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Results for MligTC455_39935

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_39935 46 0.95 Mlig455_068175

Neo: -

Age: Up-Down-Down

 NPNT Mlig455_068175 {REF} {Length: 5966} {Pfam: Calcium-binding EGF domain [PF07645.17, score=32.4]; EGF domain [PF12947.9, score=32.4]; TNFR/NGFR cysteine-rich region [PF00020.20, score=31.2]} {Human: ENSG00000168743, NPNT, nephronectin, [Score=55.8, Expect=5e-07]; ENSG00000123146, ADGRE5, adhesion G protein-coupled receptor E5, [Score=55.1, Expect=1e-06]; ENSG00000143341, HMCN1, hemicentin 1, [Score=54.3, Expect=4e-07]} {Mouse: ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=55.5, Expect=8e-07]} {Celegans: WBGene00022816, fbn-1, FBN-1A.1; FiBrilliN homolog, [Score=55.1, Expect=4e-07]} {Smed: dd_Smed_v6_41535_0_1, dd_Smed_v6_41535_0_1, [Score=119, Expect=3e-27]} {RNA1310_14177} {RNA815_31673}

Cumulative graph for MligTC455_39935

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.275 1.38 0.99971 1.00000
RegionR2 1.467 1.38 0.28981 0.67839
RegionR3 -1.111 1.38 0.99969 1.00000
RegionR4 0.713 1.38 0.37052 0.69374
RegionR5 -1.046 1.38 0.99968 1.00000
RegionR6 1.819 1.38 0.14982 0.68991
RegionR7 -1.163 1.38 0.99971 1.00000
RegionR8 -0.405 1.38 0.99970 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.518 1.38 0.99995 1.00000
RegenerationR2 2.903 1.38 0.02027 0.23401
RegenerationR3 3.717 1.38 0.05527 0.40419
RegenerationR4 0.973 1.38 0.55400 0.89390
RegenerationR5 3.75 1.38 0.01767 0.23145
RegenerationR6 -0.959 1.38 0.51105 0.81406
RegenerationBL -2.157 1.38 0.99977 1.00000
RegenerationTP 4.272 1.38 0.11650 0.52212


Genes with expression patterns similar to MligTC455_39935

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_39935 46 0.95 Mlig455_068175

Neo: -

Age: Up-Down-Down

 NPNT 4 - - 1.000 1.000 1.000 1.000 Mlig455_068175 {REF} {Length: 5966} {Pfam: Calcium-binding EGF domain [PF07645.17, score=32.4]; EGF domain [PF12947.9, score=32.4]; TNFR/NGFR cysteine-rich region [PF00020.20, score=31.2]} {Human: ENSG00000168743, NPNT, nephronectin, [Score=55.8, Expect=5e-07]; ENSG00000123146, ADGRE5, adhesion G protein-coupled receptor E5, [Score=55.1, Expect=1e-06]; ENSG00000143341, HMCN1, hemicentin 1, [Score=54.3, Expect=4e-07]} {Mouse: ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=55.5, Expect=8e-07]} {Celegans: WBGene00022816, fbn-1, FBN-1A.1; FiBrilliN homolog, [Score=55.1, Expect=4e-07]} {Smed: dd_Smed_v6_41535_0_1, dd_Smed_v6_41535_0_1, [Score=119, Expect=3e-27]} {RNA1310_14177} {RNA815_31673}
2. MligTC455_27070 41 0.86 Mlig455_041645

Neo: -

Age: -

 2.564 - - 0.827 - 0.783 0.954 Mlig455_041645 {REF} {Length: 485} {NoTransDecoderORF} {RNA1509_59553} {RNA1310_99471} {RNA815_64986}
3. MligTC455_00094 97 2.03 Mlig455_053071

Neo: -

Age: -

 2.526 - - 0.962 - 0.807 0.757 Mlig455_053071 {REF} {Length: 358} {RNA1509_59833} {RNA1310_74589, RNA1509_59833}
4. MligTC455_35426 27 0.55 Mlig455_043708, Mlig455_043796, Mlig455_047447

Neo: -

Age: -

Region-enriched R4: 3.107/0.04694

 COG2, TRAF3, TRAF6 2.413 - - 0.958 - 0.743 0.712

Mlig455_043708 {REF} {Length: 2314} {Pfam: TRAF-type zinc finger [PF02176.20, score=41.5]; Seven in absentia protein family [PF03145.18, score=23.6]} {Human: ENSG00000131323, TRAF3, TNF receptor associated factor 3, [Score=161, Expect=1e-41]} {Mouse: ENSMUSG00000021277, Traf3, TNF receptor-associated factor 3, [Score=158, Expect=6e-41]} {Dmel: FBgn0026319, Traf4, TNF-receptor-associated factor 4, [Score=83.6, Expect=1e-16]} {Celegans: WBGene00006612, trf-1, TNF Receptor Associated Factor (TRAF) homolog; TRF-1, [Score=69.3, Expect=4e-12]} {Smed: dd_Smed_v6_168_0_1, dd_Smed_v6_168_0_1, [Score=103, Expect=2e-23]} {RNA1509_50896} {RNA1310_6468} {RNA815_1472}

Mlig455_043796 {REF} {Length: 4177} {TRANSSPLICED} {Pfam: COG (conserved oligomeric Golgi) complex component, COG2 [PF06148.13, score=104.6]; Domain of unknown function (DUF3510) [PF12022.10, score=94.3]; TRAF-type zinc finger [PF02176.20, score=30.8]} {Human: ENSG00000135775, COG2, component of oligomeric golgi complex 2, [Score=280, Expect=6e-80]} {Mouse: ENSMUSG00000031979, Cog2, component of oligomeric golgi complex 2, [Score=274, Expect=5e-78]} {Dmel: FBgn0026634, ldlCp, ldlCp-related protein, [Score=196, Expect=5e-52]} {Celegans: WBGene00000585, cogc-2, Conserved oligomeric Golgi complex subunit 2, [Score=132, Expect=3e-31]} {Smed: dd_Smed_v6_5210_0_1, dd_Smed_v6_5210_0_1, [Score=276, Expect=9e-79]} {RNA1509_17078} {RNA1310_5891} {RNA815_1472}

Mlig455_047447 {REF} {Length: 1314} {TRANSSPLICED} {Pfam: TRAF-type zinc finger [PF02176.20, score=34.2]; Seven in absentia protein family [PF03145.18, score=19.2]} {Human: ENSG00000175104, TRAF6, TNF receptor associated factor 6, [Score=96.7, Expect=4e-21]} {Mouse: ENSMUSG00000027164, Traf6, TNF receptor-associated factor 6, [Score=90.9, Expect=2e-19]} {Smed: dd_Smed_v6_168_0_1, dd_Smed_v6_168_0_1, [Score=100, Expect=4e-23]} {RNA1509_12449} {RNA1310_8751} {RNA815_1472}
5. MligTC455_26268 55 1.15 Mlig455_048366

Neo: -

Age: -

 CDR1 1.89 - - - - 0.973 0.917 Mlig455_048366 {REF} {Length: 1818} {Pfam: Bacterial transferase hexapeptide (six repeats) [PF00132.26, score=47.8]} {Human: ENSG00000184258, CDR1, cerebellar degeneration related protein 1, [RH, Score=54.3, Expect=2e-08]} {RNA1509_12420} {RNA1310_46323} {RNA815_13104.1}
6. MligTC455_27865 53 1.11 Mlig455_035921

Neo: -

Age: -

Regeneration-upregulated R2: 5.914

Regeneration-enriched R2: 5.914

 SPRR3 1.868 - - - - 0.953 0.915 Mlig455_035921 {REF} {Length: 1730} {Pfam: Cornifin (SPRR) family [PF02389.17, score=56.6]; Fibrinogen binding protein [PF08017.13, score=18.2]} {Human: ENSG00000163209, SPRR3, small proline rich protein 3, [RH, Score=71.2, Expect=2e-14]} {RNA1509_35339} {RNA1310_43126.1}
7. MligTC455_38701 102 2.13 Mlig455_015653, Mlig455_023761

Neo: -

Age: -

 ANK1, FPGT-TNNI3K 1.792 - - - - 0.840 0.952

Mlig455_015653 {REF} {Length: 5454} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=72.8]; Ankyrin repeats (many copies) [PF13857.8, score=71.0]; Ankyrin repeats (many copies) [PF13637.8, score=55.5]; Ankyrin repeat [PF00023.32, score=54.3]; Ankyrin repeat [PF13606.8, score=41.5]} {Human: ENSG00000029534, ANK1, ankyrin 1, [Score=72.0, Expect=2e-15]; ENSG00000154065, ANKRD29, ankyrin repeat domain 29, [Score=70.1, Expect=3e-15]; ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=68.6, Expect=3e-14]} {Mouse: ENSMUSG00000031543, Ank1, ankyrin 1, erythroid, [Score=74.7, Expect=1e-16]} {Dmel: FBgn0261554, CG42672, [Score=63.9, Expect=5e-13]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=67.8, Expect=2e-14]} {Smed: dd_Smed_v6_9936_0_1, dd_Smed_v6_9936_0_1, [Score=77.8, Expect=5e-18]} {RNA1509_28959} {RNA1310_10537} {RNA815_15195}

Mlig455_023761 {REF} {Length: 3109} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=70.7]; Ankyrin repeat [PF00023.32, score=65.6]; Ankyrin repeats (many copies) [PF13637.8, score=57.1]; Ankyrin repeat [PF13606.8, score=46.0]; Ankyrin repeats (many copies) [PF13857.8, score=45.3]; Mab-21 protein [PF03281.16, score=25.8]} {Human: ENSG00000259030, FPGT-TNNI3K, FPGT-TNNI3K readthrough, [Score=77.8, Expect=2e-14]; ENSG00000116783, TNNI3K, TNNI3 interacting kinase, [Score=77.4, Expect=3e-14]; ENSG00000029534, ANK1, ankyrin 1, [Score=75.9, Expect=1e-13]; ENSG00000151150, ANK3, ankyrin 3, [Score=75.1, Expect=2e-13]; ENSG00000085382, HACE1, HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1, [Score=74.7, Expect=2e-13]} {Mouse: ENSMUSG00000040086, Tnni3k, TNNI3 interacting kinase, [Score=82.4, Expect=5e-16]} {Dmel: FBgn0031473, CG3104, [Score=82.4, Expect=5e-17]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=74.7, Expect=8e-14]} {Smed: dd_Smed_v6_9936_0_1, dd_Smed_v6_9936_0_1, [Score=77.8, Expect=5e-15]} {RNA1509_26004} {RNA1310_3906.1} {RNA815_1664.1}
8. MligTC455_29971 111 2.31 Mlig455_006512

Neo: -

Age: -

 CRB2 1.791 - - - 0.826 0.965 - Mlig455_006512 {REF} {Length: 4810} {Pfam: EGF-like domain [PF00008.29, score=148.0]; Human growth factor-like EGF [PF12661.9, score=63.1]; Laminin G domain [PF02210.26, score=25.7]} {Human: ENSG00000148204, CRB2, crumbs 2, cell polarity complex component, [RH, Score=360, Expect=8e-105]} {Mouse: ENSMUSG00000035403, Crb2, crumbs family member 2, [RH, Score=358, Expect=3e-104]} {Dmel: FBgn0259685, crb, crumbs, [Score=412, Expect=2e-120]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=201, Expect=5e-52]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [Score=230, Expect=3e-61]} {RNA1509_50019} {RNA1310_14888.1} {RNA815_693.1}
9. MligTC455_21774 61 1.27 Mlig455_027485

Neo: -

Age: -

 1.771 - - - - 0.787 0.984 Mlig455_027485 {REF} {Length: 570} {NoTransDecoderORF} {RNA1509_59553} {RNA1310_6578} {RNA815_41194.1}
10. MligTC455_40360 564 11.75 Mlig455_060950

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=3.425

Regeneration-enriched R5: 6.585
Regeneration-enriched R2: 5.085

 AGRN 1.758 - - 0.989 0.769 - - Mlig455_060950 {REF} {Length: 1959} {Pfam: Kazal-type serine protease inhibitor domain [PF00050.23, score=110.8]; Kazal-type serine protease inhibitor domain [PF07648.17, score=94.2]} {Human: ENSG00000188157, AGRN, agrin, [Score=58.2, Expect=3e-08]} {Mouse: ENSMUSG00000041936, Agrn, agrin, [Score=54.7, Expect=3e-07]} {Celegans: WBGene00009257, F29G6.1, [Score=48.9, Expect=8e-06]} {Smed: dd_Smed_v6_3649_0_1, dd_Smed_v6_3649_0_1, [Score=51.2, Expect=1e-06]} {RNA1509_43736} {RNA1310_19594} {RNA815_11515}
11. MligTC455_11644 18 0.37 Mlig455_034785

Neo: -

Age: -

 1.722 - - - - 0.772 0.950 Mlig455_034785 {REF} {Length: 982} {NoTransDecoderORF}
12. MligTC455_12302 137 2.85 Mlig455_001240

Neo: -

Age: -

 1.673 - - - - 0.706 0.967 Mlig455_001240 {REF} {Length: 441} {NoTransDecoderORF} {RNA1509_35425} {RNA1310_32078} {RNA815_40733}
13. MligTC455_10909 52 1.09 Mlig455_066581

Neo: -

Age: -

 1.661 - - - - 0.709 0.952 Mlig455_066581 {REF} {Length: 739} {NoTransDecoderORF}
14. MligTC455_21762 134 2.8 Mlig455_031432

Neo: -

Age: -

 0.975 - - - - 0.975 - Mlig455_031432 {REF} {Length: 284} {NoTransDecoderORF} {RNA1509_42914} {RNA1310_99471} {RNA815_64986}
15. MligTC455_57148 12 0.24 Mlig455_017544

Neo: -

Age: -

 0.974 - - - - - 0.974 Mlig455_017544 {REF} {Length: 195} {NoTransDecoderORF} {RNA1310_40177}
16. MligTC455_24999 23 0.47 Mlig455_016811

Neo: -

Age: Up-Down-Up

 0.97 - - - - - 0.970 Mlig455_016811 {REF} {Length: 4916} {Pfam: Receptor family ligand binding region [PF01094.30, score=68.5]} {RNA1509_21912} {RNA1310_5718} {RNA815_6955}
17. MligTC455_01695 25 0.52 Mlig455_015208

Neo: -

Age: -

 0.968 - - - - - 0.968 Mlig455_015208 {REF} {Length: 605} {NoTransDecoderORF} {RNA1509_45595} {RNA1310_13430.1} {RNA815_343.1}
18. MligTC455_13722 93 1.93 Mlig455_039921, Mlig455_041209

Neo: -

Age: -

Regeneration-upregulated R2: 6.355

Regeneration-enriched R2: 6.355

 0.968 - - - - - 0.968

Mlig455_039921 {REF} {Length: 2452} {Pfam: Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=45.3]; 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=32.9]} {Smed: dd_Smed_v6_14726_0_1, dd_Smed_v6_14726_0_1, [Score=85.9, Expect=1e-18]} {RNA1310_95524.1} {RNA815_48018}

Mlig455_041209 {REF} {Length: 3316} {Pfam: Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=45.3]; 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=32.9]} {Smed: dd_Smed_v6_14726_0_1, dd_Smed_v6_14726_0_1, [Score=85.9, Expect=1e-18]} {RNA1310_95524.1} {RNA815_48018}
19. MligTC455_42532 23 0.48 Mlig455_043488

Neo: -

Age: Up-Down-Down

 0.966 - - - - 0.966 - Mlig455_043488 {REF} {Length: 1588} {NoTransDecoderORF} {RNA1509_28941} {RNA1310_12423} {RNA815_12549.1}
20. MligTC455_01670 53 1.1 Mlig455_064916

Neo: -

Age: -

 0.965 - - - - - 0.965 Mlig455_064916 {REF} {Length: 1064} {NoTransDecoderORF} {RNA1310_37680}
21. MligTC455_29678 117 2.43 Mlig455_022431

Neo: -

Age: Down-Up-Down

 ANKRD50 0.962 - - - - - 0.962 Mlig455_022431 {REF} {Length: 7082} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=155.6]; Ankyrin repeats (many copies) [PF13637.8, score=151.3]; Ankyrin repeat [PF13606.8, score=83.7]; Ankyrin repeats (many copies) [PF13857.8, score=76.9]; HEAT repeats [PF13646.8, score=54.2]; Ankyrin repeat [PF00023.32, score=44.3]; Mab-21 protein [PF03281.16, score=41.3]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=89.0, Expect=5e-17]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=91.7, Expect=5e-18]} {Dmel: FBgn0041096, rols, rolling pebbles, [Score=71.6, Expect=5e-12]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=74.3, Expect=7e-13]} {Smed: dd_Smed_v6_13721_0_1, dd_Smed_v6_13721_0_1, [Score=77.0, Expect=7e-14]} {RNA1509_7687} {RNA1310_4721} {RNA815_5358.1}
22. MligTC455_02874 59 1.22 Mlig455_019845

Neo: -

Age: -

Regeneration-enriched R3: 8.664
Regeneration-enriched R5: 7.271
Regeneration-enriched R2: 5.909

 0.961 - - - - 0.961 - Mlig455_019845 {REF} {Length: 705} {NoTransDecoderORF}
23. MligTC455_18454 37 0.78 Mlig455_025691

Neo: -

Age: -

Region-enriched R2: 4.778/0.02984

 0.961 - - - - - 0.961 Mlig455_025691 {REF} {Length: 1813} {RNA1310_101808}
24. MligTC455_28060 21 0.43 Mlig455_034155

Neo: -

Age: -

 NEK8 0.96 - - - - - 0.960 Mlig455_034155 {REF} {Length: 1685} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=183.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=133.0]; Kinase-like [PF14531.8, score=25.3]; Phosphotransferase enzyme family [PF01636.25, score=23.6]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=19.1]; ABC1 atypical kinase-like domain [PF03109.18, score=19.0]} {Human: ENSG00000160602, NEK8, NIMA related kinase 8, [Score=186, Expect=3e-53]} {Mouse: ENSMUSG00000017405, Nek8, NIMA (never in mitosis gene a)-related expressed kinase 8, [Score=181, Expect=3e-51]; ENSMUSG00000021918, Nek4, NIMA (never in mitosis gene a)-related expressed kinase 4, [Score=178, Expect=5e-50]} {Dmel: FBgn0045980, niki, nimA-like kinase, [Score=162, Expect=2e-44]} {Celegans: WBGene00022631, nekl-2, Serine/threonine-protein kinase nekl-2, [Score=169, Expect=8e-50]} {Smed: dd_Smed_v6_9098_0_1, dd_Smed_v6_9098_0_1, [Score=158, Expect=7e-44]} {RNA1509_55524} {RNA1310_31447.2} {RNA815_35931}
25. MligTC455_30228 51 1.07 Mlig455_006181, Mlig455_030077, Mlig455_036075, Mlig455_036097, Mlig455_049726, Mlig455_070542

Neo: -

Age: -

Region-enriched R5: 3.456/0.03276

 PIF1 0.958 - - - - 0.958 -

Mlig455_006181 {REF} {Length: 5128} {Pfam: PIF1-like helicase [PF05970.16, score=232.2]; Helitron helicase-like domain at N-terminus [PF14214.8, score=175.6]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=52.4, Expect=5e-06]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=52.0, Expect=5e-06]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=59.7, Expect=1e-08]} {Celegans: WBGene00019136, F59H6.5, [Score=565, Expect=2e-178]} {Smed: dd_Smed_v6_91935_0_1, dd_Smed_v6_91935_0_1, [Score=68.2, Expect=2e-13]} {RNA1509_5036} {RNA1310_4048.1} {RNA815_356.1}

Mlig455_030077 {REF} {Length: 6580} {Pfam: Helitron helicase-like domain at N-terminus [PF14214.8, score=175.5]} {Celegans: WBGene00019136, F59H6.5, [Score=412, Expect=6e-125]} {Smed: dd_Smed_v6_5211_0_1, dd_Smed_v6_5211_0_1, [Score=72.4, Expect=4e-14]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_036075 {REF} {Length: 5097} {TRANSSPLICED} {Pfam: PIF1-like helicase [PF05970.16, score=332.7]; Helitron helicase-like domain at N-terminus [PF14214.8, score=170.5]; AAA domain [PF13604.8, score=44.2]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.3]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=124, Expect=3e-28]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=118, Expect=2e-26]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=121, Expect=1e-27]} {Celegans: WBGene00019136, F59H6.5, [RH, Score=783, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=114, Expect=1e-25]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_036097 {REF} {Length: 5327} {TRANSSPLICED} {Pfam: PIF1-like helicase [PF05970.16, score=332.5]; Helitron helicase-like domain at N-terminus [PF14214.8, score=170.4]; AAA domain [PF13604.8, score=44.1]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.2]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=124, Expect=3e-28]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=118, Expect=1e-26]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=120, Expect=2e-27]} {Celegans: WBGene00019136, F59H6.5, [RH, Score=770, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=114, Expect=1e-25]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_049726 {REF} {Length: 5322} {Pfam: PIF1-like helicase [PF05970.16, score=328.1]; Helitron helicase-like domain at N-terminus [PF14214.8, score=171.9]; AAA domain [PF13604.8, score=44.8]; UvrD-like helicase C-terminal domain [PF13538.8, score=24.3]; Helicase [PF02689.16, score=17.1]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=122, Expect=9e-28]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=118, Expect=2e-26]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=118, Expect=9e-27]} {Celegans: WBGene00021194, Y16E11A.2, [Score=723, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=114, Expect=1e-25]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_070542 {REF} {Length: 5678} {Pfam: PIF1-like helicase [PF05970.16, score=334.4]; Helitron helicase-like domain at N-terminus [PF14214.8, score=173.4]; AAA domain [PF13604.8, score=46.0]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.3]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=125, Expect=2e-28]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=120, Expect=4e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=120, Expect=2e-27]} {Celegans: WBGene00019136, F59H6.5, [Score=765, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=116, Expect=2e-26]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}
26. MligTC455_45429 764 15.92 Mlig455_000855

Neo: -

Age: -

 CAND1 0.958 - - - - 0.958 - Mlig455_000855 {REF} {Length: 5555} {Pfam: TATA-binding protein interacting (TIP20) [PF08623.12, score=154.4]; Adaptin N terminal region [PF01602.22, score=39.6]; HEAT repeats [PF13646.8, score=33.6]; UME (NUC010) domain [PF08064.15, score=25.1]} {Human: ENSG00000111530, CAND1, cullin associated and neddylation dissociated 1, [RH, Score=895, Expect=0.0]} {Mouse: ENSMUSG00000020114, Cand1, cullin associated and neddylation disassociated 1, [RH, Score=892, Expect=0.0]} {Dmel: FBgn0027568, Cand1, Cullin-associated and neddylation-dissociated 1, [RH, Score=796, Expect=0.0]} {Celegans: WBGene00013606, cand-1, Cullin-associated NEDD8-dissociated protein 1, [RH, Score=466, Expect=1e-141]} {Smed: dd_Smed_v6_6507_0_1, dd_Smed_v6_6507_0_1, [RH, Score=629, Expect=0.0]} {RNA1509_16395, RNA1509_4060} {RNA1310_1644.1, RNA1509_16395} {RNA1509_16395, RNA815_456}
27. MligTC455_46886 51 1.05 Mlig455_015258

Neo: -

Age: -

Region-enriched R2: 4.468/0.04690

 PRKG2 0.958 - - - - - 0.958 Mlig455_015258 {REF} {Length: 3110} {Pfam: Protein kinase domain [PF00069.27, score=225.4]; Cyclic nucleotide-binding domain [PF00027.31, score=118.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=117.9]; Kinase-like [PF14531.8, score=25.3]} {Human: ENSG00000138669, PRKG2, protein kinase cGMP-dependent 2, [RH, Score=668, Expect=0.0]} {Mouse: ENSMUSG00000029334, Prkg2, protein kinase, cGMP-dependent, type II, [RH, Score=669, Expect=0.0]} {Dmel: FBgn0000442, Pkg21D, Protein kinase, cGMP-dependent at 21D, [RH, Score=683, Expect=0.0]} {Celegans: WBGene00001173, egl-4, cGMP-dependent protein kinase egl-4, [Score=667, Expect=0.0]} {Smed: dd_Smed_v6_6967_0_1, dd_Smed_v6_6967_0_1, [RH, Score=672, Expect=0.0]} {RNA1509_26653} {RNA1310_15330.1} {RNA815_26005}
28. MligTC455_10078 251 5.22 Mlig455_005645, Mlig455_005691

Neo: -

Age: -

Region-enriched R4: 5.505/0.00346

 0.957 - - - - - 0.957

Mlig455_005645 {REF} {Length: 1477} {Smed: dd_Smed_v6_10422_0_4, dd_Smed_v6_10422_0_4, [Score=47.8, Expect=4e-07]}

Mlig455_005691 {REF} {Length: 742} {Smed: dd_Smed_v6_10422_0_4, dd_Smed_v6_10422_0_4, [Score=47.8, Expect=4e-07]}
29. MligTC455_16399 79 1.65 Mlig455_020491

Neo: -

Age: -

 0.957 - - 0.957 - - - Mlig455_020491 {REF} {Length: 1238} {TRANSSPLICED} {RNA1509_33940} {RNA1310_6782.1} {RNA815_4292}
30. MligTC455_27080 48 1 Mlig455_061810

Neo: -

Age: -

 0.956 - - - - 0.956 - Mlig455_061810 {REF} {Length: 665} {RNA1509_44223} {RNA1310_99471} {RNA815_64986}
31. MligTC455_28998 88 1.83 Mlig455_007313

Neo: -

Age: -

 0.954 - - - - 0.954 - Mlig455_007313 {REF} {Length: 2647} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=63.3]} {Smed: dd_Smed_v6_13734_0_20, dd_Smed_v6_13734_0_20, [Score=51.6, Expect=2e-07]} {RNA1509_13072} {RNA1310_4523} {RNA815_17419}
32. MligTC455_04358 40 0.83 Mlig455_061396

Neo: -

Age: -

Region-enriched R7: 4.622/0.01812

 0.953 - - - - 0.953 - Mlig455_061396 {REF} {Length: 963} {RNA1509_36436} {RNA1310_57166} {RNA815_43432}
33. MligTC455_12438 17 0.35 Mlig455_009594

Neo: -

Age: -

 0.953 - - - - - 0.953 Mlig455_009594 {REF} {Length: 2044} {RNA1310_39190} {RNA815_29274}
34. MligTC455_21681 27 0.56 Mlig455_004824, Mlig455_004903

Neo: -

Age: -

 0.952 - - - - - 0.952

Mlig455_004824 {REF} {Length: 1006} {Pfam: Lectin C-type domain [PF00059.23, score=26.8]} {Mouse: ENSMUSG00000065987, Cd209b, CD209b antigen, [Score=50.1, Expect=7e-07]; ENSMUSG00000079168, Cd209g, CD209g antigen, [Score=48.1, Expect=2e-06]} {Smed: dd_Smed_v6_85740_0_1, dd_Smed_v6_85740_0_1, [Score=52.0, Expect=1e-08]} {RNA1310_61965} {RNA815_21285}

Mlig455_004903 {REF} {Length: 1008} {Pfam: Lectin C-type domain [PF00059.23, score=26.8]} {Mouse: ENSMUSG00000065987, Cd209b, CD209b antigen, [Score=50.1, Expect=7e-07]; ENSMUSG00000079168, Cd209g, CD209g antigen, [Score=48.1, Expect=2e-06]} {Smed: dd_Smed_v6_85740_0_1, dd_Smed_v6_85740_0_1, [Score=52.0, Expect=1e-08]} {RNA1310_61965} {RNA815_21285}
35. MligTC455_54002 39320 819.17 Mlig455_062577

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.908

Region-enriched R2: 1.076/0.02199

 HPGDS 0.952 - - - - 0.952 - Mlig455_062577 {REF} {Length: 1344} {TRANSSPLICED} {Pfam: Glutathione S-transferase, C-terminal domain [PF14497.8, score=60.6]; Glutathione S-transferase, N-terminal domain [PF02798.22, score=30.5]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=22.7]} {Human: ENSG00000163106, HPGDS, hematopoietic prostaglandin D synthase, [RH, Score=104, Expect=2e-27]} {Mouse: ENSMUSG00000029919, Hpgds, hematopoietic prostaglandin D synthase, [RH, Score=90.5, Expect=2e-22]} {Celegans: WBGene00001759, gst-11, Glutathione S-Transferase, [Score=98.2, Expect=1e-25]} {Smed: dd_Smed_v6_20_0_1, dd_Smed_v6_20_0_1, [Score=176, Expect=4e-56]} {RNA1509_1453, RNA1509_20209, RNA1509_21721, RNA1509_2315, RNA1509_2503, RNA1509_26173, RNA1509_28962, RNA1509_31321, RNA1509_52612} {RNA1310_24762, RNA1509_1453, RNA1509_20209, RNA1509_21721, RNA1509_2315, RNA1509_2503, RNA1509_26173, RNA1509_28962, RNA1509_31321, RNA1509_52612} {RNA1509_1453, RNA1509_20209, RNA1509_21721, RNA1509_2315, RNA1509_2503, RNA1509_26173, RNA1509_28962, RNA1509_31321, RNA1509_52612, RNA815_10524}
36. MligTC455_29170 61 1.27 Mlig455_006854

Neo: -

Age: Up-Down-Up

 ANKRD28 0.951 - - - - - 0.951 Mlig455_006854 {REF} {Length: 6646} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=545.1]; Ankyrin repeats (many copies) [PF13637.8, score=445.2]; Ankyrin repeats (many copies) [PF13857.8, score=362.4]; Ankyrin repeat [PF13606.8, score=333.1]; Ankyrin repeat [PF00023.32, score=286.9]; Protein kinase domain [PF00069.27, score=49.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=38.2]} {Human: ENSG00000206560, ANKRD28, ankyrin repeat domain 28, [Score=249, Expect=5e-67]; ENSG00000145362, ANK2, ankyrin 2, [Score=241, Expect=4e-63]} {Mouse: ENSMUSG00000014496, Ankrd28, ankyrin repeat domain 28, [Score=252, Expect=6e-68]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=216, Expect=1e-56]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=225, Expect=7e-59]} {Smed: dd_Smed_v6_5303_0_2, dd_Smed_v6_5303_0_2, [Score=232, Expect=1e-62]} {RNA1509_19358} {RNA1310_610.2} {RNA815_1111.1}
37. MligTC455_07484 67 1.39 Mlig455_010287, Mlig455_065668, Mlig455_065669

Neo: -

Age: logFC(26M/2M)=-0.660

 GRID1, GRIK4 0.95 - - - 0.950 - -

Mlig455_010287 {REF} {Length: 3136} {Pfam: Ligand-gated ion channel [PF00060.28, score=95.1]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=49.7]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=31.1]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=151, Expect=4e-37]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=147, Expect=5e-36]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=146, Expect=2e-35]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=148, Expect=3e-36]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=147, Expect=3e-36]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=146, Expect=9e-36]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=142, Expect=3e-34]; ENSMUSG00000003378, Grik5, glutamate receptor, ionotropic, kainate 5 (gamma 2), [Score=141, Expect=4e-34]} {Dmel: FBgn0038837, CG3822, [Score=172, Expect=2e-44]} {Celegans: WBGene00001615, glr-4, GLutamate Receptor family (AMPA), [Score=125, Expect=2e-29]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=274, Expect=1e-84]} {RNA1509_59035} {RNA1310_5145.1} {RNA815_9565}

Mlig455_065668 {REF} {Length: 3710} {Pfam: Ligand-gated ion channel [PF00060.28, score=94.0]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=49.5]; Receptor family ligand binding region [PF01094.30, score=36.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=30.8]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=150, Expect=1e-36]; ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=149, Expect=4e-36]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=148, Expect=5e-36]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=145, Expect=3e-35]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=144, Expect=8e-35]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=147, Expect=5e-36]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=147, Expect=6e-36]; ENSMUSG00000041078, Grid1, glutamate receptor, ionotropic, delta 1, [Score=146, Expect=1e-35]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=145, Expect=2e-35]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=144, Expect=8e-35]; ENSMUSG00000003378, Grik5, glutamate receptor, ionotropic, kainate 5 (gamma 2), [Score=141, Expect=6e-34]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=140, Expect=1e-33]} {Dmel: FBgn0038837, CG3822, [Score=172, Expect=3e-44]} {Celegans: WBGene00001615, glr-4, GLutamate Receptor family (AMPA), [Score=125, Expect=2e-29]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=274, Expect=3e-84]} {RNA1509_59035} {RNA1310_5145.1} {RNA815_7506}

Mlig455_065669 {REF} {Length: 2221} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=44.0]; Ligand-gated ion channel [PF00060.28, score=38.3]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=22.8]} {Human: ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=58.2, Expect=2e-08]; ENSG00000152208, GRID2, glutamate ionotropic receptor delta type subunit 2, [Score=56.6, Expect=7e-08]} {Mouse: ENSMUSG00000041078, Grid1, glutamate receptor, ionotropic, delta 1, [Score=57.8, Expect=2e-08]; ENSMUSG00000071424, Grid2, glutamate receptor, ionotropic, delta 2, [Score=56.6, Expect=5e-08]} {Dmel: FBgn0046113, GluRIIC, Glutamate receptor IIC, [Score=56.6, Expect=3e-08]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=48.9, Expect=6e-06]} {Smed: dd_Smed_v6_33317_0_1, dd_Smed_v6_33317_0_1, [Score=99.8, Expect=2e-23]} {RNA1509_59035} {RNA1310_5145.1} {RNA815_7506}
38. MligTC455_13251 89 1.86 Mlig455_005191

Neo: -

Age: logFC(26M/2M)=-0.503

 0.95 - - - - 0.950 - Mlig455_005191 {REF} {Length: 651} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=36.6]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=41.2, Expect=9e-06]} {RNA1509_40279} {RNA1310_35227} {RNA815_50075}
39. MligTC455_21813 524 10.92 Mlig455_006857

Neo: -

Age: -

 QRICH2 0.95 - - - - 0.950 - Mlig455_006857 {REF} {Length: 4774} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4795) [PF16043.7, score=162.6]} {Human: ENSG00000129646, QRICH2, glutamine rich 2, [Score=157, Expect=6e-39]} {Mouse: ENSMUSG00000070331, Qrich2, glutamine rich 2, [RH, Score=160, Expect=3e-41]} {Dmel: FBgn0031347, CG10869, [RH, Score=67.0, Expect=4e-11]} {Smed: dd_Smed_v6_6048_0_3, dd_Smed_v6_6048_0_3, [RH, Score=554, Expect=0.0]} {RNA1509_53937, RNA1509_56910} {RNA1310_3031.1, RNA1509_53937} {RNA1509_53937, RNA815_1272.1}
40. MligTC455_51298 56 1.17 Mlig455_004013

Neo: -

Age: -

 NCOR1 0.95 - - - - 0.950 - Mlig455_004013 {REF} {Length: 4600} {TRANSSPLICED} {Pfam: Myb-like DNA-binding domain [PF00249.33, score=23.2]} {Human: ENSG00000141027, NCOR1, nuclear receptor corepressor 1, [Score=177, Expect=5e-44]; ENSG00000196498, NCOR2, nuclear receptor corepressor 2, [Score=173, Expect=1e-42]} {Mouse: ENSMUSG00000018501, Ncor1, nuclear receptor co-repressor 1, [Score=177, Expect=4e-44]; ENSMUSG00000029478, Ncor2, nuclear receptor co-repressor 2, [Score=176, Expect=1e-43]} {Dmel: FBgn0265523, Smr, Smrter, [Score=169, Expect=1e-41]} {Smed: dd_Smed_v6_7709_0_1, dd_Smed_v6_7709_0_1, [Score=185, Expect=3e-47]} {RNA1509_55924} {RNA1310_3476.1} {RNA815_1593}

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