Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_44344 | 105 | 2.18 | Mlig455_034809 | Neo: - Age: - Region-enriched R2: 4.521/0.01555 |
ECE2 | Mlig455_034809 {REF} {Length: 2882} {Pfam: Peptidase family M13 [PF05649.15, score=83.7]; Peptidase family M13 [PF01431.23, score=48.1]} {Human: ENSG00000145194, ECE2, endothelin converting enzyme 2, [Score=131, Expect=7e-31]; ENSG00000284917, EEF1AKMT4-ECE2, EEF1AKMT4-ECE2 readthrough, [Score=130, Expect=1e-30]} {Mouse: ENSMUSG00000115293, Gm49333, predicted gene, 49333, [Score=127, Expect=9e-30]; ENSMUSG00000022842, Ece2, endothelin converting enzyme 2, [Score=127, Expect=1e-29]} {Dmel: FBgn0029843, Nep1, Neprilysin 1, [Score=108, Expect=8e-24]} {Celegans: WBGene00017842, nep-12, NEPrilysin metallopeptidase family, [Score=106, Expect=2e-23]} {Smed: dd_Smed_v6_30500_0_1, dd_Smed_v6_30500_0_1, [RH, Score=60.1, Expect=2e-09]} {RNA1310_33925} {RNA815_33631} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -6.776 | 1.907 | 0.99976 | 1.00000 | |
RegionR2 | 4.521 | 1.907 | 0.00062 | 0.01555 | |
RegionR3 | 1.609 | 1.907 | 0.29630 | 0.83805 | |
RegionR4 | -0.093 | 1.907 | 0.80450 | 1.00000 | |
RegionR5 | 1.45 | 1.907 | 0.30536 | 0.64213 | |
RegionR6 | 2.542 | 1.907 | 0.07126 | 0.49718 | |
RegionR7 | 1.78 | 1.907 | 0.26919 | 0.90057 | |
RegionR8 | -5.032 | 1.907 | 1.00000 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -0.122 | 1.907 | 1.00000 | 1.00000 | |
RegenerationR2 | -0.416 | 1.907 | 0.51246 | 0.87667 | |
RegenerationR3 | 1.778 | 1.907 | 0.07291 | 0.45149 | |
RegenerationR4 | 1.879 | 1.907 | 0.05918 | 0.39055 | |
RegenerationR5 | 1.809 | 1.907 | 0.03769 | 0.32154 | |
RegenerationR6 | 0.106 | 1.907 | 0.91437 | 1.00000 | |
RegenerationBL | -2.799 | 1.907 | 0.99990 | 1.00000 | |
RegenerationTP | 4.231 | 1.907 | 0.02038 | 0.24487 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_44344 | 105 | 2.18 | Mlig455_034809 | Neo: - Age: - Region-enriched R2: 4.521/0.01555 |
ECE2 | 4 | - | - | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_034809 {REF} {Length: 2882} {Pfam: Peptidase family M13 [PF05649.15, score=83.7]; Peptidase family M13 [PF01431.23, score=48.1]} {Human: ENSG00000145194, ECE2, endothelin converting enzyme 2, [Score=131, Expect=7e-31]; ENSG00000284917, EEF1AKMT4-ECE2, EEF1AKMT4-ECE2 readthrough, [Score=130, Expect=1e-30]} {Mouse: ENSMUSG00000115293, Gm49333, predicted gene, 49333, [Score=127, Expect=9e-30]; ENSMUSG00000022842, Ece2, endothelin converting enzyme 2, [Score=127, Expect=1e-29]} {Dmel: FBgn0029843, Nep1, Neprilysin 1, [Score=108, Expect=8e-24]} {Celegans: WBGene00017842, nep-12, NEPrilysin metallopeptidase family, [Score=106, Expect=2e-23]} {Smed: dd_Smed_v6_30500_0_1, dd_Smed_v6_30500_0_1, [RH, Score=60.1, Expect=2e-09]} {RNA1310_33925} {RNA815_33631} |
2. | MligTC455_41035 | 366 | 7.62 | Mlig455_000866 | Neo: - Age: logFC(26M/2M)=-0.773 Region-specific R2: 5.029 Region-enriched R2: 4.768/0.00000 |
1.704 | - | - | 0.730 | - | 0.974 | - | Mlig455_000866 {REF} {Length: 1126} {Pfam: Pancreatic hormone peptide [PF00159.20, score=41.6]} {RNA1509_27581} {RNA1310_74103, RNA1509_27581} {RNA1509_27581, RNA815_38377} | |
3. | MligTC455_15500 | 74 | 1.54 | Mlig455_044618 | Neo: - Age: - |
GABBR2 | 1.682 | - | - | 0.730 | - | 0.952 | - | Mlig455_044618 {REF} {Length: 2484} {Pfam: 7 transmembrane sweet-taste receptor of 3 GCPR [PF00003.24, score=138.4]; Receptor family ligand binding region [PF01094.30, score=57.8]} {Human: ENSG00000136928, GABBR2, gamma-aminobutyric acid type B receptor subunit 2, [Score=184, Expect=2e-48]} {Mouse: ENSMUSG00000039809, Gabbr2, gamma-aminobutyric acid (GABA) B receptor, 2, [Score=182, Expect=8e-48]} {Dmel: FBgn0027575, GABA-B-R2, metabotropic GABA-B receptor subtype 2, [Score=173, Expect=9e-45]} {Celegans: WBGene00022675, gbb-2, GABA B receptor subunit; GABAB2 receptor subunit, [Score=165, Expect=1e-42]} {Smed: dd_Smed_v6_51663_0_1, dd_Smed_v6_51663_0_1, [Score=122, Expect=4e-31]} {RNA1310_32095} {RNA815_22947} |
4. | MligTC455_13537 | 247 | 5.14 | Mlig455_014382 | Neo: - Age: Down-Up-Up |
1.662 | - | - | - | 0.703 | 0.959 | - | Mlig455_014382 {REF} {Length: 1551} {RNA1509_34193} {RNA1310_28373.2, RNA1509_34193} {RNA1509_34193, RNA815_6877.1} | |
5. | MligTC455_31057 | 90 | 1.86 | Mlig455_055485 | Neo: - Age: - Region-enriched R2: 4.086/0.03047 |
0.983 | - | - | - | - | 0.983 | - | Mlig455_055485 {REF} {Length: 2200} {RNA1310_31820} {RNA815_35187} | |
6. | MligTC455_19336 | 106 | 2.22 | Mlig455_043985 | Neo: - |
ANKRD60 | 0.972 | - | - | - | - | 0.972 | - | Mlig455_043985 {REF} {Length: 2392} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=55.8]; Ankyrin repeats (3 copies) [PF12796.9, score=49.1]; Ankyrin repeats (many copies) [PF13857.8, score=48.9]; Ankyrin repeat [PF00023.32, score=47.3]; Ankyrin repeat [PF13606.8, score=44.5]} {Human: ENSG00000124227, ANKRD60, ankyrin repeat domain 60, [Score=84.0, Expect=1e-18]} {Mouse: ENSMUSG00000027517, Ankrd60, ankyrin repeat domain 60, [Score=83.6, Expect=7e-19]} {Dmel: FBgn0011747, Ank, Ankyrin, [Score=70.1, Expect=7e-14]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=57.4, Expect=1e-09]} {Smed: dd_Smed_v6_8330_0_1, dd_Smed_v6_8330_0_1, [Score=177, Expect=8e-54]} {RNA1509_32608} {RNA1310_9165} {RNA815_3110} |
7. | MligTC455_32918 | 3669 | 76.44 | Mlig455_025787, Mlig455_064390 | Neo: - Age: Down-Up-Down, logFC(26M/2M)=-0.366 Region-enriched R2: 1.323/0.03276 Regeneration-depleted R6: -3.552 |
0.97 | - | - | - | 0.970 | - | - | Mlig455_025787 {REF} {Length: 2673} {Pfam: Methyltransferase domain [PF13649.8, score=56.0]; Methyltransferase domain [PF08241.14, score=51.2]; Methyltransferase domain [PF13847.8, score=46.8]; Methyltransferase domain [PF08242.14, score=43.8]; Methyltransferase small domain [PF05175.16, score=38.6]; Methyltransferase domain [PF13489.8, score=29.7]; Nodulation protein S (NodS) [PF05401.13, score=26.7]; Ribosomal protein L11 methyltransferase (PrmA) [PF06325.15, score=25.3]; ubiE/COQ5 methyltransferase family [PF01209.20, score=21.2]; Mycolic acid cyclopropane synthetase [PF02353.22, score=18.1]} {RNA1509_16802} {RNA1310_264.1} {RNA815_16170} Mlig455_064390 {REF} {Length: 2718} {Pfam: Methyltransferase domain [PF13649.8, score=57.4]; Methyltransferase domain [PF08241.14, score=53.0]; Methyltransferase domain [PF13847.8, score=49.7]; Methyltransferase domain [PF08242.14, score=44.4]; Methyltransferase small domain [PF05175.16, score=39.7]; Methyltransferase domain [PF13489.8, score=34.4]; Nodulation protein S (NodS) [PF05401.13, score=27.9]; Ribosomal protein L11 methyltransferase (PrmA) [PF06325.15, score=25.9]; ubiE/COQ5 methyltransferase family [PF01209.20, score=22.7]; Mycolic acid cyclopropane synthetase [PF02353.22, score=18.5]} {Celegans: WBGene00016023, prmt-6, PRotein arginine MethylTransferase, [RH, Score=63.2, Expect=2e-11]} {RNA1509_16802, RNA1509_32668, RNA1509_49406, RNA1509_55622} {RNA1310_14223, RNA1509_16802, RNA1509_32668, RNA1509_49406, RNA1509_55622} {RNA1509_16802, RNA1509_32668, RNA1509_49406, RNA1509_55622, RNA815_16170} |
|
8. | MligTC455_25670 | 56 | 1.17 | Mlig455_002942 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=1.002 Region-enriched R3: 3.168/0.04222 |
0.966 | - | - | - | - | 0.966 | - | Mlig455_002942 {REF} {Length: 2524} {RNA1509_57755} {RNA1310_35856.1} {RNA815_19086} | |
9. | MligTC455_21143 | 296 | 6.18 | Mlig455_016004 | Neo: - Age: logFC(26M/2M)=-0.497 Regeneration-downregulated R6: -2.391 Regeneration-depleted R6: -2.391 |
WNT5A | 0.96 | - | - | - | - | 0.960 | - | Mlig455_016004 {REF} {Length: 3460} {Pfam: wnt family [PF00110.21, score=323.9]} {Human: ENSG00000114251, WNT5A, Wnt family member 5A, [RH, Score=282, Expect=7e-92]; ENSG00000111186, WNT5B, Wnt family member 5B, [RH, Score=280, Expect=4e-91]} {Mouse: ENSMUSG00000021994, Wnt5a, wingless-type MMTV integration site family, member 5A, [RH, Score=283, Expect=1e-92]; ENSMUSG00000030170, Wnt5b, wingless-type MMTV integration site family, member 5B, [RH, Score=277, Expect=4e-90]} {Dmel: FBgn0004360, Wnt2, Wnt oncogene analog 2, [RH, Score=201, Expect=7e-61]} {Celegans: WBGene00000858, cwn-2, [RH, Score=249, Expect=9e-80]} {Smed: dd_Smed_v6_15469_0_1, dd_Smed_v6_15469_0_1, [RH, Score=283, Expect=1e-92]} {RNA1509_15617, RNA1509_43347} {RNA1310_6635.1, RNA1509_15617, RNA1509_43347} {RNA1509_15617, RNA1509_43347, RNA815_13704} |
10. | MligTC455_33370 | 737 | 15.36 | Mlig455_007477, Mlig455_067514 | Neo: - Age: logFC(26M/2M)=0.602 |
0.96 | - | - | - | 0.960 | - | - | Mlig455_007477 {REF} {Length: 3793} {Pfam: DDE superfamily endonuclease [PF13358.8, score=29.4]; Homeodomain-like domain [PF13384.8, score=20.1]} {Smed: dd_Smed_v6_16239_0_2, dd_Smed_v6_16239_0_2, [Score=62.4, Expect=1e-11]} {RNA1509_58678} {RNA1310_7844.1} {RNA815_2198.1} Mlig455_067514 {REF} {Length: 1034} {Pfam: DDE superfamily endonuclease [PF13358.8, score=29.7]; Homeodomain-like domain [PF13384.8, score=20.1]} {Smed: dd_Smed_v6_16239_0_3, dd_Smed_v6_16239_0_3, [Score=62.4, Expect=1e-11]} {RNA1310_122928} |
|
11. | MligTC455_38490 | 38 | 0.8 | Mlig455_028980 | Neo: - Age: Down-Up-Down |
0.96 | - | - | - | - | 0.960 | - | Mlig455_028980 {REF} {Length: 3387} {RNA1509_29504} {RNA1310_1629} {RNA815_5687} | |
12. | MligTC455_50454 | 394 | 8.21 | Mlig455_057487 | Neo: - Age: Down-Up-Up Region-enriched R2: 5.517/0.00000 |
0.959 | - | - | - | - | 0.959 | - | Mlig455_057487 {REF} {Length: 724} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=33.5]; Nematode insulin-related peptide beta type [PF03488.16, score=20.4]} {RNA1509_58074} {RNA1310_51990} {RNA815_25071} | |
13. | MligTC455_15685 | 62 | 1.3 | Mlig455_011329 | Neo: - Age: - |
NOTCH4 | 0.958 | - | - | - | - | 0.958 | - | Mlig455_011329 {REF} {Length: 1536} {Pfam: EGF-like domain [PF00008.29, score=24.1]} {Human: ENSG00000232339, NOTCH4, notch 4, [Score=54.3, Expect=5e-08]; ENSG00000206312, NOTCH4, notch 4, [Score=54.3, Expect=5e-08]; ENSG00000223355, NOTCH4, notch 4, [Score=54.3, Expect=5e-08]; ENSG00000234876, NOTCH4, notch 4, [Score=53.9, Expect=5e-08]; ENSG00000204301, NOTCH4, notch 4, [Score=53.9, Expect=5e-08]; ENSG00000235396, NOTCH4, notch 4, [Score=52.4, Expect=2e-07]; ENSG00000148400, NOTCH1, notch 1, [Score=52.0, Expect=2e-07]} {Mouse: ENSMUSG00000038146, Notch3, notch 3, [Score=53.5, Expect=5e-08]; ENSMUSG00000026923, Notch1, notch 1, [Score=52.0, Expect=2e-07]} {RNA1509_48141} {RNA1310_40191} {RNA815_46710} |
14. | MligTC455_33448 | 77 | 1.61 | Mlig455_023212, Mlig455_037490, Mlig455_053804 | Neo: - Age: Down-Up-Down Region-enriched R2: 4.691/0.03915 |
0.958 | - | - | - | - | 0.958 | - | Mlig455_023212 {REF} {Length: 2266} {TRANSSPLICED} {Pfam: Recombination endonuclease VII [PF02945.17, score=30.6]; DNA polymerase type B, organellar and viral [PF03175.15, score=25.4]} {Celegans: WBGene00016348, C33E10.6, [Score=216, Expect=4e-59]} {Smed: dd_Smed_v6_9974_1_5, dd_Smed_v6_9974_1_5, [Score=200, Expect=4e-55]} {RNA1509_26772} {RNA1310_4650} {RNA815_24522} Mlig455_037490 {REF} {Length: 4620} {TRANSSPLICED} {Pfam: Recombination endonuclease VII [PF02945.17, score=27.4]} {Celegans: WBGene00022511, ZC53.4, [Score=243, Expect=3e-65]} {Smed: dd_Smed_v6_9974_1_2, dd_Smed_v6_9974_1_2, [RH, Score=527, Expect=7e-170]} {RNA1509_26772} {RNA1310_4650, RNA1509_26772} {RNA1509_26772, RNA815_12457} Mlig455_053804 {REF} {Length: 4594} {TRANSSPLICED} {Pfam: Recombination endonuclease VII [PF02945.17, score=27.7]} {Celegans: WBGene00022511, ZC53.4, [Score=245, Expect=6e-66]} {Smed: dd_Smed_v6_9974_1_2, dd_Smed_v6_9974_1_2, [RH, Score=532, Expect=8e-172]} {RNA1509_26772} {RNA1310_4650} {RNA815_12457} |
|
15. | MligTC455_13146 | 41 | 0.85 | Mlig455_053132 | Neo: - Age: - |
0.953 | - | - | - | - | 0.953 | - | Mlig455_053132 {REF} {Length: 687} {NoTransDecoderORF} {RNA1509_31190} {RNA1310_29297} {RNA815_21647} | |
16. | MligTC455_30599 | 62 | 1.29 | Mlig455_035018, Mlig455_053448 | Neo: - Age: Up-Down-Up |
CRHR1, LINC02210-CRHR1 | 0.952 | - | - | - | - | 0.952 | - | Mlig455_035018 {REF} {Length: 707} {Pfam: 7 transmembrane receptor (Secretin family) [PF00002.26, score=19.9]} {Human: ENSG00000263715, LINC02210-CRHR1, LINC02210-CRHR1 readthrough, [Score=66.2, Expect=2e-13]; ENSG00000120088, CRHR1, corticotropin releasing hormone receptor 1, [Score=66.2, Expect=5e-13]; ENSG00000278232, CRHR1, corticotropin releasing hormone receptor 1, [Score=66.2, Expect=5e-13]; ENSG00000276191, CRHR1, corticotropin releasing hormone receptor 1, [Score=66.2, Expect=5e-13]} {Mouse: ENSMUSG00000018634, Crhr1, corticotropin releasing hormone receptor 1, [Score=65.5, Expect=8e-13]} {Dmel: FBgn0260753, Pdfr, Pigment-dispersing factor receptor, [Score=65.1, Expect=7e-13]} {Celegans: WBGene00015735, pdfr-1, Calcitonin receptor-like protein 1, [Score=60.1, Expect=3e-11]} {Smed: dd_Smed_v6_22246_0_1, dd_Smed_v6_22246_0_1, [Score=52.0, Expect=1e-08]} {RNA1310_81830} Mlig455_053448 {REF} {Length: 4522} {Pfam: 7 transmembrane receptor (Secretin family) [PF00002.26, score=21.7]} {Human: ENSG00000120088, CRHR1, corticotropin releasing hormone receptor 1, [Score=67.4, Expect=4e-13]; ENSG00000263715, LINC02210-CRHR1, LINC02210-CRHR1 readthrough, [Score=67.4, Expect=1e-13]; ENSG00000278232, CRHR1, corticotropin releasing hormone receptor 1, [Score=67.4, Expect=4e-13]; ENSG00000276191, CRHR1, corticotropin releasing hormone receptor 1, [Score=67.4, Expect=4e-13]} {Mouse: ENSMUSG00000018634, Crhr1, corticotropin releasing hormone receptor 1, [Score=66.6, Expect=5e-13]} {Dmel: FBgn0260753, Pdfr, Pigment-dispersing factor receptor, [Score=63.9, Expect=3e-12]} {Celegans: WBGene00015735, pdfr-1, Calcitonin receptor-like protein 1, [Score=62.0, Expect=1e-11]} {Smed: dd_Smed_v6_22246_0_1, dd_Smed_v6_22246_0_1, [Score=52.4, Expect=2e-08]} {RNA1509_31473} {RNA1310_51110.1} {RNA815_20842.1} |
17. | MligTC455_53637 | 3377 | 70.36 | Mlig455_026738, Mlig455_051749 | Neo: - Age: Down-Down-Up Region-enriched R8: 2.667/0.00000 Regeneration-downregulated BL: -2.506 Regeneration-depleted BL: -2.506 |
0.951 | - | - | - | - | 0.951 | - | Mlig455_026738 {REF} {Length: 1503} {RNA1509_14499} {RNA1310_49321, RNA1509_14499} {RNA1509_14499, RNA815_24877} Mlig455_051749 {REF} {Length: 639} {RNA1509_14499} {RNA1310_49321} {RNA815_24877} |