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Results for MligTC455_54177

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_54177 858 17.88 Mlig455_020727

Neo: -

Age: Down-Down-Up

Region-enriched R8: 2.370/0.00010
Region-enriched R7: 2.006/0.00008

Mlig455_020727 {REF} {Length: 2702} {Smed: dd_Smed_v6_5057_0_1, dd_Smed_v6_5057_0_1, [RH, Score=91.7, Expect=4e-20]} {RNA1509_10580} {RNA1310_9366} {RNA815_2566}

Cumulative graph for MligTC455_54177

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.193 4.255 0.36498 1.00000
RegionR2 0.257 4.255 0.57328 0.93180
RegionR3 -1.111 4.255 0.02065 0.24147
RegionR4 -1.296 4.255 0.01573 0.08545
RegionR5 -1.609 4.255 0.00146 0.01377
RegionR6 0.578 4.255 0.13342 0.65696
RegionR7 2.006 4.255 0.00000 0.00008
RegionR8 2.37 4.255 0.00000 0.00010

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -6.596 4.255 0.17673 0.91886
RegenerationR2 0.593 4.255 0.12430 0.54606
RegenerationR3 0.612 4.255 0.20515 0.64035
RegenerationR4 0.469 4.255 0.32014 0.75847
RegenerationR5 0.637 4.255 0.17675 0.60652
RegenerationR6 -0.504 4.255 0.24774 0.59607
RegenerationBL -1.494 4.255 0.00123 0.02611
RegenerationTP -0.752 4.255 0.08424 0.45982


Genes with expression patterns similar to MligTC455_54177

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_54177 858 17.88 Mlig455_020727

Neo: -

Age: Down-Down-Up

Region-enriched R8: 2.370/0.00010
Region-enriched R7: 2.006/0.00008

6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_020727 {REF} {Length: 2702} {Smed: dd_Smed_v6_5057_0_1, dd_Smed_v6_5057_0_1, [RH, Score=91.7, Expect=4e-20]} {RNA1509_10580} {RNA1310_9366} {RNA815_2566}
2. MligTC455_42170 342 7.12 Mlig455_038315

Neo: -

Age: Down-Up-Up

3.407 0.889 - - 0.751 0.953 0.814 Mlig455_038315 {REF} {Length: 2851} {Pfam: Innexin [PF00876.20, score=296.2]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=95.5, Expect=5e-21]} {Celegans: WBGene00006749, unc-9, Innexin unc-9, [Score=208, Expect=6e-62]} {Smed: dd_Smed_v6_10766_0_1, dd_Smed_v6_10766_0_1, [Score=276, Expect=2e-87]} {RNA1509_10527, RNA1509_45409} {RNA1310_14408, RNA1509_10527, RNA1509_45409} {RNA1509_10527, RNA1509_45409, RNA815_844.2}
3. MligTC455_25395 2547 53.06 Mlig455_012103, Mlig455_029022

Neo: -

Age: -

SLC46A3 2.625 - - - 0.886 0.950 0.789

Mlig455_012103 {REF} {Length: 2488} {Pfam: Major Facilitator Superfamily [PF07690.18, score=64.5]} {Human: ENSG00000139508, SLC46A3, solute carrier family 46 member 3, [Score=139, Expect=2e-35]; ENSG00000076351, SLC46A1, solute carrier family 46 member 1, [Score=135, Expect=4e-34]} {Mouse: ENSMUSG00000020829, Slc46a1, solute carrier family 46, member 1, [Score=146, Expect=5e-38]} {Celegans: WBGene00021159, Y4C6B.5, [Score=50.1, Expect=3e-06]} {Smed: dd_Smed_v6_5528_0_1, dd_Smed_v6_5528_0_1, [Score=179, Expect=2e-50]} {RNA1509_18925, RNA1509_45956} {RNA1310_14130.1, RNA1509_18925, RNA1509_45956} {RNA1509_18925, RNA1509_45956, RNA815_4522}

Mlig455_029022 {REF} {Length: 2776} {Pfam: Major Facilitator Superfamily [PF07690.18, score=64.1]} {Human: ENSG00000139508, SLC46A3, solute carrier family 46 member 3, [Score=142, Expect=2e-36]; ENSG00000076351, SLC46A1, solute carrier family 46 member 1, [Score=135, Expect=4e-34]} {Mouse: ENSMUSG00000020829, Slc46a1, solute carrier family 46, member 1, [Score=146, Expect=4e-38]} {Celegans: WBGene00021159, Y4C6B.5, [Score=50.1, Expect=3e-06]} {Smed: dd_Smed_v6_5528_0_1, dd_Smed_v6_5528_0_1, [Score=179, Expect=3e-50]} {RNA1509_18925} {RNA1310_14130.2} {RNA815_4522}
4. MligTC455_53778 951 19.82 Mlig455_007965, Mlig455_015595

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.392

Region-enriched R4: 2.645/0.00192

PRXL2C 1.852 - - - 0.902 0.950 -

Mlig455_007965 {REF} {Length: 1357} {Pfam: AhpC/TSA antioxidant enzyme [PF13911.8, score=24.2]} {Smed: dd_Smed_v6_4424_0_1, dd_Smed_v6_4424_0_1, [Score=108, Expect=6e-30]} {RNA1509_57652} {RNA1310_27001.1} {RNA815_11622}

Mlig455_015595 {REF} {Length: 1838} {Pfam: AhpC/TSA antioxidant enzyme [PF13911.8, score=40.9]} {Human: ENSG00000158122, PRXL2C, peroxiredoxin like 2C, [RH, Score=135, Expect=5e-39]} {Mouse: ENSMUSG00000021482, Aaed1, AhpC/TSA antioxidant enzyme domain containing 1, [Score=125, Expect=3e-35]} {Smed: dd_Smed_v6_4424_0_1, dd_Smed_v6_4424_0_1, [RH, Score=149, Expect=3e-45]} {RNA1509_57652} {RNA1310_27001.2, RNA1509_57652} {RNA1509_57652, RNA815_11622}
5. MligTC455_52239 629 13.1 Mlig455_029233

Neo: -

Age: logFC(26M/2M)=-0.429

ABCG2 1.848 - - - 0.889 0.959 - Mlig455_029233 {REF} {Length: 3918} {Pfam: ABC-2 type transporter [PF01061.26, score=125.2]; ABC transporter [PF00005.29, score=73.3]; ABC-2 type transporter [PF19055.2, score=43.6]; AAA domain, putative AbiEii toxin, Type IV TA system [PF13304.8, score=31.5]; RecF/RecN/SMC N terminal domain [PF02463.21, score=23.9]; AAA domain [PF13476.8, score=20.9]} {Human: ENSG00000118777, ABCG2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=541, Expect=0.0]} {Mouse: ENSMUSG00000029802, Abcg2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=546, Expect=0.0]} {Dmel: FBgn0003996, w, white, [Score=257, Expect=4e-74]} {Celegans: WBGene00012925, wht-8, WHiTe (Drosophila) related ABC transporter, [RH, Score=259, Expect=1e-75]} {Smed: dd_Smed_v6_4225_0_2, dd_Smed_v6_4225_0_2, [RH, Score=689, Expect=0.0]} {RNA1509_2851} {RNA1310_949.2} {RNA815_1895}
6. MligTC455_39145 860 17.92 Mlig455_045710

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.035/0.04635

1.845 - - - 0.889 0.956 - Mlig455_045710 {REF} {Length: 2657} {Pfam: Family of unknown function (DUF5580) [PF17743.3, score=80.4]} {Smed: dd_Smed_v6_9326_0_1, dd_Smed_v6_9326_0_1, [RH, Score=180, Expect=1e-49]} {RNA1509_11160, RNA1509_32698} {RNA1310_8387, RNA1509_11160, RNA1509_32698} {RNA1509_11160, RNA1509_32698, RNA815_15696.1}
7. MligTC455_39608 6604 137.59 Mlig455_023921, Mlig455_046482

Neo: -

Age: -

APP 1.844 - - - - 0.980 0.864

Mlig455_023921 {REF} {Length: 3702} {TRANSSPLICED} {Pfam: Amyloid A4 N-terminal heparin-binding [PF02177.18, score=48.7]; E2 domain of amyloid precursor protein [PF12925.9, score=43.8]; Beta-amyloid precursor protein C-terminus [PF10515.11, score=40.8]; Copper-binding of amyloid precursor, CuBD [PF12924.9, score=39.1]} {Human: ENSG00000142192, APP, amyloid beta precursor protein, [Score=84.3, Expect=3e-16]} {Mouse: ENSMUSG00000022892, App, amyloid beta (A4) precursor protein, [Score=84.0, Expect=3e-16]} {Dmel: FBgn0000108, Appl, beta amyloid protein precursor-like, [Score=85.9, Expect=6e-17]} {Celegans: WBGene00000149, apl-1, Beta-amyloid-like protein, [RH, Score=101, Expect=4e-22]} {Smed: dd_Smed_v6_2561_0_1, dd_Smed_v6_2561_0_1, [RH, Score=134, Expect=7e-33]} {RNA1509_11651, RNA1509_19546, RNA1509_2244, RNA1509_31480, RNA1509_4900} {RNA1310_3149.1, RNA1509_11651, RNA1509_19546, RNA1509_2244, RNA1509_31480, RNA1509_4900} {RNA1509_11651, RNA1509_19546, RNA1509_2244, RNA1509_31480, RNA1509_4900, RNA815_958.1}

Mlig455_046482 {REF} {Length: 3710} {TRANSSPLICED} {Pfam: Amyloid A4 N-terminal heparin-binding [PF02177.18, score=47.8]; E2 domain of amyloid precursor protein [PF12925.9, score=43.1]; Beta-amyloid precursor protein C-terminus [PF10515.11, score=40.8]; Copper-binding of amyloid precursor, CuBD [PF12924.9, score=39.2]} {Human: ENSG00000142192, APP, amyloid beta precursor protein, [Score=84.7, Expect=2e-16]} {Mouse: ENSMUSG00000022892, App, amyloid beta (A4) precursor protein, [Score=84.3, Expect=2e-16]} {Dmel: FBgn0000108, Appl, beta amyloid protein precursor-like, [Score=85.5, Expect=9e-17]} {Celegans: WBGene00000149, apl-1, Beta-amyloid-like protein, [RH, Score=103, Expect=9e-23]} {Smed: dd_Smed_v6_2561_0_1, dd_Smed_v6_2561_0_1, [RH, Score=138, Expect=3e-34]} {RNA1509_11651, RNA1509_35488} {RNA1310_3149.1, RNA1509_35488} {RNA1509_35488, RNA815_958.1}
8. MligTC455_41863 2653 55.27 Mlig455_003492, Mlig455_015564

Neo: -

Age: logFC(26M/2M)=-0.199

ERICH2 1.84 - - - 0.960 0.880 -

Mlig455_003492 {REF} {Length: 1511} {TRANSSPLICED} {Pfam: Fis1 C-terminal tetratricopeptide repeat [PF14853.8, score=19.5]} {Human: ENSG00000204334, ERICH2, glutamate rich 2, [RH, Score=60.1, Expect=4e-11]} {Mouse: ENSMUSG00000075302, Erich2, glutamate rich 2, [RH, Score=55.5, Expect=8e-09]} {RNA1509_23697, RNA1509_5420} {RNA1310_19735, RNA1509_23697, RNA1509_5420} {RNA1509_23697, RNA1509_5420, RNA815_20782}

Mlig455_015564 {REF} {Length: 1509} {TRANSSPLICED} {Pfam: Fis1 C-terminal tetratricopeptide repeat [PF14853.8, score=19.5]} {Human: ENSG00000204334, ERICH2, glutamate rich 2, [RH, Score=62.0, Expect=1e-11]} {Mouse: ENSMUSG00000075302, Erich2, glutamate rich 2, [RH, Score=55.8, Expect=6e-09]} {RNA1509_5420} {RNA1310_19735} {RNA815_20782}
9. MligTC455_43683 520 10.83 Mlig455_029440

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.407

1.835 - - - 0.881 0.954 - Mlig455_029440 {REF} {Length: 1842} {RNA1509_21217} {RNA1310_16933.1, RNA1509_21217} {RNA1509_21217, RNA815_7959}
10. MligTC455_39612 861 17.93 Mlig455_019206

Neo: -

Age: logFC(26M/2M)=-0.343

DLEC1 1.755 - - - 0.786 0.969 - Mlig455_019206 {REF} {Length: 7152} {TRANSSPLICED} {Pfam: Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin [PF15780.7, score=68.8]; Flagellar-associated PapD-like [PF14874.8, score=25.0]} {Human: ENSG00000008226, DLEC1, DLEC1, cilia and flagella associated protein, [RH, Score=721, Expect=0.0]} {Mouse: ENSMUSG00000038060, Dlec1, deleted in lung and esophageal cancer 1, [RH, Score=725, Expect=0.0]} {Smed: dd_Smed_v6_10833_0_1, dd_Smed_v6_10833_0_1, [RH, Score=813, Expect=0.0]} {RNA1509_3454} {RNA1310_859.1, RNA1509_3454} {RNA1509_3454, RNA815_262}
11. MligTC455_49179 1230 25.62 Mlig455_000575, Mlig455_030372

Neo: -

Age: Down-Up-Down

GRIK1 1.743 - - - 0.757 0.986 -

Mlig455_000575 {REF} {Length: 3002} {Pfam: Ligand-gated ion channel [PF00060.28, score=56.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=22.4]; Receptor family ligand binding region [PF01094.30, score=21.2]} {Human: ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=76.6, Expect=1e-13]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=73.6, Expect=1e-12]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=73.9, Expect=6e-13]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=73.2, Expect=1e-12]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=66.2, Expect=9e-11]} {Smed: dd_Smed_v6_10048_0_1, dd_Smed_v6_10048_0_1, [Score=71.2, Expect=1e-12]} {RNA1509_5131} {RNA1310_3885, RNA1509_5131} {RNA1509_5131, RNA815_1090.1}

Mlig455_030372 {REF} {Length: 3002} {Pfam: Ligand-gated ion channel [PF00060.28, score=56.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=22.5]; Receptor family ligand binding region [PF01094.30, score=21.4]} {Human: ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=76.6, Expect=1e-13]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=73.6, Expect=1e-12]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=73.9, Expect=6e-13]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=73.2, Expect=1e-12]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=65.5, Expect=1e-10]} {Smed: dd_Smed_v6_10048_0_1, dd_Smed_v6_10048_0_1, [Score=71.6, Expect=1e-12]} {RNA1509_5131} {RNA1310_3885} {RNA815_1090.1}
12. MligTC455_51902 1049 21.85 Mlig455_021705

Neo: -

Age: logFC(26M/2M)=-0.488

CHRNB3 1.742 - - - 0.784 0.958 - Mlig455_021705 {REF} {Length: 1861} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=147.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=72.7]} {Human: ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=191, Expect=2e-55]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=189, Expect=2e-54]; ENSG00000169684, CHRNA5, cholinergic receptor nicotinic alpha 5 subunit, [Score=182, Expect=6e-52]} {Mouse: ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=186, Expect=2e-53]; ENSMUSG00000035594, Chrna5, cholinergic receptor, nicotinic, alpha polypeptide 5, [Score=185, Expect=2e-53]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=182, Expect=4e-52]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [Score=177, Expect=2e-49]} {Celegans: WBGene00006774, unc-38, Acetylcholine receptor subunit alpha-type unc-38, [Score=174, Expect=7e-49]} {Smed: dd_Smed_v6_2019_0_1, dd_Smed_v6_2019_0_1, [Score=347, Expect=6e-116]} {RNA1509_8724} {RNA1310_17144.1} {RNA815_6285}
13. MligTC455_42171 910 18.96 Mlig455_050223

Neo: -

Age: -

Region-enriched R2: 1.714/0.04973

1.741 - - - 0.790 0.951 - Mlig455_050223 {REF} {Length: 2134} {Pfam: Innexin [PF00876.20, score=296.2]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=95.5, Expect=5e-21]} {Celegans: WBGene00006749, unc-9, Innexin unc-9, [Score=208, Expect=6e-62]} {Smed: dd_Smed_v6_10766_0_1, dd_Smed_v6_10766_0_1, [Score=276, Expect=2e-87]} {RNA1509_10527} {RNA1310_14408} {RNA815_844.2}
14. MligTC455_51903 1283 26.73 Mlig455_021657, Mlig455_067458

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.872

CHRNB1, CHRNB3 1.732 - - - 0.775 0.957 -

Mlig455_021657 {REF} {Length: 2044} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=147.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=73.5]} {Human: ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=193, Expect=5e-56]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=189, Expect=1e-54]} {Mouse: ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=187, Expect=8e-54]; ENSMUSG00000035594, Chrna5, cholinergic receptor, nicotinic, alpha polypeptide 5, [Score=186, Expect=1e-53]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=179, Expect=5e-51]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [Score=176, Expect=3e-49]} {Celegans: WBGene00006774, unc-38, Acetylcholine receptor subunit alpha-type unc-38, [Score=174, Expect=9e-49]} {Smed: dd_Smed_v6_2019_0_1, dd_Smed_v6_2019_0_1, [Score=346, Expect=9e-116]} {RNA1509_8724} {RNA1310_17144.1, RNA1509_8724} {RNA1509_8724, RNA815_6285}

Mlig455_067458 {REF} {Length: 1512} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=43.5]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=18.7]} {Human: ENSG00000283946, CHRNB1, cholinergic receptor nicotinic beta 1 subunit, [Score=48.1, Expect=7e-06]; ENSG00000170175, CHRNB1, cholinergic receptor nicotinic beta 1 subunit, [Score=48.1, Expect=7e-06]; ENSG00000117971, CHRNB4, cholinergic receptor nicotinic beta 4 subunit, [Score=47.8, Expect=1e-05]} {Mouse: ENSMUSG00000029205, Chrna9, cholinergic receptor, nicotinic, alpha polypeptide 9, [Score=47.4, Expect=1e-05]} {Celegans: WBGene00000055, acr-16, Acetylcholine receptor subunit alpha-type acr-16, [Score=46.6, Expect=1e-05]} {Smed: dd_Smed_v6_2019_0_1, dd_Smed_v6_2019_0_1, [Score=96.7, Expect=1e-22]} {RNA1509_8724} {RNA1310_17144.1} {RNA815_6285}
15. MligTC455_51229 6185 128.85 Mlig455_007849, Mlig455_007861

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.858

1.726 - - - 0.958 0.768 -

Mlig455_007849 {REF} {Length: 1089} {RNA1509_43926} {RNA1310_39956.1} {RNA815_20485}

Mlig455_007861 {REF} {Length: 1076} {RNA1509_43926, RNA1509_8131} {RNA1310_39956.1, RNA1509_43926, RNA1509_8131} {RNA1509_43926, RNA1509_8131, RNA815_20485}
16. MligTC455_42189 996 20.75 Mlig455_049567

Neo: -

Age: -

ATP1B1 1.725 - 0.757 - - 0.968 - Mlig455_049567 {REF} {Length: 2719} {TRANSSPLICED} {Pfam: Sodium / potassium ATPase beta chain [PF00287.20, score=206.6]} {Human: ENSG00000143153, ATP1B1, ATPase Na+/K+ transporting subunit beta 1, [RH, Score=129, Expect=1e-34]} {Mouse: ENSMUSG00000026576, Atp1b1, ATPase, Na+/K+ transporting, beta 1 polypeptide, [RH, Score=130, Expect=2e-35]} {Dmel: FBgn0032946, nrv3, nervana 3, [RH, Score=162, Expect=2e-47]} {Celegans: WBGene00007646, nkb-1, Sodium/potassium-transporting ATPase subunit beta-1, [Score=156, Expect=2e-45]} {Smed: dd_Smed_v6_7917_0_1, dd_Smed_v6_7917_0_1, [Score=228, Expect=1e-73]} {RNA1509_10587, RNA1509_45937} {RNA1310_12857.1, RNA1509_10587, RNA1509_45937} {RNA1509_10587, RNA1509_45937, RNA815_10364}
17. MligTC455_43616 1798 37.45 Mlig455_024513

Neo: -

Age: logFC(26M/2M)=-0.338

Region-enriched R2: 1.066/0.02738

CFAP57 1.683 - - - 0.732 0.951 - Mlig455_024513 {REF} {Length: 5805} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=65.8]; Crescentin protein [PF19220.2, score=26.3]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=25.5]; Autophagy protein 16 (ATG16) [PF08614.13, score=24.0]; Coiled-coil region of CCDC155 or KASH [PF14662.8, score=20.0]} {Human: ENSG00000243710, CFAP57, cilia and flagella associated protein 57, [RH, Score=1363, Expect=0.0]} {Mouse: ENSMUSG00000028730, Cfap57, cilia and flagella associated protein 57, [RH, Score=1360, Expect=0.0]} {Dmel: FBgn0034745, CG4329, [RH, Score=496, Expect=5e-155]} {Celegans: WBGene00003047, lis-1, Lissencephaly-1 homolog, [Score=55.1, Expect=2e-07]} {Smed: dd_Smed_v6_3323_0_1, dd_Smed_v6_3323_0_1, [RH, Score=1620, Expect=0.0]} {RNA1509_14259, RNA1509_18569, RNA1509_42897, RNA1509_836} {RNA1310_1737, RNA1509_14259, RNA1509_18569, RNA1509_42897} {RNA1509_14259, RNA1509_18569, RNA1509_42897, RNA815_558}
18. MligTC455_21914 6688 139.34 Mlig455_041245, Mlig455_053092

Neo: -

Age: -

FLNB 0.971 - - - - 0.971 -

Mlig455_041245 {REF} {Length: 5323} {Pfam: Filamin/ABP280 repeat [PF00630.21, score=341.5]} {Human: ENSG00000136068, FLNB, filamin B, [Score=238, Expect=1e-62]; ENSG00000196924, FLNA, filamin A, [Score=230, Expect=3e-60]} {Mouse: ENSMUSG00000031328, Flna, filamin, alpha, [Score=243, Expect=1e-64]} {Dmel: FBgn0028371, jbug, jitterbug, [RH, Score=429, Expect=2e-124]} {Celegans: WBGene00016006, fln-2, FiLamiN (Actin binding protein) homolog, [RH, Score=469, Expect=3e-139]} {Smed: dd_Smed_v6_14262_0_1, dd_Smed_v6_14262_0_1, [RH, Score=265, Expect=2e-73]} {RNA1509_1061} {RNA1310_1557.1, RNA1509_1061} {RNA1509_1061, RNA815_236}

Mlig455_053092 {REF} {Length: 4805} {Pfam: Filamin/ABP280 repeat [PF00630.21, score=342.0]} {Human: ENSG00000136068, FLNB, filamin B, [Score=239, Expect=4e-63]; ENSG00000196924, FLNA, filamin A, [Score=231, Expect=2e-60]} {Mouse: ENSMUSG00000031328, Flna, filamin, alpha, [Score=244, Expect=9e-65]} {Dmel: FBgn0028371, jbug, jitterbug, [RH, Score=430, Expect=1e-124]} {Celegans: WBGene00016006, fln-2, FiLamiN (Actin binding protein) homolog, [RH, Score=471, Expect=8e-140]} {Smed: dd_Smed_v6_14262_0_1, dd_Smed_v6_14262_0_1, [RH, Score=267, Expect=2e-74]} {RNA1509_1061} {RNA1310_1557.1} {RNA815_236}
19. MligTC455_20230 1282 26.71 Mlig455_003493, Mlig455_015562

Neo: -

Age: logFC(26M/2M)=-0.236

FAM227A, FAM227B 0.969 - - - - 0.969 -

Mlig455_003493 {REF} {Length: 2231} {TRANSSPLICED} {Pfam: Protein of unknown function [PF14922.8, score=146.0]} {Human: ENSG00000184949, FAM227A, family with sequence similarity 227 member A, [Score=111, Expect=2e-25]} {Mouse: ENSMUSG00000042564, Fam227a, family with sequence similarity 227, member A, [RH, Score=96.7, Expect=8e-21]; ENSMUSG00000027209, Fam227b, family with sequence similarity 227, member B, [RH, Score=93.6, Expect=6e-20]} {Smed: dd_Smed_v6_15102_0_3, dd_Smed_v6_15102_0_3, [Score=157, Expect=3e-42]} {RNA1509_44428} {RNA1310_6983.2} {RNA815_5876}

Mlig455_015562 {REF} {Length: 2171} {TRANSSPLICED} {Pfam: Protein of unknown function [PF14922.8, score=146.7]} {Human: ENSG00000166262, FAM227B, family with sequence similarity 227 member B, [RH, Score=107, Expect=2e-24]} {Mouse: ENSMUSG00000027209, Fam227b, family with sequence similarity 227, member B, [RH, Score=98.6, Expect=1e-21]} {Smed: dd_Smed_v6_15102_0_7, dd_Smed_v6_15102_0_7, [Score=178, Expect=5e-50]} {RNA1509_58462} {RNA1310_11701} {RNA815_12354}
20. MligTC455_43528 1273 26.52 Mlig455_068411

Neo: -

Age: Down-Up-Up

0.967 - - - - 0.967 - Mlig455_068411 {REF} {Length: 842} {Pfam: Pancreatic hormone peptide [PF00159.20, score=37.0]} {RNA1509_15391, RNA1509_36078, RNA1509_47628} {RNA1310_43859, RNA1509_15391, RNA1509_36078, RNA1509_47628} {RNA1509_15391, RNA1509_36078, RNA1509_47628, RNA815_26881}
21. MligTC455_53774 2623 54.65 Mlig455_039561, Mlig455_051366

Neo: -

Age: logFC(26M/2M)=-0.322

Region-enriched R4: 1.262/0.01773

SPATA6 0.965 - - - - 0.965 -

Mlig455_039561 {REF} {Length: 2532} {TRANSSPLICED} {Pfam: Spermatogenesis-assoc protein 6 [PF14909.8, score=115.4]} {Human: ENSG00000132122, SPATA6, spermatogenesis associated 6, [RH, Score=105, Expect=4e-24]} {Mouse: ENSMUSG00000034401, Spata6, spermatogenesis associated 6, [RH, Score=99.0, Expect=4e-22]} {Smed: dd_Smed_v6_10543_0_1, dd_Smed_v6_10543_0_1, [Score=184, Expect=5e-55]} {RNA1509_28452, RNA1509_48064, RNA1509_8673} {RNA1310_20192, RNA1509_28452, RNA1509_48064} {RNA1509_28452, RNA1509_48064, RNA815_23278}

Mlig455_051366 {REF} {Length: 2585} {TRANSSPLICED} {Pfam: Spermatogenesis-assoc protein 6 [PF14909.8, score=114.8]} {Human: ENSG00000132122, SPATA6, spermatogenesis associated 6, [RH, Score=105, Expect=5e-24]} {Mouse: ENSMUSG00000034401, Spata6, spermatogenesis associated 6, [RH, Score=95.5, Expect=6e-21]} {Smed: dd_Smed_v6_10543_0_1, dd_Smed_v6_10543_0_1, [Score=184, Expect=6e-55]} {RNA1509_32010, RNA1509_32967, RNA1509_8673} {RNA1310_20192, RNA1509_32010, RNA1509_32967, RNA1509_8673} {RNA1509_32010, RNA1509_32967, RNA1509_8673, RNA815_17748}
22. MligTC455_33343 459 9.56 Mlig455_063303

Neo: -

Age: -

Region-enriched R2: 1.600/0.01675

ITPR1 0.964 - - - - 0.964 - Mlig455_063303 {REF} {Length: 3962} {Pfam: RyR and IP3R Homology associated [PF08454.13, score=68.3]; Ion transport protein [PF00520.33, score=28.7]} {Human: ENSG00000150995, ITPR1, inositol 1,4,5-trisphosphate receptor type 1, [Score=166, Expect=6e-41]} {Mouse: ENSMUSG00000030102, Itpr1, inositol 1,4,5-trisphosphate receptor 1, [Score=182, Expect=7e-46]} {Dmel: FBgn0010051, Itp-r83A, Inositol 1,4,5,-tris-phosphate receptor, [Score=179, Expect=4e-45]} {Celegans: WBGene00002173, itr-1, Inositol 1,4,5-trisphosphate receptor itr-1, [Score=155, Expect=5e-38]} {Smed: dd_Smed_v6_3814_1_1, dd_Smed_v6_3814_1_1, [Score=1044, Expect=0.0]} {RNA1509_30811} {RNA1310_939} {RNA815_220}
23. MligTC455_41650 752 15.67 Mlig455_020540, Mlig455_020590, Mlig455_020592

Neo: -

Age: -

ARMC9 0.964 - - - - 0.964 -

Mlig455_020540 {REF} {Length: 3118} {TRANSSPLICED} {Human: ENSG00000135931, ARMC9, armadillo repeat containing 9, [RH, Score=537, Expect=0.0]} {Mouse: ENSMUSG00000062590, Armc9, armadillo repeat containing 9, [RH, Score=533, Expect=3e-178]} {Smed: dd_Smed_v6_10926_0_1, dd_Smed_v6_10926_0_1, [RH, Score=498, Expect=8e-166]} {RNA1509_54977, RNA1509_9388} {RNA1310_10290, RNA1509_54977} {RNA1509_54977, RNA815_4141}

Mlig455_020590 {REF} {Length: 2939} {TRANSSPLICED} {Human: ENSG00000135931, ARMC9, armadillo repeat containing 9, [RH, Score=539, Expect=0.0]} {Mouse: ENSMUSG00000062590, Armc9, armadillo repeat containing 9, [RH, Score=531, Expect=8e-178]} {Smed: dd_Smed_v6_10926_0_1, dd_Smed_v6_10926_0_1, [RH, Score=499, Expect=3e-166]} {RNA1509_9388} {RNA1310_10290} {RNA815_4141}

Mlig455_020592 {REF} {Length: 1875} {Pfam: HEAT repeat [PF02985.24, score=19.7]} {Human: ENSG00000135931, ARMC9, armadillo repeat containing 9, [Score=227, Expect=3e-66]} {Mouse: ENSMUSG00000062590, Armc9, armadillo repeat containing 9, [Score=225, Expect=1e-65]} {Smed: dd_Smed_v6_10926_0_1, dd_Smed_v6_10926_0_1, [Score=219, Expect=4e-64]} {RNA1509_9388} {RNA1310_10290} {RNA815_4141}
24. MligTC455_31890 210 4.38 Mlig455_070942

Neo: -

Age: logFC(26M/2M)=-0.564

0.963 - - - - 0.963 - Mlig455_070942 {REF} {Length: 2335} {Pfam: MULE transposase domain [PF10551.11, score=21.4]; Domain of unknown function (DUF4806) [PF16064.7, score=19.0]} {Smed: dd_Smed_v6_24877_0_1, dd_Smed_v6_24877_0_1, [Score=52.0, Expect=2e-08]} {RNA1509_28268} {RNA1310_1293.1} {RNA815_1077}
25. MligTC455_33802 659 13.73 Mlig455_033383

Neo: -

Age: logFC(26M/2M)=-0.359

0.963 - - - - 0.963 - Mlig455_033383 {REF} {Length: 3524} {RNA1509_14410, RNA1509_56133} {RNA1310_8398, RNA1509_56133} {RNA1509_56133, RNA815_14639}
26. MligTC455_50750 137 2.86 Mlig455_004587

Neo: -

Age: -

GNB5 0.963 - - - - 0.963 - Mlig455_004587 {REF} {Length: 6245} {Pfam: WD domain, G-beta repeat [PF00400.34, score=96.6]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=48.4]; Eukaryotic translation initiation factor eIF2A [PF08662.13, score=26.3]; WD40-like domain [PF17005.7, score=24.1]} {Human: ENSG00000069966, GNB5, G protein subunit beta 5, [Score=411, Expect=2e-144]} {Mouse: ENSMUSG00000032192, Gnb5, guanine nucleotide binding protein (G protein), beta 5, [Score=412, Expect=9e-145]} {Dmel: FBgn0030011, Gbeta5, [Score=430, Expect=4e-152]} {Celegans: WBGene00001680, gpb-2, Guanine nucleotide-binding protein subunit beta-2, [Score=402, Expect=6e-141]} {Smed: dd_Smed_v6_10481_0_1, dd_Smed_v6_10481_0_1, [Score=476, Expect=9e-171]} {RNA1509_51468} {RNA1310_13844.1} {RNA815_14582}
27. MligTC455_24058 874 18.21 Mlig455_049588

Neo: -

Age: logFC(26M/2M)=0.283

SYTL4 0.961 - - - - 0.961 - Mlig455_049588 {REF} {Length: 12642} {TRANSSPLICED} {Pfam: C2 domain [PF00168.32, score=68.1]; FYVE-type zinc finger [PF02318.18, score=53.4]; Protein of unknown function (DUF3139) [PF11337.10, score=20.6]} {Human: ENSG00000102362, SYTL4, synaptotagmin like 4, [Score=100, Expect=3e-20]; ENSG00000147041, SYTL5, synaptotagmin like 5, [Score=99.0, Expect=1e-19]} {Mouse: ENSMUSG00000031255, Sytl4, synaptotagmin-like 4, [Score=100, Expect=3e-20]} {Dmel: FBgn0266756, btsz, bitesize, [Score=117, Expect=2e-25]} {Celegans: WBGene00004923, snt-3, SyNapTotagmin, [Score=57.8, Expect=5e-08]} {Smed: dd_Smed_v6_4335_0_1, dd_Smed_v6_4335_0_1, [Score=84.7, Expect=5e-16]} {RNA1509_12528, RNA1509_2527} {RNA1310_245.3, RNA1509_12528} {RNA1509_12528, RNA815_559.1}
28. MligTC455_28901 2683 55.89 Mlig455_000702, Mlig455_000756

Neo: -

Age: -

CNTRL 0.961 - - - - 0.961 -

Mlig455_000702 {REF} {Length: 7735} {TRANSSPLICED} {Pfam: Leucine-rich repeat [PF14580.8, score=68.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=62.9]; Leucine rich repeat [PF13855.8, score=47.3]; Crescentin protein [PF19220.2, score=23.5]} {Human: ENSG00000119397, CNTRL, centriolin, [Score=217, Expect=9e-56]} {Mouse: ENSMUSG00000057110, Cntrl, centriolin, [Score=217, Expect=7e-56]} {Dmel: FBgn0032163, TbCMF46, [Score=85.5, Expect=3e-16]} {Celegans: WBGene00015516, C06A8.6, [Score=78.2, Expect=1e-14]} {Smed: dd_Smed_v6_10369_0_1, dd_Smed_v6_10369_0_1, [Score=189, Expect=6e-48]} {RNA1509_7114} {RNA1310_12566} {RNA815_3884}

Mlig455_000756 {REF} {Length: 7584} {TRANSSPLICED} {Pfam: Leucine-rich repeat [PF14580.8, score=65.5]; Leucine Rich repeats (2 copies) [PF12799.9, score=61.9]; Leucine rich repeat [PF13855.8, score=45.8]} {Human: ENSG00000119397, CNTRL, centriolin, [RH, Score=254, Expect=4e-67]} {Mouse: ENSMUSG00000057110, Cntrl, centriolin, [RH, Score=257, Expect=4e-68]} {Dmel: FBgn0032163, TbCMF46, [Score=84.7, Expect=4e-16]} {Celegans: WBGene00015516, C06A8.6, [Score=78.2, Expect=1e-14]} {Smed: dd_Smed_v6_10369_0_1, dd_Smed_v6_10369_0_1, [RH, Score=199, Expect=9e-51]} {RNA1509_40686, RNA1509_7114} {RNA1310_1213, RNA1509_40686} {RNA1509_40686, RNA815_4518}
29. MligTC455_16252 422 8.8 Mlig455_047309

Neo: -

Age: Down-Up-Up

GRIK3 0.96 - - - - 0.960 - Mlig455_047309 {REF} {Length: 3394} {Pfam: Ligand-gated ion channel [PF00060.28, score=64.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=31.1]; S1 RNA binding domain [PF00575.25, score=19.2]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=85.5, Expect=2e-16]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=85.1, Expect=3e-16]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=84.0, Expect=7e-16]} {Mouse: ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=88.2, Expect=2e-17]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=84.3, Expect=4e-16]} {Dmel: FBgn0038840, Grik, [Score=71.6, Expect=2e-12]} {Smed: dd_Smed_v6_10048_0_1, dd_Smed_v6_10048_0_1, [RH, Score=105, Expect=5e-23]} {RNA1509_9480} {RNA1310_5319.1, RNA1509_9480} {RNA1509_9480, RNA815_1612}
30. MligTC455_23813 678 14.13 Mlig455_000199

Neo: -

Age: Up-Down-Up

FOXF2 0.959 - - 0.959 - - - Mlig455_000199 {REF} {Length: 2173} {Pfam: Forkhead domain [PF00250.20, score=121.5]} {Human: ENSG00000137273, FOXF2, forkhead box F2, [RH, Score=175, Expect=8e-49]} {Mouse: ENSMUSG00000038402, Foxf2, forkhead box F2, [RH, Score=178, Expect=4e-50]} {Dmel: FBgn0045759, bin, biniou, [RH, Score=163, Expect=4e-43]} {Celegans: WBGene00002601, let-381, [RH, Score=169, Expect=7e-48]} {Smed: dd_Smed_v6_15035_0_1, dd_Smed_v6_15035_0_1, [RH, Score=171, Expect=3e-50]} {RNA1509_14169} {RNA1310_28087} {RNA815_25988}
31. MligTC455_42820 154 3.21 Mlig455_029557

Neo: -

Age: -

LARGE1 0.958 - - - - 0.958 - Mlig455_029557 {REF} {Length: 1795} {Pfam: Glycosyl-transferase for dystroglycan [PF13896.8, score=135.5]} {Human: ENSG00000133424, LARGE1, LARGE xylosyl- and glucuronyltransferase 1, [Score=262, Expect=4e-82]} {Mouse: ENSMUSG00000004383, Large1, LARGE xylosyl- and glucuronyltransferase 1, [Score=262, Expect=8e-82]; ENSMUSG00000040434, Large2, LARGE xylosyl- and glucuronyltransferase 2, [Score=258, Expect=4e-81]} {Dmel: FBgn0032457, CG15483, [Score=62.8, Expect=7e-11]} {Celegans: WBGene00010716, lge-1, Glycosyltransferase-like protein LARGE, [Score=127, Expect=5e-33]} {Smed: dd_Smed_v6_15269_0_1, dd_Smed_v6_15269_0_1, [Score=290, Expect=2e-95]} {RNA1509_47482} {RNA1310_56850.2} {RNA815_37190}
32. MligTC455_42821 155 3.22 Mlig455_040440

Neo: -

Age: -

LARGE1 0.958 - - - - 0.958 - Mlig455_040440 {REF} {Length: 5152} {TRANSSPLICED} {Pfam: Glycosyl-transferase for dystroglycan [PF13896.8, score=181.1]; Glycosyl transferase family 8 [PF01501.22, score=52.6]} {Human: ENSG00000133424, LARGE1, LARGE xylosyl- and glucuronyltransferase 1, [RH, Score=649, Expect=0.0]; ENSG00000165905, LARGE2, LARGE xylosyl- and glucuronyltransferase 2, [RH, Score=620, Expect=0.0]} {Mouse: ENSMUSG00000004383, Large1, LARGE xylosyl- and glucuronyltransferase 1, [RH, Score=646, Expect=0.0]; ENSMUSG00000040434, Large2, LARGE xylosyl- and glucuronyltransferase 2, [RH, Score=622, Expect=0.0]} {Dmel: FBgn0032457, CG15483, [RH, Score=67.8, Expect=1e-11]} {Celegans: WBGene00010716, lge-1, Glycosyltransferase-like protein LARGE, [RH, Score=304, Expect=1e-93]} {Smed: dd_Smed_v6_15269_0_1, dd_Smed_v6_15269_0_1, [RH, Score=484, Expect=6e-165]} {RNA1509_51185} {RNA1310_11436, RNA1509_51185} {RNA1509_51185, RNA815_10031}
33. MligTC455_49384 1126 23.47 Mlig455_032243

Neo: -

Age: -

TTC21B 0.957 - - - - 0.957 - Mlig455_032243 {REF} {Length: 4304} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF14559.8, score=148.6]; Tetratricopeptide repeat [PF13428.8, score=118.3]; Tetratricopeptide repeat [PF13432.8, score=97.8]; Tetratricopeptide repeat [PF07719.19, score=94.0]; Anaphase-promoting complex, cyclosome, subunit 3 [PF12895.9, score=69.9]; Tetratricopeptide repeat [PF13181.8, score=65.7]; Tetratricopeptide repeat [PF00515.30, score=65.6]; Tetratricopeptide repeat [PF13424.8, score=52.0]; Tetratricopeptide repeat [PF13174.8, score=47.6]; Tetratricopeptide repeat-like domain [PF09976.11, score=37.9]; TPR repeat [PF13414.8, score=37.0]; Tetratricopeptide repeat [PF13176.8, score=35.6]; Tetratricopeptide repeat [PF13431.8, score=35.4]; Tetratricopeptide repeat [PF13371.8, score=27.1]; NMDA receptor-regulated protein 1 [PF12569.10, score=22.2]} {Human: ENSG00000123607, TTC21B, tetratricopeptide repeat domain 21B, [RH, Score=1110, Expect=0.0]} {Mouse: ENSMUSG00000034848, Ttc21b, tetratricopeptide repeat domain 21B, [RH, Score=1082, Expect=0.0]} {Celegans: WBGene00022696, ZK328.7, Tetratricopeptide repeat protein 21 homolog, [RH, Score=472, Expect=4e-144]} {Smed: dd_Smed_v6_12056_0_1, dd_Smed_v6_12056_0_1, [RH, Score=1029, Expect=0.0]} {RNA1509_12325, RNA1509_7191} {RNA1310_1950, RNA1509_12325, RNA1509_7191} {RNA1509_12325, RNA1509_7191, RNA815_557}
34. MligTC455_23234 347 7.22 Mlig455_006721

Neo: -

Age: -

0.956 - - - - 0.956 - Mlig455_006721 {REF} {Length: 6078} {Smed: dd_Smed_v6_2802_0_1, dd_Smed_v6_2802_0_1, [RH, Score=584, Expect=0.0]} {RNA1509_1489, RNA1509_26881} {RNA1310_997.1, RNA1509_1489, RNA1509_26881} {RNA1509_1489, RNA1509_26881, RNA815_1017.1}
35. MligTC455_36816 362 7.54 Mlig455_027841, Mlig455_060008

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.712

ANK3 0.956 - - - - 0.956 -

Mlig455_027841 {REF} {Length: 5725} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=91.6]; Protein of unknown function (DUF3421) [PF11901.10, score=84.7]; Ankyrin repeats (many copies) [PF13637.8, score=72.1]; Ankyrin repeats (many copies) [PF13857.8, score=49.2]; Ankyrin repeat [PF13606.8, score=41.0]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=55.5, Expect=1e-06]} {Mouse: ENSMUSG00000052331, Ankrd44, ankyrin repeat domain 44, [Score=62.4, Expect=5e-09]} {Dmel: FBgn0034583, CG10527, [Score=93.6, Expect=3e-20]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=81.3, Expect=5e-15]} {Smed: dd_Smed_v6_766_0_1, dd_Smed_v6_766_0_1, [Score=118, Expect=2e-30]} {RNA1509_30268} {RNA1310_2381} {RNA815_861}

Mlig455_060008 {REF} {Length: 4931} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=93.3]; Ankyrin repeats (many copies) [PF13637.8, score=74.1]; Ankyrin repeats (many copies) [PF13857.8, score=51.3]; Ankyrin repeat [PF13606.8, score=43.0]; Ankyrin repeat [PF00023.32, score=19.4]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=53.5, Expect=3e-06]} {Mouse: ENSMUSG00000052331, Ankrd44, ankyrin repeat domain 44, [Score=61.2, Expect=8e-09]} {Dmel: FBgn0016920, nompC, no mechanoreceptor potential C, [Score=52.0, Expect=5e-06]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=80.5, Expect=8e-15]} {Smed: dd_Smed_v6_13721_0_1, dd_Smed_v6_13721_0_1, [Score=59.3, Expect=1e-08]} {RNA1509_30268} {RNA1310_2381} {RNA815_861}
36. MligTC455_33131 549 11.45 Mlig455_022594, Mlig455_026005, Mlig455_070429

Neo: Germline

Age: logFC(26M/2M)=-0.432

KY 0.955 - - - - 0.955 -

Mlig455_022594 {REF} {Length: 667} {Pfam: Helix-turn-helix domain of transposase family ISL3 [PF13542.8, score=27.8]} {RNA1509_53064} {RNA1310_18119} {RNA815_4493}

Mlig455_026005 {REF} {Length: 5002} {Pfam: Transglutaminase-like superfamily [PF01841.21, score=25.4]} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=94.7, Expect=2e-19]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=95.5, Expect=1e-19]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=105, Expect=1e-22]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=105, Expect=2e-23]} {Smed: dd_Smed_v6_5330_0_1, dd_Smed_v6_5330_0_1, [Score=111, Expect=1e-24]} {RNA1509_11170} {RNA1310_2597.1} {RNA815_17158}

Mlig455_070429 {REF} {Length: 5697} {Pfam: Transglutaminase-like superfamily [PF01841.21, score=25.4]} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=97.4, Expect=5e-20]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=96.7, Expect=6e-20]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=113, Expect=4e-25]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=113, Expect=3e-25]} {Smed: dd_Smed_v6_5330_0_1, dd_Smed_v6_5330_0_1, [Score=113, Expect=4e-25]} {RNA1509_11170, RNA1509_29877} {RNA1310_2597.1, RNA1509_11170, RNA1509_29877} {RNA1509_11170, RNA1509_29877, RNA815_3609}
37. MligTC455_35639 3666 76.37 Mlig455_053362

Neo: -

Age: Down-Up-Up

UBE2A 0.955 - - - - 0.955 - Mlig455_053362 {REF} {Length: 1192} {TRANSSPLICED} {Pfam: Ubiquitin-conjugating enzyme [PF00179.28, score=178.1]} {Human: ENSG00000077721, UBE2A, ubiquitin conjugating enzyme E2 A, [RH, Score=270, Expect=6e-94]; ENSG00000119048, UBE2B, ubiquitin conjugating enzyme E2 B, [RH, Score=268, Expect=2e-93]} {Mouse: ENSMUSG00000016308, Ube2a, ubiquitin-conjugating enzyme E2A, [RH, Score=270, Expect=4e-94]; ENSMUSG00000020390, Ube2b, ubiquitin-conjugating enzyme E2B, [RH, Score=268, Expect=2e-93]} {Dmel: FBgn0004436, Ubc6, Ubiquitin conjugating enzyme 6, [RH, Score=258, Expect=2e-89]} {Celegans: WBGene00006701, ubc-1, Ubiquitin-conjugating enzyme E2 1, [RH, Score=268, Expect=4e-93]} {Smed: dd_Smed_v6_3543_0_1, dd_Smed_v6_3543_0_1, [RH, Score=244, Expect=2e-84]} {RNA1509_17248, RNA1509_28415, RNA1509_56837, RNA1509_6326} {RNA1310_29040.1, RNA1509_17248, RNA1509_28415, RNA1509_56837, RNA1509_6326} {RNA1509_17248, RNA1509_28415, RNA1509_56837, RNA1509_6326, RNA815_13231}
38. MligTC455_46559 1484 30.91 Mlig455_056465

Neo: -

Age: logFC(26M/2M)=-0.295

TANC1 0.955 - - - - 0.955 - Mlig455_056465 {REF} {Length: 2067} {Pfam: Ankyrin repeats (many copies) [PF13857.8, score=50.7]; Ankyrin repeats (3 copies) [PF12796.9, score=48.4]; Ankyrin repeat [PF13606.8, score=41.8]; Ankyrin repeats (many copies) [PF13637.8, score=41.1]; Ankyrin repeat [PF00023.32, score=36.6]} {Human: ENSG00000115183, TANC1, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1, [Score=57.0, Expect=5e-08]; ENSG00000145362, ANK2, ankyrin 2, [Score=57.0, Expect=5e-08]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=55.8, Expect=9e-08]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=58.2, Expect=1e-08]} {Smed: dd_Smed_v6_13251_0_1, dd_Smed_v6_13251_0_1, [Score=53.1, Expect=1e-07]} {RNA1509_19702, RNA1509_36019, RNA1509_36843, RNA1509_6963} {RNA1310_14830, RNA1509_36019, RNA1509_36843, RNA1509_6963} {RNA1509_36019, RNA1509_36843, RNA1509_6963, RNA815_5101}
39. MligTC455_44971 99 2.07 Mlig455_055696

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.674

Region-enriched R4: 4.753/0.00442

ATP1B1 0.952 - - - - 0.952 - Mlig455_055696 {REF} {Length: 2498} {TRANSSPLICED} {Pfam: Sodium / potassium ATPase beta chain [PF00287.20, score=206.1]} {Human: ENSG00000143153, ATP1B1, ATPase Na+/K+ transporting subunit beta 1, [RH, Score=125, Expect=7e-33]} {Mouse: ENSMUSG00000026576, Atp1b1, ATPase, Na+/K+ transporting, beta 1 polypeptide, [RH, Score=127, Expect=8e-34]} {Dmel: FBgn0032946, nrv3, nervana 3, [RH, Score=164, Expect=8e-48]} {Celegans: WBGene00007646, nkb-1, Sodium/potassium-transporting ATPase subunit beta-1, [Score=151, Expect=4e-43]} {Smed: dd_Smed_v6_7917_0_1, dd_Smed_v6_7917_0_1, [RH, Score=244, Expect=2e-79]} {RNA1509_10526} {RNA1310_27937} {RNA815_16874}
40. MligTC455_50375 2086 43.45 Mlig455_016459, Mlig455_016525, Mlig455_049814

Neo: -

Age: -

0.952 - - - - 0.952 -

Mlig455_016459 {REF} {Length: 2149} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=23.2]; Ankyrin repeats (many copies) [PF13637.8, score=20.7]} {Smed: dd_Smed_v6_17861_0_1, dd_Smed_v6_17861_0_1, [RH, Score=120, Expect=2e-30]} {RNA1509_10140} {RNA1310_11634.1} {RNA815_4167}

Mlig455_016525 {REF} {Length: 2207} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=23.2]; Ankyrin repeats (many copies) [PF13637.8, score=20.7]} {Smed: dd_Smed_v6_17861_0_1, dd_Smed_v6_17861_0_1, [RH, Score=120, Expect=2e-30]} {RNA1509_10140, RNA1509_60156} {RNA1310_11634.1, RNA1509_10140, RNA1509_60156} {RNA1509_10140, RNA1509_60156, RNA815_4167}

Mlig455_049814 {REF} {Length: 2210} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=23.2]; Ankyrin repeats (many copies) [PF13637.8, score=20.7]} {Smed: dd_Smed_v6_17861_0_1, dd_Smed_v6_17861_0_1, [RH, Score=120, Expect=2e-30]} {RNA1509_10140} {RNA1310_11634.1} {RNA815_4167}
41. MligTC455_23002 1386 28.88 Mlig455_066079, Mlig455_066121

Neo: -

Age: Down-Down-Up

ANKRD50 0.951 - - - - 0.951 -

Mlig455_066079 {REF} {Length: 4539} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=152.7]; Ankyrin repeats (many copies) [PF13637.8, score=140.9]; Ankyrin repeat [PF13606.8, score=112.2]; Ankyrin repeat [PF00023.32, score=105.1]; Ankyrin repeats (many copies) [PF13857.8, score=100.0]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=134, Expect=8e-34]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=131, Expect=4e-33]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=114, Expect=3e-27]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=108, Expect=1e-25]} {Smed: dd_Smed_v6_6779_0_1, dd_Smed_v6_6779_0_1, [Score=117, Expect=1e-28]} {RNA1509_33878, RNA1509_47884, RNA1509_50045, RNA1509_5303} {RNA1310_6276, RNA1509_33878, RNA1509_47884, RNA1509_50045} {RNA1509_33878, RNA1509_47884, RNA1509_50045, RNA815_1153}

Mlig455_066121 {REF} {Length: 4098} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=236.7]; Ankyrin repeats (many copies) [PF13637.8, score=202.9]; Protein kinase domain [PF00069.27, score=191.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=162.2]; Ankyrin repeat [PF13606.8, score=159.1]; Ankyrin repeat [PF00023.32, score=144.3]; Ankyrin repeats (many copies) [PF13857.8, score=135.5]; ABC1 atypical kinase-like domain [PF03109.18, score=32.5]; Fungal protein kinase [PF17667.3, score=31.9]; Kinase-like [PF14531.8, score=28.5]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=203, Expect=4e-53]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=201, Expect=1e-52]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=158, Expect=3e-39]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=157, Expect=5e-39]} {Smed: dd_Smed_v6_11663_0_4, dd_Smed_v6_11663_0_4, [Score=198, Expect=2e-53]} {RNA1509_5303} {RNA1310_6276} {RNA815_1153}
42. MligTC455_23278 386 8.04 Mlig455_037778

Neo: -

Age: logFC(26M/2M)=-0.605

SLC13A3 0.951 - - - - 0.951 - Mlig455_037778 {REF} {Length: 3476} {Pfam: Sodium:sulfate symporter transmembrane region [PF00939.21, score=294.2]; Citrate transporter [PF03600.18, score=99.7]} {Human: ENSG00000158296, SLC13A3, solute carrier family 13 member 3, [Score=377, Expect=4e-121]} {Mouse: ENSMUSG00000018459, Slc13a3, solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3, [Score=367, Expect=1e-117]; ENSMUSG00000001095, Slc13a2, solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2, [Score=359, Expect=9e-115]} {Dmel: FBgn0036816, Indy, I'm not dead yet, [Score=175, Expect=1e-46]} {Celegans: WBGene00007138, B0285.6, Uncharacterized transporter B0285.6, [Score=194, Expect=2e-53]} {Smed: dd_Smed_v6_5476_0_1, dd_Smed_v6_5476_0_1, [Score=315, Expect=3e-98]} {RNA1509_1723, RNA1509_48306} {RNA1310_5497, RNA1509_48306} {RNA1509_48306, RNA815_1709}
43. MligTC455_37342 203 4.23 Mlig455_024018

Neo: -

Age: -

0.951 - - - - 0.951 - Mlig455_024018 {REF} {Length: 1374} {RNA1509_59718} {RNA1310_33285} {RNA815_22262}
44. MligTC455_46255 2218 46.21 Mlig455_024833

Neo: -

Age: logFC(26M/2M)=-0.329

CASC1 0.951 - - - - 0.951 - Mlig455_024833 {REF} {Length: 2822} {Pfam: Cancer susceptibility candidate 1 N-terminus [PF15927.7, score=170.2]; Cancer susceptibility candidate 1 C-terminal [PF12366.10, score=30.7]} {Human: ENSG00000118307, CASC1, cancer susceptibility 1, [RH, Score=319, Expect=1e-97]} {Mouse: ENSMUSG00000043541, Casc1, cancer susceptibility candidate 1, [RH, Score=293, Expect=5e-88]} {Dmel: FBgn0030889, CG15373, [RH, Score=82.4, Expect=8e-16]} {Smed: dd_Smed_v6_11291_0_1, dd_Smed_v6_11291_0_1, [RH, Score=521, Expect=7e-175]} {RNA1509_1842} {RNA1310_6962.1} {RNA815_2139}
45. MligTC455_19430 476 9.92 Mlig455_059737

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.749

Region-enriched R2: 1.435/0.03961

WDR49 0.95 - - - - 0.950 - Mlig455_059737 {REF} {Length: 4068} {Pfam: WD domain, G-beta repeat [PF00400.34, score=25.0]} {Human: ENSG00000174776, WDR49, WD repeat domain 49, [Score=140, Expect=3e-35]} {Mouse: ENSMUSG00000104301, Wdr49, WD repeat domain 49, [Score=130, Expect=1e-31]} {Smed: dd_Smed_v6_5437_0_2, dd_Smed_v6_5437_0_2, [Score=132, Expect=1e-32]} {RNA1509_29401, RNA1509_3708} {RNA1310_2384.2, RNA1509_29401} {RNA1509_29401, RNA815_724.1}
46. MligTC455_30290 738 15.38 Mlig455_023808

Neo: -

Age: Up-Down-Up

DST 0.95 - - - - 0.950 - Mlig455_023808 {REF} {Length: 23754} {Pfam: Domain of unknown function (DUF1851) [PF08906.13, score=48.1]; D-amino acid oxidase activator [PF15199.8, score=40.8]; SH3 domain [PF17902.3, score=39.4]; Carbohydrate/starch-binding module (family 21) [PF03370.15, score=28.2]} {Human: ENSG00000151914, DST, dystonin, [RH, Score=74.7, Expect=2e-12]} {Mouse: ENSMUSG00000026131, Dst, dystonin, [RH, Score=73.6, Expect=4e-12]} {Dmel: FBgn0013733, shot, short stop, [Score=87.0, Expect=2e-16]} {Celegans: WBGene00006876, vab-10, VAB-10B protein, [Score=52.4, Expect=5e-06]} {Smed: dd_Smed_v6_8220_0_4, dd_Smed_v6_8220_0_4, [Score=160, Expect=4e-39]} {RNA1509_41993} {RNA1310_3340.2} {RNA815_578.1}

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