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Results for MligTC455_48597

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_48597 279 5.80 Mlig455_053761

Neo: -

Age: logFC(26M/2M)=0.422

Regeneration-downregulated R6: -2.401

Regeneration-depleted R6: -2.401

 LIMA1 Mlig455_053761 {REF} {Length: 1783} {Pfam: LIM domain [PF00412.24, score=52.9]} {Human: ENSG00000050405, LIMA1, LIM domain and actin binding 1, [Score=75.1, Expect=4e-17]} {Mouse: ENSMUSG00000023022, Lima1, LIM domain and actin binding 1, [Score=73.6, Expect=1e-16]; ENSMUSG00000030470, Csrp3, cysteine and glycine-rich protein 3, [Score=70.5, Expect=2e-16]} {Dmel: FBgn0259209, Mlp60A, Muscle LIM protein at 60A, [Score=60.5, Expect=2e-13]} {Celegans: WBGene00003375, mlp-1, MLP/CRP family (Muscle LIM Protein/Cysteine-rich Protein), [Score=68.2, Expect=1e-16]} {Smed: dd_Smed_v6_537_0_1, dd_Smed_v6_537_0_1, [RH, Score=111, Expect=5e-34]} {RNA1509_38710} {RNA1310_37566} {RNA815_20664}

Cumulative graph for MligTC455_48597

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -7.045 2.991 0.03792 0.47787
RegionR2 1.53 2.991 0.04539 0.25120
RegionR3 1.267 2.991 0.07022 0.46817
RegionR4 0.479 2.991 0.60388 0.91619
RegionR5 0.691 2.991 0.41007 0.76897
RegionR6 1.628 2.991 0.01273 0.19571
RegionR7 0.554 2.991 0.57289 1.00000
RegionR8 0.896 2.991 0.38776 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.272 2.991 0.99998 1.00000
RegenerationR2 -0.464 2.991 0.21129 0.65850
RegenerationR3 -0.453 2.991 0.32814 0.75442
RegenerationR4 0.034 2.991 0.94919 1.00000
RegenerationR5 -1.002 2.991 0.04434 0.34508
RegenerationR6 -2.401 2.991 0.00004 0.00472 Specific for R6: -2.401
RegenerationBL -3.425 2.991 0.00080 0.01969
RegenerationTP 0.018 2.991 0.97797 1.00000


Genes with expression patterns similar to MligTC455_48597

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_48597 279 5.8 Mlig455_053761

Neo: -

Age: logFC(26M/2M)=0.422

Regeneration-downregulated R6: -2.401

Regeneration-depleted R6: -2.401

 LIMA1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_053761 {REF} {Length: 1783} {Pfam: LIM domain [PF00412.24, score=52.9]} {Human: ENSG00000050405, LIMA1, LIM domain and actin binding 1, [Score=75.1, Expect=4e-17]} {Mouse: ENSMUSG00000023022, Lima1, LIM domain and actin binding 1, [Score=73.6, Expect=1e-16]; ENSMUSG00000030470, Csrp3, cysteine and glycine-rich protein 3, [Score=70.5, Expect=2e-16]} {Dmel: FBgn0259209, Mlp60A, Muscle LIM protein at 60A, [Score=60.5, Expect=2e-13]} {Celegans: WBGene00003375, mlp-1, MLP/CRP family (Muscle LIM Protein/Cysteine-rich Protein), [Score=68.2, Expect=1e-16]} {Smed: dd_Smed_v6_537_0_1, dd_Smed_v6_537_0_1, [RH, Score=111, Expect=5e-34]} {RNA1509_38710} {RNA1310_37566} {RNA815_20664}
2. MligTC455_48595 503 10.48 Mlig455_017699

Neo: -

Age: -

Region-enriched R6: 1.813/0.03812

Regeneration-downregulated R6: -2.325

Regeneration-depleted R6: -2.325

 5.472 0.955 0.809 0.948 0.838 0.964 0.958 Mlig455_017699 {REF} {Length: 1875} {NoTransDecoderORF} {RNA1509_38710} {RNA1310_37566} {RNA815_20664}
3. MligTC455_51745 267 5.56 Mlig455_007920

Neo: -

Age: -

 FOXJ3 1.855 - - - - 0.978 0.877 Mlig455_007920 {REF} {Length: 2476} {Pfam: Forkhead domain [PF00250.20, score=126.3]} {Human: ENSG00000198815, FOXJ3, forkhead box J3, [RH, Score=165, Expect=4e-46]} {Mouse: ENSMUSG00000032998, Foxj3, forkhead box J3, [RH, Score=164, Expect=5e-44]} {Dmel: FBgn0004567, slp2, sloppy paired 2, [Score=118, Expect=8e-29]} {Celegans: WBGene00001434, fkh-2, ForKHead transcription factor family, [Score=115, Expect=3e-29]} {Smed: dd_Smed_v6_12170_0_1, dd_Smed_v6_12170_0_1, [RH, Score=112, Expect=2e-26]} {RNA1509_19637, RNA1509_37021, RNA1509_41082} {RNA1310_12207, RNA1509_37021, RNA1509_41082} {RNA1509_37021, RNA1509_41082, RNA815_17037}
4. MligTC455_43353 428 8.91 Mlig455_003476

Neo: -

Age: -

 1.842 0.876 - - - - 0.966 Mlig455_003476 {REF} {Length: 2887} {Smed: dd_Smed_v6_9265_0_1, dd_Smed_v6_9265_0_1, [Score=108, Expect=2e-26]} {RNA1509_49114, RNA1509_59769} {RNA1310_21358, RNA1509_49114, RNA1509_59769} {RNA1509_49114, RNA1509_59769, RNA815_21652}
5. MligTC455_19509 232 4.83 Mlig455_018973

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.427

 HMCN1 1.743 0.787 - - - 0.956 - Mlig455_018973 {REF} {Length: 4775} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=103.1]; Immunoglobulin domain [PF13927.8, score=98.9]; Immunoglobulin domain [PF13895.8, score=66.1]; Immunoglobulin domain [PF00047.27, score=49.7]; Immunoglobulin V-set domain [PF07686.19, score=40.7]} {Human: ENSG00000143341, HMCN1, hemicentin 1, [Score=95.9, Expect=1e-19]} {Mouse: ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=97.8, Expect=2e-20]} {Dmel: FBgn0284408, trol, terribly reduced optic lobes, [Score=76.6, Expect=4e-14]} {Celegans: WBGene00001863, him-4, Hemicentin; High Incidence of Males (Increased X chromosome loss), [Score=72.4, Expect=7e-13]} {Smed: dd_Smed_v6_1161_0_1, dd_Smed_v6_1161_0_1, [Score=86.3, Expect=2e-17]} {RNA1509_10174} {RNA1310_1561.1} {RNA815_4892}
6. MligTC455_43376 514 10.7 Mlig455_003642

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.256

 COL24A1 1.697 0.731 - - - 0.966 - Mlig455_003642 {REF} {Length: 4631} {Pfam: Collagen triple helix repeat (20 copies) [PF01391.20, score=485.0]; Fibrillar collagen C-terminal domain [PF01410.20, score=111.7]} {Human: ENSG00000171502, COL24A1, collagen type XXIV alpha 1 chain, [Score=370, Expect=1e-105]} {Mouse: ENSMUSG00000029661, Col1a2, collagen, type I, alpha 2, [Score=394, Expect=2e-115]} {Dmel: FBgn0000299, Col4a1, Collagen type IV alpha 1, [Score=346, Expect=1e-97]} {Celegans: WBGene00001263, emb-9, Collagen alpha-1(IV) chain, [Score=276, Expect=2e-75]} {Smed: dd_Smed_v6_8075_0_1, dd_Smed_v6_8075_0_1, [Score=473, Expect=1e-142]} {RNA1509_4709} {RNA1310_1394} {RNA815_513}
7. MligTC455_43447 167 3.48 Mlig455_029434

Neo: -

Age: -

 0.971 - - - - 0.971 - Mlig455_029434 {REF} {Length: 848} {Pfam: Family of unknown function with LKAAEAR motif [PF15478.8, score=91.2]} {Smed: dd_Smed_v6_8554_0_1, dd_Smed_v6_8554_0_1, [Score=85.9, Expect=4e-22]} {RNA1310_33601} {RNA815_52641}
8. MligTC455_29766 175 3.64 Mlig455_037897

Neo: -

Age: -

 MAP3K19 0.97 - - - - - 0.970 Mlig455_037897 {REF} {Length: 3898} {Pfam: Protein kinase domain [PF00069.27, score=188.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=135.1]; Ankyrin repeats (many copies) [PF13637.8, score=127.4]; Ankyrin repeats (3 copies) [PF12796.9, score=106.1]; Ankyrin repeats (many copies) [PF13857.8, score=78.4]; Ankyrin repeat [PF13606.8, score=47.9]; Ankyrin repeat [PF00023.32, score=33.5]; Fungal protein kinase [PF17667.3, score=25.1]; ABC1 atypical kinase-like domain [PF03109.18, score=23.4]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=159, Expect=6e-41]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=158, Expect=9e-41]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=142, Expect=7e-35]} {Celegans: WBGene00001526, gck-1, Germinal center kinase 1, [Score=131, Expect=1e-31]} {Smed: dd_Smed_v6_2030_0_16, dd_Smed_v6_2030_0_16, [Score=140, Expect=1e-35]} {RNA1509_45037} {RNA1310_17852.1} {RNA815_5323.2}
9. MligTC455_40223 172 3.59 Mlig455_016264

Neo: -

Age: -

Region-enriched R8: 3.704/0.01076

 CHRNA10 0.97 - - - - 0.970 - Mlig455_016264 {REF} {Length: 4782} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=169.5]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=109.0]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=230, Expect=2e-68]; ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=225, Expect=1e-66]} {Mouse: ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=233, Expect=9e-70]} {Dmel: FBgn0032151, nAChRalpha6, nicotinic Acetylcholine Receptor alpha6, [Score=236, Expect=2e-70]} {Celegans: WBGene00000060, acr-21, AcetylCholine Receptor, [Score=215, Expect=6e-63]} {Smed: dd_Smed_v6_31300_0_1, dd_Smed_v6_31300_0_1, [Score=280, Expect=9e-87]} {RNA1509_35668} {RNA1310_11720.1} {RNA815_6827}
10. MligTC455_17367 176 3.67 Mlig455_006862

Neo: -

Age: -

 0.962 - - - - 0.962 - Mlig455_006862 {REF} {Length: 4216} {Pfam: Ankyrin repeats (many copies) [PF13857.8, score=39.1]; Ankyrin repeats (3 copies) [PF12796.9, score=37.6]; Ankyrin repeat [PF13606.8, score=24.7]} {Celegans: WBGene00003400, dapk-1, Death-associated protein kinase dapk-1, [Score=49.3, Expect=1e-05]} {RNA1509_27330} {RNA1310_32128.2} {RNA815_16275}
11. MligTC455_24525 354 7.37 Mlig455_007869

Neo: Irradiation

Age: Up-Down-Down

Region-enriched R2: 2.053/0.02539

 MAST1 0.96 - - - - 0.960 - Mlig455_007869 {REF} {Length: 5535} {Pfam: Domain of unknown function (DUF1908) [PF08926.13, score=296.2]; Protein kinase domain [PF00069.27, score=197.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=82.3]; PDZ domain [PF17820.3, score=29.9]; PDZ domain [PF13180.8, score=23.9]; PDZ domain [PF00595.26, score=23.5]; ABC1 atypical kinase-like domain [PF03109.18, score=23.1]; Kinase-like [PF14531.8, score=18.9]} {Human: ENSG00000105613, MAST1, microtubule associated serine/threonine kinase 1, [RH, Score=696, Expect=0.0]; ENSG00000069020, MAST4, microtubule associated serine/threonine kinase family member 4, [RH, Score=687, Expect=0.0]; ENSG00000086015, MAST2, microtubule associated serine/threonine kinase 2, [RH, Score=675, Expect=0.0]} {Mouse: ENSMUSG00000053693, Mast1, microtubule associated serine/threonine kinase 1, [RH, Score=697, Expect=0.0]; ENSMUSG00000034751, Mast4, microtubule associated serine/threonine kinase family member 4, [RH, Score=682, Expect=0.0]; ENSMUSG00000003810, Mast2, microtubule associated serine/threonine kinase 2, [RH, Score=675, Expect=0.0]; ENSMUSG00000031833, Mast3, microtubule associated serine/threonine kinase 3, [RH, Score=664, Expect=0.0]; ENSMUSG00000110763, Mast3, microtubule associated serine/threonine kinase 3, [RH, Score=664, Expect=0.0]} {Dmel: FBgn0267390, dop, drop out, [RH, Score=510, Expect=3e-153]} {Celegans: WBGene00002192, kin-4, KIN-4 protein; Protein KINase, [RH, Score=563, Expect=8e-176]} {Smed: dd_Smed_v6_2028_0_1, dd_Smed_v6_2028_0_1, [RH, Score=682, Expect=0.0]} {RNA1509_37039} {RNA1310_2344.2, RNA1509_37039} {RNA1509_37039, RNA815_8686}
12. MligTC455_39207 161 3.36 Mlig455_043588

Neo: -

Age: logFC(26M/2M)=-0.502

 DCHS1 0.956 - - - - 0.956 - Mlig455_043588 {REF} {Length: 8241} {Pfam: Cadherin domain [PF00028.19, score=487.6]; Cadherin-like [PF08266.14, score=41.6]; Cadherin-like [PF16184.7, score=29.4]; RET Cadherin like domain 1 [PF17756.3, score=27.8]} {Human: ENSG00000166341, DCHS1, dachsous cadherin-related 1, [Score=391, Expect=4e-110]; ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=375, Expect=5e-105]} {Mouse: ENSMUSG00000046743, Fat4, FAT atypical cadherin 4, [Score=380, Expect=1e-106]; ENSMUSG00000036862, Dchs1, dachsous cadherin related 1, [Score=378, Expect=3e-106]} {Dmel: FBgn0284247, ds, dachsous, [Score=418, Expect=3e-119]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=201, Expect=1e-51]} {Smed: dd_Smed_v6_11744_0_1, dd_Smed_v6_11744_0_1, [Score=179, Expect=5e-45]} {RNA1509_5448} {RNA1310_281} {RNA815_2365}
13. MligTC455_52084 58 1.21 Mlig455_037061

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.495

 FAT3 0.956 - - - - 0.956 - Mlig455_037061 {REF} {Length: 9396} {Pfam: Cadherin domain [PF00028.19, score=292.6]; Laminin G domain [PF02210.26, score=96.4]; Cadherin cytoplasmic region [PF01049.19, score=79.9]; Laminin G domain [PF00054.25, score=77.6]; Cadherin-like [PF16184.7, score=57.7]; Cadherin-like [PF08266.14, score=21.5]} {Human: ENSG00000165323, FAT3, FAT atypical cadherin 3, [Score=283, Expect=2e-75]; ENSG00000282908, FAT3, FAT atypical cadherin 3, [Score=283, Expect=2e-75]} {Mouse: ENSMUSG00000074505, Fat3, FAT atypical cadherin 3, [Score=276, Expect=2e-73]; ENSMUSG00000070047, Fat1, FAT atypical cadherin 1, [Score=270, Expect=1e-71]} {Dmel: FBgn0015609, CadN, Cadherin-N, [RH, Score=719, Expect=0.0]} {Celegans: WBGene00001980, hmr-1, Cadherin-related hmr-1, [RH, Score=481, Expect=3e-136]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=177, Expect=6e-44]} {RNA1509_5439} {RNA1310_149} {RNA815_168}
14. MligTC455_54026 99 2.07 Mlig455_025843, Mlig455_025903

Neo: -

Age: -

 0.956 - - - - 0.956 -

Mlig455_025843 {REF} {Length: 2505} {TRANSSPLICED} {Pfam: Hsp20/alpha crystallin family [PF00011.23, score=91.5]; HSP20-like domain found in ArsA [PF17886.3, score=30.3]} {Dmel: FBgn0001225, Hsp26, Heat shock protein 26, [RH, Score=57.8, Expect=8e-10]} {Celegans: WBGene00008592, F08H9.4, [RH, Score=60.5, Expect=2e-11]} {Smed: dd_Smed_v6_1039_0_1, dd_Smed_v6_1039_0_1, [RH, Score=101, Expect=2e-25]} {RNA1509_26837} {RNA1310_48105} {RNA815_21766}

Mlig455_025903 {REF} {Length: 2459} {TRANSSPLICED} {Pfam: Hsp20/alpha crystallin family [PF00011.23, score=91.5]; HSP20-like domain found in ArsA [PF17886.3, score=30.3]} {Dmel: FBgn0001225, Hsp26, Heat shock protein 26, [RH, Score=57.8, Expect=8e-10]} {Celegans: WBGene00008592, F08H9.4, [RH, Score=60.8, Expect=2e-11]} {Smed: dd_Smed_v6_1039_0_1, dd_Smed_v6_1039_0_1, [RH, Score=101, Expect=2e-25]} {RNA1509_33990} {RNA1310_42388.1} {RNA815_21766}
15. MligTC455_39265 459 9.57 Mlig455_025157, Mlig455_063935

Neo: -

Age: Down-Up-Down

 PRX 0.955 - - - - 0.955 -

Mlig455_025157 {REF} {Length: 1721} {RNA1509_50938} {RNA1310_45103} {RNA815_28196.1}

Mlig455_063935 {REF} {Length: 4827} {Human: ENSG00000105227, PRX, periaxin, [Score=66.6, Expect=3e-10]} {RNA1509_50938} {RNA1310_7875} {RNA815_14212}
16. MligTC455_05969 143 2.98 Mlig455_008036, Mlig455_008076

Neo: -

Age: Up-Down-Up

 CHRM3 0.953 - - - - 0.953 -

Mlig455_008036 {REF} {Length: 4356} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=235.7]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=49.3]; Olfactory receptor [PF13853.8, score=29.1]} {Human: ENSG00000133019, CHRM3, cholinergic receptor muscarinic 3, [Score=252, Expect=3e-75]} {Mouse: ENSMUSG00000046159, Chrm3, cholinergic receptor, muscarinic 3, cardiac, [Score=248, Expect=3e-74]} {Dmel: FBgn0000037, mAChR-A, muscarinic Acetylcholine Receptor, A-type, [RH, Score=216, Expect=9e-61]} {Celegans: WBGene00001519, gar-3, Muscarinic acetylcholine receptor gar-3, [RH, Score=246, Expect=2e-73]} {Smed: dd_Smed_v6_20043_0_1, dd_Smed_v6_20043_0_1, [RH, Score=243, Expect=3e-73]} {RNA1509_25623} {RNA1310_4787.1} {RNA815_38888}

Mlig455_008076 {REF} {Length: 6010} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=260.1]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=48.6]; Olfactory receptor [PF13853.8, score=28.2]} {Human: ENSG00000133019, CHRM3, cholinergic receptor muscarinic 3, [RH, Score=306, Expect=1e-95]} {Mouse: ENSMUSG00000046159, Chrm3, cholinergic receptor, muscarinic 3, cardiac, [RH, Score=302, Expect=3e-94]} {Dmel: FBgn0000037, mAChR-A, muscarinic Acetylcholine Receptor, A-type, [RH, Score=215, Expect=4e-60]} {Celegans: WBGene00001519, gar-3, Muscarinic acetylcholine receptor gar-3, [RH, Score=307, Expect=2e-96]} {Smed: dd_Smed_v6_20043_0_1, dd_Smed_v6_20043_0_1, [RH, Score=303, Expect=1e-95]} {RNA1509_25623} {RNA1310_4787.1, RNA1509_25623} {RNA1509_25623, RNA815_17017}
17. MligTC455_13280 164 3.42 Mlig455_042501

Neo: -

Age: Down-Up-Down

 0.952 - - - - - 0.952 Mlig455_042501 {REF} {Length: 3811} {Pfam: Caspase domain [PF00656.24, score=30.2]} {RNA1509_43988} {RNA1310_8586} {RNA815_7730.1}
18. MligTC455_30140 22 0.46 Mlig455_055220

Neo: -

Age: -

 GALR2 0.952 - - - - 0.952 - Mlig455_055220 {REF} {Length: 2272} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=169.9]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=36.8]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=25.2]; Serpentine type 7TM GPCR chemoreceptor Srv [PF10323.11, score=21.8]} {Human: ENSG00000182687, GALR2, galanin receptor 2, [RH, Score=167, Expect=4e-47]} {Mouse: ENSMUSG00000020793, Galr2, galanin receptor 2, [RH, Score=164, Expect=2e-46]} {Dmel: FBgn0036789, AstC-R2, Allatostatin C receptor 2, [RH, Score=133, Expect=8e-34]} {Celegans: WBGene00013974, npr-9, Galanin-like G-protein coupled receptor npr-9, [Score=115, Expect=2e-28]} {Smed: dd_Smed_v6_10325_0_1, dd_Smed_v6_10325_0_1, [Score=142, Expect=6e-38]} {RNA1310_26096}
19. MligTC455_18501 200 4.16 Mlig455_031954

Neo: -

Age: Down-Up-Up

 0.951 - - - - - 0.951 Mlig455_031954 {REF} {Length: 1030} {RNA1509_49054} {RNA1310_32906} {RNA815_15169}
20. MligTC455_42003 140 2.91 Mlig455_022863

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.408

 GFRA3 0.95 - - - - 0.950 - Mlig455_022863 {REF} {Length: 4157} {Pfam: GDNF/GAS1 domain [PF02351.18, score=44.8]} {Human: ENSG00000146013, GFRA3, GDNF family receptor alpha 3, [RH, Score=53.9, Expect=7e-07]} {RNA1509_30984} {RNA1310_17179, RNA1509_30984} {RNA1509_30984, RNA815_27672}

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