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Results for MligTC455_41650

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_41650 752 15.67 Mlig455_020540, Mlig455_020590, Mlig455_020592

Neo: -

Age: -

ARMC9

Mlig455_020540 {REF} {Length: 3118} {TRANSSPLICED} {Human: ENSG00000135931, ARMC9, armadillo repeat containing 9, [RH, Score=537, Expect=0.0]} {Mouse: ENSMUSG00000062590, Armc9, armadillo repeat containing 9, [RH, Score=533, Expect=3e-178]} {Smed: dd_Smed_v6_10926_0_1, dd_Smed_v6_10926_0_1, [RH, Score=498, Expect=8e-166]} {RNA1509_54977, RNA1509_9388} {RNA1310_10290, RNA1509_54977} {RNA1509_54977, RNA815_4141}

Mlig455_020590 {REF} {Length: 2939} {TRANSSPLICED} {Human: ENSG00000135931, ARMC9, armadillo repeat containing 9, [RH, Score=539, Expect=0.0]} {Mouse: ENSMUSG00000062590, Armc9, armadillo repeat containing 9, [RH, Score=531, Expect=8e-178]} {Smed: dd_Smed_v6_10926_0_1, dd_Smed_v6_10926_0_1, [RH, Score=499, Expect=3e-166]} {RNA1509_9388} {RNA1310_10290} {RNA815_4141}

Mlig455_020592 {REF} {Length: 1875} {Pfam: HEAT repeat [PF02985.24, score=19.7]} {Human: ENSG00000135931, ARMC9, armadillo repeat containing 9, [Score=227, Expect=3e-66]} {Mouse: ENSMUSG00000062590, Armc9, armadillo repeat containing 9, [Score=225, Expect=1e-65]} {Smed: dd_Smed_v6_10926_0_1, dd_Smed_v6_10926_0_1, [Score=219, Expect=4e-64]} {RNA1509_9388} {RNA1310_10290} {RNA815_4141}

Cumulative graph for MligTC455_41650

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -6.847 4.35 0.04275 0.50048
RegionR2 1.526 4.35 0.01947 0.15049
RegionR3 1.03 4.35 0.12335 0.60574
RegionR4 1.131 4.35 0.12705 0.36003
RegionR5 -0.135 4.35 0.88865 1.00000
RegionR6 0.849 4.35 0.25439 0.83961
RegionR7 1.203 4.35 0.10543 0.61733
RegionR8 1.243 4.35 0.15125 0.70525

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.824 4.35 0.99990 1.00000
RegenerationR2 -0.004 4.35 0.98768 1.00000
RegenerationR3 -0.274 4.35 0.44931 0.83153
RegenerationR4 -0.228 4.35 0.56157 0.89757
RegenerationR5 0.495 4.35 0.18373 0.61395
RegenerationR6 -0.467 4.35 0.21641 0.56066
RegenerationBL -0.551 4.35 0.22862 0.57879
RegenerationTP -1.605 4.35 0.00414 0.10705


Genes with expression patterns similar to MligTC455_41650

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_41650 752 15.67 Mlig455_020540, Mlig455_020590, Mlig455_020592

Neo: -

Age: -

ARMC9 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_020540 {REF} {Length: 3118} {TRANSSPLICED} {Human: ENSG00000135931, ARMC9, armadillo repeat containing 9, [RH, Score=537, Expect=0.0]} {Mouse: ENSMUSG00000062590, Armc9, armadillo repeat containing 9, [RH, Score=533, Expect=3e-178]} {Smed: dd_Smed_v6_10926_0_1, dd_Smed_v6_10926_0_1, [RH, Score=498, Expect=8e-166]} {RNA1509_54977, RNA1509_9388} {RNA1310_10290, RNA1509_54977} {RNA1509_54977, RNA815_4141}

Mlig455_020590 {REF} {Length: 2939} {TRANSSPLICED} {Human: ENSG00000135931, ARMC9, armadillo repeat containing 9, [RH, Score=539, Expect=0.0]} {Mouse: ENSMUSG00000062590, Armc9, armadillo repeat containing 9, [RH, Score=531, Expect=8e-178]} {Smed: dd_Smed_v6_10926_0_1, dd_Smed_v6_10926_0_1, [RH, Score=499, Expect=3e-166]} {RNA1509_9388} {RNA1310_10290} {RNA815_4141}

Mlig455_020592 {REF} {Length: 1875} {Pfam: HEAT repeat [PF02985.24, score=19.7]} {Human: ENSG00000135931, ARMC9, armadillo repeat containing 9, [Score=227, Expect=3e-66]} {Mouse: ENSMUSG00000062590, Armc9, armadillo repeat containing 9, [Score=225, Expect=1e-65]} {Smed: dd_Smed_v6_10926_0_1, dd_Smed_v6_10926_0_1, [Score=219, Expect=4e-64]} {RNA1509_9388} {RNA1310_10290} {RNA815_4141}
2. MligTC455_39612 861 17.93 Mlig455_019206

Neo: -

Age: logFC(26M/2M)=-0.343

DLEC1 4.251 - 0.855 0.877 0.796 0.968 0.755 Mlig455_019206 {REF} {Length: 7152} {TRANSSPLICED} {Pfam: Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin [PF15780.7, score=68.8]; Flagellar-associated PapD-like [PF14874.8, score=25.0]} {Human: ENSG00000008226, DLEC1, DLEC1, cilia and flagella associated protein, [RH, Score=721, Expect=0.0]} {Mouse: ENSMUSG00000038060, Dlec1, deleted in lung and esophageal cancer 1, [RH, Score=725, Expect=0.0]} {Smed: dd_Smed_v6_10833_0_1, dd_Smed_v6_10833_0_1, [RH, Score=813, Expect=0.0]} {RNA1509_3454} {RNA1310_859.1, RNA1509_3454} {RNA1509_3454, RNA815_262}
3. MligTC455_45839 1905 39.68 Mlig455_059781, Mlig455_070317

Neo: -

Age: logFC(26M/2M)=-0.483

LRRC43 4.184 - 0.741 0.892 0.887 0.955 0.709

Mlig455_059781 {REF} {Length: 2388} {TRANSSPLICED} {Pfam: Leucine-rich repeat [PF14580.8, score=39.0]; Leucine Rich repeats (2 copies) [PF12799.9, score=34.8]; Leucine rich repeat [PF13855.8, score=30.9]} {Human: ENSG00000158113, LRRC43, leucine rich repeat containing 43, [RH, Score=202, Expect=2e-55]} {Mouse: ENSMUSG00000063409, Lrrc43, leucine rich repeat containing 43, [RH, Score=216, Expect=9e-61]} {Dmel: FBgn0014395, tilB, touch insensitive larva B, [Score=63.9, Expect=2e-10]} {Smed: dd_Smed_v6_12354_0_1, dd_Smed_v6_12354_0_1, [RH, Score=184, Expect=2e-50]} {RNA1509_3859} {RNA1310_9281, RNA1509_3859} {RNA1509_3859, RNA815_3282}

Mlig455_070317 {REF} {Length: 2398} {TRANSSPLICED} {Pfam: Leucine-rich repeat [PF14580.8, score=39.0]; Leucine Rich repeats (2 copies) [PF12799.9, score=34.8]; Leucine rich repeat [PF13855.8, score=30.8]} {Human: ENSG00000158113, LRRC43, leucine rich repeat containing 43, [RH, Score=200, Expect=5e-55]} {Mouse: ENSMUSG00000063409, Lrrc43, leucine rich repeat containing 43, [RH, Score=213, Expect=1e-59]} {Dmel: FBgn0014395, tilB, touch insensitive larva B, [Score=63.9, Expect=2e-10]} {Smed: dd_Smed_v6_12354_0_1, dd_Smed_v6_12354_0_1, [RH, Score=184, Expect=2e-50]} {RNA1509_3859} {RNA1310_9281} {RNA815_3282}
4. MligTC455_30618 652 13.59 Mlig455_031172

Neo: -

Age: logFC(26M/2M)=-0.520

ITPR2 4.172 - 0.791 0.928 0.792 0.954 0.707 Mlig455_031172 {REF} {Length: 9583} {Pfam: RIH domain [PF01365.23, score=93.8]; Inositol 1,4,5-trisphosphate/ryanodine receptor [PF08709.13, score=76.1]; MIR domain [PF02815.21, score=44.8]} {Human: ENSG00000123104, ITPR2, inositol 1,4,5-trisphosphate receptor type 2, [Score=214, Expect=5e-55]; ENSG00000150995, ITPR1, inositol 1,4,5-trisphosphate receptor type 1, [Score=205, Expect=3e-52]} {Mouse: ENSMUSG00000042644, Itpr3, inositol 1,4,5-triphosphate receptor 3, [Score=222, Expect=2e-57]; ENSMUSG00000030287, Itpr2, inositol 1,4,5-triphosphate receptor 2, [Score=213, Expect=8e-55]} {Dmel: FBgn0010051, Itp-r83A, Inositol 1,4,5,-tris-phosphate receptor, [Score=194, Expect=3e-49]} {Celegans: WBGene00002173, itr-1, Inositol 1,4,5-trisphosphate receptor itr-1, [Score=140, Expect=7e-33]} {Smed: dd_Smed_v6_3814_1_1, dd_Smed_v6_3814_1_1, [Score=1298, Expect=0.0]} {RNA1509_23724, RNA1509_55174, RNA1509_5518} {RNA1310_129.1, RNA1509_23724, RNA1509_55174, RNA1509_5518} {RNA1509_23724, RNA1509_55174, RNA1509_5518, RNA815_62.1}
5. MligTC455_17318 828 17.24 Mlig455_016719

Neo: -

Age: -

Region-enriched R2: 1.905/0.03396

NOXRED1 4.159 0.744 0.733 0.922 0.808 0.952 - Mlig455_016719 {REF} {Length: 1953} {Pfam: NADP oxidoreductase coenzyme F420-dependent [PF03807.19, score=37.8]} {Human: ENSG00000165555, NOXRED1, NADP dependent oxidoreductase domain containing 1, [RH, Score=130, Expect=8e-33]} {Mouse: ENSMUSG00000072919, Noxred1, NADP+ dependent oxidoreductase domain containing 1, [RH, Score=128, Expect=4e-32]} {Smed: dd_Smed_v6_14962_0_1, dd_Smed_v6_14962_0_1, [Score=133, Expect=2e-34]} {RNA1509_13348} {RNA1310_24844} {RNA815_21464}
6. MligTC455_19430 476 9.92 Mlig455_059737

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.749

Region-enriched R2: 1.435/0.03961

WDR49 4.137 - 0.729 0.868 0.714 0.969 0.857 Mlig455_059737 {REF} {Length: 4068} {Pfam: WD domain, G-beta repeat [PF00400.34, score=25.0]} {Human: ENSG00000174776, WDR49, WD repeat domain 49, [Score=140, Expect=3e-35]} {Mouse: ENSMUSG00000104301, Wdr49, WD repeat domain 49, [Score=130, Expect=1e-31]} {Smed: dd_Smed_v6_5437_0_2, dd_Smed_v6_5437_0_2, [Score=132, Expect=1e-32]} {RNA1509_29401, RNA1509_3708} {RNA1310_2384.2, RNA1509_29401} {RNA1509_29401, RNA815_724.1}
7. MligTC455_53772 1683 35.07 Mlig455_002139, Mlig455_002285

Neo: -

Age: logFC(26M/2M)=-0.320

Region-enriched R4: 1.530/0.00824

Regeneration-downregulated BL: -1.893

Regeneration-depleted BL: -1.893

ERICH3 3.568 - 0.838 0.869 - 0.962 0.899

Mlig455_002139 {REF} {Length: 6481} {TRANSSPLICED} {Pfam: PLAT/LH2 domain [PF01477.25, score=233.0]; Domain of unknown function (DUF4590) [PF15257.8, score=138.1]; Embryo-specific protein 3, (ATS3) [PF06232.13, score=44.0]} {Human: ENSG00000178965, ERICH3, glutamate rich 3, [RH, Score=135, Expect=4e-31]} {Mouse: ENSMUSG00000078161, Erich3, glutamate rich 3, [RH, Score=127, Expect=1e-28]} {Celegans: WBGene00009201, F28C1.3, Protein phosphatase 1 regulatory subunit 37 homolog, [Score=60.1, Expect=1e-08]} {Smed: dd_Smed_v6_8627_0_1, dd_Smed_v6_8627_0_1, [Score=131, Expect=1e-30]} {RNA1509_1640} {RNA1310_1660.1} {RNA815_304.1}

Mlig455_002285 {REF} {Length: 6537} {Pfam: PLAT/LH2 domain [PF01477.25, score=234.5]; Domain of unknown function (DUF4590) [PF15257.8, score=138.4]; Embryo-specific protein 3, (ATS3) [PF06232.13, score=43.7]} {Human: ENSG00000178965, ERICH3, glutamate rich 3, [RH, Score=135, Expect=4e-31]} {Mouse: ENSMUSG00000078161, Erich3, glutamate rich 3, [RH, Score=127, Expect=9e-29]} {Celegans: WBGene00009201, F28C1.3, Protein phosphatase 1 regulatory subunit 37 homolog, [Score=56.2, Expect=2e-07]} {Smed: dd_Smed_v6_8627_0_1, dd_Smed_v6_8627_0_1, [Score=129, Expect=8e-30]} {RNA1509_1640} {RNA1310_3405} {RNA815_304.1}
8. MligTC455_36003 363 7.55 Mlig455_026590

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.251

DNAH6 3.553 - - 0.799 0.923 0.950 0.881 Mlig455_026590 {REF} {Length: 15062} {TRANSSPLICED} {Pfam: Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=480.2]; P-loop containing dynein motor region D4 [PF12780.9, score=291.4]; Dynein heavy chain C-terminal domain [PF18199.3, score=254.7]; ATP-binding dynein motor region [PF12781.9, score=232.9]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=229.2]; P-loop containing dynein motor region [PF12775.9, score=203.3]; Microtubule-binding stalk of dynein motor [PF12777.9, score=125.5]; Dynein heavy chain AAA lid domain [PF18198.3, score=122.2]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=112.7]; Dynein heavy chain AAA lid domain [PF17852.3, score=85.2]; AAA domain (dynein-related subfamily) [PF07728.16, score=50.9]; AAA domain [PF13401.8, score=49.6]; AAA ATPase domain [PF13191.8, score=46.7]; AAA+ lid domain [PF17857.3, score=46.7]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=45.9]; AAA domain [PF13238.8, score=23.0]; AAA domain [PF13671.8, score=20.8]; NACHT domain [PF05729.14, score=20.7]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=19.7]} {Human: ENSG00000115423, DNAH6, dynein axonemal heavy chain 6, [Score=1591, Expect=0.0]; ENSG00000185842, DNAH14, dynein axonemal heavy chain 14, [Score=1554, Expect=0.0]} {Mouse: ENSMUSG00000052861, Dnah6, dynein, axonemal, heavy chain 6, [Score=1545, Expect=0.0]} {Dmel: FBgn0283476, Dhc16F, Dynein heavy chain at 16F, [Score=1207, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=628, Expect=5e-180]} {Smed: dd_Smed_v6_10969_0_1, dd_Smed_v6_10969_0_1, [RH, Score=2792, Expect=0.0]} {RNA1509_3937, RNA1509_49112} {RNA1310_38.1, RNA1509_49112} {RNA1509_49112, RNA815_142}
9. MligTC455_42996 1278 26.63 Mlig455_063418, Mlig455_066633

Neo: -

Age: logFC(26M/2M)=-0.327

Region-enriched R2: 1.738/0.03767

DYRK2 3.481 - 0.848 0.908 0.957 0.768 -

Mlig455_063418 {REF} {Length: 2420} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=193.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=85.6]; ABC1 atypical kinase-like domain [PF03109.18, score=24.3]; Phosphotransferase enzyme family [PF01636.25, score=22.4]; RIO1 family [PF01163.24, score=18.5]} {Human: ENSG00000127334, DYRK2, dual specificity tyrosine phosphorylation regulated kinase 2, [RH, Score=632, Expect=0.0]} {Mouse: ENSMUSG00000028630, Dyrk2, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2, [RH, Score=633, Expect=0.0]} {Dmel: FBgn0027101, Dyrk3, Dual-specificity tyrosine phosphorylation-regulated kinase 3, [RH, Score=542, Expect=0.0]} {Celegans: WBGene00003150, mbk-2, Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2, [RH, Score=577, Expect=0.0]} {Smed: dd_Smed_v6_10966_0_1, dd_Smed_v6_10966_0_1, [RH, Score=612, Expect=0.0]} {RNA1509_27355, RNA1509_7341} {RNA1310_9403, RNA1509_7341} {RNA1509_7341, RNA815_3107}

Mlig455_066633 {REF} {Length: 2424} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=193.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=85.6]; ABC1 atypical kinase-like domain [PF03109.18, score=24.3]; Phosphotransferase enzyme family [PF01636.25, score=22.4]; RIO1 family [PF01163.24, score=18.5]} {Human: ENSG00000127334, DYRK2, dual specificity tyrosine phosphorylation regulated kinase 2, [RH, Score=632, Expect=0.0]} {Mouse: ENSMUSG00000028630, Dyrk2, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2, [RH, Score=633, Expect=0.0]} {Dmel: FBgn0027101, Dyrk3, Dual-specificity tyrosine phosphorylation-regulated kinase 3, [RH, Score=542, Expect=0.0]} {Celegans: WBGene00003150, mbk-2, Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2, [RH, Score=577, Expect=0.0]} {Smed: dd_Smed_v6_10966_0_1, dd_Smed_v6_10966_0_1, [RH, Score=612, Expect=0.0]} {RNA1509_18793, RNA1509_27355} {RNA1310_9403, RNA1509_18793, RNA1509_27355} {RNA1509_18793, RNA1509_27355, RNA815_3107}
10. MligTC455_46255 2218 46.21 Mlig455_024833

Neo: -

Age: logFC(26M/2M)=-0.329

CASC1 3.408 - 0.834 - 0.850 0.953 0.771 Mlig455_024833 {REF} {Length: 2822} {Pfam: Cancer susceptibility candidate 1 N-terminus [PF15927.7, score=170.2]; Cancer susceptibility candidate 1 C-terminal [PF12366.10, score=30.7]} {Human: ENSG00000118307, CASC1, cancer susceptibility 1, [RH, Score=319, Expect=1e-97]} {Mouse: ENSMUSG00000043541, Casc1, cancer susceptibility candidate 1, [RH, Score=293, Expect=5e-88]} {Dmel: FBgn0030889, CG15373, [RH, Score=82.4, Expect=8e-16]} {Smed: dd_Smed_v6_11291_0_1, dd_Smed_v6_11291_0_1, [RH, Score=521, Expect=7e-175]} {RNA1509_1842} {RNA1310_6962.1} {RNA815_2139}
11. MligTC455_36618 545 11.35 Mlig455_020301, Mlig455_020358

Neo: -

Age: logFC(26M/2M)=-0.435

Region-enriched R2: 3.072/0.00097

SLC7A6 3.365 - - 0.872 0.725 0.957 0.811

Mlig455_020301 {REF} {Length: 4137} {Pfam: Amino acid permease [PF13520.8, score=183.8]; Amino acid permease [PF00324.23, score=95.7]} {Human: ENSG00000103064, SLC7A6, solute carrier family 7 member 6, [RH, Score=421, Expect=7e-143]; ENSG00000155465, SLC7A7, solute carrier family 7 member 7, [RH, Score=412, Expect=1e-139]; ENSG00000103257, SLC7A5, solute carrier family 7 member 5, [RH, Score=410, Expect=1e-138]} {Mouse: ENSMUSG00000031904, Slc7a6, solute carrier family 7 (cationic amino acid transporter, y+ system), member 6, [RH, Score=419, Expect=2e-142]; ENSMUSG00000027737, Slc7a11, solute carrier family 7 (cationic amino acid transporter, y+ system), member 11, [RH, Score=413, Expect=3e-140]; ENSMUSG00000000958, Slc7a7, solute carrier family 7 (cationic amino acid transporter, y+ system), member 7, [RH, Score=410, Expect=4e-139]} {Dmel: FBgn0039844, CG1607, [RH, Score=467, Expect=2e-161]} {Celegans: WBGene00000002, aat-1, Amino Acid Transporter, [RH, Score=431, Expect=1e-147]} {Smed: dd_Smed_v6_2179_0_1, dd_Smed_v6_2179_0_1, [RH, Score=498, Expect=5e-174]} {RNA1509_26498} {RNA1310_9422, RNA1509_26498} {RNA1509_26498, RNA815_5493}

Mlig455_020358 {REF} {Length: 3120} {Pfam: Amino acid permease [PF13520.8, score=147.1]; Amino acid permease [PF00324.23, score=74.6]} {Human: ENSG00000103064, SLC7A6, solute carrier family 7 member 6, [Score=346, Expect=6e-115]; ENSG00000155465, SLC7A7, solute carrier family 7 member 7, [Score=340, Expect=2e-112]} {Mouse: ENSMUSG00000031904, Slc7a6, solute carrier family 7 (cationic amino acid transporter, y+ system), member 6, [Score=340, Expect=9e-113]; ENSMUSG00000000958, Slc7a7, solute carrier family 7 (cationic amino acid transporter, y+ system), member 7, [Score=335, Expect=7e-111]; ENSMUSG00000027737, Slc7a11, solute carrier family 7 (cationic amino acid transporter, y+ system), member 11, [Score=325, Expect=6e-107]} {Dmel: FBgn0039844, CG1607, [Score=390, Expect=1e-132]} {Celegans: WBGene00000002, aat-1, Amino Acid Transporter, [Score=353, Expect=2e-118]} {Smed: dd_Smed_v6_7207_0_1, dd_Smed_v6_7207_0_1, [Score=416, Expect=3e-143]} {RNA1509_56112} {RNA1310_9422, RNA1509_56112} {RNA1509_56112, RNA815_5493}
12. MligTC455_53683 2280 47.51 Mlig455_008125, Mlig455_008133

Neo: -

Age: -

ERICH6 3.334 - 0.703 0.873 0.789 0.969 -

Mlig455_008125 {REF} {Length: 2384} {Pfam: FAM194 protein [PF14977.8, score=172.8]; Protein of unknown function (DUF429) [PF04250.15, score=20.3]} {Human: ENSG00000163645, ERICH6, glutamate rich 6, [Score=159, Expect=2e-41]} {Mouse: ENSMUSG00000070471, Erich6, glutamate rich 6, [Score=114, Expect=7e-26]} {Smed: dd_Smed_v6_11097_0_1, dd_Smed_v6_11097_0_1, [RH, Score=229, Expect=3e-66]} {RNA1509_13316} {RNA1310_9580.2} {RNA815_3023.1}

Mlig455_008133 {REF} {Length: 2411} {Pfam: FAM194 protein [PF14977.8, score=172.2]} {Human: ENSG00000163645, ERICH6, glutamate rich 6, [RH, Score=162, Expect=2e-42]} {Mouse: ENSMUSG00000070471, Erich6, glutamate rich 6, [Score=112, Expect=3e-25]} {Smed: dd_Smed_v6_11097_0_1, dd_Smed_v6_11097_0_1, [RH, Score=230, Expect=1e-66]} {RNA1509_15088} {RNA1310_8374} {RNA815_3023.1}
13. MligTC455_19429 537 11.18 Mlig455_016019

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.664

Region-enriched R2: 1.983/0.00165

WDR49 3.324 - - 0.910 0.701 0.960 0.753 Mlig455_016019 {REF} {Length: 4260} {Pfam: WD domain, G-beta repeat [PF00400.34, score=59.6]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=29.3]; EF-hand domain pair [PF13833.8, score=22.2]; EF-hand domain pair [PF13499.8, score=20.7]} {Human: ENSG00000174776, WDR49, WD repeat domain 49, [Score=310, Expect=1e-88]} {Mouse: ENSMUSG00000104301, Wdr49, WD repeat domain 49, [Score=232, Expect=7e-64]; ENSMUSG00000029658, Wdr95, WD40 repeat domain 95, [Score=231, Expect=4e-63]; ENSMUSG00000044083, Efcab8, EF-hand calcium binding domain 8, [Score=226, Expect=9e-60]} {Dmel: FBgn0267449, WDY, WD40 Y, [Score=180, Expect=9e-46]} {Smed: dd_Smed_v6_5437_0_2, dd_Smed_v6_5437_0_2, [Score=306, Expect=3e-87]} {RNA1509_3708} {RNA1310_2384.2, RNA1509_3708} {RNA1509_3708, RNA815_724.1}
14. MligTC455_41103 642 13.38 Mlig455_045043, Mlig455_045057

Neo: -

Age: logFC(26M/2M)=-0.438

NEK11 3.322 0.793 - 0.702 0.965 0.862 -

Mlig455_045043 {REF} {Length: 4762} {Pfam: Protein kinase domain [PF00069.27, score=182.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=134.0]; Ankyrin repeats (3 copies) [PF12796.9, score=71.5]; Ankyrin repeats (many copies) [PF13637.8, score=61.5]; Ankyrin repeats (many copies) [PF13857.8, score=50.6]; Ankyrin repeat [PF00023.32, score=42.2]; Ankyrin repeat [PF13606.8, score=40.6]; Kinase-like [PF14531.8, score=38.6]} {Human: ENSG00000114670, NEK11, NIMA related kinase 11, [Score=179, Expect=6e-49]; ENSG00000136098, NEK3, NIMA related kinase 3, [Score=173, Expect=2e-46]} {Mouse: ENSMUSG00000035032, Nek11, NIMA (never in mitosis gene a)-related expressed kinase 11, [Score=169, Expect=1e-44]; ENSMUSG00000031478, Nek3, NIMA (never in mitosis gene a)-related expressed kinase 3, [Score=164, Expect=2e-43]} {Dmel: FBgn0029970, Nek2, [Score=120, Expect=5e-28]} {Celegans: WBGene00008956, nekl-3, Serine/threonine-protein kinase nekl-3, [Score=120, Expect=4e-30]} {Smed: dd_Smed_v6_9098_0_1, dd_Smed_v6_9098_0_1, [Score=175, Expect=4e-47]} {RNA1509_16354} {RNA1310_7781.1} {RNA815_3814.1}

Mlig455_045057 {REF} {Length: 5140} {Pfam: Protein kinase domain [PF00069.27, score=182.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=134.4]; Ankyrin repeats (3 copies) [PF12796.9, score=68.5]; Ankyrin repeats (many copies) [PF13637.8, score=56.3]; Ankyrin repeats (many copies) [PF13857.8, score=45.7]; Ankyrin repeat [PF13606.8, score=41.0]; Ankyrin repeat [PF00023.32, score=40.2]; Kinase-like [PF14531.8, score=38.6]} {Human: ENSG00000114670, NEK11, NIMA related kinase 11, [Score=179, Expect=4e-49]; ENSG00000136098, NEK3, NIMA related kinase 3, [Score=174, Expect=1e-46]} {Mouse: ENSMUSG00000035032, Nek11, NIMA (never in mitosis gene a)-related expressed kinase 11, [Score=170, Expect=7e-45]; ENSMUSG00000031478, Nek3, NIMA (never in mitosis gene a)-related expressed kinase 3, [Score=165, Expect=8e-44]} {Dmel: FBgn0029970, Nek2, [Score=120, Expect=6e-28]} {Celegans: WBGene00008956, nekl-3, Serine/threonine-protein kinase nekl-3, [Score=121, Expect=3e-30]} {Smed: dd_Smed_v6_9098_0_1, dd_Smed_v6_9098_0_1, [Score=175, Expect=4e-47]} {RNA1509_16354, RNA1509_24492} {RNA1310_7781.2, RNA1509_16354, RNA1509_24492} {RNA1509_16354, RNA1509_24492, RNA815_3814.1}
15. MligTC455_29164 899 18.73 Mlig455_006856

Neo: -

Age: Down-Up-Up

ANKRD42 3.313 0.808 0.729 - 0.820 0.956 - Mlig455_006856 {REF} {Length: 2038} {TRANSSPLICED} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=124.3]; Ankyrin repeats (3 copies) [PF12796.9, score=118.0]; Ankyrin repeats (many copies) [PF13857.8, score=106.6]; Ankyrin repeat [PF13606.8, score=85.3]; Ankyrin repeat [PF00023.32, score=69.9]} {Human: ENSG00000137494, ANKRD42, ankyrin repeat domain 42, [RH, Score=493, Expect=2e-170]} {Mouse: ENSMUSG00000041343, Ankrd42, ankyrin repeat domain 42, [RH, Score=491, Expect=1e-169]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=143, Expect=1e-35]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=125, Expect=4e-30]} {Smed: dd_Smed_v6_10615_0_1, dd_Smed_v6_10615_0_1, [RH, Score=621, Expect=0.0]} {RNA1509_29991} {RNA1310_12980.1} {RNA815_2353.1}
16. MligTC455_19084 292 6.08 Mlig455_021271

Neo: -

Age: -

3.128 - - 0.718 0.719 0.955 0.736 Mlig455_021271 {REF} {Length: 2744} {RNA1509_30062, RNA1509_39251} {RNA1310_9860, RNA1509_30062, RNA1509_39251} {RNA1509_30062, RNA1509_39251, RNA815_3403}
17. MligTC455_46254 1114 23.21 Mlig455_000448

Neo: -

Age: -

CASC1 2.699 - - - 0.899 0.969 0.831 Mlig455_000448 {REF} {Length: 3104} {Pfam: Cancer susceptibility candidate 1 N-terminus [PF15927.7, score=168.4]; Cancer susceptibility candidate 1 C-terminal [PF12366.10, score=29.2]} {Human: ENSG00000118307, CASC1, cancer susceptibility 1, [RH, Score=320, Expect=4e-98]} {Mouse: ENSMUSG00000043541, Casc1, cancer susceptibility candidate 1, [RH, Score=295, Expect=2e-88]} {Dmel: FBgn0030889, CG15373, [RH, Score=83.6, Expect=4e-16]} {Smed: dd_Smed_v6_11291_0_1, dd_Smed_v6_11291_0_1, [RH, Score=521, Expect=7e-175]} {RNA1509_1842} {RNA1310_6962.1, RNA1509_1842} {RNA1509_1842, RNA815_2139}
18. MligTC455_53773 707 14.74 Mlig455_002240

Neo: -

Age: logFC(26M/2M)=-0.336

ERICH3 2.664 - - - 0.898 0.950 0.816 Mlig455_002240 {REF} {Length: 6404} {Pfam: PLAT/LH2 domain [PF01477.25, score=233.3]; Domain of unknown function (DUF4590) [PF15257.8, score=138.1]; Embryo-specific protein 3, (ATS3) [PF06232.13, score=44.3]} {Human: ENSG00000178965, ERICH3, glutamate rich 3, [RH, Score=135, Expect=3e-31]} {Mouse: ENSMUSG00000078161, Erich3, glutamate rich 3, [RH, Score=127, Expect=1e-28]} {Celegans: WBGene00009201, F28C1.3, Protein phosphatase 1 regulatory subunit 37 homolog, [Score=59.3, Expect=2e-08]} {Smed: dd_Smed_v6_8627_0_1, dd_Smed_v6_8627_0_1, [Score=130, Expect=4e-30]} {RNA1509_1640} {RNA1310_3685} {RNA815_304.1}
19. MligTC455_30999 1203 25.06 Mlig455_024800

Neo: -

Age: -

MPEG1 2.648 - - 0.835 - 0.971 0.842 Mlig455_024800 {REF} {Length: 5471} {Pfam: MAC/Perforin domain [PF01823.21, score=73.6]} {Human: ENSG00000197629, MPEG1, macrophage expressed 1, [RH, Score=361, Expect=8e-111]} {Mouse: ENSMUSG00000046805, Mpeg1, macrophage expressed gene 1, [RH, Score=367, Expect=2e-113]} {Smed: dd_Smed_v6_983_0_1, dd_Smed_v6_983_0_1, [RH, Score=356, Expect=7e-110]} {RNA1509_45618, RNA1509_4699, RNA1509_52620, RNA1509_55031} {RNA1310_4591, RNA1509_45618, RNA1509_52620, RNA1509_55031} {RNA1509_45618, RNA1509_52620, RNA1509_55031, RNA815_1433.1}
20. MligTC455_53549 782 16.29 Mlig455_059223

Neo: -

Age: Down-Down-Up

SIDT1 2.642 - - 0.841 - 0.970 0.831 Mlig455_059223 {REF} {Length: 3659} {TRANSSPLICED} {Pfam: dsRNA-gated channel SID-1 [PF13965.8, score=293.6]} {Human: ENSG00000072858, SIDT1, SID1 transmembrane family member 1, [Score=169, Expect=2e-42]} {Mouse: ENSMUSG00000022696, Sidt1, SID1 transmembrane family, member 1, [Score=158, Expect=4e-39]; ENSMUSG00000034908, Sidt2, SID1 transmembrane family, member 2, [Score=154, Expect=7e-38]} {Celegans: WBGene00006477, chup-1, CHolesterol UPtake associated, [Score=118, Expect=6e-27]} {Smed: dd_Smed_v6_6063_0_2, dd_Smed_v6_6063_0_2, [Score=162, Expect=7e-41]} {RNA1509_26791} {RNA1310_31149.1} {RNA815_1905}
21. MligTC455_09824 279 5.81 Mlig455_060224

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.009

2.624 - - 0.817 - 0.953 0.854 Mlig455_060224 {REF} {Length: 2579} {RNA1509_40902} {RNA1310_14269} {RNA815_19496}
22. MligTC455_18663 961 20.02 Mlig455_026908, Mlig455_030748, Mlig455_030785

Neo: -

Age: -

Region-enriched R2: 1.212/0.02524

CEP290 2.622 - - - 0.968 0.893 0.761

Mlig455_026908 {REF} {Length: 8633} {Pfam: Coiled-coil region of centrosome protein CE290 [PF16574.7, score=98.4]; Autophagy protein 16 (ATG16) [PF08614.13, score=21.6]; Leucine zipper [PF15294.8, score=21.2]; SWI5-dependent HO expression protein 3 [PF17078.7, score=19.2]} {Human: ENSG00000198707, CEP290, centrosomal protein 290, [RH, Score=997, Expect=0.0]} {Mouse: ENSMUSG00000019971, Cep290, centrosomal protein 290, [RH, Score=985, Expect=0.0]} {Smed: dd_Smed_v6_7145_0_1, dd_Smed_v6_7145_0_1, [RH, Score=1252, Expect=0.0]} {RNA1509_1157, RNA1509_48500} {RNA1310_349, RNA1509_48500} {RNA1509_48500, RNA815_113}

Mlig455_030748 {REF} {Length: 8388} {TRANSSPLICED} {Pfam: Coiled-coil region of centrosome protein CE290 [PF16574.7, score=99.5]} {Human: ENSG00000198707, CEP290, centrosomal protein 290, [Score=620, Expect=0.0]} {Mouse: ENSMUSG00000019971, Cep290, centrosomal protein 290, [Score=525, Expect=9e-158]} {Smed: dd_Smed_v6_7145_0_1, dd_Smed_v6_7145_0_1, [Score=759, Expect=0.0]} {RNA1509_1157} {RNA1310_349} {RNA815_113}

Mlig455_030785 {REF} {Length: 8250} {TRANSSPLICED} {Pfam: Coiled-coil region of centrosome protein CE290 [PF16574.7, score=99.5]} {Human: ENSG00000198707, CEP290, centrosomal protein 290, [Score=620, Expect=0.0]} {Mouse: ENSMUSG00000019971, Cep290, centrosomal protein 290, [Score=525, Expect=9e-158]} {Smed: dd_Smed_v6_7145_0_1, dd_Smed_v6_7145_0_1, [Score=759, Expect=0.0]} {RNA1509_1157} {RNA1310_349} {RNA815_113}
23. MligTC455_47458 542 11.29 Mlig455_039325

Neo: -

Age: logFC(26M/2M)=-0.279

LRRC71 2.622 - - 0.828 - 0.950 0.844 Mlig455_039325 {REF} {Length: 2138} {TRANSSPLICED} {Pfam: Leucine Rich repeat [PF13516.8, score=71.0]; Leucine Rich repeats (2 copies) [PF12799.9, score=26.7]} {Human: ENSG00000160838, LRRC71, leucine rich repeat containing 71, [Score=184, Expect=4e-51]} {Mouse: ENSMUSG00000023084, Lrrc71, leucine rich repeat containing 71, [Score=181, Expect=3e-50]} {Smed: dd_Smed_v6_12043_0_2, dd_Smed_v6_12043_0_2, [RH, Score=225, Expect=3e-68]} {RNA1509_17632} {RNA1310_9823, RNA1509_17632} {RNA1509_17632, RNA815_14689.1}
24. MligTC455_25612 578 12.04 Mlig455_030061, Mlig455_030062

Neo: -

Age: logFC(26M/2M)=-0.274

CDH23, PCDHGB6 2.62 - 0.827 - 0.832 0.961 -

Mlig455_030061 {REF} {Length: 483} {Human: ENSG00000253305, PCDHGB6, protocadherin gamma subfamily B, 6, [Score=52.0, Expect=2e-08]} {Mouse: ENSMUSG00000103088, Pcdhgb6, protocadherin gamma subfamily B, 6, [Score=55.5, Expect=1e-09]} {Dmel: FBgn0037963, Cad87A, Cadherin 87A, [Score=47.8, Expect=3e-07]} {Celegans: WBGene00022103, cdh-12, CaDHerin family, [Score=52.8, Expect=6e-09]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [Score=73.9, Expect=2e-16]} {RNA1509_1684} {RNA1310_428} {RNA815_149.1}

Mlig455_030062 {REF} {Length: 6990} {Pfam: Cadherin domain [PF00028.19, score=457.2]; Cadherin-like [PF08266.14, score=43.6]; RET Cadherin like domain 1 [PF17756.3, score=28.2]} {Human: ENSG00000107736, CDH23, cadherin related 23, [Score=500, Expect=7e-144]} {Mouse: ENSMUSG00000012819, Cdh23, cadherin 23 (otocadherin), [Score=500, Expect=6e-144]} {Dmel: FBgn0038247, Cad88C, Cadherin 88C, [RH, Score=631, Expect=0.0]} {Celegans: WBGene00017576, cdh-8, CaDHerin family, [RH, Score=209, Expect=4e-54]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [RH, Score=746, Expect=0.0]} {RNA1509_1684, RNA1509_44410} {RNA1310_428, RNA1509_1684, RNA1509_44410} {RNA1509_1684, RNA1509_44410, RNA815_149.1}
25. MligTC455_47670 709 14.77 Mlig455_064585

Neo: -

Age: -

Region-enriched R2: 1.616/0.00648

2.611 - - 0.950 0.795 0.866 - Mlig455_064585 {REF} {Length: 1016} {RNA1509_15853} {RNA1310_37053} {RNA815_24569.1}
26. MligTC455_51932 416 8.66 Mlig455_024400

Neo: -

Age: -

CBS 2.61 - - 0.962 0.798 - 0.850 Mlig455_024400 {REF} {Length: 2381} {TRANSSPLICED} {Pfam: Pyridoxal-phosphate dependent enzyme [PF00291.27, score=210.9]; CBS domain [PF00571.30, score=47.7]} {Human: ENSG00000160200, CBS, cystathionine-beta-synthase, [RH, Score=615, Expect=0.0]; ENSG00000274276, CBSL, cystathionine-beta-synthase like, [RH, Score=615, Expect=0.0]} {Mouse: ENSMUSG00000024039, Cbs, cystathionine beta-synthase, [RH, Score=619, Expect=0.0]} {Dmel: FBgn0031148, Cbs, centrosomin's beautiful sister, [RH, Score=444, Expect=1e-151]} {Celegans: WBGene00013866, cbs-1, Cystathionine Beta-Synthase, [RH, Score=355, Expect=1e-114]} {Smed: dd_Smed_v6_1585_0_1, dd_Smed_v6_1585_0_1, [RH, Score=641, Expect=0.0]} {RNA1509_36721, RNA1509_49877} {RNA1310_10809, RNA1509_36721, RNA1509_49877} {RNA1509_36721, RNA1509_49877, RNA815_3797.1}
27. MligTC455_28168 822 17.12 Mlig455_023828

Neo: -

Age: -

2.606 - - 0.896 0.759 0.951 - Mlig455_023828 {REF} {Length: 3967} {Smed: dd_Smed_v6_6429_0_1, dd_Smed_v6_6429_0_1, [Score=99.0, Expect=5e-22]} {RNA1509_9848} {RNA1310_8221} {RNA815_6368.1}
28. MligTC455_47669 793 16.52 Mlig455_040755

Neo: -

Age: -

Region-enriched R2: 1.568/0.00407

2.6 - - 0.970 0.766 0.864 - Mlig455_040755 {REF} {Length: 8844} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=33.0]; Ankyrin repeats (many copies) [PF13637.8, score=21.8]} {RNA1509_15853} {RNA1310_18916} {RNA815_34185}
29. MligTC455_47383 2319 48.32 Mlig455_049031, Mlig455_063739

Neo: -

Age: logFC(26M/2M)=1.164

2.598 - - 0.849 0.789 0.960 -

Mlig455_049031 {REF} {Length: 1477} {RNA1509_16827} {RNA1310_19392.1} {RNA815_20667}

Mlig455_063739 {REF} {Length: 5644} {RNA1509_9711} {RNA1310_19392.1} {RNA815_20667}
30. MligTC455_30801 483 10.05 Mlig455_027631, Mlig455_027642

Neo: -

Age: Up-Down-Down

Region-enriched R4: 2.277/0.03108

TRPM7 2.596 - - 0.876 - 0.956 0.764

Mlig455_027631 {REF} {Length: 3904} {Pfam: Ion transport protein [PF00520.33, score=35.0]} {Human: ENSG00000092439, TRPM7, transient receptor potential cation channel subfamily M member 7, [Score=79.0, Expect=3e-14]} {Mouse: ENSMUSG00000027365, Trpm7, transient receptor potential cation channel, subfamily M, member 7, [Score=73.9, Expect=5e-13]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=81.6, Expect=2e-15]} {Celegans: WBGene00001651, gon-2, Transient receptor potential channel, [Score=70.5, Expect=3e-12]} {Smed: dd_Smed_v6_26251_0_1, dd_Smed_v6_26251_0_1, [Score=100, Expect=1e-21]} {RNA1509_8759} {RNA1310_4330.3, RNA1509_8759} {RNA1509_8759, RNA815_1383.1}

Mlig455_027642 {REF} {Length: 4185} {Pfam: Ion transport protein [PF00520.33, score=35.0]} {Human: ENSG00000092439, TRPM7, transient receptor potential cation channel subfamily M member 7, [Score=76.3, Expect=1e-13]} {Mouse: ENSMUSG00000027365, Trpm7, transient receptor potential cation channel, subfamily M, member 7, [Score=71.6, Expect=3e-12]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=81.3, Expect=2e-15]} {Celegans: WBGene00001651, gon-2, Transient receptor potential channel, [Score=70.5, Expect=3e-12]} {Smed: dd_Smed_v6_26251_0_1, dd_Smed_v6_26251_0_1, [Score=100, Expect=1e-21]} {RNA1509_8759} {RNA1310_3171.2} {RNA815_1383.1}
31. MligTC455_20201 1626 33.88 Mlig455_025333

Neo: -

Age: logFC(26M/2M)=-0.331

TRPA1 2.577 - 0.777 - 0.850 0.950 - Mlig455_025333 {REF} {Length: 5343} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=283.4]; Ankyrin repeat [PF00023.32, score=234.0]; Ankyrin repeats (many copies) [PF13637.8, score=227.4]; Ankyrin repeat [PF13606.8, score=217.2]; Ankyrin repeats (many copies) [PF13857.8, score=212.6]; Ion transport protein [PF00520.33, score=53.3]} {Human: ENSG00000104321, TRPA1, transient receptor potential cation channel subfamily A member 1, [Score=368, Expect=5e-107]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=363, Expect=2e-105]} {Dmel: FBgn0035934, TrpA1, Transient receptor potential cation channel A1, [Score=325, Expect=8e-92]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=489, Expect=2e-150]} {Smed: dd_Smed_v6_6201_0_1, dd_Smed_v6_6201_0_1, [RH, Score=754, Expect=0.0]} {RNA1509_20092} {RNA1310_1173, RNA1509_20092} {RNA1509_20092, RNA815_336}
32. MligTC455_39608 6604 137.59 Mlig455_023921, Mlig455_046482

Neo: -

Age: -

APP 2.552 - - 0.733 0.849 0.970 -

Mlig455_023921 {REF} {Length: 3702} {TRANSSPLICED} {Pfam: Amyloid A4 N-terminal heparin-binding [PF02177.18, score=48.7]; E2 domain of amyloid precursor protein [PF12925.9, score=43.8]; Beta-amyloid precursor protein C-terminus [PF10515.11, score=40.8]; Copper-binding of amyloid precursor, CuBD [PF12924.9, score=39.1]} {Human: ENSG00000142192, APP, amyloid beta precursor protein, [Score=84.3, Expect=3e-16]} {Mouse: ENSMUSG00000022892, App, amyloid beta (A4) precursor protein, [Score=84.0, Expect=3e-16]} {Dmel: FBgn0000108, Appl, beta amyloid protein precursor-like, [Score=85.9, Expect=6e-17]} {Celegans: WBGene00000149, apl-1, Beta-amyloid-like protein, [RH, Score=101, Expect=4e-22]} {Smed: dd_Smed_v6_2561_0_1, dd_Smed_v6_2561_0_1, [RH, Score=134, Expect=7e-33]} {RNA1509_11651, RNA1509_19546, RNA1509_2244, RNA1509_31480, RNA1509_4900} {RNA1310_3149.1, RNA1509_11651, RNA1509_19546, RNA1509_2244, RNA1509_31480, RNA1509_4900} {RNA1509_11651, RNA1509_19546, RNA1509_2244, RNA1509_31480, RNA1509_4900, RNA815_958.1}

Mlig455_046482 {REF} {Length: 3710} {TRANSSPLICED} {Pfam: Amyloid A4 N-terminal heparin-binding [PF02177.18, score=47.8]; E2 domain of amyloid precursor protein [PF12925.9, score=43.1]; Beta-amyloid precursor protein C-terminus [PF10515.11, score=40.8]; Copper-binding of amyloid precursor, CuBD [PF12924.9, score=39.2]} {Human: ENSG00000142192, APP, amyloid beta precursor protein, [Score=84.7, Expect=2e-16]} {Mouse: ENSMUSG00000022892, App, amyloid beta (A4) precursor protein, [Score=84.3, Expect=2e-16]} {Dmel: FBgn0000108, Appl, beta amyloid protein precursor-like, [Score=85.5, Expect=9e-17]} {Celegans: WBGene00000149, apl-1, Beta-amyloid-like protein, [RH, Score=103, Expect=9e-23]} {Smed: dd_Smed_v6_2561_0_1, dd_Smed_v6_2561_0_1, [RH, Score=138, Expect=3e-34]} {RNA1509_11651, RNA1509_35488} {RNA1310_3149.1, RNA1509_35488} {RNA1509_35488, RNA815_958.1}
33. MligTC455_43063 5711 118.98 Mlig455_008727, Mlig455_063588, Mlig455_063597

Neo: -

Age: logFC(26M/2M)=-0.428

Region-enriched R8: 1.085/0.01787

GGT1 2.54 - 0.790 - 0.795 0.955 -

Mlig455_008727 {REF} {Length: 2577} {Pfam: Gamma-glutamyltranspeptidase [PF01019.23, score=528.5]} {Human: ENSG00000100031, GGT1, gamma-glutamyltransferase 1, [RH, Score=419, Expect=8e-139]} {Mouse: ENSMUSG00000006345, Ggt1, gamma-glutamyltransferase 1, [RH, Score=392, Expect=2e-128]} {Dmel: FBgn0025837, CG17636, [RH, Score=352, Expect=7e-113]} {Celegans: WBGene00016906, C53D5.5, [RH, Score=387, Expect=6e-126]} {Smed: dd_Smed_v6_4591_0_1, dd_Smed_v6_4591_0_1, [RH, Score=443, Expect=7e-148]} {RNA1509_10553, RNA1509_2471, RNA1509_29196} {RNA1310_8769, RNA1509_10553, RNA1509_29196} {RNA1509_10553, RNA1509_29196, RNA815_2837}

Mlig455_063588 {REF} {Length: 2595} {Pfam: Gamma-glutamyltranspeptidase [PF01019.23, score=502.5]} {Human: ENSG00000100031, GGT1, gamma-glutamyltransferase 1, [RH, Score=409, Expect=1e-136]} {Mouse: ENSMUSG00000006345, Ggt1, gamma-glutamyltransferase 1, [Score=381, Expect=5e-126]} {Dmel: FBgn0025837, CG17636, [RH, Score=348, Expect=4e-113]} {Celegans: WBGene00016906, C53D5.5, [Score=357, Expect=3e-116]} {Smed: dd_Smed_v6_4591_0_2, dd_Smed_v6_4591_0_2, [RH, Score=402, Expect=5e-134]} {RNA1509_2471} {RNA1310_8769} {RNA815_2837}

Mlig455_063597 {REF} {Length: 2607} {Pfam: Gamma-glutamyltranspeptidase [PF01019.23, score=527.1]} {Human: ENSG00000100031, GGT1, gamma-glutamyltransferase 1, [RH, Score=417, Expect=4e-139]} {Mouse: ENSMUSG00000006345, Ggt1, gamma-glutamyltransferase 1, [Score=389, Expect=3e-128]} {Dmel: FBgn0025837, CG17636, [RH, Score=351, Expect=2e-113]} {Celegans: WBGene00016906, C53D5.5, [RH, Score=386, Expect=3e-126]} {Smed: dd_Smed_v6_4591_0_1, dd_Smed_v6_4591_0_1, [RH, Score=443, Expect=4e-149]} {RNA1509_2471, RNA1509_44409} {RNA1310_8769, RNA1509_44409} {RNA1509_44409, RNA815_2837}
34. MligTC455_26415 2005 41.78 Mlig455_001522, Mlig455_021111

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.344

Region-specific R2: 2.002

Region-enriched R8: 1.590/0.00032
Region-enriched R2: 1.465/0.00020

2.514 - 0.776 - 0.783 0.955 -

Mlig455_001522 {REF} {Length: 3040} {Pfam: Family of unknown function (DUF5580) [PF17743.3, score=85.0]} {Smed: dd_Smed_v6_9326_0_1, dd_Smed_v6_9326_0_1, [Score=167, Expect=3e-44]} {RNA1509_39579} {RNA1310_4999.1} {RNA815_4435}

Mlig455_021111 {REF} {Length: 2843} {Pfam: Family of unknown function (DUF5580) [PF17743.3, score=85.7]} {Smed: dd_Smed_v6_9326_0_1, dd_Smed_v6_9326_0_1, [Score=167, Expect=1e-44]} {RNA1509_4141} {RNA1310_6622.2} {RNA815_8857}
35. MligTC455_49179 1230 25.62 Mlig455_000575, Mlig455_030372

Neo: -

Age: Down-Up-Down

GRIK1 2.507 - - 0.786 0.761 0.960 -

Mlig455_000575 {REF} {Length: 3002} {Pfam: Ligand-gated ion channel [PF00060.28, score=56.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=22.4]; Receptor family ligand binding region [PF01094.30, score=21.2]} {Human: ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=76.6, Expect=1e-13]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=73.6, Expect=1e-12]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=73.9, Expect=6e-13]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=73.2, Expect=1e-12]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=66.2, Expect=9e-11]} {Smed: dd_Smed_v6_10048_0_1, dd_Smed_v6_10048_0_1, [Score=71.2, Expect=1e-12]} {RNA1509_5131} {RNA1310_3885, RNA1509_5131} {RNA1509_5131, RNA815_1090.1}

Mlig455_030372 {REF} {Length: 3002} {Pfam: Ligand-gated ion channel [PF00060.28, score=56.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=22.5]; Receptor family ligand binding region [PF01094.30, score=21.4]} {Human: ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=76.6, Expect=1e-13]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=73.6, Expect=1e-12]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=73.9, Expect=6e-13]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=73.2, Expect=1e-12]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=65.5, Expect=1e-10]} {Smed: dd_Smed_v6_10048_0_1, dd_Smed_v6_10048_0_1, [Score=71.6, Expect=1e-12]} {RNA1509_5131} {RNA1310_3885} {RNA815_1090.1}
36. MligTC455_35890 1563 32.56 Mlig455_047529, Mlig455_047538, Mlig455_059662

Neo: -

Age: -

IFT80 2.493 - - 0.818 0.954 0.721 -

Mlig455_047529 {REF} {Length: 2724} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=55.0]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=38.4]} {Human: ENSG00000068885, IFT80, intraflagellar transport 80, [RH, Score=871, Expect=0.0]} {Mouse: ENSMUSG00000027778, Ift80, intraflagellar transport 80, [RH, Score=868, Expect=0.0]} {Dmel: FBgn0032891, Oseg5, Outer segment 5, [RH, Score=447, Expect=7e-146]} {Celegans: WBGene00000484, che-2, CHE-2 protein, [RH, Score=581, Expect=0.0]} {Smed: dd_Smed_v6_9110_0_1, dd_Smed_v6_9110_0_1, [RH, Score=793, Expect=0.0]} {RNA1509_7485} {RNA1310_7061, RNA1509_7485} {RNA1509_7485, RNA815_2221}

Mlig455_047538 {REF} {Length: 2547} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=52.2]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=35.7]} {Human: ENSG00000068885, IFT80, intraflagellar transport 80, [Score=703, Expect=0.0]} {Mouse: ENSMUSG00000027778, Ift80, intraflagellar transport 80, [Score=703, Expect=0.0]} {Dmel: FBgn0032891, Oseg5, Outer segment 5, [Score=358, Expect=2e-113]} {Celegans: WBGene00000484, che-2, CHE-2 protein, [Score=451, Expect=3e-149]} {Smed: dd_Smed_v6_9110_0_1, dd_Smed_v6_9110_0_1, [Score=620, Expect=0.0]} {RNA1509_7485} {RNA1310_7061} {RNA815_2221}

Mlig455_059662 {REF} {Length: 2718} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=54.8]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=38.1]} {Human: ENSG00000068885, IFT80, intraflagellar transport 80, [RH, Score=871, Expect=0.0]} {Mouse: ENSMUSG00000027778, Ift80, intraflagellar transport 80, [RH, Score=869, Expect=0.0]} {Dmel: FBgn0032891, Oseg5, Outer segment 5, [RH, Score=448, Expect=2e-146]} {Celegans: WBGene00000484, che-2, CHE-2 protein, [RH, Score=581, Expect=0.0]} {Smed: dd_Smed_v6_9110_0_1, dd_Smed_v6_9110_0_1, [RH, Score=794, Expect=0.0]} {RNA1509_7485} {RNA1310_7061} {RNA815_2221}
37. MligTC455_48259 676 14.08 Mlig455_020900

Neo: -

Age: -

CALM2 2.493 - - 0.955 0.828 0.710 - Mlig455_020900 {REF} {Length: 1620} {Pfam: EF hand [PF00036.34, score=97.7]; EF-hand domain pair [PF13499.8, score=83.8]; EF hand [PF13202.8, score=77.0]; EF-hand domain [PF13405.8, score=71.6]; EF-hand domain pair [PF13833.8, score=70.2]; EF-hand domain [PF14658.8, score=31.0]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=25.2]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=23.5]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=104, Expect=2e-27]; ENSG00000198668, CALM1, calmodulin 1, [Score=103, Expect=9e-28]; ENSG00000160014, CALM3, calmodulin 3, [Score=103, Expect=1e-27]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=105, Expect=8e-28]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=103, Expect=7e-28]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=103, Expect=7e-28]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=100, Expect=2e-26]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=103, Expect=1e-27]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=103, Expect=8e-28]} {Smed: dd_Smed_v6_11942_0_1, dd_Smed_v6_11942_0_1, [Score=104, Expect=3e-28]} {RNA1509_42541, RNA1509_8417} {RNA1310_18928.1, RNA1509_42541, RNA1509_8417} {RNA1509_42541, RNA1509_8417, RNA815_13201}
38. MligTC455_50685 443 9.22 Mlig455_008930

Neo: -

Age: Up-Down-Down

LRRK2 2.47 - - 0.786 0.733 0.951 - Mlig455_008930 {REF} {Length: 12042} {TRANSSPLICED} {Pfam: C-terminal of Roc, COR, domain [PF16095.7, score=151.5]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=75.1]; TIR domain [PF13676.8, score=67.0]; Ras family [PF00071.24, score=44.4]; Leucine rich repeat [PF13855.8, score=39.4]; Leucine Rich repeats (2 copies) [PF12799.9, score=24.7]} {Human: ENSG00000188906, LRRK2, leucine rich repeat kinase 2, [Score=158, Expect=1e-37]} {Mouse: ENSMUSG00000036273, Lrrk2, leucine-rich repeat kinase 2, [Score=161, Expect=9e-39]} {Dmel: FBgn0038816, Lrrk, Leucine-rich repeat kinase, [Score=146, Expect=3e-34]} {Celegans: WBGene00003068, lrk-1, Leucine-rich repeat serine/threonine-protein kinase 1, [Score=122, Expect=5e-27]} {Smed: dd_Smed_v6_12105_0_1, dd_Smed_v6_12105_0_1, [Score=714, Expect=0.0]} {RNA1509_2407, RNA1509_24338, RNA1509_49350} {RNA1310_77.1, RNA1509_2407, RNA1509_24338, RNA1509_49350} {RNA1509_2407, RNA1509_24338, RNA1509_49350, RNA815_489}
39. MligTC455_21637 2229 46.44 Mlig455_052609, Mlig455_052656

Neo: -

Age: -

Region-enriched R2: 1.063/0.02338

SLC6A5 2.41 - - 0.708 0.744 0.958 -

Mlig455_052609 {REF} {Length: 3232} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=607.1]} {Human: ENSG00000165970, SLC6A5, solute carrier family 6 member 5, [Score=493, Expect=9e-164]} {Mouse: ENSMUSG00000039728, Slc6a5, solute carrier family 6 (neurotransmitter transporter, glycine), member 5, [Score=496, Expect=2e-165]} {Dmel: FBgn0034911, CG5549, [Score=500, Expect=1e-162]} {Celegans: WBGene00004905, snf-6, Sodium-dependent acetylcholine transporter, [RH, Score=383, Expect=6e-123]} {Smed: dd_Smed_v6_10458_0_1, dd_Smed_v6_10458_0_1, [Score=458, Expect=3e-152]} {RNA1509_11553} {RNA1310_4707.1} {RNA815_1349.1}

Mlig455_052656 {REF} {Length: 3033} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=472.2]} {Human: ENSG00000165970, SLC6A5, solute carrier family 6 member 5, [Score=387, Expect=2e-124]} {Mouse: ENSMUSG00000039728, Slc6a5, solute carrier family 6 (neurotransmitter transporter, glycine), member 5, [Score=388, Expect=6e-125]} {Dmel: FBgn0034911, CG5549, [Score=390, Expect=3e-122]} {Celegans: WBGene00004905, snf-6, Sodium-dependent acetylcholine transporter, [Score=291, Expect=6e-89]} {Smed: dd_Smed_v6_10458_0_1, dd_Smed_v6_10458_0_1, [Score=353, Expect=5e-113]} {RNA1509_26562} {RNA1310_4707.1} {RNA815_1349.1}
40. MligTC455_52893 350 7.29 Mlig455_055901

Neo: -

Age: -

ANK3 2.406 - - 0.716 0.727 0.963 - Mlig455_055901 {REF} {Length: 2748} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=83.0]; Ankyrin repeats (many copies) [PF13857.8, score=78.9]; Ankyrin repeats (many copies) [PF13637.8, score=77.7]; Ankyrin repeat [PF13606.8, score=54.6]; Ankyrin repeat [PF00023.32, score=51.9]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=59.7, Expect=2e-08]} {Mouse: ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=57.0, Expect=7e-08]; ENSMUSG00000033701, Acbd6, acyl-Coenzyme A binding domain containing 6, [Score=54.3, Expect=1e-07]} {Dmel: FBgn0040372, G9a, [Score=64.3, Expect=3e-10]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=50.1, Expect=5e-06]} {Smed: dd_Smed_v6_9418_0_1, dd_Smed_v6_9418_0_1, [RH, Score=165, Expect=4e-44]} {RNA1509_13574, RNA1509_25185} {RNA1310_7698, RNA1509_13574, RNA1509_25185} {RNA1509_13574, RNA1509_25185, RNA815_7052}
41. MligTC455_32487 595 12.39 Mlig455_017119

Neo: -

Age: logFC(26M/2M)=-0.391

2.395 - - 0.705 - 0.976 0.714 Mlig455_017119 {REF} {Length: 2322} {RNA1509_10657} {RNA1310_11689, RNA1509_10657} {RNA1509_10657, RNA815_5499}
42. MligTC455_33343 459 9.56 Mlig455_063303

Neo: -

Age: -

Region-enriched R2: 1.600/0.01675

ITPR1 1.879 - - - 0.913 0.966 - Mlig455_063303 {REF} {Length: 3962} {Pfam: RyR and IP3R Homology associated [PF08454.13, score=68.3]; Ion transport protein [PF00520.33, score=28.7]} {Human: ENSG00000150995, ITPR1, inositol 1,4,5-trisphosphate receptor type 1, [Score=166, Expect=6e-41]} {Mouse: ENSMUSG00000030102, Itpr1, inositol 1,4,5-trisphosphate receptor 1, [Score=182, Expect=7e-46]} {Dmel: FBgn0010051, Itp-r83A, Inositol 1,4,5,-tris-phosphate receptor, [Score=179, Expect=4e-45]} {Celegans: WBGene00002173, itr-1, Inositol 1,4,5-trisphosphate receptor itr-1, [Score=155, Expect=5e-38]} {Smed: dd_Smed_v6_3814_1_1, dd_Smed_v6_3814_1_1, [Score=1044, Expect=0.0]} {RNA1509_30811} {RNA1310_939} {RNA815_220}
43. MligTC455_15700 381 7.93 Mlig455_029700

Neo: -

Age: -

NEK9 1.868 - - - - 0.916 0.952 Mlig455_029700 {REF} {Length: 3273} {Pfam: Protein kinase domain [PF00069.27, score=196.8]; Regulator of chromosome condensation (RCC1) repeat [PF00415.20, score=167.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=136.5]; Regulator of chromosome condensation (RCC1) repeat [PF13540.8, score=78.8]; Fungal protein kinase [PF17667.3, score=20.1]} {Human: ENSG00000119638, NEK9, NIMA related kinase 9, [RH, Score=743, Expect=0.0]} {Mouse: ENSMUSG00000034290, Nek9, NIMA (never in mitosis gene a)-related expressed kinase 9, [RH, Score=724, Expect=0.0]} {Dmel: FBgn0045980, niki, nimA-like kinase, [Score=308, Expect=2e-91]} {Celegans: WBGene00021461, nekl-1, NEK (NEver in mitosis Kinase) Like, [Score=355, Expect=3e-108]} {Smed: dd_Smed_v6_8692_0_1, dd_Smed_v6_8692_0_1, [RH, Score=576, Expect=0.0]} {RNA1509_4066} {RNA1310_4454, RNA1509_4066} {RNA1509_4066, RNA815_1625}
44. MligTC455_16002 752 15.67 Mlig455_062545

Neo: -

Age: -

TTC16 1.862 - - 0.896 - 0.966 - Mlig455_062545 {REF} {Length: 2280} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF07719.19, score=82.7]; Tetratricopeptide repeat [PF00515.30, score=64.9]; TPR repeat [PF13414.8, score=58.1]; Tetratricopeptide repeat [PF13432.8, score=57.0]; Tetratricopeptide repeat [PF13181.8, score=56.4]; Tetratricopeptide repeat [PF13428.8, score=54.2]; Tetratricopeptide repeat [PF14559.8, score=42.2]; Tetratricopeptide repeat [PF13424.8, score=41.4]; Tetratricopeptide repeat [PF13371.8, score=32.2]; Tetratricopeptide repeat [PF13176.8, score=31.2]; Tetratricopeptide repeat [PF13431.8, score=24.0]; NMDA receptor-regulated protein 1 [PF12569.10, score=23.7]; Tetratricopeptide repeat [PF13174.8, score=21.3]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=19.2]} {Human: ENSG00000167094, TTC16, tetratricopeptide repeat domain 16, [RH, Score=291, Expect=3e-86]} {Mouse: ENSMUSG00000039021, Ttc16, tetratricopeptide repeat domain 16, [RH, Score=295, Expect=9e-89]} {Celegans: WBGene00000500, chn-1, C-term of Hsp70-iNteracting protein (CHIP family); Hsp70-interacting protein, [Score=50.8, Expect=1e-06]} {Smed: dd_Smed_v6_11894_0_1, dd_Smed_v6_11894_0_1, [RH, Score=447, Expect=1e-147]} {RNA1509_9009} {RNA1310_10645.1, RNA1509_9009} {RNA1509_9009, RNA815_3627}
45. MligTC455_51758 3507 73.06 Mlig455_034288, Mlig455_069010

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.314

TTC25 1.855 - - - 0.887 0.968 -

Mlig455_034288 {REF} {Length: 2046} {Pfam: Tetratricopeptide repeat [PF07719.19, score=75.1]; Tetratricopeptide repeat [PF13424.8, score=58.6]; Tetratricopeptide repeat [PF00515.30, score=57.0]; Tetratricopeptide repeat [PF13181.8, score=42.5]; Tetratricopeptide repeat [PF13428.8, score=37.4]; Tetratricopeptide repeat [PF13432.8, score=36.7]; Tetratricopeptide repeat [PF14559.8, score=33.8]; TPR repeat [PF13414.8, score=29.6]; Tetratricopeptide repeat [PF13176.8, score=26.9]; Anaphase-promoting complex, cyclosome, subunit 3 [PF12895.9, score=25.5]; Tetratricopeptide repeat [PF13371.8, score=25.3]; Domain of Unknown Function (DUF3856) [PF12968.9, score=22.7]; Tetratricopeptide repeat [PF13431.8, score=21.6]} {Human: ENSG00000204815, TTC25, tetratricopeptide repeat domain 25, [RH, Score=404, Expect=2e-133]} {Mouse: ENSMUSG00000006784, Ttc25, tetratricopeptide repeat domain 25, [RH, Score=423, Expect=3e-141]} {Dmel: FBgn0034692, CG13502, [RH, Score=151, Expect=9e-42]} {Smed: dd_Smed_v6_3933_0_1, dd_Smed_v6_3933_0_1, [RH, Score=530, Expect=0.0]} {RNA1509_32935} {RNA1310_11497} {RNA815_2107.1}

Mlig455_069010 {REF} {Length: 2043} {Pfam: Tetratricopeptide repeat [PF07719.19, score=74.3]; Tetratricopeptide repeat [PF00515.30, score=59.7]; Tetratricopeptide repeat [PF13424.8, score=54.7]; Tetratricopeptide repeat [PF13181.8, score=43.2]; Tetratricopeptide repeat [PF13432.8, score=38.5]; Tetratricopeptide repeat [PF13428.8, score=37.2]; Tetratricopeptide repeat [PF14559.8, score=35.1]; TPR repeat [PF13414.8, score=27.9]; Tetratricopeptide repeat [PF13176.8, score=27.4]; Anaphase-promoting complex, cyclosome, subunit 3 [PF12895.9, score=26.1]; Tetratricopeptide repeat [PF13371.8, score=24.1]; Domain of Unknown Function (DUF3856) [PF12968.9, score=22.4]; Tetratricopeptide repeat [PF13431.8, score=22.2]} {Human: ENSG00000204815, TTC25, tetratricopeptide repeat domain 25, [RH, Score=402, Expect=1e-132]} {Mouse: ENSMUSG00000006784, Ttc25, tetratricopeptide repeat domain 25, [RH, Score=421, Expect=2e-140]} {Dmel: FBgn0034692, CG13502, [RH, Score=150, Expect=3e-41]} {Smed: dd_Smed_v6_3933_0_1, dd_Smed_v6_3933_0_1, [RH, Score=525, Expect=0.0]} {RNA1509_32935, RNA1509_59660} {RNA1310_11497, RNA1509_59660} {RNA1509_59660, RNA815_2107.1}
46. MligTC455_42557 354 7.38 Mlig455_026024

Neo: -

Age: -

1.842 - - 0.884 - 0.958 - Mlig455_026024 {REF} {Length: 1890} {TRANSSPLICED} {RNA1509_23566, RNA1509_54428, RNA1509_56722} {RNA1310_23201.2, RNA1509_23566, RNA1509_54428, RNA1509_56722} {RNA1509_23566, RNA1509_54428, RNA1509_56722, RNA815_9453.1}
47. MligTC455_18720 595 12.4 Mlig455_041810

Neo: -

Age: logFC(26M/2M)=-0.320

ANKUB1 1.829 - - 0.874 - 0.955 - Mlig455_041810 {REF} {Length: 2454} {Pfam: Ubiquitin family [PF00240.25, score=36.0]} {Human: ENSG00000206199, ANKUB1, ankyrin repeat and ubiquitin domain containing 1, [RH, Score=258, Expect=8e-78]} {Mouse: ENSMUSG00000074591, Ankub1, ankrin repeat and ubiquitin domain containing 1, [RH, Score=258, Expect=5e-78]} {Smed: dd_Smed_v6_9027_0_1, dd_Smed_v6_9027_0_1, [RH, Score=508, Expect=2e-173]} {RNA1509_23349, RNA1509_30870, RNA1509_7686} {RNA1310_10366.1, RNA1509_23349, RNA1509_30870, RNA1509_7686} {RNA1509_23349, RNA1509_30870, RNA1509_7686, RNA815_3711.1}
48. MligTC455_33293 190 3.95 Mlig455_039617, Mlig455_051433

Neo: -

Age: logFC(26M/2M)=-0.344

CERKL 1.814 - - - - 0.967 0.847

Mlig455_039617 {REF} {Length: 1308} {RNA1509_27178} {RNA1310_5866.1} {RNA815_1765}

Mlig455_051433 {REF} {Length: 4899} {TRANSSPLICED} {Pfam: Diacylglycerol kinase catalytic domain [PF00781.26, score=53.4]; Ceramide kinase C-terminal domain [PF19280.1, score=36.3]} {Human: ENSG00000188452, CERKL, ceramide kinase like, [Score=109, Expect=3e-24]} {Mouse: ENSMUSG00000075256, Cerkl, ceramide kinase-like, [Score=96.7, Expect=2e-20]} {Dmel: FBgn0037315, Cerk, Ceramide kinase, [Score=97.4, Expect=2e-20]} {Smed: dd_Smed_v6_9323_0_1, dd_Smed_v6_9323_0_1, [Score=120, Expect=2e-28]} {RNA1509_12345, RNA1509_27178} {RNA1310_5866.1, RNA1509_12345, RNA1509_27178} {RNA1509_12345, RNA1509_27178, RNA815_1765}
49. MligTC455_43767 1310 27.29 Mlig455_048807

Neo: -

Age: Down-Down-Up

EFHB 1.813 - - - 0.863 0.950 - Mlig455_048807 {REF} {Length: 2201} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=45.4]; EF hand [PF00036.34, score=42.2]; EF-hand domain [PF13405.8, score=40.2]; Family of unknown function (DUF5580) [PF17743.3, score=32.2]; EF hand [PF13202.8, score=31.1]; EF-hand domain pair [PF13833.8, score=18.8]} {Human: ENSG00000163576, EFHB, EF-hand domain family member B, [RH, Score=386, Expect=1e-125]} {Mouse: ENSMUSG00000023931, Efhb, EF hand domain family, member B, [RH, Score=359, Expect=7e-114]} {Dmel: FBgn0004910, Eip63F-1, Ecdysone-induced protein 63F 1, [Score=53.1, Expect=6e-08]} {Celegans: WBGene00000286, cal-2, CALmodulin related genes; Calmodulin-like protein, [Score=52.8, Expect=7e-08]} {Smed: dd_Smed_v6_11909_0_1, dd_Smed_v6_11909_0_1, [RH, Score=351, Expect=3e-114]} {RNA1509_2205} {RNA1310_7693} {RNA815_3913}
50. MligTC455_16992 25 0.51 Mlig455_058183

Neo: -

Age: -

1.807 - - 0.855 - 0.952 - Mlig455_058183 {REF} {Length: 3198} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=123.5]; WSC domain [PF01822.21, score=40.6]} {Celegans: WBGene00003168, mec-4, Degenerin mec-4, [Score=59.7, Expect=7e-09]} {Smed: dd_Smed_v6_21491_0_1, dd_Smed_v6_21491_0_1, [Score=58.9, Expect=8e-09]} {RNA1509_20328} {RNA1310_3478} {RNA815_19382.1}
51. MligTC455_20230 1282 26.71 Mlig455_003493, Mlig455_015562

Neo: -

Age: logFC(26M/2M)=-0.236

FAM227A, FAM227B 1.805 - - - 0.831 0.974 -

Mlig455_003493 {REF} {Length: 2231} {TRANSSPLICED} {Pfam: Protein of unknown function [PF14922.8, score=146.0]} {Human: ENSG00000184949, FAM227A, family with sequence similarity 227 member A, [Score=111, Expect=2e-25]} {Mouse: ENSMUSG00000042564, Fam227a, family with sequence similarity 227, member A, [RH, Score=96.7, Expect=8e-21]; ENSMUSG00000027209, Fam227b, family with sequence similarity 227, member B, [RH, Score=93.6, Expect=6e-20]} {Smed: dd_Smed_v6_15102_0_3, dd_Smed_v6_15102_0_3, [Score=157, Expect=3e-42]} {RNA1509_44428} {RNA1310_6983.2} {RNA815_5876}

Mlig455_015562 {REF} {Length: 2171} {TRANSSPLICED} {Pfam: Protein of unknown function [PF14922.8, score=146.7]} {Human: ENSG00000166262, FAM227B, family with sequence similarity 227 member B, [RH, Score=107, Expect=2e-24]} {Mouse: ENSMUSG00000027209, Fam227b, family with sequence similarity 227, member B, [RH, Score=98.6, Expect=1e-21]} {Smed: dd_Smed_v6_15102_0_7, dd_Smed_v6_15102_0_7, [Score=178, Expect=5e-50]} {RNA1509_58462} {RNA1310_11701} {RNA815_12354}
52. MligTC455_45179 4166 86.78 Mlig455_048432

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.401

CFAP20 1.795 - - - 0.844 0.951 - Mlig455_048432 {REF} {Length: 1648} {Pfam: Protein of unknown function (DUF667) [PF05018.15, score=310.7]} {Human: ENSG00000070761, CFAP20, cilia and flagella associated protein 20, [RH, Score=367, Expect=4e-131]} {Mouse: ENSMUSG00000031796, Cfap20, cilia and flagella associated protein 20, [RH, Score=370, Expect=2e-132]} {Dmel: FBgn0032248, Bug22, Basal body up regulated gene 22, [RH, Score=368, Expect=9e-132]} {Celegans: WBGene00008288, C54C6.6, Cilia- and flagella-associated protein 20, [RH, Score=345, Expect=1e-122]} {Smed: dd_Smed_v6_4843_0_1, dd_Smed_v6_4843_0_1, [RH, Score=362, Expect=2e-129]} {RNA1509_1898} {RNA1310_20376.1} {RNA815_8129.1}
53. MligTC455_26414 375 7.8 Mlig455_001503

Neo: -

Age: -

1.786 - - - - 0.965 0.821 Mlig455_001503 {REF} {Length: 3655} {TRANSSPLICED} {Pfam: Family of unknown function (DUF5580) [PF17743.3, score=85.6]} {Smed: dd_Smed_v6_9326_0_1, dd_Smed_v6_9326_0_1, [Score=167, Expect=1e-44]} {RNA1509_4141} {RNA1310_6622.2} {RNA815_8857}
54. MligTC455_47244 216 4.49 Mlig455_016130

Neo: -

Age: -

Region-enriched R2: 3.391/0.02151
Region-enriched R6: 2.922/0.03099

1.771 - - 0.962 - 0.809 - Mlig455_016130 {REF} {Length: 3312} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=27.9]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=20.5]} {Smed: dd_Smed_v6_24733_0_1, dd_Smed_v6_24733_0_1, [RH, Score=231, Expect=1e-71]} {RNA1509_41111} {RNA1310_18481.1} {RNA815_10445}
55. MligTC455_51903 1283 26.73 Mlig455_021657, Mlig455_067458

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.872

CHRNB1, CHRNB3 1.77 - - 0.802 - 0.968 -

Mlig455_021657 {REF} {Length: 2044} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=147.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=73.5]} {Human: ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=193, Expect=5e-56]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=189, Expect=1e-54]} {Mouse: ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=187, Expect=8e-54]; ENSMUSG00000035594, Chrna5, cholinergic receptor, nicotinic, alpha polypeptide 5, [Score=186, Expect=1e-53]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=179, Expect=5e-51]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [Score=176, Expect=3e-49]} {Celegans: WBGene00006774, unc-38, Acetylcholine receptor subunit alpha-type unc-38, [Score=174, Expect=9e-49]} {Smed: dd_Smed_v6_2019_0_1, dd_Smed_v6_2019_0_1, [Score=346, Expect=9e-116]} {RNA1509_8724} {RNA1310_17144.1, RNA1509_8724} {RNA1509_8724, RNA815_6285}

Mlig455_067458 {REF} {Length: 1512} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=43.5]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=18.7]} {Human: ENSG00000283946, CHRNB1, cholinergic receptor nicotinic beta 1 subunit, [Score=48.1, Expect=7e-06]; ENSG00000170175, CHRNB1, cholinergic receptor nicotinic beta 1 subunit, [Score=48.1, Expect=7e-06]; ENSG00000117971, CHRNB4, cholinergic receptor nicotinic beta 4 subunit, [Score=47.8, Expect=1e-05]} {Mouse: ENSMUSG00000029205, Chrna9, cholinergic receptor, nicotinic, alpha polypeptide 9, [Score=47.4, Expect=1e-05]} {Celegans: WBGene00000055, acr-16, Acetylcholine receptor subunit alpha-type acr-16, [Score=46.6, Expect=1e-05]} {Smed: dd_Smed_v6_2019_0_1, dd_Smed_v6_2019_0_1, [Score=96.7, Expect=1e-22]} {RNA1509_8724} {RNA1310_17144.1} {RNA815_6285}
56. MligTC455_44971 99 2.07 Mlig455_055696

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.674

Region-enriched R4: 4.753/0.00442

ATP1B1 1.768 - - - 0.808 0.960 - Mlig455_055696 {REF} {Length: 2498} {TRANSSPLICED} {Pfam: Sodium / potassium ATPase beta chain [PF00287.20, score=206.1]} {Human: ENSG00000143153, ATP1B1, ATPase Na+/K+ transporting subunit beta 1, [RH, Score=125, Expect=7e-33]} {Mouse: ENSMUSG00000026576, Atp1b1, ATPase, Na+/K+ transporting, beta 1 polypeptide, [RH, Score=127, Expect=8e-34]} {Dmel: FBgn0032946, nrv3, nervana 3, [RH, Score=164, Expect=8e-48]} {Celegans: WBGene00007646, nkb-1, Sodium/potassium-transporting ATPase subunit beta-1, [Score=151, Expect=4e-43]} {Smed: dd_Smed_v6_7917_0_1, dd_Smed_v6_7917_0_1, [RH, Score=244, Expect=2e-79]} {RNA1509_10526} {RNA1310_27937} {RNA815_16874}
57. MligTC455_38205 600 12.5 Mlig455_057698

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.274

1.767 - 0.802 - - 0.965 - Mlig455_057698 {REF} {Length: 1671} {Pfam: Protein of unknown function with motif GDWWSH [PF15667.7, score=76.0]} {Smed: dd_Smed_v6_6622_0_1, dd_Smed_v6_6622_0_1, [RH, Score=116, Expect=1e-30]} {RNA1509_16386} {RNA1310_17948.1} {RNA815_6839.1}
58. MligTC455_33802 659 13.73 Mlig455_033383

Neo: -

Age: logFC(26M/2M)=-0.359

1.766 - - - 0.807 0.959 - Mlig455_033383 {REF} {Length: 3524} {RNA1509_14410, RNA1509_56133} {RNA1310_8398, RNA1509_56133} {RNA1509_56133, RNA815_14639}
59. MligTC455_41595 483 10.07 Mlig455_065096

Neo: -

Age: -

1.765 - - 0.813 - 0.952 - Mlig455_065096 {REF} {Length: 1103} {RNA1310_35732} {RNA815_16408}
60. MligTC455_52239 629 13.1 Mlig455_029233

Neo: -

Age: logFC(26M/2M)=-0.429

ABCG2 1.764 - - - - 0.955 0.809 Mlig455_029233 {REF} {Length: 3918} {Pfam: ABC-2 type transporter [PF01061.26, score=125.2]; ABC transporter [PF00005.29, score=73.3]; ABC-2 type transporter [PF19055.2, score=43.6]; AAA domain, putative AbiEii toxin, Type IV TA system [PF13304.8, score=31.5]; RecF/RecN/SMC N terminal domain [PF02463.21, score=23.9]; AAA domain [PF13476.8, score=20.9]} {Human: ENSG00000118777, ABCG2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=541, Expect=0.0]} {Mouse: ENSMUSG00000029802, Abcg2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=546, Expect=0.0]} {Dmel: FBgn0003996, w, white, [Score=257, Expect=4e-74]} {Celegans: WBGene00012925, wht-8, WHiTe (Drosophila) related ABC transporter, [RH, Score=259, Expect=1e-75]} {Smed: dd_Smed_v6_4225_0_2, dd_Smed_v6_4225_0_2, [RH, Score=689, Expect=0.0]} {RNA1509_2851} {RNA1310_949.2} {RNA815_1895}
61. MligTC455_38922 1324 27.57 Mlig455_055899

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.333

MX2 1.76 - - 0.806 - 0.954 - Mlig455_055899 {REF} {Length: 3320} {Pfam: Dynamin central region [PF01031.22, score=177.8]; Dynamin family [PF00350.25, score=125.7]; Dynamin GTPase effector domain [PF02212.20, score=46.3]; 50S ribosome-binding GTPase [PF01926.25, score=21.2]; AAA ATPase domain [PF13191.8, score=19.7]} {Human: ENSG00000183486, MX2, MX dynamin like GTPase 2, [Score=319, Expect=1e-97]} {Mouse: ENSMUSG00000023341, Mx2, MX dynamin-like GTPase 2, [Score=308, Expect=3e-94]} {Dmel: FBgn0003392, shi, shibire, [Score=182, Expect=9e-48]} {Celegans: WBGene00001130, dyn-1, Dynamin, [Score=176, Expect=6e-46]} {Smed: dd_Smed_v6_2583_0_1, dd_Smed_v6_2583_0_1, [Score=198, Expect=2e-53]} {RNA1509_37170, RNA1509_6400} {RNA1310_6542.1, RNA1509_37170, RNA1509_6400} {RNA1509_37170, RNA1509_6400, RNA815_1426.1}
62. MligTC455_36721 2549 53.11 Mlig455_053966, Mlig455_054039

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.124

Region-enriched R2: 3.194/0.00046
Region-enriched R6: 2.927/0.00039

1.751 - - 0.775 - 0.976 -

Mlig455_053966 {REF} {Length: 649} {Smed: dd_Smed_v6_4417_0_1, dd_Smed_v6_4417_0_1, [RH, Score=43.5, Expect=2e-06]} {RNA1509_53329} {RNA1310_42223} {RNA815_28749}

Mlig455_054039 {REF} {Length: 1204} {Smed: dd_Smed_v6_4417_0_1, dd_Smed_v6_4417_0_1, [RH, Score=43.5, Expect=2e-06]} {RNA1509_18828, RNA1509_53329} {RNA1310_42223, RNA1509_53329} {RNA1509_53329, RNA815_28749}
63. MligTC455_51902 1049 21.85 Mlig455_021705

Neo: -

Age: logFC(26M/2M)=-0.488

CHRNB3 1.738 - - 0.764 - 0.974 - Mlig455_021705 {REF} {Length: 1861} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=147.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=72.7]} {Human: ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=191, Expect=2e-55]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=189, Expect=2e-54]; ENSG00000169684, CHRNA5, cholinergic receptor nicotinic alpha 5 subunit, [Score=182, Expect=6e-52]} {Mouse: ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=186, Expect=2e-53]; ENSMUSG00000035594, Chrna5, cholinergic receptor, nicotinic, alpha polypeptide 5, [Score=185, Expect=2e-53]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=182, Expect=4e-52]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [Score=177, Expect=2e-49]} {Celegans: WBGene00006774, unc-38, Acetylcholine receptor subunit alpha-type unc-38, [Score=174, Expect=7e-49]} {Smed: dd_Smed_v6_2019_0_1, dd_Smed_v6_2019_0_1, [Score=347, Expect=6e-116]} {RNA1509_8724} {RNA1310_17144.1} {RNA815_6285}
64. MligTC455_46653 678 14.12 Mlig455_039570

Neo: -

Age: logFC(26M/2M)=0.275

EPS8L2 1.734 - - 0.957 0.777 - - Mlig455_039570 {REF} {Length: 3659} {TRANSSPLICED} {Pfam: Phosphotyrosine-binding domain [PF08416.15, score=42.2]; SH3 domain [PF00018.30, score=24.0]} {Human: ENSG00000177106, EPS8L2, EPS8 like 2, [RH, Score=158, Expect=5e-40]; ENSG00000151491, EPS8, epidermal growth factor receptor pathway substrate 8, [RH, Score=152, Expect=7e-38]} {Mouse: ENSMUSG00000015766, Eps8, epidermal growth factor receptor pathway substrate 8, [RH, Score=158, Expect=8e-40]; ENSMUSG00000025504, Eps8l2, EPS8-like 2, [RH, Score=154, Expect=1e-38]} {Dmel: FBgn0029095, aru, arouser, [Score=161, Expect=5e-41]} {Celegans: WBGene00001330, eps-8, EPS (Human endocytosis) related; Epidermal growth factor receptor pathway substrate 8 splice variant A, [RH, Score=213, Expect=6e-59]} {Smed: dd_Smed_v6_4256_0_1, dd_Smed_v6_4256_0_1, [RH, Score=79.3, Expect=3e-15]} {RNA1509_4398} {RNA1310_3514} {RNA815_6294}
65. MligTC455_43786 401 8.35 Mlig455_054385

Neo: -

Age: -

CCDC60 1.732 - - - 0.769 0.963 - Mlig455_054385 {REF} {Length: 3003} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4698) [PF15769.7, score=170.6]} {Human: ENSG00000183273, CCDC60, coiled-coil domain containing 60, [Score=62.8, Expect=2e-09]} {Mouse: ENSMUSG00000043913, Ccdc60, coiled-coil domain containing 60, [Score=62.4, Expect=1e-09]} {Smed: dd_Smed_v6_14286_0_1, dd_Smed_v6_14286_0_1, [Score=115, Expect=1e-26]} {RNA1509_58886} {RNA1310_1558.2} {RNA815_11153}
66. MligTC455_54188 1224 25.51 Mlig455_011257, Mlig455_011337, Mlig455_011343

Neo: -

Age: logFC(26M/2M)=-0.405

Region-enriched R2: 1.704/0.00045

TRPM3 1.725 - - 0.955 - 0.770 -

Mlig455_011257 {REF} {Length: 4016} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=57.4]; Ankyrin repeats (many copies) [PF13637.8, score=35.7]; Ankyrin repeat [PF13606.8, score=29.0]; Ankyrin repeats (many copies) [PF13857.8, score=19.6]} {RNA1509_6328} {RNA1310_1706} {RNA815_498}

Mlig455_011337 {REF} {Length: 4535} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=67.0]; Ankyrin repeats (many copies) [PF13637.8, score=42.0]; Ankyrin repeats (many copies) [PF13857.8, score=34.0]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=85.5, Expect=5e-16]; ENSG00000134160, TRPM1, transient receptor potential cation channel subfamily M member 1, [Score=83.6, Expect=2e-15]; ENSG00000274965, TRPM1, transient receptor potential cation channel subfamily M member 1, [Score=83.6, Expect=2e-15]; ENSG00000092439, TRPM7, transient receptor potential cation channel subfamily M member 7, [Score=81.3, Expect=1e-14]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=87.0, Expect=1e-16]; ENSMUSG00000030523, Trpm1, transient receptor potential cation channel, subfamily M, member 1, [Score=86.3, Expect=2e-16]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=77.0, Expect=1e-13]} {Celegans: WBGene00001651, gon-2, Transient receptor potential channel, [Score=68.9, Expect=2e-11]} {Smed: dd_Smed_v6_26251_0_1, dd_Smed_v6_26251_0_1, [Score=102, Expect=6e-22]} {RNA1509_6328} {RNA1310_1706, RNA1509_6328} {RNA1509_6328, RNA815_498}

Mlig455_011343 {REF} {Length: 5711} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=61.4]; Ankyrin repeats (many copies) [PF13637.8, score=46.8]; Ankyrin repeat [PF00023.32, score=23.9]; Ankyrin repeat [PF13606.8, score=20.5]; Ankyrin repeats (many copies) [PF13857.8, score=20.1]} {RNA1509_6328} {RNA1310_1706} {RNA815_498}
67. MligTC455_38636 879 18.3 Mlig455_015502

Neo: -

Age: Down-Up-Down

GLS 1.724 0.952 - - - 0.772 - Mlig455_015502 {REF} {Length: 2629} {Pfam: Glutaminase [PF04960.17, score=370.4]; EF-hand domain [PF17959.3, score=64.1]; Ankyrin repeats (many copies) [PF13637.8, score=41.7]; Ankyrin repeats (3 copies) [PF12796.9, score=39.9]; Ankyrin repeats (many copies) [PF13857.8, score=28.6]; Ankyrin repeat [PF13606.8, score=27.6]; Ankyrin repeat [PF00023.32, score=21.8]} {Human: ENSG00000115419, GLS, glutaminase, [RH, Score=577, Expect=0.0]; ENSG00000135423, GLS2, glutaminase 2, [RH, Score=576, Expect=0.0]} {Mouse: ENSMUSG00000026103, Gls, glutaminase, [RH, Score=579, Expect=0.0]; ENSMUSG00000044005, Gls2, glutaminase 2 (liver, mitochondrial), [RH, Score=576, Expect=0.0]} {Dmel: FBgn0261625, GLS, Glutaminase, [Score=570, Expect=0.0]} {Celegans: WBGene00008435, glna-2, Putative glutaminase 2, [Score=518, Expect=4e-178]} {Smed: dd_Smed_v6_15097_0_1, dd_Smed_v6_15097_0_1, [Score=452, Expect=2e-154]} {RNA1509_17301, RNA1509_32879, RNA1509_50826, RNA1509_5226} {RNA1310_9764.1, RNA1509_17301, RNA1509_32879, RNA1509_50826} {RNA1509_17301, RNA1509_32879, RNA1509_50826, RNA815_4546}
68. MligTC455_21803 1070 22.29 Mlig455_051085

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.341

1.721 - - 0.759 - 0.962 - Mlig455_051085 {REF} {Length: 13899} {TRANSSPLICED} {Smed: dd_Smed_v6_4420_0_2, dd_Smed_v6_4420_0_2, [Score=53.1, Expect=3e-06]} {RNA1509_25269} {RNA1310_284.1} {RNA815_96}
69. MligTC455_38369 100 2.08 Mlig455_026465

Neo: -

Age: -

SSUH2 1.719 - - - 0.767 0.952 - Mlig455_026465 {REF} {Length: 1913} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [RH, Score=238, Expect=2e-74]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [RH, Score=200, Expect=2e-60]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=122, Expect=4e-31]} {RNA1509_6425} {RNA1310_32434} {RNA815_16161}
70. MligTC455_20126 1086 22.63 Mlig455_049824

Neo: -

Age: -

SLC2A1 1.715 - - - 0.759 0.956 - Mlig455_049824 {REF} {Length: 3566} {Pfam: Sugar (and other) transporter [PF00083.26, score=307.8]; Major Facilitator Superfamily [PF07690.18, score=50.0]} {Human: ENSG00000117394, SLC2A1, solute carrier family 2 member 1, [Score=289, Expect=2e-92]; ENSG00000163581, SLC2A2, solute carrier family 2 member 2, [Score=275, Expect=1e-86]} {Mouse: ENSMUSG00000028645, Slc2a1, solute carrier family 2 (facilitated glucose transporter), member 1, [Score=287, Expect=6e-92]; ENSMUSG00000027690, Slc2a2, solute carrier family 2 (facilitated glucose transporter), member 2, [Score=278, Expect=5e-88]} {Dmel: FBgn0264574, Glut1, Glucose transporter 1, [Score=296, Expect=7e-95]} {Celegans: WBGene00019207, fgt-1, Facilitated glucose transporter protein 1, [Score=239, Expect=1e-73]} {Smed: dd_Smed_v6_4396_0_1, dd_Smed_v6_4396_0_1, [Score=247, Expect=6e-77]} {RNA1509_29953} {RNA1310_18869} {RNA815_4904.1}
71. MligTC455_35169 597 12.45 Mlig455_006683

Neo: -

Age: -

SYNCRIP 1.715 - - - 0.759 0.956 - Mlig455_006683 {REF} {Length: 3588} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=145.9]; RNA recognition motif [PF16367.7, score=35.5]; Heterogeneous nuclear ribonucleoprotein Q acidic domain [PF18360.3, score=27.9]} {Human: ENSG00000135316, SYNCRIP, synaptotagmin binding cytoplasmic RNA interacting protein, [Score=323, Expect=2e-100]; ENSG00000282958, HNRNPR, heterogeneous nuclear ribonucleoprotein R, [Score=313, Expect=1e-96]; ENSG00000125944, HNRNPR, heterogeneous nuclear ribonucleoprotein R, [Score=313, Expect=1e-96]} {Mouse: ENSMUSG00000032423, Syncrip, synaptotagmin binding, cytoplasmic RNA interacting protein, [Score=322, Expect=3e-100]; ENSMUSG00000066037, Hnrnpr, heterogeneous nuclear ribonucleoprotein R, [Score=313, Expect=1e-96]} {Dmel: FBgn0038826, Syp, Syncrip, [Score=338, Expect=1e-107]} {Celegans: WBGene00002000, hrp-2, HnRNP A1 homolog, [Score=270, Expect=3e-81]} {Smed: dd_Smed_v6_2228_0_1, dd_Smed_v6_2228_0_1, [Score=231, Expect=2e-66]} {RNA1509_14954, RNA1509_17079, RNA1509_30936, RNA1509_37637} {RNA1310_1635.1, RNA1509_14954, RNA1509_30936, RNA1509_37637} {RNA1509_14954, RNA1509_30936, RNA1509_37637, RNA815_959}
72. MligTC455_24516 292 6.08 Mlig455_035506

Neo: -

Age: -

PRKAR1B 1.713 - 0.757 - - 0.956 - Mlig455_035506 {REF} {Length: 3296} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=72.4]} {Human: ENSG00000188191, PRKAR1B, protein kinase cAMP-dependent type I regulatory subunit beta, [Score=53.9, Expect=7e-07]} {Mouse: ENSMUSG00000025855, Prkar1b, protein kinase, cAMP dependent regulatory, type I beta, [Score=53.5, Expect=7e-07]} {Dmel: FBgn0259243, Pka-R1, Protein kinase, cAMP-dependent, regulatory subunit type 1, [Score=50.4, Expect=5e-06]} {Celegans: WBGene00002190, kin-2, cAMP-dependent protein kinase regulatory subunit, [Score=48.9, Expect=1e-05]} {Smed: dd_Smed_v6_13623_0_1, dd_Smed_v6_13623_0_1, [Score=373, Expect=3e-118]} {RNA1509_48722} {RNA1310_4914, RNA1509_48722} {RNA1509_48722, RNA815_2637}
73. MligTC455_35639 3666 76.37 Mlig455_053362

Neo: -

Age: Down-Up-Up

UBE2A 1.712 - - - - 0.954 0.758 Mlig455_053362 {REF} {Length: 1192} {TRANSSPLICED} {Pfam: Ubiquitin-conjugating enzyme [PF00179.28, score=178.1]} {Human: ENSG00000077721, UBE2A, ubiquitin conjugating enzyme E2 A, [RH, Score=270, Expect=6e-94]; ENSG00000119048, UBE2B, ubiquitin conjugating enzyme E2 B, [RH, Score=268, Expect=2e-93]} {Mouse: ENSMUSG00000016308, Ube2a, ubiquitin-conjugating enzyme E2A, [RH, Score=270, Expect=4e-94]; ENSMUSG00000020390, Ube2b, ubiquitin-conjugating enzyme E2B, [RH, Score=268, Expect=2e-93]} {Dmel: FBgn0004436, Ubc6, Ubiquitin conjugating enzyme 6, [RH, Score=258, Expect=2e-89]} {Celegans: WBGene00006701, ubc-1, Ubiquitin-conjugating enzyme E2 1, [RH, Score=268, Expect=4e-93]} {Smed: dd_Smed_v6_3543_0_1, dd_Smed_v6_3543_0_1, [RH, Score=244, Expect=2e-84]} {RNA1509_17248, RNA1509_28415, RNA1509_56837, RNA1509_6326} {RNA1310_29040.1, RNA1509_17248, RNA1509_28415, RNA1509_56837, RNA1509_6326} {RNA1509_17248, RNA1509_28415, RNA1509_56837, RNA1509_6326, RNA815_13231}
74. MligTC455_30865 559 11.65 Mlig455_050410

Neo: -

Age: logFC(26M/2M)=-0.223

1.702 0.730 - - - 0.972 - Mlig455_050410 {REF} {Length: 2602} {TRANSSPLICED} {RNA1509_18063} {RNA1310_7936.1, RNA1509_18063} {RNA1509_18063, RNA815_2370.1}
75. MligTC455_50986 150 3.12 Mlig455_070765

Neo: -

Age: -

1.696 - - 0.951 0.745 - - Mlig455_070765 {REF} {Length: 381} {NoTransDecoderORF} {RNA1509_41927} {RNA1310_50890} {RNA815_282.1}
76. MligTC455_38921 1688 35.17 Mlig455_023977

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.453

MX2 1.689 0.731 - - - 0.958 - Mlig455_023977 {REF} {Length: 3870} {Pfam: Dynamin central region [PF01031.22, score=175.3]; Dynamin family [PF00350.25, score=125.4]; Dynamin GTPase effector domain [PF02212.20, score=47.1]; 50S ribosome-binding GTPase [PF01926.25, score=22.3]; AAA ATPase domain [PF13191.8, score=19.2]} {Human: ENSG00000183486, MX2, MX dynamin like GTPase 2, [Score=319, Expect=2e-97]} {Mouse: ENSMUSG00000023341, Mx2, MX dynamin-like GTPase 2, [Score=307, Expect=8e-94]} {Dmel: FBgn0003392, shi, shibire, [Score=181, Expect=2e-47]} {Celegans: WBGene00001130, dyn-1, Dynamin, [Score=177, Expect=3e-46]} {Smed: dd_Smed_v6_2583_0_1, dd_Smed_v6_2583_0_1, [Score=194, Expect=3e-52]} {RNA1509_17985, RNA1509_34505, RNA1509_40252} {RNA1310_6542.1, RNA1509_17985, RNA1509_34505, RNA1509_40252} {RNA1509_17985, RNA1509_34505, RNA1509_40252, RNA815_1426.1}
77. MligTC455_27882 254 5.29 Mlig455_037128

Neo: -

Age: -

PRKAA2 1.684 - - 0.728 - 0.956 - Mlig455_037128 {REF} {Length: 3066} {Pfam: Protein kinase domain [PF00069.27, score=262.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=153.1]; Adenylate sensor of SNF1-like protein kinase [PF16579.7, score=44.1]; Kinase-like [PF14531.8, score=23.9]; Phosphotransferase enzyme family [PF01636.25, score=18.9]} {Human: ENSG00000162409, PRKAA2, protein kinase AMP-activated catalytic subunit alpha 2, [Score=500, Expect=1e-171]} {Mouse: ENSMUSG00000028518, Prkaa2, protein kinase, AMP-activated, alpha 2 catalytic subunit, [Score=493, Expect=6e-169]; ENSMUSG00000050697, Prkaa1, protein kinase, AMP-activated, alpha 1 catalytic subunit, [Score=473, Expect=8e-161]} {Dmel: FBgn0023169, AMPKalpha, AMP-activated protein kinase alpha subunit, [Score=537, Expect=0.0]} {Celegans: WBGene00020142, aak-2, 5'-AMP-activated protein kinase catalytic subunit alpha-2, [Score=503, Expect=4e-173]} {Smed: dd_Smed_v6_2538_0_1, dd_Smed_v6_2538_0_1, [Score=545, Expect=0.0]} {RNA1509_15569} {RNA1310_12572} {RNA815_3809}
78. MligTC455_33979 345 7.18 Mlig455_021634, Mlig455_021687

Neo: -

Age: Up-Down-Down

Region-enriched R6: 2.317/0.04233

FAT4 1.68 - - 0.959 - 0.721 -

Mlig455_021634 {REF} {Length: 15637} {Pfam: Cadherin domain [PF00028.19, score=1053.7]; Cadherin-like [PF08266.14, score=72.1]; Cadherin-like [PF16184.7, score=70.5]; EGF-like domain [PF00008.29, score=63.5]; Laminin G domain [PF02210.26, score=34.1]; Cadherin prodomain like [PF08758.13, score=32.3]; Human growth factor-like EGF [PF12661.9, score=29.7]; RET Cadherin like domain 1 [PF17756.3, score=23.0]; Calcium-binding EGF domain [PF07645.17, score=20.1]} {Human: ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=1268, Expect=0.0]} {Mouse: ENSMUSG00000046743, Fat4, FAT atypical cadherin 4, [RH, Score=1254, Expect=0.0]} {Dmel: FBgn0001075, ft, fat, [Score=1296, Expect=0.0]} {Celegans: WBGene00019994, cdh-1, CaDHerin family, [Score=261, Expect=4e-69]} {Smed: dd_Smed_v6_12707_0_1, dd_Smed_v6_12707_0_1, [RH, Score=739, Expect=0.0]} {RNA1509_5577, RNA1509_58023} {RNA1310_180, RNA1509_58023} {RNA1509_58023, RNA815_3956}

Mlig455_021687 {REF} {Length: 14771} {Pfam: Cadherin domain [PF00028.19, score=850.5]; EGF-like domain [PF00008.29, score=64.7]; Cadherin-like [PF08266.14, score=63.5]; Cadherin-like [PF16184.7, score=48.8]; Laminin G domain [PF02210.26, score=33.7]; Human growth factor-like EGF [PF12661.9, score=28.7]; Calcium-binding EGF domain [PF07645.17, score=20.4]} {Human: ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=879, Expect=0.0]} {Mouse: ENSMUSG00000046743, Fat4, FAT atypical cadherin 4, [Score=868, Expect=0.0]} {Dmel: FBgn0001075, ft, fat, [Score=949, Expect=0.0]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=238, Expect=5e-62]} {Smed: dd_Smed_v6_12707_0_1, dd_Smed_v6_12707_0_1, [RH, Score=446, Expect=3e-125]} {RNA1509_5577} {RNA1310_12081} {RNA815_14856}
79. MligTC455_39145 860 17.92 Mlig455_045710

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.035/0.04635

1.679 - 0.719 - - 0.960 - Mlig455_045710 {REF} {Length: 2657} {Pfam: Family of unknown function (DUF5580) [PF17743.3, score=80.4]} {Smed: dd_Smed_v6_9326_0_1, dd_Smed_v6_9326_0_1, [RH, Score=180, Expect=1e-49]} {RNA1509_11160, RNA1509_32698} {RNA1310_8387, RNA1509_11160, RNA1509_32698} {RNA1509_11160, RNA1509_32698, RNA815_15696.1}
80. MligTC455_45085 848 17.67 Mlig455_019350, Mlig455_019569, Mlig455_059128

Neo: -

Age: -

Region-enriched R2: 3.751/0.00011
Region-enriched R7: 2.382/0.02974

1.676 - - 0.709 - 0.967 -

Mlig455_019350 {REF} {Length: 2183} {Pfam: Thrombospondin type 1 domain [PF19030.2, score=27.8]} {RNA1509_40461} {RNA1310_18714.1, RNA1509_40461} {RNA1509_40461, RNA815_7309}

Mlig455_019569 {REF} {Length: 2135} {Pfam: Thrombospondin type 1 domain [PF19030.2, score=27.9]} {RNA1509_40461} {RNA1310_18714.1} {RNA815_7309}

Mlig455_059128 {REF} {Length: 2080} {Pfam: Thrombospondin type 1 domain [PF19030.2, score=27.9]} {RNA1509_40461} {RNA1310_18714.1} {RNA815_7309}
81. MligTC455_31803 504 10.5 Mlig455_059772

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.440

EFCAB6 1.669 - - - - 0.964 0.705 Mlig455_059772 {REF} {Length: 3998} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=86.2]; EF-hand domain [PF08976.13, score=70.4]; EF-hand domain pair [PF13833.8, score=62.2]; EF-hand domain [PF13405.8, score=57.9]; EF hand [PF00036.34, score=53.9]; EF-hand domain [PF14658.8, score=35.9]; Family of unknown function (DUF5580) [PF17743.3, score=28.0]; EF hand [PF13202.8, score=22.4]} {Human: ENSG00000186976, EFCAB6, EF-hand calcium binding domain 6, [Score=89.7, Expect=2e-17]} {Mouse: ENSMUSG00000022441, Efcab6, EF-hand calcium binding domain 6, [Score=76.3, Expect=2e-13]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=49.3, Expect=2e-06]} {Celegans: WBGene00017394, cal-8, CALmodulin related genes, [Score=50.8, Expect=3e-07]} {Smed: dd_Smed_v6_20435_0_1, dd_Smed_v6_20435_0_1, [Score=154, Expect=9e-40]} {RNA1509_7148} {RNA1310_3069.1, RNA1509_7148} {RNA1509_7148, RNA815_3758}
82. MligTC455_19266 1038 21.61 Mlig455_004528, Mlig455_028530

Neo: -

Age: -

Region-specific R2: 2.706

Region-enriched R2: 1.766/0.00005

NCALD 1.665 - - 0.706 - 0.959 -

Mlig455_004528 {REF} {Length: 3958} {tRNA: Val(CAC),pseudo, score=38.6} {Pfam: EF-hand domain pair [PF13499.8, score=74.4]; EF hand [PF00036.34, score=71.3]; EF-hand domain [PF13405.8, score=66.3]; EF hand [PF13202.8, score=62.7]; EF-hand domain pair [PF13833.8, score=50.8]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=22.1]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=19.3]} {Human: ENSG00000104490, NCALD, neurocalcin delta, [Score=194, Expect=4e-63]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=191, Expect=1e-61]; ENSG00000121905, HPCA, hippocalcin, [Score=185, Expect=1e-59]} {Mouse: ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=194, Expect=2e-63]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=191, Expect=8e-62]; ENSMUSG00000028785, Hpca, hippocalcin, [Score=185, Expect=1e-59]} {Dmel: FBgn0036926, CG7646, [RH, Score=221, Expect=6e-74]} {Celegans: WBGene00003564, ncs-2, Neuronal calcium sensor 2, [Score=238, Expect=6e-81]} {Smed: dd_Smed_v6_5266_0_1, dd_Smed_v6_5266_0_1, [RH, Score=359, Expect=8e-129]} {RNA1509_14564} {RNA1310_18405, RNA1509_14564} {RNA1509_14564, RNA815_10180.1}

Mlig455_028530 {REF} {Length: 3453} {tRNA: Val(CAC),pseudo, score=38.6} {Pfam: EF-hand domain pair [PF13499.8, score=74.4]; EF hand [PF00036.34, score=71.3]; EF-hand domain [PF13405.8, score=66.3]; EF hand [PF13202.8, score=62.7]; EF-hand domain pair [PF13833.8, score=50.8]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=22.1]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=19.3]} {Human: ENSG00000104490, NCALD, neurocalcin delta, [Score=194, Expect=4e-63]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=191, Expect=1e-61]; ENSG00000121905, HPCA, hippocalcin, [Score=185, Expect=1e-59]} {Mouse: ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=194, Expect=2e-63]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=191, Expect=8e-62]; ENSMUSG00000028785, Hpca, hippocalcin, [Score=185, Expect=1e-59]} {Dmel: FBgn0036926, CG7646, [RH, Score=221, Expect=6e-74]} {Celegans: WBGene00003564, ncs-2, Neuronal calcium sensor 2, [Score=238, Expect=6e-81]} {Smed: dd_Smed_v6_5266_0_1, dd_Smed_v6_5266_0_1, [RH, Score=359, Expect=8e-129]} {RNA1509_13995, RNA1509_14564, RNA1509_30926} {RNA1310_18405, RNA1509_13995, RNA1509_30926} {RNA1509_13995, RNA1509_30926, RNA815_10180.1}
83. MligTC455_45833 435 9.07 Mlig455_024105

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.498

CHRNA3 1.658 - - 0.706 - 0.952 - Mlig455_024105 {REF} {Length: 2298} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=246.4]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=215.5]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=391, Expect=4e-131]; ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=378, Expect=7e-126]; ENSG00000117971, CHRNB4, cholinergic receptor nicotinic beta 4 subunit, [Score=372, Expect=1e-123]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=389, Expect=2e-130]} {Dmel: FBgn0000038, nAChRbeta1, nicotinic Acetylcholine Receptor beta1, [RH, Score=502, Expect=2e-174]} {Celegans: WBGene00006765, unc-29, Acetylcholine receptor subunit beta-type unc-29, [RH, Score=401, Expect=2e-135]} {Smed: dd_Smed_v6_12535_0_1, dd_Smed_v6_12535_0_1, [Score=465, Expect=4e-159]} {RNA1509_30259, RNA1509_56781} {RNA1310_14242, RNA1509_30259, RNA1509_56781} {RNA1509_30259, RNA1509_56781, RNA815_14328}
84. MligTC455_22773 138 2.87 Mlig455_026562

Neo: -

Age: -

1.652 - - 0.702 - 0.950 - Mlig455_026562 {REF} {Length: 1348} {NoTransDecoderORF} {RNA1310_69367} {RNA815_45046}
85. MligTC455_12056 104 2.16 Mlig455_062444

Neo: -

Age: Down-Up-Down

IGFALS 0.978 - - - - 0.978 - Mlig455_062444 {REF} {Length: 4624} {Pfam: Leucine rich repeat [PF13855.8, score=119.1]; Leucine Rich repeats (2 copies) [PF12799.9, score=66.1]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=56.3]; Leucine-rich repeat [PF14580.8, score=29.8]; Leucine Rich Repeat [PF00560.35, score=22.9]} {Human: ENSG00000099769, IGFALS, insulin like growth factor binding protein acid labile subunit, [Score=82.8, Expect=2e-15]; ENSG00000255690, TRIL, TLR4 interactor with leucine rich repeats, [Score=82.4, Expect=2e-15]; ENSG00000139263, LRIG3, leucine rich repeats and immunoglobulin like domains 3, [Score=80.9, Expect=8e-15]} {Mouse: ENSMUSG00000051379, Flrt3, fibronectin leucine rich transmembrane protein 3, [RH, Score=83.2, Expect=7e-16]} {Dmel: FBgn0259677, CG42346, [Score=78.2, Expect=4e-14]} {Celegans: WBGene00020649, sma-10, Leucine-rich repeats and immunoglobulin-like domains protein sma-10, [Score=77.8, Expect=2e-14]} {Smed: dd_Smed_v6_13247_0_1, dd_Smed_v6_13247_0_1, [RH, Score=105, Expect=7e-23]} {RNA1509_11667} {RNA1310_3242, RNA1509_11667} {RNA1509_11667, RNA815_522}
86. MligTC455_17646 1198 24.96 Mlig455_048620, Mlig455_048699, Mlig455_048734

Neo: -

Age: logFC(26M/2M)=0.248

Region-enriched R2: 1.637/0.02593
Region-enriched R5: 1.108/0.02454

WDR86 0.966 - - - - 0.966 -

Mlig455_048620 {REF} {Length: 3284} {Pfam: WD domain, G-beta repeat [PF00400.34, score=149.4]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=42.9]; PQQ-like domain [PF13570.8, score=25.8]; Nucleoporin Nup120/160 [PF11715.10, score=22.0]} {Human: ENSG00000187260, WDR86, WD repeat domain 86, [RH, Score=318, Expect=6e-105]} {Mouse: ENSMUSG00000055235, Wdr86, WD repeat domain 86, [RH, Score=313, Expect=2e-103]} {Dmel: FBgn0283468, slmb, supernumerary limbs, [Score=125, Expect=2e-30]} {Celegans: WBGene00004767, sel-10, F-box/WD repeat-containing protein sel-10, [Score=135, Expect=2e-34]} {Smed: dd_Smed_v6_19827_0_1, dd_Smed_v6_19827_0_1, [RH, Score=425, Expect=5e-147]} {RNA1509_20850} {RNA1310_16023.1, RNA1509_20850} {RNA1509_20850, RNA815_7261}

Mlig455_048699 {REF} {Length: 2794} {Pfam: WD domain, G-beta repeat [PF00400.34, score=149.1]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=42.7]; PQQ-like domain [PF13570.8, score=25.5]; Nucleoporin Nup120/160 [PF11715.10, score=22.0]} {Human: ENSG00000187260, WDR86, WD repeat domain 86, [RH, Score=318, Expect=6e-105]} {Mouse: ENSMUSG00000055235, Wdr86, WD repeat domain 86, [RH, Score=314, Expect=2e-103]} {Dmel: FBgn0283468, slmb, supernumerary limbs, [Score=124, Expect=2e-30]} {Celegans: WBGene00004767, sel-10, F-box/WD repeat-containing protein sel-10, [Score=136, Expect=2e-34]} {Smed: dd_Smed_v6_19827_0_1, dd_Smed_v6_19827_0_1, [RH, Score=423, Expect=4e-146]} {RNA1509_20850} {RNA1310_16023.2} {RNA815_7261}

Mlig455_048734 {REF} {Length: 3308} {Pfam: WD domain, G-beta repeat [PF00400.34, score=149.4]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=42.9]; PQQ-like domain [PF13570.8, score=25.8]; Nucleoporin Nup120/160 [PF11715.10, score=22.0]} {Human: ENSG00000187260, WDR86, WD repeat domain 86, [RH, Score=318, Expect=6e-105]} {Mouse: ENSMUSG00000055235, Wdr86, WD repeat domain 86, [RH, Score=313, Expect=2e-103]} {Dmel: FBgn0283468, slmb, supernumerary limbs, [Score=125, Expect=2e-30]} {Celegans: WBGene00004767, sel-10, F-box/WD repeat-containing protein sel-10, [Score=135, Expect=2e-34]} {Smed: dd_Smed_v6_19827_0_1, dd_Smed_v6_19827_0_1, [RH, Score=425, Expect=5e-147]} {RNA1509_20850} {RNA1310_16023.1} {RNA815_7261}
87. MligTC455_42821 155 3.22 Mlig455_040440

Neo: -

Age: -

LARGE1 0.965 - - - - 0.965 - Mlig455_040440 {REF} {Length: 5152} {TRANSSPLICED} {Pfam: Glycosyl-transferase for dystroglycan [PF13896.8, score=181.1]; Glycosyl transferase family 8 [PF01501.22, score=52.6]} {Human: ENSG00000133424, LARGE1, LARGE xylosyl- and glucuronyltransferase 1, [RH, Score=649, Expect=0.0]; ENSG00000165905, LARGE2, LARGE xylosyl- and glucuronyltransferase 2, [RH, Score=620, Expect=0.0]} {Mouse: ENSMUSG00000004383, Large1, LARGE xylosyl- and glucuronyltransferase 1, [RH, Score=646, Expect=0.0]; ENSMUSG00000040434, Large2, LARGE xylosyl- and glucuronyltransferase 2, [RH, Score=622, Expect=0.0]} {Dmel: FBgn0032457, CG15483, [RH, Score=67.8, Expect=1e-11]} {Celegans: WBGene00010716, lge-1, Glycosyltransferase-like protein LARGE, [RH, Score=304, Expect=1e-93]} {Smed: dd_Smed_v6_15269_0_1, dd_Smed_v6_15269_0_1, [RH, Score=484, Expect=6e-165]} {RNA1509_51185} {RNA1310_11436, RNA1509_51185} {RNA1509_51185, RNA815_10031}
88. MligTC455_17206 312 6.49 Mlig455_002084, Mlig455_002192

Neo: -

Age: -

0.964 - - - - 0.964 -

Mlig455_002084 {REF} {Length: 2675} {RNA1509_14972} {RNA1310_7695.1} {RNA815_2358.1}

Mlig455_002192 {REF} {Length: 2459} {RNA1509_36449} {RNA1310_7695.1} {RNA815_2358.1}
89. MligTC455_35968 520 10.84 Mlig455_016036, Mlig455_054955

Neo: -

Age: -

CAMK1 0.964 - - - - 0.964 -

Mlig455_016036 {REF} {Length: 2967} {Pfam: Protein kinase domain [PF00069.27, score=253.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=125.1]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=23.3]; Kinase-like [PF14531.8, score=21.6]; RIO1 family [PF01163.24, score=20.8]} {Human: ENSG00000134072, CAMK1, calcium/calmodulin dependent protein kinase I, [RH, Score=431, Expect=6e-151]; ENSG00000183049, CAMK1D, calcium/calmodulin dependent protein kinase ID, [RH, Score=419, Expect=8e-146]} {Mouse: ENSMUSG00000030272, Camk1, calcium/calmodulin-dependent protein kinase I, [RH, Score=434, Expect=4e-152]; ENSMUSG00000039145, Camk1d, calcium/calmodulin-dependent protein kinase ID, [RH, Score=421, Expect=7e-147]} {Dmel: FBgn0016126, CaMKI, Calcium/calmodulin-dependent protein kinase I, [RH, Score=432, Expect=2e-151]} {Celegans: WBGene00000553, cmk-1, Calcium/calmodulin-dependent protein kinase type 1, [RH, Score=419, Expect=3e-147]} {Smed: dd_Smed_v6_5783_0_1, dd_Smed_v6_5783_0_1, [RH, Score=540, Expect=0.0]} {RNA1509_24682} {RNA1310_6913.1, RNA1509_24682} {RNA1509_24682, RNA815_5590.1}

Mlig455_054955 {REF} {Length: 3185} {Pfam: Protein kinase domain [PF00069.27, score=248.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=122.4]; ABC1 atypical kinase-like domain [PF03109.18, score=31.7]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=23.3]; Kinase-like [PF14531.8, score=21.5]; RIO1 family [PF01163.24, score=20.8]} {Human: ENSG00000134072, CAMK1, calcium/calmodulin dependent protein kinase I, [RH, Score=427, Expect=2e-149]; ENSG00000183049, CAMK1D, calcium/calmodulin dependent protein kinase ID, [RH, Score=415, Expect=8e-145]} {Mouse: ENSMUSG00000030272, Camk1, calcium/calmodulin-dependent protein kinase I, [RH, Score=429, Expect=2e-150]; ENSMUSG00000039145, Camk1d, calcium/calmodulin-dependent protein kinase ID, [RH, Score=418, Expect=1e-145]} {Dmel: FBgn0016126, CaMKI, Calcium/calmodulin-dependent protein kinase I, [RH, Score=431, Expect=4e-151]} {Celegans: WBGene00000553, cmk-1, Calcium/calmodulin-dependent protein kinase type 1, [RH, Score=414, Expect=3e-145]} {Smed: dd_Smed_v6_5783_0_1, dd_Smed_v6_5783_0_1, [RH, Score=539, Expect=0.0]} {RNA1509_24682} {RNA1310_6913.1} {RNA815_5590.1}
90. MligTC455_54177 858 17.88 Mlig455_020727

Neo: -

Age: Down-Down-Up

Region-enriched R8: 2.370/0.00010
Region-enriched R7: 2.006/0.00008

0.964 - - - - 0.964 - Mlig455_020727 {REF} {Length: 2702} {Smed: dd_Smed_v6_5057_0_1, dd_Smed_v6_5057_0_1, [RH, Score=91.7, Expect=4e-20]} {RNA1509_10580} {RNA1310_9366} {RNA815_2566}
91. MligTC455_17333 251 5.22 Mlig455_018094

Neo: -

Age: logFC(26M/2M)=-0.324

CFAP77 0.962 - - - - 0.962 - Mlig455_018094 {REF} {Length: 1669} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4483) [PF14825.8, score=38.0]} {Human: ENSG00000188523, CFAP77, cilia and flagella associated protein 77, [Score=62.4, Expect=1e-10]} {Smed: dd_Smed_v6_5179_0_1, dd_Smed_v6_5179_0_1, [Score=64.3, Expect=5e-12]} {RNA1509_11420} {RNA1310_11821} {RNA815_16183}
92. MligTC455_33217 350 7.3 Mlig455_017510, Mlig455_025979, Mlig455_030680, Mlig455_060677, Mlig455_070125

Neo: -

Age: Down-Up-Down

0.96 - - - - 0.960 -

Mlig455_017510 {REF} {Length: 518} {NoTransDecoderORF} {RNA1509_35799} {RNA1310_37183} {RNA815_7155}

Mlig455_025979 {REF} {Length: 1819} {NoTransDecoderORF} {RNA1509_44389} {RNA1310_14765.1} {RNA815_7155}

Mlig455_030680 {REF} {Length: 1230} {NoTransDecoderORF} {RNA1509_44389} {RNA1310_14765.2} {RNA815_7155}

Mlig455_060677 {REF} {Length: 6928} {NoTransDecoderORF} {RNA1509_33795, RNA1509_44389} {RNA1310_14765.2, RNA1509_33795} {RNA1509_33795, RNA815_7155}

Mlig455_070125 {REF} {Length: 5305} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_44389} {RNA1310_14765.2} {RNA815_7155}
93. MligTC455_42820 154 3.21 Mlig455_029557

Neo: -

Age: -

LARGE1 0.96 - - - - 0.960 - Mlig455_029557 {REF} {Length: 1795} {Pfam: Glycosyl-transferase for dystroglycan [PF13896.8, score=135.5]} {Human: ENSG00000133424, LARGE1, LARGE xylosyl- and glucuronyltransferase 1, [Score=262, Expect=4e-82]} {Mouse: ENSMUSG00000004383, Large1, LARGE xylosyl- and glucuronyltransferase 1, [Score=262, Expect=8e-82]; ENSMUSG00000040434, Large2, LARGE xylosyl- and glucuronyltransferase 2, [Score=258, Expect=4e-81]} {Dmel: FBgn0032457, CG15483, [Score=62.8, Expect=7e-11]} {Celegans: WBGene00010716, lge-1, Glycosyltransferase-like protein LARGE, [Score=127, Expect=5e-33]} {Smed: dd_Smed_v6_15269_0_1, dd_Smed_v6_15269_0_1, [Score=290, Expect=2e-95]} {RNA1509_47482} {RNA1310_56850.2} {RNA815_37190}
94. MligTC455_41489 218 4.55 Mlig455_063751

Neo: -

Age: -

SLC18A3 0.959 - - - - 0.959 - Mlig455_063751 {REF} {Length: 1991} {Pfam: Major Facilitator Superfamily [PF07690.18, score=95.8]; MFS_1 like family [PF12832.9, score=26.3]} {Human: ENSG00000187714, SLC18A3, solute carrier family 18 member A3, [Score=103, Expect=5e-23]; ENSG00000036565, SLC18A1, solute carrier family 18 member A1, [Score=99.4, Expect=1e-21]} {Mouse: ENSMUSG00000100241, Slc18a3, solute carrier family 18 (vesicular monoamine), member 3, [Score=107, Expect=3e-24]} {Dmel: FBgn0270928, VAChT, Vesicular acetylcholine transporter, [Score=199, Expect=1e-56]} {Celegans: WBGene00006756, unc-17, Vesicular acetylcholine transporter unc-17, [Score=182, Expect=3e-51]} {Smed: dd_Smed_v6_11630_0_1, dd_Smed_v6_11630_0_1, [Score=187, Expect=4e-53]} {RNA1509_37669} {RNA1310_14899.1, RNA1509_37669} {RNA1509_37669, RNA815_15265}
95. MligTC455_47436 119 2.48 Mlig455_049081

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=-0.598

SYT14 0.959 - - - - 0.959 - Mlig455_049081 {REF} {Length: 1963} {Pfam: C2 domain [PF00168.32, score=35.1]} {Human: ENSG00000143469, SYT14, synaptotagmin 14, [Score=173, Expect=7e-48]; ENSG00000139973, SYT16, synaptotagmin 16, [Score=169, Expect=2e-45]} {Mouse: ENSMUSG00000016200, Syt14, synaptotagmin XIV, [Score=169, Expect=2e-46]} {Dmel: FBgn0261086, Syt14, Synaptotagmin 14, [Score=135, Expect=2e-34]} {Smed: dd_Smed_v6_9164_0_3, dd_Smed_v6_9164_0_3, [Score=103, Expect=5e-24]} {RNA1509_43544} {RNA1310_28789} {RNA815_16692}
96. MligTC455_16750 45 0.93 Mlig455_056697

Neo: -

Age: -

0.957 - - - - 0.957 - Mlig455_056697 {REF} {Length: 1207} {RNA1509_39963} {RNA1310_3400} {RNA815_5315}
97. MligTC455_08125 14 0.29 Mlig455_040138

Neo: -

Age: -

0.955 - - - - 0.955 - Mlig455_040138 {REF} {Length: 1618} {Pfam: Homeodomain-like domain [PF13565.8, score=23.3]} {RNA1509_55432} {RNA1310_36253} {RNA815_6705.1}
98. MligTC455_45832 434 9.04 Mlig455_031218

Neo: -

Age: logFC(26M/2M)=-0.554

Regeneration-depleted BL: -8.141
Regeneration-depleted R5: -5.539
Regeneration-depleted R6: -4.514
Regeneration-depleted R4: -4.459
Regeneration-depleted R3: -3.400
Regeneration-depleted R2: -2.225

CYP2J2 0.955 - - 0.955 - - - Mlig455_031218 {REF} {Length: 2567} {Pfam: Cytochrome P450 [PF00067.24, score=269.5]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=231, Expect=5e-69]} {Mouse: ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=231, Expect=4e-69]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [Score=229, Expect=2e-68]; ENSMUSG00000027983, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=226, Expect=8e-67]; ENSMUSG00000116063, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=226, Expect=8e-67]} {Dmel: FBgn0036910, Cyp305a1, [Score=166, Expect=7e-45]} {Celegans: WBGene00012448, cyp-33D3, CYtochrome P450 family, [Score=208, Expect=9e-61]} {Smed: dd_Smed_v6_8600_0_1, dd_Smed_v6_8600_0_1, [Score=221, Expect=1e-65]} {RNA1509_10802} {RNA1310_15759, RNA1509_10802} {RNA1509_10802, RNA815_10494}
99. MligTC455_26999 330 6.88 Mlig455_037719, Mlig455_037789

Neo: -

Age: -

RBM12B 0.954 - - - - 0.954 -

Mlig455_037719 {REF} {Length: 3624} {Pfam: Mitochondrial distribution and morphology protein 10 [PF12519.10, score=19.6]} {Human: ENSG00000183808, RBM12B, RNA binding motif protein 12B, [Score=58.9, Expect=4e-08]} {RNA1509_40809} {RNA1310_8203} {RNA815_13132}

Mlig455_037789 {REF} {Length: 3262} {Human: ENSG00000183808, RBM12B, RNA binding motif protein 12B, [Score=61.2, Expect=7e-09]} {RNA1310_8203} {RNA815_13132}
100. MligTC455_31802 524 10.92 Mlig455_055004

Neo: -

Age: logFC(26M/2M)=-0.336

EFCAB6 0.954 - - - - 0.954 - Mlig455_055004 {REF} {Length: 4093} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=77.2]; EF-hand domain pair [PF13833.8, score=63.0]; EF-hand domain [PF08976.13, score=57.8]; EF-hand domain [PF13405.8, score=55.2]; EF hand [PF00036.34, score=52.6]; Family of unknown function (DUF5580) [PF17743.3, score=28.1]; EF-hand domain [PF14658.8, score=27.3]; EF hand [PF13202.8, score=22.4]} {Human: ENSG00000186976, EFCAB6, EF-hand calcium binding domain 6, [Score=79.7, Expect=2e-14]} {Mouse: ENSMUSG00000022441, Efcab6, EF-hand calcium binding domain 6, [Score=75.1, Expect=4e-13]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=49.3, Expect=2e-06]} {Celegans: WBGene00017394, cal-8, CALmodulin related genes, [Score=50.8, Expect=3e-07]} {Smed: dd_Smed_v6_20435_0_1, dd_Smed_v6_20435_0_1, [Score=154, Expect=2e-39]} {RNA1509_11692} {RNA1310_3239.1} {RNA815_3758}

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