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Results for MligTC455_45969

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_45969 1220 25.42 Mlig455_045083

Neo: -

Age: -

 Mlig455_045083 {REF} {Length: 2063} {TRANSSPLICED} {RNA1509_16069, RNA1509_41818, RNA1509_49053, RNA1509_56846} {RNA1310_17143, RNA1509_41818, RNA1509_49053, RNA1509_56846} {RNA1509_41818, RNA1509_49053, RNA1509_56846, RNA815_14588}

Cumulative graph for MligTC455_45969

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.19 4.851 0.81436 1.00000
RegionR2 0.347 4.851 0.31497 0.70615
RegionR3 -0.091 4.851 0.74562 1.00000
RegionR4 -0.221 4.851 0.51438 0.84009
RegionR5 0.067 4.851 0.79316 1.00000
RegionR6 -0.367 4.851 0.21939 0.79916
RegionR7 -0.019 4.851 0.95943 1.00000
RegionR8 0.474 4.851 0.28172 0.90822

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.969 4.851 0.44521 1.00000
RegenerationR2 0.411 4.851 0.13246 0.55872
RegenerationR3 0.223 4.851 0.48612 0.85333
RegenerationR4 0.048 4.851 0.88746 1.00000
RegenerationR5 -0.039 4.851 0.89332 1.00000
RegenerationR6 -0.116 4.851 0.73648 0.94547
RegenerationBL -0.638 4.851 0.12514 0.42004
RegenerationTP -0.307 4.851 0.46037 0.87419


Genes with expression patterns similar to MligTC455_45969

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_45969 1220 25.42 Mlig455_045083

Neo: -

Age: -

 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_045083 {REF} {Length: 2063} {TRANSSPLICED} {RNA1509_16069, RNA1509_41818, RNA1509_49053, RNA1509_56846} {RNA1310_17143, RNA1509_41818, RNA1509_49053, RNA1509_56846} {RNA1509_41818, RNA1509_49053, RNA1509_56846, RNA815_14588}
2. MligTC455_33842 492 10.26 Mlig455_004899

Neo: -

Age: -

Region-enriched R2: 2.178/0.01972

 CDKL1 1.878 - - - 0.953 0.925 - Mlig455_004899 {REF} {Length: 2500} {Pfam: Protein kinase domain [PF00069.27, score=247.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=116.6]; Haspin like kinase domain [PF12330.10, score=18.7]; ABC1 atypical kinase-like domain [PF03109.18, score=18.6]} {Human: ENSG00000100490, CDKL1, cyclin dependent kinase like 1, [RH, Score=429, Expect=3e-150]; ENSG00000205111, CDKL4, cyclin dependent kinase like 4, [RH, Score=422, Expect=2e-148]} {Mouse: ENSMUSG00000020990, Cdkl1, cyclin-dependent kinase-like 1 (CDC2-related kinase), [RH, Score=432, Expect=7e-152]; ENSMUSG00000033966, Cdkl4, cyclin-dependent kinase-like 4, [RH, Score=423, Expect=3e-148]} {Dmel: FBgn0031730, CG7236, [RH, Score=381, Expect=6e-131]} {Celegans: WBGene00012779, cdkl-1, Cyclin-Dependent Kinase-Like, [RH, Score=396, Expect=4e-136]} {Smed: dd_Smed_v6_9353_0_1, dd_Smed_v6_9353_0_1, [RH, Score=481, Expect=5e-171]} {RNA1509_19679} {RNA1310_6686.1} {RNA815_5397}
3. MligTC455_35664 1772 36.91 Mlig455_020393, Mlig455_028392, Mlig455_058437

Neo: -

Age: logFC(26M/2M)=-0.217

Region-enriched R4: 1.033/0.04115

 CLHC1 1.833 - - - 0.878 0.955 -

Mlig455_020393 {REF} {Length: 1999} {Pfam: Translin-associated factor X-interacting N-terminus [PF15739.7, score=57.3]; Clathrin-H-link [PF13838.8, score=34.4]} {Human: ENSG00000162994, CLHC1, clathrin heavy chain linker domain containing 1, [RH, Score=155, Expect=8e-40]} {Mouse: ENSMUSG00000020461, Clhc1, clathrin heavy chain linker domain containing 1, [RH, Score=160, Expect=8e-42]} {Celegans: WBGene00011867, chc-1, Probable clathrin heavy chain 1, [Score=51.2, Expect=2e-06]} {Smed: dd_Smed_v6_9605_0_1, dd_Smed_v6_9605_0_1, [RH, Score=145, Expect=4e-37]} {RNA1509_8364} {RNA1310_5794.1} {RNA815_1706}

Mlig455_028392 {REF} {Length: 1994} {TRANSSPLICED} {Pfam: Clathrin-H-link [PF13838.8, score=35.7]} {Human: ENSG00000162994, CLHC1, clathrin heavy chain linker domain containing 1, [Score=110, Expect=4e-25]} {Mouse: ENSMUSG00000047126, Cltc, clathrin, heavy polypeptide (Hc), [Score=54.7, Expect=3e-07]} {Celegans: WBGene00011867, chc-1, Probable clathrin heavy chain 1, [Score=50.4, Expect=3e-06]} {Smed: dd_Smed_v6_9605_0_1, dd_Smed_v6_9605_0_1, [Score=114, Expect=1e-26]} {RNA1509_8364} {RNA1310_5794.1} {RNA815_1706}

Mlig455_058437 {REF} {Length: 2088} {Pfam: Translin-associated factor X-interacting N-terminus [PF15739.7, score=57.4]; Clathrin-H-link [PF13838.8, score=34.4]} {Human: ENSG00000162994, CLHC1, clathrin heavy chain linker domain containing 1, [Score=153, Expect=3e-39]} {Mouse: ENSMUSG00000020461, Clhc1, clathrin heavy chain linker domain containing 1, [Score=158, Expect=4e-41]} {Celegans: WBGene00011867, chc-1, Probable clathrin heavy chain 1, [Score=50.8, Expect=3e-06]} {Smed: dd_Smed_v6_9605_0_1, dd_Smed_v6_9605_0_1, [Score=144, Expect=9e-37]} {RNA1509_8364} {RNA1310_5794.1} {RNA815_1706}
4. MligTC455_48051 729 15.19 Mlig455_037292, Mlig455_037331

Neo: -

Age: logFC(26M/2M)=-0.645

Region-enriched R2: 2.891/0.00005

 AGBL3 1.822 - - - 0.951 0.871 -

Mlig455_037292 {REF} {Length: 4360} {Pfam: Zinc carboxypeptidase [PF00246.26, score=66.0]; Cytosolic carboxypeptidase N-terminal domain [PF18027.3, score=64.0]} {Human: ENSG00000146856, AGBL3, ATP/GTP binding protein like 3, [Score=547, Expect=1e-176]; ENSG00000165923, AGBL2, ATP/GTP binding protein like 2, [Score=521, Expect=5e-167]; ENSG00000285501, AGBL2, ATP/GTP binding protein like 2, [Score=521, Expect=5e-167]} {Mouse: ENSMUSG00000038836, Agbl3, ATP/GTP binding protein-like 3, [Score=542, Expect=9e-174]; ENSMUSG00000040812, Agbl2, ATP/GTP binding protein-like 2, [Score=528, Expect=5e-170]} {Dmel: FBgn0265726, Nna1, Nna1 carboxypeptidase, [Score=489, Expect=3e-157]} {Celegans: WBGene00018995, ccpp-1, Cytosolic carboxypeptidase 1, [Score=276, Expect=6e-77]} {Smed: dd_Smed_v6_13450_0_1, dd_Smed_v6_13450_0_1, [Score=533, Expect=2e-171]} {RNA1509_25820} {RNA1310_2132.1} {RNA815_1862}

Mlig455_037331 {REF} {Length: 4775} {Pfam: Cytosolic carboxypeptidase N-terminal domain [PF18027.3, score=70.1]; Zinc carboxypeptidase [PF00246.26, score=65.7]} {Human: ENSG00000146856, AGBL3, ATP/GTP binding protein like 3, [RH, Score=575, Expect=0.0]} {Mouse: ENSMUSG00000040812, Agbl2, ATP/GTP binding protein-like 2, [RH, Score=569, Expect=0.0]; ENSMUSG00000038836, Agbl3, ATP/GTP binding protein-like 3, [RH, Score=568, Expect=0.0]} {Dmel: FBgn0265726, Nna1, Nna1 carboxypeptidase, [Score=520, Expect=2e-168]} {Celegans: WBGene00018995, ccpp-1, Cytosolic carboxypeptidase 1, [Score=290, Expect=1e-81]} {Smed: dd_Smed_v6_13450_0_1, dd_Smed_v6_13450_0_1, [RH, Score=604, Expect=0.0]} {RNA1509_25820} {RNA1310_2132.1} {RNA815_1862}
5. MligTC455_32487 595 12.39 Mlig455_017119

Neo: -

Age: logFC(26M/2M)=-0.391

 1.79 - - - 0.951 0.839 - Mlig455_017119 {REF} {Length: 2322} {RNA1509_10657} {RNA1310_11689, RNA1509_10657} {RNA1509_10657, RNA815_5499}
6. MligTC455_45502 324 6.75 Mlig455_057191

Neo: -

Age: -

 USP54 1.762 - - - 0.795 - 0.967 Mlig455_057191 {REF} {Length: 5240} {TRANSSPLICED} {Pfam: Ubiquitin carboxyl-terminal hydrolase [PF00443.31, score=56.2]} {Human: ENSG00000166348, USP54, ubiquitin specific peptidase 54, [RH, Score=280, Expect=7e-79]} {Mouse: ENSMUSG00000034235, Usp54, ubiquitin specific peptidase 54, [RH, Score=279, Expect=7e-79]} {Dmel: FBgn0000542, ec, echinus, [RH, Score=236, Expect=1e-64]} {RNA1509_14635, RNA1509_38398} {RNA1310_8155.1, RNA1509_14635, RNA1509_38398} {RNA1509_14635, RNA1509_38398, RNA815_4435}
7. MligTC455_40285 1881 39.19 Mlig455_057081

Neo: -

Age: logFC(26M/2M)=-0.239

 IQCA1 1.735 - - - 0.778 0.957 - Mlig455_057081 {REF} {Length: 2924} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=56.3]} {Human: ENSG00000132321, IQCA1, IQ motif containing with AAA domain 1, [RH, Score=773, Expect=0.0]} {Mouse: ENSMUSG00000026301, Iqca, IQ motif containing with AAA domain, [Score=736, Expect=0.0]} {Dmel: FBgn0037712, CG16789, [Score=542, Expect=0.0]} {Smed: dd_Smed_v6_9484_0_1, dd_Smed_v6_9484_0_1, [RH, Score=496, Expect=7e-168]} {RNA1509_2357} {RNA1310_6088.1} {RNA815_1468.1}
8. MligTC455_34365 761 15.86 Mlig455_045898

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-1.155

 1.731 - - - - 0.951 0.780 Mlig455_045898 {REF} {Length: 1534} {RNA1509_18388, RNA1509_36026, RNA1509_43852} {RNA1310_33460, RNA1509_18388, RNA1509_36026, RNA1509_43852} {RNA1509_18388, RNA1509_36026, RNA1509_43852, RNA815_35266}
9. MligTC455_43293 2619 54.57 Mlig455_001393

Neo: -

Age: -

Region-specific R2: 1.579

 ANXA7 1.723 - - - 0.770 0.953 - Mlig455_001393 {REF} {Length: 4698} {Pfam: Annexin [PF00191.22, score=268.6]} {Human: ENSG00000138279, ANXA7, annexin A7, [RH, Score=307, Expect=6e-98]} {Mouse: ENSMUSG00000021814, Anxa7, annexin A7, [RH, Score=301, Expect=8e-96]} {Dmel: FBgn0000083, AnxB9, Annexin B9, [Score=259, Expect=4e-82]} {Celegans: WBGene00003589, nex-2, Annexin, [Score=261, Expect=2e-81]} {Smed: dd_Smed_v6_1735_0_1, dd_Smed_v6_1735_0_1, [Score=270, Expect=6e-86]} {RNA1509_5239} {RNA1310_11340, RNA1509_5239} {RNA1509_5239, RNA815_3977}
10. MligTC455_07623 797 16.6 Mlig455_048459

Neo: -

Age: Down-Up-Down

 STOM 1.695 - - - 0.966 0.729 - Mlig455_048459 {REF} {Length: 2249} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=40.3]} {Human: ENSG00000148175, STOM, stomatin, [Score=157, Expect=4e-48]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [Score=159, Expect=3e-49]} {Dmel: FBgn0260657, CG42540, [Score=158, Expect=1e-47]} {Celegans: WBGene00006068, sto-6, STOmatin, [Score=159, Expect=5e-49]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [Score=185, Expect=1e-59]} {RNA1509_9137} {RNA1310_11482.1} {RNA815_6842}
11. MligTC455_46083 2220 46.24 Mlig455_043359

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.366

 MVP 1.67 - - - - 0.965 0.705 Mlig455_043359 {REF} {Length: 3456} {Pfam: Major Vault Protein repeat domain [PF01505.20, score=217.8]; Shoulder domain [PF11978.10, score=163.9]; Major Vault Protein repeat domain [PF17794.3, score=121.1]; Major Vault Protein Repeat domain [PF17795.3, score=115.1]; Major Vault Protein repeat domain [PF17796.3, score=102.0]} {Human: ENSG00000013364, MVP, major vault protein, [RH, Score=1073, Expect=0.0]} {Mouse: ENSMUSG00000030681, Mvp, major vault protein, [RH, Score=1069, Expect=0.0]} {Smed: dd_Smed_v6_1098_0_1, dd_Smed_v6_1098_0_1, [Score=1073, Expect=0.0]} {RNA1509_27998, RNA1509_28665, RNA1509_40420} {RNA1310_3408.1, RNA1509_27998, RNA1509_40420} {RNA1509_27998, RNA1509_40420, RNA815_968.1}
12. MligTC455_41980 1108 23.09 Mlig455_048223

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.452

Regeneration-depleted BL: -2.044
Regeneration-depleted R6: -1.918

 1.668 - - - 0.715 0.953 - Mlig455_048223 {REF} {Length: 1924} {Pfam: Domain of unknown function (DUF1330) [PF07045.13, score=28.5]} {Smed: dd_Smed_v6_8243_0_1, dd_Smed_v6_8243_0_1, [Score=117, Expect=5e-31]} {RNA1509_5489} {RNA1310_15598} {RNA815_10198.1}
13. MligTC455_47216 803 16.72 Mlig455_052798

Neo: -

Age: -

 1.666 - - - - 0.956 0.710 Mlig455_052798 {REF} {Length: 4690} {TRANSSPLICED} {Pfam: Arginine/serine-rich protein PNISR [PF15996.7, score=44.6]} {RNA1509_22491} {RNA1310_7215.1, RNA1509_22491} {RNA1509_22491, RNA815_6578.1}
14. MligTC455_23642 573 11.93 Mlig455_069008

Neo: -

Age: logFC(26M/2M)=0.738

 ACTB 1.663 - - - - 0.950 0.713 Mlig455_069008 {REF} {Length: 2243} {Pfam: Actin [PF00022.21, score=267.5]; Protein kinase domain [PF00069.27, score=203.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=134.6]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=20.5]} {Human: ENSG00000075624, ACTB, actin beta, [Score=417, Expect=3e-141]; ENSG00000184009, ACTG1, actin gamma 1, [Score=417, Expect=5e-141]; ENSG00000107796, ACTA2, actin, alpha 2, smooth muscle, aorta, [Score=404, Expect=4e-136]; ENSG00000163017, ACTG2, actin, gamma 2, smooth muscle, enteric, [Score=404, Expect=5e-136]; ENSG00000159251, ACTC1, actin, alpha, cardiac muscle 1, [Score=403, Expect=2e-135]; ENSG00000169067, ACTBL2, actin, beta like 2, [Score=401, Expect=9e-135]; ENSG00000143632, ACTA1, actin, alpha 1, skeletal muscle, [Score=400, Expect=1e-134]} {Mouse: ENSMUSG00000062825, Actg1, actin, gamma, cytoplasmic 1, [Score=417, Expect=4e-141]; ENSMUSG00000029580, Actb, actin, beta, [Score=417, Expect=2e-141]; ENSMUSG00000035783, Acta2, actin, alpha 2, smooth muscle, aorta, [Score=404, Expect=2e-136]; ENSMUSG00000059430, Actg2, actin, gamma 2, smooth muscle, enteric, [Score=404, Expect=4e-136]; ENSMUSG00000055194, Actbl2, actin, beta-like 2, [Score=404, Expect=5e-136]; ENSMUSG00000068614, Actc1, actin, alpha, cardiac muscle 1, [Score=403, Expect=1e-135]; ENSMUSG00000031972, Acta1, actin, alpha 1, skeletal muscle, [Score=400, Expect=8e-135]} {Dmel: FBgn0000042, Act5C, Actin 5C, [Score=417, Expect=3e-141]} {Celegans: WBGene00000064, act-2, Actin-2, [Score=418, Expect=6e-142]} {Smed: dd_Smed_v6_3_0_1, dd_Smed_v6_3_0_1, [Score=419, Expect=4e-142]} {RNA1509_28185} {RNA1310_11665} {RNA815_6928}
15. MligTC455_46888 3493 72.77 Mlig455_023236

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.334

Regeneration-downregulated TP: -1.196

Regeneration-depleted TP: -1.196

 SLC25A14 1.659 - - - 0.951 0.708 - Mlig455_023236 {REF} {Length: 4876} {Pfam: Mitochondrial carrier protein [PF00153.29, score=159.1]} {Human: ENSG00000102078, SLC25A14, solute carrier family 25 member 14, [Score=216, Expect=1e-68]; ENSG00000174032, SLC25A30, solute carrier family 25 member 30, [Score=213, Expect=2e-68]} {Mouse: ENSMUSG00000031105, Slc25a14, solute carrier family 25 (mitochondrial carrier, brain), member 14, [Score=218, Expect=2e-69]; ENSMUSG00000022003, Slc25a30, solute carrier family 25, member 30, [Score=213, Expect=6e-68]} {Dmel: FBgn0036199, Bmcp, [Score=186, Expect=2e-57]} {Celegans: WBGene00015186, misc-1, MItochondrial Solute Carrier, [Score=137, Expect=1e-38]} {Smed: dd_Smed_v6_8945_0_8, dd_Smed_v6_8945_0_8, [Score=186, Expect=1e-57]} {RNA1509_23992, RNA1509_51810} {RNA1310_10029, RNA1509_51810} {RNA1509_51810, RNA815_7763.1}
16. MligTC455_12986 520 10.83 Mlig455_053026

Neo: -

Age: -

 LOXHD1 1.655 - 0.701 - - 0.954 - Mlig455_053026 {REF} {Length: 4034} {Pfam: PLAT/LH2 domain [PF01477.25, score=112.3]} {Human: ENSG00000167210, LOXHD1, lipoxygenase homology domains 1, [Score=93.6, Expect=2e-18]} {Mouse: ENSMUSG00000032818, Loxhd1, lipoxygenase homology domains 1, [Score=89.7, Expect=2e-17]} {Smed: dd_Smed_v6_10460_0_1, dd_Smed_v6_10460_0_1, [Score=108, Expect=1e-23]} {RNA1509_6796} {RNA1310_2867.1} {RNA815_966}
17. MligTC455_12985 171 3.57 Mlig455_052961

Neo: -

Age: -

 LOXHD1 0.974 - - - - 0.974 - Mlig455_052961 {REF} {Length: 4152} {Pfam: PLAT/LH2 domain [PF01477.25, score=111.3]} {Human: ENSG00000167210, LOXHD1, lipoxygenase homology domains 1, [Score=91.3, Expect=1e-17]} {Mouse: ENSMUSG00000032818, Loxhd1, lipoxygenase homology domains 1, [Score=87.8, Expect=8e-17]} {Smed: dd_Smed_v6_10460_0_1, dd_Smed_v6_10460_0_1, [Score=102, Expect=8e-22]} {RNA1509_6796} {RNA1310_2867.1} {RNA815_966}
18. MligTC455_43375 367 7.65 Mlig455_003848

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.356

 COL24A1 0.97 - - - - 0.970 - Mlig455_003848 {REF} {Length: 4716} {Pfam: Collagen triple helix repeat (20 copies) [PF01391.20, score=496.0]; Fibrillar collagen C-terminal domain [PF01410.20, score=111.2]} {Human: ENSG00000171502, COL24A1, collagen type XXIV alpha 1 chain, [Score=371, Expect=1e-105]} {Mouse: ENSMUSG00000029661, Col1a2, collagen, type I, alpha 2, [RH, Score=378, Expect=2e-109]} {Dmel: FBgn0000299, Col4a1, Collagen type IV alpha 1, [Score=343, Expect=2e-96]} {Celegans: WBGene00001263, emb-9, Collagen alpha-1(IV) chain, [Score=291, Expect=4e-80]} {Smed: dd_Smed_v6_8075_0_1, dd_Smed_v6_8075_0_1, [Score=478, Expect=2e-144]} {RNA1509_4709} {RNA1310_1394, RNA1509_4709} {RNA1509_4709, RNA815_513}
19. MligTC455_24630 962 20.04 Mlig455_067759

Neo: -

Age: -

 0.969 - - - - 0.969 - Mlig455_067759 {REF} {Length: 5477} {Pfam: RhoGEF domain [PF00621.22, score=30.3]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=21.0]} {RNA1509_7176} {RNA1310_1343.1} {RNA815_2798}
20. MligTC455_53434 3228 67.25 Mlig455_028543

Neo: -

Age: logFC(26M/2M)=-0.260

 RSPH4A 0.969 - - - - 0.969 - Mlig455_028543 {REF} {Length: 2028} {TRANSSPLICED} {Pfam: Radial spokehead-like protein [PF04712.14, score=618.3]} {Human: ENSG00000111834, RSPH4A, radial spoke head component 4A, [RH, Score=441, Expect=1e-147]} {Mouse: ENSMUSG00000039552, Rsph4a, radial spoke head 4 homolog A (Chlamydomonas), [Score=447, Expect=6e-150]} {Dmel: FBgn0034957, CG3121, [Score=227, Expect=6e-66]} {Smed: dd_Smed_v6_5346_0_1, dd_Smed_v6_5346_0_1, [RH, Score=456, Expect=2e-156]} {RNA1509_18862, RNA1509_6840, RNA1509_800} {RNA1310_12717.1, RNA1509_18862, RNA1509_6840, RNA1509_800} {RNA1509_18862, RNA1509_6840, RNA1509_800, RNA815_4800.1}
21. MligTC455_24001 531 11.07 Mlig455_036318

Neo: -

Age: Up-Down-Down

 DNAH3 0.968 - - - - 0.968 - Mlig455_036318 {REF} {Length: 13102} {TRANSSPLICED} {Pfam: Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=527.0]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=479.4]; Dynein heavy chain C-terminal domain [PF18199.3, score=409.8]; P-loop containing dynein motor region D4 [PF12780.9, score=366.0]; ATP-binding dynein motor region [PF12781.9, score=303.3]; P-loop containing dynein motor region [PF12775.9, score=274.8]; Dynein heavy chain AAA lid domain [PF18198.3, score=187.8]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=157.6]; Dynein heavy chain AAA lid domain [PF17852.3, score=124.6]; Microtubule-binding stalk of dynein motor [PF12777.9, score=124.5]; AAA+ lid domain [PF17857.3, score=66.8]; AAA domain (dynein-related subfamily) [PF07728.16, score=64.9]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=29.9]; AAA ATPase domain [PF13191.8, score=20.6]; RNA helicase [PF00910.24, score=20.1]} {Human: ENSG00000158486, DNAH3, dynein axonemal heavy chain 3, [RH, Score=5014, Expect=0.0]} {Mouse: ENSMUSG00000052273, Dnah3, dynein, axonemal, heavy chain 3, [RH, Score=5030, Expect=0.0]} {Dmel: FBgn0035581, Dnah3, dynein, axonemal, heavy chain 3, [RH, Score=3534, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=699, Expect=0.0]} {Smed: dd_Smed_v6_6941_0_1, dd_Smed_v6_6941_0_1, [Score=3807, Expect=0.0]} {RNA1509_389} {RNA1310_53.1} {RNA815_33.1}
22. MligTC455_22198 766 15.95 Mlig455_054315

Neo: -

Age: -

 DCDC1 0.964 - - - - 0.964 - Mlig455_054315 {REF} {Length: 7168} {Pfam: Cep120 protein [PF12416.10, score=49.6]; Doublecortin [PF03607.19, score=39.3]; KHA, dimerisation domain of potassium ion channel [PF11834.10, score=22.6]; CIDE-N domain [PF02017.17, score=21.0]} {Human: ENSG00000170959, DCDC1, doublecortin domain containing 1, [RH, Score=399, Expect=1e-112]} {Smed: dd_Smed_v6_11770_0_1, dd_Smed_v6_11770_0_1, [RH, Score=297, Expect=6e-81]} {RNA1509_1192} {RNA1310_347} {RNA815_115}
23. MligTC455_23445 11181 232.93 Mlig455_016960, Mlig455_059585, Mlig455_069851

Neo: -

Age: logFC(26M/2M)=-0.114

 MUT 0.964 - - - - 0.964 -

Mlig455_016960 {REF} {Length: 3018} {TRANSSPLICED} {Pfam: Methylmalonyl-CoA mutase [PF01642.24, score=726.3]; B12 binding domain [PF02310.21, score=54.0]} {Human: ENSG00000146085, MUT, methylmalonyl-CoA mutase, [RH, Score=982, Expect=0.0]} {Mouse: ENSMUSG00000023921, Mut, methylmalonyl-Coenzyme A mutase, [RH, Score=982, Expect=0.0]} {Celegans: WBGene00014202, mmcm-1, Probable methylmalonyl-CoA mutase, mitochondrial, [RH, Score=982, Expect=0.0]} {Smed: dd_Smed_v6_2255_0_1, dd_Smed_v6_2255_0_1, [RH, Score=997, Expect=0.0]} {RNA1509_779} {RNA1310_5402.1, RNA1509_779} {RNA1509_779, RNA815_1637}

Mlig455_059585 {REF} {Length: 3023} {TRANSSPLICED} {Pfam: Methylmalonyl-CoA mutase [PF01642.24, score=726.3]; B12 binding domain [PF02310.21, score=54.0]} {Human: ENSG00000146085, MUT, methylmalonyl-CoA mutase, [RH, Score=982, Expect=0.0]} {Mouse: ENSMUSG00000023921, Mut, methylmalonyl-Coenzyme A mutase, [RH, Score=982, Expect=0.0]} {Celegans: WBGene00014202, mmcm-1, Probable methylmalonyl-CoA mutase, mitochondrial, [RH, Score=982, Expect=0.0]} {Smed: dd_Smed_v6_2255_0_1, dd_Smed_v6_2255_0_1, [RH, Score=997, Expect=0.0]} {RNA1509_16567, RNA1509_779} {RNA1310_5402.1, RNA1509_16567} {RNA1509_16567, RNA815_1637}

Mlig455_069851 {REF} {Length: 3027} {TRANSSPLICED} {Pfam: Methylmalonyl-CoA mutase [PF01642.24, score=724.9]; B12 binding domain [PF02310.21, score=54.1]} {Human: ENSG00000146085, MUT, methylmalonyl-CoA mutase, [RH, Score=985, Expect=0.0]} {Mouse: ENSMUSG00000023921, Mut, methylmalonyl-Coenzyme A mutase, [RH, Score=985, Expect=0.0]} {Celegans: WBGene00014202, mmcm-1, Probable methylmalonyl-CoA mutase, mitochondrial, [RH, Score=984, Expect=0.0]} {Smed: dd_Smed_v6_2255_0_1, dd_Smed_v6_2255_0_1, [RH, Score=1000, Expect=0.0]} {RNA1509_3447, RNA1509_779} {RNA1310_5402.1, RNA1509_3447} {RNA1509_3447, RNA815_1637}
24. MligTC455_53091 542 11.29 Mlig455_061253

Neo: -

Age: -

 SPATA1 0.964 - - - - 0.964 - Mlig455_061253 {REF} {Length: 3411} {Pfam: Spermatogenesis-associated C-terminus [PF15743.7, score=145.3]} {Human: ENSG00000122432, SPATA1, spermatogenesis associated 1, [Score=108, Expect=2e-24]} {Mouse: ENSMUSG00000028188, Spata1, spermatogenesis associated 1, [Score=110, Expect=4e-25]} {Smed: dd_Smed_v6_15381_0_1, dd_Smed_v6_15381_0_1, [RH, Score=174, Expect=1e-46]} {RNA1509_56521} {RNA1310_8534} {RNA815_3401.1}
25. MligTC455_13001 3958 82.45 Mlig455_058752

Neo: -

Age: logFC(26M/2M)=-0.388

 CALML3 0.962 - - - 0.962 - - Mlig455_058752 {REF} {Length: 1160} {Pfam: EF hand [PF00036.34, score=117.6]; EF-hand domain pair [PF13499.8, score=111.2]; EF-hand domain [PF13405.8, score=93.1]; EF hand [PF13202.8, score=91.8]; EF-hand domain pair [PF13833.8, score=82.4]; EF-hand domain [PF14658.8, score=44.9]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=38.0]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=32.1]; Tellurite resistance protein TerB [PF05099.15, score=19.5]} {Human: ENSG00000178363, CALML3, calmodulin like 3, [Score=116, Expect=5e-33]; ENSG00000160014, CALM3, calmodulin 3, [Score=115, Expect=1e-32]; ENSG00000198668, CALM1, calmodulin 1, [Score=115, Expect=7e-33]; ENSG00000143933, CALM2, calmodulin 2, [Score=115, Expect=1e-32]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=115, Expect=7e-33]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=115, Expect=7e-33]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=115, Expect=7e-33]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=112, Expect=6e-32]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=112, Expect=5e-32]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=112, Expect=4e-32]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=112, Expect=3e-32]} {RNA1509_6844} {RNA1310_36879} {RNA815_5954.1}
26. MligTC455_22197 774 16.13 Mlig455_003800

Neo: -

Age: -

 DCDC1 0.962 - - - - 0.962 - Mlig455_003800 {REF} {Length: 7175} {Pfam: Doublecortin [PF03607.19, score=36.2]; KHA, dimerisation domain of potassium ion channel [PF11834.10, score=20.0]} {Human: ENSG00000170959, DCDC1, doublecortin domain containing 1, [Score=248, Expect=7e-66]} {Smed: dd_Smed_v6_11770_0_1, dd_Smed_v6_11770_0_1, [Score=213, Expect=2e-55]} {RNA1509_1192} {RNA1310_347} {RNA815_115}
27. MligTC455_30342 208 4.33 Mlig455_043135

Neo: -

Age: Down-Down-Down

 SLC5A8 0.962 - - - - 0.962 - Mlig455_043135 {REF} {Length: 2083} {TRANSSPLICED} {Pfam: Sodium:solute symporter family [PF00474.19, score=70.7]} {Human: ENSG00000256870, SLC5A8, solute carrier family 5 member 8, [Score=246, Expect=9e-72]; ENSG00000262217, SLC5A8, solute carrier family 5 member 8, [Score=246, Expect=9e-72]} {Mouse: ENSMUSG00000020062, Slc5a8, solute carrier family 5 (iodide transporter), member 8, [Score=247, Expect=2e-72]} {Dmel: FBgn0034494, CG10444, [Score=222, Expect=2e-63]} {Celegans: WBGene00014092, ZK822.5, [Score=180, Expect=1e-48]} {Smed: dd_Smed_v6_14173_0_1, dd_Smed_v6_14173_0_1, [Score=240, Expect=2e-70]} {RNA1509_5005} {RNA1310_577.1} {RNA815_4301}
28. MligTC455_20070 2764 57.59 Mlig455_018898, Mlig455_064935

Neo: -

Age: logFC(26M/2M)=-0.311

 AXDND1 0.959 - - - - 0.959 -

Mlig455_018898 {REF} {Length: 3733} {TRANSSPLICED} {Pfam: Axonemal dynein light chain [PF10211.11, score=41.1]} {Human: ENSG00000162779, AXDND1, axonemal dynein light chain domain containing 1, [RH, Score=406, Expect=5e-124]} {Mouse: ENSMUSG00000026601, Axdnd1, axonemal dynein light chain domain containing 1, [RH, Score=401, Expect=1e-121]} {Smed: dd_Smed_v6_17219_0_1, dd_Smed_v6_17219_0_1, [RH, Score=436, Expect=1e-135]} {RNA1509_4031} {RNA1310_3220.1} {RNA815_882.1}

Mlig455_064935 {REF} {Length: 3676} {TRANSSPLICED} {Pfam: Axonemal dynein light chain [PF10211.11, score=39.8]} {Human: ENSG00000162779, AXDND1, axonemal dynein light chain domain containing 1, [RH, Score=417, Expect=2e-128]} {Mouse: ENSMUSG00000026601, Axdnd1, axonemal dynein light chain domain containing 1, [RH, Score=410, Expect=4e-125]} {Smed: dd_Smed_v6_17219_0_1, dd_Smed_v6_17219_0_1, [RH, Score=440, Expect=3e-137]} {RNA1509_12971, RNA1509_51405} {RNA1310_3220.1, RNA1509_51405} {RNA1509_51405, RNA815_882.1}
29. MligTC455_31756 2000 41.66 Mlig455_008900, Mlig455_016594

Neo: -

Age: Down-Up-Down

 ATP6V1E1 0.959 - - - - - 0.959

Mlig455_008900 {REF} {Length: 2185} {Pfam: ATP synthase (E/31 kDa) subunit [PF01991.20, score=215.1]} {Human: ENSG00000131100, ATP6V1E1, ATPase H+ transporting V1 subunit E1, [RH, Score=259, Expect=2e-87]} {Mouse: ENSMUSG00000019210, Atp6v1e1, ATPase, H+ transporting, lysosomal V1 subunit E1, [RH, Score=257, Expect=9e-87]} {Dmel: FBgn0283535, Vha26, Vacuolar H[+]-ATPase 26kD subunit, [RH, Score=268, Expect=2e-91]} {Celegans: WBGene00006917, vha-8, Vacuolar H ATPase, [RH, Score=265, Expect=4e-90]} {Smed: dd_Smed_v6_1369_0_1, dd_Smed_v6_1369_0_1, [RH, Score=230, Expect=1e-76]} {RNA1509_6136} {RNA1310_37070.1, RNA1509_6136} {RNA1509_6136, RNA815_17454}

Mlig455_016594 {REF} {Length: 2127} {TRANSSPLICED} {Pfam: ATP synthase (E/31 kDa) subunit [PF01991.20, score=215.1]} {Human: ENSG00000131100, ATP6V1E1, ATPase H+ transporting V1 subunit E1, [RH, Score=259, Expect=2e-87]} {Mouse: ENSMUSG00000019210, Atp6v1e1, ATPase, H+ transporting, lysosomal V1 subunit E1, [RH, Score=257, Expect=9e-87]} {Dmel: FBgn0283535, Vha26, Vacuolar H[+]-ATPase 26kD subunit, [RH, Score=268, Expect=2e-91]} {Celegans: WBGene00006917, vha-8, Vacuolar H ATPase, [RH, Score=265, Expect=4e-90]} {Smed: dd_Smed_v6_1369_0_1, dd_Smed_v6_1369_0_1, [RH, Score=230, Expect=1e-76]} {RNA1509_6136} {RNA1310_37070.1} {RNA815_17454}
30. MligTC455_18106 1217 25.35 Mlig455_066402

Neo: -

Age: -

 C7orf31 0.958 - - - - 0.958 - Mlig455_066402 {REF} {Length: 3205} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4555) [PF15093.8, score=102.0]} {Human: ENSG00000153790, C7orf31, chromosome 7 open reading frame 31, [RH, Score=119, Expect=3e-27]} {Mouse: ENSMUSG00000029828, 4921507P07Rik, RIKEN cDNA 4921507P07 gene, [RH, Score=110, Expect=1e-24]} {RNA1509_11592} {RNA1310_4450} {RNA815_12248}
31. MligTC455_33249 323 6.73 Mlig455_041967, Mlig455_042041

Neo: -

Age: -

 0.957 - - - - 0.957 -

Mlig455_041967 {REF} {Length: 6188} {RNA1509_21815} {RNA1310_798} {RNA815_11352}

Mlig455_042041 {REF} {Length: 6176} {Pfam: Putative DNA-binding domain [PF04326.16, score=20.8]} {RNA1509_21815} {RNA1310_798, RNA1509_21815} {RNA1509_21815, RNA815_11352}
32. MligTC455_17235 216 4.51 Mlig455_058265

Neo: -

Age: -

 ANO7 0.956 - - - - 0.956 - Mlig455_058265 {REF} {Length: 1888} {Pfam: Calcium-activated chloride channel [PF04547.14, score=264.3]} {Human: ENSG00000146205, ANO7, anoctamin 7, [Score=394, Expect=4e-129]} {Mouse: ENSMUSG00000034107, Ano7, anoctamin 7, [Score=392, Expect=9e-130]} {Dmel: FBgn0038721, subdued, [Score=268, Expect=5e-82]} {Celegans: WBGene00013326, anoh-2, Anoctamin, [Score=85.1, Expect=9e-18]} {Smed: dd_Smed_v6_19189_0_1, dd_Smed_v6_19189_0_1, [Score=476, Expect=2e-164]} {RNA1509_15570} {RNA1310_7822} {RNA815_20477}
33. MligTC455_49635 2917 60.78 Mlig455_021335

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.377

 LRTOMT 0.956 - - - 0.956 - - Mlig455_021335 {REF} {Length: 944} {Pfam: Leucine Rich repeats (2 copies) [PF12799.9, score=44.2]; Leucine-rich repeat [PF14580.8, score=43.9]; Leucine rich repeat [PF13855.8, score=36.8]} {Human: ENSG00000184154, LRTOMT, leucine rich transmembrane and O-methyltransferase domain containing, [RH, Score=145, Expect=4e-43]} {Mouse: ENSMUSG00000064307, Lrrc51, leucine rich repeat containing 51, [RH, Score=149, Expect=6e-45]} {Celegans: WBGene00003390, mog-2, Probable U2 small nuclear ribonucleoprotein A', [Score=59.3, Expect=2e-10]} {Smed: dd_Smed_v6_8583_0_1, dd_Smed_v6_8583_0_1, [RH, Score=170, Expect=4e-53]} {RNA1509_7051} {RNA1310_42278, RNA1509_7051} {RNA1509_7051, RNA815_19576}
34. MligTC455_35296 3716 77.42 Mlig455_021730

Neo: -

Age: logFC(26M/2M)=-0.211

 RAB11B 0.955 - - - 0.955 - - Mlig455_021730 {REF} {Length: 4827} {Pfam: Ras family [PF00071.24, score=161.7]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=109.2]; ADP-ribosylation factor family [PF00025.23, score=50.2]; 50S ribosome-binding GTPase [PF01926.25, score=28.2]; RsgA GTPase [PF03193.18, score=19.7]} {Human: ENSG00000185236, RAB11B, RAB11B, member RAS oncogene family, [Score=146, Expect=6e-39]} {Mouse: ENSMUSG00000077450, Rab11b, RAB11B, member RAS oncogene family, [Score=145, Expect=5e-39]; ENSMUSG00000079657, Rab26, RAB26, member RAS oncogene family, [Score=139, Expect=1e-35]; ENSMUSG00000004771, Rab11a, RAB11A, member RAS oncogene family, [Score=138, Expect=2e-36]} {Dmel: FBgn0015790, Rab11, [Score=139, Expect=6e-37]} {Celegans: WBGene00004271, rab-7, RAB family, [Score=135, Expect=8e-36]} {Smed: dd_Smed_v6_4001_0_1, dd_Smed_v6_4001_0_1, [Score=136, Expect=3e-36]} {RNA1509_48652, RNA1509_48880, RNA1509_8793, RNA1509_9768} {RNA1310_4344.1, RNA1509_48652, RNA1509_48880, RNA1509_8793} {RNA1509_48652, RNA1509_48880, RNA1509_8793, RNA815_5085}
35. MligTC455_41039 820 17.08 Mlig455_012731

Neo: -

Age: -

 FLRT1 0.952 - - - - 0.952 - Mlig455_012731 {REF} {Length: 2045} {Pfam: Leucine rich repeat [PF13855.8, score=60.6]; Leucine Rich repeats (2 copies) [PF12799.9, score=47.8]; Leucine-rich repeat [PF14580.8, score=22.6]} {Human: ENSG00000126500, FLRT1, fibronectin leucine rich transmembrane protein 1, [Score=67.4, Expect=3e-11]; ENSG00000187122, SLIT1, slit guidance ligand 1, [Score=67.0, Expect=6e-11]; ENSG00000011465, DCN, decorin, [Score=66.2, Expect=4e-11]; ENSG00000184347, SLIT3, slit guidance ligand 3, [Score=65.5, Expect=2e-10]} {Mouse: ENSMUSG00000056427, Slit3, slit guidance ligand 3, [Score=67.0, Expect=4e-11]; ENSMUSG00000025020, Slit1, slit guidance ligand 1, [Score=66.6, Expect=6e-11]; ENSMUSG00000047787, Flrt1, fibronectin leucine rich transmembrane protein 1, [Score=66.2, Expect=6e-11]} {Dmel: FBgn0036995, atk, artichoke, [Score=64.7, Expect=2e-10]} {Celegans: WBGene00020649, sma-10, Leucine-rich repeats and immunoglobulin-like domains protein sma-10, [Score=72.4, Expect=4e-13]} {Smed: dd_Smed_v6_12111_0_1, dd_Smed_v6_12111_0_1, [Score=64.3, Expect=1e-10]} {RNA1509_45627, RNA1509_8353} {RNA1310_14213, RNA1509_45627, RNA1509_8353} {RNA1509_45627, RNA1509_8353, RNA815_5583}
36. MligTC455_44180 259 5.39 Mlig455_037643

Neo: -

Age: -

 TRIM3 0.951 - - - - 0.951 - Mlig455_037643 {REF} {Length: 2363} {Pfam: Ring finger domain [PF13639.8, score=26.1]; RING-type zinc-finger [PF13445.8, score=24.5]; Prokaryotic RING finger family 4 [PF14447.8, score=22.8]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=22.5]; zinc finger of C3HC4-type, RING [PF15227.8, score=22.4]; zinc-RING finger domain [PF14634.8, score=22.1]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=21.4]; RING-H2 zinc finger domain [PF12678.9, score=19.8]} {Human: ENSG00000110171, TRIM3, tripartite motif containing 3, [Score=55.8, Expect=2e-07]} {Mouse: ENSMUSG00000036989, Trim3, tripartite motif-containing 3, [Score=55.1, Expect=2e-07]} {Celegans: WBGene00003597, nhl-1, RING finger protein nhl-1, [Score=48.5, Expect=1e-05]} {Smed: dd_Smed_v6_2039_0_1, dd_Smed_v6_2039_0_1, [Score=155, Expect=6e-41]} {RNA1509_28145} {RNA1310_10684, RNA1509_28145} {RNA1509_28145, RNA815_4887}
37. MligTC455_42003 140 2.91 Mlig455_022863

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.408

 GFRA3 0.95 - - - - 0.950 - Mlig455_022863 {REF} {Length: 4157} {Pfam: GDNF/GAS1 domain [PF02351.18, score=44.8]} {Human: ENSG00000146013, GFRA3, GDNF family receptor alpha 3, [RH, Score=53.9, Expect=7e-07]} {RNA1509_30984} {RNA1310_17179, RNA1509_30984} {RNA1509_30984, RNA815_27672}
38. MligTC455_49143 772 16.08 Mlig455_021704

Neo: -

Age: -

Region-enriched R2: 1.427/0.03420

 0.95 - - - - 0.950 - Mlig455_021704 {REF} {Length: 2489} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4537) [PF15057.8, score=48.8]} {Smed: dd_Smed_v6_13233_0_2, dd_Smed_v6_13233_0_2, [Score=60.1, Expect=4e-09]} {RNA1509_11962} {RNA1310_8951.1, RNA1509_11962}
39. MligTC455_49820 221 4.61 Mlig455_002983, Mlig455_055617

Neo: -

Age: -

 ELMOD3 0.95 - - - - 0.950 -

Mlig455_002983 {REF} {Length: 2211} {TRANSSPLICED} {Pfam: ELMO/CED-12 family [PF04727.15, score=93.0]} {Human: ENSG00000115459, ELMOD3, ELMO domain containing 3, [RH, Score=176, Expect=1e-49]} {Mouse: ENSMUSG00000056698, Elmod3, ELMO/CED-12 domain containing 3, [RH, Score=176, Expect=8e-50]} {Dmel: FBgn0037473, CG10068, [Score=51.6, Expect=7e-07]} {Celegans: WBGene00008348, C56G7.3, ELMO domain-containing protein C56G7.3, [RH, Score=77.8, Expect=1e-15]} {Smed: dd_Smed_v6_13608_0_1, dd_Smed_v6_13608_0_1, [RH, Score=108, Expect=5e-26]} {RNA1509_18531} {RNA1310_8712} {RNA815_4449}

Mlig455_055617 {REF} {Length: 1765} {TRANSSPLICED} {Pfam: ELMO/CED-12 family [PF04727.15, score=92.8]} {Human: ENSG00000115459, ELMOD3, ELMO domain containing 3, [RH, Score=164, Expect=1e-44]} {Mouse: ENSMUSG00000056698, Elmod3, ELMO/CED-12 domain containing 3, [RH, Score=157, Expect=5e-43]} {Dmel: FBgn0037473, CG10068, [Score=52.4, Expect=5e-07]} {Celegans: WBGene00008348, C56G7.3, ELMO domain-containing protein C56G7.3, [Score=73.2, Expect=5e-14]} {Smed: dd_Smed_v6_13608_0_1, dd_Smed_v6_13608_0_1, [Score=100, Expect=2e-23]} {RNA1509_18531} {RNA1310_8712} {RNA815_4449}

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