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Results for MligTC455_41980

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_41980 1108 23.09 Mlig455_048223

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.452

Regeneration-depleted BL: -2.044
Regeneration-depleted R6: -1.918

Mlig455_048223 {REF} {Length: 1924} {Pfam: Domain of unknown function (DUF1330) [PF07045.13, score=28.5]} {Smed: dd_Smed_v6_8243_0_1, dd_Smed_v6_8243_0_1, [Score=117, Expect=5e-31]} {RNA1509_5489} {RNA1310_15598} {RNA815_10198.1}

Cumulative graph for MligTC455_41980

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.007 4.664 0.99368 1.00000
RegionR2 0.563 4.664 0.08273 0.35269
RegionR3 0.198 4.664 0.45267 0.96392
RegionR4 0.254 4.664 0.44744 0.77672
RegionR5 -0.597 4.664 0.02759 0.12201
RegionR6 0.171 4.664 0.53085 1.00000
RegionR7 -0.65 4.664 0.08765 0.56803
RegionR8 0.067 4.664 0.87357 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.534 4.664 0.23682 0.96575
RegenerationR2 -0.559 4.664 0.03383 0.30358
RegenerationR3 -0.996 4.664 0.00129 0.05882
RegenerationR4 -0.898 4.664 0.00590 0.11011
RegenerationR5 -0.708 4.664 0.02499 0.26931
RegenerationR6 -1.918 4.664 0.00000 0.00004
RegenerationBL -2.044 4.664 0.00005 0.00276
RegenerationTP -1.304 4.664 0.00599 0.13011


Genes with expression patterns similar to MligTC455_41980

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_41980 1108 23.09 Mlig455_048223

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.452

Regeneration-depleted BL: -2.044
Regeneration-depleted R6: -1.918

6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_048223 {REF} {Length: 1924} {Pfam: Domain of unknown function (DUF1330) [PF07045.13, score=28.5]} {Smed: dd_Smed_v6_8243_0_1, dd_Smed_v6_8243_0_1, [Score=117, Expect=5e-31]} {RNA1509_5489} {RNA1310_15598} {RNA815_10198.1}
2. MligTC455_28345 2571 53.57 Mlig455_019103

Neo: -

Age: Down-Up-Up

SAXO1 3.559 - - 0.902 0.861 0.958 0.838 Mlig455_019103 {REF} {Length: 3161} {Human: ENSG00000155875, SAXO1, stabilizer of axonemal microtubules 1, [RH, Score=212, Expect=8e-63]} {Mouse: ENSMUSG00000038570, Saxo2, stabilizer of axonemal microtubules 2, [RH, Score=176, Expect=4e-50]} {Celegans: WBGene00011630, T08G11.3, [RH, Score=76.3, Expect=1e-14]} {Smed: dd_Smed_v6_3695_0_1, dd_Smed_v6_3695_0_1, [RH, Score=475, Expect=2e-165]} {RNA1509_17442, RNA1509_28268, RNA1509_37997} {RNA1310_1293.1, RNA1509_28268, RNA1509_37997} {RNA1509_28268, RNA1509_37997, RNA815_1077}
3. MligTC455_28346 2683 55.89 Mlig455_019110

Neo: -

Age: -

SAXO1 3.45 - - 0.807 0.853 0.966 0.824 Mlig455_019110 {REF} {Length: 3338} {Human: ENSG00000155875, SAXO1, stabilizer of axonemal microtubules 1, [RH, Score=211, Expect=1e-62]} {Mouse: ENSMUSG00000038570, Saxo2, stabilizer of axonemal microtubules 2, [RH, Score=175, Expect=8e-50]} {Celegans: WBGene00011630, T08G11.3, [RH, Score=77.0, Expect=8e-15]} {Smed: dd_Smed_v6_3695_0_1, dd_Smed_v6_3695_0_1, [RH, Score=476, Expect=4e-166]} {RNA1509_13363, RNA1509_17442, RNA1509_2283, RNA1509_59104} {RNA1310_1293.1, RNA1509_13363, RNA1509_17442, RNA1509_2283, RNA1509_59104} {RNA1509_13363, RNA1509_17442, RNA1509_2283, RNA1509_59104, RNA815_1077}
4. MligTC455_53434 3228 67.25 Mlig455_028543

Neo: -

Age: logFC(26M/2M)=-0.260

RSPH4A 3.449 0.811 0.835 - - 0.979 0.824 Mlig455_028543 {REF} {Length: 2028} {TRANSSPLICED} {Pfam: Radial spokehead-like protein [PF04712.14, score=618.3]} {Human: ENSG00000111834, RSPH4A, radial spoke head component 4A, [RH, Score=441, Expect=1e-147]} {Mouse: ENSMUSG00000039552, Rsph4a, radial spoke head 4 homolog A (Chlamydomonas), [Score=447, Expect=6e-150]} {Dmel: FBgn0034957, CG3121, [Score=227, Expect=6e-66]} {Smed: dd_Smed_v6_5346_0_1, dd_Smed_v6_5346_0_1, [RH, Score=456, Expect=2e-156]} {RNA1509_18862, RNA1509_6840, RNA1509_800} {RNA1310_12717.1, RNA1509_18862, RNA1509_6840, RNA1509_800} {RNA1509_18862, RNA1509_6840, RNA1509_800, RNA815_4800.1}
5. MligTC455_51713 737 15.35 Mlig455_003554, Mlig455_015507

Neo: -

Age: logFC(26M/2M)=-0.192

ANKAR 3.448 0.758 - 0.878 - 0.860 0.952

Mlig455_003554 {REF} {Length: 5287} {TRANSSPLICED} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=131.3]; Ankyrin repeats (3 copies) [PF12796.9, score=56.3]; HEAT repeats [PF13646.8, score=38.5]; Ankyrin repeats (many copies) [PF13637.8, score=34.3]; Ankyrin repeat [PF13606.8, score=29.9]; Spinocerebellar ataxia type 10 protein domain [PF09759.11, score=29.3]; Ankyrin repeats (many copies) [PF13857.8, score=27.3]; Ankyrin repeat [PF00023.32, score=24.0]; V-ATPase subunit H [PF11698.10, score=21.3]} {Human: ENSG00000151687, ANKAR, ankyrin and armadillo repeat containing, [Score=782, Expect=0.0]} {Mouse: ENSMUSG00000039342, Ankar, ankyrin and armadillo repeat containing, [Score=829, Expect=0.0]} {Dmel: FBgn0016920, nompC, no mechanoreceptor potential C, [Score=60.5, Expect=1e-08]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=61.2, Expect=7e-09]} {Smed: dd_Smed_v6_13064_0_1, dd_Smed_v6_13064_0_1, [Score=843, Expect=0.0]} {RNA1509_7218} {RNA1310_1159.1} {RNA815_584.1}

Mlig455_015507 {REF} {Length: 5025} {TRANSSPLICED} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=141.1]; Ankyrin repeats (3 copies) [PF12796.9, score=61.3]; HEAT repeats [PF13646.8, score=45.1]; Ankyrin repeats (many copies) [PF13637.8, score=33.3]; Ankyrin repeat [PF13606.8, score=31.9]; Spinocerebellar ataxia type 10 protein domain [PF09759.11, score=29.0]; Ankyrin repeats (many copies) [PF13857.8, score=25.5]; V-ATPase subunit H [PF11698.10, score=25.0]; Ankyrin repeat [PF00023.32, score=24.8]; HEAT repeat [PF02985.24, score=21.2]} {Human: ENSG00000151687, ANKAR, ankyrin and armadillo repeat containing, [RH, Score=917, Expect=0.0]} {Mouse: ENSMUSG00000039342, Ankar, ankyrin and armadillo repeat containing, [RH, Score=917, Expect=0.0]} {Dmel: FBgn0016920, nompC, no mechanoreceptor potential C, [Score=61.2, Expect=8e-09]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=61.6, Expect=5e-09]} {Smed: dd_Smed_v6_13064_0_1, dd_Smed_v6_13064_0_1, [RH, Score=927, Expect=0.0]} {RNA1509_7218} {RNA1310_1159.1} {RNA815_584.1}
6. MligTC455_41200 1715 35.72 Mlig455_069721

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.691

CFAP45 3.163 0.731 0.731 - - 0.968 0.733 Mlig455_069721 {REF} {Length: 2678} {Pfam: Trichohyalin-plectin-homology domain [PF13868.8, score=268.3]} {Human: ENSG00000213085, CFAP45, cilia and flagella associated protein 45, [Score=327, Expect=2e-105]} {Mouse: ENSMUSG00000026546, Cfap45, cilia and flagella associated protein 45, [Score=317, Expect=1e-101]} {Dmel: FBgn0037162, CG11449, [RH, Score=114, Expect=1e-26]} {Smed: dd_Smed_v6_3732_0_1, dd_Smed_v6_3732_0_1, [Score=434, Expect=4e-147]} {RNA1509_11293, RNA1509_455, RNA1509_48510, RNA1509_5508} {RNA1310_7881.1, RNA1509_11293, RNA1509_48510, RNA1509_5508} {RNA1509_11293, RNA1509_48510, RNA1509_5508, RNA815_2376.1}
7. MligTC455_43293 2619 54.57 Mlig455_001393

Neo: -

Age: -

Region-specific R2: 1.579

ANXA7 2.787 - 0.891 - 0.966 0.930 - Mlig455_001393 {REF} {Length: 4698} {Pfam: Annexin [PF00191.22, score=268.6]} {Human: ENSG00000138279, ANXA7, annexin A7, [RH, Score=307, Expect=6e-98]} {Mouse: ENSMUSG00000021814, Anxa7, annexin A7, [RH, Score=301, Expect=8e-96]} {Dmel: FBgn0000083, AnxB9, Annexin B9, [Score=259, Expect=4e-82]} {Celegans: WBGene00003589, nex-2, Annexin, [Score=261, Expect=2e-81]} {Smed: dd_Smed_v6_1735_0_1, dd_Smed_v6_1735_0_1, [Score=270, Expect=6e-86]} {RNA1509_5239} {RNA1310_11340, RNA1509_5239} {RNA1509_5239, RNA815_3977}
8. MligTC455_48164 1129 23.52 Mlig455_020167

Neo: -

Age: logFC(26M/2M)=-0.425

2.607 - - - 0.804 0.848 0.955 Mlig455_020167 {REF} {Length: 1547} {RNA1509_31892} {RNA1310_30464, RNA1509_31892} {RNA1509_31892, RNA815_28823.1}
9. MligTC455_42496 3501 72.94 Mlig455_001645

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.276

DNAJB13 2.603 - 0.780 - 0.957 0.866 - Mlig455_001645 {REF} {Length: 1503} {Pfam: DnaJ C terminal domain [PF01556.20, score=137.8]; DnaJ domain [PF00226.33, score=80.4]} {Human: ENSG00000187726, DNAJB13, DnaJ heat shock protein family (Hsp40) member B13, [RH, Score=397, Expect=5e-139]} {Mouse: ENSMUSG00000030708, Dnajb13, DnaJ heat shock protein family (Hsp40) member B13, [RH, Score=399, Expect=5e-140]} {Dmel: FBgn0031322, CG5001, [RH, Score=310, Expect=1e-104]} {Celegans: WBGene00001031, dnj-13, DNaJ domain (Prokaryotic heat shock protein), [Score=283, Expect=1e-94]} {Smed: dd_Smed_v6_4820_0_1, dd_Smed_v6_4820_0_1, [RH, Score=424, Expect=3e-150]} {RNA1509_1609, RNA1509_23650, RNA1509_4723} {RNA1310_19642, RNA1509_1609, RNA1509_23650, RNA1509_4723} {RNA1509_1609, RNA1509_23650, RNA1509_4723, RNA815_9344}
10. MligTC455_31847 661 13.78 Mlig455_025501, Mlig455_070503

Neo: -

Age: Down-Up-Down

KCNMA1 2.589 - - 0.957 - 0.923 0.709

Mlig455_025501 {REF} {Length: 4552} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=85.2]; Ion channel [PF07885.18, score=43.4]; Ion transport protein [PF00520.33, score=34.6]; TrkA-N domain [PF02254.20, score=22.5]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=488, Expect=4e-154]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=335, Expect=3e-97]} {Dmel: FBgn0003429, slo, slowpoke, [Score=484, Expect=1e-151]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=454, Expect=9e-141]} {Smed: dd_Smed_v6_5509_0_1, dd_Smed_v6_5509_0_1, [Score=476, Expect=1e-149]} {RNA1509_14763} {RNA1310_2844.1} {RNA815_830}

Mlig455_070503 {REF} {Length: 4866} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=85.2]; Ion channel [PF07885.18, score=43.4]; Ion transport protein [PF00520.33, score=34.6]; TrkA-N domain [PF02254.20, score=22.5]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=488, Expect=4e-154]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=335, Expect=3e-97]} {Dmel: FBgn0003429, slo, slowpoke, [Score=484, Expect=1e-151]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=454, Expect=9e-141]} {Smed: dd_Smed_v6_5509_0_1, dd_Smed_v6_5509_0_1, [Score=476, Expect=1e-149]} {RNA1509_14763} {RNA1310_2844.1, RNA1509_14763} {RNA1509_14763, RNA815_830}
11. MligTC455_46768 270 5.62 Mlig455_058364

Neo: -

Age: -

WDR49 2.484 - 0.742 0.957 - 0.785 - Mlig455_058364 {REF} {Length: 4549} {Pfam: WD domain, G-beta repeat [PF00400.34, score=83.4]; EF-hand domain pair [PF13833.8, score=23.4]} {Human: ENSG00000174776, WDR49, WD repeat domain 49, [Score=695, Expect=0.0]} {Mouse: ENSMUSG00000104301, Wdr49, WD repeat domain 49, [Score=424, Expect=3e-134]} {Dmel: FBgn0023527, CG3071, [Score=57.8, Expect=4e-08]} {Smed: dd_Smed_v6_13248_0_8, dd_Smed_v6_13248_0_8, [Score=880, Expect=0.0]} {RNA1509_4168} {RNA1310_1044.1} {RNA815_1801}
12. MligTC455_41326 407 8.48 Mlig455_011060

Neo: -

Age: -

KCNA2 2.465 0.712 - 0.950 - 0.803 - Mlig455_011060 {REF} {Length: 6096} {Pfam: Ion transport protein [PF00520.33, score=161.6]; BTB/POZ domain [PF02214.24, score=99.2]; Ion channel [PF07885.18, score=50.3]} {Human: ENSG00000177301, KCNA2, potassium voltage-gated channel subfamily A member 2, [RH, Score=620, Expect=0.0]; ENSG00000111262, KCNA1, potassium voltage-gated channel subfamily A member 1, [RH, Score=617, Expect=0.0]; ENSG00000177272, KCNA3, potassium voltage-gated channel subfamily A member 3, [RH, Score=611, Expect=0.0]} {Mouse: ENSMUSG00000040724, Kcna2, potassium voltage-gated channel, shaker-related subfamily, member 2, [RH, Score=619, Expect=0.0]; ENSMUSG00000047976, Kcna1, potassium voltage-gated channel, shaker-related subfamily, member 1, [RH, Score=617, Expect=0.0]; ENSMUSG00000047959, Kcna3, potassium voltage-gated channel, shaker-related subfamily, member 3, [RH, Score=607, Expect=0.0]} {Dmel: FBgn0003380, Sh, Shaker, [RH, Score=643, Expect=0.0]} {Celegans: WBGene00014261, shk-1, Potassium voltage-gated channel protein shk-1, [RH, Score=383, Expect=6e-127]} {Smed: dd_Smed_v6_15425_0_1, dd_Smed_v6_15425_0_1, [RH, Score=715, Expect=0.0]} {RNA1509_19798} {RNA1310_8877, RNA1509_19798} {RNA1509_19798, RNA815_8082.1}
13. MligTC455_46584 107 2.22 Mlig455_010128

Neo: -

Age: Up-Down-Down

KCNC2 2.441 0.759 - 0.951 - 0.731 - Mlig455_010128 {REF} {Length: 1706} {Human: ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=74.3, Expect=3e-15]} {Mouse: ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=74.3, Expect=3e-16]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=114, Expect=3e-29]} {Celegans: WBGene00001202, egl-36, Potassium voltage-gated channel protein egl-36, [Score=100, Expect=1e-24]} {Smed: dd_Smed_v6_17998_0_1, dd_Smed_v6_17998_0_1, [Score=118, Expect=1e-32]} {RNA1310_24374} {RNA815_11270}
14. MligTC455_43375 367 7.65 Mlig455_003848

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.356

COL24A1 1.86 - - 0.894 - 0.966 - Mlig455_003848 {REF} {Length: 4716} {Pfam: Collagen triple helix repeat (20 copies) [PF01391.20, score=496.0]; Fibrillar collagen C-terminal domain [PF01410.20, score=111.2]} {Human: ENSG00000171502, COL24A1, collagen type XXIV alpha 1 chain, [Score=371, Expect=1e-105]} {Mouse: ENSMUSG00000029661, Col1a2, collagen, type I, alpha 2, [RH, Score=378, Expect=2e-109]} {Dmel: FBgn0000299, Col4a1, Collagen type IV alpha 1, [Score=343, Expect=2e-96]} {Celegans: WBGene00001263, emb-9, Collagen alpha-1(IV) chain, [Score=291, Expect=4e-80]} {Smed: dd_Smed_v6_8075_0_1, dd_Smed_v6_8075_0_1, [Score=478, Expect=2e-144]} {RNA1509_4709} {RNA1310_1394, RNA1509_4709} {RNA1509_4709, RNA815_513}
15. MligTC455_16806 674 14.05 Mlig455_035157

Neo: -

Age: logFC(26M/2M)=-0.346

Region-enriched R2: 3.343/0.00027
Region-enriched R3: 2.806/0.00113

1.847 - - - - 0.958 0.889 Mlig455_035157 {REF} {Length: 2225} {RNA1509_29674, RNA1509_7880} {RNA1310_2112, RNA1509_29674, RNA1509_7880} {RNA1509_29674, RNA1509_7880, RNA815_5601}
16. MligTC455_46419 3450 71.87 Mlig455_001787

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.331

ABCB1 1.838 - 0.860 - 0.978 - - Mlig455_001787 {REF} {Length: 5707} {TRANSSPLICED} {Pfam: ABC transporter transmembrane region [PF00664.25, score=438.9]; ABC transporter [PF00005.29, score=256.7]; RecF/RecN/SMC N terminal domain [PF02463.21, score=62.1]; AAA ATPase domain [PF13191.8, score=39.3]; AAA domain [PF13401.8, score=33.4]; Predicted ATPase of the ABC class [PF09818.11, score=30.8]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=30.2]; Zeta toxin [PF06414.14, score=27.1]; P-loop containing region of AAA domain [PF13555.8, score=26.2]; AAA domain [PF13604.8, score=24.8]; RsgA GTPase [PF03193.18, score=24.4]; AAA domain (dynein-related subfamily) [PF07728.16, score=24.4]; Rad17 P-loop domain [PF03215.17, score=23.1]; Adenylylsulphate kinase [PF01583.22, score=22.7]; AAA domain [PF13238.8, score=20.8]; Protein of unknown function (DUF815) [PF05673.15, score=19.9]; Putative exonuclease SbcCD, C subunit [PF13558.8, score=19.2]; Phosphoribulokinase / Uridine kinase family [PF00485.20, score=18.8]; ATP synthase alpha/beta family, nucleotide-binding domain [PF00006.27, score=18.7]} {Human: ENSG00000085563, ABCB1, ATP binding cassette subfamily B member 1, [RH, Score=1188, Expect=0.0]; ENSG00000005471, ABCB4, ATP binding cassette subfamily B member 4, [RH, Score=1144, Expect=0.0]} {Mouse: ENSMUSG00000028970, Abcb1b, ATP-binding cassette, sub-family B (MDR/TAP), member 1B, [RH, Score=1180, Expect=0.0]; ENSMUSG00000040584, Abcb1a, ATP-binding cassette, sub-family B (MDR/TAP), member 1A, [RH, Score=1176, Expect=0.0]; ENSMUSG00000042476, Abcb4, ATP-binding cassette, sub-family B (MDR/TAP), member 4, [RH, Score=1139, Expect=0.0]} {Dmel: FBgn0010241, Mdr50, Multi drug resistance 50, [RH, Score=894, Expect=0.0]} {Celegans: WBGene00004003, pgp-9, P-GlycoProtein related, [RH, Score=1137, Expect=0.0]} {Smed: dd_Smed_v6_4124_0_1, dd_Smed_v6_4124_0_1, [RH, Score=1009, Expect=0.0]} {RNA1509_1034, RNA1509_43495, RNA1509_48254} {RNA1310_1064, RNA1509_43495, RNA1509_48254} {RNA1509_43495, RNA1509_48254, RNA815_387.1}
17. MligTC455_33198 253 5.26 Mlig455_062515

Neo: Irradiation

Age: Up-Down-Down, logFC(26M/2M)=-0.392

CAMKK2 1.824 - - 0.962 - 0.862 - Mlig455_062515 {REF} {Length: 3912} {Pfam: Protein kinase domain [PF00069.27, score=207.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=120.0]; Kinase-like [PF14531.8, score=29.6]} {Human: ENSG00000110931, CAMKK2, calcium/calmodulin dependent protein kinase kinase 2, [RH, Score=418, Expect=3e-134]; ENSG00000004660, CAMKK1, calcium/calmodulin dependent protein kinase kinase 1, [RH, Score=399, Expect=3e-127]} {Mouse: ENSMUSG00000029471, Camkk2, calcium/calmodulin-dependent protein kinase kinase 2, beta, [RH, Score=409, Expect=9e-131]; ENSMUSG00000020785, Camkk1, calcium/calmodulin-dependent protein kinase kinase 1, alpha, [RH, Score=395, Expect=5e-126]} {Dmel: FBgn0040056, CG17698, [RH, Score=404, Expect=1e-127]} {Celegans: WBGene00000518, ckk-1, Calcium/calmodulin-dependent protein kinase kinase, [RH, Score=415, Expect=1e-133]} {Smed: dd_Smed_v6_18437_0_1, dd_Smed_v6_18437_0_1, [RH, Score=367, Expect=1e-114]} {RNA1509_51718} {RNA1310_7593.1} {RNA815_7566}
18. MligTC455_33199 144 3 Mlig455_068562

Neo: -

Age: -

CAMKK2 1.822 - - 0.950 - 0.872 - Mlig455_068562 {REF} {Length: 3078} {Pfam: Protein kinase domain [PF00069.27, score=209.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=121.7]; Kinase-like [PF14531.8, score=30.4]; Fungal protein kinase [PF17667.3, score=19.0]} {Human: ENSG00000110931, CAMKK2, calcium/calmodulin dependent protein kinase kinase 2, [RH, Score=417, Expect=4e-138]} {Mouse: ENSMUSG00000029471, Camkk2, calcium/calmodulin-dependent protein kinase kinase 2, beta, [RH, Score=409, Expect=4e-135]; ENSMUSG00000020785, Camkk1, calcium/calmodulin-dependent protein kinase kinase 1, alpha, [RH, Score=394, Expect=1e-129]} {Dmel: FBgn0040056, CG17698, [RH, Score=402, Expect=1e-130]} {Celegans: WBGene00000518, ckk-1, Calcium/calmodulin-dependent protein kinase kinase, [RH, Score=414, Expect=3e-137]} {Smed: dd_Smed_v6_18437_0_1, dd_Smed_v6_18437_0_1, [RH, Score=367, Expect=3e-118]} {RNA1509_51718} {RNA1310_7593.1} {RNA815_7566}
19. MligTC455_53626 1548 32.26 Mlig455_066093

Neo: -

Age: -

SLC11A2 1.81 - - 0.978 - 0.832 - Mlig455_066093 {REF} {Length: 2925} {TRANSSPLICED} {Pfam: Natural resistance-associated macrophage protein [PF01566.20, score=275.3]} {Human: ENSG00000110911, SLC11A2, solute carrier family 11 member 2, [Score=426, Expect=1e-144]} {Mouse: ENSMUSG00000023030, Slc11a2, solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2, [Score=438, Expect=7e-150]} {Dmel: FBgn0011672, Mvl, Malvolio, [Score=385, Expect=8e-129]} {Celegans: WBGene00004876, smf-1, NRAMP-like transporter smf-1, [Score=399, Expect=2e-134]} {Smed: dd_Smed_v6_4739_0_1, dd_Smed_v6_4739_0_1, [Score=471, Expect=2e-163]} {RNA1509_4177, RNA1509_42719, RNA1509_53413} {RNA1310_2767.1, RNA1509_42719, RNA1509_53413} {RNA1509_42719, RNA1509_53413, RNA815_3248}
20. MligTC455_53512 916 19.08 Mlig455_028726

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.315

Region-enriched R2: 1.504/0.01018

IFT172 1.796 - - - 0.839 0.957 - Mlig455_028726 {REF} {Length: 2813} {Pfam: Region in Clathrin and VPS [PF00637.22, score=23.3]; Tetratricopeptide repeat [PF13176.8, score=19.3]} {Human: ENSG00000138002, IFT172, intraflagellar transport 172, [Score=871, Expect=0.0]} {Mouse: ENSMUSG00000038564, Ift172, intraflagellar transport 172, [Score=873, Expect=0.0]} {Dmel: FBgn0035317, Oseg2, Outer segment 2, [Score=546, Expect=5e-173]} {Celegans: WBGene00003883, osm-1, Intraflagellar transport protein osm-1, [Score=517, Expect=2e-162]} {Smed: dd_Smed_v6_10638_0_1, dd_Smed_v6_10638_0_1, [Score=615, Expect=0.0]} {RNA1509_2378} {RNA1310_994} {RNA815_250}
21. MligTC455_45466 2676 55.75 Mlig455_022860, Mlig455_044320

Neo: -

Age: logFC(26M/2M)=3.216

1.785 - - - 0.950 - 0.835

Mlig455_022860 {REF} {Length: 1595} {RNA1509_57288} {RNA1310_30305} {RNA815_10549}

Mlig455_044320 {REF} {Length: 1566} {RNA1509_57288} {RNA1310_30931, RNA1509_57288} {RNA1509_57288, RNA815_10549}
22. MligTC455_49690 72 1.5 Mlig455_068367

Neo: -

Age: Down-Down-Up

1.781 - - 0.961 - 0.820 - Mlig455_068367 {REF} {Length: 1546} {Smed: dd_Smed_v6_8297_0_1, dd_Smed_v6_8297_0_1, [RH, Score=53.1, Expect=2e-09]} {RNA1509_38073} {RNA1310_34998} {RNA815_20391}
23. MligTC455_31470 1339 27.91 Mlig455_002685

Neo: -

Age: logFC(26M/2M)=-0.799

CCDC189 1.769 - 0.805 - 0.964 - - Mlig455_002685 {REF} {Length: 1248} {Pfam: Flagellar C1a complex subunit C1a-32 [PF14769.8, score=115.2]} {Human: ENSG00000196118, CCDC189, coiled-coil domain containing 189, [RH, Score=129, Expect=1e-34]} {Mouse: ENSMUSG00000057176, Ccdc189, coiled-coil domain containing 189, [Score=133, Expect=3e-36]} {Smed: dd_Smed_v6_12703_0_1, dd_Smed_v6_12703_0_1, [RH, Score=162, Expect=4e-48]} {RNA1509_7747} {RNA1310_28715} {RNA815_12270.1}
24. MligTC455_34365 761 15.86 Mlig455_045898

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-1.155

1.76 - 0.809 - - 0.951 - Mlig455_045898 {REF} {Length: 1534} {RNA1509_18388, RNA1509_36026, RNA1509_43852} {RNA1310_33460, RNA1509_18388, RNA1509_36026, RNA1509_43852} {RNA1509_18388, RNA1509_36026, RNA1509_43852, RNA815_35266}
25. MligTC455_51779 660 13.75 Mlig455_031396

Neo: -

Age: Up-Down-Down

Region-enriched R2: 2.441/0.00016

CACNA1C 1.759 - - 0.950 - 0.809 - Mlig455_031396 {REF} {Length: 8157} {Pfam: Ion transport protein [PF00520.33, score=797.6]; Voltage gated calcium channel IQ domain [PF08763.13, score=101.0]; Voltage-dependent L-type calcium channel, IQ-associated [PF16905.7, score=100.3]; Polycystin cation channel [PF08016.14, score=31.5]} {Human: ENSG00000151067, CACNA1C, calcium voltage-gated channel subunit alpha1 C, [Score=1289, Expect=0.0]; ENSG00000285479, CACNA1C, calcium voltage-gated channel subunit alpha1 C, [Score=1289, Expect=0.0]; ENSG00000157388, CACNA1D, calcium voltage-gated channel subunit alpha1 D, [Score=1286, Expect=0.0]; ENSG00000081248, CACNA1S, calcium voltage-gated channel subunit alpha1 S, [Score=1273, Expect=0.0]} {Mouse: ENSMUSG00000051331, Cacna1c, calcium channel, voltage-dependent, L type, alpha 1C subunit, [Score=1294, Expect=0.0]; ENSMUSG00000015968, Cacna1d, calcium channel, voltage-dependent, L type, alpha 1D subunit, [Score=1288, Expect=0.0]; ENSMUSG00000031142, Cacna1f, calcium channel, voltage-dependent, alpha 1F subunit, [Score=1276, Expect=0.0]; ENSMUSG00000026407, Cacna1s, calcium channel, voltage-dependent, L type, alpha 1S subunit, [Score=1260, Expect=0.0]} {Dmel: FBgn0001991, Ca-alpha1D, Ca[2+]-channel protein alpha[[1]] subunit D, [Score=1292, Expect=0.0]} {Celegans: WBGene00006742, unc-2, High voltage activated calcium channel alpha-1 subunit, [RH, Score=1690, Expect=0.0]} {Smed: dd_Smed_v6_13295_0_1, dd_Smed_v6_13295_0_1, [RH, Score=2129, Expect=0.0]} {RNA1509_11510} {RNA1310_2184.1} {RNA815_2606}
26. MligTC455_31805 747 15.56 Mlig455_070318

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.499

EFCAB6 1.758 - - 0.951 - 0.807 - Mlig455_070318 {REF} {Length: 3714} {Pfam: EF-hand domain pair [PF13499.8, score=82.4]; EF-hand domain [PF08976.13, score=72.0]; EF-hand domain pair [PF13833.8, score=64.0]; EF-hand domain [PF13405.8, score=56.9]; EF hand [PF00036.34, score=53.2]; EF-hand domain [PF14658.8, score=34.9]; Family of unknown function (DUF5580) [PF17743.3, score=27.9]; EF hand [PF13202.8, score=22.4]} {Human: ENSG00000186976, EFCAB6, EF-hand calcium binding domain 6, [Score=86.3, Expect=2e-16]} {Mouse: ENSMUSG00000022441, Efcab6, EF-hand calcium binding domain 6, [Score=76.6, Expect=1e-13]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=48.9, Expect=2e-06]} {Celegans: WBGene00017394, cal-8, CALmodulin related genes, [Score=50.8, Expect=4e-07]} {Smed: dd_Smed_v6_20435_0_1, dd_Smed_v6_20435_0_1, [Score=157, Expect=1e-40]} {RNA1509_7148} {RNA1310_3069.1} {RNA815_3758}
27. MligTC455_43733 869 18.1 Mlig455_034271, Mlig455_034309

Neo: -

Age: Down-Up-Up

1.751 - 0.801 0.950 - - -

Mlig455_034271 {REF} {Length: 2291} {Pfam: Protein kinase domain [PF00069.27, score=27.1]} {RNA1509_10827} {RNA1310_17438} {RNA815_7916}

Mlig455_034309 {REF} {Length: 2300} {RNA1509_10827} {RNA1310_9412} {RNA815_7916}
28. MligTC455_43734 871 18.15 Mlig455_067307, Mlig455_067323

Neo: -

Age: logFC(26M/2M)=-0.518

SIK3 1.751 - 0.800 0.951 - - -

Mlig455_067307 {REF} {Length: 3849} {Pfam: Protein kinase domain [PF00069.27, score=49.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=24.7]} {Human: ENSG00000160584, SIK3, SIK family kinase 3, [Score=71.6, Expect=3e-12]; ENSG00000007047, MARK4, microtubule affinity regulating kinase 4, [Score=70.5, Expect=5e-12]} {Mouse: ENSMUSG00000034135, Sik3, SIK family kinase 3, [Score=70.5, Expect=4e-12]; ENSMUSG00000030397, Mark4, MAP/microtubule affinity regulating kinase 4, [Score=70.1, Expect=5e-12]} {Dmel: FBgn0025625, Sik2, Salt-inducible kinase 2, [Score=61.6, Expect=2e-09]} {Celegans: WBGene00006814, unc-82, [Score=61.6, Expect=2e-09]} {Smed: dd_Smed_v6_5124_0_2, dd_Smed_v6_5124_0_2, [Score=68.6, Expect=8e-12]} {RNA1509_10827} {RNA1310_9412, RNA1509_10827} {RNA1509_10827, RNA815_7916}

Mlig455_067323 {REF} {Length: 2835} {Pfam: Protein kinase domain [PF00069.27, score=49.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=24.7]} {Human: ENSG00000160584, SIK3, SIK family kinase 3, [Score=71.6, Expect=3e-12]; ENSG00000007047, MARK4, microtubule affinity regulating kinase 4, [Score=70.5, Expect=5e-12]} {Mouse: ENSMUSG00000034135, Sik3, SIK family kinase 3, [Score=70.5, Expect=4e-12]; ENSMUSG00000030397, Mark4, MAP/microtubule affinity regulating kinase 4, [Score=70.1, Expect=5e-12]} {Dmel: FBgn0025625, Sik2, Salt-inducible kinase 2, [Score=61.6, Expect=2e-09]} {Celegans: WBGene00006814, unc-82, [Score=61.6, Expect=2e-09]} {Smed: dd_Smed_v6_5124_0_2, dd_Smed_v6_5124_0_2, [Score=68.6, Expect=8e-12]} {RNA1509_10827} {RNA1310_9412} {RNA815_7916}
29. MligTC455_37343 240 4.99 Mlig455_024086

Neo: -

Age: Up-Down-Up

Region-enriched R8: 2.659/0.04266

1.75 - - 0.958 - 0.792 - Mlig455_024086 {REF} {Length: 4209} {RNA1509_36528, RNA1509_59718} {RNA1310_12514, RNA1509_36528, RNA1509_59718} {RNA1509_36528, RNA1509_59718, RNA815_21020}
30. MligTC455_35174 342 7.13 Mlig455_009545, Mlig455_054086

Neo: -

Age: Up-Down-Down

PTPRN2 1.749 0.793 - 0.956 - - -

Mlig455_009545 {REF} {Length: 87} {NoTransDecoderORF} {RNA1509_3577} {RNA1310_173.2} {RNA815_26664}

Mlig455_054086 {REF} {Length: 10208} {Pfam: Protein-tyrosine phosphatase [PF00102.29, score=222.7]} {Human: ENSG00000155093, PTPRN2, protein tyrosine phosphatase, receptor type N2, [RH, Score=412, Expect=1e-129]} {Mouse: ENSMUSG00000056553, Ptprn2, protein tyrosine phosphatase, receptor type, N polypeptide 2, [RH, Score=407, Expect=7e-128]} {Dmel: FBgn0031294, IA-2, IA-2 protein tyrosine phosphatase, [RH, Score=376, Expect=8e-114]} {Celegans: WBGene00002048, ida-1, IA2; IDA-1 protein; Related to Islet cell Diabetes Autoantigen, [Score=280, Expect=1e-82]} {Smed: dd_Smed_v6_6990_0_1, dd_Smed_v6_6990_0_1, [RH, Score=391, Expect=8e-125]} {RNA1509_34721, RNA1509_41198} {RNA1310_3634, RNA1509_34721, RNA1509_41198} {RNA1509_34721, RNA1509_41198, RNA815_1727.1}
31. MligTC455_37342 203 4.23 Mlig455_024018

Neo: -

Age: -

1.745 - - 0.953 - 0.792 - Mlig455_024018 {REF} {Length: 1374} {RNA1509_59718} {RNA1310_33285} {RNA815_22262}
32. MligTC455_39663 257 5.36 Mlig455_035826

Neo: -

Age: -

Region-enriched R2: 2.079/0.03628

ERG 1.741 - 0.783 0.958 - - - Mlig455_035826 {REF} {Length: 1844} {Pfam: Ets-domain [PF00178.24, score=118.3]} {Human: ENSG00000157554, ERG, ERG, ETS transcription factor, [RH, Score=206, Expect=1e-62]; ENSG00000151702, FLI1, Fli-1 proto-oncogene, ETS transcription factor, [RH, Score=200, Expect=1e-62]} {Mouse: ENSMUSG00000040732, Erg, ETS transcription factor, [RH, Score=204, Expect=2e-62]; ENSMUSG00000016087, Fli1, Friend leukemia integration 1, [RH, Score=200, Expect=2e-60]} {Dmel: FBgn0005658, Ets65A, Ets at 65A, [RH, Score=211, Expect=3e-67]} {Celegans: WBGene00020368, ast-1, Axon STeering defect, [RH, Score=185, Expect=5e-56]} {Smed: dd_Smed_v6_11113_0_1, dd_Smed_v6_11113_0_1, [RH, Score=237, Expect=2e-76]} {RNA1509_29423} {RNA1310_27275.1, RNA1509_29423} {RNA1509_29423, RNA815_13091}
33. MligTC455_41942 3252 67.74 Mlig455_030861

Neo: -

Age: -

MAD1L1 1.74 - - 0.783 0.957 - - Mlig455_030861 {REF} {Length: 3718} {TRANSSPLICED} {Pfam: Mitotic checkpoint protein [PF05557.15, score=130.8]} {Human: ENSG00000002822, MAD1L1, mitotic arrest deficient 1 like 1, [RH, Score=92.8, Expect=1e-18]} {Dmel: FBgn0026326, Mad1, Mitotic arrest-deficient 1, [RH, Score=65.5, Expect=2e-10]} {RNA1509_21631} {RNA1310_5312} {RNA815_1674}
34. MligTC455_42863 4143 86.31 Mlig455_015957

Neo: -

Age: -

CCDC65 1.724 - - - - 0.968 0.756 Mlig455_015957 {REF} {Length: 1928} {TRANSSPLICED} {Pfam: Sperm tail [PF14772.8, score=82.2]; Sperm tail C-terminal domain [PF14775.8, score=25.0]} {Human: ENSG00000139537, CCDC65, coiled-coil domain containing 65, [RH, Score=401, Expect=3e-135]} {Mouse: ENSMUSG00000003354, Ccdc65, coiled-coil domain containing 65, [RH, Score=420, Expect=1e-142]} {Dmel: FBgn0050259, CG30259, [RH, Score=166, Expect=8e-45]} {Smed: dd_Smed_v6_6152_0_1, dd_Smed_v6_6152_0_1, [RH, Score=525, Expect=0.0]} {RNA1509_10456, RNA1509_14724, RNA1509_1709, RNA1509_21982, RNA1509_37196} {RNA1310_14593, RNA1509_10456, RNA1509_14724, RNA1509_1709, RNA1509_21982, RNA1509_37196} {RNA1509_10456, RNA1509_14724, RNA1509_1709, RNA1509_21982, RNA1509_37196, RNA815_5330}
35. MligTC455_04162 131 2.73 Mlig455_028924

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.575

HMCN1 1.721 0.771 - 0.950 - - - Mlig455_028924 {REF} {Length: 3929} {Pfam: Immunoglobulin domain [PF13927.8, score=144.9]; Immunoglobulin I-set domain [PF07679.18, score=119.8]; Immunoglobulin domain [PF13895.8, score=113.4]; Immunoglobulin domain [PF00047.27, score=102.3]; Immunoglobulin V-set domain [PF07686.19, score=36.7]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=35.3]; Immunoglobulin C1-set domain [PF07654.17, score=23.3]; C17orf99 Ig domain [PF17736.3, score=20.9]; Immunoglobulin domain [PF18452.3, score=19.8]} {Human: ENSG00000143341, HMCN1, hemicentin 1, [Score=103, Expect=2e-21]; ENSG00000148357, HMCN2, hemicentin 2, [Score=100, Expect=8e-21]} {Mouse: ENSMUSG00000051747, Ttn, titin, [Score=107, Expect=5e-23]; ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=103, Expect=7e-22]} {Dmel: FBgn0000547, ed, echinoid, [Score=147, Expect=2e-35]} {Celegans: WBGene00001863, him-4, Hemicentin; High Incidence of Males (Increased X chromosome loss), [Score=100, Expect=3e-21]} {Smed: dd_Smed_v6_13903_0_1, dd_Smed_v6_13903_0_1, [Score=162, Expect=2e-40]} {RNA1310_26618} {RNA815_41641}
36. MligTC455_51306 600 12.49 Mlig455_031984

Neo: -

Age: logFC(26M/2M)=-0.521

DCTN1 1.703 - 0.746 - - 0.957 - Mlig455_031984 {REF} {Length: 3800} {TRANSSPLICED} {Pfam: CAP-Gly domain [PF01302.27, score=63.6]} {Human: ENSG00000204843, DCTN1, dynactin subunit 1, [Score=56.6, Expect=2e-07]; ENSG00000106665, CLIP2, CAP-Gly domain containing linker protein 2, [Score=56.2, Expect=3e-07]; ENSG00000197892, KIF13B, kinesin family member 13B, [Score=55.8, Expect=3e-07]} {Mouse: ENSMUSG00000031865, Dctn1, dynactin 1, [Score=57.8, Expect=7e-09]} {Dmel: FBgn0033055, Tbce, Tubulin-specific chaperone E, [Score=64.3, Expect=3e-10]} {Smed: dd_Smed_v6_12415_0_2, dd_Smed_v6_12415_0_2, [Score=99.0, Expect=3e-21]} {RNA1509_15825} {RNA1310_31448.1} {RNA815_3703.1}
37. MligTC455_43836 2273 47.36 Mlig455_056036, Mlig455_057471

Neo: -

Age: logFC(26M/2M)=-0.376

1.701 - 0.744 - - 0.957 -

Mlig455_056036 {REF} {Length: 2867} {RNA1509_28671} {RNA1310_6148} {RNA815_2070.1}

Mlig455_057471 {REF} {Length: 2932} {RNA1509_27859, RNA1509_28671, RNA1509_41523, RNA1509_5876} {RNA1310_6148, RNA1509_27859, RNA1509_28671, RNA1509_41523, RNA1509_5876} {RNA1509_27859, RNA1509_28671, RNA1509_41523, RNA1509_5876, RNA815_2070.1}
38. MligTC455_49635 2917 60.78 Mlig455_021335

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.377

LRTOMT 1.693 - - - 0.735 - 0.958 Mlig455_021335 {REF} {Length: 944} {Pfam: Leucine Rich repeats (2 copies) [PF12799.9, score=44.2]; Leucine-rich repeat [PF14580.8, score=43.9]; Leucine rich repeat [PF13855.8, score=36.8]} {Human: ENSG00000184154, LRTOMT, leucine rich transmembrane and O-methyltransferase domain containing, [RH, Score=145, Expect=4e-43]} {Mouse: ENSMUSG00000064307, Lrrc51, leucine rich repeat containing 51, [RH, Score=149, Expect=6e-45]} {Celegans: WBGene00003390, mog-2, Probable U2 small nuclear ribonucleoprotein A', [Score=59.3, Expect=2e-10]} {Smed: dd_Smed_v6_8583_0_1, dd_Smed_v6_8583_0_1, [RH, Score=170, Expect=4e-53]} {RNA1509_7051} {RNA1310_42278, RNA1509_7051} {RNA1509_7051, RNA815_19576}
39. MligTC455_52286 301 6.27 Mlig455_051314

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.320

AGO2 1.68 - - 0.962 - - 0.718 Mlig455_051314 {REF} {Length: 4274} {Pfam: Piwi domain [PF02171.19, score=369.3]; Mid domain of argonaute [PF16487.7, score=114.6]; N-terminal domain of argonaute [PF16486.7, score=104.8]; PAZ domain [PF02170.24, score=82.1]; Argonaute linker 1 domain [PF08699.12, score=78.7]; Argonaute linker 2 domain [PF16488.7, score=48.4]} {Human: ENSG00000123908, AGO2, argonaute 2, RISC catalytic component, [RH, Score=1254, Expect=0.0]; ENSG00000092847, AGO1, argonaute 1, RISC catalytic component, [RH, Score=1230, Expect=0.0]; ENSG00000126070, AGO3, argonaute 3, RISC catalytic component, [RH, Score=1222, Expect=0.0]; ENSG00000134698, AGO4, argonaute 4, RISC catalytic component, [RH, Score=1199, Expect=0.0]} {Mouse: ENSMUSG00000036698, Ago2, argonaute RISC catalytic subunit 2, [RH, Score=1258, Expect=0.0]; ENSMUSG00000041530, Ago1, argonaute RISC catalytic subunit 1, [RH, Score=1230, Expect=0.0]; ENSMUSG00000028842, Ago3, argonaute RISC catalytic subunit 3, [RH, Score=1221, Expect=0.0]} {Dmel: FBgn0262739, AGO1, Argonaute-1, [RH, Score=1342, Expect=0.0]} {Celegans: WBGene00000105, alg-1, Argonaute-like, [RH, Score=1260, Expect=0.0]} {Smed: dd_Smed_v6_3861_0_1, dd_Smed_v6_3861_0_1, [RH, Score=1449, Expect=0.0]} {RNA1509_3358} {RNA1310_4477.1, RNA1509_3358} {RNA1509_3358, RNA815_1509.1}
40. MligTC455_45969 1220 25.42 Mlig455_045083

Neo: -

Age: -

1.668 - - - 0.715 0.953 - Mlig455_045083 {REF} {Length: 2063} {TRANSSPLICED} {RNA1509_16069, RNA1509_41818, RNA1509_49053, RNA1509_56846} {RNA1310_17143, RNA1509_41818, RNA1509_49053, RNA1509_56846} {RNA1509_41818, RNA1509_49053, RNA1509_56846, RNA815_14588}
41. MligTC455_53608 2624 54.66 Mlig455_066346

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=2.900

SPAG6 1.667 - - 0.952 - 0.715 - Mlig455_066346 {REF} {Length: 1967} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=130.5]; HEAT repeats [PF13646.8, score=55.3]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=52.1]; HEAT repeat [PF02985.24, score=50.8]; HEAT-like repeat [PF13513.8, score=35.3]; Adaptin N terminal region [PF01602.22, score=31.7]; C-terminal domain of two-partite extracellular sensor domain [PF17150.6, score=31.5]; DNA alkylation repair enzyme [PF08713.13, score=30.7]; Proteasome non-ATPase 26S subunit [PF10508.11, score=24.4]; Rapamycin-insensitive companion of mTOR, N-term [PF14664.8, score=19.6]} {Human: ENSG00000077327, SPAG6, sperm associated antigen 6, [RH, Score=863, Expect=0.0]} {Mouse: ENSMUSG00000022783, Spag6l, sperm associated antigen 6-like, [RH, Score=881, Expect=0.0]} {Dmel: FBgn0024889, Kap-alpha1, karyopherin alpha1, [Score=65.5, Expect=5e-11]} {Celegans: WBGene00002074, ima-3, Importin subunit alpha-3, [Score=70.9, Expect=8e-13]} {Smed: dd_Smed_v6_3991_0_1, dd_Smed_v6_3991_0_1, [RH, Score=894, Expect=0.0]} {RNA1509_1649} {RNA1310_12357} {RNA815_5582.1}
42. MligTC455_47704 106 2.21 Mlig455_032247

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.432

WSCD2 1.657 - - 0.951 - 0.706 - Mlig455_032247 {REF} {Length: 2305} {Pfam: WSC domain [PF01822.21, score=58.4]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=54.7, Expect=1e-07]; ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=52.8, Expect=5e-07]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=56.6, Expect=3e-08]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=63.9, Expect=1e-10]} {RNA1509_59284} {RNA1310_13567} {RNA815_27780}
43. MligTC455_30234 668 13.92 Mlig455_013688, Mlig455_020164, Mlig455_028077, Mlig455_036489, Mlig455_038238, Mlig455_049777, Mlig455_054410, Mlig455_055118, Mlig455_061417, Mlig455_068974, Mlig455_070511

Neo: -

Age: Up-Down-Down

PIF1 1.654 - - 0.953 - 0.701 -

Mlig455_013688 {REF} {Length: 3931} {Pfam: PIF1-like helicase [PF05970.16, score=335.0]; AAA domain [PF13604.8, score=47.7]; UvrD-like helicase C-terminal domain [PF13538.8, score=26.1]; AAA domain [PF13245.8, score=19.3]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=125, Expect=6e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=120, Expect=1e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=124, Expect=4e-29]} {Celegans: WBGene00019136, F59H6.5, [Score=479, Expect=1e-149]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=5e-27]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_020164 {REF} {Length: 6683} {Pfam: PIF1-like helicase [PF05970.16, score=335.2]; AAA domain [PF13604.8, score=47.8]; UvrD-like helicase C-terminal domain [PF13538.8, score=26.2]; AAA domain [PF13245.8, score=19.4]; Helicase [PF02689.16, score=16.6]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=125, Expect=6e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=120, Expect=2e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=124, Expect=3e-29]} {Celegans: WBGene00019136, F59H6.5, [Score=479, Expect=5e-150]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=4e-27]} {RNA1509_5036} {RNA1310_6950, RNA1509_5036} {RNA1509_5036, RNA815_356.1}

Mlig455_028077 {REF} {Length: 5927} {TRANSSPLICED} {Pfam: PIF1-like helicase [PF05970.16, score=333.5]; Helitron helicase-like domain at N-terminus [PF14214.8, score=174.6]; AAA domain [PF13604.8, score=45.8]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.1]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=126, Expect=1e-28]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=121, Expect=2e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=123, Expect=3e-28]} {Celegans: WBGene00021577, Y46B2A.2, [RH, Score=737, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=2e-26]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_036489 {REF} {Length: 6279} {TRANSSPLICED} {Pfam: PIF1-like helicase [PF05970.16, score=335.1]; AAA domain [PF13604.8, score=47.6]; UvrD-like helicase C-terminal domain [PF13538.8, score=26.1]; AAA domain [PF13245.8, score=19.3]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=125, Expect=6e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=120, Expect=1e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=124, Expect=6e-29]} {Celegans: WBGene00019136, F59H6.5, [Score=509, Expect=7e-161]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=4e-27]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_038238 {REF} {Length: 7170} {Pfam: PIF1-like helicase [PF05970.16, score=335.2]; Helitron helicase-like domain at N-terminus [PF14214.8, score=174.3]; AAA domain [PF13604.8, score=44.8]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.2]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=126, Expect=8e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=122, Expect=8e-28]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=121, Expect=1e-27]} {Celegans: WBGene00021577, Y46B2A.2, [RH, Score=736, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=2e-26]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_049777 {REF} {Length: 6866} {Pfam: PIF1-like helicase [PF05970.16, score=333.8]; Helitron helicase-like domain at N-terminus [PF14214.8, score=175.0]; AAA domain [PF13604.8, score=43.6]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.3]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=123, Expect=8e-28]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=117, Expect=2e-26]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=120, Expect=2e-27]} {Celegans: WBGene00019136, F59H6.5, [Score=760, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=1e-26]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_054410 {REF} {Length: 3239} {Pfam: Helitron helicase-like domain at N-terminus [PF14214.8, score=52.6]} {Celegans: WBGene00022692, ZK250.9, [Score=162, Expect=8e-44]} {Smed: dd_Smed_v6_91935_0_1, dd_Smed_v6_91935_0_1, [Score=45.1, Expect=8e-06]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_055118 {REF} {Length: 6779} {Pfam: PIF1-like helicase [PF05970.16, score=330.1]; Helitron helicase-like domain at N-terminus [PF14214.8, score=169.5]; AAA domain [PF13604.8, score=47.3]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.6]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=125, Expect=1e-28]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=122, Expect=5e-28]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=118, Expect=7e-27]} {Celegans: WBGene00018020, F33H12.6, [Score=733, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=113, Expect=2e-25]} {RNA1509_5036} {RNA1310_6950} {RNA815_356.1}

Mlig455_061417 {REF} {Length: 5410} {Pfam: Helitron helicase-like domain at N-terminus [PF14214.8, score=169.0]; PIF1-like helicase [PF05970.16, score=56.8]; AAA domain [PF13604.8, score=20.6]} {Celegans: WBGene00019136, F59H6.5, [Score=540, Expect=1e-169]} {Smed: dd_Smed_v6_91935_0_1, dd_Smed_v6_91935_0_1, [Score=70.5, Expect=4e-14]} {RNA1509_5036} {RNA1310_11485} {RNA815_356.1}

Mlig455_068974 {REF} {Length: 6598} {Pfam: PIF1-like helicase [PF05970.16, score=333.8]; Helitron helicase-like domain at N-terminus [PF14214.8, score=174.8]; AAA domain [PF13604.8, score=46.0]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.3]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=127, Expect=5e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=120, Expect=3e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=123, Expect=2e-28]} {Celegans: WBGene00019136, F59H6.5, [RH, Score=771, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=2e-26]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_070511 {REF} {Length: 6556} {Pfam: PIF1-like helicase [PF05970.16, score=335.6]; AAA domain [PF13604.8, score=48.1]; UvrD-like helicase C-terminal domain [PF13538.8, score=26.5]; AAA domain [PF13245.8, score=19.7]; Helicase [PF02689.16, score=16.9]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=125, Expect=4e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=119, Expect=1e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=124, Expect=4e-29]} {Celegans: WBGene00019136, F59H6.5, [Score=391, Expect=6e-119]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=3e-27]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}
44. MligTC455_40866 903 18.81 Mlig455_069160

Neo: -

Age: logFC(26M/2M)=-0.319

PDE4C 0.977 - - 0.977 - - - Mlig455_069160 {REF} {Length: 3308} {Pfam: 3'5'-cyclic nucleotide phosphodiesterase [PF00233.21, score=301.1]; Phosphodiesterase 4 upstream conserved regions (UCR) [PF18100.3, score=103.8]} {Human: ENSG00000105650, PDE4C, phosphodiesterase 4C, [RH, Score=545, Expect=0.0]; ENSG00000285188, AC008397.2, phosphodiesterase 4C, [RH, Score=545, Expect=0.0]; ENSG00000065989, PDE4A, phosphodiesterase 4A, [RH, Score=529, Expect=1e-174]} {Mouse: ENSMUSG00000111773, Pde4c, phosphodiesterase 4C, cAMP specific, [RH, Score=546, Expect=0.0]; ENSMUSG00000031842, Pde4c, phosphodiesterase 4C, cAMP specific, [RH, Score=546, Expect=0.0]; ENSMUSG00000032177, Pde4a, phosphodiesterase 4A, cAMP specific, [RH, Score=525, Expect=2e-173]} {Dmel: FBgn0000479, dnc, dunce, [Score=560, Expect=0.0]} {Celegans: WBGene00020114, pde-4, Probable 3',5'-cyclic phosphodiesterase pde-4, [RH, Score=506, Expect=2e-169]} {Smed: dd_Smed_v6_7735_0_1, dd_Smed_v6_7735_0_1, [Score=525, Expect=9e-176]} {RNA1509_8826} {RNA1310_493.1} {RNA815_3250}
45. MligTC455_40052 513 10.68 Mlig455_035856

Neo: -

Age: -

0.976 - - - - 0.976 - Mlig455_035856 {REF} {Length: 3180} {TRANSSPLICED} {Smed: dd_Smed_v6_14291_0_1, dd_Smed_v6_14291_0_1, [RH, Score=221, Expect=3e-61]} {RNA1509_6964} {RNA1310_5805} {RNA815_1720}
46. MligTC455_36854 480 10.01 Mlig455_043380, Mlig455_066320

Neo: -

Age: -

CCDC191 0.975 - - 0.975 - - -

Mlig455_043380 {REF} {Length: 4131} {TRANSSPLICED} {Human: ENSG00000163617, CCDC191, coiled-coil domain containing 191, [Score=115, Expect=2e-25]} {Mouse: ENSMUSG00000022701, Ccdc191, coiled-coil domain containing 191, [RH, Score=95.1, Expect=2e-19]} {Dmel: FBgn0031496, CG17258, [RH, Score=57.8, Expect=5e-08]} {Smed: dd_Smed_v6_8967_0_2, dd_Smed_v6_8967_0_2, [Score=132, Expect=2e-31]} {RNA1509_39248} {RNA1310_1501.1} {RNA815_1513}

Mlig455_066320 {REF} {Length: 4152} {TRANSSPLICED} {Human: ENSG00000163617, CCDC191, coiled-coil domain containing 191, [Score=149, Expect=2e-36]} {Mouse: ENSMUSG00000022701, Ccdc191, coiled-coil domain containing 191, [RH, Score=95.1, Expect=2e-19]} {Dmel: FBgn0031496, CG17258, [RH, Score=57.4, Expect=6e-08]} {Smed: dd_Smed_v6_8967_0_2, dd_Smed_v6_8967_0_2, [Score=138, Expect=3e-33]} {RNA1509_39248} {RNA1310_1501.1, RNA1509_39248} {RNA1509_39248, RNA815_1513}
47. MligTC455_14387 463 9.64 Mlig455_022195

Neo: -

Age: -

0.972 - - 0.972 - - - Mlig455_022195 {REF} {Length: 2088} {NoTransDecoderORF} {RNA1509_22930} {RNA1310_28859} {RNA815_13691}
48. MligTC455_21952 382 7.96 Mlig455_030974, Mlig455_069449

Neo: -

Age: Down-Up-Down

0.968 - - - - 0.968 -

Mlig455_030974 {REF} {Length: 5703} {Pfam: Tetratricopeptide repeat [PF07719.19, score=37.1]; Tetratricopeptide repeat [PF13428.8, score=32.3]; Tetratricopeptide repeat [PF14559.8, score=28.6]; Tetratricopeptide repeat [PF13181.8, score=27.7]; Tetratricopeptide repeat [PF00515.30, score=23.8]; Tetratricopeptide repeat [PF13176.8, score=20.6]} {RNA1509_6614} {RNA1310_3212} {RNA815_1655}

Mlig455_069449 {REF} {Length: 4564} {Pfam: Tetratricopeptide repeat [PF07719.19, score=38.1]; Tetratricopeptide repeat [PF14559.8, score=32.8]; Tetratricopeptide repeat [PF13428.8, score=30.9]; Tetratricopeptide repeat [PF13181.8, score=30.3]; Tetratricopeptide repeat [PF00515.30, score=25.2]; Tetratricopeptide repeat [PF13176.8, score=21.3]} {RNA1509_54886, RNA1509_57311, RNA1509_6614} {RNA1310_3212, RNA1509_54886, RNA1509_57311, RNA1509_6614} {RNA1509_54886, RNA1509_57311, RNA1509_6614, RNA815_1655}
49. MligTC455_38922 1324 27.57 Mlig455_055899

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.333

MX2 0.967 - - - - 0.967 - Mlig455_055899 {REF} {Length: 3320} {Pfam: Dynamin central region [PF01031.22, score=177.8]; Dynamin family [PF00350.25, score=125.7]; Dynamin GTPase effector domain [PF02212.20, score=46.3]; 50S ribosome-binding GTPase [PF01926.25, score=21.2]; AAA ATPase domain [PF13191.8, score=19.7]} {Human: ENSG00000183486, MX2, MX dynamin like GTPase 2, [Score=319, Expect=1e-97]} {Mouse: ENSMUSG00000023341, Mx2, MX dynamin-like GTPase 2, [Score=308, Expect=3e-94]} {Dmel: FBgn0003392, shi, shibire, [Score=182, Expect=9e-48]} {Celegans: WBGene00001130, dyn-1, Dynamin, [Score=176, Expect=6e-46]} {Smed: dd_Smed_v6_2583_0_1, dd_Smed_v6_2583_0_1, [Score=198, Expect=2e-53]} {RNA1509_37170, RNA1509_6400} {RNA1310_6542.1, RNA1509_37170, RNA1509_6400} {RNA1509_37170, RNA1509_6400, RNA815_1426.1}
50. MligTC455_52460 637 13.28 Mlig455_005945

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=4.277

0.967 - - - 0.967 - - Mlig455_005945 {REF} {Length: 1531} {Pfam: Kazal-type serine protease inhibitor domain [PF00050.23, score=105.7]; Kazal-type serine protease inhibitor domain [PF07648.17, score=90.0]} {Mouse: ENSMUSG00000041936, Agrn, agrin, [Score=52.4, Expect=5e-07]} {Dmel: FBgn0052354, CG32354, [Score=47.8, Expect=9e-06]} {Celegans: WBGene00009257, F29G6.1, [Score=49.7, Expect=2e-06]} {Smed: dd_Smed_v6_3649_0_1, dd_Smed_v6_3649_0_1, [Score=63.2, Expect=7e-11]} {RNA1509_43736} {RNA1310_32111} {RNA815_6190}
51. MligTC455_37414 739 15.39 Mlig455_056489

Neo: -

Age: Up-Down-Up

Region-enriched R4: 1.544/0.03051

0.963 - - - - 0.963 - Mlig455_056489 {REF} {Length: 4065} {Smed: dd_Smed_v6_8765_0_1, dd_Smed_v6_8765_0_1, [RH, Score=59.3, Expect=5e-10]} {RNA1509_20341} {RNA1310_15756.1} {RNA815_34876}
52. MligTC455_24345 161 3.36 Mlig455_001456

Neo: -

Age: -

0.962 - - 0.962 - - - Mlig455_001456 {REF} {Length: 3298} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=18.3]} {RNA1310_23364} {RNA815_42991}
53. MligTC455_33128 1820 37.91 Mlig455_065593

Neo: -

Age: -

0.961 - - 0.961 - - - Mlig455_065593 {REF} {Length: 2622} {TRANSSPLICED} {Pfam: HMG (high mobility group) box [PF00505.21, score=38.8]; HMG-box domain [PF09011.12, score=32.9]} {RNA1509_16997, RNA1509_20373, RNA1509_22468, RNA1509_29220, RNA1509_5450} {RNA1310_21659.1, RNA1509_16997, RNA1509_20373, RNA1509_22468, RNA1509_29220, RNA1509_5450} {RNA1509_16997, RNA1509_20373, RNA1509_22468, RNA1509_29220, RNA1509_5450, RNA815_736.1}
54. MligTC455_53628 724 15.09 Mlig455_060297

Neo: -

Age: Down-Up-Up

ADGRA3 0.96 - - 0.960 - - - Mlig455_060297 {REF} {Length: 2032} {Pfam: Leucine rich repeat [PF13855.8, score=61.4]} {Human: ENSG00000152990, ADGRA3, adhesion G protein-coupled receptor A3, [Score=49.3, Expect=1e-05]; ENSG00000187122, SLIT1, slit guidance ligand 1, [Score=49.3, Expect=1e-05]} {Mouse: ENSMUSG00000025020, Slit1, slit guidance ligand 1, [Score=50.8, Expect=2e-06]; ENSMUSG00000029090, Adgra3, adhesion G protein-coupled receptor A3, [Score=48.9, Expect=1e-05]; ENSMUSG00000044505, Lingo4, leucine rich repeat and Ig domain containing 4, [Score=48.5, Expect=1e-05]} {Dmel: FBgn0264089, sli, slit, [Score=53.5, Expect=2e-07]} {RNA1509_49012} {RNA1310_15910.1} {RNA815_6013}
55. MligTC455_04273 1905 39.69 Mlig455_014980, Mlig455_027959, Mlig455_027986, Mlig455_042890, Mlig455_056217

Neo: -

Age: logFC(26M/2M)=0.365

Region-enriched R4: 1.233/0.00679

0.959 - - 0.959 - - -

Mlig455_014980 {REF} {Length: 2410} {TRANSSPLICED} {Pfam: Plasmid protein of unknown function (Plasmid_RAQPRD) [PF09686.12, score=24.0]} {RNA1509_7158} {RNA1310_4079} {RNA815_282.1}

Mlig455_027959 {REF} {Length: 3263} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4806) [PF16064.7, score=33.3]} {RNA1509_33750} {RNA1310_4079} {RNA815_20382}

Mlig455_027986 {REF} {Length: 3151} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4806) [PF16064.7, score=33.3]} {RNA1509_33750} {RNA1310_4079} {RNA815_20382}

Mlig455_042890 {REF} {Length: 2273} {RNA1509_7158} {RNA1310_4079} {RNA815_282.1}

Mlig455_056217 {REF} {Length: 3151} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4806) [PF16064.7, score=33.3]} {RNA1509_33750} {RNA1310_4079} {RNA815_20382}
56. MligTC455_22760 1202 25.04 Mlig455_005448

Neo: -

Age: -

ELOVL4 0.959 - - - - 0.959 - Mlig455_005448 {REF} {Length: 1604} {TRANSSPLICED} {Pfam: GNS1/SUR4 family [PF01151.20, score=208.1]} {Human: ENSG00000118402, ELOVL4, ELOVL fatty acid elongase 4, [Score=284, Expect=2e-95]} {Mouse: ENSMUSG00000032262, Elovl4, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4, [Score=281, Expect=7e-95]} {Dmel: FBgn0052072, Elo68alpha, Elongase 68alpha, [Score=204, Expect=3e-65]} {Celegans: WBGene00001244, elo-6, Elongation of very long chain fatty acids protein 6, [Score=81.6, Expect=4e-18]} {Smed: dd_Smed_v6_7835_0_1, dd_Smed_v6_7835_0_1, [Score=286, Expect=2e-97]} {RNA1509_11261} {RNA1310_21427.2} {RNA815_6649.1}
57. MligTC455_32792 314 6.55 Mlig455_010871

Neo: -

Age: Down-Up-Up

Region-enriched R4: 2.924/0.00688

0.958 - - - - 0.958 - Mlig455_010871 {REF} {Length: 1226} {Pfam: Wnt and FGF inhibitory regulator [PF13908.8, score=23.1]} {Smed: dd_Smed_v6_5882_0_1, dd_Smed_v6_5882_0_1, [Score=73.9, Expect=3e-15]} {RNA1509_54110} {RNA1310_37559} {RNA815_18549}
58. MligTC455_34414 139 2.9 Mlig455_044232, Mlig455_044249

Neo: -

Age: -

C1GALT1 0.958 - - 0.958 - - -

Mlig455_044232 {REF} {Length: 1411} {Pfam: Fringe-like [PF02434.18, score=40.9]; Galactosyltransferase [PF01762.23, score=24.6]} {Human: ENSG00000106392, C1GALT1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=188, Expect=8e-57]} {Mouse: ENSMUSG00000042460, C1galt1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1, [Score=184, Expect=2e-55]} {Dmel: FBgn0031468, CG2975, [Score=174, Expect=2e-51]} {Celegans: WBGene00008019, C38H2.2, Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=194, Expect=4e-59]} {Smed: dd_Smed_v6_4310_0_1, dd_Smed_v6_4310_0_1, [Score=204, Expect=1e-63]} {RNA1310_37815} {RNA815_40424}

Mlig455_044249 {REF} {Length: 1563} {Pfam: Fringe-like [PF02434.18, score=39.1]; Galactosyltransferase [PF01762.23, score=22.8]} {Human: ENSG00000106392, C1GALT1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=191, Expect=2e-55]} {Mouse: ENSMUSG00000042460, C1galt1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1, [Score=185, Expect=1e-53]} {Dmel: FBgn0031468, CG2975, [Score=176, Expect=3e-50]} {Celegans: WBGene00008019, C38H2.2, Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=206, Expect=1e-61]} {Smed: dd_Smed_v6_4310_0_1, dd_Smed_v6_4310_0_1, [Score=207, Expect=2e-62]} {RNA1310_37815} {RNA815_40424}
59. MligTC455_46944 2203 45.9 Mlig455_006848, Mlig455_055094, Mlig455_055142

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.300

0.958 - - - - 0.958 -

Mlig455_006848 {REF} {Length: 3192} {Mouse: ENSMUSG00000021086, Ccdc175, coiled-coil domain containing 175, [RH, Score=57.4, Expect=5e-08]} {Smed: dd_Smed_v6_9798_0_1, dd_Smed_v6_9798_0_1, [RH, Score=291, Expect=2e-87]} {RNA1509_7270} {RNA1310_7123.1, RNA1509_7270} {RNA1509_7270, RNA815_2698}

Mlig455_055094 {REF} {Length: 2987} {Mouse: ENSMUSG00000021086, Ccdc175, coiled-coil domain containing 175, [RH, Score=57.4, Expect=5e-08]} {Smed: dd_Smed_v6_9798_0_1, dd_Smed_v6_9798_0_1, [RH, Score=291, Expect=2e-87]} {RNA1509_32123, RNA1509_58459, RNA1509_7270} {RNA1310_7123.1, RNA1509_32123, RNA1509_58459} {RNA1509_32123, RNA1509_58459, RNA815_2698}

Mlig455_055142 {REF} {Length: 2497} {Mouse: ENSMUSG00000021086, Ccdc175, coiled-coil domain containing 175, [RH, Score=57.8, Expect=4e-08]} {Smed: dd_Smed_v6_9798_0_1, dd_Smed_v6_9798_0_1, [RH, Score=287, Expect=9e-86]} {RNA1509_7270} {RNA1310_7123.1} {RNA815_2698}
60. MligTC455_47171 125 2.61 Mlig455_027708

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.385/0.02638

TCF7L2 0.958 - - - - 0.958 - Mlig455_027708 {REF} {Length: 4153} {TRANSSPLICED} {Pfam: HMG (high mobility group) box [PF00505.21, score=75.0]; HMG-box domain [PF09011.12, score=30.1]} {Human: ENSG00000148737, TCF7L2, transcription factor 7 like 2, [RH, Score=189, Expect=1e-50]; ENSG00000081059, TCF7, transcription factor 7, [RH, Score=185, Expect=4e-50]} {Mouse: ENSMUSG00000024985, Tcf7l2, transcription factor 7 like 2, T cell specific, HMG box, [Score=187, Expect=9e-50]} {Dmel: FBgn0085432, pan, pangolin, [RH, Score=188, Expect=2e-49]} {Celegans: WBGene00004077, pop-1, [RH, Score=118, Expect=4e-28]} {Smed: dd_Smed_v6_8152_0_1, dd_Smed_v6_8152_0_1, [RH, Score=193, Expect=4e-52]} {RNA1509_7090} {RNA1310_2735.1} {RNA815_5131}
61. MligTC455_49039 533 11.1 Mlig455_002546

Neo: Int S/G2/M

Age: -

Region-enriched R4: 1.825/0.02678

MMD 0.957 - - - - 0.957 - Mlig455_002546 {REF} {Length: 2081} {TRANSSPLICED} {Pfam: Haemolysin-III related [PF03006.22, score=88.4]} {Human: ENSG00000108960, MMD, monocyte to macrophage differentiation associated, [RH, Score=176, Expect=2e-54]} {Mouse: ENSMUSG00000003948, Mmd, monocyte to macrophage differentiation-associated, [RH, Score=175, Expect=3e-54]} {Dmel: FBgn0029935, CG4615, [RH, Score=186, Expect=1e-57]} {Celegans: WBGene00022158, Y71G12B.23, [RH, Score=167, Expect=5e-51]} {Smed: dd_Smed_v6_10316_0_1, dd_Smed_v6_10316_0_1, [RH, Score=207, Expect=4e-67]} {RNA1509_13493} {RNA1310_35755} {RNA815_14840.1}
62. MligTC455_26164 170 3.54 Mlig455_013776

Neo: -

Age: -

0.955 - - 0.955 - - - Mlig455_013776 {REF} {Length: 1666} {RNA1509_56028} {RNA1310_25129} {RNA815_10685.1}
63. MligTC455_19441 305 6.35 Mlig455_001985

Neo: -

Age: logFC(26M/2M)=-0.555

Region-enriched R2: 2.029/0.00606

0.954 - - 0.954 - - - Mlig455_001985 {REF} {Length: 2497} {RNA1509_40470} {RNA1310_22476.3, RNA1509_40470} {RNA1509_40470, RNA815_16128}
64. MligTC455_28953 140 2.91 Mlig455_015873

Neo: -

Age: -

0.954 - - - - 0.954 - Mlig455_015873 {REF} {Length: 3197} {TRANSSPLICED} {RNA1509_34212} {RNA1310_33751.1} {RNA815_19618}
65. MligTC455_30538 1019 21.24 Mlig455_016650, Mlig455_016715

Neo: -

Age: logFC(26M/2M)=-0.348

TTC6 0.953 - - - - 0.953 -

Mlig455_016650 {REF} {Length: 6488} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF00515.30, score=271.0]; Tetratricopeptide repeat [PF07719.19, score=229.3]; TPR repeat [PF13414.8, score=155.2]; Tetratricopeptide repeat [PF13432.8, score=146.1]; Tetratricopeptide repeat [PF13371.8, score=127.6]; Tetratricopeptide repeat [PF13181.8, score=125.1]; Tetratricopeptide repeat [PF13431.8, score=119.1]; Tetratricopeptide repeat [PF13424.8, score=96.5]; Tetratricopeptide repeat [PF13428.8, score=59.5]; Tetratricopeptide repeat [PF14559.8, score=59.5]; Anaphase-promoting complex, cyclosome, subunit 3 [PF12895.9, score=56.3]; Tetratricopeptide repeat [PF13176.8, score=46.2]; Tetratricopeptide repeat [PF13174.8, score=36.1]; Protein prenyltransferase alpha subunit repeat [PF01239.24, score=21.5]} {Human: ENSG00000139865, TTC6, tetratricopeptide repeat domain 6, [RH, Score=761, Expect=0.0]} {Mouse: ENSMUSG00000046782, Ttc6, tetratricopeptide repeat domain 6, [RH, Score=800, Expect=0.0]} {Dmel: FBgn0261403, sxc, super sex combs, [Score=108, Expect=4e-23]} {Celegans: WBGene00003858, ogt-1, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase, [Score=101, Expect=5e-21]} {Smed: dd_Smed_v6_11462_0_1, dd_Smed_v6_11462_0_1, [RH, Score=1009, Expect=0.0]} {RNA1509_3314} {RNA1310_528.1} {RNA815_2163}

Mlig455_016715 {REF} {Length: 6514} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF00515.30, score=266.3]; Tetratricopeptide repeat [PF07719.19, score=228.6]; TPR repeat [PF13414.8, score=152.7]; Tetratricopeptide repeat [PF13432.8, score=142.7]; Tetratricopeptide repeat [PF13371.8, score=128.6]; Tetratricopeptide repeat [PF13181.8, score=125.3]; Tetratricopeptide repeat [PF13431.8, score=116.3]; Tetratricopeptide repeat [PF13424.8, score=97.8]; Tetratricopeptide repeat [PF14559.8, score=59.5]; Anaphase-promoting complex, cyclosome, subunit 3 [PF12895.9, score=55.2]; Tetratricopeptide repeat [PF13428.8, score=53.7]; Tetratricopeptide repeat [PF13176.8, score=41.9]; Tetratricopeptide repeat [PF13174.8, score=36.6]; Protein prenyltransferase alpha subunit repeat [PF01239.24, score=21.0]} {Human: ENSG00000139865, TTC6, tetratricopeptide repeat domain 6, [RH, Score=757, Expect=0.0]} {Mouse: ENSMUSG00000046782, Ttc6, tetratricopeptide repeat domain 6, [RH, Score=796, Expect=0.0]} {Dmel: FBgn0261403, sxc, super sex combs, [Score=107, Expect=1e-22]} {Celegans: WBGene00003858, ogt-1, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase, [Score=100, Expect=8e-21]} {Smed: dd_Smed_v6_11462_0_1, dd_Smed_v6_11462_0_1, [RH, Score=1001, Expect=0.0]} {RNA1509_3314} {RNA1310_528.1, RNA1509_3314} {RNA1509_3314, RNA815_2163}
66. MligTC455_24896 589 12.28 Mlig455_042692

Neo: -

Age: -

PLCB4 0.952 - - 0.952 - - - Mlig455_042692 {REF} {Length: 7356} {TRANSSPLICED} {Pfam: Phosphatidylinositol-specific phospholipase C, Y domain [PF00387.21, score=119.1]; Protein of unknown function (DUF1154) [PF06631.13, score=49.3]; C2 domain [PF00168.32, score=24.4]} {Human: ENSG00000101333, PLCB4, phospholipase C beta 4, [Score=628, Expect=0.0]} {Mouse: ENSMUSG00000039943, Plcb4, phospholipase C, beta 4, [Score=630, Expect=0.0]} {Dmel: FBgn0262738, norpA, no receptor potential A, [Score=544, Expect=0.0]} {Celegans: WBGene00001177, egl-8, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8, [Score=558, Expect=0.0]} {Smed: dd_Smed_v6_3221_0_1, dd_Smed_v6_3221_0_1, [Score=651, Expect=0.0]} {RNA1509_34576, RNA1509_47225} {RNA1310_2178, RNA1509_34576} {RNA1509_34576, RNA815_911.1}
67. MligTC455_33127 1782 37.12 Mlig455_059339

Neo: -

Age: -

0.952 - - 0.952 - - - Mlig455_059339 {REF} {Length: 2630} {TRANSSPLICED} {Pfam: HMG (high mobility group) box [PF00505.21, score=38.7]; HMG-box domain [PF09011.12, score=32.9]} {RNA1509_33113, RNA1509_5450} {RNA1310_21659.1, RNA1509_33113} {RNA1509_33113, RNA815_736.1}
68. MligTC455_48063 63 1.31 Mlig455_046268

Neo: -

Age: -

Region-enriched R2: 5.256/0.00170

0.952 - - 0.952 - - - Mlig455_046268 {REF} {Length: 749} {RNA1310_88363} {RNA815_47885}
69. MligTC455_31557 51 1.07 Mlig455_021820

Neo: -

Age: -

0.951 - - - - 0.951 - Mlig455_021820 {REF} {Length: 2336} {NoTransDecoderORF} {RNA1509_33996} {RNA1310_11993} {RNA815_38913}
70. MligTC455_39337 938 19.53 Mlig455_039998

Neo: -

Age: logFC(26M/2M)=-0.274

NR1I2 0.951 - - 0.951 - - - Mlig455_039998 {REF} {Length: 6281} {TRANSSPLICED} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=65.3]} {Human: ENSG00000144852, NR1I2, nuclear receptor subfamily 1 group I member 2, [Score=80.5, Expect=2e-15]; ENSG00000143257, NR1I3, nuclear receptor subfamily 1 group I member 3, [Score=79.0, Expect=2e-15]; ENSG00000196482, ESRRG, estrogen related receptor gamma, [Score=77.0, Expect=2e-14]; ENSG00000173153, ESRRA, estrogen related receptor alpha, [Score=77.0, Expect=2e-14]} {Mouse: ENSMUSG00000005677, Nr1i3, nuclear receptor subfamily 1, group I, member 3, [Score=82.4, Expect=1e-16]} {Dmel: FBgn0015240, Hr96, Hormone receptor-like in 96, [Score=85.1, Expect=5e-17]} {Celegans: WBGene00003607, nhr-8, Nuclear hormone receptor family member nhr-8, [Score=89.4, Expect=1e-18]} {Smed: dd_Smed_v6_14067_0_2, dd_Smed_v6_14067_0_2, [RH, Score=94.0, Expect=5e-20]} {RNA1509_24367, RNA1509_36420, RNA1509_3835, RNA1509_43631, RNA1509_45925, RNA1509_55162, RNA1509_59667} {RNA1310_4758.2, RNA1509_24367, RNA1509_36420, RNA1509_3835, RNA1509_43631, RNA1509_45925, RNA1509_55162, RNA1509_59667} {RNA1509_24367, RNA1509_36420, RNA1509_3835, RNA1509_43631, RNA1509_45925, RNA1509_55162, RNA1509_59667, RNA815_2117}
71. MligTC455_10666 1029 21.43 Mlig455_033815, Mlig455_036255

Neo: -

Age: Down-Up-Down

0.95 - - 0.950 - - -

Mlig455_033815 {REF} {Length: 2235} {Pfam: CIDE-N domain [PF02017.17, score=45.6]} {RNA1509_6031} {RNA1310_3667} {RNA815_5199}

Mlig455_036255 {REF} {Length: 1884} {Pfam: CIDE-N domain [PF02017.17, score=46.3]} {RNA1509_6031} {RNA1310_3667} {RNA815_5199}
72. MligTC455_31921 3274 68.21 Mlig455_010083

Neo: -

Age: logFC(26M/2M)=-0.273

LAPTM4A 0.95 - - 0.950 - - - Mlig455_010083 {REF} {Length: 3539} {TRANSSPLICED} {Pfam: Golgi 4-transmembrane spanning transporter [PF03821.18, score=29.9]; Domain of unknown function (DUF4728) [PF15860.7, score=22.6]} {Human: ENSG00000068697, LAPTM4A, lysosomal protein transmembrane 4 alpha, [RH, Score=95.1, Expect=3e-22]} {Mouse: ENSMUSG00000020585, Laptm4a, lysosomal-associated protein transmembrane 4A, [RH, Score=83.6, Expect=7e-18]} {Dmel: FBgn0040777, CG14767, [RH, Score=107, Expect=7e-26]} {Smed: dd_Smed_v6_495_0_1, dd_Smed_v6_495_0_1, [RH, Score=92.8, Expect=2e-21]} {RNA1509_1981, RNA1509_19818, RNA1509_20796, RNA1509_21234, RNA1509_35266, RNA1509_36437, RNA1509_36744, RNA1509_56398, RNA1509_9912} {RNA1310_12676.1, RNA1509_19818, RNA1509_20796, RNA1509_21234, RNA1509_35266, RNA1509_36437, RNA1509_36744, RNA1509_56398, RNA1509_9912} {RNA1509_19818, RNA1509_20796, RNA1509_21234, RNA1509_35266, RNA1509_36437, RNA1509_36744, RNA1509_56398, RNA1509_9912, RNA815_5767.1}
73. MligTC455_31922 3315 69.06 Mlig455_010090

Neo: Int S/G2/M

Age: -

LAPTM4A 0.95 - - 0.950 - - - Mlig455_010090 {REF} {Length: 4183} {TRANSSPLICED} {Pfam: Golgi 4-transmembrane spanning transporter [PF03821.18, score=29.9]; Domain of unknown function (DUF4728) [PF15860.7, score=22.6]} {Human: ENSG00000068697, LAPTM4A, lysosomal protein transmembrane 4 alpha, [RH, Score=95.5, Expect=2e-22]} {Mouse: ENSMUSG00000020585, Laptm4a, lysosomal-associated protein transmembrane 4A, [RH, Score=84.0, Expect=5e-18]} {Dmel: FBgn0040777, CG14767, [RH, Score=106, Expect=2e-25]} {Smed: dd_Smed_v6_495_0_1, dd_Smed_v6_495_0_1, [RH, Score=93.2, Expect=2e-21]} {RNA1509_11987, RNA1509_12885, RNA1509_1632, RNA1509_18248, RNA1509_1981, RNA1509_24160, RNA1509_25385, RNA1509_26137, RNA1509_26880, RNA1509_30434, RNA1509_7963} {RNA1310_12676.1, RNA1509_11987, RNA1509_12885, RNA1509_1632, RNA1509_18248, RNA1509_1981, RNA1509_24160, RNA1509_25385, RNA1509_26137, RNA1509_26880, RNA1509_30434, RNA1509_7963} {RNA1509_11987, RNA1509_12885, RNA1509_1632, RNA1509_18248, RNA1509_1981, RNA1509_24160, RNA1509_25385, RNA1509_26137, RNA1509_26880, RNA1509_30434, RNA1509_7963, RNA815_5767.1}
74. MligTC455_51848 300 6.25 Mlig455_046814

Neo: -

Age: -

0.95 - - 0.950 - - - Mlig455_046814 {REF} {Length: 1471} {Pfam: WIF domain [PF02019.20, score=46.7]} {RNA1509_28045} {RNA1310_21900.2, RNA1509_28045} {RNA1509_28045, RNA815_9756}
75. MligTC455_53433 6029 125.61 Mlig455_004542, Mlig455_064733

Neo: -

Age: Down-Up-Up

RSPH4A 0.95 - - - - 0.950 -

Mlig455_004542 {REF} {Length: 1911} {TRANSSPLICED} {Pfam: Radial spokehead-like protein [PF04712.14, score=619.5]} {Human: ENSG00000111834, RSPH4A, radial spoke head component 4A, [RH, Score=442, Expect=4e-148]} {Mouse: ENSMUSG00000039552, Rsph4a, radial spoke head 4 homolog A (Chlamydomonas), [Score=448, Expect=2e-150]} {Dmel: FBgn0034957, CG3121, [Score=227, Expect=6e-66]} {Smed: dd_Smed_v6_5346_0_1, dd_Smed_v6_5346_0_1, [RH, Score=454, Expect=1e-155]} {RNA1509_6840} {RNA1310_12717.2} {RNA815_4800.1}

Mlig455_064733 {REF} {Length: 1911} {TRANSSPLICED} {Pfam: Radial spokehead-like protein [PF04712.14, score=619.5]} {Human: ENSG00000111834, RSPH4A, radial spoke head component 4A, [RH, Score=442, Expect=4e-148]} {Mouse: ENSMUSG00000039552, Rsph4a, radial spoke head 4 homolog A (Chlamydomonas), [Score=448, Expect=2e-150]} {Dmel: FBgn0034957, CG3121, [Score=227, Expect=6e-66]} {Smed: dd_Smed_v6_5346_0_1, dd_Smed_v6_5346_0_1, [RH, Score=454, Expect=1e-155]} {RNA1509_6840} {RNA1310_12717.2} {RNA815_4800.1}

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