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Results for MligTC455_49179

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_49179 1230 25.62 Mlig455_000575, Mlig455_030372

Neo: -

Age: Down-Up-Down

 GRIK1

Mlig455_000575 {REF} {Length: 3002} {Pfam: Ligand-gated ion channel [PF00060.28, score=56.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=22.4]; Receptor family ligand binding region [PF01094.30, score=21.2]} {Human: ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=76.6, Expect=1e-13]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=73.6, Expect=1e-12]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=73.9, Expect=6e-13]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=73.2, Expect=1e-12]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=66.2, Expect=9e-11]} {Smed: dd_Smed_v6_10048_0_1, dd_Smed_v6_10048_0_1, [Score=71.2, Expect=1e-12]} {RNA1509_5131} {RNA1310_3885, RNA1509_5131} {RNA1509_5131, RNA815_1090.1}

Mlig455_030372 {REF} {Length: 3002} {Pfam: Ligand-gated ion channel [PF00060.28, score=56.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=22.5]; Receptor family ligand binding region [PF01094.30, score=21.4]} {Human: ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=76.6, Expect=1e-13]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=73.6, Expect=1e-12]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=73.9, Expect=6e-13]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=73.2, Expect=1e-12]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=65.5, Expect=1e-10]} {Smed: dd_Smed_v6_10048_0_1, dd_Smed_v6_10048_0_1, [Score=71.6, Expect=1e-12]} {RNA1509_5131} {RNA1310_3885} {RNA815_1090.1}

Cumulative graph for MligTC455_49179

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.017 4.779 0.98826 1.00000
RegionR2 0.734 4.779 0.05483 0.28054
RegionR3 -0.061 4.779 0.86281 1.00000
RegionR4 -0.672 4.779 0.12110 0.34874
RegionR5 -0.718 4.779 0.04315 0.16840
RegionR6 -1.024 4.779 0.01079 0.17641
RegionR7 0.744 4.779 0.08233 0.55258
RegionR8 0.981 4.779 0.08439 0.55032

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.375 4.779 0.79171 1.00000
RegenerationR2 0.592 4.779 0.05076 0.37207
RegenerationR3 0.368 4.779 0.31737 0.74610
RegenerationR4 1.279 4.779 0.00087 0.03186
RegenerationR5 0.689 4.779 0.05989 0.38979
RegenerationR6 1.05 4.779 0.01108 0.12985
RegenerationBL 0.861 4.779 0.02481 0.17336
RegenerationTP 0.236 4.779 0.58601 0.95338


Genes with expression patterns similar to MligTC455_49179

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_49179 1230 25.62 Mlig455_000575, Mlig455_030372

Neo: -

Age: Down-Up-Down

 GRIK1 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_000575 {REF} {Length: 3002} {Pfam: Ligand-gated ion channel [PF00060.28, score=56.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=22.4]; Receptor family ligand binding region [PF01094.30, score=21.2]} {Human: ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=76.6, Expect=1e-13]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=73.6, Expect=1e-12]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=73.9, Expect=6e-13]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=73.2, Expect=1e-12]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=66.2, Expect=9e-11]} {Smed: dd_Smed_v6_10048_0_1, dd_Smed_v6_10048_0_1, [Score=71.2, Expect=1e-12]} {RNA1509_5131} {RNA1310_3885, RNA1509_5131} {RNA1509_5131, RNA815_1090.1}

Mlig455_030372 {REF} {Length: 3002} {Pfam: Ligand-gated ion channel [PF00060.28, score=56.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=22.5]; Receptor family ligand binding region [PF01094.30, score=21.4]} {Human: ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=76.6, Expect=1e-13]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=73.6, Expect=1e-12]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=73.9, Expect=6e-13]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=73.2, Expect=1e-12]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=65.5, Expect=1e-10]} {Smed: dd_Smed_v6_10048_0_1, dd_Smed_v6_10048_0_1, [Score=71.6, Expect=1e-12]} {RNA1509_5131} {RNA1310_3885} {RNA815_1090.1}
2. MligTC455_49180 501 10.44 Mlig455_030419

Neo: -

Age: logFC(26M/2M)=-0.221

 GRIK1 5.652 0.948 0.939 0.877 0.956 0.941 0.991 Mlig455_030419 {REF} {Length: 3001} {Pfam: Ligand-gated ion channel [PF00060.28, score=56.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=21.2]; Receptor family ligand binding region [PF01094.30, score=21.2]} {Human: ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=78.2, Expect=4e-14]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=75.5, Expect=3e-13]} {Mouse: ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=76.3, Expect=1e-13]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=75.5, Expect=2e-13]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=68.2, Expect=2e-11]} {Smed: dd_Smed_v6_10048_0_1, dd_Smed_v6_10048_0_1, [Score=73.2, Expect=4e-13]} {RNA1509_5131} {RNA1310_3885} {RNA815_1090.1}
3. MligTC455_43616 1798 37.45 Mlig455_024513

Neo: -

Age: logFC(26M/2M)=-0.338

Region-enriched R2: 1.066/0.02738

 CFAP57 3.46 - 0.793 0.844 0.864 0.959 - Mlig455_024513 {REF} {Length: 5805} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=65.8]; Crescentin protein [PF19220.2, score=26.3]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=25.5]; Autophagy protein 16 (ATG16) [PF08614.13, score=24.0]; Coiled-coil region of CCDC155 or KASH [PF14662.8, score=20.0]} {Human: ENSG00000243710, CFAP57, cilia and flagella associated protein 57, [RH, Score=1363, Expect=0.0]} {Mouse: ENSMUSG00000028730, Cfap57, cilia and flagella associated protein 57, [RH, Score=1360, Expect=0.0]} {Dmel: FBgn0034745, CG4329, [RH, Score=496, Expect=5e-155]} {Celegans: WBGene00003047, lis-1, Lissencephaly-1 homolog, [Score=55.1, Expect=2e-07]} {Smed: dd_Smed_v6_3323_0_1, dd_Smed_v6_3323_0_1, [RH, Score=1620, Expect=0.0]} {RNA1509_14259, RNA1509_18569, RNA1509_42897, RNA1509_836} {RNA1310_1737, RNA1509_14259, RNA1509_18569, RNA1509_42897} {RNA1509_14259, RNA1509_18569, RNA1509_42897, RNA815_558}
4. MligTC455_37308 1663 34.65 Mlig455_040453

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.651

 ARRDC1 3.378 - 0.765 - 0.749 0.950 0.914 Mlig455_040453 {REF} {Length: 2316} {Pfam: Arrestin (or S-antigen), N-terminal domain [PF00339.31, score=81.2]; Arrestin (or S-antigen), C-terminal domain [PF02752.24, score=63.8]} {Human: ENSG00000197070, ARRDC1, arrestin domain containing 1, [Score=80.5, Expect=1e-15]; ENSG00000140450, ARRDC4, arrestin domain containing 4, [Score=78.6, Expect=7e-15]} {Mouse: ENSMUSG00000026972, Arrdc1, arrestin domain containing 1, [Score=73.6, Expect=2e-13]} {Dmel: FBgn0035103, Vdup1, Vitamin D[[3]] up-regulated protein 1, [Score=90.9, Expect=1e-19]} {Celegans: WBGene00018060, arrd-18, ARRestin Domain protein, [Score=65.1, Expect=5e-11]} {RNA1509_2401, RNA1509_53571} {RNA1310_27725, RNA1509_53571} {RNA1509_53571, RNA815_11006.1}
5. MligTC455_53774 2623 54.65 Mlig455_039561, Mlig455_051366

Neo: -

Age: logFC(26M/2M)=-0.322

Region-enriched R4: 1.262/0.01773

 SPATA6 2.612 - 0.830 - - 0.968 0.814

Mlig455_039561 {REF} {Length: 2532} {TRANSSPLICED} {Pfam: Spermatogenesis-assoc protein 6 [PF14909.8, score=115.4]} {Human: ENSG00000132122, SPATA6, spermatogenesis associated 6, [RH, Score=105, Expect=4e-24]} {Mouse: ENSMUSG00000034401, Spata6, spermatogenesis associated 6, [RH, Score=99.0, Expect=4e-22]} {Smed: dd_Smed_v6_10543_0_1, dd_Smed_v6_10543_0_1, [Score=184, Expect=5e-55]} {RNA1509_28452, RNA1509_48064, RNA1509_8673} {RNA1310_20192, RNA1509_28452, RNA1509_48064} {RNA1509_28452, RNA1509_48064, RNA815_23278}

Mlig455_051366 {REF} {Length: 2585} {TRANSSPLICED} {Pfam: Spermatogenesis-assoc protein 6 [PF14909.8, score=114.8]} {Human: ENSG00000132122, SPATA6, spermatogenesis associated 6, [RH, Score=105, Expect=5e-24]} {Mouse: ENSMUSG00000034401, Spata6, spermatogenesis associated 6, [RH, Score=95.5, Expect=6e-21]} {Smed: dd_Smed_v6_10543_0_1, dd_Smed_v6_10543_0_1, [Score=184, Expect=6e-55]} {RNA1509_32010, RNA1509_32967, RNA1509_8673} {RNA1310_20192, RNA1509_32010, RNA1509_32967, RNA1509_8673} {RNA1509_32010, RNA1509_32967, RNA1509_8673, RNA815_17748}
6. MligTC455_30290 738 15.38 Mlig455_023808

Neo: -

Age: Up-Down-Up

 DST 2.586 - - 0.760 - 0.964 0.862 Mlig455_023808 {REF} {Length: 23754} {Pfam: Domain of unknown function (DUF1851) [PF08906.13, score=48.1]; D-amino acid oxidase activator [PF15199.8, score=40.8]; SH3 domain [PF17902.3, score=39.4]; Carbohydrate/starch-binding module (family 21) [PF03370.15, score=28.2]} {Human: ENSG00000151914, DST, dystonin, [RH, Score=74.7, Expect=2e-12]} {Mouse: ENSMUSG00000026131, Dst, dystonin, [RH, Score=73.6, Expect=4e-12]} {Dmel: FBgn0013733, shot, short stop, [Score=87.0, Expect=2e-16]} {Celegans: WBGene00006876, vab-10, VAB-10B protein, [Score=52.4, Expect=5e-06]} {Smed: dd_Smed_v6_8220_0_4, dd_Smed_v6_8220_0_4, [Score=160, Expect=4e-39]} {RNA1509_41993} {RNA1310_3340.2} {RNA815_578.1}
7. MligTC455_21640 262 5.46 Mlig455_052657

Neo: -

Age: -

 SLC6A5 2.576 - 0.755 - - 0.964 0.857 Mlig455_052657 {REF} {Length: 4833} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=583.6]; BTB/POZ domain [PF00651.33, score=59.5]; BTB And C-terminal Kelch [PF07707.17, score=44.3]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=24.7]; Protein of unknown function (DUF2722) [PF10846.10, score=18.1]} {Human: ENSG00000165970, SLC6A5, solute carrier family 6 member 5, [Score=316, Expect=2e-92]} {Mouse: ENSMUSG00000039728, Slc6a5, solute carrier family 6 (neurotransmitter transporter, glycine), member 5, [Score=315, Expect=5e-92]} {Dmel: FBgn0034911, CG5549, [Score=313, Expect=5e-89]} {Celegans: WBGene00000934, dat-1, Sodium-dependent dopamine transporter, [Score=228, Expect=2e-63]} {Smed: dd_Smed_v6_10458_0_1, dd_Smed_v6_10458_0_1, [Score=273, Expect=1e-78]} {RNA1509_27437} {RNA1310_7302.1} {RNA815_3821}
8. MligTC455_43786 401 8.35 Mlig455_054385

Neo: -

Age: -

 CCDC60 2.549 - 0.845 - 0.750 0.954 - Mlig455_054385 {REF} {Length: 3003} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4698) [PF15769.7, score=170.6]} {Human: ENSG00000183273, CCDC60, coiled-coil domain containing 60, [Score=62.8, Expect=2e-09]} {Mouse: ENSMUSG00000043913, Ccdc60, coiled-coil domain containing 60, [Score=62.4, Expect=1e-09]} {Smed: dd_Smed_v6_14286_0_1, dd_Smed_v6_14286_0_1, [Score=115, Expect=1e-26]} {RNA1509_58886} {RNA1310_1558.2} {RNA815_11153}
9. MligTC455_43741 196 4.08 Mlig455_018088

Neo: -

Age: Down-Up-Down

 PTBP1 2.519 - 0.760 0.807 - 0.952 - Mlig455_018088 {REF} {Length: 2775} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF13893.8, score=116.9]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=52.7]; Occluded RNA-recognition motif [PF16842.7, score=26.8]} {Human: ENSG00000011304, PTBP1, polypyrimidine tract binding protein 1, [Score=258, Expect=8e-80]; ENSG00000117569, PTBP2, polypyrimidine tract binding protein 2, [Score=258, Expect=1e-80]; ENSG00000119314, PTBP3, polypyrimidine tract binding protein 3, [Score=248, Expect=1e-76]} {Mouse: ENSMUSG00000028134, Ptbp2, polypyrimidine tract binding protein 2, [Score=258, Expect=7e-81]; ENSMUSG00000006498, Ptbp1, polypyrimidine tract binding protein 1, [Score=251, Expect=1e-78]; ENSMUSG00000028382, Ptbp3, polypyrimidine tract binding protein 3, [Score=248, Expect=1e-77]} {Dmel: FBgn0011224, heph, hephaestus, [Score=249, Expect=7e-78]} {Celegans: WBGene00004207, ptb-1, PTB (HnRNP) homolog; Putative RNA-binding protein PTB-1b, [Score=234, Expect=1e-72]} {Smed: dd_Smed_v6_1868_0_1, dd_Smed_v6_1868_0_1, [Score=214, Expect=4e-64]} {RNA1509_36451} {RNA1310_3345} {RNA815_23519}
10. MligTC455_21914 6688 139.34 Mlig455_041245, Mlig455_053092

Neo: -

Age: -

 FLNB 2.513 - - 0.745 0.785 0.983 -

Mlig455_041245 {REF} {Length: 5323} {Pfam: Filamin/ABP280 repeat [PF00630.21, score=341.5]} {Human: ENSG00000136068, FLNB, filamin B, [Score=238, Expect=1e-62]; ENSG00000196924, FLNA, filamin A, [Score=230, Expect=3e-60]} {Mouse: ENSMUSG00000031328, Flna, filamin, alpha, [Score=243, Expect=1e-64]} {Dmel: FBgn0028371, jbug, jitterbug, [RH, Score=429, Expect=2e-124]} {Celegans: WBGene00016006, fln-2, FiLamiN (Actin binding protein) homolog, [RH, Score=469, Expect=3e-139]} {Smed: dd_Smed_v6_14262_0_1, dd_Smed_v6_14262_0_1, [RH, Score=265, Expect=2e-73]} {RNA1509_1061} {RNA1310_1557.1, RNA1509_1061} {RNA1509_1061, RNA815_236}

Mlig455_053092 {REF} {Length: 4805} {Pfam: Filamin/ABP280 repeat [PF00630.21, score=342.0]} {Human: ENSG00000136068, FLNB, filamin B, [Score=239, Expect=4e-63]; ENSG00000196924, FLNA, filamin A, [Score=231, Expect=2e-60]} {Mouse: ENSMUSG00000031328, Flna, filamin, alpha, [Score=244, Expect=9e-65]} {Dmel: FBgn0028371, jbug, jitterbug, [RH, Score=430, Expect=1e-124]} {Celegans: WBGene00016006, fln-2, FiLamiN (Actin binding protein) homolog, [RH, Score=471, Expect=8e-140]} {Smed: dd_Smed_v6_14262_0_1, dd_Smed_v6_14262_0_1, [RH, Score=267, Expect=2e-74]} {RNA1509_1061} {RNA1310_1557.1} {RNA815_236}
11. MligTC455_41650 752 15.67 Mlig455_020540, Mlig455_020590, Mlig455_020592

Neo: -

Age: -

 ARMC9 2.507 - - 0.786 0.761 0.960 -

Mlig455_020540 {REF} {Length: 3118} {TRANSSPLICED} {Human: ENSG00000135931, ARMC9, armadillo repeat containing 9, [RH, Score=537, Expect=0.0]} {Mouse: ENSMUSG00000062590, Armc9, armadillo repeat containing 9, [RH, Score=533, Expect=3e-178]} {Smed: dd_Smed_v6_10926_0_1, dd_Smed_v6_10926_0_1, [RH, Score=498, Expect=8e-166]} {RNA1509_54977, RNA1509_9388} {RNA1310_10290, RNA1509_54977} {RNA1509_54977, RNA815_4141}

Mlig455_020590 {REF} {Length: 2939} {TRANSSPLICED} {Human: ENSG00000135931, ARMC9, armadillo repeat containing 9, [RH, Score=539, Expect=0.0]} {Mouse: ENSMUSG00000062590, Armc9, armadillo repeat containing 9, [RH, Score=531, Expect=8e-178]} {Smed: dd_Smed_v6_10926_0_1, dd_Smed_v6_10926_0_1, [RH, Score=499, Expect=3e-166]} {RNA1509_9388} {RNA1310_10290} {RNA815_4141}

Mlig455_020592 {REF} {Length: 1875} {Pfam: HEAT repeat [PF02985.24, score=19.7]} {Human: ENSG00000135931, ARMC9, armadillo repeat containing 9, [Score=227, Expect=3e-66]} {Mouse: ENSMUSG00000062590, Armc9, armadillo repeat containing 9, [Score=225, Expect=1e-65]} {Smed: dd_Smed_v6_10926_0_1, dd_Smed_v6_10926_0_1, [Score=219, Expect=4e-64]} {RNA1509_9388} {RNA1310_10290} {RNA815_4141}
12. MligTC455_43627 1683 35.07 Mlig455_012966

Neo: -

Age: -

 2.483 - - - 0.826 0.956 0.701 Mlig455_012966 {REF} {Length: 4640} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=231.1]} {Smed: dd_Smed_v6_19123_0_8, dd_Smed_v6_19123_0_8, [Score=73.9, Expect=2e-13]} {RNA1509_10570} {RNA1310_7155.1} {RNA815_1910.1}
13. MligTC455_49015 2886 60.13 Mlig455_019168

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.204

 PPP1R32 2.472 - 0.727 0.780 - 0.965 - Mlig455_019168 {REF} {Length: 1846} {TRANSSPLICED} {Pfam: Protein phosphatase 1 regulatory subunit 32 [PF15691.7, score=381.2]} {Human: ENSG00000162148, PPP1R32, protein phosphatase 1 regulatory subunit 32, [RH, Score=130, Expect=5e-33]} {Mouse: ENSMUSG00000035179, Ppp1r32, protein phosphatase 1, regulatory subunit 32, [RH, Score=150, Expect=2e-40]} {Smed: dd_Smed_v6_6404_0_1, dd_Smed_v6_6404_0_1, [RH, Score=263, Expect=2e-83]} {RNA1509_2656, RNA1509_42026, RNA1509_47496} {RNA1310_15371.1, RNA1509_2656, RNA1509_42026, RNA1509_47496} {RNA1509_2656, RNA1509_42026, RNA1509_47496, RNA815_5915}
14. MligTC455_20009 4606 95.96 Mlig455_038152, Mlig455_038257

Neo: -

Age: -

Region-enriched R4: 1.035/0.02931

 2.445 - - 0.720 0.768 0.957 -

Mlig455_038152 {REF} {Length: 1064} {Smed: dd_Smed_v6_8141_0_1, dd_Smed_v6_8141_0_1, [RH, Score=94.7, Expect=3e-26]} {RNA1509_10830, RNA1509_16892} {RNA1310_37711, RNA1509_10830} {RNA1509_10830, RNA815_18837}

Mlig455_038257 {REF} {Length: 2711} {Smed: dd_Smed_v6_8141_0_1, dd_Smed_v6_8141_0_1, [RH, Score=94.7, Expect=3e-26]} {RNA1509_16892, RNA1509_40689} {RNA1310_37711, RNA1509_16892, RNA1509_40689} {RNA1509_16892, RNA1509_40689, RNA815_18837}
15. MligTC455_43063 5711 118.98 Mlig455_008727, Mlig455_063588, Mlig455_063597

Neo: -

Age: logFC(26M/2M)=-0.428

Region-enriched R8: 1.085/0.01787

 GGT1 1.906 - - - 0.944 0.962 -

Mlig455_008727 {REF} {Length: 2577} {Pfam: Gamma-glutamyltranspeptidase [PF01019.23, score=528.5]} {Human: ENSG00000100031, GGT1, gamma-glutamyltransferase 1, [RH, Score=419, Expect=8e-139]} {Mouse: ENSMUSG00000006345, Ggt1, gamma-glutamyltransferase 1, [RH, Score=392, Expect=2e-128]} {Dmel: FBgn0025837, CG17636, [RH, Score=352, Expect=7e-113]} {Celegans: WBGene00016906, C53D5.5, [RH, Score=387, Expect=6e-126]} {Smed: dd_Smed_v6_4591_0_1, dd_Smed_v6_4591_0_1, [RH, Score=443, Expect=7e-148]} {RNA1509_10553, RNA1509_2471, RNA1509_29196} {RNA1310_8769, RNA1509_10553, RNA1509_29196} {RNA1509_10553, RNA1509_29196, RNA815_2837}

Mlig455_063588 {REF} {Length: 2595} {Pfam: Gamma-glutamyltranspeptidase [PF01019.23, score=502.5]} {Human: ENSG00000100031, GGT1, gamma-glutamyltransferase 1, [RH, Score=409, Expect=1e-136]} {Mouse: ENSMUSG00000006345, Ggt1, gamma-glutamyltransferase 1, [Score=381, Expect=5e-126]} {Dmel: FBgn0025837, CG17636, [RH, Score=348, Expect=4e-113]} {Celegans: WBGene00016906, C53D5.5, [Score=357, Expect=3e-116]} {Smed: dd_Smed_v6_4591_0_2, dd_Smed_v6_4591_0_2, [RH, Score=402, Expect=5e-134]} {RNA1509_2471} {RNA1310_8769} {RNA815_2837}

Mlig455_063597 {REF} {Length: 2607} {Pfam: Gamma-glutamyltranspeptidase [PF01019.23, score=527.1]} {Human: ENSG00000100031, GGT1, gamma-glutamyltransferase 1, [RH, Score=417, Expect=4e-139]} {Mouse: ENSMUSG00000006345, Ggt1, gamma-glutamyltransferase 1, [Score=389, Expect=3e-128]} {Dmel: FBgn0025837, CG17636, [RH, Score=351, Expect=2e-113]} {Celegans: WBGene00016906, C53D5.5, [RH, Score=386, Expect=3e-126]} {Smed: dd_Smed_v6_4591_0_1, dd_Smed_v6_4591_0_1, [RH, Score=443, Expect=4e-149]} {RNA1509_2471, RNA1509_44409} {RNA1310_8769, RNA1509_44409} {RNA1509_44409, RNA815_2837}
16. MligTC455_53778 951 19.82 Mlig455_007965, Mlig455_015595

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.392

Region-enriched R4: 2.645/0.00192

 PRXL2C 1.854 - - - 0.891 0.963 -

Mlig455_007965 {REF} {Length: 1357} {Pfam: AhpC/TSA antioxidant enzyme [PF13911.8, score=24.2]} {Smed: dd_Smed_v6_4424_0_1, dd_Smed_v6_4424_0_1, [Score=108, Expect=6e-30]} {RNA1509_57652} {RNA1310_27001.1} {RNA815_11622}

Mlig455_015595 {REF} {Length: 1838} {Pfam: AhpC/TSA antioxidant enzyme [PF13911.8, score=40.9]} {Human: ENSG00000158122, PRXL2C, peroxiredoxin like 2C, [RH, Score=135, Expect=5e-39]} {Mouse: ENSMUSG00000021482, Aaed1, AhpC/TSA antioxidant enzyme domain containing 1, [Score=125, Expect=3e-35]} {Smed: dd_Smed_v6_4424_0_1, dd_Smed_v6_4424_0_1, [RH, Score=149, Expect=3e-45]} {RNA1509_57652} {RNA1310_27001.2, RNA1509_57652} {RNA1509_57652, RNA815_11622}
17. MligTC455_46426 2278 47.46 Mlig455_028820

Neo: -

Age: -

 1.842 - - - 0.890 0.952 - Mlig455_028820 {REF} {Length: 1179} {RNA1509_54782} {RNA1310_7508} {RNA815_176.1}
18. MligTC455_53211 1358 28.3 Mlig455_040065, Mlig455_040091

Neo: -

Age: logFC(26M/2M)=-0.362

Region-enriched R4: 1.888/0.01442

 1.825 - - - 0.874 0.951 -

Mlig455_040065 {REF} {Length: 3189} {RNA1509_49542, RNA1509_9168} {RNA1310_8796.1, RNA1509_49542, RNA1509_9168} {RNA1509_49542, RNA1509_9168, RNA815_3100}

Mlig455_040091 {REF} {Length: 2759} {RNA1509_39791, RNA1509_9168} {RNA1310_8796.1, RNA1509_39791} {RNA1509_39791, RNA815_3100}
19. MligTC455_40861 5298 110.38 Mlig455_009208

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.204

 STOM 1.813 - - 0.862 - 0.951 - Mlig455_009208 {REF} {Length: 1586} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=118.4]; SPFH domain-Band 7 family [PF13421.8, score=20.1]} {Human: ENSG00000148175, STOM, stomatin, [Score=251, Expect=2e-82]; ENSG00000133115, STOML3, stomatin like 3, [Score=241, Expect=2e-78]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [Score=248, Expect=2e-81]} {Dmel: FBgn0260657, CG42540, [Score=261, Expect=3e-85]} {Celegans: WBGene00006063, sto-1, Stomatin-1, [Score=261, Expect=4e-86]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [Score=291, Expect=1e-98]} {RNA1509_21648} {RNA1310_25287.1} {RNA815_14054.1}
20. MligTC455_24058 874 18.21 Mlig455_049588

Neo: -

Age: logFC(26M/2M)=0.283

 SYTL4 1.801 - - 0.836 - 0.965 - Mlig455_049588 {REF} {Length: 12642} {TRANSSPLICED} {Pfam: C2 domain [PF00168.32, score=68.1]; FYVE-type zinc finger [PF02318.18, score=53.4]; Protein of unknown function (DUF3139) [PF11337.10, score=20.6]} {Human: ENSG00000102362, SYTL4, synaptotagmin like 4, [Score=100, Expect=3e-20]; ENSG00000147041, SYTL5, synaptotagmin like 5, [Score=99.0, Expect=1e-19]} {Mouse: ENSMUSG00000031255, Sytl4, synaptotagmin-like 4, [Score=100, Expect=3e-20]} {Dmel: FBgn0266756, btsz, bitesize, [Score=117, Expect=2e-25]} {Celegans: WBGene00004923, snt-3, SyNapTotagmin, [Score=57.8, Expect=5e-08]} {Smed: dd_Smed_v6_4335_0_1, dd_Smed_v6_4335_0_1, [Score=84.7, Expect=5e-16]} {RNA1509_12528, RNA1509_2527} {RNA1310_245.3, RNA1509_12528} {RNA1509_12528, RNA815_559.1}
21. MligTC455_33802 659 13.73 Mlig455_033383

Neo: -

Age: logFC(26M/2M)=-0.359

 1.798 - - - 0.837 0.961 - Mlig455_033383 {REF} {Length: 3524} {RNA1509_14410, RNA1509_56133} {RNA1310_8398, RNA1509_56133} {RNA1509_56133, RNA815_14639}
22. MligTC455_51903 1283 26.73 Mlig455_021657, Mlig455_067458

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.872

 CHRNB1, CHRNB3 1.79 - - - 0.822 0.968 -

Mlig455_021657 {REF} {Length: 2044} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=147.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=73.5]} {Human: ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=193, Expect=5e-56]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=189, Expect=1e-54]} {Mouse: ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=187, Expect=8e-54]; ENSMUSG00000035594, Chrna5, cholinergic receptor, nicotinic, alpha polypeptide 5, [Score=186, Expect=1e-53]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=179, Expect=5e-51]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [Score=176, Expect=3e-49]} {Celegans: WBGene00006774, unc-38, Acetylcholine receptor subunit alpha-type unc-38, [Score=174, Expect=9e-49]} {Smed: dd_Smed_v6_2019_0_1, dd_Smed_v6_2019_0_1, [Score=346, Expect=9e-116]} {RNA1509_8724} {RNA1310_17144.1, RNA1509_8724} {RNA1509_8724, RNA815_6285}

Mlig455_067458 {REF} {Length: 1512} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=43.5]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=18.7]} {Human: ENSG00000283946, CHRNB1, cholinergic receptor nicotinic beta 1 subunit, [Score=48.1, Expect=7e-06]; ENSG00000170175, CHRNB1, cholinergic receptor nicotinic beta 1 subunit, [Score=48.1, Expect=7e-06]; ENSG00000117971, CHRNB4, cholinergic receptor nicotinic beta 4 subunit, [Score=47.8, Expect=1e-05]} {Mouse: ENSMUSG00000029205, Chrna9, cholinergic receptor, nicotinic, alpha polypeptide 9, [Score=47.4, Expect=1e-05]} {Celegans: WBGene00000055, acr-16, Acetylcholine receptor subunit alpha-type acr-16, [Score=46.6, Expect=1e-05]} {Smed: dd_Smed_v6_2019_0_1, dd_Smed_v6_2019_0_1, [Score=96.7, Expect=1e-22]} {RNA1509_8724} {RNA1310_17144.1} {RNA815_6285}
23. MligTC455_46559 1484 30.91 Mlig455_056465

Neo: -

Age: logFC(26M/2M)=-0.295

 TANC1 1.774 - - - 0.808 0.966 - Mlig455_056465 {REF} {Length: 2067} {Pfam: Ankyrin repeats (many copies) [PF13857.8, score=50.7]; Ankyrin repeats (3 copies) [PF12796.9, score=48.4]; Ankyrin repeat [PF13606.8, score=41.8]; Ankyrin repeats (many copies) [PF13637.8, score=41.1]; Ankyrin repeat [PF00023.32, score=36.6]} {Human: ENSG00000115183, TANC1, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1, [Score=57.0, Expect=5e-08]; ENSG00000145362, ANK2, ankyrin 2, [Score=57.0, Expect=5e-08]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=55.8, Expect=9e-08]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=58.2, Expect=1e-08]} {Smed: dd_Smed_v6_13251_0_1, dd_Smed_v6_13251_0_1, [Score=53.1, Expect=1e-07]} {RNA1509_19702, RNA1509_36019, RNA1509_36843, RNA1509_6963} {RNA1310_14830, RNA1509_36019, RNA1509_36843, RNA1509_6963} {RNA1509_36019, RNA1509_36843, RNA1509_6963, RNA815_5101}
24. MligTC455_20230 1282 26.71 Mlig455_003493, Mlig455_015562

Neo: -

Age: logFC(26M/2M)=-0.236

 FAM227A, FAM227B 1.771 - - - 0.803 0.968 -

Mlig455_003493 {REF} {Length: 2231} {TRANSSPLICED} {Pfam: Protein of unknown function [PF14922.8, score=146.0]} {Human: ENSG00000184949, FAM227A, family with sequence similarity 227 member A, [Score=111, Expect=2e-25]} {Mouse: ENSMUSG00000042564, Fam227a, family with sequence similarity 227, member A, [RH, Score=96.7, Expect=8e-21]; ENSMUSG00000027209, Fam227b, family with sequence similarity 227, member B, [RH, Score=93.6, Expect=6e-20]} {Smed: dd_Smed_v6_15102_0_3, dd_Smed_v6_15102_0_3, [Score=157, Expect=3e-42]} {RNA1509_44428} {RNA1310_6983.2} {RNA815_5876}

Mlig455_015562 {REF} {Length: 2171} {TRANSSPLICED} {Pfam: Protein of unknown function [PF14922.8, score=146.7]} {Human: ENSG00000166262, FAM227B, family with sequence similarity 227 member B, [RH, Score=107, Expect=2e-24]} {Mouse: ENSMUSG00000027209, Fam227b, family with sequence similarity 227, member B, [RH, Score=98.6, Expect=1e-21]} {Smed: dd_Smed_v6_15102_0_7, dd_Smed_v6_15102_0_7, [Score=178, Expect=5e-50]} {RNA1509_58462} {RNA1310_11701} {RNA815_12354}
25. MligTC455_32850 737 15.36 Mlig455_026517

Neo: -

Age: -

 1.769 - - - 0.809 - 0.960 Mlig455_026517 {REF} {Length: 2652} {Pfam: Plectin repeat [PF00681.22, score=24.6]} {RNA1509_45383, RNA1509_45883} {RNA1310_7758.2, RNA1509_45383} {RNA1509_45383, RNA815_9451}
26. MligTC455_30801 483 10.05 Mlig455_027631, Mlig455_027642

Neo: -

Age: Up-Down-Down

Region-enriched R4: 2.277/0.03108

 TRPM7 1.759 - - 0.806 - 0.953 -

Mlig455_027631 {REF} {Length: 3904} {Pfam: Ion transport protein [PF00520.33, score=35.0]} {Human: ENSG00000092439, TRPM7, transient receptor potential cation channel subfamily M member 7, [Score=79.0, Expect=3e-14]} {Mouse: ENSMUSG00000027365, Trpm7, transient receptor potential cation channel, subfamily M, member 7, [Score=73.9, Expect=5e-13]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=81.6, Expect=2e-15]} {Celegans: WBGene00001651, gon-2, Transient receptor potential channel, [Score=70.5, Expect=3e-12]} {Smed: dd_Smed_v6_26251_0_1, dd_Smed_v6_26251_0_1, [Score=100, Expect=1e-21]} {RNA1509_8759} {RNA1310_4330.3, RNA1509_8759} {RNA1509_8759, RNA815_1383.1}

Mlig455_027642 {REF} {Length: 4185} {Pfam: Ion transport protein [PF00520.33, score=35.0]} {Human: ENSG00000092439, TRPM7, transient receptor potential cation channel subfamily M member 7, [Score=76.3, Expect=1e-13]} {Mouse: ENSMUSG00000027365, Trpm7, transient receptor potential cation channel, subfamily M, member 7, [Score=71.6, Expect=3e-12]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=81.3, Expect=2e-15]} {Celegans: WBGene00001651, gon-2, Transient receptor potential channel, [Score=70.5, Expect=3e-12]} {Smed: dd_Smed_v6_26251_0_1, dd_Smed_v6_26251_0_1, [Score=100, Expect=1e-21]} {RNA1509_8759} {RNA1310_3171.2} {RNA815_1383.1}
27. MligTC455_51902 1049 21.85 Mlig455_021705

Neo: -

Age: logFC(26M/2M)=-0.488

 CHRNB3 1.753 - - - 0.779 0.974 - Mlig455_021705 {REF} {Length: 1861} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=147.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=72.7]} {Human: ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=191, Expect=2e-55]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=189, Expect=2e-54]; ENSG00000169684, CHRNA5, cholinergic receptor nicotinic alpha 5 subunit, [Score=182, Expect=6e-52]} {Mouse: ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=186, Expect=2e-53]; ENSMUSG00000035594, Chrna5, cholinergic receptor, nicotinic, alpha polypeptide 5, [Score=185, Expect=2e-53]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=182, Expect=4e-52]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [Score=177, Expect=2e-49]} {Celegans: WBGene00006774, unc-38, Acetylcholine receptor subunit alpha-type unc-38, [Score=174, Expect=7e-49]} {Smed: dd_Smed_v6_2019_0_1, dd_Smed_v6_2019_0_1, [Score=347, Expect=6e-116]} {RNA1509_8724} {RNA1310_17144.1} {RNA815_6285}
28. MligTC455_44623 3349 69.77 Mlig455_040692, Mlig455_064561

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.362

 1.75 - - 0.797 - 0.953 -

Mlig455_040692 {REF} {Length: 1243} {Pfam: Domain of unknown function (DUF4476) [PF14771.8, score=37.3]} {Smed: dd_Smed_v6_50605_0_1, dd_Smed_v6_50605_0_1, [RH, Score=197, Expect=4e-63]} {RNA1509_7167} {RNA1310_27037, RNA1509_7167} {RNA1509_7167, RNA815_11150}

Mlig455_064561 {REF} {Length: 1230} {Pfam: Domain of unknown function (DUF4476) [PF14771.8, score=37.3]} {Smed: dd_Smed_v6_50605_0_1, dd_Smed_v6_50605_0_1, [RH, Score=197, Expect=4e-63]} {RNA1509_59684, RNA1509_7167} {RNA1310_27037, RNA1509_59684} {RNA1509_59684, RNA815_11150}
29. MligTC455_52239 629 13.1 Mlig455_029233

Neo: -

Age: logFC(26M/2M)=-0.429

 ABCG2 1.747 - - - 0.778 0.969 - Mlig455_029233 {REF} {Length: 3918} {Pfam: ABC-2 type transporter [PF01061.26, score=125.2]; ABC transporter [PF00005.29, score=73.3]; ABC-2 type transporter [PF19055.2, score=43.6]; AAA domain, putative AbiEii toxin, Type IV TA system [PF13304.8, score=31.5]; RecF/RecN/SMC N terminal domain [PF02463.21, score=23.9]; AAA domain [PF13476.8, score=20.9]} {Human: ENSG00000118777, ABCG2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=541, Expect=0.0]} {Mouse: ENSMUSG00000029802, Abcg2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=546, Expect=0.0]} {Dmel: FBgn0003996, w, white, [Score=257, Expect=4e-74]} {Celegans: WBGene00012925, wht-8, WHiTe (Drosophila) related ABC transporter, [RH, Score=259, Expect=1e-75]} {Smed: dd_Smed_v6_4225_0_2, dd_Smed_v6_4225_0_2, [RH, Score=689, Expect=0.0]} {RNA1509_2851} {RNA1310_949.2} {RNA815_1895}
30. MligTC455_54177 858 17.88 Mlig455_020727

Neo: -

Age: Down-Down-Up

Region-enriched R8: 2.370/0.00010
Region-enriched R7: 2.006/0.00008

 1.743 - - - 0.757 0.986 - Mlig455_020727 {REF} {Length: 2702} {Smed: dd_Smed_v6_5057_0_1, dd_Smed_v6_5057_0_1, [RH, Score=91.7, Expect=4e-20]} {RNA1509_10580} {RNA1310_9366} {RNA815_2566}
31. MligTC455_39612 861 17.93 Mlig455_019206

Neo: -

Age: logFC(26M/2M)=-0.343

 DLEC1 1.725 - - - 0.768 0.957 - Mlig455_019206 {REF} {Length: 7152} {TRANSSPLICED} {Pfam: Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin [PF15780.7, score=68.8]; Flagellar-associated PapD-like [PF14874.8, score=25.0]} {Human: ENSG00000008226, DLEC1, DLEC1, cilia and flagella associated protein, [RH, Score=721, Expect=0.0]} {Mouse: ENSMUSG00000038060, Dlec1, deleted in lung and esophageal cancer 1, [RH, Score=725, Expect=0.0]} {Smed: dd_Smed_v6_10833_0_1, dd_Smed_v6_10833_0_1, [RH, Score=813, Expect=0.0]} {RNA1509_3454} {RNA1310_859.1, RNA1509_3454} {RNA1509_3454, RNA815_262}
32. MligTC455_21803 1070 22.29 Mlig455_051085

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.341

 1.724 - - 0.760 - 0.964 - Mlig455_051085 {REF} {Length: 13899} {TRANSSPLICED} {Smed: dd_Smed_v6_4420_0_2, dd_Smed_v6_4420_0_2, [Score=53.1, Expect=3e-06]} {RNA1509_25269} {RNA1310_284.1} {RNA815_96}
33. MligTC455_40437 142 2.96 Mlig455_007644

Neo: -

Age: logFC(26M/2M)=-0.263

 1.713 - - - 0.759 0.954 - Mlig455_007644 {REF} {Length: 3098} {TRANSSPLICED} {Pfam: Fasciclin domain [PF02469.24, score=126.6]} {Dmel: FBgn0260745, mfas, midline fasciclin, [Score=50.4, Expect=5e-06]} {Celegans: WBGene00009162, F26E4.7, [RH, Score=67.4, Expect=2e-11]} {RNA1509_10760} {RNA1310_4612.1} {RNA815_1343.1}
34. MligTC455_45835 2142 44.62 Mlig455_031421, Mlig455_056470

Neo: -

Age: -

 MAPK15 1.706 - - 0.756 - 0.950 -

Mlig455_031421 {REF} {Length: 3734} {Pfam: Protein kinase domain [PF00069.27, score=230.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.8]} {Human: ENSG00000274205, MAPK15, mitogen-activated protein kinase 15, [RH, Score=482, Expect=1e-163]; ENSG00000181085, MAPK15, mitogen-activated protein kinase 15, [RH, Score=482, Expect=1e-163]} {Mouse: ENSMUSG00000063704, Mapk15, mitogen-activated protein kinase 15, [RH, Score=475, Expect=4e-161]} {Dmel: FBgn0052703, Erk7, Extracellularly regulated kinase 7, [RH, Score=431, Expect=2e-139]} {Celegans: WBGene00015478, mapk-15, Putative serine/threonine-protein kinase C05D10.2, [RH, Score=498, Expect=2e-171]} {Smed: dd_Smed_v6_11396_0_1, dd_Smed_v6_11396_0_1, [RH, Score=535, Expect=0.0]} {RNA1509_9258} {RNA1310_16008} {RNA815_26216}

Mlig455_056470 {REF} {Length: 4231} {Pfam: Protein kinase domain [PF00069.27, score=229.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.3]} {Human: ENSG00000274205, MAPK15, mitogen-activated protein kinase 15, [RH, Score=480, Expect=3e-162]; ENSG00000181085, MAPK15, mitogen-activated protein kinase 15, [RH, Score=480, Expect=3e-162]} {Mouse: ENSMUSG00000063704, Mapk15, mitogen-activated protein kinase 15, [RH, Score=474, Expect=7e-160]} {Dmel: FBgn0052703, Erk7, Extracellularly regulated kinase 7, [RH, Score=430, Expect=2e-138]} {Celegans: WBGene00015478, mapk-15, Putative serine/threonine-protein kinase C05D10.2, [RH, Score=498, Expect=5e-171]} {Smed: dd_Smed_v6_11396_0_1, dd_Smed_v6_11396_0_1, [RH, Score=534, Expect=1e-179]} {RNA1509_9258} {RNA1310_16008} {RNA815_26216}
35. MligTC455_39608 6604 137.59 Mlig455_023921, Mlig455_046482

Neo: -

Age: -

 APP 1.701 - - - 0.733 0.968 -

Mlig455_023921 {REF} {Length: 3702} {TRANSSPLICED} {Pfam: Amyloid A4 N-terminal heparin-binding [PF02177.18, score=48.7]; E2 domain of amyloid precursor protein [PF12925.9, score=43.8]; Beta-amyloid precursor protein C-terminus [PF10515.11, score=40.8]; Copper-binding of amyloid precursor, CuBD [PF12924.9, score=39.1]} {Human: ENSG00000142192, APP, amyloid beta precursor protein, [Score=84.3, Expect=3e-16]} {Mouse: ENSMUSG00000022892, App, amyloid beta (A4) precursor protein, [Score=84.0, Expect=3e-16]} {Dmel: FBgn0000108, Appl, beta amyloid protein precursor-like, [Score=85.9, Expect=6e-17]} {Celegans: WBGene00000149, apl-1, Beta-amyloid-like protein, [RH, Score=101, Expect=4e-22]} {Smed: dd_Smed_v6_2561_0_1, dd_Smed_v6_2561_0_1, [RH, Score=134, Expect=7e-33]} {RNA1509_11651, RNA1509_19546, RNA1509_2244, RNA1509_31480, RNA1509_4900} {RNA1310_3149.1, RNA1509_11651, RNA1509_19546, RNA1509_2244, RNA1509_31480, RNA1509_4900} {RNA1509_11651, RNA1509_19546, RNA1509_2244, RNA1509_31480, RNA1509_4900, RNA815_958.1}

Mlig455_046482 {REF} {Length: 3710} {TRANSSPLICED} {Pfam: Amyloid A4 N-terminal heparin-binding [PF02177.18, score=47.8]; E2 domain of amyloid precursor protein [PF12925.9, score=43.1]; Beta-amyloid precursor protein C-terminus [PF10515.11, score=40.8]; Copper-binding of amyloid precursor, CuBD [PF12924.9, score=39.2]} {Human: ENSG00000142192, APP, amyloid beta precursor protein, [Score=84.7, Expect=2e-16]} {Mouse: ENSMUSG00000022892, App, amyloid beta (A4) precursor protein, [Score=84.3, Expect=2e-16]} {Dmel: FBgn0000108, Appl, beta amyloid protein precursor-like, [Score=85.5, Expect=9e-17]} {Celegans: WBGene00000149, apl-1, Beta-amyloid-like protein, [RH, Score=103, Expect=9e-23]} {Smed: dd_Smed_v6_2561_0_1, dd_Smed_v6_2561_0_1, [RH, Score=138, Expect=3e-34]} {RNA1509_11651, RNA1509_35488} {RNA1310_3149.1, RNA1509_35488} {RNA1509_35488, RNA815_958.1}
36. MligTC455_39145 860 17.92 Mlig455_045710

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.035/0.04635

 1.692 - - - 0.742 0.950 - Mlig455_045710 {REF} {Length: 2657} {Pfam: Family of unknown function (DUF5580) [PF17743.3, score=80.4]} {Smed: dd_Smed_v6_9326_0_1, dd_Smed_v6_9326_0_1, [RH, Score=180, Expect=1e-49]} {RNA1509_11160, RNA1509_32698} {RNA1310_8387, RNA1509_11160, RNA1509_32698} {RNA1509_11160, RNA1509_32698, RNA815_15696.1}
37. MligTC455_53471 1325 27.61 Mlig455_015629

Neo: -

Age: logFC(26M/2M)=-0.386

 CFAP65 1.689 - - 0.738 - 0.951 - Mlig455_015629 {REF} {Length: 5817} {Pfam: Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin [PF15780.7, score=93.0]; MSP (Major sperm protein) domain [PF00635.28, score=47.3]; Protein of unknown function (DUF1573) [PF07610.13, score=22.4]; Transmembrane protein 131-like N-terminal [PF12371.10, score=21.0]} {Human: ENSG00000181378, CFAP65, cilia and flagella associated protein 65, [RH, Score=850, Expect=0.0]} {Mouse: ENSMUSG00000047021, Cfap65, cilia and flagella associated protein 65, [RH, Score=844, Expect=0.0]} {Smed: dd_Smed_v6_12428_0_1, dd_Smed_v6_12428_0_1, [RH, Score=1276, Expect=0.0]} {RNA1509_19700} {RNA1310_760, RNA1509_19700} {RNA1509_19700, RNA815_222.1}
38. MligTC455_28901 2683 55.89 Mlig455_000702, Mlig455_000756

Neo: -

Age: -

 CNTRL 1.679 - - - - 0.970 0.709

Mlig455_000702 {REF} {Length: 7735} {TRANSSPLICED} {Pfam: Leucine-rich repeat [PF14580.8, score=68.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=62.9]; Leucine rich repeat [PF13855.8, score=47.3]; Crescentin protein [PF19220.2, score=23.5]} {Human: ENSG00000119397, CNTRL, centriolin, [Score=217, Expect=9e-56]} {Mouse: ENSMUSG00000057110, Cntrl, centriolin, [Score=217, Expect=7e-56]} {Dmel: FBgn0032163, TbCMF46, [Score=85.5, Expect=3e-16]} {Celegans: WBGene00015516, C06A8.6, [Score=78.2, Expect=1e-14]} {Smed: dd_Smed_v6_10369_0_1, dd_Smed_v6_10369_0_1, [Score=189, Expect=6e-48]} {RNA1509_7114} {RNA1310_12566} {RNA815_3884}

Mlig455_000756 {REF} {Length: 7584} {TRANSSPLICED} {Pfam: Leucine-rich repeat [PF14580.8, score=65.5]; Leucine Rich repeats (2 copies) [PF12799.9, score=61.9]; Leucine rich repeat [PF13855.8, score=45.8]} {Human: ENSG00000119397, CNTRL, centriolin, [RH, Score=254, Expect=4e-67]} {Mouse: ENSMUSG00000057110, Cntrl, centriolin, [RH, Score=257, Expect=4e-68]} {Dmel: FBgn0032163, TbCMF46, [Score=84.7, Expect=4e-16]} {Celegans: WBGene00015516, C06A8.6, [Score=78.2, Expect=1e-14]} {Smed: dd_Smed_v6_10369_0_1, dd_Smed_v6_10369_0_1, [RH, Score=199, Expect=9e-51]} {RNA1509_40686, RNA1509_7114} {RNA1310_1213, RNA1509_40686} {RNA1509_40686, RNA815_4518}
39. MligTC455_49002 1240 25.84 Mlig455_023460

Neo: -

Age: -

 1.672 - - 0.715 - 0.957 - Mlig455_023460 {REF} {Length: 3425} {Pfam: Cupin-like domain [PF13621.8, score=42.3]} {Dmel: FBgn0038510, CG14331, [Score=164, Expect=4e-48]} {Celegans: WBGene00004205, psr-1, Bifunctional arginine demethylase and lysyl-hydroxylase psr-1, [Score=57.8, Expect=3e-09]} {Smed: dd_Smed_v6_8235_0_1, dd_Smed_v6_8235_0_1, [Score=163, Expect=2e-47]} {RNA1509_22854} {RNA1310_16345.2, RNA1509_22854} {RNA1509_22854, RNA815_11283}
40. MligTC455_36816 362 7.54 Mlig455_027841, Mlig455_060008

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.712

 ANK3 1.671 - - - - 0.958 0.713

Mlig455_027841 {REF} {Length: 5725} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=91.6]; Protein of unknown function (DUF3421) [PF11901.10, score=84.7]; Ankyrin repeats (many copies) [PF13637.8, score=72.1]; Ankyrin repeats (many copies) [PF13857.8, score=49.2]; Ankyrin repeat [PF13606.8, score=41.0]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=55.5, Expect=1e-06]} {Mouse: ENSMUSG00000052331, Ankrd44, ankyrin repeat domain 44, [Score=62.4, Expect=5e-09]} {Dmel: FBgn0034583, CG10527, [Score=93.6, Expect=3e-20]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=81.3, Expect=5e-15]} {Smed: dd_Smed_v6_766_0_1, dd_Smed_v6_766_0_1, [Score=118, Expect=2e-30]} {RNA1509_30268} {RNA1310_2381} {RNA815_861}

Mlig455_060008 {REF} {Length: 4931} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=93.3]; Ankyrin repeats (many copies) [PF13637.8, score=74.1]; Ankyrin repeats (many copies) [PF13857.8, score=51.3]; Ankyrin repeat [PF13606.8, score=43.0]; Ankyrin repeat [PF00023.32, score=19.4]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=53.5, Expect=3e-06]} {Mouse: ENSMUSG00000052331, Ankrd44, ankyrin repeat domain 44, [Score=61.2, Expect=8e-09]} {Dmel: FBgn0016920, nompC, no mechanoreceptor potential C, [Score=52.0, Expect=5e-06]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=80.5, Expect=8e-15]} {Smed: dd_Smed_v6_13721_0_1, dd_Smed_v6_13721_0_1, [Score=59.3, Expect=1e-08]} {RNA1509_30268} {RNA1310_2381} {RNA815_861}
41. MligTC455_51954 1404 29.25 Mlig455_038586

Neo: -

Age: -

 1.67 - 0.718 - - 0.952 - Mlig455_038586 {REF} {Length: 2052} {Pfam: Wnt and FGF inhibitory regulator [PF13908.8, score=19.1]} {RNA1509_11900, RNA1509_20653} {RNA1310_15381, RNA1509_11900, RNA1509_20653} {RNA1509_11900, RNA1509_20653, RNA815_5778}
42. MligTC455_44971 99 2.07 Mlig455_055696

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.674

Region-enriched R4: 4.753/0.00442

 ATP1B1 1.66 - - - 0.707 0.953 - Mlig455_055696 {REF} {Length: 2498} {TRANSSPLICED} {Pfam: Sodium / potassium ATPase beta chain [PF00287.20, score=206.1]} {Human: ENSG00000143153, ATP1B1, ATPase Na+/K+ transporting subunit beta 1, [RH, Score=125, Expect=7e-33]} {Mouse: ENSMUSG00000026576, Atp1b1, ATPase, Na+/K+ transporting, beta 1 polypeptide, [RH, Score=127, Expect=8e-34]} {Dmel: FBgn0032946, nrv3, nervana 3, [RH, Score=164, Expect=8e-48]} {Celegans: WBGene00007646, nkb-1, Sodium/potassium-transporting ATPase subunit beta-1, [Score=151, Expect=4e-43]} {Smed: dd_Smed_v6_7917_0_1, dd_Smed_v6_7917_0_1, [RH, Score=244, Expect=2e-79]} {RNA1509_10526} {RNA1310_27937} {RNA815_16874}
43. MligTC455_52942 1583 32.98 Mlig455_016027

Neo: -

Age: Down-Up-Down

 PNPT1 0.972 - - - - 0.972 - Mlig455_016027 {REF} {Length: 2518} {Pfam: Ligand-gated ion channel [PF00060.28, score=20.1]} {Human: ENSG00000138035, PNPT1, polyribonucleotide nucleotidyltransferase 1, [RH, Score=53.1, Expect=3e-07]} {Mouse: ENSMUSG00000020464, Pnpt1, polyribonucleotide nucleotidyltransferase 1, [RH, Score=54.7, Expect=5e-08]} {Smed: dd_Smed_v6_8233_0_1, dd_Smed_v6_8233_0_1, [Score=47.4, Expect=6e-06]} {RNA1509_45927} {RNA1310_3249} {RNA815_1535.1}
44. MligTC455_52943 3134 65.28 Mlig455_054948, Mlig455_054962

Neo: -

Age: -

 GRIK5 0.969 - - - - 0.969 -

Mlig455_054948 {REF} {Length: 3322} {Pfam: Ligand-gated ion channel [PF00060.28, score=71.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=56.0]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=44.7]} {Human: ENSG00000105737, GRIK5, glutamate ionotropic receptor kainate type subunit 5, [Score=118, Expect=1e-26]} {Mouse: ENSMUSG00000003378, Grik5, glutamate receptor, ionotropic, kainate 5 (gamma 2), [Score=119, Expect=6e-27]} {Dmel: FBgn0038837, CG3822, [Score=127, Expect=8e-30]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=115, Expect=6e-26]} {Smed: dd_Smed_v6_10048_0_1, dd_Smed_v6_10048_0_1, [RH, Score=107, Expect=1e-23]} {RNA1509_35543, RNA1509_3983} {RNA1310_4551, RNA1509_35543} {RNA1509_35543, RNA815_1535.1}

Mlig455_054962 {REF} {Length: 4559} {Pfam: Ligand-gated ion channel [PF00060.28, score=71.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=56.0]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=44.7]} {Human: ENSG00000105737, GRIK5, glutamate ionotropic receptor kainate type subunit 5, [Score=118, Expect=1e-26]} {Mouse: ENSMUSG00000003378, Grik5, glutamate receptor, ionotropic, kainate 5 (gamma 2), [Score=119, Expect=6e-27]} {Dmel: FBgn0038837, CG3822, [Score=127, Expect=9e-30]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=115, Expect=6e-26]} {Smed: dd_Smed_v6_10048_0_1, dd_Smed_v6_10048_0_1, [RH, Score=107, Expect=1e-23]} {RNA1509_3983} {RNA1310_4551, RNA1509_3983} {RNA1509_3983, RNA815_1535.1}
45. MligTC455_35442 359 7.49 Mlig455_037038

Neo: -

Age: -

 0.968 - - - - 0.968 - Mlig455_037038 {REF} {Length: 2728} {Pfam: Acyltransferase family [PF01757.24, score=100.8]; Nose resistant-to-fluoxetine protein, N-terminal domain [PF20146.1, score=67.3]} {Mouse: ENSMUSG00000046610, Oacyl, O-acyltransferase like, [Score=169, Expect=1e-43]} {Dmel: FBgn0052645, CG32645, [Score=259, Expect=3e-74]} {Celegans: WBGene00007833, oac-6, O-ACyltransferase homolog, [RH, Score=235, Expect=1e-66]} {RNA1509_19999} {RNA1310_7490.1, RNA1509_19999} {RNA1509_19999, RNA815_17892}
46. MligTC455_31890 210 4.38 Mlig455_070942

Neo: -

Age: logFC(26M/2M)=-0.564

 0.966 - - - - 0.966 - Mlig455_070942 {REF} {Length: 2335} {Pfam: MULE transposase domain [PF10551.11, score=21.4]; Domain of unknown function (DUF4806) [PF16064.7, score=19.0]} {Smed: dd_Smed_v6_24877_0_1, dd_Smed_v6_24877_0_1, [Score=52.0, Expect=2e-08]} {RNA1509_28268} {RNA1310_1293.1} {RNA815_1077}
47. MligTC455_19939 22 0.45 Mlig455_011563

Neo: -

Age: -

 0.965 - - - - 0.965 - Mlig455_011563 {REF} {Length: 867} {NoTransDecoderORF} {RNA1310_143071} {RNA815_42689}
48. MligTC455_33217 350 7.3 Mlig455_017510, Mlig455_025979, Mlig455_030680, Mlig455_060677, Mlig455_070125

Neo: -

Age: Down-Up-Down

 0.965 - - - - 0.965 -

Mlig455_017510 {REF} {Length: 518} {NoTransDecoderORF} {RNA1509_35799} {RNA1310_37183} {RNA815_7155}

Mlig455_025979 {REF} {Length: 1819} {NoTransDecoderORF} {RNA1509_44389} {RNA1310_14765.1} {RNA815_7155}

Mlig455_030680 {REF} {Length: 1230} {NoTransDecoderORF} {RNA1509_44389} {RNA1310_14765.2} {RNA815_7155}

Mlig455_060677 {REF} {Length: 6928} {NoTransDecoderORF} {RNA1509_33795, RNA1509_44389} {RNA1310_14765.2, RNA1509_33795} {RNA1509_33795, RNA815_7155}

Mlig455_070125 {REF} {Length: 5305} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_44389} {RNA1310_14765.2} {RNA815_7155}
49. MligTC455_04756 68 1.42 Mlig455_017448

Neo: -

Age: -

 KCNAB2 0.964 - - - - 0.964 - Mlig455_017448 {REF} {Length: 3353} {Pfam: Aldo/keto reductase family [PF00248.23, score=176.1]} {Human: ENSG00000069424, KCNAB2, potassium voltage-gated channel subfamily A regulatory beta subunit 2, [Score=411, Expect=7e-141]; ENSG00000169282, KCNAB1, potassium voltage-gated channel subfamily A member regulatory beta subunit 1, [Score=411, Expect=2e-140]; ENSG00000170049, KCNAB3, potassium voltage-gated channel subfamily A regulatory beta subunit 3, [Score=392, Expect=5e-133]} {Mouse: ENSMUSG00000028931, Kcnab2, potassium voltage-gated channel, shaker-related subfamily, beta member 2, [Score=413, Expect=9e-142]; ENSMUSG00000027827, Kcnab1, potassium voltage-gated channel, shaker-related subfamily, beta member 1, [Score=411, Expect=1e-140]} {Dmel: FBgn0263220, Hk, Hyperkinetic, [Score=266, Expect=3e-84]} {Celegans: WBGene00015565, C07D8.6, [Score=57.0, Expect=1e-08]} {RNA1509_11669} {RNA1310_37865} {RNA815_27885}
50. MligTC455_39378 137 2.86 Mlig455_051216

Neo: -

Age: logFC(26M/2M)=0.949

 DLGAP4 0.962 - - - - 0.962 - Mlig455_051216 {REF} {Length: 5466} {Pfam: Guanylate-kinase-associated protein (GKAP) protein [PF03359.15, score=63.3]} {Human: ENSG00000080845, DLGAP4, DLG associated protein 4, [RH, Score=65.9, Expect=3e-10]} {Mouse: ENSMUSG00000061689, Dlgap4, DLG associated protein 4, [RH, Score=65.5, Expect=2e-10]} {Dmel: FBgn0259978, vlc, vulcan, [RH, Score=69.3, Expect=8e-12]} {Smed: dd_Smed_v6_5253_0_1, dd_Smed_v6_5253_0_1, [RH, Score=99.8, Expect=2e-21]} {RNA1509_36210} {RNA1310_5783.1} {RNA815_33881}
51. MligTC455_42820 154 3.21 Mlig455_029557

Neo: -

Age: -

 LARGE1 0.962 - - - - 0.962 - Mlig455_029557 {REF} {Length: 1795} {Pfam: Glycosyl-transferase for dystroglycan [PF13896.8, score=135.5]} {Human: ENSG00000133424, LARGE1, LARGE xylosyl- and glucuronyltransferase 1, [Score=262, Expect=4e-82]} {Mouse: ENSMUSG00000004383, Large1, LARGE xylosyl- and glucuronyltransferase 1, [Score=262, Expect=8e-82]; ENSMUSG00000040434, Large2, LARGE xylosyl- and glucuronyltransferase 2, [Score=258, Expect=4e-81]} {Dmel: FBgn0032457, CG15483, [Score=62.8, Expect=7e-11]} {Celegans: WBGene00010716, lge-1, Glycosyltransferase-like protein LARGE, [Score=127, Expect=5e-33]} {Smed: dd_Smed_v6_15269_0_1, dd_Smed_v6_15269_0_1, [Score=290, Expect=2e-95]} {RNA1509_47482} {RNA1310_56850.2} {RNA815_37190}
52. MligTC455_08638 310 6.46 Mlig455_062686

Neo: -

Age: Up-Down-Down

 CTNND2 0.961 - - - - 0.961 - Mlig455_062686 {REF} {Length: 6196} {TRANSSPLICED} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=111.2]; HEAT repeats [PF13646.8, score=23.1]} {Human: ENSG00000169862, CTNND2, catenin delta 2, [RH, Score=358, Expect=1e-105]; ENSG00000144283, PKP4, plakophilin 4, [RH, Score=341, Expect=3e-99]} {Mouse: ENSMUSG00000022240, Ctnnd2, catenin (cadherin associated protein), delta 2, [RH, Score=353, Expect=1e-103]; ENSMUSG00000026991, Pkp4, plakophilin 4, [RH, Score=341, Expect=1e-99]} {Dmel: FBgn0260799, p120ctn, Adherens junction protein p120, [RH, Score=397, Expect=7e-124]} {Celegans: WBGene00002175, jac-1, Juxtamembrane domain-associated catenin, [RH, Score=303, Expect=4e-86]} {Smed: dd_Smed_v6_6256_0_1, dd_Smed_v6_6256_0_1, [RH, Score=241, Expect=5e-67]} {RNA1509_13591} {RNA1310_6045} {RNA815_14763}
53. MligTC455_51834 708 14.75 Mlig455_020885

Neo: -

Age: logFC(26M/2M)=-0.486

 0.961 - - - - - 0.961 Mlig455_020885 {REF} {Length: 3911} {RNA1509_11544} {RNA1310_10250.1} {RNA815_17170}
54. MligTC455_32487 595 12.39 Mlig455_017119

Neo: -

Age: logFC(26M/2M)=-0.391

 0.959 - - - - 0.959 - Mlig455_017119 {REF} {Length: 2322} {RNA1509_10657} {RNA1310_11689, RNA1509_10657} {RNA1509_10657, RNA815_5499}
55. MligTC455_33995 174 3.63 Mlig455_042151

Neo: -

Age: logFC(26M/2M)=-0.705

 ANK1 0.959 - - - - 0.959 - Mlig455_042151 {REF} {Length: 8174} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=414.4]; Ankyrin repeats (many copies) [PF13637.8, score=253.9]; Ankyrin repeats (many copies) [PF13857.8, score=156.9]; Ankyrin repeat [PF13606.8, score=149.6]; Ankyrin repeat [PF00023.32, score=87.1]; Family of unknown function (DUF6189) [PF19688.1, score=71.1]; 3,4-dihydroxy-2-butanone 4-phosphate synthase [PF00926.21, score=44.8]; Domain of unknown function (DUF6487) [PF20097.1, score=28.5]} {Human: ENSG00000029534, ANK1, ankyrin 1, [Score=81.6, Expect=1e-14]} {Mouse: ENSMUSG00000031543, Ank1, ankyrin 1, erythroid, [Score=71.6, Expect=9e-12]; ENSMUSG00000014498, Ankrd52, ankyrin repeat domain 52, [Score=68.2, Expect=9e-11]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=65.5, Expect=4e-10]} {RNA1509_28890} {RNA1310_16696.1, RNA1509_28890} {RNA1509_28890, RNA815_12859.1}
56. MligTC455_42821 155 3.22 Mlig455_040440

Neo: -

Age: -

 LARGE1 0.959 - - - - 0.959 - Mlig455_040440 {REF} {Length: 5152} {TRANSSPLICED} {Pfam: Glycosyl-transferase for dystroglycan [PF13896.8, score=181.1]; Glycosyl transferase family 8 [PF01501.22, score=52.6]} {Human: ENSG00000133424, LARGE1, LARGE xylosyl- and glucuronyltransferase 1, [RH, Score=649, Expect=0.0]; ENSG00000165905, LARGE2, LARGE xylosyl- and glucuronyltransferase 2, [RH, Score=620, Expect=0.0]} {Mouse: ENSMUSG00000004383, Large1, LARGE xylosyl- and glucuronyltransferase 1, [RH, Score=646, Expect=0.0]; ENSMUSG00000040434, Large2, LARGE xylosyl- and glucuronyltransferase 2, [RH, Score=622, Expect=0.0]} {Dmel: FBgn0032457, CG15483, [RH, Score=67.8, Expect=1e-11]} {Celegans: WBGene00010716, lge-1, Glycosyltransferase-like protein LARGE, [RH, Score=304, Expect=1e-93]} {Smed: dd_Smed_v6_15269_0_1, dd_Smed_v6_15269_0_1, [RH, Score=484, Expect=6e-165]} {RNA1509_51185} {RNA1310_11436, RNA1509_51185} {RNA1509_51185, RNA815_10031}
57. MligTC455_05144 33 0.69 Mlig455_036438

Neo: -

Age: -

 0.958 - - - - 0.958 - Mlig455_036438 {REF} {Length: 891} {NoTransDecoderORF} {RNA1310_36060}
58. MligTC455_38205 600 12.5 Mlig455_057698

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.274

 0.958 - - - - 0.958 - Mlig455_057698 {REF} {Length: 1671} {Pfam: Protein of unknown function with motif GDWWSH [PF15667.7, score=76.0]} {Smed: dd_Smed_v6_6622_0_1, dd_Smed_v6_6622_0_1, [RH, Score=116, Expect=1e-30]} {RNA1509_16386} {RNA1310_17948.1} {RNA815_6839.1}
59. MligTC455_46851 507 10.56 Mlig455_059440

Neo: -

Age: logFC(26M/2M)=-0.309

 0.958 - - - - 0.958 - Mlig455_059440 {REF} {Length: 3521} {TRANSSPLICED} {Pfam: Coiled-coil domain-containing protein 158 [PF15921.7, score=48.5]} {Mouse: ENSMUSG00000050050, Ccdc158, coiled-coil domain containing 158, [RH, Score=85.5, Expect=2e-16]} {Smed: dd_Smed_v6_10831_0_1, dd_Smed_v6_10831_0_1, [RH, Score=72.8, Expect=7e-13]} {RNA1509_28804, RNA1509_7522} {RNA1310_3662, RNA1509_28804} {RNA1509_28804, RNA815_5689}
60. MligTC455_42189 996 20.75 Mlig455_049567

Neo: -

Age: -

 ATP1B1 0.956 - - - - 0.956 - Mlig455_049567 {REF} {Length: 2719} {TRANSSPLICED} {Pfam: Sodium / potassium ATPase beta chain [PF00287.20, score=206.6]} {Human: ENSG00000143153, ATP1B1, ATPase Na+/K+ transporting subunit beta 1, [RH, Score=129, Expect=1e-34]} {Mouse: ENSMUSG00000026576, Atp1b1, ATPase, Na+/K+ transporting, beta 1 polypeptide, [RH, Score=130, Expect=2e-35]} {Dmel: FBgn0032946, nrv3, nervana 3, [RH, Score=162, Expect=2e-47]} {Celegans: WBGene00007646, nkb-1, Sodium/potassium-transporting ATPase subunit beta-1, [Score=156, Expect=2e-45]} {Smed: dd_Smed_v6_7917_0_1, dd_Smed_v6_7917_0_1, [Score=228, Expect=1e-73]} {RNA1509_10587, RNA1509_45937} {RNA1310_12857.1, RNA1509_10587, RNA1509_45937} {RNA1509_10587, RNA1509_45937, RNA815_10364}
61. MligTC455_12056 104 2.16 Mlig455_062444

Neo: -

Age: Down-Up-Down

 IGFALS 0.954 - - - - 0.954 - Mlig455_062444 {REF} {Length: 4624} {Pfam: Leucine rich repeat [PF13855.8, score=119.1]; Leucine Rich repeats (2 copies) [PF12799.9, score=66.1]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=56.3]; Leucine-rich repeat [PF14580.8, score=29.8]; Leucine Rich Repeat [PF00560.35, score=22.9]} {Human: ENSG00000099769, IGFALS, insulin like growth factor binding protein acid labile subunit, [Score=82.8, Expect=2e-15]; ENSG00000255690, TRIL, TLR4 interactor with leucine rich repeats, [Score=82.4, Expect=2e-15]; ENSG00000139263, LRIG3, leucine rich repeats and immunoglobulin like domains 3, [Score=80.9, Expect=8e-15]} {Mouse: ENSMUSG00000051379, Flrt3, fibronectin leucine rich transmembrane protein 3, [RH, Score=83.2, Expect=7e-16]} {Dmel: FBgn0259677, CG42346, [Score=78.2, Expect=4e-14]} {Celegans: WBGene00020649, sma-10, Leucine-rich repeats and immunoglobulin-like domains protein sma-10, [Score=77.8, Expect=2e-14]} {Smed: dd_Smed_v6_13247_0_1, dd_Smed_v6_13247_0_1, [RH, Score=105, Expect=7e-23]} {RNA1509_11667} {RNA1310_3242, RNA1509_11667} {RNA1509_11667, RNA815_522}
62. MligTC455_31001 1473 30.69 Mlig455_024877, Mlig455_068443

Neo: -

Age: -

Region-enriched R8: 2.076/0.01787

 MPEG1 0.954 - - - - 0.954 -

Mlig455_024877 {REF} {Length: 3371} {Pfam: MAC/Perforin domain [PF01823.21, score=139.0]} {Human: ENSG00000197629, MPEG1, macrophage expressed 1, [RH, Score=362, Expect=4e-108]} {Mouse: ENSMUSG00000046805, Mpeg1, macrophage expressed gene 1, [RH, Score=368, Expect=2e-110]} {Smed: dd_Smed_v6_983_0_1, dd_Smed_v6_983_0_1, [RH, Score=355, Expect=1e-106]} {RNA1509_21688, RNA1509_30083, RNA1509_44998, RNA1509_4699} {RNA1310_4591, RNA1509_21688, RNA1509_30083, RNA1509_44998} {RNA1509_21688, RNA1509_30083, RNA1509_44998, RNA815_1433.1}

Mlig455_068443 {REF} {Length: 5971} {Pfam: MAC/Perforin domain [PF01823.21, score=139.0]} {Human: ENSG00000197629, MPEG1, macrophage expressed 1, [RH, Score=362, Expect=4e-108]} {Mouse: ENSMUSG00000046805, Mpeg1, macrophage expressed gene 1, [RH, Score=368, Expect=2e-110]} {Smed: dd_Smed_v6_983_0_1, dd_Smed_v6_983_0_1, [RH, Score=355, Expect=1e-106]} {RNA1509_4699} {RNA1310_4591} {RNA815_1433.1}
63. MligTC455_20869 354 7.38 Mlig455_048463

Neo: -

Age: -

 SARAF 0.952 - - - - - 0.952 Mlig455_048463 {REF} {Length: 3486} {Pfam: SOCE-associated regulatory factor of calcium homoeostasis [PF06682.14, score=201.6]} {Human: ENSG00000133872, SARAF, store-operated calcium entry associated regulatory factor, [Score=136, Expect=2e-37]} {Mouse: ENSMUSG00000031532, Saraf, store-operated calcium entry-associated regulatory factor, [Score=126, Expect=1e-33]} {Celegans: WBGene00011529, T06D8.9, [Score=122, Expect=1e-32]} {Smed: dd_Smed_v6_809_0_1, dd_Smed_v6_809_0_1, [Score=154, Expect=2e-45]} {RNA1509_37606} {RNA1310_29107} {RNA815_13291}
64. MligTC455_23002 1386 28.88 Mlig455_066079, Mlig455_066121

Neo: -

Age: Down-Down-Up

 ANKRD50 0.952 - - - - 0.952 -

Mlig455_066079 {REF} {Length: 4539} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=152.7]; Ankyrin repeats (many copies) [PF13637.8, score=140.9]; Ankyrin repeat [PF13606.8, score=112.2]; Ankyrin repeat [PF00023.32, score=105.1]; Ankyrin repeats (many copies) [PF13857.8, score=100.0]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=134, Expect=8e-34]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=131, Expect=4e-33]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=114, Expect=3e-27]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=108, Expect=1e-25]} {Smed: dd_Smed_v6_6779_0_1, dd_Smed_v6_6779_0_1, [Score=117, Expect=1e-28]} {RNA1509_33878, RNA1509_47884, RNA1509_50045, RNA1509_5303} {RNA1310_6276, RNA1509_33878, RNA1509_47884, RNA1509_50045} {RNA1509_33878, RNA1509_47884, RNA1509_50045, RNA815_1153}

Mlig455_066121 {REF} {Length: 4098} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=236.7]; Ankyrin repeats (many copies) [PF13637.8, score=202.9]; Protein kinase domain [PF00069.27, score=191.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=162.2]; Ankyrin repeat [PF13606.8, score=159.1]; Ankyrin repeat [PF00023.32, score=144.3]; Ankyrin repeats (many copies) [PF13857.8, score=135.5]; ABC1 atypical kinase-like domain [PF03109.18, score=32.5]; Fungal protein kinase [PF17667.3, score=31.9]; Kinase-like [PF14531.8, score=28.5]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=203, Expect=4e-53]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=201, Expect=1e-52]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=158, Expect=3e-39]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=157, Expect=5e-39]} {Smed: dd_Smed_v6_11663_0_4, dd_Smed_v6_11663_0_4, [Score=198, Expect=2e-53]} {RNA1509_5303} {RNA1310_6276} {RNA815_1153}
65. MligTC455_34585 460 9.58 Mlig455_055017

Neo: -

Age: logFC(26M/2M)=-0.577

 SMTN 0.951 - - - - 0.951 - Mlig455_055017 {REF} {Length: 6974} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=176.3]; Immunoglobulin domain [PF13927.8, score=114.3]; Calponin homology (CH) domain [PF00307.33, score=68.2]; Immunoglobulin V-set domain [PF07686.19, score=51.1]; Smoothelin cytoskeleton protein [PF12510.10, score=44.4]; Immunoglobulin domain [PF00047.27, score=43.3]; Immunoglobulin domain [PF13895.8, score=30.4]; CAMSAP CH domain [PF11971.10, score=29.0]; Natural killer cell receptor 2B4 [PF11465.10, score=21.4]; Izumo-like Immunoglobulin domain [PF16706.7, score=21.4]} {Human: ENSG00000183963, SMTN, smoothelin, [RH, Score=164, Expect=4e-40]} {Mouse: ENSMUSG00000020439, Smtn, smoothelin, [Score=155, Expect=1e-37]} {Dmel: FBgn0085446, CG34417, [RH, Score=168, Expect=4e-41]} {Celegans: WBGene00020530, T15B12.1, [Score=138, Expect=3e-34]} {Smed: dd_Smed_v6_6934_0_1, dd_Smed_v6_6934_0_1, [Score=156, Expect=4e-40]} {RNA1509_18420, RNA1509_3882} {RNA1310_786, RNA1509_18420, RNA1509_3882} {RNA1509_18420, RNA1509_3882, RNA815_238.1}
66. MligTC455_35878 750 15.63 Mlig455_034777

Neo: -

Age: -

 DSCAML1 0.951 - - - - 0.951 - Mlig455_034777 {REF} {Length: 7967} {Pfam: Immunoglobulin domain [PF13927.8, score=115.3]; Fibronectin type III domain [PF00041.23, score=102.0]; Immunoglobulin I-set domain [PF07679.18, score=67.0]; Immunoglobulin domain [PF13895.8, score=56.3]; Immunoglobulin V-set domain [PF07686.19, score=43.7]; Immunoglobulin domain [PF00047.27, score=35.4]} {Human: ENSG00000177103, DSCAML1, DS cell adhesion molecule like 1, [Score=136, Expect=3e-31]} {Mouse: ENSMUSG00000032087, Dscaml1, DS cell adhesion molecule like 1, [Score=136, Expect=3e-31]} {Dmel: FBgn0263219, Dscam4, Down syndrome cell adhesion molecule 4, [Score=116, Expect=2e-25]} {Celegans: WBGene00004371, rig-4, Protein sidekick homolog, [Score=84.7, Expect=9e-16]} {Smed: dd_Smed_v6_3024_0_1, dd_Smed_v6_3024_0_1, [Score=252, Expect=6e-67]} {RNA1509_14715, RNA1509_17640, RNA1509_44798} {RNA1310_789, RNA1509_14715, RNA1509_17640, RNA1509_44798} {RNA1509_14715, RNA1509_17640, RNA1509_44798, RNA815_11499}
67. MligTC455_38369 100 2.08 Mlig455_026465

Neo: -

Age: -

 SSUH2 0.951 - - - - 0.951 - Mlig455_026465 {REF} {Length: 1913} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [RH, Score=238, Expect=2e-74]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [RH, Score=200, Expect=2e-60]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=122, Expect=4e-31]} {RNA1509_6425} {RNA1310_32434} {RNA815_16161}
68. MligTC455_02159 20 0.41 Mlig455_025396

Neo: -

Age: -

 0.95 - - - - 0.950 - Mlig455_025396 {REF} {Length: 270} {NoTransDecoderORF} {RNA1509_41075} {RNA1310_114067} {RNA815_22193}
69. MligTC455_12141 899 18.73 Mlig455_042988

Neo: -

Age: -

 0.95 - - - - - 0.950 Mlig455_042988 {REF} {Length: 484} {NoTransDecoderORF} {RNA1509_30285} {RNA1310_54718} {RNA815_10487}
70. MligTC455_16167 177 3.69 Mlig455_065707

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.428

Region-enriched R2: 4.313/0.00011

 B3GALT5 0.95 - - - - 0.950 - Mlig455_065707 {REF} {Length: 4598} {Pfam: Galactosyltransferase [PF01762.23, score=160.3]} {Human: ENSG00000183778, B3GALT5, beta-1,3-galactosyltransferase 5, [RH, Score=130, Expect=2e-33]} {Mouse: ENSMUSG00000034780, B3galt1, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1, [Score=115, Expect=4e-28]; ENSMUSG00000074892, B3galt5, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5, [Score=111, Expect=9e-27]} {Dmel: FBgn0035558, CG11357, [RH, Score=148, Expect=4e-39]} {Celegans: WBGene00000270, bre-5, Beta-1,3-galactosyltransferase bre-5, [Score=67.0, Expect=5e-12]} {Smed: dd_Smed_v6_12783_0_1, dd_Smed_v6_12783_0_1, [Score=152, Expect=6e-42]} {RNA1509_45540} {RNA1310_2435} {RNA815_25407}
71. MligTC455_17646 1198 24.96 Mlig455_048620, Mlig455_048699, Mlig455_048734

Neo: -

Age: logFC(26M/2M)=0.248

Region-enriched R2: 1.637/0.02593
Region-enriched R5: 1.108/0.02454

 WDR86 0.95 - - - - 0.950 -

Mlig455_048620 {REF} {Length: 3284} {Pfam: WD domain, G-beta repeat [PF00400.34, score=149.4]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=42.9]; PQQ-like domain [PF13570.8, score=25.8]; Nucleoporin Nup120/160 [PF11715.10, score=22.0]} {Human: ENSG00000187260, WDR86, WD repeat domain 86, [RH, Score=318, Expect=6e-105]} {Mouse: ENSMUSG00000055235, Wdr86, WD repeat domain 86, [RH, Score=313, Expect=2e-103]} {Dmel: FBgn0283468, slmb, supernumerary limbs, [Score=125, Expect=2e-30]} {Celegans: WBGene00004767, sel-10, F-box/WD repeat-containing protein sel-10, [Score=135, Expect=2e-34]} {Smed: dd_Smed_v6_19827_0_1, dd_Smed_v6_19827_0_1, [RH, Score=425, Expect=5e-147]} {RNA1509_20850} {RNA1310_16023.1, RNA1509_20850} {RNA1509_20850, RNA815_7261}

Mlig455_048699 {REF} {Length: 2794} {Pfam: WD domain, G-beta repeat [PF00400.34, score=149.1]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=42.7]; PQQ-like domain [PF13570.8, score=25.5]; Nucleoporin Nup120/160 [PF11715.10, score=22.0]} {Human: ENSG00000187260, WDR86, WD repeat domain 86, [RH, Score=318, Expect=6e-105]} {Mouse: ENSMUSG00000055235, Wdr86, WD repeat domain 86, [RH, Score=314, Expect=2e-103]} {Dmel: FBgn0283468, slmb, supernumerary limbs, [Score=124, Expect=2e-30]} {Celegans: WBGene00004767, sel-10, F-box/WD repeat-containing protein sel-10, [Score=136, Expect=2e-34]} {Smed: dd_Smed_v6_19827_0_1, dd_Smed_v6_19827_0_1, [RH, Score=423, Expect=4e-146]} {RNA1509_20850} {RNA1310_16023.2} {RNA815_7261}

Mlig455_048734 {REF} {Length: 3308} {Pfam: WD domain, G-beta repeat [PF00400.34, score=149.4]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=42.9]; PQQ-like domain [PF13570.8, score=25.8]; Nucleoporin Nup120/160 [PF11715.10, score=22.0]} {Human: ENSG00000187260, WDR86, WD repeat domain 86, [RH, Score=318, Expect=6e-105]} {Mouse: ENSMUSG00000055235, Wdr86, WD repeat domain 86, [RH, Score=313, Expect=2e-103]} {Dmel: FBgn0283468, slmb, supernumerary limbs, [Score=125, Expect=2e-30]} {Celegans: WBGene00004767, sel-10, F-box/WD repeat-containing protein sel-10, [Score=135, Expect=2e-34]} {Smed: dd_Smed_v6_19827_0_1, dd_Smed_v6_19827_0_1, [RH, Score=425, Expect=5e-147]} {RNA1509_20850} {RNA1310_16023.1} {RNA815_7261}
72. MligTC455_33131 549 11.45 Mlig455_022594, Mlig455_026005, Mlig455_070429

Neo: Germline

Age: logFC(26M/2M)=-0.432

 KY 0.95 - - - - 0.950 -

Mlig455_022594 {REF} {Length: 667} {Pfam: Helix-turn-helix domain of transposase family ISL3 [PF13542.8, score=27.8]} {RNA1509_53064} {RNA1310_18119} {RNA815_4493}

Mlig455_026005 {REF} {Length: 5002} {Pfam: Transglutaminase-like superfamily [PF01841.21, score=25.4]} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=94.7, Expect=2e-19]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=95.5, Expect=1e-19]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=105, Expect=1e-22]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=105, Expect=2e-23]} {Smed: dd_Smed_v6_5330_0_1, dd_Smed_v6_5330_0_1, [Score=111, Expect=1e-24]} {RNA1509_11170} {RNA1310_2597.1} {RNA815_17158}

Mlig455_070429 {REF} {Length: 5697} {Pfam: Transglutaminase-like superfamily [PF01841.21, score=25.4]} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=97.4, Expect=5e-20]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=96.7, Expect=6e-20]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=113, Expect=4e-25]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=113, Expect=3e-25]} {Smed: dd_Smed_v6_5330_0_1, dd_Smed_v6_5330_0_1, [Score=113, Expect=4e-25]} {RNA1509_11170, RNA1509_29877} {RNA1310_2597.1, RNA1509_11170, RNA1509_29877} {RNA1509_11170, RNA1509_29877, RNA815_3609}
73. MligTC455_50375 2086 43.45 Mlig455_016459, Mlig455_016525, Mlig455_049814

Neo: -

Age: -

 0.95 - - - - 0.950 -

Mlig455_016459 {REF} {Length: 2149} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=23.2]; Ankyrin repeats (many copies) [PF13637.8, score=20.7]} {Smed: dd_Smed_v6_17861_0_1, dd_Smed_v6_17861_0_1, [RH, Score=120, Expect=2e-30]} {RNA1509_10140} {RNA1310_11634.1} {RNA815_4167}

Mlig455_016525 {REF} {Length: 2207} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=23.2]; Ankyrin repeats (many copies) [PF13637.8, score=20.7]} {Smed: dd_Smed_v6_17861_0_1, dd_Smed_v6_17861_0_1, [RH, Score=120, Expect=2e-30]} {RNA1509_10140, RNA1509_60156} {RNA1310_11634.1, RNA1509_10140, RNA1509_60156} {RNA1509_10140, RNA1509_60156, RNA815_4167}

Mlig455_049814 {REF} {Length: 2210} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=23.2]; Ankyrin repeats (many copies) [PF13637.8, score=20.7]} {Smed: dd_Smed_v6_17861_0_1, dd_Smed_v6_17861_0_1, [RH, Score=120, Expect=2e-30]} {RNA1509_10140} {RNA1310_11634.1} {RNA815_4167}
74. MligTC455_51953 781 16.26 Mlig455_038445

Neo: -

Age: Down-Up-Up

 0.95 - - - - 0.950 - Mlig455_038445 {REF} {Length: 1860} {Pfam: Wnt and FGF inhibitory regulator [PF13908.8, score=19.3]} {RNA1509_20653} {RNA1310_15381} {RNA815_5778}

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