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Results for MligTC455_40790

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_40790 212 4.43 Mlig455_032027

Neo: Irradiation

Age: Up-Down-Down

Region-enriched R2: 2.642/0.01234

PDE11A Mlig455_032027 {REF} {Length: 3463} {Pfam: 3'5'-cyclic nucleotide phosphodiesterase [PF00233.21, score=143.6]; GAF domain [PF01590.28, score=84.0]; GAF domain [PF13185.8, score=50.1]; GAF domain [PF13492.8, score=44.7]} {Human: ENSG00000128655, PDE11A, phosphodiesterase 11A, [Score=407, Expect=3e-128]; ENSG00000138735, PDE5A, phosphodiesterase 5A, [Score=405, Expect=4e-128]} {Mouse: ENSMUSG00000075270, Pde11a, phosphodiesterase 11A, [Score=405, Expect=1e-127]; ENSMUSG00000053965, Pde5a, phosphodiesterase 5A, cGMP-specific, [Score=404, Expect=5e-128]} {Dmel: FBgn0085370, Pde11, Phosphodiesterase 11, [Score=417, Expect=1e-130]} {Celegans: WBGene00016328, pde-5, Probable 3',5'-cyclic phosphodiesterase pde-5, [Score=232, Expect=1e-65]} {Smed: dd_Smed_v6_8595_0_4, dd_Smed_v6_8595_0_4, [Score=441, Expect=6e-142]} {RNA1509_52520} {RNA1310_8630.1, RNA1509_52520} {RNA1509_52520, RNA815_26873}

Cumulative graph for MligTC455_40790

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 1.102 2.306 0.40156 1.00000
RegionR2 2.642 2.306 0.00045 0.01234
RegionR3 0.838 2.306 0.25989 0.80352
RegionR4 1.311 2.306 0.05090 0.19514
RegionR5 -1.234 2.306 0.98818 1.00000
RegionR6 0.164 2.306 0.66691 1.00000
RegionR7 -5.333 2.306 0.02059 0.26652
RegionR8 0.509 2.306 0.57355 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -6.921 2.306 0.10021 0.81679
RegenerationR2 -0.197 2.306 0.68367 0.95001
RegenerationR3 -0.695 2.306 0.33994 0.76428
RegenerationR4 -1.192 2.306 0.04883 0.35644
RegenerationR5 0.984 2.306 0.19668 0.62879
RegenerationR6 -0.153 2.306 0.85996 1.00000
RegenerationBL -0.144 2.306 0.78317 1.00000
RegenerationTP 2.71 2.306 0.10009 0.49221


Genes with expression patterns similar to MligTC455_40790

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_40790 212 4.43 Mlig455_032027

Neo: Irradiation

Age: Up-Down-Down

Region-enriched R2: 2.642/0.01234

PDE11A 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_032027 {REF} {Length: 3463} {Pfam: 3'5'-cyclic nucleotide phosphodiesterase [PF00233.21, score=143.6]; GAF domain [PF01590.28, score=84.0]; GAF domain [PF13185.8, score=50.1]; GAF domain [PF13492.8, score=44.7]} {Human: ENSG00000128655, PDE11A, phosphodiesterase 11A, [Score=407, Expect=3e-128]; ENSG00000138735, PDE5A, phosphodiesterase 5A, [Score=405, Expect=4e-128]} {Mouse: ENSMUSG00000075270, Pde11a, phosphodiesterase 11A, [Score=405, Expect=1e-127]; ENSMUSG00000053965, Pde5a, phosphodiesterase 5A, cGMP-specific, [Score=404, Expect=5e-128]} {Dmel: FBgn0085370, Pde11, Phosphodiesterase 11, [Score=417, Expect=1e-130]} {Celegans: WBGene00016328, pde-5, Probable 3',5'-cyclic phosphodiesterase pde-5, [Score=232, Expect=1e-65]} {Smed: dd_Smed_v6_8595_0_4, dd_Smed_v6_8595_0_4, [Score=441, Expect=6e-142]} {RNA1509_52520} {RNA1310_8630.1, RNA1509_52520} {RNA1509_52520, RNA815_26873}
2. MligTC455_23543 79 1.65 Mlig455_021851

Neo: -

Age: -

Region-enriched R2: 5.153/0.00077

MAP3K19 3.495 0.773 - - 0.939 0.960 0.823 Mlig455_021851 {REF} {Length: 7454} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=226.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=217.3]; Ankyrin repeats (3 copies) [PF12796.9, score=113.8]; Ankyrin repeats (many copies) [PF13637.8, score=82.7]; Ankyrin repeats (many copies) [PF13857.8, score=77.3]; F5/8 type C domain [PF00754.27, score=56.3]; Ankyrin repeat [PF00023.32, score=55.9]; Ankyrin repeat [PF13606.8, score=49.9]; ABC1 atypical kinase-like domain [PF03109.18, score=28.7]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=159, Expect=2e-40]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=164, Expect=3e-42]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=146, Expect=1e-35]} {Celegans: WBGene00001526, gck-1, Germinal center kinase 1, [Score=139, Expect=2e-33]} {Smed: dd_Smed_v6_10339_0_1, dd_Smed_v6_10339_0_1, [Score=153, Expect=2e-37]} {RNA1509_46581} {RNA1310_9191} {RNA815_12161}
3. MligTC455_41471 131 2.72 Mlig455_040252, Mlig455_054698

Neo: -

Age: -

Region-enriched R2: 3.576/0.00566

ANGPTL1 2.734 - - 0.941 - 0.950 0.843

Mlig455_040252 {REF} {Length: 2778} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=120.9]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=112, Expect=2e-27]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=107, Expect=2e-25]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=109, Expect=2e-26]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=107, Expect=1e-25]} {Dmel: FBgn0050280, CG30280, [Score=93.6, Expect=5e-22]} {Celegans: WBGene00020516, T15B7.1, [Score=61.6, Expect=1e-10]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=100, Expect=9e-24]} {RNA1509_57196} {RNA1310_23214} {RNA815_19964}

Mlig455_054698 {REF} {Length: 3143} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=127.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=108, Expect=4e-26]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=105, Expect=6e-25]; ENSG00000160339, FCN2, ficolin 2, [Score=103, Expect=3e-25]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=105, Expect=3e-25]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=105, Expect=4e-25]; ENSMUSG00000026835, Fcnb, ficolin B, [Score=103, Expect=5e-25]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=103, Expect=2e-24]; ENSMUSG00000042436, Mfap4, microfibrillar-associated protein 4, [Score=102, Expect=4e-25]; ENSMUSG00000015829, Tnr, tenascin R, [Score=102, Expect=7e-24]; ENSMUSG00000026938, Fcna, ficolin A, [Score=102, Expect=9e-25]} {Dmel: FBgn0050280, CG30280, [Score=97.8, Expect=1e-23]} {Celegans: WBGene00020516, T15B7.1, [Score=62.0, Expect=9e-11]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=100, Expect=2e-23]} {RNA1310_23214} {RNA815_19964}
4. MligTC455_26356 62 1.3 Mlig455_042551

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.548

GRIK2 2.692 - - 0.938 - 0.964 0.790 Mlig455_042551 {REF} {Length: 2917} {Pfam: Ligand-gated ion channel [PF00060.28, score=82.2]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=60.7]; Receptor family ligand binding region [PF01094.30, score=32.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=27.3]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=144, Expect=9e-35]; ENSG00000152208, GRID2, glutamate ionotropic receptor delta type subunit 2, [Score=141, Expect=7e-34]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=143, Expect=1e-34]; ENSMUSG00000071424, Grid2, glutamate receptor, ionotropic, delta 2, [Score=142, Expect=2e-34]} {Dmel: FBgn0051201, GluRIIE, Glutamate receptor IIE, [Score=119, Expect=3e-27]} {Celegans: WBGene00001616, glr-5, GLutamate Receptor family (AMPA), [Score=123, Expect=2e-28]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=247, Expect=4e-74]} {RNA1310_21865} {RNA815_26044}
5. MligTC455_17138 283 5.89 Mlig455_029728

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.646

Region-specific R2: 4.824

Region-enriched R2: 5.583/0.00000

LRRCC1 2.672 - - - 0.843 0.954 0.875 Mlig455_029728 {REF} {Length: 1372} {Pfam: Heat shock factor binding protein 1 [PF06825.14, score=68.1]; Leucine Rich repeats (2 copies) [PF12799.9, score=67.8]; Leucine rich repeat [PF13855.8, score=44.9]; Leucine-rich repeat [PF14580.8, score=35.0]; Leucine Rich repeat [PF13516.8, score=21.5]} {Human: ENSG00000133739, LRRCC1, leucine rich repeat and coiled-coil centrosomal protein 1, [RH, Score=402, Expect=3e-122]} {Mouse: ENSMUSG00000027550, Lrrcc1, leucine rich repeat and coiled-coil domain containing 1, [RH, Score=387, Expect=3e-117]} {Dmel: FBgn0032429, CG5446, [Score=66.6, Expect=3e-13]} {Celegans: WBGene00189952, K10D2.8, [Score=65.1, Expect=8e-11]} {Smed: dd_Smed_v6_10086_0_1, dd_Smed_v6_10086_0_1, [RH, Score=443, Expect=2e-139]} {RNA1509_31405, RNA1509_32465} {RNA1310_70756, RNA1509_31405, RNA1509_32465} {RNA1509_31405, RNA1509_32465, RNA815_37567}
6. MligTC455_46584 107 2.22 Mlig455_010128

Neo: -

Age: Up-Down-Down

KCNC2 2.664 - - 0.933 0.773 0.958 - Mlig455_010128 {REF} {Length: 1706} {Human: ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=74.3, Expect=3e-15]} {Mouse: ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=74.3, Expect=3e-16]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=114, Expect=3e-29]} {Celegans: WBGene00001202, egl-36, Potassium voltage-gated channel protein egl-36, [Score=100, Expect=1e-24]} {Smed: dd_Smed_v6_17998_0_1, dd_Smed_v6_17998_0_1, [Score=118, Expect=1e-32]} {RNA1310_24374} {RNA815_11270}
7. MligTC455_13102 65 1.35 Mlig455_056246

Neo: -

Age: Up-Down-Down

Region-enriched R2: 6.206/0.00027

NWD2 2.648 - 0.885 - - 0.973 0.790 Mlig455_056246 {REF} {Length: 8104} {Pfam: NACHT domain [PF05729.14, score=51.2]; AAA ATPase domain [PF13191.8, score=36.8]; Domain of unknown function (DUF4062) [PF13271.8, score=36.5]; ATPase domain predominantly from Archaea [PF01637.20, score=23.7]; AAA domain [PF13401.8, score=20.6]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=451, Expect=2e-130]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [RH, Score=436, Expect=2e-125]} {Dmel: FBgn0038397, CG10185, [RH, Score=980, Expect=0.0]} {Celegans: WBGene00020254, T05C3.2, [RH, Score=925, Expect=0.0]} {Smed: dd_Smed_v6_11085_0_1, dd_Smed_v6_11085_0_1, [Score=344, Expect=9e-96]} {RNA1509_20730} {RNA1310_1147} {RNA815_11922}
8. MligTC455_53435 190 3.96 Mlig455_045425, Mlig455_065748

Neo: -

Age: -

Region-enriched R2: 4.111/0.00023

SYT9 2.644 - - - 0.805 0.951 0.888

Mlig455_045425 {REF} {Length: 2615} {RNA1509_46689} {RNA1310_15031, RNA1509_46689} {RNA1509_46689, RNA815_18779.1}

Mlig455_065748 {REF} {Length: 3143} {Pfam: C2 domain [PF00168.32, score=116.1]} {Human: ENSG00000170743, SYT9, synaptotagmin 9, [Score=162, Expect=4e-42]; ENSG00000213023, SYT3, synaptotagmin 3, [Score=157, Expect=5e-40]} {Mouse: ENSMUSG00000062542, Syt9, synaptotagmin IX, [Score=162, Expect=3e-42]; ENSMUSG00000030731, Syt3, synaptotagmin III, [Score=156, Expect=1e-39]} {Dmel: FBgn0261089, Sytalpha, Synaptotagmin alpha, [RH, Score=197, Expect=1e-54]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=144, Expect=8e-37]} {Smed: dd_Smed_v6_6730_0_1, dd_Smed_v6_6730_0_1, [Score=155, Expect=5e-41]} {RNA1509_46689} {RNA1310_15031} {RNA815_18779.1}
9. MligTC455_35945 130 2.71 Mlig455_065474

Neo: -

Age: Up-Down-Up

2.628 - - 0.844 - 0.970 0.814 Mlig455_065474 {REF} {Length: 1654} {RNA1310_22530} {RNA815_54411}
10. MligTC455_51314 525 10.93 Mlig455_017296, Mlig455_045285

Neo: -

Age: -

Region-enriched R2: 2.314/0.04004
Region-enriched R6: 2.112/0.04352

2.572 - - - 0.967 0.875 0.730

Mlig455_017296 {REF} {Length: 2087} {RNA1310_34789} {RNA815_64894}

Mlig455_045285 {REF} {Length: 1644} {RNA1310_34789} {RNA815_64894}
11. MligTC455_49825 543 11.31 Mlig455_069114

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.806

Region-enriched R2: 3.936/0.00000

2.555 - - 0.793 - 0.952 0.810 Mlig455_069114 {REF} {Length: 828} {Celegans: WBGene00003748, nlp-10, Neuropeptide-Like Protein, [Score=40.0, Expect=9e-06]} {RNA1509_26665} {RNA1310_48731, RNA1509_26665} {RNA1509_26665, RNA815_24488}
12. MligTC455_14483 140 2.92 Mlig455_028240

Neo: -

Age: -

Region-enriched R2: 6.203/0.04837

2.553 - - 0.780 - 0.964 0.809 Mlig455_028240 {REF} {Length: 728} {RNA1310_111517} {RNA815_9716}
13. MligTC455_16329 1019 21.23 Mlig455_007993

Neo: -

Age: -

Region-specific R2: 3.685

Region-enriched R2: 3.576/0.00000
Region-enriched R7: 1.704/0.00652

2.533 - - - 0.711 0.960 0.862 Mlig455_007993 {REF} {Length: 635} {RNA1509_22236} {RNA1310_84275, RNA1509_22236} {RNA1509_22236, RNA815_43046}
14. MligTC455_20953 115 2.4 Mlig455_002904

Neo: -

Age: -

Region-enriched R2: 5.041/0.00953

2.533 - - - 0.719 0.953 0.861 Mlig455_002904 {REF} {Length: 1514} {RNA1310_19276} {RNA815_20827}
15. MligTC455_29408 45 0.94 Mlig455_038322

Neo: -

Age: -

Region-enriched R2: 8.586/0.00762

MB 2.533 - - - 0.778 0.965 0.790 Mlig455_038322 {REF} {Length: 2059} {Pfam: Globin [PF00042.24, score=57.8]} {Human: ENSG00000198125, MB, myoglobin, [RH, Score=47.8, Expect=5e-07]} {Mouse: ENSMUSG00000018893, Mb, myoglobin, [RH, Score=45.4, Expect=2e-06]} {Celegans: WBGene00008996, glb-14, GLoBin related, [Score=51.6, Expect=4e-08]} {Smed: dd_Smed_v6_15997_0_1, dd_Smed_v6_15997_0_1, [RH, Score=63.5, Expect=1e-12]} {RNA1509_48898} {RNA1310_47695} {RNA815_7096.1}
16. MligTC455_41130 1186 24.72 Mlig455_000166, Mlig455_000179, Mlig455_067712

Neo: -

Age: Down-Up-Down

Region-specific R2: 5.626

Region-enriched R2: 4.906/0.00009

Regeneration-downregulated R3: -5.200

Regeneration-depleted R3: -5.200

2.525 - - - 0.770 0.960 0.795

Mlig455_000166 {REF} {Length: 479} {RNA1509_36590} {RNA1310_65705}

Mlig455_000179 {REF} {Length: 479} {RNA1509_36590} {RNA1310_65705}

Mlig455_067712 {REF} {Length: 479} {RNA1509_36590} {RNA1310_65705}
17. MligTC455_43621 222 4.63 Mlig455_025703

Neo: -

Age: -

Region-enriched R4: 4.147/0.00000

2.516 - - - 0.834 0.962 0.720 Mlig455_025703 {REF} {Length: 2480} {RNA1509_50338} {RNA1310_25031} {RNA815_24211}
18. MligTC455_18099 24 0.51 Mlig455_036525

Neo: -

Age: -

PPA1 2.478 - - - 0.701 0.963 0.814 Mlig455_036525 {REF} {Length: 1911} {Pfam: Inorganic pyrophosphatase [PF00719.21, score=181.8]} {Human: ENSG00000180817, PPA1, pyrophosphatase (inorganic) 1, [Score=304, Expect=2e-103]; ENSG00000138777, PPA2, pyrophosphatase (inorganic) 2, [Score=295, Expect=4e-99]} {Mouse: ENSMUSG00000020089, Ppa1, pyrophosphatase (inorganic) 1, [Score=307, Expect=9e-105]} {Dmel: FBgn0016687, Nurf-38, Nucleosome remodeling factor - 38kD, [Score=303, Expect=2e-103]} {Celegans: WBGene00008149, pyp-1, Probable inorganic pyrophosphatase 1, [Score=315, Expect=5e-108]} {Smed: dd_Smed_v6_625_0_1, dd_Smed_v6_625_0_1, [Score=290, Expect=2e-98]} {RNA1310_57333.1} {RNA815_22340}
19. MligTC455_43315 118 2.46 Mlig455_022312, Mlig455_069884

Neo: -

Age: logFC(26M/2M)=0.730

KREMEN2 2.468 - - 0.963 0.701 - 0.804

Mlig455_022312 {REF} {Length: 2816} {Pfam: WSC domain [PF01822.21, score=54.1]} {Human: ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=52.0, Expect=2e-07]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=50.1, Expect=5e-07]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=63.9, Expect=1e-11]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=47.4, Expect=3e-06]} {RNA1509_40165} {RNA1310_40900} {RNA815_15848}

Mlig455_069884 {REF} {Length: 2143} {Pfam: WSC domain [PF01822.21, score=54.1]} {Human: ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=52.0, Expect=2e-07]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=50.1, Expect=5e-07]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=63.9, Expect=1e-11]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=47.4, Expect=3e-06]} {RNA1509_40165} {RNA1310_40900} {RNA815_15848}
20. MligTC455_29584 197 4.11 Mlig455_014733

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.711

2.427 - - 0.958 - 0.729 0.740 Mlig455_014733 {REF} {Length: 2216} {Smed: dd_Smed_v6_9995_0_1, dd_Smed_v6_9995_0_1, [RH, Score=90.5, Expect=2e-20]} {RNA1509_17870} {RNA1310_2913} {RNA815_5700}
21. MligTC455_22666 105 2.19 Mlig455_030337, Mlig455_034130

Neo: -

Age: -

GPR139, SSTR5 1.916 - - - - 0.964 0.952

Mlig455_030337 {REF} {Length: 1261} {Pfam: Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=56.5]; 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=48.4]} {Human: ENSG00000162009, SSTR5, somatostatin receptor 5, [Score=50.8, Expect=3e-06]; ENSG00000180269, GPR139, G protein-coupled receptor 139, [Score=48.5, Expect=1e-05]} {Mouse: ENSMUSG00000037014, Sstr4, somatostatin receptor 4, [Score=52.0, Expect=8e-07]} {Dmel: FBgn0029768, SPR, Sex peptide receptor, [Score=49.7, Expect=3e-06]} {Celegans: WBGene00020586, frpr-18, FLP-2 receptor; FMRFamide Peptide Receptor family, [Score=73.9, Expect=3e-14]} {Smed: dd_Smed_v6_21549_0_1, dd_Smed_v6_21549_0_1, [RH, Score=203, Expect=1e-61]} {RNA1310_22133.1} {RNA815_47608}

Mlig455_034130 {REF} {Length: 1976} {Pfam: Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=55.5]; 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=47.0]} {Human: ENSG00000180269, GPR139, G protein-coupled receptor 139, [Score=50.8, Expect=3e-06]; ENSG00000162009, SSTR5, somatostatin receptor 5, [Score=50.1, Expect=4e-06]} {Mouse: ENSMUSG00000037014, Sstr4, somatostatin receptor 4, [Score=52.4, Expect=7e-07]} {Dmel: FBgn0029768, SPR, Sex peptide receptor, [Score=50.4, Expect=2e-06]} {Celegans: WBGene00020586, frpr-18, FLP-2 receptor; FMRFamide Peptide Receptor family, [Score=73.9, Expect=4e-14]} {Smed: dd_Smed_v6_21549_0_1, dd_Smed_v6_21549_0_1, [RH, Score=200, Expect=4e-60]} {RNA1310_22133.1} {RNA815_39922}
22. MligTC455_39214 65 1.35 Mlig455_027340, Mlig455_027348

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.560

OMD 1.904 - - - - 0.936 0.968

Mlig455_027340 {REF} {Length: 3401} {Pfam: Leucine Rich repeats (2 copies) [PF12799.9, score=58.5]; Leucine rich repeat [PF13855.8, score=53.3]; TMEM154 protein family [PF15102.8, score=23.0]; Leucine rich repeat N-terminal domain [PF01462.20, score=22.2]; Wnt and FGF inhibitory regulator [PF13908.8, score=21.3]; Ephrin type-A receptor 2 transmembrane domain [PF14575.8, score=19.3]} {Mouse: ENSMUSG00000031558, Slit2, slit guidance ligand 2, [Score=52.8, Expect=2e-06]} {RNA1509_36831} {RNA1310_6539.2, RNA1509_36831} {RNA1509_36831, RNA815_7072}

Mlig455_027348 {REF} {Length: 1269} {Pfam: Leucine rich repeat [PF13855.8, score=51.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=50.0]} {Human: ENSG00000127083, OMD, osteomodulin, [Score=48.5, Expect=9e-06]} {RNA1509_36831} {RNA1310_26634} {RNA815_7072}
23. MligTC455_23752 138 2.87 Mlig455_056854

Neo: -

Age: Up-Down-Down

GRIK3 1.899 - - - - 0.947 0.952 Mlig455_056854 {REF} {Length: 4616} {Pfam: Ligand-gated ion channel [PF00060.28, score=110.6]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=92.2]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=86.6]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=222, Expect=9e-60]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=219, Expect=6e-59]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=218, Expect=9e-59]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=217, Expect=4e-58]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=215, Expect=2e-57]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=214, Expect=3e-57]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=212, Expect=3e-56]; ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=212, Expect=4e-56]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=211, Expect=6e-56]; ENSG00000105737, GRIK5, glutamate ionotropic receptor kainate type subunit 5, [Score=211, Expect=6e-56]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=223, Expect=5e-60]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=220, Expect=4e-59]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=217, Expect=2e-58]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=216, Expect=6e-58]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=216, Expect=6e-58]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=214, Expect=4e-57]; ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=214, Expect=5e-57]} {Dmel: FBgn0031634, Ir25a, Ionotropic receptor 25a, [RH, Score=294, Expect=8e-85]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [RH, Score=320, Expect=6e-95]} {Smed: dd_Smed_v6_16476_0_1, dd_Smed_v6_16476_0_1, [RH, Score=658, Expect=0.0]} {RNA1509_25374} {RNA1310_4098, RNA1509_25374} {RNA1509_25374, RNA815_19029}
24. MligTC455_09595 48 1.01 Mlig455_030009

Neo: -

Age: -

OPRM1 1.891 - - 0.923 - 0.968 - Mlig455_030009 {REF} {Length: 1508} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=44.4]; Serpentine type 7TM GPCR chemoreceptor Sra [PF02117.18, score=19.7]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=19.6]} {Human: ENSG00000112038, OPRM1, opioid receptor mu 1, [Score=56.2, Expect=5e-08]} {Mouse: ENSMUSG00000000766, Oprm1, opioid receptor, mu 1, [Score=54.7, Expect=9e-08]} {Celegans: WBGene00021510, frpr-19, FMRFamide Peptide Receptor family, [Score=47.8, Expect=7e-06]} {RNA1310_43388} {RNA815_47203}
25. MligTC455_14036 33 0.69 Mlig455_059133

Neo: -

Age: -

Region-enriched R2: 6.942/0.00135

GRIK2 1.877 - 0.907 - - 0.970 - Mlig455_059133 {REF} {Length: 360} {TRANSSPLICED} {Pfam: Ligand-gated ion channel [PF00060.28, score=91.4]; Receptor family ligand binding region [PF01094.30, score=55.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=50.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=31.2]; Iron-containing alcohol dehydrogenase [PF13685.8, score=21.6]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=167, Expect=5e-42]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=166, Expect=8e-42]} {Dmel: FBgn0038837, CG3822, [Score=171, Expect=1e-43]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=129, Expect=1e-30]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [RH, Score=273, Expect=6e-84]}
26. MligTC455_40125 953 19.86 Mlig455_005600, Mlig455_014458

Neo: -

Age: Up-Down-Down

KIF13B, KIF1B 1.877 - - - - 0.917 0.960

Mlig455_005600 {REF} {Length: 4684} {Pfam: Kinesin protein 1B [PF12423.10, score=42.5]} {Human: ENSG00000197892, KIF13B, kinesin family member 13B, [Score=61.6, Expect=2e-09]} {Mouse: ENSMUSG00000087236, Kif28, kinesin family member 28, [Score=98.2, Expect=4e-21]} {Dmel: FBgn0019968, Khc-73, Kinesin heavy chain 73, [Score=57.0, Expect=3e-08]} {Celegans: WBGene00002218, klp-6, Kinesin-like protein, [Score=177, Expect=5e-48]} {Smed: dd_Smed_v6_20223_0_1, dd_Smed_v6_20223_0_1, [Score=118, Expect=3e-28]} {RNA1509_6760} {RNA1310_2628} {RNA815_4402}

Mlig455_014458 {REF} {Length: 3819} {Pfam: Kinesin motor domain [PF00225.25, score=336.4]; Microtubule binding [PF16796.7, score=68.9]; Kinesin protein 1B [PF12423.10, score=40.0]; Kinesin-associated [PF16183.7, score=27.3]} {Human: ENSG00000054523, KIF1B, kinesin family member 1B, [Score=404, Expect=2e-123]; ENSG00000137177, KIF13A, kinesin family member 13A, [Score=404, Expect=9e-120]; ENSG00000130294, KIF1A, kinesin family member 1A, [Score=404, Expect=2e-120]; ENSG00000197892, KIF13B, kinesin family member 13B, [Score=399, Expect=2e-125]; ENSG00000129250, KIF1C, kinesin family member 1C, [Score=398, Expect=2e-121]} {Mouse: ENSMUSG00000087236, Kif28, kinesin family member 28, [Score=568, Expect=0.0]} {Dmel: FBgn0019968, Khc-73, Kinesin heavy chain 73, [Score=415, Expect=5e-124]} {Celegans: WBGene00002218, klp-6, Kinesin-like protein, [RH, Score=818, Expect=0.0]} {Smed: dd_Smed_v6_12573_0_1, dd_Smed_v6_12573_0_1, [Score=617, Expect=0.0]} {RNA1509_6760} {RNA1310_1667.1} {RNA815_1144}
27. MligTC455_47525 119 2.49 Mlig455_030977

Neo: -

Age: Down-Up-Up

Region-enriched R2: 3.232/0.02097

CALM2 1.845 - - - 0.886 - 0.959 Mlig455_030977 {REF} {Length: 1161} {Pfam: EF hand [PF00036.34, score=76.5]; EF-hand domain pair [PF13499.8, score=73.7]; EF-hand domain [PF13405.8, score=66.7]; EF-hand domain [PF14658.8, score=42.2]; EF hand [PF13202.8, score=35.1]; EF-hand domain pair [PF13833.8, score=33.7]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=30.9]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=151, Expect=4e-47]; ENSG00000198668, CALM1, calmodulin 1, [Score=151, Expect=4e-47]; ENSG00000160014, CALM3, calmodulin 3, [Score=151, Expect=4e-47]} {Mouse: ENSMUSG00000036438, Calm2, calmodulin 2, [Score=151, Expect=3e-47]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=151, Expect=3e-47]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=151, Expect=3e-47]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=152, Expect=8e-48]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=151, Expect=1e-47]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=151, Expect=1e-47]} {RNA1310_31633} {RNA815_34040}
28. MligTC455_20237 371 7.72 Mlig455_042388

Neo: -

Age: -

1.838 - - 0.971 - - 0.867 Mlig455_042388 {REF} {Length: 3463} {RNA1509_32804} {RNA1310_15777} {RNA815_23756}
29. MligTC455_51288 32 0.66 Mlig455_033307

Neo: -

Age: -

NRG2 1.836 - - - - 0.980 0.856 Mlig455_033307 {REF} {Length: 1876} {TRANSSPLICED} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=62.6]; Immunoglobulin domain [PF13927.8, score=57.8]; Immunoglobulin domain [PF00047.27, score=52.9]; Immunoglobulin domain [PF13895.8, score=42.7]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=21.9]; Immunoglobulin V-set domain [PF07686.19, score=21.5]} {Human: ENSG00000158458, NRG2, neuregulin 2, [RH, Score=78.6, Expect=9e-15]} {Mouse: ENSMUSG00000060275, Nrg2, neuregulin 2, [Score=79.3, Expect=5e-15]} {Dmel: FBgn0003984, vn, vein, [RH, Score=79.3, Expect=3e-15]} {Celegans: WBGene00001863, him-4, Hemicentin; High Incidence of Males (Increased X chromosome loss), [Score=58.5, Expect=1e-08]} {Smed: dd_Smed_v6_16809_0_1, dd_Smed_v6_16809_0_1, [RH, Score=77.8, Expect=3e-15]} {RNA1310_26045.2} {RNA815_30218}
30. MligTC455_47420 218 4.54 Mlig455_017159, Mlig455_048110

Neo: -

Age: -

Region-specific R2: 6.469

Region-enriched R2: 5.851/0.00135

1.831 - - - - 0.967 0.864

Mlig455_017159 {REF} {Length: 1062} {RNA1509_35349} {RNA1310_81586}

Mlig455_048110 {REF} {Length: 527} {RNA1310_81586}
31. MligTC455_24301 172 3.57 Mlig455_029246

Neo: -

Age: -

KCNQ5 1.83 - - - - 0.957 0.873 Mlig455_029246 {REF} {Length: 3519} {Pfam: KCNQ voltage-gated potassium channel [PF03520.16, score=122.6]; Ion transport protein [PF00520.33, score=99.3]; Ion channel [PF07885.18, score=51.1]; Putative sensor [PF13796.8, score=18.6]} {Human: ENSG00000185760, KCNQ5, potassium voltage-gated channel subfamily Q member 5, [RH, Score=477, Expect=9e-155]; ENSG00000117013, KCNQ4, potassium voltage-gated channel subfamily Q member 4, [RH, Score=459, Expect=3e-151]} {Mouse: ENSMUSG00000028033, Kcnq5, potassium voltage-gated channel, subfamily Q, member 5, [RH, Score=476, Expect=1e-154]} {Dmel: FBgn0033494, KCNQ, KCNQ potassium channel, [RH, Score=603, Expect=0.0]} {Celegans: WBGene00002233, kqt-1, KQT-1 potassium channel; Potassium channel, KvQLT family, [RH, Score=524, Expect=4e-176]} {Smed: dd_Smed_v6_12681_0_1, dd_Smed_v6_12681_0_1, [RH, Score=639, Expect=0.0]} {RNA1509_34272} {RNA1310_3730.1, RNA1509_34272} {RNA1509_34272, RNA815_2787}
32. MligTC455_43557 362 7.55 Mlig455_059172, Mlig455_065527

Neo: -

Age: Down-Down-Up

Region-specific R2: 6.284

Region-enriched R2: 5.832/0.00001

ANKRD63 1.828 - - - - 0.954 0.874

Mlig455_059172 {REF} {Length: 1739} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=53.2]; Ankyrin repeats (many copies) [PF13637.8, score=42.6]; Ankyrin repeat [PF13606.8, score=27.6]; Ankyrin repeats (many copies) [PF13857.8, score=27.1]; Ankyrin repeat [PF00023.32, score=25.9]} {Human: ENSG00000230778, ANKRD63, ankyrin repeat domain 63, [Score=68.2, Expect=7e-12]} {Mouse: ENSMUSG00000078137, Ankrd63, ankyrin repeat domain 63, [Score=67.4, Expect=7e-12]} {Dmel: FBgn0043884, mask, multiple ankyrin repeats single KH domain, [Score=49.3, Expect=7e-06]} {Celegans: WBGene00011240, R11A8.7, Ankyrin repeat and KH domain-containing protein R11A8.7, [Score=49.3, Expect=4e-06]} {Smed: dd_Smed_v6_10280_0_1, dd_Smed_v6_10280_0_1, [Score=81.3, Expect=1e-16]} {RNA1310_44826} {RNA815_62096}

Mlig455_065527 {REF} {Length: 2998} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=52.3]; Ankyrin repeats (many copies) [PF13637.8, score=42.0]; Ankyrin repeats (many copies) [PF13857.8, score=26.7]; Ankyrin repeat [PF00023.32, score=26.0]; Ankyrin repeat [PF13606.8, score=22.6]} {Human: ENSG00000230778, ANKRD63, ankyrin repeat domain 63, [Score=68.2, Expect=7e-12]} {Mouse: ENSMUSG00000078137, Ankrd63, ankyrin repeat domain 63, [Score=68.2, Expect=6e-12]} {Dmel: FBgn0043884, mask, multiple ankyrin repeats single KH domain, [Score=50.1, Expect=5e-06]} {Celegans: WBGene00011240, R11A8.7, Ankyrin repeat and KH domain-containing protein R11A8.7, [Score=50.4, Expect=2e-06]} {Smed: dd_Smed_v6_10280_0_1, dd_Smed_v6_10280_0_1, [Score=80.9, Expect=2e-16]} {RNA1509_30872} {RNA1310_44826} {RNA815_62096}
33. MligTC455_52081 79 1.64 Mlig455_025698, Mlig455_025723

Neo: -

Age: -

Region-enriched R8: 4.583/0.03342

SLC22A3 1.827 - - - - 0.969 0.858

Mlig455_025698 {REF} {Length: 2167} {Pfam: Sugar (and other) transporter [PF00083.26, score=88.1]; Major Facilitator Superfamily [PF07690.18, score=58.6]} {Human: ENSG00000146477, SLC22A3, solute carrier family 22 member 3, [Score=203, Expect=3e-57]; ENSG00000112499, SLC22A2, solute carrier family 22 member 2, [Score=199, Expect=1e-55]; ENSG00000197375, SLC22A5, solute carrier family 22 member 5, [Score=194, Expect=5e-54]; ENSG00000197901, SLC22A6, solute carrier family 22 member 6, [Score=193, Expect=1e-53]} {Mouse: ENSMUSG00000023828, Slc22a3, solute carrier family 22 (organic cation transporter), member 3, [Score=199, Expect=5e-56]; ENSMUSG00000040966, Slc22a2, solute carrier family 22 (organic cation transporter), member 2, [Score=196, Expect=6e-55]; ENSMUSG00000023829, Slc22a1, solute carrier family 22 (organic cation transporter), member 1, [Score=194, Expect=4e-54]; ENSMUSG00000063652, Slc22a21, solute carrier family 22 (organic cation transporter), member 21, [Score=192, Expect=2e-53]; ENSMUSG00000024650, Slc22a6, solute carrier family 22 (organic anion transporter), member 6, [Score=191, Expect=3e-53]} {Dmel: FBgn0019952, Orct, Organic cation transporter, [Score=204, Expect=4e-58]} {Celegans: WBGene00022348, Y82E9BR.16, [Score=159, Expect=1e-41]} {Smed: dd_Smed_v6_10903_0_1, dd_Smed_v6_10903_0_1, [Score=186, Expect=7e-52]} {RNA1310_48310} {RNA815_24964}

Mlig455_025723 {REF} {Length: 199} {NoTransDecoderORF}
34. MligTC455_11559 259 5.4 Mlig455_058274, Mlig455_070792

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.973

Region-enriched R2: 6.488/0.00000

1.826 - - 0.856 - 0.970 -

Mlig455_058274 {REF} {Length: 786} {RNA1509_58923} {RNA1310_41706} {RNA815_20876}

Mlig455_070792 {REF} {Length: 891} {RNA1509_58923} {RNA1310_41706} {RNA815_20876}
35. MligTC455_31663 23 0.48 Mlig455_013845

Neo: -

Age: -

1.825 - - - - 0.963 0.862 Mlig455_013845 {REF} {Length: 1056} {RNA1310_32319} {RNA815_18072}
36. MligTC455_28711 44 0.91 Mlig455_022368, Mlig455_022378, Mlig455_022455

Neo: -

Age: -

KREMEN2 1.819 - - - - 0.951 0.868

Mlig455_022368 {REF} {Length: 1557} {Pfam: WSC domain [PF01822.21, score=45.5]; PAN domain [PF00024.28, score=22.6]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=46.2, Expect=1e-05]} {RNA1310_35396.1} {RNA815_23500}

Mlig455_022378 {REF} {Length: 1444} {Pfam: WSC domain [PF01822.21, score=37.3]; PAN domain [PF00024.28, score=21.3]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=48.1, Expect=1e-05]} {RNA1310_89673} {RNA815_59435}

Mlig455_022455 {REF} {Length: 1345} {Pfam: WSC domain [PF01822.21, score=51.4]; PAN domain [PF00024.28, score=23.1]} {Human: ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=52.4, Expect=2e-07]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=50.4, Expect=7e-07]} {RNA1310_89673} {RNA815_23500}
37. MligTC455_13902 400 8.32 Mlig455_011022, Mlig455_011835, Mlig455_013117

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.562

Region-specific R2: 6.064

Region-enriched R2: 5.080/0.00072

1.811 - - - - 0.951 0.860

Mlig455_011022 {REF} {Length: 631} {RNA1509_28527} {RNA1310_38436.1} {RNA815_28856}

Mlig455_011835 {REF} {Length: 2387} {RNA1509_28527} {RNA1310_38436.1} {RNA815_28856}

Mlig455_013117 {REF} {Length: 1663} {NoTransDecoderORF} {RNA1310_40518} {RNA815_20411.2}
38. MligTC455_26091 161 3.36 Mlig455_047190

Neo: -

Age: -

Region-enriched R2: 4.521/0.00020

1.81 - - - - 0.960 0.850 Mlig455_047190 {REF} {Length: 2450} {Pfam: Lectin C-type domain [PF00059.23, score=23.6]} {RNA1509_2912} {RNA1310_27113} {RNA815_24719}
39. MligTC455_31163 72 1.51 Mlig455_045625

Neo: -

Age: Up-Down-Down

1.802 - - - - 0.963 0.839 Mlig455_045625 {REF} {Length: 1957} {RNA1509_21720} {RNA1310_14760, RNA1509_21720} {RNA1509_21720, RNA815_24583}
40. MligTC455_50626 1034 21.55 Mlig455_039925, Mlig455_041197, Mlig455_070097

Neo: -

Age: -

ANKRD53 1.8 - - 0.955 - - 0.845

Mlig455_039925 {REF} {Length: 2156} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=73.7]; Ankyrin repeats (3 copies) [PF12796.9, score=62.9]; Ankyrin repeats (many copies) [PF13857.8, score=40.4]; Ankyrin repeat [PF13606.8, score=34.4]; Ankyrin repeat [PF00023.32, score=30.0]} {Human: ENSG00000144031, ANKRD53, ankyrin repeat domain 53, [RH, Score=141, Expect=7e-36]} {Mouse: ENSMUSG00000014747, Ankrd53, ankyrin repeat domain 53, [RH, Score=127, Expect=4e-31]} {Dmel: FBgn0262111, f, forked, [Score=66.6, Expect=4e-11]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=67.4, Expect=2e-11]} {Smed: dd_Smed_v6_13629_0_1, dd_Smed_v6_13629_0_1, [RH, Score=262, Expect=4e-82]} {RNA1509_10948} {RNA1310_11710, RNA1509_10948} {RNA1509_10948, RNA815_4206}

Mlig455_041197 {REF} {Length: 2183} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=73.7]; Ankyrin repeats (3 copies) [PF12796.9, score=62.9]; Ankyrin repeats (many copies) [PF13857.8, score=40.5]; Ankyrin repeat [PF13606.8, score=34.4]; Ankyrin repeat [PF00023.32, score=30.0]} {Human: ENSG00000144031, ANKRD53, ankyrin repeat domain 53, [RH, Score=142, Expect=7e-36]} {Mouse: ENSMUSG00000014747, Ankrd53, ankyrin repeat domain 53, [RH, Score=127, Expect=4e-31]} {Dmel: FBgn0262111, f, forked, [Score=66.2, Expect=4e-11]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=67.0, Expect=3e-11]} {Smed: dd_Smed_v6_13629_0_1, dd_Smed_v6_13629_0_1, [RH, Score=261, Expect=7e-82]} {RNA1509_10948} {RNA1310_11710} {RNA815_4206}

Mlig455_070097 {REF} {Length: 2181} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=71.5]; Ankyrin repeats (3 copies) [PF12796.9, score=62.6]; Ankyrin repeats (many copies) [PF13857.8, score=39.1]; Ankyrin repeat [PF13606.8, score=34.3]; Ankyrin repeat [PF00023.32, score=29.6]} {Human: ENSG00000144031, ANKRD53, ankyrin repeat domain 53, [RH, Score=140, Expect=1e-35]} {Mouse: ENSMUSG00000014747, Ankrd53, ankyrin repeat domain 53, [RH, Score=128, Expect=2e-31]} {Dmel: FBgn0262111, f, forked, [Score=65.9, Expect=6e-11]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=76.6, Expect=3e-14]} {Smed: dd_Smed_v6_13629_0_1, dd_Smed_v6_13629_0_1, [RH, Score=259, Expect=4e-81]} {RNA1509_10948} {RNA1310_11710} {RNA815_4206}
41. MligTC455_13493 28 0.58 Mlig455_020299

Neo: -

Age: -

1.795 - - - 0.816 0.979 - Mlig455_020299 {REF} {Length: 568} {RNA1310_11315} {RNA815_53929}
42. MligTC455_14872 28 0.58 Mlig455_064004, Mlig455_064044

Neo: -

Age: logFC(26M/2M)=1.526

CLCA1 1.795 - - - - 0.963 0.832

Mlig455_064004 {REF} {Length: 4380} {Pfam: von Willebrand factor type A domain [PF00092.30, score=55.0]; von Willebrand factor type A domain [PF13768.8, score=48.2]; von Willebrand factor type A domain [PF13519.8, score=47.8]; vWA found in TerF C terminus [PF10138.11, score=29.1]; VWA domain containing CoxE-like protein [PF05762.16, score=28.0]; Calcium-activated chloride channel N terminal [PF08434.13, score=19.9]} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [Score=150, Expect=1e-36]} {Mouse: ENSMUSG00000028255, Clca1, chloride channel accessory 1, [Score=154, Expect=6e-38]} {Smed: dd_Smed_v6_968_0_1, dd_Smed_v6_968_0_1, [Score=89.0, Expect=6e-18]} {RNA1509_43698} {RNA1310_4397} {RNA815_4081}

Mlig455_064044 {REF} {Length: 4389} {Pfam: von Willebrand factor type A domain [PF00092.30, score=57.6]; von Willebrand factor type A domain [PF13768.8, score=50.7]; von Willebrand factor type A domain [PF13519.8, score=47.7]; vWA found in TerF C terminus [PF10138.11, score=29.0]; VWA domain containing CoxE-like protein [PF05762.16, score=26.0]; Calcium-activated chloride channel N terminal [PF08434.13, score=24.0]} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [Score=157, Expect=9e-39]} {Mouse: ENSMUSG00000028255, Clca1, chloride channel accessory 1, [Score=159, Expect=2e-39]} {Smed: dd_Smed_v6_968_0_1, dd_Smed_v6_968_0_1, [Score=91.3, Expect=1e-18]} {RNA1509_43698} {RNA1310_4397, RNA1509_43698} {RNA1509_43698, RNA815_4081}
43. MligTC455_17902 217 4.51 Mlig455_058516, Mlig455_058526

Neo: -

Age: -

AC012184.2, DDX25 1.793 - - - - 0.965 0.828

Mlig455_058516 {REF} {Length: 3640} {TRANSSPLICED} {Pfam: DEAD/DEAH box helicase [PF00270.31, score=97.6]; Helicase conserved C-terminal domain [PF00271.33, score=82.7]} {Human: ENSG00000260537, AC012184.2, novel protein, DDX19B and DDX19A readthrough, [RH, Score=436, Expect=3e-142]; ENSG00000168872, DDX19A, DEAD-box helicase 19A, [RH, Score=436, Expect=5e-142]; ENSG00000157349, DDX19B, DEAD-box helicase 19B, [RH, Score=434, Expect=4e-141]} {Mouse: ENSMUSG00000015023, Ddx19a, DEAD (Asp-Glu-Ala-Asp) box polypeptide 19a, [RH, Score=428, Expect=3e-139]; ENSMUSG00000033658, Ddx19b, DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b, [RH, Score=424, Expect=1e-137]} {Dmel: FBgn0024804, Dbp80, Dead box protein 80, [RH, Score=393, Expect=1e-126]} {Celegans: WBGene00011580, ddx-19, DEAD boX helicase homolog, [RH, Score=358, Expect=7e-107]} {Smed: dd_Smed_v6_4165_0_1, dd_Smed_v6_4165_0_1, [RH, Score=359, Expect=5e-113]} {RNA1509_14725} {RNA1310_12283, RNA1509_14725} {RNA1509_14725, RNA815_5747}

Mlig455_058526 {REF} {Length: 2588} {Pfam: Helicase conserved C-terminal domain [PF00271.33, score=79.3]} {Human: ENSG00000109832, DDX25, DEAD-box helicase 25, [Score=143, Expect=3e-36]; ENSG00000157349, DDX19B, DEAD-box helicase 19B, [Score=139, Expect=1e-34]; ENSG00000168872, DDX19A, DEAD-box helicase 19A, [Score=139, Expect=2e-34]; ENSG00000260537, AC012184.2, novel protein, DDX19B and DDX19A readthrough, [Score=139, Expect=2e-34]} {Mouse: ENSMUSG00000032101, Ddx25, DEAD (Asp-Glu-Ala-Asp) box polypeptide 25, [Score=142, Expect=2e-35]; ENSMUSG00000033658, Ddx19b, DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b, [Score=139, Expect=1e-34]; ENSMUSG00000015023, Ddx19a, DEAD (Asp-Glu-Ala-Asp) box polypeptide 19a, [Score=139, Expect=1e-34]} {Dmel: FBgn0037573, CG7483, [Score=117, Expect=6e-28]} {Celegans: WBGene00002083, inf-1, Eukaryotic initiation factor 4A, [Score=127, Expect=3e-31]} {Smed: dd_Smed_v6_4165_0_1, dd_Smed_v6_4165_0_1, [Score=135, Expect=2e-33]} {RNA1509_14725} {RNA1310_12283} {RNA815_17365}
44. MligTC455_18100 17 0.36 Mlig455_069127

Neo: -

Age: -

PPA1 1.79 - - - - 0.964 0.826 Mlig455_069127 {REF} {Length: 2015} {Pfam: Inorganic pyrophosphatase [PF00719.21, score=181.8]} {Human: ENSG00000180817, PPA1, pyrophosphatase (inorganic) 1, [Score=304, Expect=2e-103]; ENSG00000138777, PPA2, pyrophosphatase (inorganic) 2, [Score=295, Expect=4e-99]} {Mouse: ENSMUSG00000020089, Ppa1, pyrophosphatase (inorganic) 1, [Score=307, Expect=9e-105]} {Dmel: FBgn0016687, Nurf-38, Nucleosome remodeling factor - 38kD, [Score=303, Expect=2e-103]} {Celegans: WBGene00008149, pyp-1, Probable inorganic pyrophosphatase 1, [Score=315, Expect=5e-108]} {Smed: dd_Smed_v6_625_0_1, dd_Smed_v6_625_0_1, [Score=290, Expect=2e-98]} {RNA1509_39915} {RNA1310_57333.1} {RNA815_22340}
45. MligTC455_18003 26 0.54 Mlig455_050296

Neo: -

Age: -

1.783 - - - - 0.956 0.827 Mlig455_050296 {REF} {Length: 1873} {RNA1509_36362} {RNA1310_57811} {RNA815_23362}
46. MligTC455_07614 39 0.81 Mlig455_022829, Mlig455_022910, Mlig455_022919

Neo: -

Age: Up-Down-Down

1.782 - 0.821 - - 0.961 -

Mlig455_022829 {REF} {Length: 304} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_46811} {RNA1310_886.2} {RNA815_1557}

Mlig455_022910 {REF} {Length: 230} {NoTransDecoderORF} {RNA1509_46811} {RNA1310_886.2} {RNA815_1557}

Mlig455_022919 {REF} {Length: 318} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_46811} {RNA1310_886.2} {RNA815_1557}
47. MligTC455_12446 8 0.17 Mlig455_018624, Mlig455_018810

Neo: -

Age: -

CHRNA10, CHRNA7 1.78 - - - - 0.961 0.819

Mlig455_018624 {REF} {Length: 3606} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=120.6]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=112.9]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=72.0]} {Human: ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=143, Expect=2e-35]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=142, Expect=2e-35]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=140, Expect=1e-34]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=140, Expect=1e-34]; ENSG00000166736, HTR3A, 5-hydroxytryptamine receptor 3A, [Score=136, Expect=2e-33]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=145, Expect=2e-36]; ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=141, Expect=3e-35]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=140, Expect=2e-35]; ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=139, Expect=2e-34]} {Dmel: FBgn0028875, nAChRalpha5, nicotinic Acetylcholine Receptor alpha5, [Score=142, Expect=2e-34]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=144, Expect=3e-36]} {Smed: dd_Smed_v6_18184_0_1, dd_Smed_v6_18184_0_1, [Score=138, Expect=2e-34]} {RNA1509_9118} {RNA1310_65904} {RNA815_40596}

Mlig455_018810 {REF} {Length: 2717} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=120.6]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=112.8]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=72.2]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=141, Expect=2e-35]; ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=140, Expect=2e-34]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=139, Expect=2e-34]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=139, Expect=2e-34]; ENSG00000166736, HTR3A, 5-hydroxytryptamine receptor 3A, [Score=138, Expect=4e-34]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=145, Expect=2e-36]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=141, Expect=2e-35]; ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=140, Expect=8e-35]; ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=140, Expect=7e-35]} {Dmel: FBgn0028875, nAChRalpha5, nicotinic Acetylcholine Receptor alpha5, [Score=142, Expect=1e-34]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=144, Expect=4e-36]} {Smed: dd_Smed_v6_8058_0_1, dd_Smed_v6_8058_0_1, [Score=139, Expect=1e-34]} {RNA1509_9118} {RNA1310_84333} {RNA815_40596}
48. MligTC455_20149 191 3.98 Mlig455_000246, Mlig455_058518

Neo: -

Age: -

Region-enriched R2: 4.445/0.03524

HPCAL4, NCALD 1.78 - - - - 0.950 0.830

Mlig455_000246 {REF} {Length: 978} {Human: ENSG00000116983, HPCAL4, hippocalcin like 4, [Score=79.0, Expect=2e-17]; ENSG00000104490, NCALD, neurocalcin delta, [Score=79.0, Expect=2e-17]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=77.8, Expect=5e-17]; ENSG00000185774, KCNIP4, potassium voltage-gated channel interacting protein 4, [Score=75.5, Expect=1e-15]} {Mouse: ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=79.0, Expect=1e-17]; ENSMUSG00000046093, Hpcal4, hippocalcin-like 4, [Score=79.0, Expect=1e-17]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=77.0, Expect=7e-17]; ENSMUSG00000029088, Kcnip4, Kv channel interacting protein 4, [Score=75.5, Expect=8e-16]} {Dmel: FBgn0013303, Nca, Neurocalcin, [Score=83.2, Expect=3e-19]} {Celegans: WBGene00003563, ncs-1, Neuronal calcium sensor 1, [Score=67.8, Expect=1e-13]} {Smed: dd_Smed_v6_2568_0_1, dd_Smed_v6_2568_0_1, [Score=72.0, Expect=2e-15]} {RNA1310_101382}

Mlig455_058518 {REF} {Length: 1176} {Human: ENSG00000104490, NCALD, neurocalcin delta, [Score=82.0, Expect=2e-18]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=81.3, Expect=3e-18]; ENSG00000116983, HPCAL4, hippocalcin like 4, [Score=80.1, Expect=7e-18]} {Mouse: ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=82.0, Expect=8e-19]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=80.5, Expect=4e-18]; ENSMUSG00000046093, Hpcal4, hippocalcin-like 4, [Score=80.1, Expect=5e-18]} {Dmel: FBgn0013303, Nca, Neurocalcin, [Score=84.0, Expect=1e-19]} {Celegans: WBGene00003563, ncs-1, Neuronal calcium sensor 1, [Score=67.0, Expect=2e-13]} {Smed: dd_Smed_v6_2568_0_1, dd_Smed_v6_2568_0_1, [Score=73.2, Expect=8e-16]} {RNA1310_101382}
49. MligTC455_14842 21 0.45 Mlig455_041074

Neo: -

Age: -

1.778 - - - - 0.970 0.808 Mlig455_041074 {REF} {Length: 1383} {RNA1310_60383} {RNA815_48502}
50. MligTC455_45811 216 4.5 Mlig455_015628

Neo: -

Age: Down-Up-Down

Region-enriched R2: 5.807/0.00004

1.776 - - - - 0.964 0.812 Mlig455_015628 {REF} {Length: 1061} {RNA1310_43338} {RNA815_24238}
51. MligTC455_18748 104 2.17 Mlig455_024985, Mlig455_024999

Neo: -

Age: -

Region-enriched R2: 6.002/0.00016
Region-enriched R4: 3.433/0.02745

GRIK4 1.774 - - - - 0.978 0.796

Mlig455_024985 {REF} {Length: 1514} {Pfam: Ligand-gated ion channel [PF00060.28, score=76.7]; Receptor family ligand binding region [PF01094.30, score=31.5]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=20.6]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=122, Expect=1e-27]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=124, Expect=1e-28]} {Dmel: FBgn0038837, CG3822, [Score=120, Expect=1e-27]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=99.0, Expect=5e-21]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=196, Expect=2e-55]} {RNA1509_35538} {RNA1310_47299} {RNA815_38321}

Mlig455_024999 {REF} {Length: 3567} {Pfam: Ligand-gated ion channel [PF00060.28, score=76.7]; Receptor family ligand binding region [PF01094.30, score=31.5]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=20.6]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=122, Expect=1e-27]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=124, Expect=1e-28]} {Dmel: FBgn0038837, CG3822, [Score=120, Expect=1e-27]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=99.0, Expect=5e-21]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=196, Expect=2e-55]} {RNA1509_35538} {RNA1310_7578, RNA1509_35538} {RNA1509_35538, RNA815_4987}
52. MligTC455_50777 40 0.83 Mlig455_042072

Neo: -

Age: -

MTNR1B 1.773 - - - - 0.963 0.810 Mlig455_042072 {REF} {Length: 2881} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=78.0]; Olfactory receptor [PF13853.8, score=24.3]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=22.0]} {Human: ENSG00000134640, MTNR1B, melatonin receptor 1B, [Score=94.4, Expect=2e-21]; ENSG00000168412, MTNR1A, melatonin receptor 1A, [Score=90.1, Expect=5e-20]} {Mouse: ENSMUSG00000050901, Mtnr1b, melatonin receptor 1B, [Score=94.0, Expect=2e-21]; ENSMUSG00000054764, Mtnr1a, melatonin receptor 1A, [Score=89.4, Expect=6e-20]} {Dmel: FBgn0004514, Oct-TyrR, Octopamine-Tyramine receptor, [Score=57.0, Expect=7e-09]} {Celegans: WBGene00006428, tkr-3, TachyKinin Receptor family, [Score=52.0, Expect=2e-07]} {Smed: dd_Smed_v6_19535_0_1, dd_Smed_v6_19535_0_1, [Score=95.5, Expect=2e-22]} {RNA1310_66047} {RNA815_34066}
53. MligTC455_12180 107 2.23 Mlig455_038554, Mlig455_052202, Mlig455_053449

Neo: -

Age: logFC(26M/2M)=-0.655

Region-enriched R2: 5.717/0.01573

CNGA3 1.771 - - - - 0.950 0.821

Mlig455_038554 {REF} {Length: 2866} {Pfam: C-terminal leucine zipper domain of cyclic nucleotide-gated channels [PF16526.7, score=75.9]; Cyclic nucleotide-binding domain [PF00027.31, score=69.1]; Ion transport protein [PF00520.33, score=68.6]} {Human: ENSG00000144191, CNGA3, cyclic nucleotide gated channel alpha 3, [RH, Score=650, Expect=0.0]} {Mouse: ENSMUSG00000026114, Cnga3, cyclic nucleotide gated channel alpha 3, [RH, Score=644, Expect=0.0]} {Dmel: FBgn0261612, CngA, Cyclic nucleotide-gated ion channel subunit A, [RH, Score=607, Expect=0.0]} {Celegans: WBGene00006526, tax-4, Cyclic nucleotide-gated cation channel, [RH, Score=563, Expect=0.0]} {Smed: dd_Smed_v6_22398_0_1, dd_Smed_v6_22398_0_1, [RH, Score=669, Expect=0.0]} {RNA1310_22950} {RNA815_16119}

Mlig455_052202 {REF} {Length: 3203} {Pfam: C-terminal leucine zipper domain of cyclic nucleotide-gated channels [PF16526.7, score=76.1]; Cyclic nucleotide-binding domain [PF00027.31, score=69.1]; Ion transport protein [PF00520.33, score=68.2]} {Human: ENSG00000144191, CNGA3, cyclic nucleotide gated channel alpha 3, [RH, Score=650, Expect=0.0]} {Mouse: ENSMUSG00000026114, Cnga3, cyclic nucleotide gated channel alpha 3, [RH, Score=644, Expect=0.0]} {Dmel: FBgn0261612, CngA, Cyclic nucleotide-gated ion channel subunit A, [RH, Score=605, Expect=0.0]} {Celegans: WBGene00006526, tax-4, Cyclic nucleotide-gated cation channel, [RH, Score=563, Expect=0.0]} {Smed: dd_Smed_v6_22398_0_1, dd_Smed_v6_22398_0_1, [RH, Score=667, Expect=0.0]} {RNA1310_22950} {RNA815_16119}

Mlig455_053449 {REF} {Length: 991} {Pfam: C-terminal leucine zipper domain of cyclic nucleotide-gated channels [PF16526.7, score=79.9]; Cyclic nucleotide-binding domain [PF00027.31, score=29.1]} {Human: ENSG00000144191, CNGA3, cyclic nucleotide gated channel alpha 3, [Score=171, Expect=7e-50]} {Mouse: ENSMUSG00000026114, Cnga3, cyclic nucleotide gated channel alpha 3, [Score=161, Expect=2e-46]; ENSMUSG00000067220, Cnga1, cyclic nucleotide gated channel alpha 1, [Score=155, Expect=4e-44]} {Dmel: FBgn0261612, CngA, Cyclic nucleotide-gated ion channel subunit A, [Score=148, Expect=1e-41]} {Celegans: WBGene00006526, tax-4, Cyclic nucleotide-gated cation channel, [Score=149, Expect=3e-42]} {Smed: dd_Smed_v6_22398_0_1, dd_Smed_v6_22398_0_1, [Score=155, Expect=8e-45]} {RNA1310_61700} {RNA815_16119}
54. MligTC455_32241 156 3.24 Mlig455_063650

Neo: -

Age: -

Region-enriched R4: 3.105/0.02582

MGLL 1.769 - - - - 0.992 0.777 Mlig455_063650 {REF} {Length: 1932} {Pfam: Serine aminopeptidase, S33 [PF12146.10, score=135.3]; Alpha/beta hydrolase family [PF12697.9, score=39.2]; alpha/beta hydrolase fold [PF00561.22, score=34.4]; Prolyl oligopeptidase family [PF00326.23, score=21.7]} {Human: ENSG00000074416, MGLL, monoglyceride lipase, [Score=97.4, Expect=6e-23]} {Mouse: ENSMUSG00000033174, Mgll, monoglyceride lipase, [Score=106, Expect=2e-26]} {Smed: dd_Smed_v6_6796_0_1, dd_Smed_v6_6796_0_1, [Score=91.7, Expect=2e-21]} {RNA1509_47433} {RNA1310_29208} {RNA815_26468}
55. MligTC455_53524 34 0.7 Mlig455_010882

Neo: -

Age: -

Region-enriched R2: 5.283/0.01696

1.769 - - - - 0.977 0.792 Mlig455_010882 {REF} {Length: 1818} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=33.2]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=18.7]} {Smed: dd_Smed_v6_26560_0_2, dd_Smed_v6_26560_0_2, [Score=102, Expect=9e-24]} {RNA1310_45713} {RNA815_35716}
56. MligTC455_46430 62 1.29 Mlig455_057117, Mlig455_069301

Neo: -

Age: -

GUCY2F 1.766 - - - - 0.965 0.801

Mlig455_057117 {REF} {Length: 2651} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=196.0]; Nitrate and nitrite sensing [PF08376.12, score=82.5]; Heme NO binding associated [PF07701.16, score=28.2]} {Human: ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=247, Expect=9e-70]; ENSG00000169418, NPR1, natriuretic peptide receptor 1, [Score=242, Expect=3e-68]; ENSG00000159899, NPR2, natriuretic peptide receptor 2, [Score=238, Expect=5e-67]} {Mouse: ENSMUSG00000042282, Gucy2f, guanylate cyclase 2f, [Score=246, Expect=7e-70]; ENSMUSG00000027931, Npr1, natriuretic peptide receptor 1, [Score=242, Expect=2e-68]; ENSMUSG00000020890, Gucy2e, guanylate cyclase 2e, [Score=241, Expect=7e-68]; ENSMUSG00000028469, Npr2, natriuretic peptide receptor 2, [Score=239, Expect=3e-67]} {Dmel: FBgn0053958, CG33958, [Score=266, Expect=4e-79]} {Celegans: WBGene00001547, gcy-22, Receptor-type guanylate cyclase gcy-22, [Score=235, Expect=3e-66]} {Smed: dd_Smed_v6_14331_0_1, dd_Smed_v6_14331_0_1, [Score=238, Expect=4e-67]} {RNA1509_38781} {RNA1310_35456} {RNA815_22108}

Mlig455_069301 {REF} {Length: 2370} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=178.1]; Nitrate and nitrite sensing [PF08376.12, score=82.3]; Heme NO binding associated [PF07701.16, score=28.0]} {Human: ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=232, Expect=2e-64]} {Mouse: ENSMUSG00000042282, Gucy2f, guanylate cyclase 2f, [Score=232, Expect=1e-64]; ENSMUSG00000020890, Gucy2e, guanylate cyclase 2e, [Score=225, Expect=5e-62]} {Dmel: FBgn0053958, CG33958, [Score=250, Expect=5e-73]} {Celegans: WBGene00001547, gcy-22, Receptor-type guanylate cyclase gcy-22, [Score=223, Expect=1e-61]} {Smed: dd_Smed_v6_14331_0_1, dd_Smed_v6_14331_0_1, [Score=221, Expect=4e-61]} {RNA1509_38781} {RNA1310_35456} {RNA815_24181}
57. MligTC455_48569 31 0.65 Mlig455_066874

Neo: -

Age: -

1.766 - - - - 0.955 0.811 Mlig455_066874 {REF} {Length: 1074} {NoTransDecoderORF} {RNA1310_59259}
58. MligTC455_15184 33 0.69 Mlig455_065087

Neo: -

Age: -

1.765 - - - - 0.965 0.800 Mlig455_065087 {REF} {Length: 2555} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=183.3]} {Mouse: ENSMUSG00000030340, Scnn1a, sodium channel, nonvoltage-gated 1 alpha, [Score=48.5, Expect=1e-05]} {Celegans: WBGene00009073, delm-1, DEgenerin Linked to Mechanosensation, [Score=68.2, Expect=1e-11]} {Smed: dd_Smed_v6_37545_0_1, dd_Smed_v6_37545_0_1, [RH, Score=125, Expect=3e-30]} {RNA1310_11413} {RNA815_11497}
59. MligTC455_04273 1905 39.69 Mlig455_014980, Mlig455_027959, Mlig455_027986, Mlig455_042890, Mlig455_056217

Neo: -

Age: logFC(26M/2M)=0.365

Region-enriched R4: 1.233/0.00679

1.764 - - 0.953 - - 0.811

Mlig455_014980 {REF} {Length: 2410} {TRANSSPLICED} {Pfam: Plasmid protein of unknown function (Plasmid_RAQPRD) [PF09686.12, score=24.0]} {RNA1509_7158} {RNA1310_4079} {RNA815_282.1}

Mlig455_027959 {REF} {Length: 3263} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4806) [PF16064.7, score=33.3]} {RNA1509_33750} {RNA1310_4079} {RNA815_20382}

Mlig455_027986 {REF} {Length: 3151} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4806) [PF16064.7, score=33.3]} {RNA1509_33750} {RNA1310_4079} {RNA815_20382}

Mlig455_042890 {REF} {Length: 2273} {RNA1509_7158} {RNA1310_4079} {RNA815_282.1}

Mlig455_056217 {REF} {Length: 3151} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4806) [PF16064.7, score=33.3]} {RNA1509_33750} {RNA1310_4079} {RNA815_20382}
60. MligTC455_50694 602 12.54 Mlig455_058794, Mlig455_070066

Neo: -

Age: Down-Down-Up

Region-specific R2: 5.478

Region-enriched R2: 3.805/0.01454

1.764 - - - - 0.963 0.801

Mlig455_058794 {REF} {Length: 776} {RNA1310_76208} {RNA815_49041}

Mlig455_070066 {REF} {Length: 781} {RNA1310_76208} {RNA815_49041}
61. MligTC455_43715 48 0.99 Mlig455_034191

Neo: -

Age: Down-Up-Down

Region-enriched R2: 7.969/0.00817

1.76 - - - - 0.970 0.790 Mlig455_034191 {REF} {Length: 895} {Pfam: WSC domain [PF01822.21, score=39.9]; PAN domain [PF14295.8, score=21.0]; PAN domain [PF00024.28, score=19.9]} {RNA1310_46313} {RNA815_23250}
62. MligTC455_24844 70 1.45 Mlig455_016641, Mlig455_035592

Neo: -

Age: -

Region-enriched R4: 2.424/0.04540

1.758 - - - 0.792 0.966 -

Mlig455_016641 {REF} {Length: 2405} {Pfam: Calcium-activated potassium channel, beta subunit [PF03185.17, score=70.0]} {Smed: dd_Smed_v6_14020_0_1, dd_Smed_v6_14020_0_1, [RH, Score=145, Expect=5e-44]} {RNA1509_2024} {RNA1310_10624} {RNA815_8671}

Mlig455_035592 {REF} {Length: 632} {Pfam: Calcium-activated potassium channel, beta subunit [PF03185.17, score=70.0]} {Smed: dd_Smed_v6_14020_0_1, dd_Smed_v6_14020_0_1, [RH, Score=145, Expect=5e-44]} {RNA1310_10624} {RNA815_27265}
63. MligTC455_31453 322 6.7 Mlig455_045794, Mlig455_063190

Neo: -

Age: -

MMD 1.758 - - - - 0.951 0.807

Mlig455_045794 {REF} {Length: 1920} {TRANSSPLICED} {Pfam: Haemolysin-III related [PF03006.22, score=51.5]} {Human: ENSG00000108960, MMD, monocyte to macrophage differentiation associated, [Score=104, Expect=7e-27]; ENSG00000136297, MMD2, monocyte to macrophage differentiation associated 2, [Score=103, Expect=1e-26]} {Mouse: ENSMUSG00000039533, Mmd2, monocyte to macrophage differentiation-associated 2, [Score=105, Expect=3e-27]; ENSMUSG00000003948, Mmd, monocyte to macrophage differentiation-associated, [Score=104, Expect=3e-27]} {Dmel: FBgn0029935, CG4615, [Score=109, Expect=1e-28]} {Celegans: WBGene00022158, Y71G12B.23, [Score=105, Expect=2e-27]} {Smed: dd_Smed_v6_10316_0_1, dd_Smed_v6_10316_0_1, [Score=133, Expect=1e-38]} {RNA1509_50956} {RNA1310_36731} {RNA815_18300}

Mlig455_063190 {REF} {Length: 1860} {NoTransDecoderORF} {RNA1310_41509} {RNA815_22362}
64. MligTC455_14843 19 0.39 Mlig455_064713

Neo: -

Age: -

1.756 - - - - 0.966 0.790 Mlig455_064713 {REF} {Length: 1584} {RNA1310_60383} {RNA815_48502}
65. MligTC455_31901 18 0.38 Mlig455_022355

Neo: -

Age: -

1.756 - - - - 0.966 0.790 Mlig455_022355 {REF} {Length: 541} {Pfam: PAN domain [PF00024.28, score=19.0]} {RNA1310_125793} {RNA815_23776.1}
66. MligTC455_45487 110 2.3 Mlig455_004129, Mlig455_060457

Neo: -

Age: -

1.754 - - - - 0.960 0.794

Mlig455_004129 {REF} {Length: 1131} {Pfam: PAN domain [PF00024.28, score=18.8]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=64.3, Expect=2e-12]} {RNA1310_37660} {RNA815_17816.1}

Mlig455_060457 {REF} {Length: 1507} {Pfam: PAN domain [PF00024.28, score=19.5]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=64.3, Expect=2e-12]} {RNA1509_54623} {RNA1310_33480} {RNA815_17816.1}
67. MligTC455_18945 41 0.86 Mlig455_031602

Neo: -

Age: -

1.753 - - - - 0.963 0.790 Mlig455_031602 {REF} {Length: 914} {RNA1310_75361} {RNA815_24378}
68. MligTC455_42427 30 0.63 Mlig455_040552, Mlig455_062085

Neo: -

Age: -

ANGPT1, ANGPTL2 1.752 - - - - 0.961 0.791

Mlig455_040552 {REF} {Length: 1447} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=132.5]} {Human: ENSG00000154188, ANGPT1, angiopoietin 1, [Score=108, Expect=3e-26]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=108, Expect=3e-26]; ENSG00000171819, ANGPTL7, angiopoietin like 7, [Score=108, Expect=4e-27]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=104, Expect=8e-25]} {Mouse: ENSMUSG00000028989, Angptl7, angiopoietin-like 7, [Score=110, Expect=4e-28]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=108, Expect=2e-26]; ENSMUSG00000022309, Angpt1, angiopoietin 1, [Score=108, Expect=3e-26]; ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=105, Expect=3e-25]} {Dmel: FBgn0030163, CG1791, [Score=94.4, Expect=3e-23]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=90.1, Expect=3e-20]} {RNA1310_118725}

Mlig455_062085 {REF} {Length: 1538} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=130.9]} {Human: ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=108, Expect=4e-26]; ENSG00000171819, ANGPTL7, angiopoietin like 7, [Score=108, Expect=5e-27]; ENSG00000154188, ANGPT1, angiopoietin 1, [Score=107, Expect=7e-26]; ENSG00000130812, ANGPTL6, angiopoietin like 6, [Score=105, Expect=2e-25]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=103, Expect=2e-24]} {Mouse: ENSMUSG00000028989, Angptl7, angiopoietin-like 7, [Score=110, Expect=5e-28]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=108, Expect=2e-26]; ENSMUSG00000022309, Angpt1, angiopoietin 1, [Score=107, Expect=7e-26]} {Dmel: FBgn0030163, CG1791, [Score=93.6, Expect=5e-23]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=89.4, Expect=5e-20]} {RNA1310_118725}
69. MligTC455_50778 36 0.76 Mlig455_042296

Neo: -

Age: -

GPR50 1.748 - - - - 0.963 0.785 Mlig455_042296 {REF} {Length: 1415} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=116.3]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=40.0]; Olfactory receptor [PF13853.8, score=34.3]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=33.9]} {Human: ENSG00000102195, GPR50, G protein-coupled receptor 50, [Score=124, Expect=4e-31]; ENSG00000134640, MTNR1B, melatonin receptor 1B, [Score=119, Expect=2e-30]} {Mouse: ENSMUSG00000054764, Mtnr1a, melatonin receptor 1A, [Score=120, Expect=4e-31]; ENSMUSG00000056380, Gpr50, G-protein-coupled receptor 50, [Score=119, Expect=2e-29]; ENSMUSG00000050901, Mtnr1b, melatonin receptor 1B, [Score=118, Expect=5e-30]} {Dmel: FBgn0038980, Octbeta1R, Octopamine beta1 receptor, [Score=92.0, Expect=1e-20]} {Celegans: WBGene00006428, tkr-3, TachyKinin Receptor family, [Score=69.7, Expect=4e-13]} {Smed: dd_Smed_v6_65999_0_1, dd_Smed_v6_65999_0_1, [Score=84.7, Expect=1e-18]} {RNA1310_66047} {RNA815_34066}
70. MligTC455_50455 972 20.25 Mlig455_070346

Neo: -

Age: -

Region-specific R2: 4.855

Region-enriched R2: 5.186/0.00000

1.747 - - - - 0.962 0.785 Mlig455_070346 {REF} {Length: 932} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=34.4]; Nematode insulin-related peptide beta type [PF03488.16, score=21.4]} {RNA1509_18514, RNA1509_58074} {RNA1310_51990, RNA1509_18514, RNA1509_58074} {RNA1509_18514, RNA1509_58074, RNA815_25071}
71. MligTC455_43979 188 3.92 Mlig455_000082, Mlig455_063749

Neo: -

Age: -

GHSR 1.746 - - - - 0.953 0.793

Mlig455_000082 {REF} {Length: 1342} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=53.1]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=18.2]} {Human: ENSG00000121853, GHSR, growth hormone secretagogue receptor, [Score=52.0, Expect=7e-07]} {Mouse: ENSMUSG00000051136, Ghsr, growth hormone secretagogue receptor, [Score=50.4, Expect=2e-06]} {Celegans: WBGene00018798, gnrr-1, GoNadotropin-Releasing hormone Receptor (GnRHR) related, [Score=48.9, Expect=3e-06]} {Smed: dd_Smed_v6_60346_0_1, dd_Smed_v6_60346_0_1, [RH, Score=160, Expect=9e-47]} {RNA1310_30553}

Mlig455_063749 {REF} {Length: 1323} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=48.3]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=20.4]} {Smed: dd_Smed_v6_60346_0_1, dd_Smed_v6_60346_0_1, [RH, Score=157, Expect=1e-45]} {RNA1310_30553}
72. MligTC455_44966 574 11.95 Mlig455_036578, Mlig455_057773

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.756

Region-specific R2: 7.016

Region-enriched R2: 7.690/0.00000

1.744 - - - - 0.953 0.791

Mlig455_036578 {REF} {Length: 1101} {RNA1509_34765} {RNA1310_57079} {RNA815_29388}

Mlig455_057773 {REF} {Length: 629} {RNA1509_34765} {RNA1310_57079, RNA1509_34765} {RNA1509_34765, RNA815_29388}
73. MligTC455_41382 65 1.35 Mlig455_022554

Neo: -

Age: -

Region-enriched R2: 5.596/0.01432

1.74 - - - - 0.950 0.790 Mlig455_022554 {REF} {Length: 503} {Pfam: Pancreatic hormone peptide [PF00159.20, score=18.9]} {RNA1310_81495} {RNA815_42745}
74. MligTC455_43984 91 1.9 Mlig455_041471

Neo: -

Age: -

ENTPD5 1.735 - - 0.957 - - 0.778 Mlig455_041471 {REF} {Length: 3234} {Pfam: GDA1/CD39 (nucleoside phosphatase) family [PF01150.19, score=158.7]} {Human: ENSG00000187097, ENTPD5, ectonucleoside triphosphate diphosphohydrolase 5, [Score=129, Expect=3e-32]} {Mouse: ENSMUSG00000021236, Entpd5, ectonucleoside triphosphate diphosphohydrolase 5, [Score=123, Expect=5e-30]; ENSMUSG00000033068, Entpd6, ectonucleoside triphosphate diphosphohydrolase 6, [Score=122, Expect=1e-29]} {Dmel: FBgn0024947, NTPase, [Score=120, Expect=5e-29]} {Celegans: WBGene00016380, ntp-1, Nucleoside-triphosphatase ntp-1, [Score=106, Expect=3e-24]} {Smed: dd_Smed_v6_8855_0_2, dd_Smed_v6_8855_0_2, [Score=117, Expect=3e-28]} {RNA1509_36246} {RNA1310_11342} {RNA815_29784}
75. MligTC455_31273 40 0.83 Mlig455_017570

Neo: -

Age: -

JMJD6 1.734 - - - - 0.957 0.777 Mlig455_017570 {REF} {Length: 2550} {Pfam: Cupin-like domain [PF13621.8, score=84.8]; JmjC domain, hydroxylase [PF02373.24, score=41.9]; Cupin superfamily protein [PF08007.14, score=22.1]} {Human: ENSG00000070495, JMJD6, jumonji domain containing 6, arginine demethylase and lysine hydroxylase, [Score=81.6, Expect=3e-16]} {Mouse: ENSMUSG00000056962, Jmjd6, jumonji domain containing 6, [Score=79.0, Expect=2e-15]} {Dmel: FBgn0038948, PSR, phosphatidylserine receptor, [Score=77.8, Expect=3e-15]} {Celegans: WBGene00004205, psr-1, Bifunctional arginine demethylase and lysyl-hydroxylase psr-1, [Score=88.6, Expect=6e-19]} {Smed: dd_Smed_v6_12267_0_1, dd_Smed_v6_12267_0_1, [RH, Score=327, Expect=7e-108]} {RNA1310_17984} {RNA815_15470}
76. MligTC455_26411 55 1.14 Mlig455_024911

Neo: -

Age: -

1.726 - - - 0.764 0.962 - Mlig455_024911 {REF} {Length: 2411} {Pfam: SH3 domain [PF00018.30, score=28.9]; Variant SH3 domain [PF14604.8, score=22.2]; Variant SH3 domain [PF07653.19, score=22.1]} {Smed: dd_Smed_v6_8729_0_1, dd_Smed_v6_8729_0_1, [RH, Score=60.1, Expect=5e-10]} {RNA1310_32104} {RNA815_32970}
77. MligTC455_42256 163 3.39 Mlig455_054046

Neo: -

Age: Down-Up-Up

LDB2 1.725 - - - - 0.957 0.768 Mlig455_054046 {REF} {Length: 2089} {Pfam: LIM-domain binding protein [PF01803.18, score=164.3]; LIM interaction domain (LID) [PF17916.3, score=55.5]} {Human: ENSG00000169744, LDB2, LIM domain binding 2, [RH, Score=390, Expect=4e-132]} {Mouse: ENSMUSG00000039706, Ldb2, LIM domain binding 2, [RH, Score=388, Expect=3e-131]} {Dmel: FBgn0013764, Chi, Chip, [RH, Score=332, Expect=9e-107]} {Celegans: WBGene00002261, ldb-1, F58A3.1a; LIM Domain Binding protein, [RH, Score=155, Expect=2e-40]} {Smed: dd_Smed_v6_3678_0_1, dd_Smed_v6_3678_0_1, [Score=321, Expect=1e-102]} {RNA1310_27326} {RNA815_22302}
78. MligTC455_31847 661 13.78 Mlig455_025501, Mlig455_070503

Neo: -

Age: Down-Up-Down

KCNMA1 1.723 - - 0.957 0.766 - -

Mlig455_025501 {REF} {Length: 4552} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=85.2]; Ion channel [PF07885.18, score=43.4]; Ion transport protein [PF00520.33, score=34.6]; TrkA-N domain [PF02254.20, score=22.5]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=488, Expect=4e-154]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=335, Expect=3e-97]} {Dmel: FBgn0003429, slo, slowpoke, [Score=484, Expect=1e-151]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=454, Expect=9e-141]} {Smed: dd_Smed_v6_5509_0_1, dd_Smed_v6_5509_0_1, [Score=476, Expect=1e-149]} {RNA1509_14763} {RNA1310_2844.1} {RNA815_830}

Mlig455_070503 {REF} {Length: 4866} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=85.2]; Ion channel [PF07885.18, score=43.4]; Ion transport protein [PF00520.33, score=34.6]; TrkA-N domain [PF02254.20, score=22.5]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=488, Expect=4e-154]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=335, Expect=3e-97]} {Dmel: FBgn0003429, slo, slowpoke, [Score=484, Expect=1e-151]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=454, Expect=9e-141]} {Smed: dd_Smed_v6_5509_0_1, dd_Smed_v6_5509_0_1, [Score=476, Expect=1e-149]} {RNA1509_14763} {RNA1310_2844.1, RNA1509_14763} {RNA1509_14763, RNA815_830}
79. MligTC455_40340 201 4.19 Mlig455_021026, Mlig455_021062

Neo: -

Age: -

1.714 - - - 0.757 0.957 -

Mlig455_021026 {REF} {Length: 1609} {RNA1310_21018} {RNA815_22069}

Mlig455_021062 {REF} {Length: 1582} {RNA1310_21018} {RNA815_22069}
80. MligTC455_30634 114 2.38 Mlig455_025888

Neo: -

Age: Up-Down-Up

Region-enriched R2: 6.750/0.00140

1.71 - - - - 0.962 0.748 Mlig455_025888 {REF} {Length: 5266} {Pfam: Integrase core domain [PF00665.28, score=50.8]; DDE superfamily endonuclease [PF13358.8, score=22.0]} {Smed: dd_Smed_v6_1574_6_72, dd_Smed_v6_1574_6_72, [Score=149, Expect=3e-41]} {RNA1509_47056} {RNA1310_5710.1} {RNA815_6291.1}
81. MligTC455_18599 119 2.47 Mlig455_031197

Neo: -

Age: Down-Up-Up

Region-enriched R2: 4.553/0.00808

1.709 - - - 0.752 0.957 - Mlig455_031197 {REF} {Length: 1284} {RNA1310_35452}
82. MligTC455_12511 68 1.42 Mlig455_017662

Neo: -

Age: -

1.704 - - - - 0.951 0.753 Mlig455_017662 {REF} {Length: 906} {RNA1310_37507} {RNA815_32171}
83. MligTC455_46543 178 3.7 Mlig455_000344, Mlig455_067946

Neo: -

Age: -

Region-specific R2: 6.098

Region-enriched R2: 6.851/0.00000

1.704 - - - 0.744 0.960 -

Mlig455_000344 {REF} {Length: 1920} {RNA1310_82457} {RNA815_33120}

Mlig455_067946 {REF} {Length: 1217} {RNA1310_99435}
84. MligTC455_36853 202 4.21 Mlig455_043548

Neo: -

Age: -

CCDC191 1.699 - - 0.960 - - 0.739 Mlig455_043548 {REF} {Length: 4123} {TRANSSPLICED} {Human: ENSG00000163617, CCDC191, coiled-coil domain containing 191, [Score=115, Expect=1e-25]} {Mouse: ENSMUSG00000022701, Ccdc191, coiled-coil domain containing 191, [RH, Score=95.9, Expect=1e-19]} {Dmel: FBgn0031496, CG17258, [RH, Score=56.2, Expect=1e-07]} {Smed: dd_Smed_v6_8967_0_2, dd_Smed_v6_8967_0_2, [Score=136, Expect=1e-32]} {RNA1509_15334, RNA1509_39248} {RNA1310_1501.1, RNA1509_15334} {RNA1509_15334, RNA815_1513}
85. MligTC455_47230 248 5.17 Mlig455_045999

Neo: -

Age: -

RERGL 1.689 - - - 0.985 - 0.704 Mlig455_045999 {REF} {Length: 1314} {Pfam: Ras family [PF00071.24, score=84.2]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=38.6]} {Human: ENSG00000111404, RERGL, RERG like, [RH, Score=92.4, Expect=2e-22]} {Mouse: ENSMUSG00000092164, Rergl, RERG/RAS-like, [RH, Score=103, Expect=6e-27]} {Dmel: FBgn0035711, CG8519, [Score=90.1, Expect=1e-21]} {Celegans: WBGene00004308, rap-2, RAP homolog (Vertebrate Rap GTPase family), [Score=75.5, Expect=1e-16]} {Smed: dd_Smed_v6_7273_0_1, dd_Smed_v6_7273_0_1, [RH, Score=97.1, Expect=2e-24]} {RNA1310_27799} {RNA815_42256}
86. MligTC455_47949 48 1 Mlig455_026482, Mlig455_026492

Neo: -

Age: -

CHRNA3 1.688 - - - 0.727 0.961 -

Mlig455_026482 {REF} {Length: 2240} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=248.1]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=225.1]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=398, Expect=8e-133]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=382, Expect=5e-127]; ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=382, Expect=2e-126]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=398, Expect=4e-133]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=397, Expect=5e-133]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=384, Expect=1e-127]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [Score=473, Expect=1e-161]} {Celegans: WBGene00006797, unc-63, Acetylcholine receptor subunit alpha-type unc-63, [Score=445, Expect=7e-152]} {Smed: dd_Smed_v6_9799_0_1, dd_Smed_v6_9799_0_1, [Score=416, Expect=2e-140]} {RNA1310_45284} {RNA815_36657}

Mlig455_026492 {REF} {Length: 1090} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=248.1]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=225.1]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=398, Expect=8e-133]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=382, Expect=5e-127]; ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=382, Expect=2e-126]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=398, Expect=4e-133]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=397, Expect=5e-133]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=384, Expect=1e-127]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [Score=473, Expect=1e-161]} {Celegans: WBGene00006797, unc-63, Acetylcholine receptor subunit alpha-type unc-63, [Score=445, Expect=7e-152]} {Smed: dd_Smed_v6_9799_0_1, dd_Smed_v6_9799_0_1, [Score=416, Expect=2e-140]} {RNA1310_45284} {RNA815_36657}
87. MligTC455_46155 116 2.42 Mlig455_027239

Neo: -

Age: -

Region-enriched R2: 4.163/0.03818

GRK3 1.683 0.717 - - - 0.966 - Mlig455_027239 {REF} {Length: 2919} {Pfam: Protein kinase domain [PF00069.27, score=226.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=100.5]; Regulator of G protein signaling domain [PF00615.21, score=48.3]} {Human: ENSG00000100077, GRK3, G protein-coupled receptor kinase 3, [Score=845, Expect=0.0]; ENSG00000173020, GRK2, G protein-coupled receptor kinase 2, [Score=838, Expect=0.0]} {Mouse: ENSMUSG00000042249, Grk3, G protein-coupled receptor kinase 3, [Score=838, Expect=0.0]; ENSMUSG00000024858, Grk2, G protein-coupled receptor kinase 2, [Score=838, Expect=0.0]} {Dmel: FBgn0260798, Gprk1, G protein-coupled receptor kinase 1, [Score=842, Expect=0.0]} {Celegans: WBGene00001709, grk-2, G protein-coupled receptor kinase 2, [Score=819, Expect=0.0]} {Smed: dd_Smed_v6_6480_0_1, dd_Smed_v6_6480_0_1, [Score=949, Expect=0.0]} {RNA1509_7002} {RNA1310_16658} {RNA815_28070}
88. MligTC455_38042 175 3.64 Mlig455_032349

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.633

ANKRD28 1.682 - - 0.958 - - 0.724 Mlig455_032349 {REF} {Length: 2134} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=114.5]; Ankyrin repeats (many copies) [PF13637.8, score=79.6]; Ankyrin repeats (many copies) [PF13857.8, score=77.6]; Ankyrin repeat [PF00023.32, score=64.8]; Ankyrin repeat [PF13606.8, score=61.6]} {Human: ENSG00000206560, ANKRD28, ankyrin repeat domain 28, [Score=67.4, Expect=2e-11]; ENSG00000203780, FANK1, fibronectin type III and ankyrin repeat domains 1, [Score=65.9, Expect=2e-11]} {Mouse: ENSMUSG00000014496, Ankrd28, ankyrin repeat domain 28, [Score=67.4, Expect=1e-11]} {Dmel: FBgn0039590, CG10011, [Score=61.2, Expect=9e-10]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=50.8, Expect=1e-06]} {Smed: dd_Smed_v6_2072_0_29, dd_Smed_v6_2072_0_29, [Score=58.9, Expect=2e-09]} {RNA1509_50870} {RNA1310_30962} {RNA815_23812}
89. MligTC455_47913 139 2.89 Mlig455_025678

Neo: -

Age: Up-Down-Up

Region-enriched R2: 4.279/0.00526
Region-enriched R4: 3.529/0.01391

1.675 0.718 - - - 0.957 - Mlig455_025678 {REF} {Length: 634} {RNA1310_78201} {RNA815_41088}
90. MligTC455_43140 1841 38.34 Mlig455_031799, Mlig455_047599

Neo: -

Age: -

Region-enriched R8: 3.365/0.00001
Region-enriched R2: 2.285/0.02720

GNAS 1.674 - - - 0.714 0.960 -

Mlig455_031799 {REF} {Length: 1853} {Pfam: G-protein alpha subunit [PF00503.22, score=342.0]; ADP-ribosylation factor family [PF00025.23, score=58.4]; Gtr1/RagA G protein conserved region [PF04670.14, score=24.9]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=19.9]} {Human: ENSG00000087460, GNAS, GNAS complex locus, [RH, Score=514, Expect=0.0]; ENSG00000141404, GNAL, G protein subunit alpha L, [RH, Score=506, Expect=1e-179]} {Mouse: ENSMUSG00000027523, Gnas, GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, [RH, Score=512, Expect=0.0]; ENSMUSG00000024524, Gnal, guanine nucleotide binding protein, alpha stimulating, olfactory type, [RH, Score=510, Expect=0.0]} {Dmel: FBgn0001123, Galphas, G protein alpha s subunit, [RH, Score=511, Expect=0.0]} {Celegans: WBGene00001745, gsa-1, G protein, Subunit Alpha, [RH, Score=469, Expect=2e-165]} {Smed: dd_Smed_v6_6167_0_1, dd_Smed_v6_6167_0_1, [RH, Score=540, Expect=0.0]} {RNA1509_55942} {RNA1310_13501} {RNA815_7904}

Mlig455_047599 {REF} {Length: 1095} {RNA1509_25915, RNA1509_33730} {RNA1310_45973, RNA1509_25915, RNA1509_33730} {RNA1509_25915, RNA1509_33730, RNA815_22813}
91. MligTC455_46881 15 0.32 Mlig455_061546

Neo: -

Age: Down-Up-Up

IAH1 1.672 - - - 0.713 0.959 - Mlig455_061546 {REF} {Length: 1647} {Pfam: GDSL-like Lipase/Acylhydrolase family [PF13472.8, score=76.2]; GDSL-like Lipase/Acylhydrolase [PF00657.24, score=32.9]} {Human: ENSG00000134330, IAH1, isoamyl acetate hydrolyzing esterase 1 (putative), [Score=139, Expect=6e-40]} {Mouse: ENSMUSG00000062054, Iah1, isoamyl acetate-hydrolyzing esterase 1 homolog, [Score=122, Expect=1e-33]} {Smed: dd_Smed_v6_6241_0_1, dd_Smed_v6_6241_0_1, [Score=112, Expect=2e-30]} {RNA1310_108127} {RNA815_31492}
92. MligTC455_49793 54 1.12 Mlig455_000683, Mlig455_000735, Mlig455_034198

Neo: -

Age: -

KREMEN1 1.669 - - - 0.715 0.954 -

Mlig455_000683 {REF} {Length: 1382} {Pfam: WSC domain [PF01822.21, score=48.5]; PAN-like domain [PF08277.14, score=21.1]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=53.1, Expect=5e-07]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=54.3, Expect=1e-07]} {RNA1310_39474.2} {RNA815_58746}

Mlig455_000735 {REF} {Length: 1490} {Pfam: WSC domain [PF01822.21, score=36.2]; PAN domain [PF00024.28, score=20.9]} {RNA1310_36702.1} {RNA815_58746}

Mlig455_034198 {REF} {Length: 685} {Pfam: WSC domain [PF01822.21, score=42.1]; PAN domain [PF00024.28, score=19.0]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=52.8, Expect=1e-07]} {RNA1310_148883} {RNA815_58746}
93. MligTC455_27678 355 7.4 Mlig455_070610

Neo: -

Age: -

Region-specific R2: 4.724

Region-enriched R2: 3.766/0.00062

1.654 - - - 0.700 0.954 - Mlig455_070610 {REF} {Length: 725} {RNA1509_17468, RNA1509_34237} {RNA1310_59474, RNA1509_17468, RNA1509_34237} {RNA1509_17468, RNA1509_34237, RNA815_28024}
94. MligTC455_26074 4 0.08 Mlig455_007443

Neo: -

Age: -

0.987 - - - - 0.987 - Mlig455_007443 {REF} {Length: 3942} {Pfam: RNase H-like domain found in reverse transcriptase [PF17917.3, score=94.5]; RNase H-like domain found in reverse transcriptase [PF17919.3, score=91.3]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=55.8]; Aspartyl protease [PF13650.8, score=23.3]; gag-polyprotein putative aspartyl protease [PF13975.8, score=22.1]} {Smed: dd_Smed_v6_1574_6_40, dd_Smed_v6_1574_6_40, [Score=180, Expect=5e-49]} {RNA1509_34968} {RNA1310_827, RNA1509_34968} {RNA1509_34968, RNA815_6876}
95. MligTC455_56231 7 0.14 Mlig455_043876

Neo: -

Age: -

0.987 - - - - 0.987 - Mlig455_043876 {REF} {Length: 577} {RNA1310_34857} {RNA815_56033}
96. MligTC455_02154 8 0.16 Mlig455_000640

Neo: Irradiation

Age: Up-Down-Down

TTC17 0.986 - - - - 0.986 - Mlig455_000640 {REF} {Length: 3975} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF07719.19, score=35.8]; Tetratricopeptide repeat [PF00515.30, score=33.6]; Tetratricopeptide repeat [PF13176.8, score=29.2]; Tetratricopeptide repeat [PF13424.8, score=23.7]; TPR repeat [PF13414.8, score=21.7]} {Human: ENSG00000052841, TTC17, tetratricopeptide repeat domain 17, [RH, Score=159, Expect=5e-39]} {Mouse: ENSMUSG00000027194, Ttc17, tetratricopeptide repeat domain 17, [RH, Score=160, Expect=2e-39]} {Dmel: FBgn0029713, CG11436, [RH, Score=62.8, Expect=1e-09]} {Celegans: WBGene00020553, T19A5.1, [RH, Score=57.0, Expect=9e-08]} {Smed: dd_Smed_v6_11405_0_1, dd_Smed_v6_11405_0_1, [RH, Score=258, Expect=5e-71]} {RNA1509_10619, RNA1509_58302} {RNA1310_1270.1, RNA1509_10619, RNA1509_58302} {RNA1509_10619, RNA1509_58302, RNA815_24250}
97. MligTC455_50739 250 5.21 Mlig455_065687

Neo: -

Age: logFC(26M/2M)=-0.618

Region-enriched R2: 2.479/0.00468

0.983 - - 0.983 - - - Mlig455_065687 {REF} {Length: 2063} {RNA1509_47916, RNA1509_50080} {RNA1310_26797, RNA1509_47916, RNA1509_50080} {RNA1509_47916, RNA1509_50080, RNA815_45485}
98. MligTC455_04855 16 0.34 Mlig455_005010, Mlig455_005053, Mlig455_005260

Neo: -

Age: logFC(26M/2M)=0.904

HCRTR2 0.982 - - - - 0.982 -

Mlig455_005010 {REF} {Length: 1532} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=156.6]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=29.4]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=25.7]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=23.9]} {Human: ENSG00000137252, HCRTR2, hypocretin receptor 2, [RH, Score=207, Expect=5e-61]} {Mouse: ENSMUSG00000032360, Hcrtr2, hypocretin (orexin) receptor 2, [Score=209, Expect=7e-62]} {Dmel: FBgn0038880, SIFaR, SIFamide receptor, [Score=150, Expect=8e-39]} {Celegans: WBGene00022004, npr-22, NeuroPeptide Receptor family, [Score=119, Expect=4e-29]} {Smed: dd_Smed_v6_22624_0_1, dd_Smed_v6_22624_0_1, [RH, Score=215, Expect=7e-65]} {RNA1310_58724} {RNA815_36016}

Mlig455_005053 {REF} {Length: 3639} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=156.6]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=29.4]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=25.7]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=23.9]} {Human: ENSG00000137252, HCRTR2, hypocretin receptor 2, [RH, Score=210, Expect=6e-62]} {Mouse: ENSMUSG00000032360, Hcrtr2, hypocretin (orexin) receptor 2, [Score=211, Expect=1e-62]} {Dmel: FBgn0038880, SIFaR, SIFamide receptor, [Score=150, Expect=7e-39]} {Celegans: WBGene00022004, npr-22, NeuroPeptide Receptor family, [Score=119, Expect=3e-29]} {Smed: dd_Smed_v6_22624_0_1, dd_Smed_v6_22624_0_1, [RH, Score=215, Expect=6e-65]} {RNA1310_58724} {RNA815_36016}

Mlig455_005260 {REF} {Length: 1614} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=156.6]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=29.4]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=25.7]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=23.9]} {Human: ENSG00000137252, HCRTR2, hypocretin receptor 2, [RH, Score=210, Expect=6e-62]} {Mouse: ENSMUSG00000032360, Hcrtr2, hypocretin (orexin) receptor 2, [Score=211, Expect=1e-62]} {Dmel: FBgn0038880, SIFaR, SIFamide receptor, [Score=150, Expect=7e-39]} {Celegans: WBGene00022004, npr-22, NeuroPeptide Receptor family, [Score=119, Expect=3e-29]} {Smed: dd_Smed_v6_22624_0_1, dd_Smed_v6_22624_0_1, [RH, Score=215, Expect=6e-65]} {RNA1310_58724} {RNA815_36016}
99. MligTC455_38581 72 1.49 Mlig455_056022

Neo: -

Age: -

SCNN1B 0.981 - - - - 0.981 - Mlig455_056022 {REF} {Length: 3168} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=200.5]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=72.8, Expect=8e-13]} {Mouse: ENSMUSG00000038276, Asic3, acid-sensing (proton-gated) ion channel 3, [Score=70.9, Expect=2e-12]} {Celegans: WBGene00012116, del-4, DEgenerin Like, [Score=77.8, Expect=7e-15]} {Smed: dd_Smed_v6_31771_0_1, dd_Smed_v6_31771_0_1, [RH, Score=103, Expect=2e-23]} {RNA1509_29577} {RNA1310_8793.1} {RNA815_14483}
100. MligTC455_40156 18 0.38 Mlig455_038693

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.705

0.981 - - - - 0.981 - Mlig455_038693 {REF} {Length: 2831} {RNA1509_1762} {RNA1310_2511} {RNA815_910.1}

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