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Results for MligTC455_48919

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_48919 343 7.14 Mlig455_004050

Neo: -

Age: logFC(26M/2M)=0.295

Region-enriched R3: 3.001/0.00120

AMY1C Mlig455_004050 {REF} {Length: 4713} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=45.5]} {Human: ENSG00000187733, AMY1C, amylase, alpha 1C (salivary), [Score=442, Expect=2e-150]; ENSG00000237763, AMY1A, amylase, alpha 1A (salivary), [Score=442, Expect=2e-150]; ENSG00000174876, AMY1B, amylase, alpha 1B (salivary), [Score=442, Expect=2e-150]; ENSG00000243480, AMY2A, amylase, alpha 2A (pancreatic), [Score=441, Expect=6e-150]; ENSG00000240038, AMY2B, amylase, alpha 2B (pancreatic), [Score=440, Expect=7e-150]} {Mouse: ENSMUSG00000074264, Amy1, amylase 1, salivary, [Score=438, Expect=3e-149]; ENSMUSG00000096569, Amy2a2, amylase 2a2, [Score=430, Expect=3e-146]; ENSMUSG00000093931, Amy2a3, amylase 2a3, [Score=430, Expect=3e-146]; ENSMUSG00000074268, Amy2a5, amylase 2a5, [Score=430, Expect=3e-146]; ENSMUSG00000096770, Amy2a4, amylase 2a4, [Score=430, Expect=3e-146]} {Dmel: FBgn0000078, Amy-d, Amylase distal, [Score=377, Expect=7e-126]} {Celegans: WBGene00008220, C50B6.7, Alpha-amylase, [Score=318, Expect=2e-100]} {RNA1509_24944} {RNA1310_6099.1, RNA1509_24944} {RNA1509_24944, RNA815_5046}

Cumulative graph for MligTC455_48919

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.301 3.417 0.72504 1.00000
RegionR2 -0.568 3.417 0.93633 1.00000
RegionR3 3.001 3.417 0.00002 0.00120
RegionR4 1.267 3.417 0.16635 0.42788
RegionR5 1.183 3.417 0.09671 0.29840
RegionR6 0.677 3.417 0.37011 0.95095
RegionR7 -5.614 3.417 0.01781 0.24516
RegionR8 -0.246 3.417 0.86758 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 3.34 3.417 0.11392 0.83847
RegenerationR2 1.74 3.417 0.05622 0.38977
RegenerationR3 0.732 3.417 0.35564 0.77367
RegenerationR4 1.269 3.417 0.15855 0.59085
RegenerationR5 0.823 3.417 0.28398 0.71254
RegenerationR6 1.717 3.417 0.03799 0.24320
RegenerationBL 2.077 3.417 0.18295 0.51235
RegenerationTP 2.829 3.417 0.15014 0.57411


Genes with expression patterns similar to MligTC455_48919

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_48919 343 7.14 Mlig455_004050

Neo: -

Age: logFC(26M/2M)=0.295

Region-enriched R3: 3.001/0.00120

AMY1C 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_004050 {REF} {Length: 4713} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=45.5]} {Human: ENSG00000187733, AMY1C, amylase, alpha 1C (salivary), [Score=442, Expect=2e-150]; ENSG00000237763, AMY1A, amylase, alpha 1A (salivary), [Score=442, Expect=2e-150]; ENSG00000174876, AMY1B, amylase, alpha 1B (salivary), [Score=442, Expect=2e-150]; ENSG00000243480, AMY2A, amylase, alpha 2A (pancreatic), [Score=441, Expect=6e-150]; ENSG00000240038, AMY2B, amylase, alpha 2B (pancreatic), [Score=440, Expect=7e-150]} {Mouse: ENSMUSG00000074264, Amy1, amylase 1, salivary, [Score=438, Expect=3e-149]; ENSMUSG00000096569, Amy2a2, amylase 2a2, [Score=430, Expect=3e-146]; ENSMUSG00000093931, Amy2a3, amylase 2a3, [Score=430, Expect=3e-146]; ENSMUSG00000074268, Amy2a5, amylase 2a5, [Score=430, Expect=3e-146]; ENSMUSG00000096770, Amy2a4, amylase 2a4, [Score=430, Expect=3e-146]} {Dmel: FBgn0000078, Amy-d, Amylase distal, [Score=377, Expect=7e-126]} {Celegans: WBGene00008220, C50B6.7, Alpha-amylase, [Score=318, Expect=2e-100]} {RNA1509_24944} {RNA1310_6099.1, RNA1509_24944} {RNA1509_24944, RNA815_5046}
2. MligTC455_48920 539 11.22 Mlig455_004019, Mlig455_004101

Neo: -

Age: logFC(26M/2M)=0.521

Region-enriched R3: 4.806/0.00011

AMY1A 5.224 0.922 0.738 0.802 0.955 0.868 0.939

Mlig455_004019 {REF} {Length: 3692} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=47.0]} {Human: ENSG00000237763, AMY1A, amylase, alpha 1A (salivary), [Score=446, Expect=4e-152]; ENSG00000174876, AMY1B, amylase, alpha 1B (salivary), [Score=446, Expect=4e-152]; ENSG00000187733, AMY1C, amylase, alpha 1C (salivary), [Score=446, Expect=4e-152]; ENSG00000243480, AMY2A, amylase, alpha 2A (pancreatic), [Score=442, Expect=9e-151]; ENSG00000240038, AMY2B, amylase, alpha 2B (pancreatic), [Score=442, Expect=1e-150]} {Mouse: ENSMUSG00000074264, Amy1, amylase 1, salivary, [Score=441, Expect=4e-150]; ENSMUSG00000096770, Amy2a4, amylase 2a4, [Score=434, Expect=1e-147]; ENSMUSG00000093931, Amy2a3, amylase 2a3, [Score=434, Expect=1e-147]; ENSMUSG00000074268, Amy2a5, amylase 2a5, [Score=434, Expect=1e-147]; ENSMUSG00000096569, Amy2a2, amylase 2a2, [Score=434, Expect=1e-147]} {Dmel: FBgn0000078, Amy-d, Amylase distal, [Score=384, Expect=2e-128]} {Celegans: WBGene00008220, C50B6.7, Alpha-amylase, [Score=319, Expect=1e-100]} {RNA1509_8491} {RNA1310_6099.1} {RNA815_5046}

Mlig455_004101 {REF} {Length: 3934} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=47.0]} {Human: ENSG00000237763, AMY1A, amylase, alpha 1A (salivary), [Score=446, Expect=4e-152]; ENSG00000174876, AMY1B, amylase, alpha 1B (salivary), [Score=446, Expect=4e-152]; ENSG00000187733, AMY1C, amylase, alpha 1C (salivary), [Score=446, Expect=4e-152]; ENSG00000243480, AMY2A, amylase, alpha 2A (pancreatic), [Score=442, Expect=9e-151]; ENSG00000240038, AMY2B, amylase, alpha 2B (pancreatic), [Score=442, Expect=1e-150]} {Mouse: ENSMUSG00000074264, Amy1, amylase 1, salivary, [Score=441, Expect=4e-150]; ENSMUSG00000096770, Amy2a4, amylase 2a4, [Score=434, Expect=1e-147]; ENSMUSG00000093931, Amy2a3, amylase 2a3, [Score=434, Expect=1e-147]; ENSMUSG00000074268, Amy2a5, amylase 2a5, [Score=434, Expect=1e-147]; ENSMUSG00000096569, Amy2a2, amylase 2a2, [Score=434, Expect=1e-147]} {Dmel: FBgn0000078, Amy-d, Amylase distal, [Score=384, Expect=2e-128]} {Celegans: WBGene00008220, C50B6.7, Alpha-amylase, [Score=319, Expect=1e-100]} {RNA1509_38912, RNA1509_8491} {RNA1310_6099.1, RNA1509_38912} {RNA1509_38912, RNA815_5046}
3. MligTC455_42352 5331 111.06 Mlig455_014325

Neo: -

Age: -

Region-enriched R3: 1.607/0.00131
Region-enriched R5: 1.102/0.02723

ACE 4.067 0.866 - 0.778 0.968 0.735 0.720 Mlig455_014325 {REF} {Length: 2705} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=705.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0016122, Acer, Angiotensin-converting enzyme-related, [RH, Score=426, Expect=4e-141]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=191, Expect=3e-51]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=411, Expect=1e-135]} {RNA1509_441, RNA1509_9027} {RNA1310_8949, RNA1509_441, RNA1509_9027} {RNA1509_441, RNA1509_9027, RNA815_4061}
4. MligTC455_30314 17741 369.6 Mlig455_014122, Mlig455_014131

Neo: -

Age: -

Region-enriched R3: 1.904/0.00059

TUBB4B 3.583 0.924 - - 0.956 0.779 0.924

Mlig455_014122 {REF} {Length: 2342} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=235.9]; Tubulin C-terminal domain [PF03953.19, score=141.7]; Misato Segment II tubulin-like domain [PF10644.11, score=24.4]} {Human: ENSG00000188229, TUBB4B, tubulin beta 4B class IVb, [RH, Score=913, Expect=0.0]} {Mouse: ENSMUSG00000036752, Tubb4b, tubulin, beta 4B class IVB, [RH, Score=913, Expect=0.0]} {Dmel: FBgn0284243, betaTub56D, beta-Tubulin at 56D, [RH, Score=854, Expect=0.0]} {Celegans: WBGene00006538, tbb-4, Tubulin beta-4 chain, [RH, Score=856, Expect=0.0]} {Smed: dd_Smed_v6_83_0_3, dd_Smed_v6_83_0_3, [RH, Score=910, Expect=0.0]} {RNA1509_24313, RNA1509_3450, RNA1509_35816, RNA1509_47714, RNA1509_5200, RNA1509_7269} {RNA1310_15130.1, RNA1509_24313, RNA1509_3450, RNA1509_35816, RNA1509_47714, RNA1509_5200, RNA1509_7269} {RNA1509_24313, RNA1509_3450, RNA1509_35816, RNA1509_47714, RNA1509_5200, RNA1509_7269, RNA815_1610.1}

Mlig455_014131 {REF} {Length: 2057} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=235.8]; Tubulin C-terminal domain [PF03953.19, score=143.3]; Misato Segment II tubulin-like domain [PF10644.11, score=24.4]} {Human: ENSG00000188229, TUBB4B, tubulin beta 4B class IVb, [RH, Score=913, Expect=0.0]} {Mouse: ENSMUSG00000036752, Tubb4b, tubulin, beta 4B class IVB, [RH, Score=913, Expect=0.0]} {Dmel: FBgn0284243, betaTub56D, beta-Tubulin at 56D, [RH, Score=854, Expect=0.0]} {Celegans: WBGene00006538, tbb-4, Tubulin beta-4 chain, [RH, Score=856, Expect=0.0]} {Smed: dd_Smed_v6_83_0_1, dd_Smed_v6_83_0_1, [RH, Score=910, Expect=0.0]} {RNA1509_10060, RNA1509_16564, RNA1509_30077, RNA1509_51924, RNA1509_5235, RNA1509_54023, RNA1509_5590, RNA1509_7735} {RNA1310_15130.1, RNA1509_10060, RNA1509_16564, RNA1509_30077, RNA1509_51924, RNA1509_5235, RNA1509_54023, RNA1509_5590, RNA1509_7735} {RNA1509_10060, RNA1509_16564, RNA1509_30077, RNA1509_51924, RNA1509_5235, RNA1509_54023, RNA1509_5590, RNA1509_7735, RNA815_1610.1}
5. MligTC455_45742 2132 44.42 Mlig455_003184, Mlig455_003387

Neo: -

Age: logFC(26M/2M)=0.345

Region-specific R4: 3.405
Region-specific R3: 3.388

Region-enriched R4: 3.484/0.00000
Region-enriched R3: 2.393/0.00000
Region-enriched R5: 1.235/0.00412

SLC22A4, SLC22A5 3.479 0.897 0.727 - 0.966 - 0.889

Mlig455_003184 {REF} {Length: 2170} {Pfam: Sugar (and other) transporter [PF00083.26, score=102.2]; Major Facilitator Superfamily [PF07690.18, score=60.9]} {Human: ENSG00000197208, SLC22A4, solute carrier family 22 member 4, [Score=274, Expect=4e-84]; ENSG00000197375, SLC22A5, solute carrier family 22 member 5, [Score=274, Expect=7e-84]} {Mouse: ENSMUSG00000063652, Slc22a21, solute carrier family 22 (organic cation transporter), member 21, [Score=278, Expect=1e-85]} {Dmel: FBgn0019952, Orct, Organic cation transporter, [Score=285, Expect=2e-88]} {Celegans: WBGene00003842, oct-1, Organic cation transporter 1, [Score=240, Expect=4e-71]} {Smed: dd_Smed_v6_10826_0_2, dd_Smed_v6_10826_0_2, [Score=198, Expect=7e-56]} {RNA1509_40645} {RNA1310_12725.1} {RNA815_4270}

Mlig455_003387 {REF} {Length: 2455} {Pfam: Sugar (and other) transporter [PF00083.26, score=70.5]; Major Facilitator Superfamily [PF07690.18, score=57.3]} {Human: ENSG00000197375, SLC22A5, solute carrier family 22 member 5, [Score=154, Expect=6e-42]; ENSG00000197208, SLC22A4, solute carrier family 22 member 4, [Score=147, Expect=2e-39]} {Mouse: ENSMUSG00000063652, Slc22a21, solute carrier family 22 (organic cation transporter), member 21, [Score=154, Expect=6e-42]} {Dmel: FBgn0019952, Orct, Organic cation transporter, [Score=174, Expect=1e-49]} {Celegans: WBGene00003843, oct-2, Organic Cation Transporter; Organic cation transporter, [Score=113, Expect=2e-27]} {Smed: dd_Smed_v6_10826_0_2, dd_Smed_v6_10826_0_2, [Score=116, Expect=1e-28]} {RNA1509_11765, RNA1509_40645} {RNA1310_12725.1, RNA1509_11765} {RNA1509_11765, RNA815_4270}
6. MligTC455_49519 17930 373.55 Mlig455_030984

Neo: -

Age: logFC(26M/2M)=0.549

Region-enriched R3: 2.084/0.00003

HPGDS 3.363 0.806 - - 0.959 0.703 0.895 Mlig455_030984 {REF} {Length: 859} {Pfam: Glutathione S-transferase, C-terminal domain [PF14497.8, score=61.6]; Glutathione S-transferase, N-terminal domain [PF02798.22, score=46.9]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=28.2]} {Human: ENSG00000163106, HPGDS, hematopoietic prostaglandin D synthase, [RH, Score=106, Expect=9e-28]} {Mouse: ENSMUSG00000029919, Hpgds, hematopoietic prostaglandin D synthase, [RH, Score=93.6, Expect=4e-23]} {Dmel: FBgn0010226, GstS1, Glutathione S transferase S1, [Score=90.1, Expect=2e-21]} {Celegans: WBGene00001753, gst-5, Probable glutathione S-transferase 5, [RH, Score=112, Expect=3e-30]} {Smed: dd_Smed_v6_20_0_1, dd_Smed_v6_20_0_1, [RH, Score=187, Expect=8e-60]} {RNA1509_12904, RNA1509_271, RNA1509_888} {RNA1310_36360, RNA1509_12904, RNA1509_888} {RNA1509_12904, RNA1509_888, RNA815_14903.1}
7. MligTC455_45590 6933 144.44 Mlig455_060243

Neo: -

Age: Up-Down-Down

Region-enriched R3: 1.918/0.00019

MRC1 3.339 0.866 0.736 - 0.950 - 0.787 Mlig455_060243 {REF} {Length: 4769} {Pfam: Lectin C-type domain [PF00059.23, score=548.8]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=62.0]; Extracellular link domain [PF00193.19, score=22.4]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [RH, Score=513, Expect=2e-156]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [RH, Score=485, Expect=1e-146]} {Dmel: FBgn0035199, tfc, triforce, [Score=57.4, Expect=8e-09]} {Celegans: WBGene00020191, clec-53, C-type LECtin, [RH, Score=103, Expect=1e-23]} {Smed: dd_Smed_v6_3193_0_2, dd_Smed_v6_3193_0_2, [Score=209, Expect=1e-54]} {RNA1509_169} {RNA1310_579} {RNA815_112.1}
8. MligTC455_24112 7326 152.63 Mlig455_006637, Mlig455_070643

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.380

CYP2D6, CYP2U1 3.333 0.852 0.800 - 0.973 0.708 -

Mlig455_006637 {REF} {Length: 1777} {Pfam: Cytochrome P450 [PF00067.24, score=343.6]} {Human: ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=263, Expect=7e-81]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [RH, Score=263, Expect=2e-81]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [RH, Score=260, Expect=2e-80]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [RH, Score=259, Expect=4e-80]; ENSG00000275211, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=2e-79]; ENSG00000283284, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=1e-79]; ENSG00000100197, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=3e-79]; ENSG00000280905, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]; ENSG00000272532, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]; ENSG00000272000, AC236040.1, cytochrome P450 family 2 subfamily D member 6 pseudogene, [RH, Score=257, Expect=4e-79]; ENSG00000282966, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]} {Mouse: ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=285, Expect=3e-90]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [RH, Score=283, Expect=1e-89]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=278, Expect=2e-87]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=273, Expect=2e-85]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=271, Expect=8e-85]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=271, Expect=1e-84]} {Dmel: FBgn0001992, Cyp303a1, [RH, Score=207, Expect=1e-60]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [RH, Score=292, Expect=3e-93]} {RNA1509_10420} {RNA1310_15091.1} {RNA815_4606.2}

Mlig455_070643 {REF} {Length: 2371} {Pfam: Cytochrome P450 [PF00067.24, score=337.1]} {Human: ENSG00000283284, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=261, Expect=1e-80]; ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=260, Expect=7e-80]; ENSG00000275211, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=260, Expect=2e-80]; ENSG00000282966, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000272000, AC236040.1, cytochrome P450 family 2 subfamily D member 6 pseudogene, [RH, Score=259, Expect=3e-80]; ENSG00000272532, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000280905, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000100197, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [RH, Score=256, Expect=6e-79]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [RH, Score=254, Expect=3e-78]} {Mouse: ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=280, Expect=2e-88]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [RH, Score=279, Expect=7e-88]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=275, Expect=3e-86]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=268, Expect=1e-83]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=268, Expect=1e-83]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=266, Expect=7e-83]} {Dmel: FBgn0001992, Cyp303a1, [RH, Score=201, Expect=4e-58]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [RH, Score=288, Expect=2e-91]} {RNA1509_10420, RNA1509_36519} {RNA1310_15091.1, RNA1509_10420, RNA1509_36519} {RNA1509_10420, RNA1509_36519, RNA815_4606.2}
9. MligTC455_19189 4042 84.21 Mlig455_062923

Neo: -

Age: -

Region-enriched R3: 1.406/0.00247

BCL2L1 3.28 0.857 0.713 - 0.750 - 0.960 Mlig455_062923 {REF} {Length: 2734} {TRANSSPLICED} {Pfam: Apoptosis regulator proteins, Bcl-2 family [PF00452.21, score=71.2]} {Human: ENSG00000171552, BCL2L1, BCL2 like 1, [RH, Score=74.7, Expect=7e-16]; ENSG00000129473, BCL2L2, BCL2 like 2, [RH, Score=73.6, Expect=2e-15]} {Mouse: ENSMUSG00000089682, Bcl2l2, BCL2-like 2, [RH, Score=77.0, Expect=6e-17]} {RNA1509_12307, RNA1509_12354, RNA1509_16411, RNA1509_21923, RNA1509_30230, RNA1509_30903, RNA1509_37262, RNA1509_41417, RNA1509_44623, RNA1509_5111, RNA1509_51616, RNA1509_6074} {RNA1310_29914, RNA1509_12307, RNA1509_12354, RNA1509_16411, RNA1509_21923, RNA1509_30230, RNA1509_30903, RNA1509_37262, RNA1509_41417, RNA1509_44623, RNA1509_5111, RNA1509_51616, RNA1509_6074} {RNA1509_12307, RNA1509_12354, RNA1509_16411, RNA1509_21923, RNA1509_30230, RNA1509_30903, RNA1509_37262, RNA1509_41417, RNA1509_44623, RNA1509_5111, RNA1509_51616, RNA1509_6074, RNA815_12873}
10. MligTC455_38362 1015 21.16 Mlig455_045508

Neo: -

Age: -

Region-enriched R4: 1.693/0.01745
Region-enriched R5: 1.163/0.02906

AADAC 3.242 0.783 - 0.730 0.965 0.764 - Mlig455_045508 {REF} {Length: 2224} {Pfam: alpha/beta hydrolase fold [PF07859.15, score=113.1]; Carboxylesterase family [PF00135.30, score=19.9]} {Human: ENSG00000114771, AADAC, arylacetamide deacetylase, [Score=96.3, Expect=2e-21]; ENSG00000197953, AADACL2, arylacetamide deacetylase like 2, [Score=93.6, Expect=2e-20]; ENSG00000261846, AADACL2, arylacetamide deacetylase like 2, [Score=93.6, Expect=2e-20]} {Mouse: ENSMUSG00000090527, Gm5538, predicted gene 5538, [Score=102, Expect=1e-23]; ENSMUSG00000095522, Gm8298, predicted gene 8298, [Score=98.2, Expect=3e-22]} {Dmel: FBgn0034491, Hsl, Hormone-sensitive lipase, [Score=65.5, Expect=4e-11]} {Celegans: WBGene00012810, nceh-1, Neutral Cholesterol Ester Hydrolase homolog, [Score=98.2, Expect=2e-22]} {Smed: dd_Smed_v6_4674_0_1, dd_Smed_v6_4674_0_1, [Score=82.0, Expect=5e-17]} {RNA1509_14307} {RNA1310_15560.2} {RNA815_8354}
11. MligTC455_48227 540 11.25 Mlig455_068078

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=2.423

Region-enriched R4: 2.853/0.00197

3.145 0.721 - 0.710 0.968 0.746 - Mlig455_068078 {REF} {Length: 1529} {Celegans: WBGene00014141, ZK899.2, [Score=48.5, Expect=2e-06]} {Smed: dd_Smed_v6_3689_0_1, dd_Smed_v6_3689_0_1, [Score=154, Expect=2e-44]} {RNA1509_42065} {RNA1310_19256} {RNA815_4158}
12. MligTC455_44699 2074 43.2 Mlig455_048395

Neo: -

Age: logFC(26M/2M)=0.553

Region-enriched R3: 1.711/0.00637

SLC10A5 2.814 0.894 - - 0.959 0.961 - Mlig455_048395 {REF} {Length: 1771} {Pfam: Sodium Bile acid symporter family [PF01758.18, score=116.4]} {Human: ENSG00000253598, SLC10A5, solute carrier family 10 member 5, [RH, Score=130, Expect=9e-33]; ENSG00000100652, SLC10A1, solute carrier family 10 member 1, [RH, Score=125, Expect=2e-31]} {Mouse: ENSMUSG00000023073, Slc10a2, solute carrier family 10, member 2, [Score=129, Expect=4e-33]; ENSMUSG00000058921, Slc10a5, solute carrier family 10 (sodium/bile acid cotransporter family), member 5, [Score=125, Expect=6e-31]; ENSMUSG00000032806, Slc10a3, solute carrier family 10 (sodium/bile acid cotransporter family), member 3, [Score=124, Expect=9e-31]} {Dmel: FBgn0030756, CG9903, [Score=103, Expect=1e-23]} {Celegans: WBGene00044650, Y71G10AR.4, [RH, Score=206, Expect=4e-60]} {Smed: dd_Smed_v6_10199_0_1, dd_Smed_v6_10199_0_1, [RH, Score=295, Expect=3e-95]} {RNA1509_51285} {RNA1310_359.1} {RNA815_3102}
13. MligTC455_45586 1555 32.4 Mlig455_039563

Neo: -

Age: Down-Up-Down

Region-enriched R3: 2.402/0.00039
Region-enriched R4: 1.652/0.04877

2.776 0.915 - - 0.907 - 0.954 Mlig455_039563 {REF} {Length: 1698} {Pfam: Ecdysteroid kinase-like family [PF02958.22, score=97.3]; Protein of unknown function (DUF1679) [PF07914.13, score=46.5]; Phosphotransferase enzyme family [PF01636.25, score=26.2]} {Dmel: FBgn0051380, CG31380, [RH, Score=49.3, Expect=3e-06]} {RNA1509_16320} {RNA1310_8890, RNA1509_16320} {RNA1509_16320, RNA815_8347}
14. MligTC455_45587 1025 21.35 Mlig455_051369

Neo: -

Age: Down-Up-Down

Region-enriched R3: 2.196/0.00000

2.751 0.833 - - 0.954 - 0.964 Mlig455_051369 {REF} {Length: 1638} {Pfam: Ecdysteroid kinase-like family [PF02958.22, score=98.4]; Protein of unknown function (DUF1679) [PF07914.13, score=50.1]; Phosphotransferase enzyme family [PF01636.25, score=28.8]} {Dmel: FBgn0051380, CG31380, [RH, Score=51.6, Expect=6e-07]} {RNA1509_16462, RNA1509_4592, RNA1509_49634} {RNA1310_8890, RNA1509_16462, RNA1509_4592, RNA1509_49634} {RNA1509_16462, RNA1509_4592, RNA1509_49634, RNA815_8347}
15. MligTC455_14370 943 19.64 Mlig455_063547

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-2.337

Region-enriched R4: 2.732/0.00256
Region-enriched R5: 2.309/0.00365
Region-enriched R3: 2.214/0.02131

CYP2C8 2.64 0.773 - - 0.951 - 0.916 Mlig455_063547 {REF} {Length: 1886} {Pfam: Cytochrome P450 [PF00067.24, score=279.9]} {Human: ENSG00000138115, CYP2C8, cytochrome P450 family 2 subfamily C member 8, [Score=262, Expect=2e-81]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [Score=256, Expect=6e-79]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [Score=249, Expect=3e-76]} {Mouse: ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [Score=259, Expect=2e-80]; ENSMUSG00000003053, Cyp2c29, cytochrome P450, family 2, subfamily c, polypeptide 29, [Score=258, Expect=4e-80]; ENSMUSG00000032808, Cyp2c38, cytochrome P450, family 2, subfamily c, polypeptide 38, [Score=258, Expect=6e-80]; ENSMUSG00000042248, Cyp2c37, cytochrome P450, family 2. subfamily c, polypeptide 37, [Score=255, Expect=7e-79]; ENSMUSG00000040660, Cyp2b9, cytochrome P450, family 2, subfamily b, polypeptide 9, [Score=253, Expect=4e-78]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [Score=252, Expect=2e-77]; ENSMUSG00000030483, Cyp2b10, cytochrome P450, family 2, subfamily b, polypeptide 10, [Score=252, Expect=2e-77]; ENSMUSG00000074254, Cyp2a4, cytochrome P450, family 2, subfamily a, polypeptide 4, [Score=252, Expect=1e-77]; ENSMUSG00000025003, Cyp2c39, cytochrome P450, family 2, subfamily c, polypeptide 39, [Score=251, Expect=3e-77]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=251, Expect=3e-77]; ENSMUSG00000054827, Cyp2c50, cytochrome P450, family 2, subfamily c, polypeptide 50, [Score=249, Expect=1e-76]; ENSMUSG00000005547, Cyp2a5, cytochrome P450, family 2, subfamily a, polypeptide 5, [Score=249, Expect=2e-76]; ENSMUSG00000049685, Cyp2g1, cytochrome P450, family 2, subfamily g, polypeptide 1, [Score=248, Expect=7e-76]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [Score=248, Expect=6e-76]; ENSMUSG00000040650, Cyp2b23, cytochrome P450, family 2, subfamily b, polypeptide 23, [Score=248, Expect=5e-76]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [Score=247, Expect=1e-75]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=202, Expect=2e-58]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [Score=215, Expect=1e-63]} {Smed: dd_Smed_v6_2351_0_2, dd_Smed_v6_2351_0_2, [Score=263, Expect=6e-82]} {RNA1509_20560} {RNA1310_19381, RNA1509_20560} {RNA1509_20560, RNA815_15513}
16. MligTC455_20134 584 12.17 Mlig455_039542

Neo: -

Age: Down-Down-Up

ATP1B2 2.629 - - - 0.969 0.888 0.772 Mlig455_039542 {REF} {Length: 1390} {Pfam: Sodium / potassium ATPase beta chain [PF00287.20, score=192.1]} {Human: ENSG00000129244, ATP1B2, ATPase Na+/K+ transporting subunit beta 2, [Score=101, Expect=5e-24]; ENSG00000101892, ATP1B4, ATPase Na+/K+ transporting family member beta 4, [Score=96.7, Expect=6e-22]} {Mouse: ENSMUSG00000041329, Atp1b2, ATPase, Na+/K+ transporting, beta 2 polypeptide, [Score=101, Expect=4e-24]; ENSMUSG00000032412, Atp1b3, ATPase, Na+/K+ transporting, beta 3 polypeptide, [Score=96.7, Expect=1e-22]} {Dmel: FBgn0015777, nrv2, nervana 2, [Score=145, Expect=2e-40]} {Celegans: WBGene00007646, nkb-1, Sodium/potassium-transporting ATPase subunit beta-1, [Score=151, Expect=1e-42]} {Smed: dd_Smed_v6_2230_0_4, dd_Smed_v6_2230_0_4, [RH, Score=213, Expect=7e-67]} {RNA1509_2976, RNA1509_59487} {RNA1310_26809, RNA1509_2976, RNA1509_59487} {RNA1509_2976, RNA1509_59487, RNA815_11848}
17. MligTC455_26883 1070 22.29 Mlig455_022052, Mlig455_062897

Neo: -

Age: Down-Down-Up

Region-enriched R3: 2.399/0.00450

B3GALT1 2.58 - - 0.845 0.965 0.770 -

Mlig455_022052 {REF} {Length: 2065} {Pfam: Galactosyltransferase [PF01762.23, score=174.2]; Fringe-like [PF02434.18, score=20.2]} {Human: ENSG00000172318, B3GALT1, beta-1,3-galactosyltransferase 1, [RH, Score=133, Expect=3e-35]; ENSG00000183778, B3GALT5, beta-1,3-galactosyltransferase 5, [RH, Score=131, Expect=1e-34]} {Mouse: ENSMUSG00000034780, B3galt1, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1, [RH, Score=133, Expect=2e-35]; ENSMUSG00000074892, B3galt5, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5, [RH, Score=129, Expect=4e-34]} {Dmel: FBgn0035558, CG11357, [RH, Score=153, Expect=3e-42]} {Celegans: WBGene00008478, E03H4.11, Hexosyltransferase, [RH, Score=91.7, Expect=3e-20]} {Smed: dd_Smed_v6_4748_0_1, dd_Smed_v6_4748_0_1, [Score=177, Expect=4e-52]} {RNA1509_15518} {RNA1310_14003, RNA1509_15518} {RNA1509_15518, RNA815_5361.1}

Mlig455_062897 {REF} {Length: 2018} {Pfam: Galactosyltransferase [PF01762.23, score=170.1]} {Human: ENSG00000172318, B3GALT1, beta-1,3-galactosyltransferase 1, [RH, Score=131, Expect=2e-34]; ENSG00000183778, B3GALT5, beta-1,3-galactosyltransferase 5, [RH, Score=129, Expect=7e-34]} {Mouse: ENSMUSG00000034780, B3galt1, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1, [RH, Score=131, Expect=1e-34]; ENSMUSG00000074892, B3galt5, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5, [RH, Score=127, Expect=2e-33]} {Dmel: FBgn0035558, CG11357, [RH, Score=152, Expect=1e-41]} {Celegans: WBGene00009849, F48F7.3, Hexosyltransferase, [RH, Score=92.0, Expect=1e-20]} {Smed: dd_Smed_v6_18077_0_1, dd_Smed_v6_18077_0_1, [RH, Score=166, Expect=1e-48]} {RNA1509_15518} {RNA1310_14003} {RNA815_5361.1}
18. MligTC455_52028 1981 41.27 Mlig455_038592

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=2.102

Region-enriched R3: 2.980/0.00000
Region-enriched R5: 1.690/0.00749

NPC2 2.567 0.880 - - - 0.733 0.954 Mlig455_038592 {REF} {Length: 867} {Pfam: ML domain [PF02221.17, score=97.1]} {Human: ENSG00000119655, NPC2, NPC intracellular cholesterol transporter 2, [RH, Score=127, Expect=6e-37]} {Mouse: ENSMUSG00000021242, Npc2, NPC intracellular cholesterol transporter 2, [Score=116, Expect=9e-34]} {Dmel: FBgn0031381, Npc2a, Niemann-Pick type C-2a, [RH, Score=128, Expect=2e-38]} {Smed: dd_Smed_v6_602_0_1, dd_Smed_v6_602_0_1, [RH, Score=129, Expect=3e-39]} {RNA1509_27769} {RNA1310_12229} {RNA815_4030}
19. MligTC455_42151 2150 44.78 Mlig455_031754

Neo: -

Age: logFC(26M/2M)=-0.411

Region-enriched R3: 1.586/0.00024
Region-enriched R4: 1.056/0.04463

2.566 0.890 - - 0.959 - 0.717 Mlig455_031754 {REF} {Length: 1956} {Pfam: Lectin C-type domain [PF00059.23, score=24.6]} {Celegans: WBGene00016619, C43H6.6, [Score=50.4, Expect=2e-06]} {RNA1509_13408, RNA1509_53962} {RNA1310_19331.1, RNA1509_53962} {RNA1509_53962, RNA815_8190.1}
20. MligTC455_37843 1027 21.4 Mlig455_036229

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.713

Region-enriched R4: 2.635/0.00618
Region-enriched R5: 2.090/0.01009

2.546 0.717 - - 0.976 - 0.853 Mlig455_036229 {REF} {Length: 3170} {RNA1509_37071} {RNA1310_75243} {RNA815_10582}
21. MligTC455_18723 1597 33.27 Mlig455_004384

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.781

Region-enriched R3: 2.164/0.00079
Region-enriched R4: 1.576/0.04930
Region-enriched R5: 1.329/0.03977

SLC3A1 2.541 0.882 - 0.706 0.953 - - Mlig455_004384 {REF} {Length: 2040} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=310.6]} {Human: ENSG00000138079, SLC3A1, solute carrier family 3 member 1, [RH, Score=371, Expect=2e-119]} {Mouse: ENSMUSG00000024131, Slc3a1, solute carrier family 3, member 1, [RH, Score=372, Expect=4e-120]} {Dmel: FBgn0002570, Mal-A1, Maltase A1, [RH, Score=384, Expect=2e-126]} {Celegans: WBGene00000224, atgp-1, Amino acid Transporter GlycoProtein subunit, [RH, Score=146, Expect=3e-37]} {Smed: dd_Smed_v6_2113_0_1, dd_Smed_v6_2113_0_1, [Score=67.8, Expect=8e-12]} {RNA1509_19345} {RNA1310_12682.1} {RNA815_15968}
22. MligTC455_18724 1612 33.59 Mlig455_037198

Neo: -

Age: -

Region-enriched R3: 2.022/0.00141

SLC3A1 2.541 0.882 - 0.706 0.953 - - Mlig455_037198 {REF} {Length: 2052} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=311.9]} {Human: ENSG00000138079, SLC3A1, solute carrier family 3 member 1, [RH, Score=373, Expect=2e-120]} {Mouse: ENSMUSG00000024131, Slc3a1, solute carrier family 3, member 1, [RH, Score=374, Expect=5e-121]} {Dmel: FBgn0002570, Mal-A1, Maltase A1, [RH, Score=385, Expect=1e-126]} {Celegans: WBGene00000225, atgp-2, Amino acid Transporter GlycoProtein subunit, [RH, Score=147, Expect=2e-37]} {Smed: dd_Smed_v6_2113_0_1, dd_Smed_v6_2113_0_1, [Score=67.8, Expect=9e-12]} {RNA1509_14094, RNA1509_15182, RNA1509_19345} {RNA1310_12682.1, RNA1509_14094, RNA1509_15182, RNA1509_19345} {RNA1509_14094, RNA1509_15182, RNA1509_19345, RNA815_15968}
23. MligTC455_45090 767 15.97 Mlig455_050942

Neo: -

Age: Down-Up-Down

Region-enriched R3: 1.666/0.00039
Region-enriched R4: 1.435/0.01328

NAAA 2.54 0.818 - 0.767 0.955 - - Mlig455_050942 {REF} {Length: 1563} {Pfam: beta subunit of N-acylethanolamine-hydrolyzing acid amidase [PF15508.8, score=40.2]; Linear amide C-N hydrolases, choloylglycine hydrolase family [PF02275.20, score=40.0]} {Human: ENSG00000138744, NAAA, N-acylethanolamine acid amidase, [RH, Score=243, Expect=5e-77]} {Mouse: ENSMUSG00000029413, Naaa, N-acylethanolamine acid amidase, [RH, Score=248, Expect=7e-79]} {Celegans: WBGene00021917, Y55D5A.3, [RH, Score=198, Expect=5e-60]} {RNA1509_56673} {RNA1310_22544, RNA1509_56673} {RNA1509_56673, RNA815_9551.1}
24. MligTC455_43692 1533 31.94 Mlig455_010960

Neo: Irradiation

Age: -

Region-specific R4: 4.173

Region-enriched R4: 2.690/0.00000

Regeneration-downregulated R4: -2.347

Regeneration-depleted R4: -2.347

ABCG4 2.534 - - - 0.953 0.768 0.813 Mlig455_010960 {REF} {Length: 1261} {Pfam: ABC-2 type transporter [PF01061.26, score=140.7]} {Human: ENSG00000172350, ABCG4, ATP binding cassette subfamily G member 4, [Score=125, Expect=6e-31]} {Mouse: ENSMUSG00000032131, Abcg4, ATP binding cassette subfamily G member 4, [Score=123, Expect=2e-30]} {Dmel: FBgn0003996, w, white, [Score=273, Expect=2e-85]} {Celegans: WBGene00015479, wht-1, ABC transporter ATP-binding protein/permease wht-1, [Score=219, Expect=6e-66]} {Smed: dd_Smed_v6_8560_0_1, dd_Smed_v6_8560_0_1, [RH, Score=266, Expect=8e-83]} {RNA1509_6339, RNA1509_6662} {RNA1310_1122.2, RNA1509_6339, RNA1509_6662} {RNA1509_6339, RNA1509_6662, RNA815_3368}
25. MligTC455_37239 1846 38.46 Mlig455_060082

Neo: -

Age: -

Region-enriched R3: 1.562/0.04763
Region-enriched R5: 1.292/0.04648

PANK4 2.502 0.793 - 0.743 0.966 - - Mlig455_060082 {REF} {Length: 1532} {Pfam: Fumble [PF03630.16, score=120.5]} {Human: ENSG00000273494, PANK4, pantothenate kinase 4, [Score=106, Expect=2e-24]; ENSG00000157881, PANK4, pantothenate kinase 4, [Score=106, Expect=2e-24]} {Mouse: ENSMUSG00000029056, Pank4, pantothenate kinase 4, [Score=97.4, Expect=1e-21]} {Dmel: FBgn0011205, fbl, fumble, [Score=66.2, Expect=7e-12]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [Score=170, Expect=1e-49]} {RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233} {RNA1310_20224, RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233} {RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233, RNA815_7673}
26. MligTC455_48834 1469 30.61 Mlig455_056292

Neo: -

Age: -

Regeneration-downregulated BL: -2.291

Regeneration-depleted BL: -2.291

SFRP2 2.49 - - - 0.951 0.811 0.728 Mlig455_056292 {REF} {Length: 1997} {TRANSSPLICED} {Pfam: Fz domain [PF01392.24, score=92.7]} {Human: ENSG00000145423, SFRP2, secreted frizzled related protein 2, [Score=147, Expect=8e-41]; ENSG00000120057, SFRP5, secreted frizzled related protein 5, [Score=142, Expect=8e-39]} {Mouse: ENSMUSG00000027996, Sfrp2, secreted frizzled-related protein 2, [Score=148, Expect=4e-41]; ENSMUSG00000018822, Sfrp5, secreted frizzled-related sequence protein 5, [Score=142, Expect=6e-39]} {Dmel: FBgn0027342, fz4, frizzled 4, [Score=95.5, Expect=7e-21]} {Celegans: WBGene00022242, sfrp-1, Secreted Frizzled-Related Protein, [Score=150, Expect=4e-42]} {Smed: dd_Smed_v6_13985_0_1, dd_Smed_v6_13985_0_1, [Score=155, Expect=9e-44]} {RNA1509_25024, RNA1509_36877, RNA1509_4380} {RNA1310_12829.1, RNA1509_25024, RNA1509_36877, RNA1509_4380} {RNA1509_25024, RNA1509_36877, RNA1509_4380, RNA815_4718}
27. MligTC455_34547 437 9.11 Mlig455_052252

Neo: -

Age: -

Region-enriched R3: 2.304/0.02662

2.457 0.770 0.720 - 0.967 - - Mlig455_052252 {REF} {Length: 1475} {RNA1509_4906} {RNA1310_88.1} {RNA815_214}
28. MligTC455_34548 892 18.58 Mlig455_037149, Mlig455_052297

Neo: -

Age: Up-Down-Down

Region-enriched R3: 1.952/0.03060

2.455 0.771 0.719 - 0.965 - -

Mlig455_037149 {REF} {Length: 10460} {TRANSSPLICED} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=31.2]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=55.8, Expect=5e-07]} {RNA1509_40938, RNA1509_4906} {RNA1310_88.1, RNA1509_40938} {RNA1509_40938, RNA815_214}

Mlig455_052297 {REF} {Length: 9432} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=36.3]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=52.0, Expect=7e-06]} {RNA1509_4906} {RNA1310_88.1} {RNA815_214}
29. MligTC455_18923 743 15.48 Mlig455_063038

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-1.791

Region-enriched R4: 2.273/0.01537

2.453 0.729 - - 0.955 0.769 - Mlig455_063038 {REF} {Length: 1906} {RNA1509_26120} {RNA1310_29982} {RNA815_3607}
30. MligTC455_52041 2170 45.21 Mlig455_029621

Neo: -

Age: logFC(26M/2M)=0.515

Region-enriched R3: 1.780/0.00221
Region-enriched R5: 1.483/0.00437

SCIN 2.432 0.747 - 0.721 0.964 - - Mlig455_029621 {REF} {Length: 1419} {Pfam: Gelsolin repeat [PF00626.24, score=61.4]} {Human: ENSG00000006747, SCIN, scinderin, [Score=78.6, Expect=3e-15]} {Mouse: ENSMUSG00000002565, Scin, scinderin, [Score=82.8, Expect=7e-17]} {Dmel: FBgn0010225, Gel, Gelsolin, [Score=76.6, Expect=7e-15]} {Smed: dd_Smed_v6_1215_0_1, dd_Smed_v6_1215_0_1, [Score=214, Expect=8e-67]} {RNA1509_17911} {RNA1310_15610} {RNA815_7841}
31. MligTC455_52040 2198 45.8 Mlig455_029597

Neo: Germline

Age: logFC(26M/2M)=0.256

Region-enriched R3: 1.723/0.00072
Region-enriched R5: 1.481/0.00114

VIL1 2.428 0.743 - 0.720 0.965 - - Mlig455_029597 {REF} {Length: 2577} {Pfam: Gelsolin repeat [PF00626.24, score=113.7]} {Human: ENSG00000127831, VIL1, villin 1, [Score=182, Expect=5e-53]; ENSG00000148180, GSN, gelsolin, [Score=179, Expect=1e-49]; ENSG00000135407, AVIL, advillin, [Score=174, Expect=1e-47]} {Mouse: ENSMUSG00000026879, Gsn, gelsolin, [Score=185, Expect=7e-52]; ENSMUSG00000026175, Vil1, villin 1, [Score=182, Expect=1e-50]} {Dmel: FBgn0010225, Gel, Gelsolin, [Score=194, Expect=3e-55]} {Celegans: WBGene00010593, gsnl-1, Gelsolin-like protein 1, [Score=164, Expect=4e-46]} {Smed: dd_Smed_v6_1215_0_1, dd_Smed_v6_1215_0_1, [RH, Score=403, Expect=3e-140]} {RNA1509_12411, RNA1509_17911, RNA1509_2858, RNA1509_30271, RNA1509_44412, RNA1509_44633} {RNA1310_15610, RNA1509_12411, RNA1509_17911, RNA1509_2858, RNA1509_30271, RNA1509_44412, RNA1509_44633} {RNA1509_12411, RNA1509_17911, RNA1509_2858, RNA1509_30271, RNA1509_44412, RNA1509_44633, RNA815_7841}
32. MligTC455_48071 1712 35.67 Mlig455_048082

Neo: -

Age: logFC(26M/2M)=-0.321

Region-enriched R4: 1.489/0.04451

HSD11B1 2.427 0.754 0.715 - 0.958 - - Mlig455_048082 {REF} {Length: 1293} {Pfam: short chain dehydrogenase [PF00106.27, score=123.3]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=75.2]; KR domain [PF08659.12, score=26.1]} {Human: ENSG00000117594, HSD11B1, hydroxysteroid 11-beta dehydrogenase 1, [Score=155, Expect=4e-45]} {Mouse: ENSMUSG00000016194, Hsd11b1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=150, Expect=1e-43]} {Dmel: FBgn0027583, CG7601, [Score=82.4, Expect=9e-18]} {Celegans: WBGene00000982, dhs-19, DeHydrogenases, Short chain, [Score=73.2, Expect=1e-14]} {Smed: dd_Smed_v6_4976_0_1, dd_Smed_v6_4976_0_1, [Score=62.8, Expect=3e-11]} {RNA1509_14549, RNA1509_28912} {RNA1310_26648, RNA1509_14549, RNA1509_28912} {RNA1509_14549, RNA1509_28912, RNA815_11342}
33. MligTC455_43756 3225 67.19 Mlig455_010402

Neo: -

Age: -

Region-enriched R3: 1.722/0.00762

1.854 0.890 - - 0.964 - - Mlig455_010402 {REF} {Length: 2001} {Pfam: Innexin [PF00876.20, score=339.7]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=100, Expect=3e-23]} {Celegans: WBGene00006749, unc-9, Innexin unc-9, [Score=291, Expect=2e-95]} {Smed: dd_Smed_v6_734_0_2, dd_Smed_v6_734_0_2, [Score=292, Expect=3e-95]} {RNA1509_21594, RNA1509_22136, RNA1509_30214, RNA1509_32964, RNA1509_3943, RNA1509_49855} {RNA1310_16777, RNA1509_21594, RNA1509_22136, RNA1509_30214, RNA1509_32964, RNA1509_3943, RNA1509_49855} {RNA1509_21594, RNA1509_22136, RNA1509_30214, RNA1509_32964, RNA1509_3943, RNA1509_49855, RNA815_7295}
34. MligTC455_48226 475 9.89 Mlig455_006039

Neo: -

Age: logFC(26M/2M)=0.772

Region-enriched R4: 2.063/0.02194
Region-enriched R3: 1.959/0.00629

1.851 - - 0.862 0.989 - - Mlig455_006039 {REF} {Length: 3886} {Celegans: WBGene00014141, ZK899.2, [RH, Score=145, Expect=5e-39]} {Smed: dd_Smed_v6_3689_0_1, dd_Smed_v6_3689_0_1, [RH, Score=360, Expect=2e-122]} {RNA1509_34003, RNA1509_40119, RNA1509_42065} {RNA1310_14532, RNA1509_34003, RNA1509_40119, RNA1509_42065} {RNA1509_34003, RNA1509_40119, RNA1509_42065, RNA815_4158}
35. MligTC455_35217 5138 107.05 Mlig455_014282, Mlig455_014335

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.399

Region-enriched R3: 1.348/0.01129

1.832 0.880 - - 0.952 - -

Mlig455_014282 {REF} {Length: 1807} {TRANSSPLICED} {Pfam: Transferase family [PF02458.17, score=158.0]} {RNA1509_22501, RNA1509_4768} {RNA1310_7742.1, RNA1509_22501} {RNA1509_22501, RNA815_6411}

Mlig455_014335 {REF} {Length: 1769} {TRANSSPLICED} {Pfam: Transferase family [PF02458.17, score=159.5]} {RNA1509_4768} {RNA1310_7742.1} {RNA815_6411}
36. MligTC455_39889 2060 42.92 Mlig455_033747

Neo: -

Age: -

GDPD1 1.831 0.851 - - 0.980 - - Mlig455_033747 {REF} {Length: 1632} {Pfam: Glycerophosphoryl diester phosphodiesterase family [PF03009.19, score=130.1]} {Human: ENSG00000153982, GDPD1, glycerophosphodiester phosphodiesterase domain containing 1, [Score=57.4, Expect=4e-09]} {Mouse: ENSMUSG00000061666, Gdpd1, glycerophosphodiester phosphodiesterase domain containing 1, [Score=55.1, Expect=4e-08]} {Celegans: WBGene00021497, Y40C5A.4, [RH, Score=53.9, Expect=5e-08]} {RNA1509_4963, RNA1509_55034, RNA1509_9150} {RNA1310_11037, RNA1509_4963, RNA1509_55034, RNA1509_9150} {RNA1509_4963, RNA1509_55034, RNA1509_9150, RNA815_4734}
37. MligTC455_38469 2237 46.61 Mlig455_028190, Mlig455_063554

Neo: -

Age: logFC(26M/2M)=0.551

Region-enriched R4: 2.765/0.00002
Region-enriched R3: 2.517/0.00000
Region-enriched R5: 1.859/0.00156

MFSD2A 1.827 0.874 - - 0.953 - -

Mlig455_028190 {REF} {Length: 1877} {Pfam: MFS/sugar transport protein [PF13347.8, score=314.5]; Major Facilitator Superfamily [PF07690.18, score=35.3]} {Human: ENSG00000168389, MFSD2A, major facilitator superfamily domain containing 2A, [RH, Score=317, Expect=2e-101]} {Mouse: ENSMUSG00000028655, Mfsd2a, major facilitator superfamily domain containing 2A, [RH, Score=312, Expect=2e-99]} {Smed: dd_Smed_v6_11210_0_1, dd_Smed_v6_11210_0_1, [RH, Score=380, Expect=3e-126]} {RNA1509_5264} {RNA1310_14549} {RNA815_5531}

Mlig455_063554 {REF} {Length: 2339} {Pfam: MFS/sugar transport protein [PF13347.8, score=217.9]; Major Facilitator Superfamily [PF07690.18, score=39.9]} {Human: ENSG00000168389, MFSD2A, major facilitator superfamily domain containing 2A, [RH, Score=223, Expect=1e-68]} {Mouse: ENSMUSG00000037336, Mfsd2b, major facilitator superfamily domain containing 2B, [RH, Score=212, Expect=2e-64]} {Smed: dd_Smed_v6_11210_0_1, dd_Smed_v6_11210_0_1, [Score=274, Expect=8e-87]} {RNA1509_5264} {RNA1310_14549} {RNA815_5531}
38. MligTC455_53528 378 7.87 Mlig455_040364

Neo: -

Age: logFC(26M/2M)=0.734

Region-enriched R4: 3.457/0.00234
Region-enriched R3: 2.972/0.00183

1.825 0.867 - - 0.958 - - Mlig455_040364 {REF} {Length: 1576} {TRANSSPLICED} {Pfam: Universal stress protein family [PF00582.28, score=97.2]} {Smed: dd_Smed_v6_985_0_1, dd_Smed_v6_985_0_1, [RH, Score=119, Expect=9e-35]} {RNA1509_7232} {RNA1310_49135, RNA1509_7232} {RNA1509_7232, RNA815_18182.1}
39. MligTC455_48070 1559 32.49 Mlig455_019661

Neo: -

Age: logFC(26M/2M)=-0.328

Region-enriched R3: 1.615/0.01457

HSD11B1 1.811 0.828 - - 0.983 - - Mlig455_019661 {REF} {Length: 1828} {Pfam: short chain dehydrogenase [PF00106.27, score=125.5]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=75.3]; KR domain [PF08659.12, score=27.1]} {Human: ENSG00000117594, HSD11B1, hydroxysteroid 11-beta dehydrogenase 1, [Score=157, Expect=2e-45]} {Mouse: ENSMUSG00000016194, Hsd11b1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=154, Expect=1e-44]} {Dmel: FBgn0027583, CG7601, [Score=82.0, Expect=1e-17]} {Celegans: WBGene00014093, ZK829.1, [Score=74.3, Expect=4e-15]} {Smed: dd_Smed_v6_3167_0_1, dd_Smed_v6_3167_0_1, [Score=62.8, Expect=2e-11]} {RNA1509_11335, RNA1509_15148} {RNA1310_26648, RNA1509_11335, RNA1509_15148} {RNA1509_11335, RNA1509_15148, RNA815_11342}
40. MligTC455_37844 379 7.9 Mlig455_036230

Neo: -

Age: -

Region-enriched R4: 5.818/0.00000
Region-enriched R5: 2.587/0.03402

1.804 - - - 0.956 0.848 - Mlig455_036230 {REF} {Length: 331} {NoTransDecoderORF} {RNA1509_37071} {RNA1310_16369} {RNA815_10582}
41. MligTC455_23305 524 10.91 Mlig455_054093

Neo: -

Age: -

Region-enriched R3: 1.848/0.00073
Region-enriched R4: 1.814/0.00794

CH25H 1.794 - - - 0.962 0.832 - Mlig455_054093 {REF} {Length: 2052} {Pfam: Fatty acid hydroxylase superfamily [PF04116.15, score=77.6]} {Human: ENSG00000138135, CH25H, cholesterol 25-hydroxylase, [RH, Score=168, Expect=7e-50]} {Mouse: ENSMUSG00000050370, Ch25h, cholesterol 25-hydroxylase, [RH, Score=182, Expect=3e-55]} {Celegans: WBGene00018036, F35C8.5, Cholesterol 25-hydroxylase-like protein, [RH, Score=199, Expect=6e-62]} {RNA1509_13990, RNA1509_16293, RNA1509_2104} {RNA1310_8947, RNA1509_13990, RNA1509_16293, RNA1509_2104} {RNA1509_13990, RNA1509_16293, RNA1509_2104, RNA815_835.1}
42. MligTC455_51925 253 5.27 Mlig455_009245

Neo: -

Age: Down-Up-Down

Region-enriched R5: 1.320/0.02123

UGCG 1.793 - - - 0.969 0.824 - Mlig455_009245 {REF} {Length: 3283} {Pfam: Glycosyl transferase family 21 [PF13506.8, score=148.2]; Glycosyltransferase like family 2 [PF13641.8, score=73.9]; Glycosyl transferase family group 2 [PF13632.8, score=41.9]} {Human: ENSG00000148154, UGCG, UDP-glucose ceramide glucosyltransferase, [Score=301, Expect=5e-99]} {Mouse: ENSMUSG00000028381, Ugcg, UDP-glucose ceramide glucosyltransferase, [Score=306, Expect=4e-101]} {Dmel: FBgn0067102, GlcT-1, Ceramide glucosyltransferase, [Score=317, Expect=1e-104]} {Celegans: WBGene00019127, cgt-3, Ceramide glucosyltransferase 3, [RH, Score=293, Expect=4e-95]} {Smed: dd_Smed_v6_2757_0_1, dd_Smed_v6_2757_0_1, [RH, Score=291, Expect=1e-94]} {RNA1509_16764, RNA1509_43390} {RNA1310_8682.2, RNA1509_16764, RNA1509_43390} {RNA1509_16764, RNA1509_43390, RNA815_2800}
43. MligTC455_27557 429 8.93 Mlig455_022499

Neo: -

Age: -

1.786 - 0.822 - 0.964 - - Mlig455_022499 {REF} {Length: 2413} {RNA1509_15552} {RNA1310_15792} {RNA815_5911}
44. MligTC455_41283 1026 21.38 Mlig455_056291

Neo: -

Age: Down-Up-Up

Region-enriched R3: 2.480/0.00000
Region-enriched R4: 1.642/0.01172
Region-enriched R5: 1.330/0.01324

1.786 0.957 - - 0.829 - - Mlig455_056291 {REF} {Length: 1075} {RNA1509_3034} {RNA1310_55537, RNA1509_3034} {RNA1509_3034, RNA815_28451}
45. MligTC455_49840 1487 30.98 Mlig455_054770, Mlig455_054797

Neo: -

Age: -

Region-enriched R3: 1.670/0.00009
Region-enriched R5: 1.605/0.00002
Region-enriched R4: 1.351/0.01428

ECE1 1.767 - - - 0.954 0.813 -

Mlig455_054770 {REF} {Length: 3217} {Pfam: Peptidase family M13 [PF05649.15, score=200.5]; Peptidase family M13 [PF01431.23, score=91.3]} {Human: ENSG00000117298, ECE1, endothelin converting enzyme 1, [Score=179, Expect=1e-46]; ENSG00000142606, MMEL1, membrane metalloendopeptidase like 1, [Score=177, Expect=1e-45]; ENSG00000277131, MMEL1, membrane metalloendopeptidase like 1, [Score=177, Expect=1e-45]; ENSG00000171551, ECEL1, endothelin converting enzyme like 1, [Score=174, Expect=7e-45]} {Mouse: ENSMUSG00000058183, Mmel1, membrane metallo-endopeptidase-like 1, [Score=190, Expect=2e-50]} {Dmel: FBgn0029843, Nep1, Neprilysin 1, [Score=182, Expect=2e-47]} {Celegans: WBGene00020230, nep-2, Neprilysin-2, [Score=154, Expect=9e-39]} {Smed: dd_Smed_v6_1910_0_1, dd_Smed_v6_1910_0_1, [Score=160, Expect=7e-41]} {RNA1509_3125} {RNA1310_4911.1, RNA1509_3125} {RNA1509_3125, RNA815_2994}

Mlig455_054797 {REF} {Length: 3127} {Pfam: Peptidase family M13 [PF05649.15, score=200.5]; Peptidase family M13 [PF01431.23, score=92.9]} {Human: ENSG00000117298, ECE1, endothelin converting enzyme 1, [Score=182, Expect=2e-47]; ENSG00000142606, MMEL1, membrane metalloendopeptidase like 1, [Score=179, Expect=1e-46]; ENSG00000277131, MMEL1, membrane metalloendopeptidase like 1, [Score=179, Expect=1e-46]; ENSG00000171551, ECEL1, endothelin converting enzyme like 1, [Score=177, Expect=1e-45]; ENSG00000196549, MME, membrane metalloendopeptidase, [Score=173, Expect=1e-44]} {Mouse: ENSMUSG00000058183, Mmel1, membrane metallo-endopeptidase-like 1, [Score=193, Expect=2e-51]} {Dmel: FBgn0029843, Nep1, Neprilysin 1, [Score=184, Expect=3e-48]} {Celegans: WBGene00020230, nep-2, Neprilysin-2, [Score=157, Expect=1e-39]} {Smed: dd_Smed_v6_1910_0_1, dd_Smed_v6_1910_0_1, [Score=163, Expect=8e-42]} {RNA1509_3125} {RNA1310_4911.1} {RNA815_2994}
46. MligTC455_40294 928 19.33 Mlig455_062769

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.415

Region-enriched R4: 2.693/0.00000
Region-enriched R3: 1.531/0.00694
Region-enriched R5: 1.366/0.00671

VAV1 1.752 0.788 - - 0.964 - - Mlig455_062769 {REF} {Length: 4319} {Pfam: SH2 domain [PF00017.26, score=34.9]; RhoGEF domain [PF00621.22, score=28.2]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=27.1]} {Human: ENSG00000141968, VAV1, vav guanine nucleotide exchange factor 1, [Score=93.6, Expect=5e-19]} {Mouse: ENSMUSG00000034116, Vav1, vav 1 oncogene, [Score=91.3, Expect=1e-18]} {Dmel: FBgn0040068, Vav, Vav guanine nucleotide exchange factor, [Score=61.2, Expect=2e-09]} {Celegans: WBGene00006887, vav-1, [Score=64.3, Expect=2e-10]} {RNA1509_11835} {RNA1310_8757} {RNA815_2576}
47. MligTC455_49771 61 1.26 Mlig455_018423

Neo: -

Age: -

1.75 0.796 - - 0.954 - - Mlig455_018423 {REF} {Length: 2813} {RNA1509_25822} {RNA1310_57791} {RNA815_29848}
48. MligTC455_40293 973 20.27 Mlig455_003116

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.598

Region-enriched R4: 2.611/0.00000
Region-enriched R3: 1.603/0.00240
Region-enriched R5: 1.400/0.00374

VAV1 1.747 0.786 - - 0.961 - - Mlig455_003116 {REF} {Length: 5727} {Pfam: SH2 domain [PF00017.26, score=32.8]; RhoGEF domain [PF00621.22, score=31.4]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=27.4]} {Human: ENSG00000141968, VAV1, vav guanine nucleotide exchange factor 1, [Score=95.1, Expect=2e-19]} {Mouse: ENSMUSG00000034116, Vav1, vav 1 oncogene, [Score=92.0, Expect=1e-18]} {Dmel: FBgn0040068, Vav, Vav guanine nucleotide exchange factor, [Score=65.1, Expect=2e-10]} {Celegans: WBGene00006887, vav-1, [Score=65.5, Expect=9e-11]} {RNA1509_11835} {RNA1310_8757} {RNA815_2576}
49. MligTC455_42224 691 14.4 Mlig455_012381, Mlig455_012802

Neo: -

Age: logFC(26M/2M)=-0.411

Region-enriched R4: 3.746/0.00086
Region-enriched R3: 3.098/0.00277

ENTPD6 1.745 - - - 0.962 - 0.783

Mlig455_012381 {REF} {Length: 2018} {Pfam: GDA1/CD39 (nucleoside phosphatase) family [PF01150.19, score=209.9]; Ppx/GppA phosphatase family [PF02541.18, score=18.1]} {Human: ENSG00000197586, ENTPD6, ectonucleoside triphosphate diphosphohydrolase 6 (putative), [Score=196, Expect=9e-57]} {Mouse: ENSMUSG00000033068, Entpd6, ectonucleoside triphosphate diphosphohydrolase 6, [Score=196, Expect=5e-57]; ENSMUSG00000021236, Entpd5, ectonucleoside triphosphate diphosphohydrolase 5, [Score=189, Expect=2e-54]} {Dmel: FBgn0024947, NTPase, [Score=165, Expect=8e-46]} {Celegans: WBGene00010697, uda-1, Nucleoside-diphosphatase uda-1, [Score=144, Expect=6e-38]} {Smed: dd_Smed_v6_8855_0_2, dd_Smed_v6_8855_0_2, [Score=178, Expect=8e-51]} {RNA1509_19635, RNA1509_40383, RNA1509_54757} {RNA1310_14737, RNA1509_19635, RNA1509_40383, RNA1509_54757} {RNA1509_19635, RNA1509_40383, RNA1509_54757, RNA815_6957}

Mlig455_012802 {REF} {Length: 1599} {Pfam: GDA1/CD39 (nucleoside phosphatase) family [PF01150.19, score=124.4]; Ppx/GppA phosphatase family [PF02541.18, score=18.4]} {Human: ENSG00000197586, ENTPD6, ectonucleoside triphosphate diphosphohydrolase 6 (putative), [Score=138, Expect=7e-36]; ENSG00000187097, ENTPD5, ectonucleoside triphosphate diphosphohydrolase 5, [Score=134, Expect=9e-35]} {Mouse: ENSMUSG00000033068, Entpd6, ectonucleoside triphosphate diphosphohydrolase 6, [Score=138, Expect=3e-36]; ENSMUSG00000021236, Entpd5, ectonucleoside triphosphate diphosphohydrolase 5, [Score=132, Expect=3e-34]} {Dmel: FBgn0024947, NTPase, [Score=118, Expect=5e-29]} {Celegans: WBGene00010697, uda-1, Nucleoside-diphosphatase uda-1, [Score=95.1, Expect=4e-21]} {Smed: dd_Smed_v6_8855_0_2, dd_Smed_v6_8855_0_2, [Score=120, Expect=3e-30]} {RNA1509_40383, RNA1509_51501} {RNA1310_14737, RNA1509_51501} {RNA1509_51501, RNA815_6957}
50. MligTC455_33006 2208 45.99 Mlig455_063158

Neo: -

Age: Down-Up-Up

Region-enriched R4: 2.219/0.00001
Region-enriched R3: 1.514/0.00240

1.729 0.768 - - 0.961 - - Mlig455_063158 {REF} {Length: 2059} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=27.0]} {RNA1509_4524} {RNA1310_31808} {RNA815_13487}
51. MligTC455_16462 248 5.17 Mlig455_058597

Neo: -

Age: Down-Down-Up

Region-enriched R4: 2.200/0.02502
Region-enriched R3: 2.087/0.02407
Region-enriched R5: 1.741/0.03183

1.694 0.720 - - 0.974 - - Mlig455_058597 {REF} {Length: 2499} {RNA1509_26769, RNA1509_36389, RNA1509_43355} {RNA1310_44087, RNA1509_26769, RNA1509_36389, RNA1509_43355} {RNA1509_26769, RNA1509_36389, RNA1509_43355, RNA815_22536}
52. MligTC455_36665 2410 50.21 Mlig455_028654

Neo: -

Age: logFC(26M/2M)=0.273

Region-enriched R3: 1.404/0.00674

PSAP 1.694 0.730 - - 0.964 - - Mlig455_028654 {REF} {Length: 3951} {Pfam: Saposin-like type B, region 1 [PF05184.17, score=340.1]; Saposin-like type B, region 2 [PF03489.19, score=316.5]; Homeodomain-like domain [PF13384.8, score=47.9]; Helix-turn-helix domain [PF13518.8, score=39.6]; Saposin A-type domain [PF02199.17, score=35.5]; Protein of unknown function (DUF2753) [PF10952.10, score=31.0]; Replication factor RFC1 C terminal domain [PF08519.14, score=24.2]; Winged helix-turn helix [PF13551.8, score=23.7]; HD domain [PF13023.8, score=21.9]; Delta endotoxin [PF18449.3, score=19.6]} {Human: ENSG00000197746, PSAP, prosaposin, [RH, Score=177, Expect=9e-47]} {Mouse: ENSMUSG00000004207, Psap, prosaposin, [RH, Score=154, Expect=6e-39]} {Dmel: FBgn0000416, Sap-r, Saposin-related, [RH, Score=245, Expect=3e-67]} {Smed: dd_Smed_v6_266_0_1, dd_Smed_v6_266_0_1, [Score=99.0, Expect=1e-22]} {RNA1509_1917} {RNA1310_9056} {RNA815_5033.1}
53. MligTC455_15832 1195 24.9 Mlig455_048167

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.477

Region-enriched R4: 1.763/0.00304
Region-enriched R3: 1.641/0.00124
Region-enriched R5: 1.086/0.02606

1.692 - 0.734 - 0.958 - - Mlig455_048167 {REF} {Length: 3287} {Dmel: FBgn0033252, CG12769, [Score=60.1, Expect=2e-09]} {RNA1509_7124} {RNA1310_24518, RNA1509_7124} {RNA1509_7124, RNA815_12801}
54. MligTC455_27556 557 11.6 Mlig455_020263

Neo: -

Age: Down-Down-Up

Region-enriched R3: 2.024/0.00741

1.69 - - 0.740 0.950 - - Mlig455_020263 {REF} {Length: 2267} {RNA1509_15552} {RNA1310_15792, RNA1509_15552} {RNA1509_15552, RNA815_5911}
55. MligTC455_19214 797 16.61 Mlig455_067480, Mlig455_067488

Neo: -

Age: logFC(26M/2M)=0.411

Region-enriched R4: 2.048/0.00458

HSD11B1 0.98 - - - 0.980 - -

Mlig455_067480 {REF} {Length: 1095} {Pfam: short chain dehydrogenase [PF00106.27, score=63.8]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=42.8]} {Human: ENSG00000117594, HSD11B1, hydroxysteroid 11-beta dehydrogenase 1, [Score=83.6, Expect=1e-18]} {Mouse: ENSMUSG00000029311, Hsd17b11, hydroxysteroid (17-beta) dehydrogenase 11, [Score=59.7, Expect=2e-10]} {Dmel: FBgn0039043, CG17121, [Score=49.7, Expect=7e-07]} {RNA1509_28182} {RNA1310_27439} {RNA815_13316}

Mlig455_067488 {REF} {Length: 1390} {Pfam: short chain dehydrogenase [PF00106.27, score=128.2]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=83.0]; KR domain [PF08659.12, score=25.0]; Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [PF02882.21, score=18.0]} {Human: ENSG00000117594, HSD11B1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=158, Expect=4e-46]} {Mouse: ENSMUSG00000016194, Hsd11b1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=151, Expect=1e-43]} {Dmel: FBgn0051548, CG31548, [Score=80.9, Expect=2e-17]} {Celegans: WBGene00019885, R05D8.7, [Score=80.1, Expect=3e-17]} {Smed: dd_Smed_v6_3167_0_1, dd_Smed_v6_3167_0_1, [Score=71.6, Expect=2e-14]} {RNA1509_28182, RNA1509_29712, RNA1509_41682} {RNA1310_27439, RNA1509_28182, RNA1509_29712, RNA1509_41682} {RNA1509_28182, RNA1509_29712, RNA1509_41682, RNA815_13316}
56. MligTC455_19213 332 6.92 Mlig455_027303

Neo: -

Age: -

Region-enriched R4: 3.653/0.00406
Region-enriched R3: 2.959/0.01217
Region-enriched R5: 2.470/0.02256

HSD11B1 0.977 - - - 0.977 - - Mlig455_027303 {REF} {Length: 1227} {Pfam: short chain dehydrogenase [PF00106.27, score=127.7]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=83.9]; KR domain [PF08659.12, score=25.0]} {Human: ENSG00000117594, HSD11B1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=161, Expect=2e-47]} {Mouse: ENSMUSG00000016194, Hsd11b1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=151, Expect=1e-43]} {Dmel: FBgn0051548, CG31548, [Score=79.7, Expect=4e-17]} {Celegans: WBGene00019885, R05D8.7, [Score=80.1, Expect=3e-17]} {Smed: dd_Smed_v6_4614_0_1, dd_Smed_v6_4614_0_1, [Score=72.4, Expect=1e-14]} {RNA1509_41682} {RNA1310_27439} {RNA815_13316}
57. MligTC455_12343 252 5.25 Mlig455_004664

Neo: Germline

Age: -

Region-enriched R4: 2.851/0.00071

0.973 - - - 0.973 - - Mlig455_004664 {REF} {Length: 1100} {Pfam: AMOP domain [PF03782.19, score=43.4]} {Dmel: FBgn0051004, mesh, [Score=46.6, Expect=1e-05]} {RNA1509_31294} {RNA1310_32024, RNA1509_31294} {RNA1509_31294, RNA815_16383}
58. MligTC455_36228 588 12.25 Mlig455_028918

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=1.158

0.97 - - - 0.970 - - Mlig455_028918 {REF} {Length: 20820} {Pfam: Domain of unknown function (DUF4384) [PF14326.8, score=19.6]} {RNA1509_5854} {RNA1310_268.1} {RNA815_437}
59. MligTC455_52450 1579 32.89 Mlig455_000119

Neo: -

Age: logFC(26M/2M)=0.275

Region-enriched R4: 1.401/0.02633

0.97 - - - 0.970 - - Mlig455_000119 {REF} {Length: 2142} {Pfam: Pacifastin inhibitor (LCMII) [PF05375.15, score=70.3]} {RNA1509_1907, RNA1509_19429, RNA1509_6458} {RNA1310_12956, RNA1509_19429, RNA1509_6458} {RNA1509_19429, RNA1509_6458, RNA815_4763}
60. MligTC455_52451 1458 30.38 Mlig455_000136

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.272

Region-enriched R4: 1.299/0.04830

0.969 - - - 0.969 - - Mlig455_000136 {REF} {Length: 2129} {Pfam: Pacifastin inhibitor (LCMII) [PF05375.15, score=71.0]} {RNA1509_1907, RNA1509_6719} {RNA1310_12956, RNA1509_1907, RNA1509_6719} {RNA1509_1907, RNA1509_6719, RNA815_4763}
61. MligTC455_49841 536 11.17 Mlig455_054891

Neo: -

Age: logFC(26M/2M)=-0.423

Region-enriched R5: 1.350/0.04241

MMEL1 0.968 - - - 0.968 - - Mlig455_054891 {REF} {Length: 2632} {Pfam: Peptidase family M13 [PF05649.15, score=201.7]; Peptidase family M13 [PF01431.23, score=93.2]} {Human: ENSG00000142606, MMEL1, membrane metalloendopeptidase like 1, [Score=182, Expect=2e-47]; ENSG00000277131, MMEL1, membrane metalloendopeptidase like 1, [Score=182, Expect=2e-47]; ENSG00000117298, ECE1, endothelin converting enzyme 1, [Score=181, Expect=4e-47]; ENSG00000171551, ECEL1, endothelin converting enzyme like 1, [Score=177, Expect=9e-46]; ENSG00000145194, ECE2, endothelin converting enzyme 2, [Score=176, Expect=3e-45]; ENSG00000284917, EEF1AKMT4-ECE2, EEF1AKMT4-ECE2 readthrough, [Score=175, Expect=9e-45]} {Mouse: ENSMUSG00000058183, Mmel1, membrane metallo-endopeptidase-like 1, [Score=194, Expect=7e-52]} {Dmel: FBgn0029843, Nep1, Neprilysin 1, [Score=187, Expect=4e-49]} {Celegans: WBGene00017557, nep-11, Neprilysin-11, [Score=158, Expect=8e-40]} {Smed: dd_Smed_v6_1910_0_1, dd_Smed_v6_1910_0_1, [Score=167, Expect=5e-43]} {RNA1509_16049, RNA1509_48689} {RNA1310_4911.1, RNA1509_48689} {RNA1509_48689, RNA815_2994}
62. MligTC455_45384 708 14.76 Mlig455_020701, Mlig455_020769

Neo: -

Age: Down-Down-Up

SUGCT 0.964 - - - 0.964 - -

Mlig455_020701 {REF} {Length: 2068} {Pfam: CoA-transferase family III [PF02515.19, score=362.0]} {Human: ENSG00000175600, SUGCT, succinyl-CoA:glutarate-CoA transferase, [Score=370, Expect=8e-126]} {Mouse: ENSMUSG00000055137, Sugct, succinyl-CoA glutarate-CoA transferase, [Score=366, Expect=3e-124]} {Dmel: FBgn0038804, CG10877, [Score=345, Expect=4e-116]} {Celegans: WBGene00014128, ZK892.4, CaiB/baiF CoA-transferase family protein ZK892.4, [Score=93.2, Expect=5e-21]} {Smed: dd_Smed_v6_9420_0_1, dd_Smed_v6_9420_0_1, [Score=332, Expect=5e-112]} {RNA1509_48074} {RNA1310_24642, RNA1509_48074}

Mlig455_020769 {REF} {Length: 1733} {TRANSSPLICED} {Pfam: CoA-transferase family III [PF02515.19, score=104.7]} {Human: ENSG00000175600, SUGCT, succinyl-CoA:glutarate-CoA transferase, [Score=147, Expect=7e-39]} {Mouse: ENSMUSG00000055137, Sugct, succinyl-CoA glutarate-CoA transferase, [Score=149, Expect=2e-39]} {Dmel: FBgn0038804, CG10877, [Score=148, Expect=5e-39]} {Smed: dd_Smed_v6_9420_0_1, dd_Smed_v6_9420_0_1, [Score=125, Expect=2e-31]} {RNA1509_53402} {RNA1310_49818, RNA1509_53402}
63. MligTC455_36347 2542 52.97 Mlig455_027675

Neo: -

Age: -

ACP7 0.963 - - - 0.963 - - Mlig455_027675 {REF} {Length: 2194} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=89.6]; Iron/zinc purple acid phosphatase-like protein C [PF14008.8, score=79.5]; Purple acid Phosphatase, N-terminal domain [PF16656.7, score=75.2]; PhoD-like phosphatase [PF09423.12, score=19.2]} {Human: ENSG00000183760, ACP7, acid phosphatase 7, tartrate resistant (putative), [RH, Score=431, Expect=2e-148]} {Mouse: ENSMUSG00000037469, Acp7, acid phosphatase 7, tartrate resistant, [RH, Score=448, Expect=1e-154]} {Dmel: FBgn0030245, CG1637, [RH, Score=434, Expect=9e-150]} {Celegans: WBGene00219316, F21A3.11, Purple acid phosphatase, [RH, Score=406, Expect=2e-138]} {Smed: dd_Smed_v6_1053_0_1, dd_Smed_v6_1053_0_1, [RH, Score=537, Expect=0.0]} {RNA1509_2158} {RNA1310_12511.1, RNA1509_2158} {RNA1509_2158, RNA815_6230.1}
64. MligTC455_35665 550 11.46 Mlig455_000411

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.492

AC099489.1 0.961 - - - 0.961 - - Mlig455_000411 {REF} {Length: 12958} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=89.4]; Domain of unknown function (DUF1943) [PF09172.13, score=66.3]; von Willebrand factor type D domain [PF00094.27, score=25.5]} {Human: ENSG00000188897, AC099489.1, vitellogenin, [Score=122, Expect=1e-26]} {Dmel: FBgn0032136, Apoltp, Apolipoprotein lipid transfer particle, [Score=74.3, Expect=3e-12]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=93.6, Expect=3e-18]} {RNA1509_862} {RNA1310_65.2} {RNA815_55}
65. MligTC455_14550 82 1.72 Mlig455_016928

Neo: -

Age: Down-Up-Up

Region-enriched R4: 4.810/0.01442

GRASP 0.96 - - - 0.960 - - Mlig455_016928 {REF} {Length: 1233} {Pfam: PDZ domain [PF17820.3, score=33.1]; PDZ domain [PF00595.26, score=25.0]} {Human: ENSG00000161835, GRASP, general receptor for phosphoinositides 1 associated scaffold protein, [RH, Score=55.8, Expect=5e-09]} {Mouse: ENSMUSG00000000531, Grasp, GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein, [RH, Score=58.5, Expect=5e-10]} {Dmel: FBgn0035676, ssp6, short spindle 6, [RH, Score=87.8, Expect=3e-20]} {Celegans: WBGene00009272, gras-1, GRASP (General Receptor for phosphoinositides 1-Associated Scaffold Protein) homolog, [RH, Score=64.7, Expect=9e-13]} {RNA1509_57284} {RNA1310_36717} {RNA815_20577}
66. MligTC455_19299 65 1.35 Mlig455_001048

Neo: -

Age: -

0.958 - - - 0.958 - - Mlig455_001048 {REF} {Length: 2071} {NoTransDecoderORF} {RNA1310_76604}
67. MligTC455_43406 1382 28.79 Mlig455_063546

Neo: -

Age: logFC(26M/2M)=-0.363

Region-enriched R4: 1.356/0.01589
Region-enriched R3: 1.139/0.04629

TRPA1 0.957 - - - 0.957 - - Mlig455_063546 {REF} {Length: 5889} {Pfam: Ion transport protein [PF00520.33, score=52.1]; Ankyrin repeat [PF00023.32, score=19.5]} {Human: ENSG00000104321, TRPA1, transient receptor potential cation channel subfamily A member 1, [Score=130, Expect=7e-30]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=127, Expect=5e-29]} {Dmel: FBgn0035934, TrpA1, Transient receptor potential cation channel A1, [Score=139, Expect=6e-33]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=153, Expect=2e-37]} {Smed: dd_Smed_v6_6201_0_2, dd_Smed_v6_6201_0_2, [Score=132, Expect=7e-31]} {RNA1509_21433, RNA1509_40381, RNA1509_43070, RNA1509_46763} {RNA1310_1768.1, RNA1509_21433, RNA1509_40381, RNA1509_43070} {RNA1509_21433, RNA1509_40381, RNA1509_43070, RNA815_3153}
68. MligTC455_43800 4639 96.64 Mlig455_041018, Mlig455_041127, Mlig455_041183

Neo: -

Age: -

RGN 0.954 - - - 0.954 - -

Mlig455_041018 {REF} {Length: 1500} {TRANSSPLICED} {Pfam: SMP-30/Gluconolactonase/LRE-like region [PF08450.14, score=221.4]; Two component regulator propeller [PF07494.13, score=22.9]} {Human: ENSG00000130988, RGN, regucalcin, [RH, Score=187, Expect=4e-57]} {Mouse: ENSMUSG00000023070, Rgn, regucalcin, [RH, Score=190, Expect=3e-58]} {Dmel: FBgn0030362, regucalcin, [Score=142, Expect=6e-40]} {Smed: dd_Smed_v6_3808_0_1, dd_Smed_v6_3808_0_1, [RH, Score=176, Expect=5e-53]} {RNA1509_3252} {RNA1310_20018.1} {RNA815_8819.1}

Mlig455_041127 {REF} {Length: 1500} {TRANSSPLICED} {Pfam: SMP-30/Gluconolactonase/LRE-like region [PF08450.14, score=216.7]; Two component regulator propeller [PF07494.13, score=22.9]} {Human: ENSG00000130988, RGN, regucalcin, [RH, Score=181, Expect=1e-54]} {Mouse: ENSMUSG00000023070, Rgn, regucalcin, [RH, Score=184, Expect=3e-56]} {Dmel: FBgn0038257, smp-30, Senescence marker protein-30, [Score=145, Expect=3e-41]} {Smed: dd_Smed_v6_3808_0_1, dd_Smed_v6_3808_0_1, [RH, Score=178, Expect=8e-54]} {RNA1509_3252} {RNA1310_7497.1} {RNA815_8819.1}

Mlig455_041183 {REF} {Length: 1502} {TRANSSPLICED} {Pfam: SMP-30/Gluconolactonase/LRE-like region [PF08450.14, score=216.7]; Two component regulator propeller [PF07494.13, score=22.9]} {Human: ENSG00000130988, RGN, regucalcin, [RH, Score=182, Expect=5e-55]} {Mouse: ENSMUSG00000023070, Rgn, regucalcin, [RH, Score=186, Expect=9e-57]} {Dmel: FBgn0038257, smp-30, Senescence marker protein-30, [Score=145, Expect=4e-41]} {Smed: dd_Smed_v6_3808_0_1, dd_Smed_v6_3808_0_1, [RH, Score=176, Expect=3e-53]} {RNA1509_3252} {RNA1310_7497.1} {RNA815_8819.1}
69. MligTC455_26718 49 1.02 Mlig455_002028

Neo: -

Age: -

CHRNA7 0.953 - - - 0.953 - - Mlig455_002028 {REF} {Length: 5293} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=163.3]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=127.1]; C2H2-type zinc finger [PF13894.8, score=21.7]} {Human: ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=236, Expect=6e-67]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=236, Expect=6e-67]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=234, Expect=3e-66]; ENSG00000174343, CHRNA9, cholinergic receptor nicotinic alpha 9 subunit, [Score=231, Expect=1e-65]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=235, Expect=1e-66]; ENSMUSG00000029205, Chrna9, cholinergic receptor, nicotinic, alpha polypeptide 9, [Score=234, Expect=2e-66]} {Dmel: FBgn0028875, nAChRalpha5, nicotinic Acetylcholine Receptor alpha5, [Score=253, Expect=3e-70]} {Celegans: WBGene00000060, acr-21, AcetylCholine Receptor, [Score=234, Expect=6e-67]} {Smed: dd_Smed_v6_23922_0_1, dd_Smed_v6_23922_0_1, [Score=240, Expect=4e-68]} {RNA1509_23865} {RNA1310_13309} {RNA815_11085}
70. MligTC455_20135 1861 38.76 Mlig455_051349

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.876

Region-enriched R4: 2.367/0.00063
Region-enriched R5: 1.267/0.03902

ATP1B2 0.952 - - - 0.952 - - Mlig455_051349 {REF} {Length: 1394} {Pfam: Sodium / potassium ATPase beta chain [PF00287.20, score=191.3]} {Human: ENSG00000129244, ATP1B2, ATPase Na+/K+ transporting subunit beta 2, [Score=102, Expect=2e-24]} {Mouse: ENSMUSG00000041329, Atp1b2, ATPase, Na+/K+ transporting, beta 2 polypeptide, [Score=102, Expect=2e-24]} {Dmel: FBgn0015777, nrv2, nervana 2, [Score=145, Expect=2e-40]} {Celegans: WBGene00007646, nkb-1, Sodium/potassium-transporting ATPase subunit beta-1, [Score=151, Expect=7e-43]} {Smed: dd_Smed_v6_2230_0_4, dd_Smed_v6_2230_0_4, [RH, Score=211, Expect=2e-66]} {RNA1509_2976} {RNA1310_26809} {RNA815_11848}
71. MligTC455_22311 74 1.53 Mlig455_001822

Neo: -

Age: -

0.952 - - - 0.952 - - Mlig455_001822 {REF} {Length: 1911} {RNA1310_30832} {RNA815_15518}
72. MligTC455_27044 212 4.41 Mlig455_032586

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.476

Region-enriched R1: 6.548/0.04974
Region-enriched R4: 4.510/0.00055

0.95 - - - 0.950 - - Mlig455_032586 {REF} {Length: 5055} {Pfam: Fibronectin type III domain [PF00041.23, score=40.4]} {RNA1509_39470} {RNA1310_213.1} {RNA815_43.1}

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