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Results for MligTC455_45659

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_45659 1015 21.14 Mlig455_064934

Neo: -

Age: -

SPATA6 Mlig455_064934 {REF} {Length: 2158} {TRANSSPLICED} {Pfam: Spermatogenesis-assoc protein 6 [PF14909.8, score=79.4]} {Human: ENSG00000132122, SPATA6, spermatogenesis associated 6, [Score=75.1, Expect=3e-14]} {Mouse: ENSMUSG00000034401, Spata6, spermatogenesis associated 6, [Score=73.9, Expect=7e-14]} {Smed: dd_Smed_v6_10543_0_1, dd_Smed_v6_10543_0_1, [Score=153, Expect=4e-43]} {RNA1509_21442, RNA1509_8489} {RNA1310_11404, RNA1509_21442} {RNA1509_21442, RNA815_25609.1}

Cumulative graph for MligTC455_45659

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.626 4.642 0.49614 1.00000
RegionR2 0.288 4.642 0.48057 0.86466
RegionR3 0.796 4.642 0.01395 0.18900
RegionR4 0.561 4.642 0.19559 0.47371
RegionR5 -0.133 4.642 0.69980 1.00000
RegionR6 -0.071 4.642 0.84431 1.00000
RegionR7 -0.295 4.642 0.49151 1.00000
RegionR8 -0.521 4.642 0.31996 0.95407

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -7.361 4.642 0.05508 0.71346
RegenerationR2 -0.1 4.642 0.78223 0.98393
RegenerationR3 -0.8 4.642 0.04398 0.36642
RegenerationR4 -0.426 4.642 0.32645 0.76250
RegenerationR5 -0.066 4.642 0.86897 1.00000
RegenerationR6 -0.127 4.642 0.76296 0.95786
RegenerationBL -0.144 4.642 0.75621 1.00000
RegenerationTP -0.331 4.642 0.52358 0.91616


Genes with expression patterns similar to MligTC455_45659

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_45659 1015 21.14 Mlig455_064934

Neo: -

Age: -

SPATA6 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_064934 {REF} {Length: 2158} {TRANSSPLICED} {Pfam: Spermatogenesis-assoc protein 6 [PF14909.8, score=79.4]} {Human: ENSG00000132122, SPATA6, spermatogenesis associated 6, [Score=75.1, Expect=3e-14]} {Mouse: ENSMUSG00000034401, Spata6, spermatogenesis associated 6, [Score=73.9, Expect=7e-14]} {Smed: dd_Smed_v6_10543_0_1, dd_Smed_v6_10543_0_1, [Score=153, Expect=4e-43]} {RNA1509_21442, RNA1509_8489} {RNA1310_11404, RNA1509_21442} {RNA1509_21442, RNA815_25609.1}
2. MligTC455_45658 1036 21.58 Mlig455_018899

Neo: -

Age: Down-Down-Up

SPATA6 5.97 1.000 0.997 0.999 0.995 0.984 0.995 Mlig455_018899 {REF} {Length: 2167} {TRANSSPLICED} {Pfam: Spermatogenesis-assoc protein 6 [PF14909.8, score=79.4]} {Human: ENSG00000132122, SPATA6, spermatogenesis associated 6, [Score=75.1, Expect=3e-14]} {Mouse: ENSMUSG00000034401, Spata6, spermatogenesis associated 6, [Score=73.9, Expect=7e-14]} {Smed: dd_Smed_v6_10543_0_1, dd_Smed_v6_10543_0_1, [Score=153, Expect=4e-43]} {RNA1509_8489} {RNA1310_11404, RNA1509_8489} {RNA1509_8489, RNA815_25609.1}
3. MligTC455_52117 1487 30.97 Mlig455_036529

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-1.023

CFAP58 2.5 - 0.823 0.702 - - 0.975 Mlig455_036529 {REF} {Length: 3147} {Pfam: Autophagy protein 16 (ATG16) [PF08614.13, score=22.7]} {Human: ENSG00000120051, CFAP58, cilia and flagella associated protein 58, [RH, Score=920, Expect=0.0]} {Mouse: ENSMUSG00000046585, Cfap58, cilia and flagella associated protein 58, [RH, Score=988, Expect=0.0]} {Dmel: FBgn0039490, CG5882, [RH, Score=162, Expect=8e-41]} {Celegans: WBGene00001328, epi-1, Laminin-like protein epi-1, [Score=56.6, Expect=9e-08]} {Smed: dd_Smed_v6_5727_0_1, dd_Smed_v6_5727_0_1, [RH, Score=1105, Expect=0.0]} {RNA1509_27468, RNA1509_282} {RNA1310_4570, RNA1509_27468} {RNA1509_27468, RNA815_1528}
4. MligTC455_24552 1774 36.95 Mlig455_015821, Mlig455_015828

Neo: -

Age: Up-Up-Up

IQCE 2.428 - 0.737 - 0.727 - 0.964

Mlig455_015821 {REF} {Length: 2698} {TRANSSPLICED} {Pfam: Fez1 [PF06818.17, score=21.8]; IQ calmodulin-binding motif [PF00612.29, score=21.0]} {Human: ENSG00000106012, IQCE, IQ motif containing E, [RH, Score=127, Expect=5e-30]} {Mouse: ENSMUSG00000036555, Iqce, IQ motif containing E, [RH, Score=128, Expect=1e-30]} {Smed: dd_Smed_v6_7345_0_1, dd_Smed_v6_7345_0_1, [RH, Score=73.6, Expect=7e-14]} {RNA1509_3714} {RNA1310_6916.1} {RNA815_2091.1}

Mlig455_015828 {REF} {Length: 2744} {TRANSSPLICED} {Pfam: Fez1 [PF06818.17, score=21.8]; IQ calmodulin-binding motif [PF00612.29, score=21.0]} {Human: ENSG00000106012, IQCE, IQ motif containing E, [RH, Score=127, Expect=5e-30]} {Mouse: ENSMUSG00000036555, Iqce, IQ motif containing E, [RH, Score=128, Expect=1e-30]} {Smed: dd_Smed_v6_7345_0_1, dd_Smed_v6_7345_0_1, [RH, Score=73.6, Expect=7e-14]} {RNA1509_3714} {RNA1310_6916.1, RNA1509_3714} {RNA1509_3714, RNA815_2091.1}
5. MligTC455_33706 819 17.07 Mlig455_008312

Neo: -

Age: -

XRRA1 2.416 - 0.703 0.749 - - 0.964 Mlig455_008312 {REF} {Length: 3552} {Pfam: Leucine Rich repeats (2 copies) [PF12799.9, score=41.9]; Leucine rich repeat [PF13855.8, score=29.4]} {Human: ENSG00000166435, XRRA1, X-ray radiation resistance associated 1, [RH, Score=163, Expect=3e-44]} {Mouse: ENSMUSG00000035211, Xrra1, X-ray radiation resistance associated 1, [RH, Score=171, Expect=1e-43]} {Smed: dd_Smed_v6_13519_0_1, dd_Smed_v6_13519_0_1, [RH, Score=154, Expect=5e-38]} {RNA1509_21148, RNA1509_45583} {RNA1310_16743.1, RNA1509_21148, RNA1509_45583} {RNA1509_21148, RNA1509_45583, RNA815_17679}
6. MligTC455_24553 855 17.8 Mlig455_023662

Neo: -

Age: logFC(26M/2M)=-1.366

IQCE 2.414 - 0.730 - 0.722 - 0.962 Mlig455_023662 {REF} {Length: 4080} {TRANSSPLICED} {Human: ENSG00000106012, IQCE, IQ motif containing E, [Score=102, Expect=4e-23]} {Mouse: ENSMUSG00000036555, Iqce, IQ motif containing E, [Score=102, Expect=5e-23]} {Smed: dd_Smed_v6_7345_0_1, dd_Smed_v6_7345_0_1, [Score=65.1, Expect=1e-11]} {RNA1509_3714} {RNA1310_6916.1} {RNA815_2091.1}
7. MligTC455_44849 3056 63.66 Mlig455_014245

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.313

LEXM 1.827 - 0.870 - - - 0.957 Mlig455_014245 {REF} {Length: 2724} {Human: ENSG00000162398, LEXM, lymphocyte expansion molecule, [RH, Score=169, Expect=2e-47]} {Mouse: ENSMUSG00000054362, Lexm, lymphocyte expansion molecule, [RH, Score=173, Expect=3e-49]} {Smed: dd_Smed_v6_10776_0_1, dd_Smed_v6_10776_0_1, [RH, Score=361, Expect=3e-122]} {RNA1509_2011} {RNA1310_14442.1} {RNA815_5377}
8. MligTC455_22729 1065 22.18 Mlig455_006821, Mlig455_054658

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.317

Region-enriched R2: 1.624/0.00561

DNAH8 1.818 - 0.851 - - - 0.967

Mlig455_006821 {REF} {Length: 14560} {Pfam: Dynein heavy chain, N-terminal region 1 [PF08385.14, score=537.8]; Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=466.2]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=416.8]; Dynein heavy chain C-terminal domain [PF18199.3, score=324.6]; ATP-binding dynein motor region [PF12781.9, score=291.0]; P-loop containing dynein motor region D4 [PF12780.9, score=290.7]; P-loop containing dynein motor region [PF12775.9, score=226.6]; Dynein heavy chain AAA lid domain [PF18198.3, score=177.7]; Microtubule-binding stalk of dynein motor [PF12777.9, score=141.5]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=134.5]; AAA domain (dynein-related subfamily) [PF07728.16, score=81.4]; Dynein heavy chain AAA lid domain [PF17852.3, score=76.3]; AAA+ lid domain [PF17857.3, score=62.9]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=25.1]} {Human: ENSG00000124721, DNAH8, dynein axonemal heavy chain 8, [RH, Score=5670, Expect=0.0]} {Mouse: ENSMUSG00000033826, Dnah8, dynein, axonemal, heavy chain 8, [RH, Score=5682, Expect=0.0]} {Dmel: FBgn0267432, kl-3, male fertility factor kl3, [RH, Score=4460, Expect=0.0]} {Celegans: WBGene00000485, che-3, Cytoplasmic dynein 2 heavy chain 1, [Score=980, Expect=0.0]} {Smed: dd_Smed_v6_4176_0_1, dd_Smed_v6_4176_0_1, [RH, Score=6801, Expect=0.0]} {RNA1509_11311, RNA1509_12955, RNA1509_201, RNA1509_25369, RNA1509_50556, RNA1509_55453} {RNA1310_42, RNA1509_11311, RNA1509_12955, RNA1509_201, RNA1509_25369, RNA1509_50556, RNA1509_55453} {RNA1509_11311, RNA1509_12955, RNA1509_201, RNA1509_25369, RNA1509_50556, RNA1509_55453, RNA815_121}

Mlig455_054658 {REF} {Length: 1087} {Pfam: Phage integrase, N-terminal SAM-like domain [PF13495.8, score=25.6]; Phage integrase, N-terminal SAM-like domain [PF02899.19, score=24.9]} {Human: ENSG00000124721, DNAH8, dynein axonemal heavy chain 8, [RH, Score=59.3, Expect=7e-10]} {Mouse: ENSMUSG00000033826, Dnah8, dynein, axonemal, heavy chain 8, [Score=57.4, Expect=1e-08]} {Smed: dd_Smed_v6_4176_0_1, dd_Smed_v6_4176_0_1, [Score=84.0, Expect=1e-17]} {RNA1509_25369} {RNA1310_25264} {RNA815_121}
9. MligTC455_27708 1033 21.52 Mlig455_058740

Neo: -

Age: Down-Down-Up

TCTN1 1.768 - 0.810 - - - 0.958 Mlig455_058740 {REF} {Length: 4264} {Pfam: Protein of unknown function (DUF1619) [PF07773.13, score=180.3]} {Human: ENSG00000204852, TCTN1, tectonic family member 1, [RH, Score=140, Expect=1e-34]} {Mouse: ENSMUSG00000038593, Tctn1, tectonic family member 1, [RH, Score=128, Expect=8e-31]} {Smed: dd_Smed_v6_14210_0_1, dd_Smed_v6_14210_0_1, [Score=82.4, Expect=2e-16]} {RNA1509_21328, RNA1509_2978, RNA1509_56923, RNA1509_7408} {RNA1310_313, RNA1509_2978, RNA1509_56923, RNA1509_7408} {RNA1509_2978, RNA1509_56923, RNA1509_7408, RNA815_1107}
10. MligTC455_44236 8742 182.13 Mlig455_003084, Mlig455_062811

Neo: -

Age: -

RSPH3 1.765 - 0.805 - - - 0.960

Mlig455_003084 {REF} {Length: 2211} {Pfam: Radial spoke protein 3 [PF06098.13, score=416.8]} {Human: ENSG00000130363, RSPH3, radial spoke head 3 homolog, [RH, Score=379, Expect=7e-129]} {Mouse: ENSMUSG00000023806, Rsph3b, radial spoke 3B homolog (Chlamydomonas), [RH, Score=319, Expect=7e-104]; ENSMUSG00000073471, Rsph3a, radial spoke 3A homolog (Chlamydomonas), [RH, Score=318, Expect=5e-104]} {Dmel: FBgn0052392, CG32392, [RH, Score=187, Expect=1e-54]} {Smed: dd_Smed_v6_2287_0_1, dd_Smed_v6_2287_0_1, [RH, Score=454, Expect=9e-159]} {RNA1509_928} {RNA1310_13874} {RNA815_5098}

Mlig455_062811 {REF} {Length: 2209} {Pfam: Radial spoke protein 3 [PF06098.13, score=416.8]} {Human: ENSG00000130363, RSPH3, radial spoke head 3 homolog, [RH, Score=379, Expect=7e-129]} {Mouse: ENSMUSG00000023806, Rsph3b, radial spoke 3B homolog (Chlamydomonas), [RH, Score=319, Expect=7e-104]; ENSMUSG00000073471, Rsph3a, radial spoke 3A homolog (Chlamydomonas), [RH, Score=318, Expect=5e-104]} {Dmel: FBgn0052392, CG32392, [RH, Score=187, Expect=1e-54]} {Smed: dd_Smed_v6_2287_0_1, dd_Smed_v6_2287_0_1, [RH, Score=454, Expect=9e-159]} {RNA1509_928} {RNA1310_13874, RNA1509_928} {RNA1509_928, RNA815_5098}
11. MligTC455_32424 611 12.73 Mlig455_031894, Mlig455_061292, Mlig455_064662

Neo: -

Age: -

1.759 - - 0.958 - - 0.801

Mlig455_031894 {REF} {Length: 1087} {RNA1509_52975} {RNA1310_17621}

Mlig455_061292 {REF} {Length: 179} {NoTransDecoderORF} {RNA1509_52975} {RNA1310_115556}

Mlig455_064662 {REF} {Length: 1953} {RNA1509_52975} {RNA1310_17621} {RNA815_50584}
12. MligTC455_21430 3293 68.61 Mlig455_035694, Mlig455_035788

Neo: -

Age: -

ACSS3 1.751 - 0.800 0.951 - - -

Mlig455_035694 {REF} {Length: 3161} {TRANSSPLICED} {Pfam: AMP-binding enzyme [PF00501.30, score=251.3]; Acetyl-coenzyme A synthetase N-terminus [PF16177.7, score=76.4]; AMP-binding enzyme C-terminal domain [PF13193.8, score=57.4]} {Human: ENSG00000111058, ACSS3, acyl-CoA synthetase short chain family member 3, [RH, Score=716, Expect=0.0]} {Mouse: ENSMUSG00000035948, Acss3, acyl-CoA synthetase short-chain family member 3, [RH, Score=722, Expect=0.0]} {Dmel: FBgn0039184, CG6432, [RH, Score=647, Expect=0.0]} {Celegans: WBGene00007969, acs-19, Acetyl-coenzyme A synthetase, [Score=304, Expect=4e-94]} {Smed: dd_Smed_v6_2832_0_1, dd_Smed_v6_2832_0_1, [RH, Score=758, Expect=0.0]} {RNA1509_2449} {RNA1310_4900.1, RNA1509_2449} {RNA1509_2449, RNA815_4055}

Mlig455_035788 {REF} {Length: 3175} {TRANSSPLICED} {Pfam: AMP-binding enzyme [PF00501.30, score=251.3]; Acetyl-coenzyme A synthetase N-terminus [PF16177.7, score=76.4]; AMP-binding enzyme C-terminal domain [PF13193.8, score=57.3]} {Human: ENSG00000111058, ACSS3, acyl-CoA synthetase short chain family member 3, [RH, Score=715, Expect=0.0]} {Mouse: ENSMUSG00000035948, Acss3, acyl-CoA synthetase short-chain family member 3, [RH, Score=721, Expect=0.0]} {Dmel: FBgn0039184, CG6432, [RH, Score=646, Expect=0.0]} {Celegans: WBGene00007969, acs-19, Acetyl-coenzyme A synthetase, [Score=305, Expect=2e-94]} {Smed: dd_Smed_v6_2832_0_1, dd_Smed_v6_2832_0_1, [RH, Score=758, Expect=0.0]} {RNA1509_2449, RNA1509_34585, RNA1509_56232} {RNA1310_4900.1, RNA1509_34585, RNA1509_56232} {RNA1509_34585, RNA1509_56232, RNA815_4055}
13. MligTC455_36111 458 9.53 Mlig455_043348

Neo: -

Age: logFC(26M/2M)=-0.240

CCDC170 1.748 - 0.785 - - - 0.963 Mlig455_043348 {REF} {Length: 3633} {Pfam: Protein of unknown function (DUF3450) [PF11932.10, score=30.4]} {Human: ENSG00000120262, CCDC170, coiled-coil domain containing 170, [Score=136, Expect=9e-33]} {Mouse: ENSMUSG00000019767, Ccdc170, coiled-coil domain containing 170, [Score=150, Expect=2e-37]} {Dmel: FBgn0263079, CG43338, [Score=84.3, Expect=2e-16]} {Smed: dd_Smed_v6_7066_0_1, dd_Smed_v6_7066_0_1, [Score=192, Expect=7e-52]} {RNA1509_13555, RNA1509_26608, RNA1509_28561, RNA1509_45523, RNA1509_60067} {RNA1310_10671.1, RNA1509_13555, RNA1509_26608, RNA1509_28561, RNA1509_45523, RNA1509_60067} {RNA1509_13555, RNA1509_26608, RNA1509_28561, RNA1509_45523, RNA1509_60067, RNA815_3132}
14. MligTC455_10428 1232 25.66 Mlig455_031930, Mlig455_032667

Neo: -

Age: logFC(26M/2M)=-0.438

WDR66 1.733 - - - 0.779 - 0.954

Mlig455_031930 {REF} {Length: 4976} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=69.8]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=25.4]; Rab3 GTPase-activating protein regulatory subunit N-terminus [PF14655.8, score=18.5]} {Human: ENSG00000158023, WDR66, WD repeat domain 66, [Score=492, Expect=1e-158]} {Mouse: ENSMUSG00000029442, Wdr66, WD repeat domain 66, [Score=487, Expect=4e-153]} {Celegans: WBGene00006820, unc-89, Muscle M-line assembly protein unc-89, [Score=58.5, Expect=3e-08]} {Smed: dd_Smed_v6_11127_0_2, dd_Smed_v6_11127_0_2, [Score=655, Expect=0.0]} {RNA1509_16171} {RNA1310_3690} {RNA815_918.1}

Mlig455_032667 {REF} {Length: 4277} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=81.1]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=24.8]} {Human: ENSG00000158023, WDR66, WD repeat domain 66, [RH, Score=779, Expect=0.0]} {Mouse: ENSMUSG00000029442, Wdr66, WD repeat domain 66, [RH, Score=771, Expect=0.0]} {Dmel: FBgn0039867, CstF50, Cleavage stimulation factor 50 kD subunit, [Score=51.2, Expect=5e-06]} {Celegans: WBGene00006820, unc-89, Muscle M-line assembly protein unc-89, [Score=68.9, Expect=2e-11]} {Smed: dd_Smed_v6_11127_0_2, dd_Smed_v6_11127_0_2, [RH, Score=939, Expect=0.0]} {RNA1509_3046} {RNA1310_3690} {RNA815_918.1}
15. MligTC455_41649 620 12.92 Mlig455_020504

Neo: -

Age: -

Region-enriched R2: 2.043/0.04322

ARMC9 1.724 - 0.769 - - - 0.955 Mlig455_020504 {REF} {Length: 2988} {TRANSSPLICED} {Human: ENSG00000135931, ARMC9, armadillo repeat containing 9, [RH, Score=536, Expect=0.0]} {Mouse: ENSMUSG00000062590, Armc9, armadillo repeat containing 9, [RH, Score=530, Expect=4e-177]} {Smed: dd_Smed_v6_10926_0_1, dd_Smed_v6_10926_0_1, [RH, Score=499, Expect=6e-166]} {RNA1509_9388} {RNA1310_10290, RNA1509_9388} {RNA1509_9388, RNA815_4141}
16. MligTC455_35942 1134 23.63 Mlig455_048067

Neo: -

Age: logFC(26M/2M)=-0.435

DCDC2C 1.712 - 0.762 - - - 0.950 Mlig455_048067 {REF} {Length: 3258} {Pfam: Doublecortin [PF03607.19, score=93.4]} {Human: ENSG00000214866, DCDC2C, doublecortin domain containing 2C, [RH, Score=100, Expect=7e-23]; ENSG00000146038, DCDC2, doublecortin domain containing 2, [RH, Score=100, Expect=3e-22]} {Mouse: ENSMUSG00000035910, Dcdc2a, doublecortin domain containing 2a, [RH, Score=105, Expect=2e-24]} {Celegans: WBGene00007374, C06C3.3, [RH, Score=52.4, Expect=4e-07]} {Smed: dd_Smed_v6_20159_0_1, dd_Smed_v6_20159_0_1, [RH, Score=187, Expect=9e-55]} {RNA1509_40680} {RNA1310_11042} {RNA815_6202}
17. MligTC455_17865 2593 54.02 Mlig455_034927

Neo: -

Age: Down-Up-Up

FANK1 1.711 - 0.759 - - - 0.952 Mlig455_034927 {REF} {Length: 1596} {TRANSSPLICED} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=107.8]; Ankyrin repeats (3 copies) [PF12796.9, score=102.8]; Ankyrin repeats (many copies) [PF13857.8, score=85.2]; Ankyrin repeat [PF00023.32, score=73.5]; Ankyrin repeat [PF13606.8, score=64.1]} {Human: ENSG00000203780, FANK1, fibronectin type III and ankyrin repeat domains 1, [Score=174, Expect=7e-51]} {Mouse: ENSMUSG00000053111, Fank1, fibronectin type 3 and ankyrin repeat domains 1, [RH, Score=174, Expect=7e-51]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=93.2, Expect=3e-20]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=94.7, Expect=8e-21]} {Smed: dd_Smed_v6_7571_0_2, dd_Smed_v6_7571_0_2, [RH, Score=253, Expect=9e-82]} {RNA1509_6757} {RNA1310_18708, RNA1509_6757} {RNA1509_6757, RNA815_8175}
18. MligTC455_47160 747 15.56 Mlig455_021750

Neo: -

Age: logFC(26M/2M)=-0.246

FAM184A 1.702 - 0.743 - - - 0.959 Mlig455_021750 {REF} {Length: 3705} {Pfam: Family with sequence similarity 184, A and B [PF15665.7, score=130.1]} {Human: ENSG00000111879, FAM184A, family with sequence similarity 184 member A, [RH, Score=340, Expect=5e-99]} {Mouse: ENSMUSG00000019856, Fam184a, family with sequence similarity 184, member A, [RH, Score=308, Expect=7e-88]} {Celegans: WBGene00001328, epi-1, Laminin-like protein epi-1, [Score=60.8, Expect=5e-09]} {Smed: dd_Smed_v6_16975_0_1, dd_Smed_v6_16975_0_1, [RH, Score=264, Expect=3e-73]} {RNA1509_5806} {RNA1310_3258.1, RNA1509_5806} {RNA1509_5806, RNA815_936}
19. MligTC455_32423 283 5.9 Mlig455_055060

Neo: Irradiation

Age: Up-Down-Down

1.688 - - 0.954 - - 0.734 Mlig455_055060 {REF} {Length: 2866} {RNA1509_52975} {RNA1310_17621, RNA1509_52975} {RNA1509_52975, RNA815_10158}
20. MligTC455_43972 1061 22.11 Mlig455_047704

Neo: -

Age: -

1.661 - 0.705 - - - 0.956 Mlig455_047704 {REF} {Length: 2155} {TRANSSPLICED} {RNA1509_7618} {RNA1310_9007} {RNA815_27926.1}
21. MligTC455_49730 949 19.77 Mlig455_018448

Neo: -

Age: logFC(26M/2M)=-0.195

Region-enriched R2: 1.188/0.02467

TNKS 0.975 - - - - - 0.975 Mlig455_018448 {REF} {Length: 3480} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=75.2]; Ion transport protein [PF00520.33, score=64.2]; Ankyrin repeats (many copies) [PF13857.8, score=59.3]; Ankyrin repeat [PF13606.8, score=53.2]; Ankyrin repeat [PF00023.32, score=51.3]; Ankyrin repeats (many copies) [PF13637.8, score=51.3]; Polycystin cation channel [PF08016.14, score=19.7]} {Human: ENSG00000173273, TNKS, tankyrase, [Score=89.4, Expect=2e-17]; ENSG00000285372, AC270292.3, tankyrase, [Score=89.0, Expect=3e-17]; ENSG00000135299, ANKRD6, ankyrin repeat domain 6, [Score=87.4, Expect=5e-18]} {Mouse: ENSMUSG00000031529, Tnks, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, [Score=89.0, Expect=2e-17]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=83.6, Expect=6e-16]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=90.9, Expect=2e-18]} {Smed: dd_Smed_v6_10764_0_3, dd_Smed_v6_10764_0_3, [Score=80.9, Expect=1e-15]} {RNA1509_23119, RNA1509_31186, RNA1509_44376} {RNA1310_4706, RNA1509_23119, RNA1509_31186, RNA1509_44376} {RNA1509_23119, RNA1509_31186, RNA1509_44376, RNA815_1228}
22. MligTC455_44709 1473 30.68 Mlig455_044126

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.323

Region-enriched R2: 1.087/0.01396

CFAP20 0.972 - - - - - 0.972 Mlig455_044126 {REF} {Length: 1458} {Pfam: Protein of unknown function (DUF667) [PF05018.15, score=306.8]} {Human: ENSG00000070761, CFAP20, cilia and flagella associated protein 20, [RH, Score=360, Expect=1e-128]} {Mouse: ENSMUSG00000031796, Cfap20, cilia and flagella associated protein 20, [RH, Score=363, Expect=9e-130]} {Dmel: FBgn0032248, Bug22, Basal body up regulated gene 22, [RH, Score=355, Expect=1e-126]} {Celegans: WBGene00008288, C54C6.6, Cilia- and flagella-associated protein 20, [RH, Score=333, Expect=4e-118]} {Smed: dd_Smed_v6_4843_0_1, dd_Smed_v6_4843_0_1, [RH, Score=363, Expect=2e-130]} {RNA1509_27107, RNA1509_35008, RNA1509_5810} {RNA1310_18346.2, RNA1509_27107, RNA1509_35008} {RNA1509_27107, RNA1509_35008, RNA815_7118.1}
23. MligTC455_25435 1465 30.52 Mlig455_029258, Mlig455_035644, Mlig455_035745

Neo: -

Age: Down-Up-Down

0.967 - - - - - 0.967

Mlig455_029258 {REF} {Length: 2882} {Smed: dd_Smed_v6_10509_0_1, dd_Smed_v6_10509_0_1, [RH, Score=269, Expect=5e-82]} {RNA1509_7251} {RNA1310_6183.1} {RNA815_4378.1}

Mlig455_035644 {REF} {Length: 2993} {Smed: dd_Smed_v6_10509_0_1, dd_Smed_v6_10509_0_1, [RH, Score=265, Expect=2e-80]} {RNA1509_50619, RNA1509_7251} {RNA1310_6183.1, RNA1509_50619, RNA1509_7251} {RNA1509_50619, RNA1509_7251, RNA815_4378.1}

Mlig455_035745 {REF} {Length: 3080} {Smed: dd_Smed_v6_10509_0_1, dd_Smed_v6_10509_0_1, [RH, Score=266, Expect=8e-81]} {RNA1509_50619} {RNA1310_6183.1} {RNA815_4378.1}
24. MligTC455_50996 449 9.36 Mlig455_002019

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=-0.319

Region-enriched R2: 1.520/0.04245

TRIM71 0.967 - - - - - 0.967 Mlig455_002019 {REF} {Length: 2281} {Pfam: NHL repeat [PF01436.23, score=74.6]} {Human: ENSG00000206557, TRIM71, tripartite motif containing 71, [Score=79.3, Expect=3e-15]; ENSG00000109654, TRIM2, tripartite motif containing 2, [Score=76.3, Expect=3e-14]} {Mouse: ENSMUSG00000079259, Trim71, tripartite motif-containing 71, [Score=79.7, Expect=2e-15]; ENSMUSG00000027993, Trim2, tripartite motif-containing 2, [Score=76.3, Expect=2e-14]} {Dmel: FBgn0265356, tn, thin, [Score=94.0, Expect=3e-20]} {Celegans: WBGene00003026, lin-41, [Score=80.5, Expect=5e-16]} {Smed: dd_Smed_v6_13659_0_1, dd_Smed_v6_13659_0_1, [RH, Score=102, Expect=2e-24]} {RNA1509_17378} {RNA1310_19512.1, RNA1509_17378} {RNA1509_17378, RNA815_7968}
25. MligTC455_17351 766 15.96 Mlig455_009441

Neo: -

Age: -

Region-enriched R2: 2.466/0.00083
Region-enriched R4: 1.757/0.02374

USH2A 0.964 - - - - - 0.964 Mlig455_009441 {REF} {Length: 3984} {Pfam: Fibronectin type III domain [PF00041.23, score=76.6]; Neuron-derived neurotrophic factor [PF10179.11, score=24.4]; Fibronectin type III domain [PF16893.7, score=23.7]; Purple acid Phosphatase, N-terminal domain [PF16656.7, score=22.6]; HEAT repeats [PF13646.8, score=22.2]} {Human: ENSG00000042781, USH2A, usherin, [Score=94.7, Expect=7e-19]} {Mouse: ENSMUSG00000026609, Ush2a, usherin, [Score=77.0, Expect=1e-13]} {Dmel: FBgn0259735, CG42389, [Score=59.3, Expect=2e-08]} {Celegans: WBGene00010558, ptp-4, Tyrosine-protein phosphatase 4, [Score=51.2, Expect=4e-06]} {Smed: dd_Smed_v6_15017_0_1, dd_Smed_v6_15017_0_1, [RH, Score=411, Expect=8e-129]} {RNA1509_13146, RNA1509_35474, RNA1509_50831} {RNA1310_2905.1, RNA1509_13146, RNA1509_35474, RNA1509_50831} {RNA1509_13146, RNA1509_35474, RNA1509_50831, RNA815_2595.1}
26. MligTC455_21382 1874 39.04 Mlig455_004691, Mlig455_004766, Mlig455_004851

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.455

Region-enriched R2: 1.848/0.00119

CEP164 0.962 - - - - - 0.962

Mlig455_004691 {REF} {Length: 3647} {Pfam: WW domain [PF00397.28, score=27.1]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=119, Expect=2e-27]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=118, Expect=2e-27]} {Dmel: FBgn0030716, CG9170, [Score=87.0, Expect=2e-17]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=115, Expect=7e-27]} {RNA1509_14489, RNA1509_33857, RNA1509_43099} {RNA1310_8537, RNA1509_14489, RNA1509_33857, RNA1509_43099} {RNA1509_14489, RNA1509_33857, RNA1509_43099, RNA815_4051}

Mlig455_004766 {REF} {Length: 3501} {Pfam: WW domain [PF00397.28, score=27.8]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=118, Expect=4e-27]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=118, Expect=3e-27]} {Dmel: FBgn0030716, CG9170, [Score=87.8, Expect=9e-18]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=116, Expect=2e-27]} {RNA1509_14489, RNA1509_41953} {RNA1310_8872, RNA1509_41953} {RNA1509_41953, RNA815_4051}

Mlig455_004851 {REF} {Length: 2227} {Pfam: WW domain [PF00397.28, score=27.7]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=118, Expect=4e-27]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=117, Expect=5e-27]} {Dmel: FBgn0030716, CG9170, [Score=86.3, Expect=3e-17]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=116, Expect=3e-27]} {RNA1509_14489} {RNA1310_8872} {RNA815_4051}
27. MligTC455_47611 558 11.62 Mlig455_032020

Neo: -

Age: -

BBOX1 0.961 - - 0.961 - - - Mlig455_032020 {REF} {Length: 1876} {TRANSSPLICED} {Pfam: Taurine catabolism dioxygenase TauD, TfdA family [PF02668.18, score=143.1]; Gamma-butyrobetaine hydroxylase-like, N-terminal [PF06155.14, score=40.5]} {Human: ENSG00000129151, BBOX1, gamma-butyrobetaine hydroxylase 1, [Score=223, Expect=3e-68]} {Mouse: ENSMUSG00000041660, Bbox1, butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase), [Score=230, Expect=4e-71]} {Dmel: FBgn0030575, CG5321, [Score=235, Expect=9e-73]} {Celegans: WBGene00001522, gbh-1, Probable gamma-butyrobetaine dioxygenase, [Score=156, Expect=7e-43]} {Smed: dd_Smed_v6_42907_0_1, dd_Smed_v6_42907_0_1, [Score=65.9, Expect=6e-12]} {RNA1509_19035} {RNA1310_2841} {RNA815_6735}
28. MligTC455_39735 601 12.52 Mlig455_014637

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.439/0.03156

0.96 - - - - - 0.960 Mlig455_014637 {REF} {Length: 3559} {Pfam: Domain of unknown function (DUF4537) [PF15057.8, score=61.8]; von Willebrand factor type A domain [PF13768.8, score=20.3]} {Smed: dd_Smed_v6_10837_0_1, dd_Smed_v6_10837_0_1, [RH, Score=94.7, Expect=1e-19]} {RNA1509_28750, RNA1509_45023} {RNA1310_4730, RNA1509_28750, RNA1509_45023} {RNA1509_28750, RNA1509_45023, RNA815_8808}
29. MligTC455_49287 1118 23.29 Mlig455_057092

Neo: -

Age: -

0.96 - - - - - 0.960 Mlig455_057092 {REF} {Length: 2993} {Pfam: Domain of unknown function (DUF3827) [PF12877.9, score=61.8]} {Smed: dd_Smed_v6_14943_0_1, dd_Smed_v6_14943_0_1, [RH, Score=119, Expect=2e-28]} {RNA1509_21621, RNA1509_51764, RNA1509_54889} {RNA1310_10191, RNA1509_21621, RNA1509_51764, RNA1509_54889} {RNA1509_21621, RNA1509_51764, RNA1509_54889, RNA815_2779.1}
30. MligTC455_45196 415 8.66 Mlig455_012327

Neo: -

Age: logFC(26M/2M)=-0.373

INVS 0.958 - - - - - 0.958 Mlig455_012327 {REF} {Length: 3620} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=130.7]; Ankyrin repeats (many copies) [PF13637.8, score=103.5]; Ankyrin repeats (many copies) [PF13857.8, score=90.3]; Ankyrin repeat [PF13606.8, score=74.3]; Ankyrin repeat [PF00023.32, score=60.1]} {Human: ENSG00000119509, INVS, inversin, [Score=114, Expect=3e-25]; ENSG00000065413, ANKRD44, ankyrin repeat domain 44, [Score=111, Expect=9e-25]; ENSG00000139645, ANKRD52, ankyrin repeat domain 52, [Score=110, Expect=6e-24]} {Mouse: ENSMUSG00000014498, Ankrd52, ankyrin repeat domain 52, [Score=107, Expect=3e-23]; ENSMUSG00000052331, Ankrd44, ankyrin repeat domain 44, [Score=107, Expect=2e-23]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=104, Expect=4e-22]; ENSMUSG00000014496, Ankrd28, ankyrin repeat domain 28, [Score=103, Expect=5e-22]; ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=102, Expect=2e-21]} {Dmel: FBgn0260487, CG42534, [Score=112, Expect=6e-25]} {Celegans: WBGene00021304, nphp-2, NePHronoPhthisis (Human kidney disease) homolog, [Score=99.0, Expect=5e-21]} {Smed: dd_Smed_v6_16174_0_1, dd_Smed_v6_16174_0_1, [Score=115, Expect=3e-26]} {RNA1509_13535, RNA1509_36786} {RNA1310_5307.1, RNA1509_36786} {RNA1509_36786, RNA815_942}
31. MligTC455_46196 2159 44.98 Mlig455_047133, Mlig455_047135, Mlig455_068480

Neo: -

Age: -

0.958 - - - 0.958 - -

Mlig455_047133 {REF} {Length: 2777} {Pfam: WSC domain [PF01822.21, score=48.2]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=52.4, Expect=8e-07]} {RNA1509_33020} {RNA1310_2214} {RNA815_4028.1}

Mlig455_047135 {REF} {Length: 2240} {RNA1509_33020} {RNA1310_2349, RNA1509_33020} {RNA1509_33020, RNA815_4028.1}

Mlig455_068480 {REF} {Length: 5647} {Dmel: FBgn0264693, ens, ensconsin, [Score=65.1, Expect=2e-10]} {Smed: dd_Smed_v6_5361_0_1, dd_Smed_v6_5361_0_1, [Score=59.3, Expect=1e-08]} {RNA1509_30837} {RNA1310_2110.2} {RNA815_4028.1}
32. MligTC455_19642 697 14.51 Mlig455_008581

Neo: -

Age: -

CDKAL1 0.957 - - 0.957 - - - Mlig455_008581 {REF} {Length: 2592} {TRANSSPLICED} {Pfam: Uncharacterized protein family UPF0004 [PF00919.22, score=70.7]; Radical SAM superfamily [PF04055.23, score=52.5]; TRAM domain [PF01938.22, score=22.3]} {Human: ENSG00000145996, CDKAL1, CDK5 regulatory subunit associated protein 1 like 1, [RH, Score=585, Expect=0.0]} {Mouse: ENSMUSG00000006191, Cdkal1, CDK5 regulatory subunit associated protein 1-like 1, [RH, Score=574, Expect=0.0]} {Dmel: FBgn0034214, CG6550, [RH, Score=594, Expect=0.0]} {Celegans: WBGene00022363, Y92H12BL.1, Threonylcarbamoyladenosine tRNA methylthiotransferase, [RH, Score=389, Expect=5e-131]} {Smed: dd_Smed_v6_2358_0_1, dd_Smed_v6_2358_0_1, [RH, Score=558, Expect=0.0]} {RNA1509_38379, RNA1509_55471, RNA1509_8176} {RNA1310_6972.2, RNA1509_38379, RNA1509_55471, RNA1509_8176} {RNA1509_38379, RNA1509_55471, RNA1509_8176, RNA815_7659}
33. MligTC455_41538 1908 39.76 Mlig455_010187, Mlig455_058608, Mlig455_058684

Neo: -

Age: -

CCDC170 0.955 - - - - - 0.955

Mlig455_010187 {REF} {Length: 3945} {Human: ENSG00000120262, CCDC170, coiled-coil domain containing 170, [RH, Score=283, Expect=1e-83]} {Mouse: ENSMUSG00000019767, Ccdc170, coiled-coil domain containing 170, [RH, Score=273, Expect=3e-80]} {Dmel: FBgn0263079, CG43338, [RH, Score=117, Expect=9e-27]} {Smed: dd_Smed_v6_10140_0_2, dd_Smed_v6_10140_0_2, [RH, Score=296, Expect=3e-88]} {RNA1509_3115} {RNA1310_2598} {RNA815_746}

Mlig455_058608 {REF} {Length: 3920} {Human: ENSG00000120262, CCDC170, coiled-coil domain containing 170, [Score=209, Expect=8e-58]} {Mouse: ENSMUSG00000019767, Ccdc170, coiled-coil domain containing 170, [Score=224, Expect=2e-63]} {Dmel: FBgn0263079, CG43338, [Score=95.5, Expect=6e-20]} {Smed: dd_Smed_v6_7992_0_1, dd_Smed_v6_7992_0_1, [Score=211, Expect=1e-58]} {RNA1509_3115} {RNA1310_2598} {RNA815_746}

Mlig455_058684 {REF} {Length: 3883} {Human: ENSG00000120262, CCDC170, coiled-coil domain containing 170, [RH, Score=272, Expect=1e-79]} {Mouse: ENSMUSG00000019767, Ccdc170, coiled-coil domain containing 170, [Score=257, Expect=3e-74]} {Dmel: FBgn0263079, CG43338, [RH, Score=108, Expect=8e-24]} {Smed: dd_Smed_v6_7066_0_1, dd_Smed_v6_7066_0_1, [Score=272, Expect=6e-80]} {RNA1509_3115} {RNA1310_2598} {RNA815_746}
34. MligTC455_46255 2218 46.21 Mlig455_024833

Neo: -

Age: logFC(26M/2M)=-0.329

CASC1 0.954 - - - - - 0.954 Mlig455_024833 {REF} {Length: 2822} {Pfam: Cancer susceptibility candidate 1 N-terminus [PF15927.7, score=170.2]; Cancer susceptibility candidate 1 C-terminal [PF12366.10, score=30.7]} {Human: ENSG00000118307, CASC1, cancer susceptibility 1, [RH, Score=319, Expect=1e-97]} {Mouse: ENSMUSG00000043541, Casc1, cancer susceptibility candidate 1, [RH, Score=293, Expect=5e-88]} {Dmel: FBgn0030889, CG15373, [RH, Score=82.4, Expect=8e-16]} {Smed: dd_Smed_v6_11291_0_1, dd_Smed_v6_11291_0_1, [RH, Score=521, Expect=7e-175]} {RNA1509_1842} {RNA1310_6962.1} {RNA815_2139}
35. MligTC455_48259 676 14.08 Mlig455_020900

Neo: -

Age: -

CALM2 0.953 - - - - - 0.953 Mlig455_020900 {REF} {Length: 1620} {Pfam: EF hand [PF00036.34, score=97.7]; EF-hand domain pair [PF13499.8, score=83.8]; EF hand [PF13202.8, score=77.0]; EF-hand domain [PF13405.8, score=71.6]; EF-hand domain pair [PF13833.8, score=70.2]; EF-hand domain [PF14658.8, score=31.0]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=25.2]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=23.5]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=104, Expect=2e-27]; ENSG00000198668, CALM1, calmodulin 1, [Score=103, Expect=9e-28]; ENSG00000160014, CALM3, calmodulin 3, [Score=103, Expect=1e-27]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=105, Expect=8e-28]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=103, Expect=7e-28]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=103, Expect=7e-28]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=100, Expect=2e-26]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=103, Expect=1e-27]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=103, Expect=8e-28]} {Smed: dd_Smed_v6_11942_0_1, dd_Smed_v6_11942_0_1, [Score=104, Expect=3e-28]} {RNA1509_42541, RNA1509_8417} {RNA1310_18928.1, RNA1509_42541, RNA1509_8417} {RNA1509_42541, RNA1509_8417, RNA815_13201}
36. MligTC455_52049 2902 60.46 Mlig455_017142, Mlig455_048103

Neo: -

Age: logFC(26M/2M)=-0.510

Region-specific R2: 1.711

Region-enriched R2: 1.034/0.01842

0.952 - - - - - 0.952

Mlig455_017142 {REF} {Length: 2340} {Pfam: D-arabinono-1,4-lactone oxidase [PF04030.16, score=41.0]; FAD binding domain [PF01565.25, score=28.9]} {Mouse: ENSMUSG00000034450, Gulo, gulonolactone (L-) oxidase, [Score=52.8, Expect=8e-07]} {Smed: dd_Smed_v6_10292_0_1, dd_Smed_v6_10292_0_1, [RH, Score=130, Expect=3e-32]} {RNA1509_2896} {RNA1310_10814} {RNA815_3783}

Mlig455_048103 {REF} {Length: 2340} {Pfam: D-arabinono-1,4-lactone oxidase [PF04030.16, score=41.0]; FAD binding domain [PF01565.25, score=28.9]} {Mouse: ENSMUSG00000034450, Gulo, gulonolactone (L-) oxidase, [Score=52.8, Expect=8e-07]} {Smed: dd_Smed_v6_10292_0_1, dd_Smed_v6_10292_0_1, [RH, Score=130, Expect=3e-32]} {RNA1509_2896, RNA1509_45480} {RNA1310_10814, RNA1509_2896, RNA1509_45480} {RNA1509_2896, RNA1509_45480, RNA815_3783}
37. MligTC455_51696 624 12.99 Mlig455_011356

Neo: -

Age: -

FAM47E 0.95 - - - - - 0.950 Mlig455_011356 {REF} {Length: 2028} {Pfam: FAM47 family [PF14642.8, score=51.3]} {Human: ENSG00000189157, FAM47E, family with sequence similarity 47 member E, [RH, Score=138, Expect=9e-36]} {Mouse: ENSMUSG00000078315, Fam47c, family with sequence similarity 47, member C, [RH, Score=119, Expect=6e-29]} {Smed: dd_Smed_v6_10346_0_1, dd_Smed_v6_10346_0_1, [RH, Score=293, Expect=6e-95]} {RNA1509_41096, RNA1509_54260, RNA1509_8031} {RNA1310_12665, RNA1509_41096, RNA1509_54260} {RNA1509_41096, RNA1509_54260, RNA815_4489.1}

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