA815_22340}
11. MligTC455_31933 105 2.18 Mlig455_062083

Neo: -

Age: -

 ANGPTL1 2.605 0.995 - 0.711 - 0.899 - Mlig455_062083 {REF} {Length: 1024} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=156.7]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=135, Expect=7e-36]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=132, Expect=2e-34]; ENSG00000101280, ANGPT4, angiopoietin 4, [Score=132, Expect=9e-35]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=137, Expect=1e-36]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=132, Expect=4e-35]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=131, Expect=1e-34]} {Dmel: FBgn0034160, CG5550, [Score=130, Expect=2e-36]} {Celegans: WBGene00020516, T15B7.1, [Score=73.9, Expect=9e-15]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=126, Expect=2e-32]} {RNA1509_14033} {RNA1310_32107.2} {RNA815_17173.3}
12. MligTC455_41396 187 3.9 Mlig455_012937, Mlig455_031470

Neo: -

Age: -

Region-enriched R2: 4.167/0.01146

 2.602 0.952 - 0.721 - 0.929 -

Mlig455_012937 {REF} {Length: 1911} {Smed: dd_Smed_v6_11196_0_1, dd_Smed_v6_11196_0_1, [Score=46.6, Expect=1e-06]} {RNA1509_16138} {RNA1310_24329} {RNA815_11818}

Mlig455_031470 {REF} {Length: 1745} {Dmel: FBgn0083971, CG34135, [RH, Score=60.1, Expect=1e-10]} {Smed: dd_Smed_v6_11196_0_1, dd_Smed_v6_11196_0_1, [RH, Score=96.3, Expect=3e-23]} {RNA1509_16138} {RNA1310_24329} {RNA815_11818}
13. MligTC455_33039 312 6.51 Mlig455_032494

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.545/0.00267

 PKDREJ 2.602 0.976 - 0.722 - 0.904 - Mlig455_032494 {REF} {Length: 11952} {Pfam: Polycystin cation channel [PF08016.14, score=289.9]; REJ domain [PF02010.17, score=90.4]; PLAT/LH2 domain [PF01477.25, score=68.4]; PKD domain [PF00801.22, score=57.9]; PKD domain [PF18911.2, score=36.7]; Ion transport protein [PF00520.33, score=36.3]; GPCR proteolysis site, GPS, motif [PF01825.23, score=30.0]; WSC domain [PF01822.21, score=23.3]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=267, Expect=1e-70]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=292, Expect=3e-78]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=136, Expect=2e-31]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [RH, Score=297, Expect=4e-80]} {Smed: dd_Smed_v6_15525_0_1, dd_Smed_v6_15525_0_1, [Score=1504, Expect=0.0]} {RNA1509_3444} {RNA1310_89} {RNA815_1814}
14. MligTC455_46430 62 1.29 Mlig455_057117, Mlig455_069301

Neo: -

Age: -

 GUCY2F 2.601 0.978 - 0.772 - 0.851 -

Mlig455_057117 {REF} {Length: 2651} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=196.0]; Nitrate and nitrite sensing [PF08376.12, score=82.5]; Heme NO binding associated [PF07701.16, score=28.2]} {Human: ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=247, Expect=9e-70]; ENSG00000169418, NPR1, natriuretic peptide receptor 1, [Score=242, Expect=3e-68]; ENSG00000159899, NPR2, natriuretic peptide receptor 2, [Score=238, Expect=5e-67]} {Mouse: ENSMUSG00000042282, Gucy2f, guanylate cyclase 2f, [Score=246, Expect=7e-70]; ENSMUSG00000027931, Npr1, natriuretic peptide receptor 1, [Score=242, Expect=2e-68]; ENSMUSG00000020890, Gucy2e, guanylate cyclase 2e, [Score=241, Expect=7e-68]; ENSMUSG00000028469, Npr2, natriuretic peptide receptor 2, [Score=239, Expect=3e-67]} {Dmel: FBgn0053958, CG33958, [Score=266, Expect=4e-79]} {Celegans: WBGene00001547, gcy-22, Receptor-type guanylate cyclase gcy-22, [Score=235, Expect=3e-66]} {Smed: dd_Smed_v6_14331_0_1, dd_Smed_v6_14331_0_1, [Score=238, Expect=4e-67]} {RNA1509_38781} {RNA1310_35456} {RNA815_22108}

Mlig455_069301 {REF} {Length: 2370} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=178.1]; Nitrate and nitrite sensing [PF08376.12, score=82.3]; Heme NO binding associated [PF07701.16, score=28.0]} {Human: ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=232, Expect=2e-64]} {Mouse: ENSMUSG00000042282, Gucy2f, guanylate cyclase 2f, [Score=232, Expect=1e-64]; ENSMUSG00000020890, Gucy2e, guanylate cyclase 2e, [Score=225, Expect=5e-62]} {Dmel: FBgn0053958, CG33958, [Score=250, Expect=5e-73]} {Celegans: WBGene00001547, gcy-22, Receptor-type guanylate cyclase gcy-22, [Score=223, Expect=1e-61]} {Smed: dd_Smed_v6_14331_0_1, dd_Smed_v6_14331_0_1, [Score=221, Expect=4e-61]} {RNA1509_38781} {RNA1310_35456} {RNA815_24181}
15. MligTC455_15949 37 0.76 Mlig455_059880

Neo: -

Age: -

 2.599 0.995 - 0.839 - 0.765 - Mlig455_059880 {REF} {Length: 1226} {Pfam: Lectin C-type domain [PF00059.23, score=39.5]} {Dmel: FBgn0031373, CG15358, [Score=52.8, Expect=4e-08]} {RNA1310_120903}
16. MligTC455_40707 15 0.31 Mlig455_033559, Mlig455_067009

Neo: -

Age: -

 GRIK2 2.598 0.995 - 0.740 - 0.863 -

Mlig455_033559 {REF} {Length: 3723} {tRNA: Val(CAC),pseudo, score=30.0} {Pfam: Ligand-gated ion channel [PF00060.28, score=144.7]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=101.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=66.3]; Receptor family ligand binding region [PF01094.30, score=22.9]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=325, Expect=4e-97]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=318, Expect=2e-94]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=309, Expect=8e-91]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=323, Expect=2e-96]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=316, Expect=2e-93]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=310, Expect=3e-92]} {Dmel: FBgn0038837, CG3822, [Score=292, Expect=2e-85]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=252, Expect=8e-71]} {Smed: dd_Smed_v6_14655_0_1, dd_Smed_v6_14655_0_1, [Score=357, Expect=2e-108]} {RNA1310_11982.1} {RNA815_20096}

Mlig455_067009 {REF} {Length: 2583} {Pfam: Ligand-gated ion channel [PF00060.28, score=121.5]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=101.3]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=46.3]; Receptor family ligand binding region [PF01094.30, score=22.3]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=267, Expect=1e-76]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=265, Expect=2e-75]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=260, Expect=7e-74]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=267, Expect=1e-76]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=262, Expect=1e-74]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=259, Expect=2e-74]} {Dmel: FBgn0038837, CG3822, [Score=234, Expect=2e-65]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=208, Expect=2e-56]} {Smed: dd_Smed_v6_14655_0_1, dd_Smed_v6_14655_0_1, [Score=281, Expect=2e-81]} {RNA1310_11982.1} {RNA815_20096}
17. MligTC455_52570 71 1.49 Mlig455_066071

Neo: -

Age: Up-Down-Up

 2.595 0.984 - 0.703 - 0.908 - Mlig455_066071 {REF} {Length: 2575} {Pfam: Hemingway/CFA97 [PF13879.8, score=54.6]; Annexin [PF00191.22, score=26.1]} {Mouse: ENSMUSG00000090336, Cfap97d2, CFAP97 domain containing 2, [Score=46.6, Expect=3e-06]} {Smed: dd_Smed_v6_2676_0_1, dd_Smed_v6_2676_0_1, [Score=70.1, Expect=2e-13]} {RNA1310_29320.1} {RNA815_54680}
18. MligTC455_37838 40 0.83 Mlig455_012885

Neo: -

Age: Up-Down-Down

 PKDREJ 2.583 0.987 - 0.777 - 0.819 - Mlig455_012885 {REF} {Length: 13341} {Pfam: Polycystin cation channel [PF08016.14, score=221.2]; REJ domain [PF02010.17, score=52.8]; PLAT/LH2 domain [PF01477.25, score=27.5]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=184, Expect=7e-46]} {Mouse: ENSMUSG00000052496, Pkdrej, polycystin (PKD) family receptor for egg jelly, [Score=186, Expect=7e-47]; ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=178, Expect=3e-44]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=110, Expect=6e-24]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [Score=121, Expect=3e-27]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [Score=260, Expect=1e-69]} {RNA1509_38015} {RNA1310_23208, RNA1509_38015} {RNA1509_38015, RNA815_31966}
19. MligTC455_50288 118 2.47 Mlig455_059182

Neo: -

Age: Up-Down-Down

 2.581 0.900 - 0.728 - 0.953 - Mlig455_059182 {REF} {Length: 3438} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=42.6]; Lectin C-type domain [PF00059.23, score=23.6]} {Smed: dd_Smed_v6_41498_0_1, dd_Smed_v6_41498_0_1, [RH, Score=189, Expect=3e-53]} {RNA1509_45950, RNA1509_54781} {RNA1310_10757.1, RNA1509_45950, RNA1509_54781} {RNA1509_45950, RNA1509_54781, RNA815_5369}
20. MligTC455_39222 213 4.44 Mlig455_064653, Mlig455_064686

Neo: -

Age: -

Region-enriched R2: 4.317/0.00597

 2.579 0.971 - 0.734 - 0.874 -

Mlig455_064653 {REF} {Length: 2836} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=56.8]} {Mouse: ENSMUSG00000039079, Trhr2, thyrotropin releasing hormone receptor 2, [Score=58.9, Expect=6e-09]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [Score=73.6, Expect=8e-14]} {Celegans: WBGene00008885, F16C3.1, [Score=51.2, Expect=7e-07]} {Smed: dd_Smed_v6_13282_0_1, dd_Smed_v6_13282_0_1, [RH, Score=219, Expect=1e-66]} {RNA1509_56255} {RNA1310_13407} {RNA815_38407}

Mlig455_064686 {REF} {Length: 3820} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=56.8]} {Mouse: ENSMUSG00000039079, Trhr2, thyrotropin releasing hormone receptor 2, [Score=58.5, Expect=6e-09]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [Score=73.6, Expect=8e-14]} {Celegans: WBGene00008885, F16C3.1, [Score=51.2, Expect=8e-07]} {Smed: dd_Smed_v6_13282_0_1, dd_Smed_v6_13282_0_1, [RH, Score=219, Expect=1e-66]} {RNA1509_50956} {RNA1310_13407} {RNA815_38407}
21. MligTC455_50253 44 0.92 Mlig455_031495

Neo: -

Age: -

 GABRB2 2.573 0.980 - 0.763 - 0.830 - Mlig455_031495 {REF} {Length: 2129} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=58.3]} {Human: ENSG00000145864, GABRB2, gamma-aminobutyric acid type A receptor beta2 subunit, [Score=71.2, Expect=6e-14]} {Mouse: ENSMUSG00000007653, Gabrb2, gamma-aminobutyric acid (GABA) A receptor, subunit beta 2, [Score=67.8, Expect=1e-12]; ENSMUSG00000029212, Gabrb1, gamma-aminobutyric acid (GABA) A receptor, subunit beta 1, [Score=67.4, Expect=1e-12]} {Dmel: FBgn0024963, GluClalpha, [Score=54.3, Expect=3e-08]} {Celegans: WBGene00001594, glc-4, Glutamate-gated ChLoride channel, [Score=66.6, Expect=2e-12]} {Smed: dd_Smed_v6_15331_0_1, dd_Smed_v6_15331_0_1, [Score=70.1, Expect=9e-14]} {RNA1310_46931} {RNA815_25428}
22. MligTC455_12183 53 1.11 Mlig455_004166, Mlig455_004190

Neo: -

Age: -

Region-enriched R2: 4.930/0.01881

 2.572 0.975 - 0.868 - 0.729 -

Mlig455_004166 {REF} {Length: 2818} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=57.4]; Serpentine type 7TM GPCR chemoreceptor Srbc [PF10316.11, score=29.1]} {Celegans: WBGene00019019, frpr-10, FMRFamide Peptide Receptor family, [Score=55.5, Expect=1e-08]} {Smed: dd_Smed_v6_70862_0_1, dd_Smed_v6_70862_0_1, [Score=60.8, Expect=8e-12]} {RNA1310_64973} {RNA815_58453}

Mlig455_004190 {REF} {Length: 2742} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=56.7]; Serpentine type 7TM GPCR chemoreceptor Srbc [PF10316.11, score=28.6]} {Celegans: WBGene00019019, frpr-10, FMRFamide Peptide Receptor family, [Score=56.2, Expect=1e-08]} {Smed: dd_Smed_v6_70862_0_1, dd_Smed_v6_70862_0_1, [Score=60.8, Expect=1e-11]} {RNA1310_62602} {RNA815_58453}
23. MligTC455_43390 28 0.59 Mlig455_064273

Neo: -

Age: Down-Up-Down

 PRKAR2A 2.561 0.984 - 0.843 - 0.734 - Mlig455_064273 {REF} {Length: 2394} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=122.5]; Regulatory subunit of type II PKA R-subunit [PF02197.19, score=40.5]} {Human: ENSG00000114302, PRKAR2A, protein kinase cAMP-dependent type II regulatory subunit alpha, [Score=305, Expect=2e-100]; ENSG00000005249, PRKAR2B, protein kinase cAMP-dependent type II regulatory subunit beta, [Score=296, Expect=8e-97]; ENSG00000284096, PRKAR2B, protein kinase cAMP-dependent type II regulatory subunit beta, [Score=296, Expect=8e-97]} {Mouse: ENSMUSG00000032601, Prkar2a, protein kinase, cAMP dependent regulatory, type II alpha, [Score=314, Expect=6e-104]} {Dmel: FBgn0022382, Pka-R2, Protein kinase, cAMP-dependent, regulatory subunit type 2, [Score=335, Expect=1e-112]} {Celegans: WBGene00002190, kin-2, cAMP-dependent protein kinase regulatory subunit, [Score=219, Expect=2e-68]} {Smed: dd_Smed_v6_4188_0_1, dd_Smed_v6_4188_0_1, [Score=335, Expect=5e-113]} {RNA1509_34470} {RNA1310_27777} {RNA815_5628}
24. MligTC455_43979 188 3.92 Mlig455_000082, Mlig455_063749

Neo: -

Age: -

 GHSR 2.561 0.984 - 0.785 - 0.792 -

Mlig455_000082 {REF} {Length: 1342} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=53.1]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=18.2]} {Human: ENSG00000121853, GHSR, growth hormone secretagogue receptor, [Score=52.0, Expect=7e-07]} {Mouse: ENSMUSG00000051136, Ghsr, growth hormone secretagogue receptor, [Score=50.4, Expect=2e-06]} {Celegans: WBGene00018798, gnrr-1, GoNadotropin-Releasing hormone Receptor (GnRHR) related, [Score=48.9, Expect=3e-06]} {Smed: dd_Smed_v6_60346_0_1, dd_Smed_v6_60346_0_1, [RH, Score=160, Expect=9e-47]} {RNA1310_30553}

Mlig455_063749 {REF} {Length: 1323} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=48.3]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=20.4]} {Smed: dd_Smed_v6_60346_0_1, dd_Smed_v6_60346_0_1, [RH, Score=157, Expect=1e-45]} {RNA1310_30553}
25. MligTC455_52120 179 3.73 Mlig455_024423, Mlig455_024577

Neo: -

Age: Down-Up-Down

Region-enriched R2: 4.068/0.01755

 POU4F3 2.553 0.954 - 0.735 - 0.864 -

Mlig455_024423 {REF} {Length: 1288} {TRANSSPLICED} {Pfam: Pou domain - N-terminal to homeobox domain [PF00157.19, score=104.8]; Homeodomain [PF00046.31, score=60.9]} {Human: ENSG00000091010, POU4F3, POU class 4 homeobox 3, [Score=212, Expect=1e-65]; ENSG00000152192, POU4F1, POU class 4 homeobox 1, [Score=211, Expect=2e-64]} {Mouse: ENSMUSG00000024497, Pou4f3, POU domain, class 4, transcription factor 3, [Score=212, Expect=7e-66]; ENSMUSG00000048349, Pou4f1, POU domain, class 4, transcription factor 1, [Score=211, Expect=2e-64]} {Dmel: FBgn0000028, acj6, abnormal chemosensory jump 6, [Score=209, Expect=2e-64]} {Celegans: WBGene00006818, unc-86, Transcription factor unc-86, [Score=188, Expect=4e-57]} {Smed: dd_Smed_v6_30562_0_1, dd_Smed_v6_30562_0_1, [Score=208, Expect=2e-64]} {RNA1509_57422} {RNA1310_23131} {RNA815_34447}

Mlig455_024577 {REF} {Length: 1325} {TRANSSPLICED} {Pfam: Pou domain - N-terminal to homeobox domain [PF00157.19, score=104.8]; Homeodomain [PF00046.31, score=60.9]} {Human: ENSG00000091010, POU4F3, POU class 4 homeobox 3, [Score=212, Expect=1e-65]; ENSG00000152192, POU4F1, POU class 4 homeobox 1, [Score=211, Expect=2e-64]} {Mouse: ENSMUSG00000024497, Pou4f3, POU domain, class 4, transcription factor 3, [Score=212, Expect=7e-66]; ENSMUSG00000048349, Pou4f1, POU domain, class 4, transcription factor 1, [Score=211, Expect=2e-64]} {Dmel: FBgn0000028, acj6, abnormal chemosensory jump 6, [Score=209, Expect=2e-64]} {Celegans: WBGene00006818, unc-86, Transcription factor unc-86, [Score=188, Expect=4e-57]} {Smed: dd_Smed_v6_30562_0_1, dd_Smed_v6_30562_0_1, [Score=208, Expect=2e-64]} {RNA1509_57422} {RNA1310_23131} {RNA815_34447}
26. MligTC455_32644 41 0.86 Mlig455_043770, Mlig455_043786

Neo: -

Age: -

Region-enriched R2: 6.705/0.00336

 2.552 0.979 - 0.798 - 0.775 -

Mlig455_043770 {REF} {Length: 1011} {Pfam: PAN domain [PF00024.28, score=19.3]} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=60.8, Expect=3e-11]} {RNA1509_35604} {RNA1310_57814} {RNA815_29718}

Mlig455_043786 {REF} {Length: 1348} {Pfam: PAN domain [PF00024.28, score=19.3]} {RNA1509_35604} {RNA1310_34182} {RNA815_29718}
27. MligTC455_18748 104 2.17 Mlig455_024985, Mlig455_024999

Neo: -

Age: -

Region-enriched R2: 6.002/0.00016
Region-enriched R4: 3.433/0.02745

 GRIK4 2.548 0.955 - 0.730 - 0.863 -

Mlig455_024985 {REF} {Length: 1514} {Pfam: Ligand-gated ion channel [PF00060.28, score=76.7]; Receptor family ligand binding region [PF01094.30, score=31.5]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=20.6]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=122, Expect=1e-27]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=124, Expect=1e-28]} {Dmel: FBgn0038837, CG3822, [Score=120, Expect=1e-27]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=99.0, Expect=5e-21]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=196, Expect=2e-55]} {RNA1509_35538} {RNA1310_47299} {RNA815_38321}

Mlig455_024999 {REF} {Length: 3567} {Pfam: Ligand-gated ion channel [PF00060.28, score=76.7]; Receptor family ligand binding region [PF01094.30, score=31.5]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=20.6]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=122, Expect=1e-27]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=124, Expect=1e-28]} {Dmel: FBgn0038837, CG3822, [Score=120, Expect=1e-27]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=99.0, Expect=5e-21]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=196, Expect=2e-55]} {RNA1509_35538} {RNA1310_7578, RNA1509_35538} {RNA1509_35538, RNA815_4987}
28. MligTC455_39890 162 3.37 Mlig455_047281, Mlig455_047331, Mlig455_069333

Neo: -

Age: -

Region-enriched R2: 6.097/0.00148

 PLSCR1 2.547 0.982 - 0.802 - 0.763 -

Mlig455_047281 {REF} {Length: 1404} {Pfam: Scramblase [PF03803.17, score=248.1]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=225, Expect=4e-72]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=227, Expect=5e-73]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=222, Expect=3e-71]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=223, Expect=6e-73]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=194, Expect=2e-61]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [RH, Score=306, Expect=1e-104]} {RNA1310_29769} {RNA815_41335}

Mlig455_047331 {REF} {Length: 1395} {Pfam: Scramblase [PF03803.17, score=248.1]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=225, Expect=4e-72]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=227, Expect=5e-73]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=222, Expect=3e-71]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=223, Expect=6e-73]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=194, Expect=2e-61]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [RH, Score=306, Expect=1e-104]} {RNA1310_29769} {RNA815_41335}

Mlig455_069333 {REF} {Length: 1416} {Pfam: Scramblase [PF03803.17, score=248.7]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=226, Expect=1e-72]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=228, Expect=2e-73]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=223, Expect=1e-71]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=224, Expect=2e-73]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=194, Expect=4e-61]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [RH, Score=304, Expect=2e-103]} {RNA1310_29769} {RNA815_41335}
29. MligTC455_50355 38 0.79 Mlig455_057631

Neo: -

Age: -

Region-enriched R2: 7.639/0.01837

 2.5 0.983 - 0.773 - 0.744 - Mlig455_057631 {REF} {Length: 1003} {Pfam: WSC domain [PF01822.21, score=45.2]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=47.4, Expect=6e-06]} {RNA1310_44307} {RNA815_33128}
30. MligTC455_47420 218 4.54 Mlig455_017159, Mlig455_048110

Neo: -

Age: -

Region-specific R2: 6.469

Region-enriched R2: 5.851/0.00135

 2.498 0.969 - 0.726 - 0.803 -

Mlig455_017159 {REF} {Length: 1062} {RNA1509_35349} {RNA1310_81586}

Mlig455_048110 {REF} {Length: 527} {RNA1310_81586}
31. MligTC455_12512 80 1.68 Mlig455_017689

Neo: -

Age: -

 2.497 0.984 - 0.755 - 0.758 - Mlig455_017689 {REF} {Length: 934} {RNA1310_37507} {RNA815_32171}
32. MligTC455_35773 89 1.86 Mlig455_064449, Mlig455_064456

Neo: -

Age: -

Region-enriched R2: 5.198/0.00725

 NANP 2.492 0.972 - 0.706 - 0.814 -

Mlig455_064449 {REF} {Length: 503} {NoTransDecoderORF} {RNA1310_53432.2}

Mlig455_064456 {REF} {Length: 3122} {Pfam: Haloacid dehalogenase-like hydrolase [PF13419.8, score=56.3]; haloacid dehalogenase-like hydrolase [PF00702.28, score=55.3]; HAD-hyrolase-like [PF13242.8, score=44.6]} {Human: ENSG00000170191, NANP, N-acetylneuraminic acid phosphatase, [RH, Score=47.4, Expect=8e-06]} {Mouse: ENSMUSG00000053916, Nanp, N-acetylneuraminic acid phosphatase, [RH, Score=48.5, Expect=2e-06]} {Celegans: WBGene00018465, F45E1.4, [RH, Score=147, Expect=4e-43]} {Smed: dd_Smed_v6_2813_0_3, dd_Smed_v6_2813_0_3, [Score=174, Expect=2e-50]} {RNA1310_59243} {RNA815_62364}
33. MligTC455_50844 224 4.67 Mlig455_018511

Neo: -

Age: Down-Up-Up

Region-enriched R2: 4.591/0.00005

 SSUH2 2.492 0.958 - 0.752 - 0.782 - Mlig455_018511 {REF} {Length: 1843} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=120, Expect=2e-29]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=95.5, Expect=3e-21]} {RNA1509_39980} {RNA1310_60742, RNA1509_39980} {RNA1509_39980, RNA815_28938}
34. MligTC455_51386 763 15.89 Mlig455_041336, Mlig455_056222

Neo: -

Age: -

Region-enriched R2: 3.643/0.00016

 HPGDS 2.484 0.971 - 0.726 - 0.787 -

Mlig455_041336 {REF} {Length: 1363} {Pfam: Glutathione S-transferase, C-terminal domain [PF14497.8, score=46.9]; Glutathione S-transferase, N-terminal domain [PF02798.22, score=34.8]; Glutathione S-transferase, N-terminal domain [PF13409.8, score=23.3]; Glutathione S-transferase, N-terminal domain [PF13417.8, score=22.4]} {Human: ENSG00000163106, HPGDS, hematopoietic prostaglandin D synthase, [Score=74.7, Expect=2e-15]} {Mouse: ENSMUSG00000029919, Hpgds, hematopoietic prostaglandin D synthase, [Score=82.4, Expect=2e-18]} {Celegans: WBGene00001756, gst-8, Probable glutathione S-transferase 8, [Score=92.8, Expect=2e-22]} {Smed: dd_Smed_v6_1206_0_1, dd_Smed_v6_1206_0_1, [Score=79.0, Expect=2e-17]} {RNA1509_56224} {RNA1310_31890.2} {RNA815_14778}

Mlig455_056222 {REF} {Length: 1343} {Pfam: Glutathione S-transferase, C-terminal domain [PF14497.8, score=62.1]; Glutathione S-transferase, N-terminal domain [PF02798.22, score=34.8]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=31.1]; Glutathione S-transferase, N-terminal domain [PF13409.8, score=23.4]; Glutathione S-transferase, N-terminal domain [PF13417.8, score=22.5]; Glutathione S-transferase, C-terminal domain [PF13410.8, score=21.8]} {Human: ENSG00000163106, HPGDS, hematopoietic prostaglandin D synthase, [Score=78.2, Expect=8e-17]} {Mouse: ENSMUSG00000029919, Hpgds, hematopoietic prostaglandin D synthase, [Score=85.5, Expect=1e-19]} {Celegans: WBGene00001750, gst-2, Glutathione S-transferase 2, [RH, Score=96.7, Expect=3e-24]} {Smed: dd_Smed_v6_1206_0_1, dd_Smed_v6_1206_0_1, [Score=84.3, Expect=2e-19]} {RNA1509_56224} {RNA1310_31890.2} {RNA815_14778}
35. MligTC455_51557 57 1.19 Mlig455_038195

Neo: -

Age: Down-Up-Up

 ISL1 2.473 0.966 - 0.772 - 0.735 - Mlig455_038195 {REF} {Length: 2149} {Pfam: LIM domain [PF00412.24, score=91.4]; Homeodomain [PF00046.31, score=55.3]; Homeobox KN domain [PF05920.13, score=23.4]} {Human: ENSG00000016082, ISL1, ISL LIM homeobox 1, [Score=180, Expect=9e-52]; ENSG00000159556, ISL2, ISL LIM homeobox 2, [Score=173, Expect=3e-49]} {Mouse: ENSMUSG00000042258, Isl1, ISL1 transcription factor, LIM/homeodomain, [Score=180, Expect=6e-52]; ENSMUSG00000032318, Isl2, insulin related protein 2 (islet 2), [Score=175, Expect=4e-50]} {Dmel: FBgn0003896, tup, tailup, [Score=151, Expect=3e-40]} {Celegans: WBGene00002989, lim-7, CeLIM-7; LIM domain family, [Score=142, Expect=2e-37]} {Smed: dd_Smed_v6_8820_0_1, dd_Smed_v6_8820_0_1, [Score=303, Expect=1e-97]} {RNA1310_54855} {RNA815_46288}
36. MligTC455_19775 36 0.74 Mlig455_060359

Neo: -

Age: -

 FCN1 2.45 0.984 - 0.734 - 0.732 - Mlig455_060359 {REF} {Length: 1109} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=120.9]} {Human: ENSG00000085265, FCN1, ficolin 1, [Score=99.0, Expect=2e-23]; ENSG00000142748, FCN3, ficolin 3, [Score=99.0, Expect=1e-23]; ENSG00000160339, FCN2, ficolin 2, [Score=98.2, Expect=2e-23]} {Mouse: ENSMUSG00000026938, Fcna, ficolin A, [Score=100, Expect=3e-24]} {Dmel: FBgn0034160, CG5550, [Score=97.8, Expect=7e-24]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=90.1, Expect=4e-20]} {RNA1310_67383} {RNA815_45536}
37. MligTC455_48522 94 1.96 Mlig455_032491

Neo: -

Age: -

Region-enriched R2: 4.888/0.01251

 1.941 0.994 - - - 0.947 - Mlig455_032491 {REF} {Length: 2169} {Pfam: Sodium / potassium ATPase beta chain [PF00287.20, score=47.3]} {Dmel: FBgn0015776, nrv1, nervana 1, [Score=55.5, Expect=2e-08]} {RNA1310_12303} {RNA815_10417}
38. MligTC455_09472 23 0.47 Mlig455_059329

Neo: -

Age: -

 NGB 1.935 0.984 - - - 0.951 - Mlig455_059329 {REF} {Length: 2110} {Pfam: Globin [PF00042.24, score=52.9]} {Human: ENSG00000165553, NGB, neuroglobin, [RH, Score=48.5, Expect=8e-07]} {Mouse: ENSMUSG00000021032, Ngb, neuroglobin, [RH, Score=50.4, Expect=1e-07]} {RNA1310_93460} {RNA815_18392}
39. MligTC455_53594 55 1.15 Mlig455_028296, Mlig455_069567

Neo: -

Age: Down-Up-Down

 SLC24A2 1.911 0.989 - - - 0.922 -

Mlig455_028296 {REF} {Length: 4685} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=158.5]} {Human: ENSG00000155886, SLC24A2, solute carrier family 24 member 2, [Score=453, Expect=4e-151]} {Mouse: ENSMUSG00000037996, Slc24a2, solute carrier family 24 (sodium/potassium/calcium exchanger), member 2, [Score=453, Expect=9e-151]} {Dmel: FBgn0028704, Nckx30C, [Score=460, Expect=2e-151]} {Celegans: WBGene00003569, ncx-4, Na/Ca eXchangers, [Score=222, Expect=5e-64]} {Smed: dd_Smed_v6_5868_0_4, dd_Smed_v6_5868_0_4, [Score=186, Expect=2e-51]} {RNA1509_26587} {RNA1310_76563} {RNA815_21902.1}

Mlig455_069567 {REF} {Length: 4230} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=186.7]} {Human: ENSG00000155886, SLC24A2, solute carrier family 24 member 2, [RH, Score=496, Expect=1e-167]} {Mouse: ENSMUSG00000037996, Slc24a2, solute carrier family 24 (sodium/potassium/calcium exchanger), member 2, [RH, Score=501, Expect=4e-169]} {Dmel: FBgn0028704, Nckx30C, [RH, Score=501, Expect=3e-167]} {Celegans: WBGene00003569, ncx-4, Na/Ca eXchangers, [Score=226, Expect=4e-65]} {Smed: dd_Smed_v6_5868_0_4, dd_Smed_v6_5868_0_4, [Score=186, Expect=2e-51]} {RNA1509_26587} {RNA1310_76563} {RNA815_21902.1}
40. MligTC455_21502 36 0.75 Mlig455_018529

Neo: -

Age: -

Region-enriched R2: 5.380/0.01311

 1.907 0.974 - - - 0.933 - Mlig455_018529 {REF} {Length: 1004} {Pfam: Fas apoptotic inhibitory molecule (FAIM1) [PF06905.15, score=43.7]} {Mouse: ENSMUSG00000032463, Faim, Fas apoptotic inhibitory molecule, [Score=54.7, Expect=2e-09]} {Smed: dd_Smed_v6_4798_0_1, dd_Smed_v6_4798_0_1, [RH, Score=75.1, Expect=7e-18]} {RNA1310_42034} {RNA815_19884}
41. MligTC455_52656 121 2.51 Mlig455_062381, Mlig455_062408

Neo: -

Age: Down-Up-Down

 1.902 0.990 - - - 0.912 -

Mlig455_062381 {REF} {Length: 2245} {RNA1310_26272} {RNA815_22826}

Mlig455_062408 {REF} {Length: 2277} {RNA1310_26272} {RNA815_37592}
42. MligTC455_34524 155 3.22 Mlig455_021291

Neo: -

Age: Down-Up-Down

Region-specific R2: 4.905

Region-enriched R2: 4.200/0.01842

 1.896 0.997 - - - 0.899 - Mlig455_021291 {REF} {Length: 1478} {NoTransDecoderORF} {RNA1509_56543} {RNA1310_26920, RNA1509_56543} {RNA1509_56543, RNA815_11718}
43. MligTC455_31163 72 1.51 Mlig455_045625

Neo: -

Age: Up-Down-Down

 1.894 0.991 - - - 0.903 - Mlig455_045625 {REF} {Length: 1957} {RNA1509_21720} {RNA1310_14760, RNA1509_21720} {RNA1509_21720, RNA815_24583}
44. MligTC455_17218 37 0.78 Mlig455_053853

Neo: -

Age: -

 1.891 0.981 - 0.910 - - - Mlig455_053853 {REF} {Length: 1743} {RNA1310_61921}
45. MligTC455_13095 40 0.82 Mlig455_036239

Neo: -

Age: -

 1.883 0.970 - 0.913 - - - Mlig455_036239 {REF} {Length: 2786} {RNA1509_41201} {RNA1310_51044} {RNA815_51130}
46. MligTC455_51154 45 0.94 Mlig455_045899

Neo: -

Age: -

 CPED1 1.883 0.977 - 0.906 - - - Mlig455_045899 {REF} {Length: 3530} {Human: ENSG00000106034, CPED1, cadherin like and PC-esterase domain containing 1, [RH, Score=178, Expect=2e-47]} {Mouse: ENSMUSG00000062980, Cped1, cadherin-like and PC-esterase domain containing 1, [RH, Score=179, Expect=6e-48]} {Smed: dd_Smed_v6_14757_0_1, dd_Smed_v6_14757_0_1, [RH, Score=188, Expect=3e-53]} {RNA1509_12903} {RNA1310_19899.1} {RNA815_44464}
47. MligTC455_18309 17 0.35 Mlig455_056133

Neo: -

Age: -

 1.882 0.975 - - - 0.907 - Mlig455_056133 {REF} {Length: 1429} {RNA1310_65004}
48. MligTC455_29408 45 0.94 Mlig455_038322

Neo: -

Age: -

Region-enriched R2: 8.586/0.00762

 MB 1.882 0.996 - - - 0.886 - Mlig455_038322 {REF} {Length: 2059} {Pfam: Globin [PF00042.24, score=57.8]} {Human: ENSG00000198125, MB, myoglobin, [RH, Score=47.8, Expect=5e-07]} {Mouse: ENSMUSG00000018893, Mb, myoglobin, [RH, Score=45.4, Expect=2e-06]} {Celegans: WBGene00008996, glb-14, GLoBin related, [Score=51.6, Expect=4e-08]} {Smed: dd_Smed_v6_15997_0_1, dd_Smed_v6_15997_0_1, [RH, Score=63.5, Expect=1e-12]} {RNA1509_48898} {RNA1310_47695} {RNA815_7096.1}
49. MligTC455_49957 119 2.47 Mlig455_005610, Mlig455_014448

Neo: -

Age: -

 1.881 0.959 - - - 0.922 -

Mlig455_005610 {REF} {Length: 1455} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=66.2, Expect=4e-13]} {RNA1310_45206} {RNA815_28788}

Mlig455_014448 {REF} {Length: 1455} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=63.2, Expect=6e-12]} {RNA1310_45206} {RNA815_28788}
50. MligTC455_40657 90 1.87 Mlig455_040779

Neo: -

Age: -

 CLIP2 1.879 0.960 - - - 0.919 - Mlig455_040779 {REF} {Length: 2164} {Pfam: CAP-Gly domain [PF01302.27, score=60.7]} {Human: ENSG00000106665, CLIP2, CAP-Gly domain containing linker protein 2, [Score=61.6, Expect=2e-09]} {Mouse: ENSMUSG00000063146, Clip2, CAP-GLY domain containing linker protein 2, [Score=62.0, Expect=1e-09]} {Dmel: FBgn0036882, CG9279, [Score=54.7, Expect=1e-07]} {Smed: dd_Smed_v6_12985_0_1, dd_Smed_v6_12985_0_1, [Score=56.2, Expect=2e-08]} {RNA1310_20676} {RNA815_40746}
51. MligTC455_32025 18 0.36 Mlig455_028181, Mlig455_028252

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.602

 1.874 0.988 - - - 0.886 -

Mlig455_028181 {REF} {Length: 4403} {Pfam: PH domain [PF00169.31, score=19.7]} {RNA1310_106355}

Mlig455_028252 {REF} {Length: 3659} {Pfam: PH domain [PF00169.31, score=20.0]} {RNA1310_106355}
52. MligTC455_41541 30 0.62 Mlig455_064895

Neo: -

Age: -

 GLUL 1.873 - - 0.969 - 0.904 - Mlig455_064895 {REF} {Length: 1633} {Pfam: Glutamine synthetase, catalytic domain [PF00120.26, score=57.2]; Glutamine synthetase, beta-Grasp domain [PF03951.21, score=45.1]} {Human: ENSG00000135821, GLUL, glutamate-ammonia ligase, [RH, Score=503, Expect=4e-177]} {Mouse: ENSMUSG00000026473, Glul, glutamate-ammonia ligase (glutamine synthetase), [RH, Score=503, Expect=2e-179]} {Dmel: FBgn0001145, Gs2, Glutamine synthetase 2, [RH, Score=510, Expect=0.0]} {Celegans: WBGene00001604, gln-3, Glutamine synthetase, [RH, Score=511, Expect=0.0]} {Smed: dd_Smed_v6_896_0_1, dd_Smed_v6_896_0_1, [RH, Score=546, Expect=0.0]} {RNA1509_47000} {RNA1310_22329.1, RNA1509_47000} {RNA1509_47000, RNA815_4116.6}
53. MligTC455_14483 140 2.92 Mlig455_028240

Neo: -

Age: -

Region-enriched R2: 6.203/0.04837

 1.867 0.984 - - - 0.883 - Mlig455_028240 {REF} {Length: 728} {RNA1310_111517} {RNA815_9716}
54. MligTC455_45487 110 2.3 Mlig455_004129, Mlig455_060457

Neo: -

Age: -

 1.865 0.984 - - - 0.881 -

Mlig455_004129 {REF} {Length: 1131} {Pfam: PAN domain [PF00024.28, score=18.8]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=64.3, Expect=2e-12]} {RNA1310_37660} {RNA815_17816.1}

Mlig455_060457 {REF} {Length: 1507} {Pfam: PAN domain [PF00024.28, score=19.5]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=64.3, Expect=2e-12]} {RNA1509_54623} {RNA1310_33480} {RNA815_17816.1}
55. MligTC455_35895 102 2.12 Mlig455_063971

Neo: -

Age: -

 RYK 1.863 0.970 - - - 0.893 - Mlig455_063971 {REF} {Length: 3496} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=209.4]; WIF domain [PF02019.20, score=109.7]; Protein kinase domain [PF00069.27, score=79.1]} {Human: ENSG00000163785, RYK, receptor-like tyrosine kinase, [Score=202, Expect=1e-55]} {Mouse: ENSMUSG00000032547, Ryk, receptor-like tyrosine kinase, [RH, Score=202, Expect=2e-55]} {Dmel: FBgn0015380, drl, derailed, [RH, Score=239, Expect=4e-69]} {Celegans: WBGene00003007, lin-18, Inactive tyrosine-protein kinase RYK, [Score=179, Expect=6e-48]} {Smed: dd_Smed_v6_12594_0_2, dd_Smed_v6_12594_0_2, [Score=201, Expect=3e-55]} {RNA1509_58811} {RNA1310_6671.2} {RNA815_41921}
56. MligTC455_46880 44 0.91 Mlig455_046271

Neo: -

Age: -

 IAH1 1.863 0.984 - - - 0.879 - Mlig455_046271 {REF} {Length: 1061} {Pfam: GDSL-like Lipase/Acylhydrolase family [PF13472.8, score=75.8]; GDSL-like Lipase/Acylhydrolase [PF00657.24, score=32.0]} {Human: ENSG00000134330, IAH1, isoamyl acetate hydrolyzing esterase 1 (putative), [Score=138, Expect=2e-39]} {Mouse: ENSMUSG00000062054, Iah1, isoamyl acetate-hydrolyzing esterase 1 homolog, [Score=121, Expect=4e-33]} {Smed: dd_Smed_v6_6241_0_1, dd_Smed_v6_6241_0_1, [Score=111, Expect=8e-30]} {RNA1310_130726}
57. MligTC455_46444 201 4.19 Mlig455_001021

Neo: -

Age: -

 1.861 0.959 - - - 0.902 - Mlig455_001021 {REF} {Length: 629} {RNA1509_14730} {RNA1310_23260} {RNA815_18139}
58. MligTC455_46155 116 2.42 Mlig455_027239

Neo: -

Age: -

Region-enriched R2: 4.163/0.03818

 GRK3 1.859 0.982 - - - 0.877 - Mlig455_027239 {REF} {Length: 2919} {Pfam: Protein kinase domain [PF00069.27, score=226.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=100.5]; Regulator of G protein signaling domain [PF00615.21, score=48.3]} {Human: ENSG00000100077, GRK3, G protein-coupled receptor kinase 3, [Score=845, Expect=0.0]; ENSG00000173020, GRK2, G protein-coupled receptor kinase 2, [Score=838, Expect=0.0]} {Mouse: ENSMUSG00000042249, Grk3, G protein-coupled receptor kinase 3, [Score=838, Expect=0.0]; ENSMUSG00000024858, Grk2, G protein-coupled receptor kinase 2, [Score=838, Expect=0.0]} {Dmel: FBgn0260798, Gprk1, G protein-coupled receptor kinase 1, [Score=842, Expect=0.0]} {Celegans: WBGene00001709, grk-2, G protein-coupled receptor kinase 2, [Score=819, Expect=0.0]} {Smed: dd_Smed_v6_6480_0_1, dd_Smed_v6_6480_0_1, [Score=949, Expect=0.0]} {RNA1509_7002} {RNA1310_16658} {RNA815_28070}
59. MligTC455_14059 24 0.5 Mlig455_037086

Neo: -

Age: -

Region-enriched R2: 8.935/0.00338

 1.857 0.984 - - - 0.873 - Mlig455_037086 {REF} {Length: 1622} {Pfam: Galactosyltransferase [PF01762.23, score=18.6]} {RNA1310_57689} {RNA815_57743}
60. MligTC455_09456 47 0.97 Mlig455_029993

Neo: -

Age: -

Region-enriched R2: 5.041/0.00960

 1.851 0.988 - - - 0.863 - Mlig455_029993 {REF} {Length: 3167} {RNA1509_44134} {RNA1310_31411} {RNA815_45870}
61. MligTC455_19709 221 4.6 Mlig455_010385

Neo: -

Age: -

Region-enriched R2: 4.689/0.03280

 1.851 0.984 - - - 0.867 - Mlig455_010385 {REF} {Length: 903} {Pfam: Pancreatic hormone peptide [PF00159.20, score=43.2]} {RNA1509_54211} {RNA1310_54505.2} {RNA815_29389}
62. MligTC455_37047 45 0.94 Mlig455_046180

Neo: -

Age: -

 1.851 0.959 - - - 0.892 - Mlig455_046180 {REF} {Length: 1686} {RNA1310_140241} {RNA815_12716}
63. MligTC455_42484 246 5.12 Mlig455_046416

Neo: -

Age: Down-Up-Down

Region-specific R2: 4.313

Region-enriched R2: 2.983/0.00930

 1.851 0.981 - - - 0.870 - Mlig455_046416 {REF} {Length: 1006} {RNA1310_40237.1} {RNA815_18246}
64. MligTC455_40040 365 7.61 Mlig455_008332

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.784

Region-specific R2: 6.834

Region-enriched R2: 5.705/0.00005

 1.849 0.992 - - - 0.857 - Mlig455_008332 {REF} {Length: 707} {RNA1509_39735} {RNA1310_73916, RNA1509_39735} {RNA1509_39735, RNA815_42730.2}
65. MligTC455_10299 72 1.51 Mlig455_023028, Mlig455_023125, Mlig455_023183

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.617

Region-enriched R2: 4.572/0.04281

 ANGPTL1 1.847 0.992 - 0.855 - - -

Mlig455_023028 {REF} {Length: 2538} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=130.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=115, Expect=8e-29]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=112, Expect=1e-27]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=114, Expect=2e-28]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=112, Expect=9e-28]} {Dmel: FBgn0050280, CG30280, [Score=103, Expect=9e-26]} {Smed: dd_Smed_v6_74244_0_1, dd_Smed_v6_74244_0_1, [Score=50.8, Expect=4e-08]} {RNA1509_41017} {RNA1310_41391} {RNA815_23568}

Mlig455_023125 {REF} {Length: 2398} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=127.5]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=112, Expect=2e-27]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=107, Expect=1e-25]} {Mouse: ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=107, Expect=7e-26]} {Dmel: FBgn0050280, CG30280, [Score=92.8, Expect=6e-22]} {Smed: dd_Smed_v6_74244_0_1, dd_Smed_v6_74244_0_1, [Score=51.2, Expect=3e-08]} {RNA1509_41017} {RNA1310_41391} {RNA815_23568}

Mlig455_023183 {REF} {Length: 2190} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=129.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=115, Expect=2e-28]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=110, Expect=9e-27]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=113, Expect=4e-28]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=110, Expect=6e-27]} {Dmel: FBgn0003326, sca, scabrous, [Score=104, Expect=8e-25]} {Smed: dd_Smed_v6_74244_0_1, dd_Smed_v6_74244_0_1, [Score=50.4, Expect=4e-08]} {RNA1509_41017} {RNA1310_41391} {RNA815_23568}
66. MligTC455_25701 31 0.65 Mlig455_017477

Neo: -

Age: -

 1.834 0.984 - - - 0.850 - Mlig455_017477 {REF} {Length: 664} {RNA1310_52753} {RNA815_26527}
67. MligTC455_18300 66 1.39 Mlig455_023416, Mlig455_023444

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.480

Region-enriched R2: 5.316/0.00583

 1.831 - - 0.974 - 0.857 -

Mlig455_023416 {REF} {Length: 1159} {RNA1310_76698} {RNA815_41333}

Mlig455_023444 {REF} {Length: 1183} {RNA1310_76698} {RNA815_41333}
68. MligTC455_36686 47 0.97 Mlig455_056861

Neo: -

Age: -

 1.831 - - 0.957 - 0.874 - Mlig455_056861 {REF} {Length: 6184} {RNA1509_14690} {RNA1310_36097} {RNA815_32539}
69. MligTC455_26356 62 1.3 Mlig455_042551

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.548

 GRIK2 1.83 0.983 - - - 0.847 - Mlig455_042551 {REF} {Length: 2917} {Pfam: Ligand-gated ion channel [PF00060.28, score=82.2]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=60.7]; Receptor family ligand binding region [PF01094.30, score=32.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=27.3]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=144, Expect=9e-35]; ENSG00000152208, GRID2, glutamate ionotropic receptor delta type subunit 2, [Score=141, Expect=7e-34]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=143, Expect=1e-34]; ENSMUSG00000071424, Grid2, glutamate receptor, ionotropic, delta 2, [Score=142, Expect=2e-34]} {Dmel: FBgn0051201, GluRIIE, Glutamate receptor IIE, [Score=119, Expect=3e-27]} {Celegans: WBGene00001616, glr-5, GLutamate Receptor family (AMPA), [Score=123, Expect=2e-28]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=247, Expect=4e-74]} {RNA1310_21865} {RNA815_26044}
70. MligTC455_52458 63 1.3 Mlig455_059320

Neo: -

Age: -

 1.828 0.873 - 0.955 - - - Mlig455_059320 {REF} {Length: 1622} {Pfam: Universal stress protein family [PF00582.28, score=92.6]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=97.4, Expect=1e-26]} {RNA1509_15153} {RNA1310_55094} {RNA815_23718.1}
71. MligTC455_12574 95 1.98 Mlig455_010864, Mlig455_010895

Neo: -

Age: -

 1.826 0.977 - 0.849 - - -

Mlig455_010864 {REF} {Length: 886} {RNA1310_70414} {RNA815_36183}

Mlig455_010895 {REF} {Length: 627} {RNA1310_70414} {RNA815_36183}
72. MligTC455_40502 75 1.57 Mlig455_011578

Neo: -

Age: Down-Up-Down

 SPATA18 1.822 - - 0.846 - 0.976 - Mlig455_011578 {REF} {Length: 2873} {TRANSSPLICED} {Pfam: Mitochondria-eating protein [PF16026.7, score=153.7]} {Human: ENSG00000163071, SPATA18, spermatogenesis associated 18, [Score=179, Expect=2e-48]} {Mouse: ENSMUSG00000029155, Spata18, spermatogenesis associated 18, [Score=220, Expect=3e-63]} {Smed: dd_Smed_v6_6321_0_1, dd_Smed_v6_6321_0_1, [Score=344, Expect=3e-111]} {RNA1509_30652} {RNA1310_30604} {RNA815_17332}
73. MligTC455_19329 90 1.88 Mlig455_068578

Neo: -

Age: -

Region-enriched R2: 3.988/0.02701

 CHAT 1.813 0.987 - - - 0.826 - Mlig455_068578 {REF} {Length: 3661} {TRANSSPLICED} {Pfam: Choline/Carnitine o-acyltransferase [PF00755.22, score=556.7]} {Human: ENSG00000070748, CHAT, choline O-acetyltransferase, [RH, Score=519, Expect=2e-177]} {Mouse: ENSMUSG00000021919, Chat, choline acetyltransferase, [RH, Score=520, Expect=7e-178]} {Dmel: FBgn0000303, ChAT, Choline acetyltransferase, [RH, Score=488, Expect=1e-164]} {Celegans: WBGene00000481, cha-1, Choline O-acetyltransferase, [RH, Score=363, Expect=2e-117]} {Smed: dd_Smed_v6_6208_0_1, dd_Smed_v6_6208_0_1, [RH, Score=601, Expect=0.0]} {RNA1509_36058} {RNA1310_3092, RNA1509_36058} {RNA1509_36058, RNA815_2435.1}
74. MligTC455_53595 20 0.42 Mlig455_067432

Neo: -

Age: -

 SLC24A2 1.813 0.983 - 0.830 - - - Mlig455_067432 {REF} {Length: 4224} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=186.7]} {Human: ENSG00000155886, SLC24A2, solute carrier family 24 member 2, [RH, Score=498, Expect=4e-168]} {Mouse: ENSMUSG00000037996, Slc24a2, solute carrier family 24 (sodium/potassium/calcium exchanger), member 2, [RH, Score=502, Expect=2e-169]} {Dmel: FBgn0028704, Nckx30C, [RH, Score=499, Expect=2e-166]} {Celegans: WBGene00003569, ncx-4, Na/Ca eXchangers, [Score=223, Expect=3e-64]} {Smed: dd_Smed_v6_5868_0_4, dd_Smed_v6_5868_0_4, [Score=184, Expect=9e-51]} {RNA1509_26587} {RNA1310_76563} {RNA815_21902.1}
75. MligTC455_15859 120 2.49 Mlig455_007414, Mlig455_067681

Neo: -

Age: -

 1.807 0.984 - - - 0.823 -

Mlig455_007414 {REF} {Length: 914} {RNA1310_61579} {RNA815_24378}

Mlig455_067681 {REF} {Length: 917} {RNA1310_61579} {RNA815_24378}
76. MligTC455_39860 56 1.17 Mlig455_046932

Neo: -

Age: -

 1.802 0.959 - - - 0.843 - Mlig455_046932 {REF} {Length: 920} {RNA1310_30968} {RNA815_45889}
77. MligTC455_27313 61 1.27 Mlig455_031814, Mlig455_047613

Neo: -

Age: -

 WSCD2 1.801 0.984 - 0.817 - - -

Mlig455_031814 {REF} {Length: 844} {Pfam: WSC domain [PF01822.21, score=66.1]; PAN domain [PF00024.28, score=19.7]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=62.0, Expect=7e-11]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=60.5, Expect=1e-10]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=56.6, Expect=3e-09]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=48.5, Expect=1e-06]} {RNA1509_43359} {RNA1310_33892} {RNA815_23776.1}

Mlig455_047613 {REF} {Length: 843} {Pfam: WSC domain [PF01822.21, score=52.5]; PAN domain [PF00024.28, score=19.2]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=52.0, Expect=5e-08]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=48.9, Expect=4e-07]} {RNA1509_43359} {RNA1310_33892} {RNA815_23776.1}
78. MligTC455_24568 25 0.51 Mlig455_038127

Neo: -

Age: Down-Up-Down

 CACNA2D2 1.8 0.960 - - - 0.840 - Mlig455_038127 {REF} {Length: 4202} {Pfam: von Willebrand factor type A domain [PF13519.8, score=41.5]; von Willebrand factor type A domain [PF00092.30, score=36.2]; von Willebrand factor type A domain [PF13768.8, score=30.8]} {Human: ENSG00000007402, CACNA2D2, calcium voltage-gated channel auxiliary subunit alpha2delta 2, [Score=82.8, Expect=2e-16]; ENSG00000157445, CACNA2D3, calcium voltage-gated channel auxiliary subunit alpha2delta 3, [Score=79.3, Expect=3e-15]; ENSG00000153956, CACNA2D1, calcium voltage-gated channel auxiliary subunit alpha2delta 1, [Score=79.0, Expect=4e-15]} {Mouse: ENSMUSG00000010066, Cacna2d2, calcium channel, voltage-dependent, alpha 2/delta subunit 2, [Score=82.4, Expect=2e-16]; ENSMUSG00000040118, Cacna2d1, calcium channel, voltage-dependent, alpha2/delta subunit 1, [Score=79.3, Expect=3e-15]} {Celegans: WBGene00007041, tag-180, [Score=62.0, Expect=4e-10]} {Smed: dd_Smed_v6_19048_0_1, dd_Smed_v6_19048_0_1, [Score=430, Expect=2e-140]} {RNA1509_28096} {RNA1310_2030} {RNA815_1872}
79. MligTC455_29914 44 0.91 Mlig455_027923

Neo: -

Age: Down-Up-Down

Region-enriched R2: 8.096/0.00455

 ANGPTL3 1.79 0.979 - - - 0.811 - Mlig455_027923 {REF} {Length: 1663} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=70.5]} {Human: ENSG00000132855, ANGPTL3, angiopoietin like 3, [Score=60.5, Expect=9e-10]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=59.3, Expect=2e-09]; ENSG00000120332, TNN, tenascin N, [Score=58.9, Expect=3e-09]} {Mouse: ENSMUSG00000015829, Tnr, tenascin R, [Score=62.4, Expect=2e-10]} {Dmel: FBgn0031804, CG9500, [Score=76.3, Expect=6e-16]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=51.2, Expect=3e-07]} {RNA1509_53291} {RNA1310_58974} {RNA815_43288.3}
80. MligTC455_29929 164 3.41 Mlig455_030237, Mlig455_068015

Neo: -

Age: -

Region-enriched R2: 4.901/0.00350

 SIX6 1.79 0.977 - - - 0.813 -

Mlig455_030237 {REF} {Length: 2545} {Pfam: Transcriptional regulator, SIX1, N-terminal SD domain [PF16878.7, score=152.1]; Homeodomain [PF00046.31, score=46.4]; Homeobox KN domain [PF05920.13, score=40.1]} {Human: ENSG00000184302, SIX6, SIX homeobox 6, [RH, Score=327, Expect=1e-109]; ENSG00000138083, SIX3, SIX homeobox 3, [RH, Score=325, Expect=8e-108]} {Mouse: ENSMUSG00000038805, Six3, sine oculis-related homeobox 3, [RH, Score=325, Expect=6e-108]; ENSMUSG00000021099, Six6, sine oculis-related homeobox 6, [RH, Score=323, Expect=2e-108]} {Dmel: FBgn0025360, Optix, [RH, Score=291, Expect=9e-93]} {Celegans: WBGene00000453, ceh-32, Homeobox protein ceh-32, [RH, Score=237, Expect=2e-72]} {Smed: dd_Smed_v6_11975_0_1, dd_Smed_v6_11975_0_1, [RH, Score=360, Expect=2e-119]} {RNA1509_39396} {RNA1310_25182.2} {RNA815_23127}

Mlig455_068015 {REF} {Length: 2713} {Pfam: Transcriptional regulator, SIX1, N-terminal SD domain [PF16878.7, score=152.2]; Homeodomain [PF00046.31, score=46.4]; Homeobox KN domain [PF05920.13, score=40.1]} {Human: ENSG00000184302, SIX6, SIX homeobox 6, [RH, Score=327, Expect=1e-109]; ENSG00000138083, SIX3, SIX homeobox 3, [RH, Score=325, Expect=7e-108]} {Mouse: ENSMUSG00000038805, Six3, sine oculis-related homeobox 3, [RH, Score=325, Expect=5e-108]; ENSMUSG00000021099, Six6, sine oculis-related homeobox 6, [RH, Score=323, Expect=2e-108]} {Dmel: FBgn0025360, Optix, [RH, Score=291, Expect=1e-92]} {Celegans: WBGene00000453, ceh-32, Homeobox protein ceh-32, [RH, Score=237, Expect=1e-72]} {Smed: dd_Smed_v6_11975_0_1, dd_Smed_v6_11975_0_1, [RH, Score=360, Expect=1e-119]} {RNA1509_39396} {RNA1310_25182.2} {RNA815_23127}
81. MligTC455_18333 273 5.7 Mlig455_010935

Neo: -

Age: Down-Up-Up

Region-enriched R2: 5.059/0.00307

 1.789 0.975 - - - 0.814 - Mlig455_010935 {REF} {Length: 510} {RNA1310_33328.2} {RNA815_15093.1}
82. MligTC455_42650 33 0.69 Mlig455_027379

Neo: -

Age: -

 1.784 0.950 - - - 0.834 - Mlig455_027379 {REF} {Length: 661} {RNA1310_47424} {RNA815_44231}
83. MligTC455_33854 41 0.85 Mlig455_031601

Neo: -

Age: -

Region-enriched R2: 5.730/0.00808

 1.783 0.968 - - - 0.815 - Mlig455_031601 {REF} {Length: 1072} {RNA1310_42312} {RNA815_56269}
84. MligTC455_33040 203 4.23 Mlig455_032497

Neo: -

Age: logFC(26M/2M)=0.515

Region-enriched R2: 4.005/0.00408

 PKD2L1 1.776 0.960 - - - 0.816 - Mlig455_032497 {REF} {Length: 3318} {Pfam: Polycystin cation channel [PF08016.14, score=293.1]; Ion transport protein [PF00520.33, score=39.7]} {Human: ENSG00000107593, PKD2L1, polycystin 2 like 1, transient receptor potential cation channel, [Score=236, Expect=4e-66]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=261, Expect=3e-73]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=131, Expect=5e-31]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=180, Expect=1e-47]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [Score=641, Expect=0.0]} {RNA1509_3444} {RNA1310_89} {RNA815_1814}
85. MligTC455_16875 42 0.88 Mlig455_028243

Neo: -

Age: Up-Down-Down

 KCNK16 1.772 0.981 - 0.791 - - - Mlig455_028243 {REF} {Length: 2676} {Pfam: Ion channel [PF07885.18, score=116.8]; Ion transport protein [PF00520.33, score=28.8]; Protein of unknown function (DUF3112) [PF11309.10, score=19.5]} {Human: ENSG00000095981, KCNK16, potassium two pore domain channel subfamily K member 16, [Score=97.8, Expect=5e-22]; ENSG00000186795, KCNK18, potassium two pore domain channel subfamily K member 18, [Score=97.4, Expect=2e-21]; ENSG00000100433, KCNK10, potassium two pore domain channel subfamily K member 10, [Score=94.4, Expect=6e-20]} {Mouse: ENSMUSG00000040901, Kcnk18, potassium channel, subfamily K, member 18, [Score=102, Expect=4e-23]; ENSMUSG00000023387, Kcnk16, potassium channel, subfamily K, member 16, [Score=98.2, Expect=2e-22]} {Dmel: FBgn0033257, sand, sandman, [Score=150, Expect=2e-40]} {Celegans: WBGene00010784, twk-48, TWiK family of potassium channels, [Score=162, Expect=5e-45]} {Smed: dd_Smed_v6_17586_0_1, dd_Smed_v6_17586_0_1, [Score=340, Expect=2e-113]} {RNA1509_39975} {RNA1310_18301.1, RNA1509_39975} {RNA1509_39975, RNA815_12440}
86. MligTC455_44966 574 11.95 Mlig455_036578, Mlig455_057773

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.756

Region-specific R2: 7.016

Region-enriched R2: 7.690/0.00000

 1.771 0.987 - - - 0.784 -

Mlig455_036578 {REF} {Length: 1101} {RNA1509_34765} {RNA1310_57079} {RNA815_29388}

Mlig455_057773 {REF} {Length: 629} {RNA1509_34765} {RNA1310_57079, RNA1509_34765} {RNA1509_34765, RNA815_29388}
87. MligTC455_48692 15 0.32 Mlig455_021398

Neo: -

Age: -

Region-enriched R2: 8.096/0.02429

 1.768 0.996 - - - 0.772 - Mlig455_021398 {REF} {Length: 1571} {Pfam: Ankyrin repeat [PF00023.32, score=20.9]; Ankyrin repeats (many copies) [PF13637.8, score=20.4]; Ankyrin repeats (many copies) [PF13857.8, score=19.6]; Ankyrin repeats (3 copies) [PF12796.9, score=19.4]} {Smed: dd_Smed_v6_29956_0_1, dd_Smed_v6_29956_0_1, [Score=54.7, Expect=3e-08]} {RNA1310_69005}
88. MligTC455_04786 26 0.55 Mlig455_043817, Mlig455_047431

Neo: -

Age: -

 1.766 0.984 - 0.782 - - -

Mlig455_043817 {REF} {Length: 319} {NoTransDecoderORF} {RNA1310_64690}

Mlig455_047431 {REF} {Length: 2194} {Pfam: Glycine rich protein [PF12810.9, score=25.3]} {RNA1509_16377} {RNA1310_33363.2} {RNA815_25152}
89. MligTC455_37200 32 0.67 Mlig455_030215, Mlig455_030221, Mlig455_067995, Mlig455_067998

Neo: -

Age: -

 1.766 0.984 - 0.782 - - -

Mlig455_030215 {REF} {Length: 1088} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=23.5]} {Smed: dd_Smed_v6_26560_0_2, dd_Smed_v6_26560_0_2, [Score=106, Expect=1e-25]} {RNA1310_102374}

Mlig455_030221 {REF} {Length: 1980} {RNA1310_56149} {RNA815_31265}

Mlig455_067995 {REF} {Length: 792} {Pfam: SAP domain [PF02037.29, score=35.7]} {RNA1509_8096} {RNA1310_1771} {RNA815_801}

Mlig455_067998 {REF} {Length: 1295} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=24.0]} {Smed: dd_Smed_v6_26560_0_2, dd_Smed_v6_26560_0_2, [Score=105, Expect=2e-25]} {RNA1310_102374}
90. MligTC455_21966 27 0.56 Mlig455_005716

Neo: -

Age: -

 1.764 0.966 - - - 0.798 - Mlig455_005716 {REF} {Length: 4013} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=186.5]} {Mouse: ENSMUSG00000030873, Scnn1b, sodium channel, nonvoltage-gated 1 beta, [Score=52.4, Expect=1e-06]} {Smed: dd_Smed_v6_23771_0_1, dd_Smed_v6_23771_0_1, [RH, Score=382, Expect=2e-124]} {RNA1509_57431} {RNA1310_11500} {RNA815_5893}
91. MligTC455_44713 661 13.77 Mlig455_048154

Neo: -

Age: logFC(26M/2M)=0.569

Region-specific R2: 3.883

Region-enriched R2: 3.422/0.00000

 1.761 0.964 - - - 0.797 - Mlig455_048154 {REF} {Length: 1173} {RNA1509_34252} {RNA1310_54269.1} {RNA815_55074}
92. MligTC455_44186 185 3.85 Mlig455_052492

Neo: -

Age: -

 1.759 0.984 - - - 0.775 - Mlig455_052492 {REF} {Length: 959} {Pfam: Lectin C-type domain [PF00059.23, score=33.2]} {RNA1509_20946} {RNA1310_41618} {RNA815_32434}
93. MligTC455_19041 54 1.12 Mlig455_030662

Neo: -

Age: -

Region-enriched R2: 9.337/0.00002
Region-enriched R3: 6.044/0.00168

 CAV1 1.758 0.974 - - - 0.784 - Mlig455_030662 {REF} {Length: 940} {Pfam: Caveolin [PF01146.19, score=117.8]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=98.2, Expect=1e-26]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=99.4, Expect=3e-27]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [Score=73.9, Expect=6e-17]} {Smed: dd_Smed_v6_6535_0_1, dd_Smed_v6_6535_0_1, [RH, Score=133, Expect=6e-41]} {RNA1509_53325} {RNA1310_97043} {RNA815_32565}
94. MligTC455_17363 62 1.28 Mlig455_003936

Neo: -

Age: -

 1.757 0.984 - - - 0.773 - Mlig455_003936 {REF} {Length: 1252} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=45.9]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=26.4]} {RNA1310_47889} {RNA815_24646}
95. MligTC455_34499 65 1.36 Mlig455_025160, Mlig455_063937

Neo: -

Age: -

 1.757 0.976 - 0.781 - - -

Mlig455_025160 {REF} {Length: 942} {RNA1310_54940} {RNA815_33690.1}

Mlig455_063937 {REF} {Length: 995} {RNA1310_54940} {RNA815_33690.1}
96. MligTC455_11558 137 2.85 Mlig455_058259

Neo: -

Age: logFC(26M/2M)=-0.792

 1.755 0.968 - - - 0.787 - Mlig455_058259 {REF} {Length: 896} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=19.9]} {RNA1509_58923} {RNA1310_41706, RNA1509_58923} {RNA1509_58923, RNA815_20876}
97. MligTC455_48604 173 3.6 Mlig455_031074

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.490

 1.751 0.981 - - - 0.770 - Mlig455_031074 {REF} {Length: 652} {RNA1310_66509}
98. MligTC455_23600 9 0.19 Mlig455_039858

Neo: -

Age: -

 NKX2-4 1.75 0.976 - 0.774 - - - Mlig455_039858 {REF} {Length: 4395} {Pfam: Homeodomain [PF00046.31, score=70.7]} {Human: ENSG00000125816, NKX2-4, NK2 homeobox 4, [Score=126, Expect=2e-32]; ENSG00000136352, NKX2-1, NK2 homeobox 1, [Score=125, Expect=5e-32]} {Mouse: ENSMUSG00000054160, Nkx2-4, NK2 homeobox 4, [Score=127, Expect=6e-33]; ENSMUSG00000001496, Nkx2-1, NK2 homeobox 1, [Score=125, Expect=5e-32]} {Dmel: FBgn0028993, scro, scarecrow, [Score=159, Expect=6e-44]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [Score=124, Expect=2e-32]} {Smed: dd_Smed_v6_6729_0_1, dd_Smed_v6_6729_0_1, [Score=172, Expect=5e-50]} {RNA1310_77830} {RNA815_63657}
99. MligTC455_10226 119 2.48 Mlig455_023508, Mlig455_023518, Mlig455_023617

Neo: -

Age: -

 1.749 0.994 - - - 0.755 -

Mlig455_023508 {REF} {Length: 1311} {RNA1310_22533.2} {RNA815_23050}

Mlig455_023518 {REF} {Length: 1413} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=21.5]} {RNA1310_22533.2} {RNA815_23050}

Mlig455_023617 {REF} {Length: 1414} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=19.6]} {RNA1310_22533.2} {RNA815_23050}
100. MligTC455_10228 50 1.05 Mlig455_023553

Neo: -

Age: -

 1.749 0.991 - - - 0.758 - Mlig455_023553 {REF} {Length: 1195} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=20.0]} {RNA1310_22533.1} {RNA815_23050}

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