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Results for MligTC455_48260

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_48260 78 1.63 Mlig455_020981

Neo: -

Age: -

CALM2 Mlig455_020981 {REF} {Length: 2098} {Pfam: EF hand [PF00036.34, score=97.7]; EF-hand domain pair [PF13499.8, score=83.8]; EF hand [PF13202.8, score=76.9]; EF-hand domain [PF13405.8, score=71.5]; EF-hand domain pair [PF13833.8, score=70.2]; EF-hand domain [PF14658.8, score=31.0]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=25.2]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=23.6]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=105, Expect=1e-27]; ENSG00000198668, CALM1, calmodulin 1, [Score=104, Expect=8e-28]; ENSG00000160014, CALM3, calmodulin 3, [Score=104, Expect=8e-28]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=105, Expect=8e-28]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=104, Expect=5e-28]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=104, Expect=5e-28]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=100, Expect=2e-26]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=103, Expect=8e-28]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=103, Expect=7e-28]} {Smed: dd_Smed_v6_11942_0_1, dd_Smed_v6_11942_0_1, [Score=104, Expect=3e-28]} {RNA1509_8417} {RNA1310_18928.1} {RNA815_18042.1}

Cumulative graph for MligTC455_48260

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 2.6 1.611 0.99990 1.00000
RegionR2 -1.723 1.611 0.99967 1.00000
RegionR3 -1.235 1.611 0.97002 1.00000
RegionR4 7.575 1.611 0.00913 0.05701
RegionR5 1.575 1.611 0.39562 0.75219
RegionR6 -0.719 1.611 0.95994 1.00000
RegionR7 -3.979 1.611 0.99970 1.00000
RegionR8 -4.094 1.611 0.99969 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.277 1.611 0.99994 1.00000
RegenerationR2 3.575 1.611 0.26193 0.70869
RegenerationR3 -0.609 1.611 0.32153 0.75020
RegenerationR4 -3.178 1.611 0.08409 0.45851
RegenerationR5 -1.309 1.611 0.31843 0.74212
RegenerationR6 -0.578 1.611 0.57554 0.85480
RegenerationBL 0.752 1.611 1.00000 1.00000
RegenerationTP -1.577 1.611 0.99990 1.00000


Genes with expression patterns similar to MligTC455_48260

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_48260 78 1.63 Mlig455_020981

Neo: -

Age: -

CALM2 2 - - - 1.000 - 1.000 Mlig455_020981 {REF} {Length: 2098} {Pfam: EF hand [PF00036.34, score=97.7]; EF-hand domain pair [PF13499.8, score=83.8]; EF hand [PF13202.8, score=76.9]; EF-hand domain [PF13405.8, score=71.5]; EF-hand domain pair [PF13833.8, score=70.2]; EF-hand domain [PF14658.8, score=31.0]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=25.2]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=23.6]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=105, Expect=1e-27]; ENSG00000198668, CALM1, calmodulin 1, [Score=104, Expect=8e-28]; ENSG00000160014, CALM3, calmodulin 3, [Score=104, Expect=8e-28]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=105, Expect=8e-28]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=104, Expect=5e-28]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=104, Expect=5e-28]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=100, Expect=2e-26]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=103, Expect=8e-28]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=103, Expect=7e-28]} {Smed: dd_Smed_v6_11942_0_1, dd_Smed_v6_11942_0_1, [Score=104, Expect=3e-28]} {RNA1509_8417} {RNA1310_18928.1} {RNA815_18042.1}
2. MligTC455_53682 393 8.18 Mlig455_064952, Mlig455_066834

Neo: -

Age: Down-Up-Up

Region-specific R2: 5.926

Region-enriched R2: 4.442/0.00896

1.956 - - - 0.959 - 0.997

Mlig455_064952 {REF} {Length: 1573} {Pfam: PAN domain [PF00024.28, score=20.0]} {RNA1310_33258} {RNA815_17150}

Mlig455_066834 {REF} {Length: 1573} {Pfam: PAN domain [PF00024.28, score=20.0]} {RNA1310_33258} {RNA815_17150}
3. MligTC455_17464 409 8.52 Mlig455_048989, Mlig455_049006, Mlig455_067762

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.512

Regeneration-downregulated BL: -7.800

Regeneration-depleted BL: -7.800

1.939 - - - 0.961 - 0.978

Mlig455_048989 {REF} {Length: 1272} {RNA1310_37715} {RNA815_39767}

Mlig455_049006 {REF} {Length: 1028} {RNA1310_37715} {RNA815_39767}

Mlig455_067762 {REF} {Length: 1353} {RNA1310_37715} {RNA815_39767}
4. MligTC455_19888 22 0.46 Mlig455_066525

Neo: -

Age: -

AC254952.1 1.939 - - - 0.993 - 0.946 Mlig455_066525 {REF} {Length: 1890} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=188.2]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=20.4]} {Human: ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=188, Expect=3e-55]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=188, Expect=3e-55]; ENSG00000166664, CHRFAM7A, CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion, [Score=188, Expect=5e-57]; ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=188, Expect=3e-55]; ENSG00000275917, CHRFAM7A, CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion, [Score=185, Expect=4e-56]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=195, Expect=4e-58]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=242, Expect=1e-75]} {Celegans: WBGene00000055, acr-16, Acetylcholine receptor subunit alpha-type acr-16, [Score=175, Expect=7e-51]} {Smed: dd_Smed_v6_12182_0_1, dd_Smed_v6_12182_0_1, [Score=228, Expect=9e-71]} {RNA1310_34222.1} {RNA815_33884}
5. MligTC455_36507 1422 29.63 Mlig455_038156, Mlig455_038261

Neo: -

Age: logFC(26M/2M)=-0.241

DNAI2 1.938 - - - 0.966 - 0.972

Mlig455_038156 {REF} {Length: 2699} {TRANSSPLICED} {Human: ENSG00000171595, DNAI2, dynein axonemal intermediate chain 2, [Score=534, Expect=0.0]} {Mouse: ENSMUSG00000034706, Dnaic2, dynein, axonemal, intermediate chain 2, [Score=513, Expect=1e-178]} {Dmel: FBgn0036195, Dnai2, dynein, axonemal, intermediate chain 2, [Score=386, Expect=4e-129]} {Smed: dd_Smed_v6_2644_0_1, dd_Smed_v6_2644_0_1, [Score=612, Expect=0.0]} {RNA1509_8245} {RNA1310_9583.1} {RNA815_3264}

Mlig455_038261 {REF} {Length: 2387} {TRANSSPLICED} {Human: ENSG00000171595, DNAI2, dynein axonemal intermediate chain 2, [RH, Score=756, Expect=0.0]} {Mouse: ENSMUSG00000034706, Dnaic2, dynein, axonemal, intermediate chain 2, [RH, Score=740, Expect=0.0]} {Dmel: FBgn0036195, Dnai2, dynein, axonemal, intermediate chain 2, [RH, Score=563, Expect=0.0]} {Smed: dd_Smed_v6_2644_0_1, dd_Smed_v6_2644_0_1, [RH, Score=867, Expect=0.0]} {RNA1509_8245} {RNA1310_9583.1} {RNA815_3264}
6. MligTC455_54204 344 7.17 Mlig455_006398

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.351

Region-specific R2: 5.395

Region-enriched R2: 4.187/0.01201

MYH6 1.936 - - - 0.958 - 0.978 Mlig455_006398 {REF} {Length: 7465} {Pfam: Myosin head (motor domain) [PF00063.23, score=927.6]; Myosin tail [PF01576.21, score=593.3]; Myosin N-terminal SH3-like domain [PF02736.21, score=60.7]; Crescentin protein [PF19220.2, score=26.4]; Macoilin family [PF09726.11, score=19.0]} {Human: ENSG00000197616, MYH6, myosin heavy chain 6, [RH, Score=2074, Expect=0.0]; ENSG00000092054, MYH7, myosin heavy chain 7, [RH, Score=2064, Expect=0.0]; ENSG00000125414, MYH2, myosin heavy chain 2, [RH, Score=2019, Expect=0.0]; ENSG00000109061, MYH1, myosin heavy chain 1, [RH, Score=2012, Expect=0.0]; ENSG00000133020, MYH8, myosin heavy chain 8, [RH, Score=2006, Expect=0.0]; ENSG00000264424, MYH4, myosin heavy chain 4, [RH, Score=1991, Expect=0.0]; ENSG00000109063, MYH3, myosin heavy chain 3, [RH, Score=1973, Expect=0.0]} {Mouse: ENSMUSG00000040752, Myh6, myosin, heavy polypeptide 6, cardiac muscle, alpha, [RH, Score=2073, Expect=0.0]; ENSMUSG00000053093, Myh7, myosin, heavy polypeptide 7, cardiac muscle, beta, [RH, Score=2063, Expect=0.0]; ENSMUSG00000057003, Myh4, myosin, heavy polypeptide 4, skeletal muscle, [RH, Score=2039, Expect=0.0]; ENSMUSG00000056328, Myh1, myosin, heavy polypeptide 1, skeletal muscle, adult, [RH, Score=2016, Expect=0.0]; ENSMUSG00000055775, Myh8, myosin, heavy polypeptide 8, skeletal muscle, perinatal, [RH, Score=2014, Expect=0.0]; ENSMUSG00000033196, Myh2, myosin, heavy polypeptide 2, skeletal muscle, adult, [RH, Score=2008, Expect=0.0]; ENSMUSG00000020908, Myh3, myosin, heavy polypeptide 3, skeletal muscle, embryonic, [RH, Score=1981, Expect=0.0]; ENSMUSG00000060180, Myh13, myosin, heavy polypeptide 13, skeletal muscle, [RH, Score=1978, Expect=0.0]} {Dmel: FBgn0264695, Mhc, Myosin heavy chain, [RH, Score=2100, Expect=0.0]} {Celegans: WBGene00019064, myo-5, MYOsin heavy chain structural genes, [RH, Score=1993, Expect=0.0]} {Smed: dd_Smed_v6_579_0_1, dd_Smed_v6_579_0_1, [RH, Score=2702, Expect=0.0]} {RNA1509_16048, RNA1509_42411} {RNA1310_1388, RNA1509_42411} {RNA1509_42411, RNA815_129.1}
7. MligTC455_19908 490 10.21 Mlig455_047266, Mlig455_047318, Mlig455_069346

Neo: -

Age: logFC(26M/2M)=0.566

1.933 - - - 0.960 - 0.973

Mlig455_047266 {REF} {Length: 1728} {Pfam: Glycine rich protein [PF12810.9, score=49.4]} {RNA1509_28009} {RNA1310_17226} {RNA815_32720}

Mlig455_047318 {REF} {Length: 2268} {Pfam: Glycine rich protein [PF12810.9, score=36.7]} {RNA1509_28009} {RNA1310_17226, RNA1509_28009} {RNA1509_28009, RNA815_32720}

Mlig455_069346 {REF} {Length: 1953} {Pfam: Glycine rich protein [PF12810.9, score=31.6]} {RNA1509_28009} {RNA1310_17226} {RNA815_32720}
8. MligTC455_22098 31 0.66 Mlig455_004396, Mlig455_037219

Neo: -

Age: -

1.932 - - - 0.947 - 0.985

Mlig455_004396 {REF} {Length: 1521} {RNA1310_40784}

Mlig455_037219 {REF} {Length: 1583} {RNA1310_63625}
9. MligTC455_16096 69 1.44 Mlig455_059809

Neo: -

Age: -

ANGPTL1 1.925 - - - 0.942 - 0.983 Mlig455_059809 {REF} {Length: 1391} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=117.9]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=109, Expect=1e-26]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=106, Expect=2e-25]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=110, Expect=3e-27]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=105, Expect=2e-25]} {Dmel: FBgn0003326, sca, scabrous, [Score=91.3, Expect=3e-20]} {Celegans: WBGene00017013, ensh-1, [Score=61.2, Expect=1e-10]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=77.8, Expect=5e-16]} {RNA1509_28467} {RNA1310_47262} {RNA815_18070.1}
10. MligTC455_21754 21 0.44 Mlig455_021167

Neo: -

Age: Down-Up-Down

1.922 - - - 0.937 - 0.985 Mlig455_021167 {REF} {Length: 1412} {Pfam: F5/8 type C domain [PF00754.27, score=37.1]} {RNA1310_25631} {RNA815_14716}
11. MligTC455_15492 69 1.44 Mlig455_022488

Neo: -

Age: Down-Up-Up

1.917 - - - 0.936 - 0.981 Mlig455_022488 {REF} {Length: 1351} {RNA1310_26051} {RNA815_10966}
12. MligTC455_40989 801 16.68 Mlig455_016294

Neo: -

Age: logFC(26M/2M)=0.270

PKD2 1.917 - - - 0.941 - 0.976 Mlig455_016294 {REF} {Length: 3179} {Pfam: Polycystin cation channel [PF08016.14, score=486.5]; Ion transport protein [PF00520.33, score=90.3]; EF hand [PF00036.34, score=23.7]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=718, Expect=0.0]; ENSG00000107593, PKD2L1, polycystin 2 like 1, transient receptor potential cation channel, [RH, Score=712, Expect=0.0]} {Mouse: ENSMUSG00000037578, Pkd2l1, polycystic kidney disease 2-like 1, [RH, Score=704, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [RH, Score=310, Expect=2e-91]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [RH, Score=370, Expect=7e-116]} {Smed: dd_Smed_v6_13327_0_1, dd_Smed_v6_13327_0_1, [RH, Score=743, Expect=0.0]} {RNA1509_14023, RNA1509_24240} {RNA1310_4836.1, RNA1509_14023, RNA1509_24240} {RNA1509_14023, RNA1509_24240, RNA815_4677}
13. MligTC455_41694 404 8.41 Mlig455_026434, Mlig455_026464

Neo: -

Age: -

SSUH2 1.916 - - - 0.935 - 0.981

Mlig455_026434 {REF} {Length: 1709} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=210, Expect=4e-64]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=177, Expect=5e-52]} {RNA1509_35286} {RNA1310_19837, RNA1509_35286} {RNA1509_35286, RNA815_11262}

Mlig455_026464 {REF} {Length: 1584} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=210, Expect=7e-64]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=178, Expect=4e-52]} {RNA1509_35286} {RNA1310_19837} {RNA815_11262}
14. MligTC455_21755 70 1.47 Mlig455_021213

Neo: -

Age: -

1.914 - - - 0.932 - 0.982 Mlig455_021213 {REF} {Length: 4215} {Pfam: F5/8 type C domain [PF00754.27, score=55.5]} {RNA1509_2515} {RNA1310_33166} {RNA815_14716}
15. MligTC455_13102 65 1.35 Mlig455_056246

Neo: -

Age: Up-Down-Down

Region-enriched R2: 6.206/0.00027

NWD2 1.912 - - - 0.959 - 0.953 Mlig455_056246 {REF} {Length: 8104} {Pfam: NACHT domain [PF05729.14, score=51.2]; AAA ATPase domain [PF13191.8, score=36.8]; Domain of unknown function (DUF4062) [PF13271.8, score=36.5]; ATPase domain predominantly from Archaea [PF01637.20, score=23.7]; AAA domain [PF13401.8, score=20.6]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=451, Expect=2e-130]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [RH, Score=436, Expect=2e-125]} {Dmel: FBgn0038397, CG10185, [RH, Score=980, Expect=0.0]} {Celegans: WBGene00020254, T05C3.2, [RH, Score=925, Expect=0.0]} {Smed: dd_Smed_v6_11085_0_1, dd_Smed_v6_11085_0_1, [Score=344, Expect=9e-96]} {RNA1509_20730} {RNA1310_1147} {RNA815_11922}
16. MligTC455_14293 27 0.55 Mlig455_005699

Neo: -

Age: -

1.912 - - - 0.927 - 0.985 Mlig455_005699 {REF} {Length: 220} {NoTransDecoderORF} {RNA1509_35414} {RNA1310_4580}
17. MligTC455_54203 182 3.79 Mlig455_061249

Neo: -

Age: -

MYH7 1.911 - - - 0.953 - 0.958 Mlig455_061249 {REF} {Length: 1536} {Pfam: Myosin tail [PF01576.21, score=90.6]} {Human: ENSG00000092054, MYH7, myosin heavy chain 7, [Score=200, Expect=8e-57]; ENSG00000197616, MYH6, myosin heavy chain 6, [Score=198, Expect=4e-56]; ENSG00000264424, MYH4, myosin heavy chain 4, [Score=191, Expect=2e-53]; ENSG00000125414, MYH2, myosin heavy chain 2, [Score=190, Expect=4e-53]} {Mouse: ENSMUSG00000053093, Myh7, myosin, heavy polypeptide 7, cardiac muscle, beta, [Score=201, Expect=4e-57]; ENSMUSG00000040752, Myh6, myosin, heavy polypeptide 6, cardiac muscle, alpha, [Score=194, Expect=8e-55]; ENSMUSG00000057003, Myh4, myosin, heavy polypeptide 4, skeletal muscle, [Score=192, Expect=3e-54]; ENSMUSG00000056328, Myh1, myosin, heavy polypeptide 1, skeletal muscle, adult, [Score=191, Expect=1e-53]} {Dmel: FBgn0264695, Mhc, Myosin heavy chain, [Score=282, Expect=2e-85]} {Celegans: WBGene00003515, myo-3, Myosin-3, [Score=241, Expect=2e-71]} {Smed: dd_Smed_v6_432_0_1, dd_Smed_v6_432_0_1, [Score=285, Expect=9e-87]} {RNA1509_55838} {RNA1310_1388} {RNA815_21073}
18. MligTC455_36730 165 3.44 Mlig455_056961

Neo: -

Age: Up-Down-Down

1.91 - - - 0.918 - 0.992 Mlig455_056961 {REF} {Length: 4865} {Pfam: Lipoma HMGIC fusion partner-like protein [PF10242.11, score=57.3]} {RNA1310_49374} {RNA815_39552}
19. MligTC455_43324 71 1.47 Mlig455_041984

Neo: -

Age: -

Region-enriched R2: 6.623/0.00573

1.91 - - - 0.956 - 0.954 Mlig455_041984 {REF} {Length: 388} {NoTransDecoderORF} {RNA1509_49821} {RNA1310_52560.2} {RNA815_59873}
20. MligTC455_18269 27 0.56 Mlig455_008658

Neo: -

Age: -

1.909 - - - 0.924 - 0.985 Mlig455_008658 {REF} {Length: 1290} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=19.1]} {RNA1509_25258} {RNA1310_4580, RNA1509_25258} {RNA1509_25258, RNA815_9496.1}
21. MligTC455_32644 41 0.86 Mlig455_043770, Mlig455_043786

Neo: -

Age: -

Region-enriched R2: 6.705/0.00336

1.909 - - - 0.924 - 0.985

Mlig455_043770 {REF} {Length: 1011} {Pfam: PAN domain [PF00024.28, score=19.3]} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=60.8, Expect=3e-11]} {RNA1509_35604} {RNA1310_57814} {RNA815_29718}

Mlig455_043786 {REF} {Length: 1348} {Pfam: PAN domain [PF00024.28, score=19.3]} {RNA1509_35604} {RNA1310_34182} {RNA815_29718}
22. MligTC455_39874 143 2.98 Mlig455_049425

Neo: -

Age: -

PKDCC 1.907 - - - 0.919 - 0.988 Mlig455_049425 {REF} {Length: 3789} {Pfam: Protein-kinase domain of FAM69 [PF12260.10, score=30.6]; Protein kinase domain [PF00069.27, score=21.0]} {Human: ENSG00000162878, PKDCC, protein kinase domain containing, cytoplasmic, [RH, Score=192, Expect=4e-55]} {Mouse: ENSMUSG00000024247, Pkdcc, protein kinase domain containing, cytoplasmic, [RH, Score=180, Expect=9e-51]} {RNA1310_12305} {RNA815_19030.1}
23. MligTC455_40353 39 0.82 Mlig455_024525

Neo: -

Age: -

1.907 - - - 0.937 - 0.970 Mlig455_024525 {REF} {Length: 1158} {RNA1310_29008}
24. MligTC455_40610 165 3.43 Mlig455_064484

Neo: -

Age: -

Region-enriched R2: 5.617/0.00105

1.907 - - - 0.922 - 0.985 Mlig455_064484 {REF} {Length: 2931} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=24.9]} {Smed: dd_Smed_v6_41498_0_1, dd_Smed_v6_41498_0_1, [Score=154, Expect=2e-40]} {RNA1509_26568} {RNA1310_9342.1, RNA1509_26568} {RNA1509_26568, RNA815_7018}
25. MligTC455_35701 66 1.37 Mlig455_010067, Mlig455_063254, Mlig455_063279

Neo: -

Age: Up-Down-Down

Region-enriched R2: 4.716/0.02468

1.905 - - - 0.930 - 0.975

Mlig455_010067 {REF} {Length: 2624} {Pfam: Polycystin cation channel [PF08016.14, score=46.7]} {RNA1310_62521}

Mlig455_063254 {REF} {Length: 2738} {Pfam: Polycystin cation channel [PF08016.14, score=43.3]; Lipopolysaccharide assembly protein A domain [PF06305.13, score=18.4]} {RNA1509_7418} {RNA1310_62521} {RNA815_3659}

Mlig455_063279 {REF} {Length: 2677} {Pfam: Polycystin cation channel [PF08016.14, score=46.0]} {RNA1310_62521}
26. MligTC455_49926 50 1.04 Mlig455_062317

Neo: -

Age: -

VSX1 1.905 - - - 0.926 - 0.979 Mlig455_062317 {REF} {Length: 1610} {Pfam: Homeodomain [PF00046.31, score=79.8]} {Human: ENSG00000100987, VSX1, visual system homeobox 1, [RH, Score=202, Expect=4e-61]; ENSG00000119614, VSX2, visual system homeobox 2, [RH, Score=201, Expect=1e-60]} {Mouse: ENSMUSG00000021239, Vsx2, visual system homeobox 2, [RH, Score=201, Expect=8e-61]; ENSMUSG00000033080, Vsx1, visual system homeobox 1, [RH, Score=198, Expect=2e-59]} {Dmel: FBgn0263512, Vsx2, Visual system homeobox 2, [RH, Score=208, Expect=6e-61]} {Celegans: WBGene00000435, ceh-10, Homeobox protein ceh-10, [RH, Score=210, Expect=1e-64]} {Smed: dd_Smed_v6_19286_0_1, dd_Smed_v6_19286_0_1, [RH, Score=212, Expect=1e-65]} {RNA1310_39008} {RNA815_19602}
27. MligTC455_17568 33 0.68 Mlig455_059349, Mlig455_065584

Neo: -

Age: -

1.904 - - - 0.919 - 0.985

Mlig455_059349 {REF} {Length: 1132} {RNA1509_24218} {RNA1310_25312.1} {RNA815_12390}

Mlig455_065584 {REF} {Length: 1132} {RNA1509_24218} {RNA1310_25312.1} {RNA815_12390}
28. MligTC455_16415 197 4.1 Mlig455_000401

Neo: -

Age: -

Region-enriched R2: 4.276/0.00982

ROR1 1.903 - - - 0.921 - 0.982 Mlig455_000401 {REF} {Length: 3780} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=233.3]; Protein kinase domain [PF00069.27, score=85.9]; Immunoglobulin I-set domain [PF07679.18, score=49.4]; Immunoglobulin domain [PF13927.8, score=46.6]; Immunoglobulin domain [PF00047.27, score=31.9]; Immunoglobulin domain [PF13895.8, score=30.0]; Fz domain [PF01392.24, score=27.6]; Kringle domain [PF00051.20, score=22.3]; Immunoglobulin V-set domain [PF07686.19, score=19.5]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [RH, Score=390, Expect=1e-119]; ENSG00000169071, ROR2, receptor tyrosine kinase like orphan receptor 2, [RH, Score=379, Expect=1e-115]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [RH, Score=386, Expect=1e-118]; ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [RH, Score=377, Expect=4e-115]} {Dmel: FBgn0010407, Ror, [Score=286, Expect=3e-84]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=285, Expect=4e-82]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [RH, Score=439, Expect=2e-139]} {RNA1509_35395} {RNA1310_13558, RNA1509_35395} {RNA1509_35395, RNA815_27446}
29. MligTC455_29929 164 3.41 Mlig455_030237, Mlig455_068015

Neo: -

Age: -

Region-enriched R2: 4.901/0.00350

SIX6 1.902 - - - 0.917 - 0.985

Mlig455_030237 {REF} {Length: 2545} {Pfam: Transcriptional regulator, SIX1, N-terminal SD domain [PF16878.7, score=152.1]; Homeodomain [PF00046.31, score=46.4]; Homeobox KN domain [PF05920.13, score=40.1]} {Human: ENSG00000184302, SIX6, SIX homeobox 6, [RH, Score=327, Expect=1e-109]; ENSG00000138083, SIX3, SIX homeobox 3, [RH, Score=325, Expect=8e-108]} {Mouse: ENSMUSG00000038805, Six3, sine oculis-related homeobox 3, [RH, Score=325, Expect=6e-108]; ENSMUSG00000021099, Six6, sine oculis-related homeobox 6, [RH, Score=323, Expect=2e-108]} {Dmel: FBgn0025360, Optix, [RH, Score=291, Expect=9e-93]} {Celegans: WBGene00000453, ceh-32, Homeobox protein ceh-32, [RH, Score=237, Expect=2e-72]} {Smed: dd_Smed_v6_11975_0_1, dd_Smed_v6_11975_0_1, [RH, Score=360, Expect=2e-119]} {RNA1509_39396} {RNA1310_25182.2} {RNA815_23127}

Mlig455_068015 {REF} {Length: 2713} {Pfam: Transcriptional regulator, SIX1, N-terminal SD domain [PF16878.7, score=152.2]; Homeodomain [PF00046.31, score=46.4]; Homeobox KN domain [PF05920.13, score=40.1]} {Human: ENSG00000184302, SIX6, SIX homeobox 6, [RH, Score=327, Expect=1e-109]; ENSG00000138083, SIX3, SIX homeobox 3, [RH, Score=325, Expect=7e-108]} {Mouse: ENSMUSG00000038805, Six3, sine oculis-related homeobox 3, [RH, Score=325, Expect=5e-108]; ENSMUSG00000021099, Six6, sine oculis-related homeobox 6, [RH, Score=323, Expect=2e-108]} {Dmel: FBgn0025360, Optix, [RH, Score=291, Expect=1e-92]} {Celegans: WBGene00000453, ceh-32, Homeobox protein ceh-32, [RH, Score=237, Expect=1e-72]} {Smed: dd_Smed_v6_11975_0_1, dd_Smed_v6_11975_0_1, [RH, Score=360, Expect=1e-119]} {RNA1509_39396} {RNA1310_25182.2} {RNA815_23127}
30. MligTC455_40228 146 3.03 Mlig455_010654, Mlig455_010753

Neo: -

Age: logFC(26M/2M)=0.372

Region-enriched R2: 5.064/0.02014

KY 1.9 - - - 0.916 - 0.984

Mlig455_010654 {REF} {Length: 3057} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=103, Expect=6e-22]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=113, Expect=2e-25]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=373, Expect=6e-115]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [RH, Score=347, Expect=3e-106]} {Smed: dd_Smed_v6_1846_0_1, dd_Smed_v6_1846_0_1, [Score=207, Expect=1e-55]} {RNA1509_35609} {RNA1310_6947.1} {RNA815_20684}

Mlig455_010753 {REF} {Length: 3328} {Pfam: LIM domain [PF00412.24, score=33.6]} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=104, Expect=3e-22]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=114, Expect=2e-25]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=376, Expect=1e-115]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [RH, Score=353, Expect=4e-108]} {Smed: dd_Smed_v6_1846_0_1, dd_Smed_v6_1846_0_1, [Score=207, Expect=2e-55]} {RNA1509_35609} {RNA1310_6947.1, RNA1509_35609} {RNA1509_35609, RNA815_20684}
31. MligTC455_46395 870 18.13 Mlig455_069471

Neo: -

Age: logFC(26M/2M)=0.458

PKD2 1.9 - - - 0.942 - 0.958 Mlig455_069471 {REF} {Length: 3122} {TRANSSPLICED} {Pfam: Polycystin cation channel [PF08016.14, score=487.8]; Ion transport protein [PF00520.33, score=93.3]; EF hand [PF00036.34, score=32.7]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=21.3]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=753, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=750, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=323, Expect=1e-96]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=387, Expect=8e-123]} {Smed: dd_Smed_v6_13327_0_1, dd_Smed_v6_13327_0_1, [RH, Score=769, Expect=0.0]} {RNA1509_13522} {RNA1310_21296.2} {RNA815_3158.1}
32. MligTC455_51051 233 4.85 Mlig455_046293

Neo: -

Age: -

1.9 - - - 0.929 - 0.971 Mlig455_046293 {REF} {Length: 1585} {RNA1310_32253}
33. MligTC455_13171 25 0.53 Mlig455_005963, Mlig455_005967

Neo: -

Age: -

1.899 - - - 0.915 - 0.984

Mlig455_005963 {REF} {Length: 2617} {RNA1509_20946} {RNA1310_146331} {RNA815_35450}

Mlig455_005967 {REF} {Length: 1405} {Pfam: Lectin C-type domain [PF00059.23, score=20.7]} {RNA1509_20946} {RNA1310_146331} {RNA815_35450}
34. MligTC455_53842 1222 25.46 Mlig455_023890

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.345

Region-enriched R2: 1.546/0.01667

1.899 - - - 0.940 - 0.959 Mlig455_023890 {REF} {Length: 1336} {RNA1509_15580} {RNA1310_22487.1} {RNA815_10676.1}
35. MligTC455_37720 156 3.25 Mlig455_027725, Mlig455_027921, Mlig455_027931

Neo: -

Age: Up-Down-Down

Region-enriched R2: 4.630/0.03113

TRPV6 1.898 - - - 0.922 - 0.976

Mlig455_027725 {REF} {Length: 5690} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=53.7]; Ion transport protein [PF00520.33, score=39.6]; Ankyrin repeat [PF13606.8, score=33.0]; Ankyrin repeats (many copies) [PF13857.8, score=30.8]; Ankyrin repeat [PF00023.32, score=29.7]; Polycystin cation channel [PF08016.14, score=27.5]; Ankyrin repeats (many copies) [PF13637.8, score=21.3]} {Human: ENSG00000165125, TRPV6, transient receptor potential cation channel subfamily V member 6, [RH, Score=207, Expect=4e-55]; ENSG00000276971, TRPV6, transient receptor potential cation channel subfamily V member 6, [RH, Score=206, Expect=4e-55]} {Mouse: ENSMUSG00000029868, Trpv6, transient receptor potential cation channel, subfamily V, member 6, [Score=206, Expect=1e-54]} {Dmel: FBgn0086693, iav, inactive, [RH, Score=568, Expect=0.0]} {Celegans: WBGene00003889, osm-9, Olfactory channel, [RH, Score=489, Expect=8e-156]} {Smed: dd_Smed_v6_28914_0_1, dd_Smed_v6_28914_0_1, [Score=492, Expect=6e-158]} {RNA1509_36869} {RNA1310_5278, RNA1509_36869} {RNA1509_36869, RNA815_5723}

Mlig455_027921 {REF} {Length: 8298} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=53.7]; Ion transport protein [PF00520.33, score=39.2]; Ankyrin repeat [PF13606.8, score=33.0]; Ankyrin repeats (many copies) [PF13857.8, score=30.8]; Ankyrin repeat [PF00023.32, score=29.8]; Polycystin cation channel [PF08016.14, score=27.1]; Ankyrin repeats (many copies) [PF13637.8, score=21.3]} {Human: ENSG00000165125, TRPV6, transient receptor potential cation channel subfamily V member 6, [RH, Score=207, Expect=4e-55]; ENSG00000276971, TRPV6, transient receptor potential cation channel subfamily V member 6, [RH, Score=206, Expect=5e-55]} {Mouse: ENSMUSG00000029868, Trpv6, transient receptor potential cation channel, subfamily V, member 6, [Score=206, Expect=9e-55]} {Dmel: FBgn0086693, iav, inactive, [RH, Score=566, Expect=0.0]} {Celegans: WBGene00003889, osm-9, Olfactory channel, [RH, Score=488, Expect=1e-155]} {Smed: dd_Smed_v6_28914_0_1, dd_Smed_v6_28914_0_1, [Score=491, Expect=1e-157]} {RNA1509_36869} {RNA1310_5278} {RNA815_5723}

Mlig455_027931 {REF} {Length: 6147} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=53.7]; Ion transport protein [PF00520.33, score=40.0]; Ankyrin repeat [PF13606.8, score=34.3]; Ankyrin repeats (many copies) [PF13857.8, score=31.5]; Ankyrin repeat [PF00023.32, score=30.2]; Polycystin cation channel [PF08016.14, score=27.8]; Ankyrin repeats (many copies) [PF13637.8, score=21.7]} {Human: ENSG00000276971, TRPV6, transient receptor potential cation channel subfamily V member 6, [RH, Score=208, Expect=7e-56]; ENSG00000165125, TRPV6, transient receptor potential cation channel subfamily V member 6, [RH, Score=207, Expect=1e-55]} {Mouse: ENSMUSG00000029868, Trpv6, transient receptor potential cation channel, subfamily V, member 6, [Score=206, Expect=3e-55]} {Dmel: FBgn0086693, iav, inactive, [RH, Score=567, Expect=0.0]} {Celegans: WBGene00003889, osm-9, Olfactory channel, [RH, Score=488, Expect=5e-157]} {Smed: dd_Smed_v6_28914_0_1, dd_Smed_v6_28914_0_1, [Score=490, Expect=4e-159]} {RNA1509_36869} {RNA1310_5278} {RNA815_5723}
36. MligTC455_54338 49 1.02 Mlig455_056485

Neo: -

Age: Up-Down-Down

PKDREJ 1.897 - - - 0.931 - 0.966 Mlig455_056485 {REF} {Length: 11174} {Pfam: Polycystin cation channel [PF08016.14, score=290.0]; REJ domain [PF02010.17, score=90.7]; PLAT/LH2 domain [PF01477.25, score=67.3]; PKD domain [PF00801.22, score=47.7]; Ion transport protein [PF00520.33, score=40.1]; PKD domain [PF18911.2, score=29.8]; GPCR proteolysis site, GPS, motif [PF01825.23, score=27.4]; WSC domain [PF01822.21, score=27.0]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=280, Expect=1e-74]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=307, Expect=8e-83]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=151, Expect=3e-36]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [RH, Score=302, Expect=1e-81]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [RH, Score=1844, Expect=0.0]} {RNA1509_16432} {RNA1310_1236} {RNA815_2411}
37. MligTC455_24108 17 0.35 Mlig455_019116

Neo: -

Age: -

KCNK16 1.896 - - - 0.911 - 0.985 Mlig455_019116 {REF} {Length: 1389} {Pfam: Ion channel [PF07885.18, score=118.0]; Ion transport protein [PF00520.33, score=29.1]} {Human: ENSG00000095981, KCNK16, potassium two pore domain channel subfamily K member 16, [Score=155, Expect=5e-44]} {Mouse: ENSMUSG00000023243, Kcnk5, potassium channel, subfamily K, member 5, [RH, Score=141, Expect=3e-37]} {Dmel: FBgn0037690, Task7, TWIK-related acid-sensitive K[+] channel 7, [Score=110, Expect=3e-27]} {Celegans: WBGene00006696, twk-46, TWiK family of potassium channels, [Score=115, Expect=3e-29]} {Smed: dd_Smed_v6_9028_0_1, dd_Smed_v6_9028_0_1, [Score=121, Expect=4e-31]} {RNA1310_125949}
38. MligTC455_29828 3825 79.69 Mlig455_005927, Mlig455_028571

Neo: -

Age: -

Region-enriched R2: 2.078/0.00752

AOX1 1.896 - - - 0.945 - 0.951

Mlig455_005927 {REF} {Length: 5419} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=393.8]; [2Fe-2S] binding domain [PF01799.22, score=95.8]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=88.5]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=82.6]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=60.0]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=21.6]} {Human: ENSG00000138356, AOX1, aldehyde oxidase 1, [Score=461, Expect=1e-139]; ENSG00000158125, XDH, xanthine dehydrogenase, [Score=454, Expect=4e-137]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=468, Expect=2e-142]; ENSMUSG00000063558, Aox1, aldehyde oxidase 1, [Score=449, Expect=1e-135]} {Dmel: FBgn0267408, AOX1, Aldehyde oxidase 1, [Score=665, Expect=0.0]} {Celegans: WBGene00010083, xhd-1, [Score=506, Expect=1e-156]} {RNA1509_1345} {RNA1310_1703.1, RNA1509_1345} {RNA1509_1345, RNA815_528.1}

Mlig455_028571 {REF} {Length: 5081} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=393.8]; [2Fe-2S] binding domain [PF01799.22, score=95.8]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=88.5]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=82.6]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=60.0]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=21.6]} {Human: ENSG00000138356, AOX1, aldehyde oxidase 1, [Score=459, Expect=5e-139]; ENSG00000158125, XDH, xanthine dehydrogenase, [Score=453, Expect=6e-137]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=467, Expect=3e-142]; ENSMUSG00000063558, Aox1, aldehyde oxidase 1, [Score=450, Expect=9e-136]} {Dmel: FBgn0267408, AOX1, Aldehyde oxidase 1, [Score=665, Expect=0.0]} {Celegans: WBGene00010083, xhd-1, [Score=506, Expect=1e-156]} {RNA1509_1345, RNA1509_30386} {RNA1310_1703.1, RNA1509_30386} {RNA1509_30386, RNA815_528.1}
39. MligTC455_39481 461 9.6 Mlig455_056703, Mlig455_060318

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.222

ANGPTL1 1.896 - - - 0.919 - 0.977

Mlig455_056703 {REF} {Length: 1114} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=79.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=89.4, Expect=1e-19]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=85.1, Expect=3e-18]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=91.3, Expect=2e-20]} {Dmel: FBgn0033312, CG8642, [Score=82.4, Expect=1e-17]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=76.3, Expect=1e-15]} {RNA1310_31288} {RNA815_20497.1}

Mlig455_060318 {REF} {Length: 1175} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=112.7]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=106, Expect=2e-25]; ENSG00000171819, ANGPTL7, angiopoietin like 7, [Score=105, Expect=6e-26]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=109, Expect=1e-26]} {Dmel: FBgn0034160, CG5550, [Score=96.3, Expect=2e-23]} {Celegans: WBGene00016769, C49C8.5, [Score=47.0, Expect=9e-06]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=88.2, Expect=2e-19]} {RNA1310_31288} {RNA815_20497.1}
40. MligTC455_33001 2993 62.36 Mlig455_021328

Neo: -

Age: Down-Down-Up

Regeneration-downregulated BL: -1.699

Regeneration-depleted BL: -1.699

PLSCR1 1.895 - - - 0.936 - 0.959 Mlig455_021328 {REF} {Length: 1467} {Pfam: Scramblase [PF03803.17, score=250.1]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=218, Expect=1e-69]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=216, Expect=9e-69]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=212, Expect=2e-67]} {Dmel: FBgn0035390, scramb2, scramblase 2, [RH, Score=223, Expect=2e-72]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=197, Expect=1e-62]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [Score=279, Expect=4e-94]} {RNA1509_23323, RNA1509_2687} {RNA1310_25112, RNA1509_23323, RNA1509_2687} {RNA1509_23323, RNA1509_2687, RNA815_11532}
41. MligTC455_19114 79 1.64 Mlig455_045107

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.813

1.894 - - - 0.911 - 0.983 Mlig455_045107 {REF} {Length: 1513} {Pfam: F5/8 type C domain [PF00754.27, score=20.0]} {RNA1509_57504} {RNA1310_27303.2} {RNA815_32964}
42. MligTC455_43741 196 4.08 Mlig455_018088

Neo: -

Age: Down-Up-Down

PTBP1 1.894 - - - 0.919 - 0.975 Mlig455_018088 {REF} {Length: 2775} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF13893.8, score=116.9]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=52.7]; Occluded RNA-recognition motif [PF16842.7, score=26.8]} {Human: ENSG00000011304, PTBP1, polypyrimidine tract binding protein 1, [Score=258, Expect=8e-80]; ENSG00000117569, PTBP2, polypyrimidine tract binding protein 2, [Score=258, Expect=1e-80]; ENSG00000119314, PTBP3, polypyrimidine tract binding protein 3, [Score=248, Expect=1e-76]} {Mouse: ENSMUSG00000028134, Ptbp2, polypyrimidine tract binding protein 2, [Score=258, Expect=7e-81]; ENSMUSG00000006498, Ptbp1, polypyrimidine tract binding protein 1, [Score=251, Expect=1e-78]; ENSMUSG00000028382, Ptbp3, polypyrimidine tract binding protein 3, [Score=248, Expect=1e-77]} {Dmel: FBgn0011224, heph, hephaestus, [Score=249, Expect=7e-78]} {Celegans: WBGene00004207, ptb-1, PTB (HnRNP) homolog; Putative RNA-binding protein PTB-1b, [Score=234, Expect=1e-72]} {Smed: dd_Smed_v6_1868_0_1, dd_Smed_v6_1868_0_1, [Score=214, Expect=4e-64]} {RNA1509_36451} {RNA1310_3345} {RNA815_23519}
43. MligTC455_47948 100 2.07 Mlig455_005840

Neo: -

Age: -

Region-enriched R2: 3.643/0.03527

TSPAN16 1.894 - - - 0.931 - 0.963 Mlig455_005840 {REF} {Length: 2130} {Pfam: Tetraspanin family [PF00335.22, score=86.4]} {Human: ENSG00000130167, TSPAN16, tetraspanin 16, [Score=48.1, Expect=6e-06]} {Mouse: ENSMUSG00000025351, Cd63, CD63 antigen, [Score=50.4, Expect=7e-07]} {Dmel: FBgn0036769, Tsp74F, Tetraspanin 74F, [Score=68.2, Expect=4e-13]} {Smed: dd_Smed_v6_854_1_1, dd_Smed_v6_854_1_1, [Score=119, Expect=5e-32]} {RNA1509_35459} {RNA1310_22253, RNA1509_35459} {RNA1509_35459, RNA815_11065}
44. MligTC455_52570 71 1.49 Mlig455_066071

Neo: -

Age: Up-Down-Up

1.894 - - - 0.909 - 0.985 Mlig455_066071 {REF} {Length: 2575} {Pfam: Hemingway/CFA97 [PF13879.8, score=54.6]; Annexin [PF00191.22, score=26.1]} {Mouse: ENSMUSG00000090336, Cfap97d2, CFAP97 domain containing 2, [Score=46.6, Expect=3e-06]} {Smed: dd_Smed_v6_2676_0_1, dd_Smed_v6_2676_0_1, [Score=70.1, Expect=2e-13]} {RNA1310_29320.1} {RNA815_54680}
45. MligTC455_16416 290 6.04 Mlig455_000468

Neo: -

Age: -

Region-enriched R2: 2.225/0.04782

ROR1 1.893 - - - 0.929 - 0.964 Mlig455_000468 {REF} {Length: 2686} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=208.1]; Protein kinase domain [PF00069.27, score=77.3]; Kringle domain [PF00051.20, score=19.4]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [Score=300, Expect=1e-89]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [Score=295, Expect=2e-87]; ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [Score=281, Expect=2e-82]} {Dmel: FBgn0010407, Ror, [Score=259, Expect=2e-76]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=217, Expect=2e-60]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [Score=328, Expect=1e-100]} {RNA1509_35395} {RNA1310_13558} {RNA815_27446}
46. MligTC455_43534 34 0.71 Mlig455_030976

Neo: -

Age: -

1.893 - - - 0.932 - 0.961 Mlig455_030976 {REF} {Length: 1067} {RNA1310_40722} {RNA815_46396}
47. MligTC455_47905 56 1.16 Mlig455_037694

Neo: -

Age: -

1.893 - - - 0.916 - 0.977 Mlig455_037694 {REF} {Length: 2503} {RNA1310_36768.1} {RNA815_27683}
48. MligTC455_47094 240 5.01 Mlig455_014204

Neo: -

Age: logFC(26M/2M)=-0.357

1.892 - - - 0.930 - 0.962 Mlig455_014204 {REF} {Length: 3346} {Smed: dd_Smed_v6_4351_0_1, dd_Smed_v6_4351_0_1, [RH, Score=238, Expect=1e-74]} {RNA1509_35661} {RNA1310_8437, RNA1509_35661} {RNA1509_35661, RNA815_15552}
49. MligTC455_20142 488 10.17 Mlig455_036513

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=-0.225

1.891 - - - 0.964 - 0.927 Mlig455_036513 {REF} {Length: 1074} {NoTransDecoderORF} {RNA1509_4350} {RNA1310_20554, RNA1509_4350} {RNA1509_4350, RNA815_8810.1}
50. MligTC455_42839 29 0.61 Mlig455_003852

Neo: -

Age: -

1.891 - - - 0.906 - 0.985 Mlig455_003852 {REF} {Length: 1047} {RNA1509_48973} {RNA1310_36721} {RNA815_36286}
51. MligTC455_45408 287 5.98 Mlig455_042398, Mlig455_042478

Neo: -

Age: logFC(26M/2M)=0.529

TNN 1.891 - - - 0.924 - 0.967

Mlig455_042398 {REF} {Length: 1857} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=124.3]; PAN domain [PF00024.28, score=19.2]} {Human: ENSG00000120332, TNN, tenascin N, [Score=98.6, Expect=3e-22]; ENSG00000160339, FCN2, ficolin 2, [Score=94.7, Expect=7e-22]} {Mouse: ENSMUSG00000026725, Tnn, tenascin N, [Score=95.9, Expect=2e-21]; ENSMUSG00000026835, Fcnb, ficolin B, [Score=95.5, Expect=2e-22]; ENSMUSG00000026938, Fcna, ficolin A, [Score=95.1, Expect=5e-22]; ENSMUSG00000028989, Angptl7, angiopoietin-like 7, [Score=91.7, Expect=7e-21]} {Dmel: FBgn0050280, CG30280, [Score=97.8, Expect=1e-23]} {Celegans: WBGene00020516, T15B7.1, [Score=65.9, Expect=6e-12]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=92.4, Expect=8e-21]} {RNA1509_43257} {RNA1310_625, RNA1509_43257} {RNA1509_43257, RNA815_271}

Mlig455_042478 {REF} {Length: 1926} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=124.2]} {Human: ENSG00000120332, TNN, tenascin N, [Score=98.2, Expect=3e-22]; ENSG00000160339, FCN2, ficolin 2, [Score=94.7, Expect=7e-22]} {Mouse: ENSMUSG00000026835, Fcnb, ficolin B, [Score=95.5, Expect=2e-22]; ENSMUSG00000026725, Tnn, tenascin N, [Score=95.5, Expect=2e-21]; ENSMUSG00000026938, Fcna, ficolin A, [Score=95.1, Expect=4e-22]; ENSMUSG00000028989, Angptl7, angiopoietin-like 7, [Score=92.0, Expect=7e-21]} {Dmel: FBgn0050280, CG30280, [Score=97.8, Expect=1e-23]} {Celegans: WBGene00020516, T15B7.1, [Score=65.9, Expect=6e-12]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=92.0, Expect=9e-21]} {RNA1509_43257} {RNA1310_625} {RNA815_271}
52. MligTC455_21756 20 0.42 Mlig455_057868

Neo: -

Age: -

1.89 - - - 0.907 - 0.983 Mlig455_057868 {REF} {Length: 1746} {Pfam: F5/8 type C domain [PF00754.27, score=36.3]} {RNA1310_33166} {RNA815_14716}
53. MligTC455_43961 30 0.62 Mlig455_027626

Neo: -

Age: -

1.89 - - - 0.907 - 0.983 Mlig455_027626 {REF} {Length: 602} {Pfam: PAN domain [PF00024.28, score=26.5]; PAN domain [PF14295.8, score=21.8]} {RNA1310_35396.1} {RNA815_23500}
54. MligTC455_50665 48 0.99 Mlig455_032812

Neo: -

Age: -

1.888 - - - 0.911 - 0.977 Mlig455_032812 {REF} {Length: 1550} {Pfam: Glycine rich protein [PF12810.9, score=23.7]} {RNA1310_48243.1} {RNA815_30313.2}
55. MligTC455_35943 122 2.55 Mlig455_062123

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.634

FEZF2 1.887 - - - 0.902 - 0.985 Mlig455_062123 {REF} {Length: 3163} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=87.7]; Zinc-finger double domain [PF13465.8, score=71.3]; C2H2-type zinc finger [PF13894.8, score=56.0]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=25.4]; Transcription factor IIA, alpha/beta subunit [PF03153.15, score=23.1]; C2H2-type zinc finger [PF13912.8, score=21.6]} {Human: ENSG00000153266, FEZF2, FEZ family zinc finger 2, [RH, Score=337, Expect=3e-107]; ENSG00000128610, FEZF1, FEZ family zinc finger 1, [RH, Score=330, Expect=6e-105]} {Mouse: ENSMUSG00000021743, Fezf2, Fez family zinc finger 2, [RH, Score=341, Expect=7e-109]; ENSMUSG00000029697, Fezf1, Fez family zinc finger 1, [RH, Score=330, Expect=1e-104]} {Dmel: FBgn0031375, erm, earmuff, [RH, Score=343, Expect=2e-107]} {Celegans: WBGene00012639, fezf-1, FEZ Family zinc finger protein, [RH, Score=293, Expect=5e-94]} {Smed: dd_Smed_v6_26394_0_1, dd_Smed_v6_26394_0_1, [RH, Score=287, Expect=9e-92]} {RNA1310_14572} {RNA815_32467}
56. MligTC455_46708 362 7.53 Mlig455_045334

Neo: -

Age: -

Region-enriched R2: 2.783/0.01800

1.887 - - - 0.905 - 0.982 Mlig455_045334 {REF} {Length: 1243} {RNA1509_51601} {RNA1310_43115.2, RNA1509_51601} {RNA1509_51601, RNA815_21402.1}
57. MligTC455_29045 127 2.65 Mlig455_056054

Neo: -

Age: -

Region-enriched R2: 4.858/0.00652

FZD5 1.886 - - - 0.902 - 0.984 Mlig455_056054 {REF} {Length: 3655} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=389.0]; Fz domain [PF01392.24, score=85.2]} {Human: ENSG00000163251, FZD5, frizzled class receptor 5, [Score=554, Expect=0.0]} {Mouse: ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [Score=561, Expect=0.0]} {Dmel: FBgn0016797, fz2, frizzled 2, [Score=516, Expect=5e-176]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=368, Expect=3e-120]} {Smed: dd_Smed_v6_16571_0_1, dd_Smed_v6_16571_0_1, [Score=522, Expect=7e-178]} {RNA1509_35313} {RNA1310_9623.1} {RNA815_2562.1}
58. MligTC455_18683 419 8.74 Mlig455_069928

Neo: -

Age: -

Region-specific R2: 6.066

Region-enriched R2: 4.921/0.00217

1.885 - - - 0.901 - 0.984 Mlig455_069928 {REF} {Length: 845} {RNA1509_25826} {RNA1310_42757} {RNA815_23874}
59. MligTC455_32445 285 5.93 Mlig455_041727, Mlig455_042282

Neo: -

Age: -

ANK2 1.884 - - - 0.955 - 0.929

Mlig455_041727 {REF} {Length: 4931} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=276.7]; Ankyrin repeats (many copies) [PF13637.8, score=238.3]; Ankyrin repeat [PF00023.32, score=223.0]; Ankyrin repeats (many copies) [PF13857.8, score=214.9]; Ankyrin repeat [PF13606.8, score=201.4]; Ion transport protein [PF00520.33, score=46.6]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=211, Expect=1e-54]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=290, Expect=2e-80]} {Dmel: FBgn0011747, Ank, Ankyrin, [Score=210, Expect=2e-54]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=489, Expect=7e-151]} {Smed: dd_Smed_v6_6201_0_2, dd_Smed_v6_6201_0_2, [RH, Score=745, Expect=0.0]} {RNA1509_18945} {RNA1310_1506.1, RNA1509_18945} {RNA1509_18945, RNA815_450.1}

Mlig455_042282 {REF} {Length: 4940} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=273.8]; Ankyrin repeats (many copies) [PF13637.8, score=232.4]; Ankyrin repeat [PF00023.32, score=218.4]; Ankyrin repeats (many copies) [PF13857.8, score=210.6]; Ankyrin repeat [PF13606.8, score=197.5]; Ion transport protein [PF00520.33, score=46.6]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=214, Expect=2e-55]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=204, Expect=1e-52]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=201, Expect=2e-51]} {Dmel: FBgn0011747, Ank, Ankyrin, [Score=205, Expect=6e-53]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=487, Expect=5e-150]} {Smed: dd_Smed_v6_6201_0_2, dd_Smed_v6_6201_0_2, [RH, Score=736, Expect=0.0]} {RNA1509_18945} {RNA1310_1506.1} {RNA815_8298}
60. MligTC455_41055 112 2.34 Mlig455_044574

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.659

Region-enriched R2: 6.247/0.00008

1.884 - - - 0.909 - 0.975 Mlig455_044574 {REF} {Length: 1203} {Smed: dd_Smed_v6_9736_0_1, dd_Smed_v6_9736_0_1, [Score=86.7, Expect=1e-20]} {RNA1509_58567} {RNA1310_87689} {RNA815_53353}
61. MligTC455_42087 129 2.68 Mlig455_028171

Neo: -

Age: -

1.884 - - - 0.905 - 0.979 Mlig455_028171 {REF} {Length: 2511} {RNA1509_40406} {RNA1310_12938} {RNA815_16887}
62. MligTC455_13963 31 0.64 Mlig455_052027

Neo: -

Age: Down-Up-Down

1.882 - - - 0.897 - 0.985 Mlig455_052027 {REF} {Length: 1717} {RNA1509_48973} {RNA1310_34931} {RNA815_59614}
63. MligTC455_29408 45 0.94 Mlig455_038322

Neo: -

Age: -

Region-enriched R2: 8.586/0.00762

MB 1.882 - - - 0.902 - 0.980 Mlig455_038322 {REF} {Length: 2059} {Pfam: Globin [PF00042.24, score=57.8]} {Human: ENSG00000198125, MB, myoglobin, [RH, Score=47.8, Expect=5e-07]} {Mouse: ENSMUSG00000018893, Mb, myoglobin, [RH, Score=45.4, Expect=2e-06]} {Celegans: WBGene00008996, glb-14, GLoBin related, [Score=51.6, Expect=4e-08]} {Smed: dd_Smed_v6_15997_0_1, dd_Smed_v6_15997_0_1, [RH, Score=63.5, Expect=1e-12]} {RNA1509_48898} {RNA1310_47695} {RNA815_7096.1}
64. MligTC455_34115 6573 136.93 Mlig455_017846, Mlig455_047865

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.581

Region-enriched R2: 4.896/0.00130

1.882 - - - 0.889 - 0.993

Mlig455_017846 {REF} {Length: 1260} {RNA1509_3560, RNA1509_36840, RNA1509_42552, RNA1509_4845, RNA1509_7701} {RNA1310_63880, RNA1509_3560, RNA1509_36840, RNA1509_42552, RNA1509_4845, RNA1509_7701} {RNA1509_3560, RNA1509_36840, RNA1509_42552, RNA1509_4845, RNA1509_7701, RNA815_12890.1}

Mlig455_047865 {REF} {Length: 1135} {RNA1509_4845} {RNA1310_63880} {RNA815_12890.1}
65. MligTC455_39180 256 5.34 Mlig455_057231

Neo: -

Age: logFC(26M/2M)=-0.449

TCTE3 1.882 - - - 0.900 - 0.982 Mlig455_057231 {REF} {Length: 1057} {Pfam: Tctex-1 family [PF03645.15, score=43.3]} {Human: ENSG00000275368, TCTE3, t-complex-associated-testis-expressed 3, [RH, Score=67.8, Expect=2e-13]; ENSG00000184786, TCTE3, t-complex-associated-testis-expressed 3, [RH, Score=67.8, Expect=2e-13]} {Mouse: ENSMUSG00000028523, Tctex1d1, Tctex1 domain containing 1, [Score=61.2, Expect=2e-11]; ENSMUSG00000079710, Gm3448, predicted gene 3448, [Score=59.3, Expect=1e-10]; ENSMUSG00000079707, Tcte3, t-complex-associated testis expressed 3, [Score=59.3, Expect=1e-10]; ENSMUSG00000116780, Gm3417, predicted gene 3417, [Score=58.5, Expect=2e-10]} {Smed: dd_Smed_v6_9036_0_1, dd_Smed_v6_9036_0_1, [Score=92.4, Expect=2e-23]} {RNA1509_34873, RNA1509_48552} {RNA1310_34743, RNA1509_34873, RNA1509_48552} {RNA1509_34873, RNA1509_48552, RNA815_18661}
66. MligTC455_37792 210 4.38 Mlig455_024774

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.926

Region-enriched R2: 6.055/0.00271

PKD1L2 1.88 - - - 0.907 - 0.973 Mlig455_024774 {REF} {Length: 6374} {Pfam: Polycystin cation channel [PF08016.14, score=224.6]; PLAT/LH2 domain [PF01477.25, score=66.8]; Ion transport protein [PF00520.33, score=30.8]} {Human: ENSG00000166473, PKD1L2, polycystin 1 like 2 (gene/pseudogene), [Score=179, Expect=9e-45]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=187, Expect=3e-47]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=109, Expect=1e-23]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [Score=187, Expect=2e-47]} {Smed: dd_Smed_v6_13975_0_1, dd_Smed_v6_13975_0_1, [Score=902, Expect=0.0]} {RNA1509_46134} {RNA1310_488} {RNA815_1711}
67. MligTC455_37793 353 7.36 Mlig455_066109, Mlig455_068663

Neo: -

Age: Up-Down-Down

HMCN1 1.88 - - - 0.899 - 0.981

Mlig455_066109 {REF} {Length: 7924} {Pfam: Thrombospondin type 1 domain [PF00090.21, score=408.1]; Spondin-like TSP1 domain [PF19028.2, score=285.5]; Polycystin cation channel [PF08016.14, score=239.7]; PLAT/LH2 domain [PF01477.25, score=86.7]; Thrombospondin type 1 domain [PF19030.2, score=78.4]; Ion transport protein [PF00520.33, score=42.7]} {Human: ENSG00000143341, HMCN1, hemicentin 1, [Score=360, Expect=8e-99]} {Mouse: ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=363, Expect=7e-100]} {Dmel: FBgn0284221, Sema5c, Semaphorin 5c, [Score=199, Expect=5e-51]} {Celegans: WBGene00000082, adt-1, ADAMTS family; ADT-1, [RH, Score=306, Expect=4e-84]} {Smed: dd_Smed_v6_13975_0_1, dd_Smed_v6_13975_0_1, [RH, Score=944, Expect=0.0]} {RNA1509_9601} {RNA1310_488} {RNA815_1711}

Mlig455_068663 {REF} {Length: 7866} {Pfam: Thrombospondin type 1 domain [PF00090.21, score=423.7]; Spondin-like TSP1 domain [PF19028.2, score=299.7]; Thrombospondin type 1 domain [PF19030.2, score=92.3]; PLAT/LH2 domain [PF01477.25, score=23.1]} {Human: ENSG00000143341, HMCN1, hemicentin 1, [Score=338, Expect=1e-94]} {Mouse: ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=341, Expect=9e-96]} {Dmel: FBgn0284221, Sema5c, Semaphorin 5c, [Score=189, Expect=2e-48]} {Celegans: WBGene00000082, adt-1, ADAMTS family; ADT-1, [RH, Score=303, Expect=2e-84]} {Smed: dd_Smed_v6_1161_0_1, dd_Smed_v6_1161_0_1, [Score=282, Expect=3e-77]} {RNA1509_9601} {RNA1310_488} {RNA815_1711}
68. MligTC455_44810 226 4.72 Mlig455_013293, Mlig455_035940, Mlig455_058406, Mlig455_058409

Neo: -

Age: -

Region-specific R2: 6.204

Region-enriched R2: 5.509/0.00501

1.88 - - - 0.901 - 0.979

Mlig455_013293 {REF} {Length: 1362} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=56.6, Expect=2e-09]} {RNA1310_28961.1} {RNA815_27532}

Mlig455_035940 {REF} {Length: 1652} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=55.8, Expect=3e-09]} {RNA1310_28961.1} {RNA815_27532}

Mlig455_058406 {REF} {Length: 991} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=55.8, Expect=4e-09]} {RNA1310_28961.1} {RNA815_27532}

Mlig455_058409 {REF} {Length: 1311} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=55.8, Expect=3e-09]} {RNA1310_28961.1} {RNA815_27532}
69. MligTC455_16874 38 0.8 Mlig455_028170

Neo: -

Age: -

KCNK18 1.878 - - - 0.894 - 0.984 Mlig455_028170 {REF} {Length: 2452} {Pfam: Ion channel [PF07885.18, score=103.1]; Protein of unknown function (DUF3112) [PF11309.10, score=20.2]} {Human: ENSG00000186795, KCNK18, potassium two pore domain channel subfamily K member 18, [Score=96.7, Expect=1e-21]} {Mouse: ENSMUSG00000040901, Kcnk18, potassium channel, subfamily K, member 18, [Score=101, Expect=2e-23]} {Dmel: FBgn0033257, sand, sandman, [Score=129, Expect=2e-33]} {Celegans: WBGene00006680, twk-28, TWiK family of potassium channels, [Score=144, Expect=3e-38]} {Smed: dd_Smed_v6_17586_0_1, dd_Smed_v6_17586_0_1, [Score=270, Expect=2e-87]} {RNA1509_39975} {RNA1310_18301.1} {RNA815_12440}
70. MligTC455_14184 23 0.48 Mlig455_026684

Neo: -

Age: -

1.876 - - - 0.923 - 0.953 Mlig455_026684 {REF} {Length: 674} {NoTransDecoderORF} {RNA1310_72508} {RNA815_40858}
71. MligTC455_16729 75 1.57 Mlig455_013762

Neo: -

Age: Up-Down-Down

Region-enriched R4: 4.685/0.03582

1.875 - - - 0.891 - 0.984 Mlig455_013762 {REF} {Length: 2706} {Pfam: Glycine rich protein [PF12810.9, score=24.7]; PAN domain [PF00024.28, score=18.7]} {RNA1310_22079} {RNA815_24304}
72. MligTC455_18506 59 1.23 Mlig455_038054

Neo: -

Age: Down-Up-Down

SP9 1.875 - - - 0.895 - 0.980 Mlig455_038054 {REF} {Length: 3168} {Pfam: Zinc-finger double domain [PF13465.8, score=49.0]; Zinc finger, C2H2 type [PF00096.28, score=40.9]; C2H2-type zinc finger [PF13894.8, score=26.8]} {Human: ENSG00000217236, SP9, Sp9 transcription factor, [RH, Score=202, Expect=4e-59]; ENSG00000164651, SP8, Sp8 transcription factor, [RH, Score=202, Expect=5e-59]} {Mouse: ENSMUSG00000068859, Sp9, trans-acting transcription factor 9, [RH, Score=202, Expect=3e-59]; ENSMUSG00000048562, Sp8, trans-acting transcription factor 8, [RH, Score=201, Expect=9e-59]} {Dmel: FBgn0020378, Sp1, [RH, Score=198, Expect=6e-56]} {Celegans: WBGene00012735, sptf-3, SP (Specificity Protein) Transcription Factor, [Score=137, Expect=1e-35]} {Smed: dd_Smed_v6_17385_0_1, dd_Smed_v6_17385_0_1, [RH, Score=160, Expect=5e-46]} {RNA1310_42373}
73. MligTC455_19042 3679 76.64 Mlig455_030661

Neo: -

Age: logFC(26M/2M)=0.480

Region-specific R2: 2.811

Region-enriched R2: 1.755/0.00003

CAV1 1.875 - - - 0.894 - 0.981 Mlig455_030661 {REF} {Length: 1257} {Pfam: Caveolin [PF01146.19, score=124.8]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=105, Expect=2e-29]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=105, Expect=2e-29]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [RH, Score=81.6, Expect=8e-20]} {Smed: dd_Smed_v6_13481_0_1, dd_Smed_v6_13481_0_1, [RH, Score=144, Expect=1e-45]} {RNA1509_52150, RNA1509_53381, RNA1509_6093, RNA1509_8522} {RNA1310_31540, RNA1509_52150, RNA1509_53381, RNA1509_6093, RNA1509_8522} {RNA1509_52150, RNA1509_53381, RNA1509_6093, RNA1509_8522, RNA815_14585}
74. MligTC455_31901 18 0.38 Mlig455_022355

Neo: -

Age: -

1.875 - - - 0.890 - 0.985 Mlig455_022355 {REF} {Length: 541} {Pfam: PAN domain [PF00024.28, score=19.0]} {RNA1310_125793} {RNA815_23776.1}
75. MligTC455_47261 1918 39.96 Mlig455_033946

Neo: -

Age: -

Region-specific R2: 4.808

Region-enriched R2: 4.545/0.00000

1.875 - - - 0.878 - 0.997 Mlig455_033946 {REF} {Length: 2098} {RNA1509_18239, RNA1509_26992, RNA1509_32368} {RNA1310_36725.1, RNA1509_18239, RNA1509_26992, RNA1509_32368} {RNA1509_18239, RNA1509_26992, RNA1509_32368, RNA815_10268.1}
76. MligTC455_09688 16 0.32 Mlig455_020078

Neo: -

Age: -

Region-enriched R5: 3.740/0.03280

1.874 - - - 0.914 - 0.960 Mlig455_020078 {REF} {Length: 803} {Pfam: WSC domain [PF01822.21, score=60.8]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=56.6, Expect=2e-09]} {RNA1509_53783} {RNA1310_40622} {RNA815_30345}
77. MligTC455_13905 34 0.71 Mlig455_023395

Neo: -

Age: -

1.874 - - - 0.920 - 0.954 Mlig455_023395 {REF} {Length: 1110} {Smed: dd_Smed_v6_12856_0_1, dd_Smed_v6_12856_0_1, [Score=47.0, Expect=2e-06]} {RNA1509_18233} {RNA1310_51675} {RNA815_25040}
78. MligTC455_29030 141 2.93 Mlig455_061986

Neo: -

Age: logFC(26M/2M)=-0.349

Region-enriched R2: 5.117/0.03372

FZD5 1.874 - - - 0.923 - 0.951 Mlig455_061986 {REF} {Length: 3701} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=386.1]; Fz domain [PF01392.24, score=95.9]} {Human: ENSG00000163251, FZD5, frizzled class receptor 5, [Score=582, Expect=0.0]} {Mouse: ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [RH, Score=586, Expect=0.0]} {Dmel: FBgn0016797, fz2, frizzled 2, [Score=545, Expect=0.0]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=388, Expect=7e-127]} {Smed: dd_Smed_v6_16571_0_1, dd_Smed_v6_16571_0_1, [RH, Score=556, Expect=0.0]} {RNA1509_35313} {RNA1310_9623.1} {RNA815_2562.1}
79. MligTC455_15450 19 0.39 Mlig455_006618

Neo: -

Age: -

1.873 - - - 0.888 - 0.985 Mlig455_006618 {REF} {Length: 653} {Pfam: WSC domain [PF01822.21, score=30.6]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=53.5, Expect=7e-09]} {RNA1310_35396.1} {RNA815_56551}
80. MligTC455_39504 298 6.2 Mlig455_017354

Neo: -

Age: -

Region-enriched R2: 2.428/0.04005

DTHD1 1.873 - - - 0.914 - 0.959 Mlig455_017354 {REF} {Length: 3800} {Pfam: Death domain [PF00531.24, score=30.4]} {Human: ENSG00000197057, DTHD1, death domain containing 1, [Score=118, Expect=1e-26]} {Mouse: ENSMUSG00000090326, Dthd1, death domain containing 1, [RH, Score=105, Expect=8e-23]} {Smed: dd_Smed_v6_13807_0_1, dd_Smed_v6_13807_0_1, [RH, Score=169, Expect=3e-43]} {RNA1509_9917} {RNA1310_4320.1} {RNA815_4192.1}
81. MligTC455_51559 43 0.89 Mlig455_002923, Mlig455_002941

Neo: -

Age: -

Region-enriched R2: 6.806/0.01463

1.873 - - - 0.888 - 0.985

Mlig455_002923 {REF} {Length: 1008} {RNA1310_77227} {RNA815_43894}

Mlig455_002941 {REF} {Length: 897} {RNA1310_88681} {RNA815_43894}
82. MligTC455_35945 130 2.71 Mlig455_065474

Neo: -

Age: Up-Down-Up

1.872 - - - 0.892 - 0.980 Mlig455_065474 {REF} {Length: 1654} {RNA1310_22530} {RNA815_54411}
83. MligTC455_36985 363 7.57 Mlig455_046905

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.516

SCNN1A 1.871 - - - 0.888 - 0.983 Mlig455_046905 {REF} {Length: 2490} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=171.1]} {Human: ENSG00000111319, SCNN1A, sodium channel epithelial 1 alpha subunit, [Score=68.6, Expect=2e-11]} {Mouse: ENSMUSG00000028008, Asic5, acid-sensing (proton-gated) ion channel family member 5, [Score=67.0, Expect=3e-11]} {Celegans: WBGene00006748, unc-8, Degenerin unc-8, [Score=58.2, Expect=1e-08]} {Smed: dd_Smed_v6_29341_0_1, dd_Smed_v6_29341_0_1, [Score=100, Expect=2e-22]} {RNA1509_33610} {RNA1310_13314.1, RNA1509_33610} {RNA1509_33610, RNA815_4277}
84. MligTC455_46880 44 0.91 Mlig455_046271

Neo: -

Age: -

IAH1 1.87 - - - 0.899 - 0.971 Mlig455_046271 {REF} {Length: 1061} {Pfam: GDSL-like Lipase/Acylhydrolase family [PF13472.8, score=75.8]; GDSL-like Lipase/Acylhydrolase [PF00657.24, score=32.0]} {Human: ENSG00000134330, IAH1, isoamyl acetate hydrolyzing esterase 1 (putative), [Score=138, Expect=2e-39]} {Mouse: ENSMUSG00000062054, Iah1, isoamyl acetate-hydrolyzing esterase 1 homolog, [Score=121, Expect=4e-33]} {Smed: dd_Smed_v6_6241_0_1, dd_Smed_v6_6241_0_1, [Score=111, Expect=8e-30]} {RNA1310_130726}
85. MligTC455_40325 103 2.15 Mlig455_013035

Neo: -

Age: -

1.869 - - - 0.885 - 0.984 Mlig455_013035 {REF} {Length: 653} {RNA1509_20946} {RNA1310_44606} {RNA815_35640}
86. MligTC455_39096 110 2.29 Mlig455_019781, Mlig455_019803

Neo: -

Age: -

1.868 - - - 0.883 - 0.985

Mlig455_019781 {REF} {Length: 1107} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=65.0]} {RNA1310_34740} {RNA815_15663}

Mlig455_019803 {REF} {Length: 1107} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=63.1]} {RNA1310_34740} {RNA815_15663}
87. MligTC455_29451 819 17.07 Mlig455_026453

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.590

LMNTD1 1.867 - - - 0.914 - 0.953 Mlig455_026453 {REF} {Length: 3415} {Pfam: Intermediate filament protein [PF00038.23, score=53.0]; Lamin Tail Domain [PF00932.21, score=40.2]; Mechanosensitive ion channel porin domain [PF12795.9, score=18.4]} {Human: ENSG00000152936, LMNTD1, lamin tail domain containing 1, [RH, Score=148, Expect=6e-38]} {Mouse: ENSMUSG00000054966, Lmntd1, lamin tail domain containing 1, [RH, Score=140, Expect=2e-35]} {Dmel: FBgn0002525, Lam, Lamin, [Score=72.4, Expect=1e-12]} {Celegans: WBGene00002051, ifa-3, Intermediate filament protein ifa-3, [Score=62.0, Expect=1e-09]} {Smed: dd_Smed_v6_10248_0_1, dd_Smed_v6_10248_0_1, [RH, Score=405, Expect=7e-127]} {RNA1509_7063} {RNA1310_3989.1} {RNA815_1147.1}
88. MligTC455_42188 714 14.88 Mlig455_004983

Neo: -

Age: -

1.867 - - - 0.914 - 0.953 Mlig455_004983 {REF} {Length: 958} {RNA1509_36666, RNA1509_48333} {RNA1310_81420, RNA1509_36666, RNA1509_48333} {RNA1509_36666, RNA1509_48333, RNA815_25950}
89. MligTC455_46394 8810 183.54 Mlig455_054818, Mlig455_054826

Neo: -

Age: -

Region-specific R2: 1.771

Region-enriched R2: 1.255/0.00038

PKD2 1.867 - - - 0.908 - 0.959

Mlig455_054818 {REF} {Length: 2992} {TRANSSPLICED} {Pfam: Polycystin cation channel [PF08016.14, score=487.7]; Ion transport protein [PF00520.33, score=93.3]; EF hand [PF00036.34, score=32.7]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=21.3]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=750, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=747, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=323, Expect=1e-96]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=380, Expect=6e-120]} {Smed: dd_Smed_v6_17348_0_3, dd_Smed_v6_17348_0_3, [Score=733, Expect=0.0]} {RNA1509_1615} {RNA1310_21296.2, RNA1509_1615} {RNA1509_1615, RNA815_3158.1}

Mlig455_054826 {REF} {Length: 3118} {TRANSSPLICED} {Pfam: Polycystin cation channel [PF08016.14, score=487.7]; Ion transport protein [PF00520.33, score=93.4]; EF hand [PF00036.34, score=32.6]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=21.2]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=754, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=751, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=323, Expect=2e-96]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=387, Expect=1e-122]} {Smed: dd_Smed_v6_13327_0_1, dd_Smed_v6_13327_0_1, [RH, Score=769, Expect=0.0]} {RNA1509_13522} {RNA1310_21296.2} {RNA815_3158.1}
90. MligTC455_50123 29 0.61 Mlig455_063710

Neo: -

Age: -

Region-enriched R4: 5.673/0.02044

1.867 - - - 0.899 - 0.968 Mlig455_063710 {REF} {Length: 1119}
91. MligTC455_52482 22 0.46 Mlig455_042671

Neo: -

Age: -

1.867 - - - 0.913 - 0.954 Mlig455_042671 {REF} {Length: 2390} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=150.1]} {Smed: dd_Smed_v6_31771_0_1, dd_Smed_v6_31771_0_1, [Score=71.2, Expect=6e-13]} {RNA1310_47540} {RNA815_16144}
92. MligTC455_16148 198 4.12 Mlig455_057689

Neo: -

Age: -

KLHDC8A 1.866 - - - 0.952 - 0.914 Mlig455_057689 {REF} {Length: 1806} {Pfam: Kelch motif [PF13964.8, score=56.9]; Kelch motif [PF01344.27, score=52.7]; Kelch motif [PF07646.17, score=37.5]; Galactose oxidase, central domain [PF13418.8, score=35.1]; Kelch motif [PF13854.8, score=27.6]} {Human: ENSG00000162873, KLHDC8A, kelch domain containing 8A, [Score=58.5, Expect=2e-09]} {Mouse: ENSMUSG00000042115, Klhdc8a, kelch domain containing 8A, [Score=63.9, Expect=1e-10]} {Smed: dd_Smed_v6_14507_0_1, dd_Smed_v6_14507_0_1, [RH, Score=209, Expect=4e-63]} {RNA1509_58319} {RNA1310_20213} {RNA815_8052}
93. MligTC455_29452 881 18.34 Mlig455_044747

Neo: -

Age: -

LMNTD1 1.865 - - - 0.913 - 0.952 Mlig455_044747 {REF} {Length: 9990} {tRNA: Phe(GAA), score=86.5} {Pfam: Intermediate filament protein [PF00038.23, score=53.6]; Lamin Tail Domain [PF00932.21, score=40.3]; Mechanosensitive ion channel porin domain [PF12795.9, score=20.9]} {Human: ENSG00000152936, LMNTD1, lamin tail domain containing 1, [RH, Score=146, Expect=3e-37]} {Mouse: ENSMUSG00000054966, Lmntd1, lamin tail domain containing 1, [RH, Score=140, Expect=3e-35]} {Dmel: FBgn0002525, Lam, Lamin, [Score=72.4, Expect=1e-12]} {Celegans: WBGene00002051, ifa-3, Intermediate filament protein ifa-3, [Score=62.8, Expect=8e-10]} {Smed: dd_Smed_v6_10248_0_1, dd_Smed_v6_10248_0_1, [Score=208, Expect=5e-56]} {RNA1509_20212} {RNA1310_1500.1} {RNA815_1147.1}
94. MligTC455_40387 28 0.59 Mlig455_019391

Neo: -

Age: Up-Down-Down

1.865 - - - 0.884 - 0.981 Mlig455_019391 {REF} {Length: 2094} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=34.2]} {Smed: dd_Smed_v6_41498_0_1, dd_Smed_v6_41498_0_1, [Score=146, Expect=1e-37]} {RNA1310_29891} {RNA815_15562}
95. MligTC455_26585 173 3.61 Mlig455_061024

Neo: -

Age: -

1.864 - - - 0.952 - 0.912 Mlig455_061024 {REF} {Length: 2825} {RNA1509_19437} {RNA1310_38787} {RNA815_16416}
96. MligTC455_41541 30 0.62 Mlig455_064895

Neo: -

Age: -

GLUL 1.864 - - - 0.883 - 0.981 Mlig455_064895 {REF} {Length: 1633} {Pfam: Glutamine synthetase, catalytic domain [PF00120.26, score=57.2]; Glutamine synthetase, beta-Grasp domain [PF03951.21, score=45.1]} {Human: ENSG00000135821, GLUL, glutamate-ammonia ligase, [RH, Score=503, Expect=4e-177]} {Mouse: ENSMUSG00000026473, Glul, glutamate-ammonia ligase (glutamine synthetase), [RH, Score=503, Expect=2e-179]} {Dmel: FBgn0001145, Gs2, Glutamine synthetase 2, [RH, Score=510, Expect=0.0]} {Celegans: WBGene00001604, gln-3, Glutamine synthetase, [RH, Score=511, Expect=0.0]} {Smed: dd_Smed_v6_896_0_1, dd_Smed_v6_896_0_1, [RH, Score=546, Expect=0.0]} {RNA1509_47000} {RNA1310_22329.1, RNA1509_47000} {RNA1509_47000, RNA815_4116.6}
97. MligTC455_43979 188 3.92 Mlig455_000082, Mlig455_063749

Neo: -

Age: -

GHSR 1.863 - - - 0.878 - 0.985

Mlig455_000082 {REF} {Length: 1342} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=53.1]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=18.2]} {Human: ENSG00000121853, GHSR, growth hormone secretagogue receptor, [Score=52.0, Expect=7e-07]} {Mouse: ENSMUSG00000051136, Ghsr, growth hormone secretagogue receptor, [Score=50.4, Expect=2e-06]} {Celegans: WBGene00018798, gnrr-1, GoNadotropin-Releasing hormone Receptor (GnRHR) related, [Score=48.9, Expect=3e-06]} {Smed: dd_Smed_v6_60346_0_1, dd_Smed_v6_60346_0_1, [RH, Score=160, Expect=9e-47]} {RNA1310_30553}

Mlig455_063749 {REF} {Length: 1323} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=48.3]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=20.4]} {Smed: dd_Smed_v6_60346_0_1, dd_Smed_v6_60346_0_1, [RH, Score=157, Expect=1e-45]} {RNA1310_30553}
98. MligTC455_26253 375 7.81 Mlig455_009976

Neo: -

Age: -

FZD5 1.862 - - - 0.877 - 0.985 Mlig455_009976 {REF} {Length: 4082} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=407.2]; Fz domain [PF01392.24, score=99.7]} {Human: ENSG00000163251, FZD5, frizzled class receptor 5, [RH, Score=605, Expect=0.0]} {Mouse: ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [RH, Score=607, Expect=0.0]} {Dmel: FBgn0016797, fz2, frizzled 2, [RH, Score=402, Expect=2e-130]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [RH, Score=417, Expect=8e-139]} {Smed: dd_Smed_v6_11823_0_1, dd_Smed_v6_11823_0_1, [RH, Score=551, Expect=0.0]} {RNA1509_25697, RNA1509_59712} {RNA1310_9946, RNA1509_25697} {RNA1509_25697, RNA815_7287}
99. MligTC455_38487 21 0.43 Mlig455_035154

Neo: -

Age: -

1.861 - - - 0.893 - 0.968 Mlig455_035154 {REF} {Length: 903} {Pfam: WSC domain [PF01822.21, score=52.5]; PAN domain [PF00024.28, score=30.4]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=47.4, Expect=5e-06]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=50.8, Expect=4e-07]} {RNA1310_44717} {RNA815_43195}
100. MligTC455_22688 18 0.37 Mlig455_030413

Neo: -

Age: -

GRIK3 1.86 - - - 0.903 - 0.957 Mlig455_030413 {REF} {Length: 3851} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=76.0]; Ligand-gated ion channel [PF00060.28, score=51.9]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=45.7]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=158, Expect=1e-40]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=153, Expect=7e-39]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=149, Expect=7e-38]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=149, Expect=6e-38]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=148, Expect=2e-37]} {Dmel: FBgn0039916, Ekar, Eye-enriched kainate receptor, [Score=142, Expect=1e-35]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=132, Expect=1e-32]} {Smed: dd_Smed_v6_4267_0_3, dd_Smed_v6_4267_0_3, [Score=149, Expect=5e-38]} {RNA1310_20394.1} {RNA815_45848}

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