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Results for MligTC455_37239

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_37239 1846 38.46 Mlig455_060082

Neo: -

Age: -

Region-enriched R3: 1.562/0.04763
Region-enriched R5: 1.292/0.04648

PANK4 Mlig455_060082 {REF} {Length: 1532} {Pfam: Fumble [PF03630.16, score=120.5]} {Human: ENSG00000273494, PANK4, pantothenate kinase 4, [Score=106, Expect=2e-24]; ENSG00000157881, PANK4, pantothenate kinase 4, [Score=106, Expect=2e-24]} {Mouse: ENSMUSG00000029056, Pank4, pantothenate kinase 4, [Score=97.4, Expect=1e-21]} {Dmel: FBgn0011205, fbl, fumble, [Score=66.2, Expect=7e-12]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [Score=170, Expect=1e-49]} {RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233} {RNA1310_20224, RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233} {RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233, RNA815_7673}

Cumulative graph for MligTC455_37239

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.471 5.572 0.62383 1.00000
RegionR2 -1.956 5.572 0.00770 0.08538
RegionR3 1.562 5.572 0.00190 0.04763
RegionR4 1.315 5.572 0.02908 0.13297
RegionR5 1.292 5.572 0.00742 0.04648
RegionR6 1.087 5.572 0.04110 0.38076
RegionR7 -2.361 5.572 0.00229 0.06288
RegionR8 -1.41 5.572 0.10175 0.59740

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.647 5.572 0.60081 1.00000
RegenerationR2 -0.185 5.572 0.79960 0.98992
RegenerationR3 -1.094 5.572 0.10684 0.51680
RegenerationR4 -0.952 5.572 0.18719 0.62973
RegenerationR5 -1.144 5.572 0.09388 0.46967
RegenerationR6 -0.611 5.572 0.36081 0.70503
RegenerationBL 0.044 5.572 0.94872 1.00000
RegenerationTP -1.282 5.572 0.17483 0.60849


Genes with expression patterns similar to MligTC455_37239

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_37239 1846 38.46 Mlig455_060082

Neo: -

Age: -

Region-enriched R3: 1.562/0.04763
Region-enriched R5: 1.292/0.04648

PANK4 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_060082 {REF} {Length: 1532} {Pfam: Fumble [PF03630.16, score=120.5]} {Human: ENSG00000273494, PANK4, pantothenate kinase 4, [Score=106, Expect=2e-24]; ENSG00000157881, PANK4, pantothenate kinase 4, [Score=106, Expect=2e-24]} {Mouse: ENSMUSG00000029056, Pank4, pantothenate kinase 4, [Score=97.4, Expect=1e-21]} {Dmel: FBgn0011205, fbl, fumble, [Score=66.2, Expect=7e-12]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [Score=170, Expect=1e-49]} {RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233} {RNA1310_20224, RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233} {RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233, RNA815_7673}
2. MligTC455_18723 1597 33.27 Mlig455_004384

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.781

Region-enriched R3: 2.164/0.00079
Region-enriched R4: 1.576/0.04930
Region-enriched R5: 1.329/0.03977

SLC3A1 5.324 0.858 0.833 0.867 0.982 0.813 0.971 Mlig455_004384 {REF} {Length: 2040} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=310.6]} {Human: ENSG00000138079, SLC3A1, solute carrier family 3 member 1, [RH, Score=371, Expect=2e-119]} {Mouse: ENSMUSG00000024131, Slc3a1, solute carrier family 3, member 1, [RH, Score=372, Expect=4e-120]} {Dmel: FBgn0002570, Mal-A1, Maltase A1, [RH, Score=384, Expect=2e-126]} {Celegans: WBGene00000224, atgp-1, Amino acid Transporter GlycoProtein subunit, [RH, Score=146, Expect=3e-37]} {Smed: dd_Smed_v6_2113_0_1, dd_Smed_v6_2113_0_1, [Score=67.8, Expect=8e-12]} {RNA1509_19345} {RNA1310_12682.1} {RNA815_15968}
3. MligTC455_18724 1612 33.59 Mlig455_037198

Neo: -

Age: -

Region-enriched R3: 2.022/0.00141

SLC3A1 5.317 0.855 0.838 0.867 0.982 0.803 0.972 Mlig455_037198 {REF} {Length: 2052} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=311.9]} {Human: ENSG00000138079, SLC3A1, solute carrier family 3 member 1, [RH, Score=373, Expect=2e-120]} {Mouse: ENSMUSG00000024131, Slc3a1, solute carrier family 3, member 1, [RH, Score=374, Expect=5e-121]} {Dmel: FBgn0002570, Mal-A1, Maltase A1, [RH, Score=385, Expect=1e-126]} {Celegans: WBGene00000225, atgp-2, Amino acid Transporter GlycoProtein subunit, [RH, Score=147, Expect=2e-37]} {Smed: dd_Smed_v6_2113_0_1, dd_Smed_v6_2113_0_1, [Score=67.8, Expect=9e-12]} {RNA1509_14094, RNA1509_15182, RNA1509_19345} {RNA1310_12682.1, RNA1509_14094, RNA1509_15182, RNA1509_19345} {RNA1509_14094, RNA1509_15182, RNA1509_19345, RNA815_15968}
4. MligTC455_14822 1135 23.64 Mlig455_018937, Mlig455_018944

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.579

Region-enriched R4: 1.878/0.00075
Region-enriched R3: 1.574/0.00063
Region-enriched R5: 1.391/0.00033

Regeneration-downregulated R3: -1.760

Regeneration-depleted R3: -1.760

PANK1 5.238 0.822 0.903 0.948 0.952 0.720 0.893

Mlig455_018937 {REF} {Length: 2205} {Pfam: Fumble [PF03630.16, score=44.5]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [Score=64.7, Expect=3e-12]} {RNA1509_12016} {RNA1310_16423} {RNA815_7574.1}

Mlig455_018944 {REF} {Length: 2211} {Pfam: Fumble [PF03630.16, score=101.1]} {Human: ENSG00000152782, PANK1, pantothenate kinase 1, [Score=55.5, Expect=6e-08]} {Mouse: ENSMUSG00000029056, Pank4, pantothenate kinase 4, [Score=80.1, Expect=8e-16]} {Dmel: FBgn0011205, fbl, fumble, [Score=56.2, Expect=2e-08]} {Celegans: WBGene00004068, pnk-1, PaNtothenate Kinase, [Score=75.1, Expect=1e-14]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [Score=181, Expect=7e-54]} {RNA1509_12016} {RNA1310_16423, RNA1509_12016} {RNA1509_12016, RNA815_7574.1}
5. MligTC455_43756 3225 67.19 Mlig455_010402

Neo: -

Age: -

Region-enriched R3: 1.722/0.00762

5.192 0.787 0.732 0.839 0.957 0.938 0.939 Mlig455_010402 {REF} {Length: 2001} {Pfam: Innexin [PF00876.20, score=339.7]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=100, Expect=3e-23]} {Celegans: WBGene00006749, unc-9, Innexin unc-9, [Score=291, Expect=2e-95]} {Smed: dd_Smed_v6_734_0_2, dd_Smed_v6_734_0_2, [Score=292, Expect=3e-95]} {RNA1509_21594, RNA1509_22136, RNA1509_30214, RNA1509_32964, RNA1509_3943, RNA1509_49855} {RNA1310_16777, RNA1509_21594, RNA1509_22136, RNA1509_30214, RNA1509_32964, RNA1509_3943, RNA1509_49855} {RNA1509_21594, RNA1509_22136, RNA1509_30214, RNA1509_32964, RNA1509_3943, RNA1509_49855, RNA815_7295}
6. MligTC455_53810 10368 216.01 Mlig455_015254

Neo: -

Age: logFC(26M/2M)=-0.519

Region-enriched R3: 1.584/0.00569
Region-enriched R5: 1.232/0.02515

SULT1C4 5.154 0.908 0.891 0.730 0.978 0.818 0.829 Mlig455_015254 {REF} {Length: 3712} {Pfam: Sulfotransferase domain [PF00685.29, score=172.2]; Sulfotransferase family [PF13469.8, score=31.5]} {Human: ENSG00000198075, SULT1C4, sulfotransferase family 1C member 4, [Score=168, Expect=6e-50]; ENSG00000198203, SULT1C2, sulfotransferase family 1C member 2, [Score=167, Expect=7e-50]} {Mouse: ENSMUSG00000023122, Sult1c2, sulfotransferase family, cytosolic, 1C, member 2, [Score=163, Expect=3e-48]} {Dmel: FBgn0034887, St1, Sulfotransferase 1, [Score=111, Expect=2e-28]} {Celegans: WBGene00013748, ssu-1, Suppressor of Stomatin mutant Uncoordination, [Score=99.0, Expect=2e-23]} {Smed: dd_Smed_v6_4622_0_1, dd_Smed_v6_4622_0_1, [Score=152, Expect=1e-44]} {RNA1509_178, RNA1509_182} {RNA1310_14124, RNA1509_178, RNA1509_182} {RNA1509_178, RNA1509_182, RNA815_6793}
7. MligTC455_42352 5331 111.06 Mlig455_014325

Neo: -

Age: -

Region-enriched R3: 1.607/0.00131
Region-enriched R5: 1.102/0.02723

ACE 5.093 0.799 0.792 0.884 0.954 0.730 0.934 Mlig455_014325 {REF} {Length: 2705} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=705.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0016122, Acer, Angiotensin-converting enzyme-related, [RH, Score=426, Expect=4e-141]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=191, Expect=3e-51]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=411, Expect=1e-135]} {RNA1509_441, RNA1509_9027} {RNA1310_8949, RNA1509_441, RNA1509_9027} {RNA1509_441, RNA1509_9027, RNA815_4061}
8. MligTC455_24859 5590 116.45 Mlig455_054066, Mlig455_063284

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.306

Region-enriched R3: 2.202/0.00434

5.086 0.863 0.837 0.791 0.761 0.879 0.955

Mlig455_054066 {REF} {Length: 1406} {RNA1509_33411, RNA1509_7753} {RNA1310_22791, RNA1509_33411} {RNA1509_33411, RNA815_10514.1}

Mlig455_063284 {REF} {Length: 1414} {Pfam: Multi-glycosylated core protein 24 (MGC-24), sialomucin [PF05283.13, score=46.5]} {Mouse: ENSMUSG00000050912, Tmem123, transmembrane protein 123, [Score=46.6, Expect=2e-06]} {Dmel: FBgn0045823, vsg, visgun, [Score=53.1, Expect=8e-09]} {Smed: dd_Smed_v6_828_0_1, dd_Smed_v6_828_0_1, [RH, Score=53.5, Expect=2e-10]} {RNA1509_7753} {RNA1310_22791} {RNA815_10514.1}
9. MligTC455_42353 5099 106.23 Mlig455_014274, Mlig455_014309, Mlig455_018673

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.786

Region-enriched R3: 2.226/0.00003

AC113554.1, ACE 5.065 0.760 0.769 0.820 0.977 0.763 0.976

Mlig455_014274 {REF} {Length: 2949} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=705.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0016122, Acer, Angiotensin-converting enzyme-related, [RH, Score=426, Expect=4e-141]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=191, Expect=3e-51]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=411, Expect=1e-135]} {RNA1509_37062, RNA1509_441} {RNA1310_8949, RNA1509_37062} {RNA1509_37062, RNA815_4061}

Mlig455_014309 {REF} {Length: 2926} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=705.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0016122, Acer, Angiotensin-converting enzyme-related, [RH, Score=426, Expect=4e-141]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=191, Expect=3e-51]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=411, Expect=1e-135]} {RNA1509_441} {RNA1310_8949} {RNA815_4061}

Mlig455_018673 {REF} {Length: 833} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=122.4]} {Human: ENSG00000264813, AC113554.1, novel transcript, [Score=103, Expect=3e-24]; ENSG00000159640, ACE, angiotensin I converting enzyme, [Score=103, Expect=2e-24]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [Score=97.8, Expect=2e-22]; ENSMUSG00000101605, Ace3, angiotensin I converting enzyme (peptidyl-dipeptidase A) 3, [Score=93.2, Expect=6e-21]} {Dmel: FBgn0012037, Ance, Angiotensin converting enzyme, [Score=74.7, Expect=7e-15]} {Smed: dd_Smed_v6_13804_0_1, dd_Smed_v6_13804_0_1, [Score=51.2, Expect=2e-07]} {RNA1509_16360} {RNA1310_8949} {RNA815_4061}
10. MligTC455_41503 3372 70.25 Mlig455_015421

Neo: -

Age: -

Region-enriched R3: 1.663/0.00123

5.045 0.796 0.754 0.869 0.956 0.721 0.949 Mlig455_015421 {REF} {Length: 3377} {Pfam: Fasciclin domain [PF02469.24, score=41.0]} {Dmel: FBgn0032638, SPH93, Serine protease homolog 93, [Score=61.6, Expect=2e-09]} {RNA1509_26815, RNA1509_27548, RNA1509_56488} {RNA1310_8987, RNA1509_26815, RNA1509_27548, RNA1509_56488} {RNA1509_26815, RNA1509_27548, RNA1509_56488, RNA815_3084.1}
11. MligTC455_45572 697 14.53 Mlig455_014345

Neo: -

Age: -

Region-enriched R4: 2.663/0.00001
Region-enriched R3: 1.769/0.00087
Region-enriched R5: 1.541/0.00135
Region-enriched R6: 1.390/0.04169

CRYL1 4.96 0.832 0.817 0.738 0.952 0.723 0.898 Mlig455_014345 {REF} {Length: 1372} {Pfam: 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain [PF02737.20, score=152.8]; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain [PF00725.24, score=40.7]} {Human: ENSG00000165475, CRYL1, crystallin lambda 1, [RH, Score=275, Expect=6e-91]} {Mouse: ENSMUSG00000021947, Cryl1, crystallin, lambda 1, [RH, Score=261, Expect=7e-86]} {Dmel: FBgn0030737, CG9914, [RH, Score=287, Expect=4e-96]} {Celegans: WBGene00022130, Y71F9B.9, [RH, Score=249, Expect=2e-81]} {Smed: dd_Smed_v6_1696_0_1, dd_Smed_v6_1696_0_1, [RH, Score=176, Expect=6e-53]} {RNA1509_34725} {RNA1310_23652} {RNA815_8421.1}
12. MligTC455_48070 1559 32.49 Mlig455_019661

Neo: -

Age: logFC(26M/2M)=-0.328

Region-enriched R3: 1.615/0.01457

HSD11B1 4.92 0.833 0.747 0.718 0.962 0.704 0.956 Mlig455_019661 {REF} {Length: 1828} {Pfam: short chain dehydrogenase [PF00106.27, score=125.5]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=75.3]; KR domain [PF08659.12, score=27.1]} {Human: ENSG00000117594, HSD11B1, hydroxysteroid 11-beta dehydrogenase 1, [Score=157, Expect=2e-45]} {Mouse: ENSMUSG00000016194, Hsd11b1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=154, Expect=1e-44]} {Dmel: FBgn0027583, CG7601, [Score=82.0, Expect=1e-17]} {Celegans: WBGene00014093, ZK829.1, [Score=74.3, Expect=4e-15]} {Smed: dd_Smed_v6_3167_0_1, dd_Smed_v6_3167_0_1, [Score=62.8, Expect=2e-11]} {RNA1509_11335, RNA1509_15148} {RNA1310_26648, RNA1509_11335, RNA1509_15148} {RNA1509_11335, RNA1509_15148, RNA815_11342}
13. MligTC455_35633 4966 103.45 Mlig455_048471

Neo: -

Age: -

Region-enriched R4: 1.579/0.00682
Region-enriched R3: 1.493/0.00762

DHDH 4.494 0.829 0.857 - 0.958 0.883 0.967 Mlig455_048471 {REF} {Length: 1491} {Pfam: Oxidoreductase family, NAD-binding Rossmann fold [PF01408.24, score=87.6]; Oxidoreductase family, C-terminal alpha/beta domain [PF02894.19, score=32.8]; Homoserine dehydrogenase, NAD binding domain [PF03447.18, score=19.9]} {Human: ENSG00000104808, DHDH, dihydrodiol dehydrogenase, [RH, Score=246, Expect=3e-79]} {Mouse: ENSMUSG00000011382, Dhdh, dihydrodiol dehydrogenase (dimeric), [RH, Score=248, Expect=4e-80]} {Dmel: FBgn0031418, CG3609, [RH, Score=231, Expect=1e-73]} {Smed: dd_Smed_v6_7643_0_1, dd_Smed_v6_7643_0_1, [RH, Score=213, Expect=9e-67]} {RNA1509_1049, RNA1509_4889, RNA1509_8979} {RNA1310_24236, RNA1509_1049, RNA1509_4889, RNA1509_8979} {RNA1509_1049, RNA1509_4889, RNA1509_8979, RNA815_11111.1}
14. MligTC455_48071 1712 35.67 Mlig455_048082

Neo: -

Age: logFC(26M/2M)=-0.321

Region-enriched R4: 1.489/0.04451

HSD11B1 4.489 0.912 0.885 0.777 0.956 - 0.959 Mlig455_048082 {REF} {Length: 1293} {Pfam: short chain dehydrogenase [PF00106.27, score=123.3]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=75.2]; KR domain [PF08659.12, score=26.1]} {Human: ENSG00000117594, HSD11B1, hydroxysteroid 11-beta dehydrogenase 1, [Score=155, Expect=4e-45]} {Mouse: ENSMUSG00000016194, Hsd11b1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=150, Expect=1e-43]} {Dmel: FBgn0027583, CG7601, [Score=82.4, Expect=9e-18]} {Celegans: WBGene00000982, dhs-19, DeHydrogenases, Short chain, [Score=73.2, Expect=1e-14]} {Smed: dd_Smed_v6_4976_0_1, dd_Smed_v6_4976_0_1, [Score=62.8, Expect=3e-11]} {RNA1509_14549, RNA1509_28912} {RNA1310_26648, RNA1509_14549, RNA1509_28912} {RNA1509_14549, RNA1509_28912, RNA815_11342}
15. MligTC455_38362 1015 21.16 Mlig455_045508

Neo: -

Age: -

Region-enriched R4: 1.693/0.01745
Region-enriched R5: 1.163/0.02906

AADAC 4.449 0.813 - 0.877 0.976 0.851 0.932 Mlig455_045508 {REF} {Length: 2224} {Pfam: alpha/beta hydrolase fold [PF07859.15, score=113.1]; Carboxylesterase family [PF00135.30, score=19.9]} {Human: ENSG00000114771, AADAC, arylacetamide deacetylase, [Score=96.3, Expect=2e-21]; ENSG00000197953, AADACL2, arylacetamide deacetylase like 2, [Score=93.6, Expect=2e-20]; ENSG00000261846, AADACL2, arylacetamide deacetylase like 2, [Score=93.6, Expect=2e-20]} {Mouse: ENSMUSG00000090527, Gm5538, predicted gene 5538, [Score=102, Expect=1e-23]; ENSMUSG00000095522, Gm8298, predicted gene 8298, [Score=98.2, Expect=3e-22]} {Dmel: FBgn0034491, Hsl, Hormone-sensitive lipase, [Score=65.5, Expect=4e-11]} {Celegans: WBGene00012810, nceh-1, Neutral Cholesterol Ester Hydrolase homolog, [Score=98.2, Expect=2e-22]} {Smed: dd_Smed_v6_4674_0_1, dd_Smed_v6_4674_0_1, [Score=82.0, Expect=5e-17]} {RNA1509_14307} {RNA1310_15560.2} {RNA815_8354}
16. MligTC455_37113 9210 191.88 Mlig455_020693

Neo: -

Age: -

Region-enriched R3: 1.525/0.00009

LGMN 4.446 0.807 0.803 0.956 0.950 - 0.930 Mlig455_020693 {REF} {Length: 3890} {Pfam: Peptidase C13 family [PF01650.20, score=361.0]} {Human: ENSG00000100600, LGMN, legumain, [RH, Score=382, Expect=2e-129]} {Mouse: ENSMUSG00000021190, Lgmn, legumain, [RH, Score=388, Expect=4e-132]} {Dmel: FBgn0023545, PIG-K, Phosphatidylinositol glycan anchor biosynthesis class K, [Score=127, Expect=1e-32]} {Celegans: WBGene00012144, T28H10.3, [RH, Score=327, Expect=7e-108]} {Smed: dd_Smed_v6_6456_0_1, dd_Smed_v6_6456_0_1, [Score=105, Expect=3e-25]} {RNA1509_312} {RNA1310_13933, RNA1509_312} {RNA1509_312, RNA815_6243.1}
17. MligTC455_18651 2559 53.32 Mlig455_067661

Neo: -

Age: -

Region-enriched R3: 1.583/0.04334

4.436 0.847 0.910 - 0.909 0.788 0.982 Mlig455_067661 {REF} {Length: 616} {RNA1509_2812} {RNA1310_3353.1, RNA1509_2812} {RNA1509_2812, RNA815_7653}
18. MligTC455_38613 969 20.2 Mlig455_048005, Mlig455_063705

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.394

Region-enriched R3: 1.570/0.01256

POSTN 4.421 - 0.824 0.917 0.975 0.738 0.967

Mlig455_048005 {REF} {Length: 629} {Pfam: Fasciclin domain [PF02469.24, score=22.3]} {Smed: dd_Smed_v6_1088_0_1, dd_Smed_v6_1088_0_1, [Score=52.0, Expect=7e-08]} {RNA1509_6801} {RNA1310_9258} {RNA815_5083}

Mlig455_063705 {REF} {Length: 2741} {Pfam: Fasciclin domain [PF02469.24, score=65.6]} {Human: ENSG00000133110, POSTN, periostin, [Score=67.0, Expect=9e-11]} {Mouse: ENSMUSG00000027750, Postn, periostin, osteoblast specific factor, [Score=63.5, Expect=7e-10]} {Smed: dd_Smed_v6_1088_0_1, dd_Smed_v6_1088_0_1, [Score=141, Expect=9e-35]} {RNA1509_45570, RNA1509_6801} {RNA1310_9258, RNA1509_45570, RNA1509_6801} {RNA1509_45570, RNA1509_6801, RNA815_5083}
19. MligTC455_40312 3856 80.34 Mlig455_008661, Mlig455_008672

Neo: -

Age: Down-Up-Up

Region-enriched R3: 2.080/0.00320

CYP2J2 4.42 0.848 0.892 - 0.911 0.811 0.958

Mlig455_008661 {REF} {Length: 2369} {Pfam: Cytochrome P450 [PF00067.24, score=340.8]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [RH, Score=298, Expect=3e-95]} {Mouse: ENSMUSG00000042248, Cyp2c37, cytochrome P450, family 2. subfamily c, polypeptide 37, [RH, Score=280, Expect=2e-88]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=276, Expect=1e-86]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=275, Expect=3e-86]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=274, Expect=6e-86]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [RH, Score=272, Expect=4e-85]; ENSMUSG00000054827, Cyp2c50, cytochrome P450, family 2, subfamily c, polypeptide 50, [RH, Score=270, Expect=2e-84]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=270, Expect=2e-84]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=269, Expect=6e-84]; ENSMUSG00000032808, Cyp2c38, cytochrome P450, family 2, subfamily c, polypeptide 38, [RH, Score=267, Expect=2e-83]; ENSMUSG00000025003, Cyp2c39, cytochrome P450, family 2, subfamily c, polypeptide 39, [RH, Score=266, Expect=5e-83]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=219, Expect=9e-65]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_4449_0_1, dd_Smed_v6_4449_0_1, [Score=262, Expect=1e-81]} {RNA1509_32472, RNA1509_3430} {RNA1310_10280, RNA1509_32472, RNA1509_3430} {RNA1509_32472, RNA1509_3430, RNA815_4805}

Mlig455_008672 {REF} {Length: 2348} {Pfam: Cytochrome P450 [PF00067.24, score=341.0]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [RH, Score=298, Expect=3e-95]} {Mouse: ENSMUSG00000042248, Cyp2c37, cytochrome P450, family 2. subfamily c, polypeptide 37, [RH, Score=280, Expect=2e-88]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=276, Expect=1e-86]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=275, Expect=2e-86]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=274, Expect=5e-86]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [RH, Score=272, Expect=4e-85]; ENSMUSG00000054827, Cyp2c50, cytochrome P450, family 2, subfamily c, polypeptide 50, [RH, Score=270, Expect=2e-84]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=269, Expect=6e-84]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=269, Expect=7e-84]; ENSMUSG00000032808, Cyp2c38, cytochrome P450, family 2, subfamily c, polypeptide 38, [RH, Score=267, Expect=3e-83]; ENSMUSG00000025003, Cyp2c39, cytochrome P450, family 2, subfamily c, polypeptide 39, [RH, Score=266, Expect=6e-83]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=219, Expect=7e-65]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [RH, Score=248, Expect=3e-76]} {Smed: dd_Smed_v6_4449_0_1, dd_Smed_v6_4449_0_1, [Score=261, Expect=3e-81]} {RNA1509_32472} {RNA1310_10280} {RNA815_4805}
20. MligTC455_52436 4103 85.47 Mlig455_036594, Mlig455_057758

Neo: -

Age: -

Region-enriched R3: 2.299/0.00029

FMO4 4.404 0.792 0.881 - 0.924 0.836 0.971

Mlig455_036594 {REF} {Length: 1772} {TRANSSPLICED} {Pfam: Flavin-binding monooxygenase-like [PF00743.21, score=121.5]; Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=43.8]; L-lysine 6-monooxygenase (NADPH-requiring) [PF13434.8, score=21.1]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=18.3]} {Human: ENSG00000076258, FMO4, flavin containing monooxygenase 4, [Score=104, Expect=1e-23]} {Mouse: ENSMUSG00000026560, Fmo9, flavin containing monooxygenase 9, [Score=102, Expect=5e-23]; ENSMUSG00000028088, Fmo5, flavin containing monooxygenase 5, [Score=102, Expect=3e-23]} {Dmel: FBgn0033079, Fmo-2, Flavin-containing monooxygenase 2, [Score=132, Expect=3e-34]} {Celegans: WBGene00016728, C46H11.2, Flavin-containing monooxygenase, [Score=108, Expect=1e-25]} {Smed: dd_Smed_v6_9449_0_1, dd_Smed_v6_9449_0_1, [Score=93.2, Expect=1e-20]} {RNA1509_13926} {RNA1310_13123.1} {RNA815_5157.1}

Mlig455_057758 {REF} {Length: 1759} {TRANSSPLICED} {Pfam: Flavin-binding monooxygenase-like [PF00743.21, score=125.0]; Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=49.5]; FAD-NAD(P)-binding [PF13454.8, score=29.2]; L-lysine 6-monooxygenase (NADPH-requiring) [PF13434.8, score=28.7]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=27.1]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=19.0]; FAD dependent oxidoreductase [PF01266.26, score=18.3]} {Human: ENSG00000076258, FMO4, flavin containing monooxygenase 4, [Score=111, Expect=1e-25]} {Mouse: ENSMUSG00000028088, Fmo5, flavin containing monooxygenase 5, [Score=113, Expect=2e-26]; ENSMUSG00000026560, Fmo9, flavin containing monooxygenase 9, [Score=108, Expect=6e-25]} {Dmel: FBgn0033079, Fmo-2, Flavin-containing monooxygenase 2, [Score=148, Expect=1e-39]} {Celegans: WBGene00016728, C46H11.2, Flavin-containing monooxygenase, [Score=108, Expect=9e-26]} {Smed: dd_Smed_v6_9449_0_1, dd_Smed_v6_9449_0_1, [Score=106, Expect=6e-25]} {RNA1509_13926} {RNA1310_13123.1} {RNA815_5157.1}
21. MligTC455_42341 2131 44.4 Mlig455_015675, Mlig455_062486

Neo: -

Age: logFC(26M/2M)=-0.307

Region-enriched R3: 2.018/0.00002

CYB561A3 4.402 0.880 0.842 0.767 0.974 - 0.939

Mlig455_015675 {REF} {Length: 1331} {Pfam: Eukaryotic cytochrome b561 [PF03188.18, score=116.0]} {Human: ENSG00000162144, CYB561A3, cytochrome b561 family member A3, [Score=123, Expect=1e-33]} {Mouse: ENSMUSG00000034445, Cyb561a3, cytochrome b561 family, member A3, [Score=126, Expect=4e-35]} {Dmel: FBgn0035321, CG1275, [Score=86.3, Expect=4e-20]} {Celegans: WBGene00018210, F39G3.5, [RH, Score=87.4, Expect=1e-20]} {Smed: dd_Smed_v6_4017_0_1, dd_Smed_v6_4017_0_1, [Score=118, Expect=2e-32]} {RNA1509_29638} {RNA1310_17515.1} {RNA815_8047}

Mlig455_062486 {REF} {Length: 1632} {Pfam: Eukaryotic cytochrome b561 [PF03188.18, score=113.3]} {Human: ENSG00000162144, CYB561A3, cytochrome b561 family member A3, [Score=122, Expect=5e-34]} {Mouse: ENSMUSG00000034445, Cyb561a3, cytochrome b561 family, member A3, [Score=124, Expect=4e-35]} {Dmel: FBgn0261673, nemy, no extended memory, [Score=83.6, Expect=8e-20]} {Celegans: WBGene00010131, F55H2.5, Putative cytochrome b561, [Score=84.3, Expect=8e-20]} {Smed: dd_Smed_v6_4017_0_1, dd_Smed_v6_4017_0_1, [Score=113, Expect=4e-31]} {RNA1509_29638, RNA1509_6916} {RNA1310_17515.1, RNA1509_29638} {RNA1509_29638, RNA815_8047}
22. MligTC455_49659 4741 98.77 Mlig455_011512, Mlig455_050003

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.314

Region-enriched R3: 1.923/0.00380

4.375 0.869 0.740 - 0.955 0.837 0.974

Mlig455_011512 {REF} {Length: 2299} {RNA1509_3964} {RNA1310_32368} {RNA815_14237.1}

Mlig455_050003 {REF} {Length: 1812} {RNA1509_3964} {RNA1310_32368} {RNA815_14237.1}
23. MligTC455_10784 1017 21.18 Mlig455_060178, Mlig455_067094

Neo: -

Age: Up-Down-Up

Region-enriched R4: 1.724/0.00469
Region-enriched R3: 1.524/0.00347

4.37 - 0.796 0.906 0.958 0.790 0.920

Mlig455_060178 {REF} {Length: 6205} {Pfam: Laminin G domain [PF02210.26, score=29.6]; Laminin G domain [PF00054.25, score=25.5]} {RNA1509_3538} {RNA1310_3085.1, RNA1509_3538} {RNA1509_3538, RNA815_1617}

Mlig455_067094 {REF} {Length: 4035} {Pfam: Laminin G domain [PF02210.26, score=29.6]; Laminin G domain [PF00054.25, score=25.5]} {RNA1509_3538, RNA1509_57795} {RNA1310_3085.1, RNA1509_57795} {RNA1509_57795, RNA815_1617}
24. MligTC455_52040 2198 45.8 Mlig455_029597

Neo: Germline

Age: logFC(26M/2M)=0.256

Region-enriched R3: 1.723/0.00072
Region-enriched R5: 1.481/0.00114

VIL1 4.37 0.801 0.885 0.746 0.962 - 0.976 Mlig455_029597 {REF} {Length: 2577} {Pfam: Gelsolin repeat [PF00626.24, score=113.7]} {Human: ENSG00000127831, VIL1, villin 1, [Score=182, Expect=5e-53]; ENSG00000148180, GSN, gelsolin, [Score=179, Expect=1e-49]; ENSG00000135407, AVIL, advillin, [Score=174, Expect=1e-47]} {Mouse: ENSMUSG00000026879, Gsn, gelsolin, [Score=185, Expect=7e-52]; ENSMUSG00000026175, Vil1, villin 1, [Score=182, Expect=1e-50]} {Dmel: FBgn0010225, Gel, Gelsolin, [Score=194, Expect=3e-55]} {Celegans: WBGene00010593, gsnl-1, Gelsolin-like protein 1, [Score=164, Expect=4e-46]} {Smed: dd_Smed_v6_1215_0_1, dd_Smed_v6_1215_0_1, [RH, Score=403, Expect=3e-140]} {RNA1509_12411, RNA1509_17911, RNA1509_2858, RNA1509_30271, RNA1509_44412, RNA1509_44633} {RNA1310_15610, RNA1509_12411, RNA1509_17911, RNA1509_2858, RNA1509_30271, RNA1509_44412, RNA1509_44633} {RNA1509_12411, RNA1509_17911, RNA1509_2858, RNA1509_30271, RNA1509_44412, RNA1509_44633, RNA815_7841}
25. MligTC455_37114 9548 198.91 Mlig455_020763

Neo: -

Age: -

Region-enriched R3: 1.051/0.01206

LGMN 4.368 0.832 0.755 0.897 0.958 - 0.926 Mlig455_020763 {REF} {Length: 1971} {Pfam: Peptidase C13 family [PF01650.20, score=360.1]} {Human: ENSG00000100600, LGMN, legumain, [RH, Score=386, Expect=4e-131]} {Mouse: ENSMUSG00000021190, Lgmn, legumain, [RH, Score=391, Expect=4e-133]} {Dmel: FBgn0023545, PIG-K, Phosphatidylinositol glycan anchor biosynthesis class K, [Score=126, Expect=2e-32]} {Celegans: WBGene00012144, T28H10.3, [RH, Score=323, Expect=2e-106]} {Smed: dd_Smed_v6_6456_0_1, dd_Smed_v6_6456_0_1, [Score=104, Expect=5e-25]} {RNA1509_4583} {RNA1310_13933, RNA1509_4583} {RNA1509_4583, RNA815_6243.1}
26. MligTC455_52041 2170 45.21 Mlig455_029621

Neo: -

Age: logFC(26M/2M)=0.515

Region-enriched R3: 1.780/0.00221
Region-enriched R5: 1.483/0.00437

SCIN 4.365 0.800 0.884 0.746 0.961 - 0.974 Mlig455_029621 {REF} {Length: 1419} {Pfam: Gelsolin repeat [PF00626.24, score=61.4]} {Human: ENSG00000006747, SCIN, scinderin, [Score=78.6, Expect=3e-15]} {Mouse: ENSMUSG00000002565, Scin, scinderin, [Score=82.8, Expect=7e-17]} {Dmel: FBgn0010225, Gel, Gelsolin, [Score=76.6, Expect=7e-15]} {Smed: dd_Smed_v6_1215_0_1, dd_Smed_v6_1215_0_1, [Score=214, Expect=8e-67]} {RNA1509_17911} {RNA1310_15610} {RNA815_7841}
27. MligTC455_15832 1195 24.9 Mlig455_048167

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.477

Region-enriched R4: 1.763/0.00304
Region-enriched R3: 1.641/0.00124
Region-enriched R5: 1.086/0.02606

4.363 - 0.830 0.889 0.958 0.787 0.899 Mlig455_048167 {REF} {Length: 3287} {Dmel: FBgn0033252, CG12769, [Score=60.1, Expect=2e-09]} {RNA1509_7124} {RNA1310_24518, RNA1509_7124} {RNA1509_7124, RNA815_12801}
28. MligTC455_52058 1280 26.66 Mlig455_041271

Neo: -

Age: logFC(26M/2M)=0.755

Region-enriched R3: 1.713/0.01206

4.357 0.865 0.806 - 0.970 0.773 0.943 Mlig455_041271 {REF} {Length: 2151} {Celegans: WBGene00015469, C05D2.8, [RH, Score=207, Expect=2e-62]} {Smed: dd_Smed_v6_8821_0_1, dd_Smed_v6_8821_0_1, [Score=159, Expect=8e-45]} {RNA1509_15031, RNA1509_21776, RNA1509_33962, RNA1509_54125, RNA1509_56588} {RNA1310_13148, RNA1509_15031, RNA1509_21776, RNA1509_33962, RNA1509_54125, RNA1509_56588} {RNA1509_15031, RNA1509_21776, RNA1509_33962, RNA1509_54125, RNA1509_56588, RNA815_7949}
29. MligTC455_24085 1786 37.2 Mlig455_007320

Neo: -

Age: logFC(26M/2M)=0.210

Region-enriched R3: 2.481/0.00000
Region-enriched R5: 1.136/0.04856

ACHE 4.313 0.899 0.860 - 0.981 0.763 0.810 Mlig455_007320 {REF} {Length: 2268} {Pfam: Carboxylesterase family [PF00135.30, score=353.8]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=232, Expect=2e-67]} {Mouse: ENSMUSG00000023328, Ache, acetylcholinesterase, [Score=227, Expect=1e-65]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=202, Expect=2e-56]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=223, Expect=2e-64]} {Smed: dd_Smed_v6_14790_0_1, dd_Smed_v6_14790_0_1, [Score=206, Expect=5e-58]} {RNA1509_28908, RNA1509_31228, RNA1509_46106} {RNA1310_10437.1, RNA1509_28908, RNA1509_31228, RNA1509_46106} {RNA1509_28908, RNA1509_31228, RNA1509_46106, RNA815_3976}
30. MligTC455_44700 2825 58.85 Mlig455_049079

Neo: -

Age: -

Region-enriched R3: 1.667/0.02565

SLC10A1 4.288 0.794 0.816 - 0.955 0.770 0.953 Mlig455_049079 {REF} {Length: 2131} {Pfam: Sodium Bile acid symporter family [PF01758.18, score=117.8]; SBF-like CPA transporter family (DUF4137) [PF13593.8, score=36.6]} {Human: ENSG00000100652, SLC10A1, solute carrier family 10 member 1, [RH, Score=124, Expect=4e-31]} {Mouse: ENSMUSG00000023073, Slc10a2, solute carrier family 10, member 2, [Score=131, Expect=1e-33]} {Dmel: FBgn0030638, CG11655, [Score=154, Expect=2e-41]} {Celegans: WBGene00044650, Y71G10AR.4, [RH, Score=202, Expect=9e-59]} {Smed: dd_Smed_v6_11330_0_1, dd_Smed_v6_11330_0_1, [RH, Score=297, Expect=9e-96]} {RNA1509_41454} {RNA1310_15046, RNA1509_41454} {RNA1509_41454, RNA815_3102}
31. MligTC455_50387 1074 22.38 Mlig455_018618

Neo: -

Age: logFC(26M/2M)=0.362

Region-enriched R4: 2.247/0.00001
Region-enriched R3: 1.935/0.00000

SLC8B1 4.272 0.792 0.834 - 0.956 0.745 0.945 Mlig455_018618 {REF} {Length: 2020} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=96.0]} {Human: ENSG00000089060, SLC8B1, solute carrier family 8 member B1, [RH, Score=214, Expect=1e-62]} {Mouse: ENSMUSG00000032754, Slc8b1, solute carrier family 8 (sodium/lithium/calcium exchanger), member B1, [RH, Score=220, Expect=4e-65]} {Dmel: FBgn0033324, CG14744, [Score=126, Expect=8e-31]} {Celegans: WBGene00003572, ncx-7, Putative sodium/calcium exchanger 7, [RH, Score=168, Expect=3e-45]} {Smed: dd_Smed_v6_1009_1_1, dd_Smed_v6_1009_1_1, [RH, Score=254, Expect=2e-80]} {RNA1509_17694, RNA1509_27887, RNA1509_3073} {RNA1310_3165.1, RNA1509_17694, RNA1509_27887} {RNA1509_17694, RNA1509_27887, RNA815_1390}
32. MligTC455_43800 4639 96.64 Mlig455_041018, Mlig455_041127, Mlig455_041183

Neo: -

Age: -

RGN 4.27 0.730 0.785 - 0.960 0.897 0.898

Mlig455_041018 {REF} {Length: 1500} {TRANSSPLICED} {Pfam: SMP-30/Gluconolactonase/LRE-like region [PF08450.14, score=221.4]; Two component regulator propeller [PF07494.13, score=22.9]} {Human: ENSG00000130988, RGN, regucalcin, [RH, Score=187, Expect=4e-57]} {Mouse: ENSMUSG00000023070, Rgn, regucalcin, [RH, Score=190, Expect=3e-58]} {Dmel: FBgn0030362, regucalcin, [Score=142, Expect=6e-40]} {Smed: dd_Smed_v6_3808_0_1, dd_Smed_v6_3808_0_1, [RH, Score=176, Expect=5e-53]} {RNA1509_3252} {RNA1310_20018.1} {RNA815_8819.1}

Mlig455_041127 {REF} {Length: 1500} {TRANSSPLICED} {Pfam: SMP-30/Gluconolactonase/LRE-like region [PF08450.14, score=216.7]; Two component regulator propeller [PF07494.13, score=22.9]} {Human: ENSG00000130988, RGN, regucalcin, [RH, Score=181, Expect=1e-54]} {Mouse: ENSMUSG00000023070, Rgn, regucalcin, [RH, Score=184, Expect=3e-56]} {Dmel: FBgn0038257, smp-30, Senescence marker protein-30, [Score=145, Expect=3e-41]} {Smed: dd_Smed_v6_3808_0_1, dd_Smed_v6_3808_0_1, [RH, Score=178, Expect=8e-54]} {RNA1509_3252} {RNA1310_7497.1} {RNA815_8819.1}

Mlig455_041183 {REF} {Length: 1502} {TRANSSPLICED} {Pfam: SMP-30/Gluconolactonase/LRE-like region [PF08450.14, score=216.7]; Two component regulator propeller [PF07494.13, score=22.9]} {Human: ENSG00000130988, RGN, regucalcin, [RH, Score=182, Expect=5e-55]} {Mouse: ENSMUSG00000023070, Rgn, regucalcin, [RH, Score=186, Expect=9e-57]} {Dmel: FBgn0038257, smp-30, Senescence marker protein-30, [Score=145, Expect=4e-41]} {Smed: dd_Smed_v6_3808_0_1, dd_Smed_v6_3808_0_1, [RH, Score=176, Expect=3e-53]} {RNA1509_3252} {RNA1310_7497.1} {RNA815_8819.1}
33. MligTC455_26167 4416 92 Mlig455_001635

Neo: -

Age: -

Region-enriched R3: 1.339/0.03044

TUBB2B 4.267 0.802 0.866 - 0.956 0.747 0.896 Mlig455_001635 {REF} {Length: 2122} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=239.0]; Tubulin C-terminal domain [PF03953.19, score=140.8]; Misato Segment II tubulin-like domain [PF10644.11, score=23.2]} {Human: ENSG00000137285, TUBB2B, tubulin beta 2B class IIb, [Score=814, Expect=0.0]; ENSG00000137267, TUBB2A, tubulin beta 2A class IIa, [Score=812, Expect=0.0]; ENSG00000196230, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000227739, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000235067, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000232421, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000224156, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000229684, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000183311, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000232575, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000188229, TUBB4B, tubulin beta 4B class IVb, [Score=811, Expect=0.0]; ENSG00000258947, TUBB3, tubulin beta 3 class III, [Score=803, Expect=0.0]; ENSG00000104833, TUBB4A, tubulin beta 4A class IVa, [Score=802, Expect=0.0]; ENSG00000176014, TUBB6, tubulin beta 6 class V, [Score=784, Expect=0.0]; ENSG00000261456, TUBB8, tubulin beta 8 class VIII, [Score=775, Expect=0.0]} {Mouse: ENSMUSG00000001473, Tubb6, tubulin, beta 6 class V, [RH, Score=788, Expect=0.0]} {Dmel: FBgn0284243, betaTub56D, beta-Tubulin at 56D, [Score=773, Expect=0.0]} {Celegans: WBGene00006537, tbb-2, Tubulin beta-2 chain, [Score=781, Expect=0.0]} {Smed: dd_Smed_v6_83_0_3, dd_Smed_v6_83_0_3, [Score=817, Expect=0.0]} {RNA1509_15718, RNA1509_19379, RNA1509_19747, RNA1509_30988, RNA1509_36839, RNA1509_41622, RNA1509_5016} {RNA1310_13968.2, RNA1509_15718, RNA1509_19379, RNA1509_19747, RNA1509_30988, RNA1509_36839, RNA1509_41622, RNA1509_5016} {RNA1509_15718, RNA1509_19379, RNA1509_19747, RNA1509_30988, RNA1509_36839, RNA1509_41622, RNA1509_5016, RNA815_1610.4}
34. MligTC455_43587 981 20.44 Mlig455_064849

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.445

Region-enriched R4: 1.141/0.04839

4.265 0.863 - 0.726 0.942 0.776 0.958 Mlig455_064849 {REF} {Length: 1597} {RNA1509_13829} {RNA1310_22619, RNA1509_13829} {RNA1509_13829, RNA815_12635}
35. MligTC455_46189 3465 72.19 Mlig455_064483

Neo: -

Age: -

Region-enriched R3: 2.108/0.00000
Region-enriched R4: 1.352/0.02878
Region-enriched R5: 1.186/0.01606

ENPEP 4.244 0.734 0.917 - 0.856 0.778 0.959 Mlig455_064483 {REF} {Length: 3574} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=253.3]; Peptidase family M1 domain [PF01433.22, score=243.6]; Peptidase M1 N-terminal domain [PF17900.3, score=149.2]} {Human: ENSG00000138792, ENPEP, glutamyl aminopeptidase, [RH, Score=590, Expect=0.0]} {Mouse: ENSMUSG00000028024, Enpep, glutamyl aminopeptidase, [RH, Score=590, Expect=0.0]} {Dmel: FBgn0038135, CG8773, [RH, Score=610, Expect=0.0]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=369, Expect=3e-112]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=479, Expect=2e-153]} {RNA1509_40879, RNA1509_41090, RNA1509_50042, RNA1509_56083, RNA1509_690, RNA1509_9985} {RNA1310_3977.1, RNA1509_40879, RNA1509_41090, RNA1509_50042, RNA1509_56083, RNA1509_690, RNA1509_9985} {RNA1509_40879, RNA1509_41090, RNA1509_50042, RNA1509_56083, RNA1509_690, RNA1509_9985, RNA815_1584}
36. MligTC455_17956 4052 84.43 Mlig455_033669, Mlig455_050146

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.218

Region-enriched R3: 1.577/0.00014
Region-enriched R4: 1.297/0.00873
Region-enriched R6: 1.274/0.01524
Region-enriched R5: 1.196/0.00285

AKR1B10 4.21 0.812 - 0.957 0.787 0.720 0.934

Mlig455_033669 {REF} {Length: 1299} {TRANSSPLICED} {Pfam: Aldo/keto reductase family [PF00248.23, score=179.4]} {Human: ENSG00000198074, AKR1B10, aldo-keto reductase family 1 member B10, [RH, Score=328, Expect=3e-112]; ENSG00000085662, AKR1B1, aldo-keto reductase family 1 member B, [RH, Score=328, Expect=6e-112]} {Mouse: ENSMUSG00000001642, Akr1b3, aldo-keto reductase family 1, member B3 (aldose reductase), [RH, Score=319, Expect=1e-108]; ENSMUSG00000028692, Akr1a1, aldo-keto reductase family 1, member A1 (aldehyde reductase), [RH, Score=306, Expect=1e-103]; ENSMUSG00000029762, Akr1b8, aldo-keto reductase family 1, member B8, [RH, Score=305, Expect=6e-103]} {Dmel: FBgn0086254, CG6084, [RH, Score=326, Expect=2e-111]} {Celegans: WBGene00012722, Y39G8B.1, [RH, Score=288, Expect=6e-97]} {Smed: dd_Smed_v6_9852_0_1, dd_Smed_v6_9852_0_1, [RH, Score=266, Expect=4e-88]} {RNA1509_6104} {RNA1310_15424} {RNA815_8072}

Mlig455_050146 {REF} {Length: 2314} {Pfam: Aldo/keto reductase family [PF00248.23, score=180.6]} {Human: ENSG00000198074, AKR1B10, aldo-keto reductase family 1 member B10, [RH, Score=329, Expect=2e-112]; ENSG00000085662, AKR1B1, aldo-keto reductase family 1 member B, [RH, Score=328, Expect=4e-112]} {Mouse: ENSMUSG00000001642, Akr1b3, aldo-keto reductase family 1, member B3 (aldose reductase), [RH, Score=319, Expect=1e-108]; ENSMUSG00000028692, Akr1a1, aldo-keto reductase family 1, member A1 (aldehyde reductase), [RH, Score=307, Expect=8e-104]; ENSMUSG00000029762, Akr1b8, aldo-keto reductase family 1, member B8, [RH, Score=305, Expect=3e-103]} {Dmel: FBgn0086254, CG6084, [RH, Score=326, Expect=1e-111]} {Celegans: WBGene00012722, Y39G8B.1, [RH, Score=289, Expect=4e-97]} {Smed: dd_Smed_v6_9852_0_1, dd_Smed_v6_9852_0_1, [RH, Score=266, Expect=3e-88]} {RNA1509_18580, RNA1509_20473, RNA1509_26383, RNA1509_6104} {RNA1310_15424, RNA1509_18580, RNA1509_20473, RNA1509_26383, RNA1509_6104} {RNA1509_18580, RNA1509_20473, RNA1509_26383, RNA1509_6104, RNA815_8072}
37. MligTC455_44102 5169 107.69 Mlig455_011991

Neo: -

Age: logFC(26M/2M)=0.278

Region-enriched R3: 1.948/0.00360
Region-enriched R4: 1.688/0.02863

HPGDS 4.199 0.812 - 0.842 0.871 0.713 0.961 Mlig455_011991 {REF} {Length: 1746} {Pfam: Glutathione S-transferase, C-terminal domain [PF14497.8, score=43.5]; Glutathione S-transferase, N-terminal domain [PF02798.22, score=42.8]; Glutathione S-transferase, N-terminal domain [PF13417.8, score=22.6]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=20.1]; Glutathione S-transferase, N-terminal domain [PF13409.8, score=19.1]} {Human: ENSG00000163106, HPGDS, hematopoietic prostaglandin D synthase, [Score=67.8, Expect=2e-13]} {Mouse: ENSMUSG00000025934, Gsta3, glutathione S-transferase, alpha 3, [Score=62.4, Expect=1e-11]; ENSMUSG00000032348, Gsta4, glutathione S-transferase, alpha 4, [Score=60.5, Expect=6e-11]; ENSMUSG00000029919, Hpgds, hematopoietic prostaglandin D synthase, [Score=60.5, Expect=5e-11]} {Celegans: WBGene00001756, gst-8, Probable glutathione S-transferase 8, [Score=84.0, Expect=5e-20]} {Smed: dd_Smed_v6_20_0_1, dd_Smed_v6_20_0_1, [Score=115, Expect=4e-32]} {RNA1509_2160, RNA1509_26612, RNA1509_28516, RNA1509_5091, RNA1509_6359} {RNA1310_14959.1, RNA1509_2160, RNA1509_26612, RNA1509_28516, RNA1509_5091, RNA1509_6359} {RNA1509_2160, RNA1509_26612, RNA1509_28516, RNA1509_5091, RNA1509_6359, RNA815_7403}
38. MligTC455_29886 979 20.4 Mlig455_029016

Neo: -

Age: logFC(26M/2M)=-0.339

Region-enriched R3: 1.707/0.00111

4.195 0.724 0.844 - 0.763 0.912 0.952 Mlig455_029016 {REF} {Length: 2165} {TRANSSPLICED} {Pfam: Innexin [PF00876.20, score=364.0]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=121, Expect=1e-30]} {Celegans: WBGene00006749, unc-9, Innexin unc-9, [Score=304, Expect=3e-100]} {Smed: dd_Smed_v6_734_0_1, dd_Smed_v6_734_0_1, [Score=305, Expect=3e-100]} {RNA1509_19970, RNA1509_32682, RNA1509_39326, RNA1509_47177, RNA1509_50541} {RNA1310_23805, RNA1509_19970, RNA1509_32682, RNA1509_39326, RNA1509_47177, RNA1509_50541} {RNA1509_19970, RNA1509_32682, RNA1509_39326, RNA1509_47177, RNA1509_50541, RNA815_9290}
39. MligTC455_44699 2074 43.2 Mlig455_048395

Neo: -

Age: logFC(26M/2M)=0.553

Region-enriched R3: 1.711/0.00637

SLC10A5 4.18 0.868 0.705 - 0.966 0.706 0.935 Mlig455_048395 {REF} {Length: 1771} {Pfam: Sodium Bile acid symporter family [PF01758.18, score=116.4]} {Human: ENSG00000253598, SLC10A5, solute carrier family 10 member 5, [RH, Score=130, Expect=9e-33]; ENSG00000100652, SLC10A1, solute carrier family 10 member 1, [RH, Score=125, Expect=2e-31]} {Mouse: ENSMUSG00000023073, Slc10a2, solute carrier family 10, member 2, [Score=129, Expect=4e-33]; ENSMUSG00000058921, Slc10a5, solute carrier family 10 (sodium/bile acid cotransporter family), member 5, [Score=125, Expect=6e-31]; ENSMUSG00000032806, Slc10a3, solute carrier family 10 (sodium/bile acid cotransporter family), member 3, [Score=124, Expect=9e-31]} {Dmel: FBgn0030756, CG9903, [Score=103, Expect=1e-23]} {Celegans: WBGene00044650, Y71G10AR.4, [RH, Score=206, Expect=4e-60]} {Smed: dd_Smed_v6_10199_0_1, dd_Smed_v6_10199_0_1, [RH, Score=295, Expect=3e-95]} {RNA1509_51285} {RNA1310_359.1} {RNA815_3102}
40. MligTC455_16062 635 13.22 Mlig455_026314

Neo: -

Age: logFC(26M/2M)=-0.923

Region-enriched R3: 2.095/0.00000
Region-enriched R4: 1.472/0.00808

SLC39A14 4.167 0.707 0.823 - 0.926 0.743 0.968 Mlig455_026314 {REF} {Length: 5567} {Pfam: ZIP Zinc transporter [PF02535.24, score=127.9]} {Human: ENSG00000104635, SLC39A14, solute carrier family 39 member 14, [Score=138, Expect=1e-36]} {Mouse: ENSMUSG00000022094, Slc39a14, solute carrier family 39 (zinc transporter), member 14, [Score=135, Expect=5e-36]} {Dmel: FBgn0036461, Zip71B, Zinc/iron regulated transporter-related protein 71B, [Score=95.5, Expect=1e-21]} {Celegans: WBGene00021936, zipt-20, Zrt (ZRT), Irt-(IRT-) like Protein Transporter, [Score=114, Expect=8e-29]} {Smed: dd_Smed_v6_8605_0_1, dd_Smed_v6_8605_0_1, [Score=162, Expect=2e-46]} {RNA1509_16476} {RNA1310_12919} {RNA815_5274}
41. MligTC455_45090 767 15.97 Mlig455_050942

Neo: -

Age: Down-Up-Down

Region-enriched R3: 1.666/0.00039
Region-enriched R4: 1.435/0.01328

NAAA 4.158 0.753 0.814 0.842 0.950 - 0.799 Mlig455_050942 {REF} {Length: 1563} {Pfam: beta subunit of N-acylethanolamine-hydrolyzing acid amidase [PF15508.8, score=40.2]; Linear amide C-N hydrolases, choloylglycine hydrolase family [PF02275.20, score=40.0]} {Human: ENSG00000138744, NAAA, N-acylethanolamine acid amidase, [RH, Score=243, Expect=5e-77]} {Mouse: ENSMUSG00000029413, Naaa, N-acylethanolamine acid amidase, [RH, Score=248, Expect=7e-79]} {Celegans: WBGene00021917, Y55D5A.3, [RH, Score=198, Expect=5e-60]} {RNA1509_56673} {RNA1310_22544, RNA1509_56673} {RNA1509_56673, RNA815_9551.1}
42. MligTC455_26883 1070 22.29 Mlig455_022052, Mlig455_062897

Neo: -

Age: Down-Down-Up

Region-enriched R3: 2.399/0.00450

B3GALT1 4.103 - 0.738 0.736 0.961 0.728 0.940

Mlig455_022052 {REF} {Length: 2065} {Pfam: Galactosyltransferase [PF01762.23, score=174.2]; Fringe-like [PF02434.18, score=20.2]} {Human: ENSG00000172318, B3GALT1, beta-1,3-galactosyltransferase 1, [RH, Score=133, Expect=3e-35]; ENSG00000183778, B3GALT5, beta-1,3-galactosyltransferase 5, [RH, Score=131, Expect=1e-34]} {Mouse: ENSMUSG00000034780, B3galt1, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1, [RH, Score=133, Expect=2e-35]; ENSMUSG00000074892, B3galt5, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5, [RH, Score=129, Expect=4e-34]} {Dmel: FBgn0035558, CG11357, [RH, Score=153, Expect=3e-42]} {Celegans: WBGene00008478, E03H4.11, Hexosyltransferase, [RH, Score=91.7, Expect=3e-20]} {Smed: dd_Smed_v6_4748_0_1, dd_Smed_v6_4748_0_1, [Score=177, Expect=4e-52]} {RNA1509_15518} {RNA1310_14003, RNA1509_15518} {RNA1509_15518, RNA815_5361.1}

Mlig455_062897 {REF} {Length: 2018} {Pfam: Galactosyltransferase [PF01762.23, score=170.1]} {Human: ENSG00000172318, B3GALT1, beta-1,3-galactosyltransferase 1, [RH, Score=131, Expect=2e-34]; ENSG00000183778, B3GALT5, beta-1,3-galactosyltransferase 5, [RH, Score=129, Expect=7e-34]} {Mouse: ENSMUSG00000034780, B3galt1, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1, [RH, Score=131, Expect=1e-34]; ENSMUSG00000074892, B3galt5, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5, [RH, Score=127, Expect=2e-33]} {Dmel: FBgn0035558, CG11357, [RH, Score=152, Expect=1e-41]} {Celegans: WBGene00009849, F48F7.3, Hexosyltransferase, [RH, Score=92.0, Expect=1e-20]} {Smed: dd_Smed_v6_18077_0_1, dd_Smed_v6_18077_0_1, [RH, Score=166, Expect=1e-48]} {RNA1509_15518} {RNA1310_14003} {RNA815_5361.1}
43. MligTC455_38075 513 10.69 Mlig455_037147

Neo: -

Age: Down-Down-Up

4.099 0.776 0.766 - 0.895 0.706 0.956 Mlig455_037147 {REF} {Length: 3140} {Pfam: Zona pellucida-like domain [PF00100.25, score=46.9]; Scavenger receptor cysteine-rich domain [PF00530.20, score=43.8]} {RNA1509_39101} {RNA1310_14098} {RNA815_2224.1}
44. MligTC455_38469 2237 46.61 Mlig455_028190, Mlig455_063554

Neo: -

Age: logFC(26M/2M)=0.551

Region-enriched R4: 2.765/0.00002
Region-enriched R3: 2.517/0.00000
Region-enriched R5: 1.859/0.00156

MFSD2A 3.69 0.926 0.861 - 0.972 - 0.931

Mlig455_028190 {REF} {Length: 1877} {Pfam: MFS/sugar transport protein [PF13347.8, score=314.5]; Major Facilitator Superfamily [PF07690.18, score=35.3]} {Human: ENSG00000168389, MFSD2A, major facilitator superfamily domain containing 2A, [RH, Score=317, Expect=2e-101]} {Mouse: ENSMUSG00000028655, Mfsd2a, major facilitator superfamily domain containing 2A, [RH, Score=312, Expect=2e-99]} {Smed: dd_Smed_v6_11210_0_1, dd_Smed_v6_11210_0_1, [RH, Score=380, Expect=3e-126]} {RNA1509_5264} {RNA1310_14549} {RNA815_5531}

Mlig455_063554 {REF} {Length: 2339} {Pfam: MFS/sugar transport protein [PF13347.8, score=217.9]; Major Facilitator Superfamily [PF07690.18, score=39.9]} {Human: ENSG00000168389, MFSD2A, major facilitator superfamily domain containing 2A, [RH, Score=223, Expect=1e-68]} {Mouse: ENSMUSG00000037336, Mfsd2b, major facilitator superfamily domain containing 2B, [RH, Score=212, Expect=2e-64]} {Smed: dd_Smed_v6_11210_0_1, dd_Smed_v6_11210_0_1, [Score=274, Expect=8e-87]} {RNA1509_5264} {RNA1310_14549} {RNA815_5531}
45. MligTC455_35217 5138 107.05 Mlig455_014282, Mlig455_014335

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.399

Region-enriched R3: 1.348/0.01129

3.678 0.929 0.808 - 0.988 - 0.953

Mlig455_014282 {REF} {Length: 1807} {TRANSSPLICED} {Pfam: Transferase family [PF02458.17, score=158.0]} {RNA1509_22501, RNA1509_4768} {RNA1310_7742.1, RNA1509_22501} {RNA1509_22501, RNA815_6411}

Mlig455_014335 {REF} {Length: 1769} {TRANSSPLICED} {Pfam: Transferase family [PF02458.17, score=159.5]} {RNA1509_4768} {RNA1310_7742.1} {RNA815_6411}
46. MligTC455_36727 2161 45.01 Mlig455_013407, Mlig455_013448

Neo: -

Age: logFC(26M/2M)=-0.438

Region-enriched R3: 1.447/0.00030

3.664 0.880 0.842 0.973 0.969 - -

Mlig455_013407 {REF} {Length: 3635} {RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611} {RNA1310_1688.1, RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611} {RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611, RNA815_14547}

Mlig455_013448 {REF} {Length: 3532} {RNA1509_17696} {RNA1310_1688.1} {RNA815_14547}
47. MligTC455_50448 759 15.81 Mlig455_064452

Neo: -

Age: logFC(26M/2M)=-0.850

KREMEN1 3.652 0.944 0.826 - 0.908 - 0.974 Mlig455_064452 {REF} {Length: 819} {Pfam: WSC domain [PF01822.21, score=61.7]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=52.4, Expect=9e-08]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=50.8, Expect=3e-08]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=53.9, Expect=1e-08]} {RNA1509_12393} {RNA1310_56240.1} {RNA815_26405}
48. MligTC455_24112 7326 152.63 Mlig455_006637, Mlig455_070643

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.380

CYP2D6, CYP2U1 3.624 - - 0.929 0.986 0.736 0.973

Mlig455_006637 {REF} {Length: 1777} {Pfam: Cytochrome P450 [PF00067.24, score=343.6]} {Human: ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=263, Expect=7e-81]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [RH, Score=263, Expect=2e-81]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [RH, Score=260, Expect=2e-80]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [RH, Score=259, Expect=4e-80]; ENSG00000275211, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=2e-79]; ENSG00000283284, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=1e-79]; ENSG00000100197, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=3e-79]; ENSG00000280905, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]; ENSG00000272532, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]; ENSG00000272000, AC236040.1, cytochrome P450 family 2 subfamily D member 6 pseudogene, [RH, Score=257, Expect=4e-79]; ENSG00000282966, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]} {Mouse: ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=285, Expect=3e-90]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [RH, Score=283, Expect=1e-89]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=278, Expect=2e-87]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=273, Expect=2e-85]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=271, Expect=8e-85]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=271, Expect=1e-84]} {Dmel: FBgn0001992, Cyp303a1, [RH, Score=207, Expect=1e-60]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [RH, Score=292, Expect=3e-93]} {RNA1509_10420} {RNA1310_15091.1} {RNA815_4606.2}

Mlig455_070643 {REF} {Length: 2371} {Pfam: Cytochrome P450 [PF00067.24, score=337.1]} {Human: ENSG00000283284, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=261, Expect=1e-80]; ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=260, Expect=7e-80]; ENSG00000275211, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=260, Expect=2e-80]; ENSG00000282966, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000272000, AC236040.1, cytochrome P450 family 2 subfamily D member 6 pseudogene, [RH, Score=259, Expect=3e-80]; ENSG00000272532, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000280905, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000100197, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [RH, Score=256, Expect=6e-79]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [RH, Score=254, Expect=3e-78]} {Mouse: ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=280, Expect=2e-88]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [RH, Score=279, Expect=7e-88]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=275, Expect=3e-86]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=268, Expect=1e-83]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=268, Expect=1e-83]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=266, Expect=7e-83]} {Dmel: FBgn0001992, Cyp303a1, [RH, Score=201, Expect=4e-58]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [RH, Score=288, Expect=2e-91]} {RNA1509_10420, RNA1509_36519} {RNA1310_15091.1, RNA1509_10420, RNA1509_36519} {RNA1509_10420, RNA1509_36519, RNA815_4606.2}
49. MligTC455_32901 454 9.47 Mlig455_067826

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.415

Region-enriched R3: 2.470/0.00379

CA7 3.592 - 0.827 0.873 0.916 - 0.976 Mlig455_067826 {REF} {Length: 1496} {Pfam: Eukaryotic-type carbonic anhydrase [PF00194.23, score=243.6]} {Human: ENSG00000168748, CA7, carbonic anhydrase 7, [RH, Score=207, Expect=8e-66]; ENSG00000133742, CA1, carbonic anhydrase 1, [RH, Score=197, Expect=1e-61]} {Mouse: ENSMUSG00000027562, Car2, carbonic anhydrase 2, [RH, Score=204, Expect=1e-64]} {Dmel: FBgn0027844, CAH1, Carbonic anhydrase 1, [Score=192, Expect=2e-60]} {Celegans: WBGene00000281, cah-3, Putative carbonic anhydrase 3, [RH, Score=137, Expect=2e-39]} {Smed: dd_Smed_v6_5784_0_1, dd_Smed_v6_5784_0_1, [Score=187, Expect=4e-58]} {RNA1509_23444, RNA1509_34487} {RNA1310_23047.1, RNA1509_23444, RNA1509_34487} {RNA1509_23444, RNA1509_34487, RNA815_11571.2}
50. MligTC455_18925 1222 25.47 Mlig455_034430

Neo: -

Age: Down-Up-Down

Region-enriched R4: 1.749/0.00485

RGS12 3.588 0.810 0.839 - 0.974 - 0.965 Mlig455_034430 {REF} {Length: 1569} {Pfam: Regulator of G protein signaling domain [PF00615.21, score=98.3]} {Human: ENSG00000159788, RGS12, regulator of G protein signaling 12, [Score=112, Expect=3e-26]; ENSG00000169220, RGS14, regulator of G protein signaling 14, [Score=110, Expect=6e-26]} {Mouse: ENSMUSG00000052087, Rgs14, regulator of G-protein signaling 14, [RH, Score=114, Expect=2e-27]} {Dmel: FBgn0020278, loco, locomotion defects, [Score=99.4, Expect=3e-22]} {Celegans: WBGene00004347, rgs-4, Regulator of G protein Signaling, [Score=82.8, Expect=3e-18]} {Smed: dd_Smed_v6_3873_0_1, dd_Smed_v6_3873_0_1, [Score=95.5, Expect=3e-23]} {RNA1509_7258} {RNA1310_21231} {RNA815_8874}
51. MligTC455_44136 8031 167.32 Mlig455_024689, Mlig455_024714

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=0.859

Region-enriched R4: 1.310/0.01340
Region-enriched R3: 1.215/0.02536

FADS2 3.572 - 0.897 0.818 0.883 - 0.974

Mlig455_024689 {REF} {Length: 3861} {TRANSSPLICED} {Pfam: Fatty acid desaturase [PF00487.26, score=116.9]; Cytochrome b5-like Heme/Steroid binding domain [PF00173.30, score=75.0]} {Human: ENSG00000134824, FADS2, fatty acid desaturase 2, [RH, Score=429, Expect=6e-148]; ENSG00000149485, FADS1, fatty acid desaturase 1, [RH, Score=426, Expect=8e-146]} {Mouse: ENSMUSG00000024665, Fads2, fatty acid desaturase 2, [RH, Score=446, Expect=7e-155]} {Dmel: FBgn0029854, CG3566, [Score=56.2, Expect=7e-10]} {Celegans: WBGene00001395, fat-3, Delta(6)-fatty-acid desaturase fat-3, [Score=130, Expect=2e-33]} {Smed: dd_Smed_v6_10869_0_1, dd_Smed_v6_10869_0_1, [Score=328, Expect=3e-109]} {RNA1509_1792, RNA1509_9754} {RNA1310_4526, RNA1509_1792, RNA1509_9754} {RNA1509_1792, RNA1509_9754, RNA815_4497}

Mlig455_024714 {REF} {Length: 5232} {TRANSSPLICED} {Pfam: Fatty acid desaturase [PF00487.26, score=117.3]; Cytochrome b5-like Heme/Steroid binding domain [PF00173.30, score=75.0]} {Human: ENSG00000134824, FADS2, fatty acid desaturase 2, [RH, Score=430, Expect=3e-148]; ENSG00000149485, FADS1, fatty acid desaturase 1, [RH, Score=427, Expect=2e-146]} {Mouse: ENSMUSG00000024665, Fads2, fatty acid desaturase 2, [RH, Score=447, Expect=3e-155]} {Dmel: FBgn0029854, CG3566, [Score=56.2, Expect=7e-10]} {Celegans: WBGene00001395, fat-3, Delta(6)-fatty-acid desaturase fat-3, [Score=130, Expect=2e-33]} {Smed: dd_Smed_v6_10869_0_1, dd_Smed_v6_10869_0_1, [Score=328, Expect=6e-109]} {RNA1509_9754} {RNA1310_4526} {RNA815_4497}
52. MligTC455_12470 343 7.15 Mlig455_015046

Neo: -

Age: Up-Down-Up

Region-enriched R4: 2.340/0.01759
Region-enriched R3: 2.177/0.01673

RAB35 3.554 - 0.856 0.853 0.953 - 0.892 Mlig455_015046 {REF} {Length: 937} {Pfam: Ras family [PF00071.24, score=126.3]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=89.6]; ADP-ribosylation factor family [PF00025.23, score=39.6]; RsgA GTPase [PF03193.18, score=34.0]; 50S ribosome-binding GTPase [PF01926.25, score=26.5]; Ethanolamine utilisation - propanediol utilisation [PF10662.11, score=25.0]; Elongation factor Tu GTP binding domain [PF00009.29, score=19.0]} {Human: ENSG00000111737, RAB35, RAB35, member RAS oncogene family, [Score=114, Expect=8e-31]; ENSG00000172794, RAB37, RAB37, member RAS oncogene family, [Score=110, Expect=6e-30]; ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [Score=109, Expect=3e-29]} {Mouse: ENSMUSG00000029518, Rab35, RAB35, member RAS oncogene family, [Score=114, Expect=5e-31]; ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [Score=110, Expect=1e-29]} {Dmel: FBgn0031090, Rab35, [Score=111, Expect=2e-30]} {Celegans: WBGene00004277, rab-18, Ras-related protein Rab-18, [Score=116, Expect=3e-32]} {Smed: dd_Smed_v6_2603_0_1, dd_Smed_v6_2603_0_1, [Score=125, Expect=1e-35]} {RNA1509_25152} {RNA1310_42493} {RNA815_19710}
53. MligTC455_19080 969 20.19 Mlig455_033341

Neo: -

Age: Up-Down-Down

Region-enriched R5: 1.378/0.02877

3.541 0.886 0.807 - 0.893 - 0.955 Mlig455_033341 {REF} {Length: 1009} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_41133} {RNA1310_2059.1} {RNA815_20560.2}
54. MligTC455_36665 2410 50.21 Mlig455_028654

Neo: -

Age: logFC(26M/2M)=0.273

Region-enriched R3: 1.404/0.00674

PSAP 3.528 - 0.820 - 0.991 0.775 0.942 Mlig455_028654 {REF} {Length: 3951} {Pfam: Saposin-like type B, region 1 [PF05184.17, score=340.1]; Saposin-like type B, region 2 [PF03489.19, score=316.5]; Homeodomain-like domain [PF13384.8, score=47.9]; Helix-turn-helix domain [PF13518.8, score=39.6]; Saposin A-type domain [PF02199.17, score=35.5]; Protein of unknown function (DUF2753) [PF10952.10, score=31.0]; Replication factor RFC1 C terminal domain [PF08519.14, score=24.2]; Winged helix-turn helix [PF13551.8, score=23.7]; HD domain [PF13023.8, score=21.9]; Delta endotoxin [PF18449.3, score=19.6]} {Human: ENSG00000197746, PSAP, prosaposin, [RH, Score=177, Expect=9e-47]} {Mouse: ENSMUSG00000004207, Psap, prosaposin, [RH, Score=154, Expect=6e-39]} {Dmel: FBgn0000416, Sap-r, Saposin-related, [RH, Score=245, Expect=3e-67]} {Smed: dd_Smed_v6_266_0_1, dd_Smed_v6_266_0_1, [Score=99.0, Expect=1e-22]} {RNA1509_1917} {RNA1310_9056} {RNA815_5033.1}
55. MligTC455_19955 2064 42.99 Mlig455_014277, Mlig455_014328

Neo: -

Age: -

Region-enriched R4: 1.732/0.00087
Region-enriched R5: 1.027/0.01771

PHYHD1 3.526 0.833 - 0.808 0.967 - 0.918

Mlig455_014277 {REF} {Length: 1311} {TRANSSPLICED} {Pfam: Phytanoyl-CoA dioxygenase (PhyH) [PF05721.15, score=178.4]} {Human: ENSG00000175287, PHYHD1, phytanoyl-CoA dioxygenase domain containing 1, [RH, Score=238, Expect=3e-77]} {Mouse: ENSMUSG00000079484, Phyhd1, phytanoyl-CoA dioxygenase domain containing 1, [RH, Score=232, Expect=1e-74]} {Dmel: FBgn0037819, CG14688, [RH, Score=205, Expect=1e-64]} {Celegans: WBGene00013650, Y105C5B.9, Phytanoyl-CoA dioxygenase domain-containing protein 1 homolog, [RH, Score=220, Expect=1e-70]} {Smed: dd_Smed_v6_8029_0_1, dd_Smed_v6_8029_0_1, [RH, Score=249, Expect=7e-82]} {RNA1509_18487} {RNA1310_28843.1} {RNA815_12227}

Mlig455_014328 {REF} {Length: 1306} {TRANSSPLICED} {Pfam: Phytanoyl-CoA dioxygenase (PhyH) [PF05721.15, score=178.5]} {Human: ENSG00000175287, PHYHD1, phytanoyl-CoA dioxygenase domain containing 1, [RH, Score=239, Expect=2e-77]} {Mouse: ENSMUSG00000079484, Phyhd1, phytanoyl-CoA dioxygenase domain containing 1, [RH, Score=233, Expect=6e-75]} {Dmel: FBgn0037819, CG14688, [RH, Score=204, Expect=2e-64]} {Celegans: WBGene00013650, Y105C5B.9, Phytanoyl-CoA dioxygenase domain-containing protein 1 homolog, [RH, Score=218, Expect=9e-70]} {Smed: dd_Smed_v6_8029_0_1, dd_Smed_v6_8029_0_1, [RH, Score=248, Expect=1e-81]} {RNA1509_18487} {RNA1310_28843.1} {RNA815_12227}
56. MligTC455_41283 1026 21.38 Mlig455_056291

Neo: -

Age: Down-Up-Up

Region-enriched R3: 2.480/0.00000
Region-enriched R4: 1.642/0.01172
Region-enriched R5: 1.330/0.01324

3.526 0.791 0.938 - 0.829 - 0.968 Mlig455_056291 {REF} {Length: 1075} {RNA1509_3034} {RNA1310_55537, RNA1509_3034} {RNA1509_3034, RNA815_28451}
57. MligTC455_50035 432 9 Mlig455_000039

Neo: -

Age: Up-Down-Up

Region-enriched R4: 2.574/0.01215

SPHK1 3.521 - 0.868 - 0.934 0.755 0.964 Mlig455_000039 {REF} {Length: 2459} {TRANSSPLICED} {Pfam: Diacylglycerol kinase catalytic domain [PF00781.26, score=79.4]; YegS C-terminal NAD kinase beta sandwich-like domain [PF19279.1, score=29.9]} {Human: ENSG00000176170, SPHK1, sphingosine kinase 1, [RH, Score=215, Expect=5e-64]} {Mouse: ENSMUSG00000061878, Sphk1, sphingosine kinase 1, [RH, Score=206, Expect=1e-60]} {Dmel: FBgn0030300, Sk1, Sphingosine kinase 1, [Score=142, Expect=1e-35]} {Celegans: WBGene00007918, sphk-1, Sphingosine kinase 1, [RH, Score=149, Expect=5e-39]} {Smed: dd_Smed_v6_5736_0_1, dd_Smed_v6_5736_0_1, [RH, Score=174, Expect=1e-48]} {RNA1509_19326} {RNA1310_4471} {RNA815_1161}
58. MligTC455_37843 1027 21.4 Mlig455_036229

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.713

Region-enriched R4: 2.635/0.00618
Region-enriched R5: 2.090/0.01009

3.508 0.846 0.840 - 0.966 0.856 - Mlig455_036229 {REF} {Length: 3170} {RNA1509_37071} {RNA1310_75243} {RNA815_10582}
59. MligTC455_22268 6636 138.25 Mlig455_011760

Neo: -

Age: logFC(26M/2M)=-0.323

Region-enriched R3: 1.908/0.00000
Region-enriched R6: 1.283/0.01830
Region-enriched R5: 1.133/0.00963

3.502 0.931 0.808 - 0.812 - 0.951 Mlig455_011760 {REF} {Length: 2561} {RNA1509_1433} {RNA1310_8428, RNA1509_1433} {RNA1509_1433, RNA815_2971}
60. MligTC455_41284 2517 52.44 Mlig455_056317

Neo: -

Age: -

Region-enriched R3: 2.272/0.00000

3.502 0.782 0.892 - 0.876 - 0.952 Mlig455_056317 {REF} {Length: 719} {RNA1509_3034} {RNA1310_55537} {RNA815_28451}
61. MligTC455_44530 352 7.33 Mlig455_038035

Neo: -

Age: Down-Up-Up

Region-enriched R3: 1.753/0.00110
Region-enriched R4: 1.598/0.01280
Region-enriched R5: 1.140/0.02561

3.498 0.720 0.853 - 0.947 - 0.978 Mlig455_038035 {REF} {Length: 1762} {Pfam: Universal stress protein family [PF00582.28, score=87.1]} {Smed: dd_Smed_v6_3388_0_1, dd_Smed_v6_3388_0_1, [Score=82.0, Expect=3e-20]} {RNA1509_59467} {RNA1310_35905, RNA1509_59467} {RNA1509_59467, RNA815_18113}
62. MligTC455_40294 928 19.33 Mlig455_062769

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.415

Region-enriched R4: 2.693/0.00000
Region-enriched R3: 1.531/0.00694
Region-enriched R5: 1.366/0.00671

VAV1 3.496 0.759 0.833 - 0.984 - 0.920 Mlig455_062769 {REF} {Length: 4319} {Pfam: SH2 domain [PF00017.26, score=34.9]; RhoGEF domain [PF00621.22, score=28.2]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=27.1]} {Human: ENSG00000141968, VAV1, vav guanine nucleotide exchange factor 1, [Score=93.6, Expect=5e-19]} {Mouse: ENSMUSG00000034116, Vav1, vav 1 oncogene, [Score=91.3, Expect=1e-18]} {Dmel: FBgn0040068, Vav, Vav guanine nucleotide exchange factor, [Score=61.2, Expect=2e-09]} {Celegans: WBGene00006887, vav-1, [Score=64.3, Expect=2e-10]} {RNA1509_11835} {RNA1310_8757} {RNA815_2576}
63. MligTC455_37973 1270 26.46 Mlig455_055227

Neo: -

Age: Down-Up-Up

Region-enriched R4: 1.059/0.03046

ASAH1 3.491 0.769 0.897 - 0.956 - 0.869 Mlig455_055227 {REF} {Length: 1456} {TRANSSPLICED} {Pfam: Linear amide C-N hydrolases, choloylglycine hydrolase family [PF02275.20, score=83.8]; beta subunit of N-acylethanolamine-hydrolyzing acid amidase [PF15508.8, score=40.2]} {Human: ENSG00000104763, ASAH1, N-acylsphingosine amidohydrolase 1, [Score=360, Expect=5e-122]} {Mouse: ENSMUSG00000031591, Asah1, N-acylsphingosine amidohydrolase 1, [Score=352, Expect=2e-119]} {Celegans: WBGene00010769, asah-1, Acid ceramidase, [Score=281, Expect=1e-91]} {RNA1509_25332, RNA1509_26010, RNA1509_9884} {RNA1310_24069.1, RNA1509_25332, RNA1509_26010, RNA1509_9884} {RNA1509_25332, RNA1509_26010, RNA1509_9884, RNA815_9637.1}
64. MligTC455_40293 973 20.27 Mlig455_003116

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.598

Region-enriched R4: 2.611/0.00000
Region-enriched R3: 1.603/0.00240
Region-enriched R5: 1.400/0.00374

VAV1 3.491 0.754 0.832 - 0.988 - 0.917 Mlig455_003116 {REF} {Length: 5727} {Pfam: SH2 domain [PF00017.26, score=32.8]; RhoGEF domain [PF00621.22, score=31.4]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=27.4]} {Human: ENSG00000141968, VAV1, vav guanine nucleotide exchange factor 1, [Score=95.1, Expect=2e-19]} {Mouse: ENSMUSG00000034116, Vav1, vav 1 oncogene, [Score=92.0, Expect=1e-18]} {Dmel: FBgn0040068, Vav, Vav guanine nucleotide exchange factor, [Score=65.1, Expect=2e-10]} {Celegans: WBGene00006887, vav-1, [Score=65.5, Expect=9e-11]} {RNA1509_11835} {RNA1310_8757} {RNA815_2576}
65. MligTC455_34295 1251 26.06 Mlig455_039417

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-1.176

Region-enriched R3: 2.357/0.00048
Region-enriched R4: 1.872/0.01857

3.49 0.881 0.776 - 0.880 - 0.953 Mlig455_039417 {REF} {Length: 666} {RNA1509_26409, RNA1509_26731, RNA1509_44065, RNA1509_51827} {RNA1310_54443, RNA1509_26409, RNA1509_26731, RNA1509_44065, RNA1509_51827} {RNA1509_26409, RNA1509_26731, RNA1509_44065, RNA1509_51827, RNA815_29054}
66. MligTC455_35936 4723 98.4 Mlig455_000144, Mlig455_067733

Neo: -

Age: logFC(26M/2M)=0.248

Region-enriched R5: 1.453/0.00004
Region-enriched R3: 1.201/0.00653
Region-enriched R4: 1.141/0.01645
Region-enriched R6: 1.062/0.04392

ALDH9A1 3.474 - - 0.934 0.971 0.709 0.860

Mlig455_000144 {REF} {Length: 1983} {TRANSSPLICED} {Pfam: Aldehyde dehydrogenase family [PF00171.24, score=528.7]; Protein of unknown function (DUF1487) [PF07368.13, score=18.5]} {Human: ENSG00000143149, ALDH9A1, aldehyde dehydrogenase 9 family member A1, [RH, Score=536, Expect=0.0]} {Mouse: ENSMUSG00000026687, Aldh9a1, aldehyde dehydrogenase 9, subfamily A1, [RH, Score=515, Expect=2e-179]} {Dmel: FBgn0012036, Aldh, Aldehyde dehydrogenase, [Score=350, Expect=4e-115]} {Celegans: WBGene00000118, alh-12, ALdehyde deHydrogenase, [RH, Score=458, Expect=1e-157]} {Smed: dd_Smed_v6_6827_0_1, dd_Smed_v6_6827_0_1, [RH, Score=530, Expect=0.0]} {RNA1509_2767} {RNA1310_13865, RNA1509_2767} {RNA1509_2767, RNA815_5064}

Mlig455_067733 {REF} {Length: 1983} {TRANSSPLICED} {Pfam: Aldehyde dehydrogenase family [PF00171.24, score=528.2]; Protein of unknown function (DUF1487) [PF07368.13, score=18.5]} {Human: ENSG00000143149, ALDH9A1, aldehyde dehydrogenase 9 family member A1, [RH, Score=535, Expect=0.0]} {Mouse: ENSMUSG00000026687, Aldh9a1, aldehyde dehydrogenase 9, subfamily A1, [RH, Score=514, Expect=8e-179]} {Dmel: FBgn0012036, Aldh, Aldehyde dehydrogenase, [Score=349, Expect=2e-114]} {Celegans: WBGene00000118, alh-12, ALdehyde deHydrogenase, [RH, Score=456, Expect=2e-156]} {Smed: dd_Smed_v6_6827_0_1, dd_Smed_v6_6827_0_1, [RH, Score=529, Expect=0.0]} {RNA1509_2767} {RNA1310_13865} {RNA815_5064}
67. MligTC455_09711 1548 32.26 Mlig455_029026

Neo: -

Age: -

ACO1 3.466 - - 0.741 0.972 0.801 0.952 Mlig455_029026 {REF} {Length: 4363} {Pfam: Aconitase family (aconitate hydratase) [PF00330.22, score=569.4]; Aconitase C-terminal domain [PF00694.21, score=140.7]; Ecdysteroid kinase-like family [PF02958.22, score=76.7]; Protein of unknown function (DUF1679) [PF07914.13, score=29.1]; Phosphotransferase enzyme family [PF01636.25, score=25.6]} {Human: ENSG00000122729, ACO1, aconitase 1, [Score=936, Expect=0.0]} {Mouse: ENSMUSG00000028405, Aco1, aconitase 1, [Score=903, Expect=0.0]} {Dmel: FBgn0024957, Irp-1B, Iron regulatory protein 1B, [Score=894, Expect=0.0]} {Celegans: WBGene00000040, aco-1, Probable cytoplasmic aconitate hydratase, [Score=845, Expect=0.0]} {Smed: dd_Smed_v6_979_0_1, dd_Smed_v6_979_0_1, [Score=148, Expect=2e-36]} {RNA1509_5220} {RNA1310_4609} {RNA815_1401.1}
68. MligTC455_22998 1192 24.84 Mlig455_001873, Mlig455_001948

Neo: -

Age: logFC(26M/2M)=0.334

Region-enriched R4: 2.809/0.00024
Region-enriched R3: 2.226/0.00227
Region-enriched R5: 1.925/0.00474

GATA4 3.465 - 0.849 - 0.974 0.703 0.939

Mlig455_001873 {REF} {Length: 2384} {Pfam: GATA zinc finger [PF00320.29, score=98.7]; TFIIB zinc-binding [PF08271.14, score=29.6]; Putative GTPase activating protein for Arf [PF01412.20, score=28.6]} {Human: ENSG00000285109, GATA4, GATA binding protein 4, [Score=172, Expect=6e-47]; ENSG00000136574, GATA4, GATA binding protein 4, [Score=172, Expect=6e-47]; ENSG00000141448, GATA6, GATA binding protein 6, [Score=166, Expect=1e-43]} {Mouse: ENSMUSG00000021944, Gata4, GATA binding protein 4, [Score=173, Expect=1e-47]; ENSMUSG00000005836, Gata6, GATA binding protein 6, [Score=165, Expect=1e-43]; ENSMUSG00000015627, Gata5, GATA binding protein 5, [Score=165, Expect=5e-45]} {Dmel: FBgn0003117, pnr, pannier, [Score=170, Expect=3e-46]} {Celegans: WBGene00001249, elt-1, Transcription factor elt-1, [Score=147, Expect=1e-38]} {Smed: dd_Smed_v6_4075_0_2, dd_Smed_v6_4075_0_2, [RH, Score=143, Expect=2e-36]} {RNA1509_43294} {RNA1310_15255} {RNA815_30190}

Mlig455_001948 {REF} {Length: 2519} {Pfam: GATA zinc finger [PF00320.29, score=98.7]; TFIIB zinc-binding [PF08271.14, score=29.6]; Putative GTPase activating protein for Arf [PF01412.20, score=28.1]} {Human: ENSG00000136574, GATA4, GATA binding protein 4, [Score=172, Expect=6e-47]; ENSG00000285109, GATA4, GATA binding protein 4, [Score=172, Expect=6e-47]; ENSG00000141448, GATA6, GATA binding protein 6, [Score=166, Expect=1e-43]} {Mouse: ENSMUSG00000021944, Gata4, GATA binding protein 4, [Score=172, Expect=2e-47]; ENSMUSG00000005836, Gata6, GATA binding protein 6, [Score=165, Expect=1e-43]; ENSMUSG00000015627, Gata5, GATA binding protein 5, [Score=165, Expect=5e-45]} {Dmel: FBgn0003117, pnr, pannier, [Score=170, Expect=3e-46]} {Celegans: WBGene00001249, elt-1, Transcription factor elt-1, [Score=146, Expect=2e-38]} {Smed: dd_Smed_v6_4075_0_1, dd_Smed_v6_4075_0_1, [RH, Score=143, Expect=1e-36]} {RNA1509_43294} {RNA1310_15255, RNA1509_43294} {RNA1509_43294, RNA815_30190}
69. MligTC455_20725 2475 51.57 Mlig455_035227

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.822

Region-enriched R3: 2.240/0.00003

SLC1A6 3.448 0.876 0.858 - 0.983 0.731 - Mlig455_035227 {REF} {Length: 2154} {Pfam: Sodium:dicarboxylate symporter family [PF00375.20, score=422.3]} {Human: ENSG00000105143, SLC1A6, solute carrier family 1 member 6, [RH, Score=462, Expect=2e-157]} {Mouse: ENSMUSG00000024935, Slc1a1, solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1, [RH, Score=456, Expect=3e-156]; ENSMUSG00000005357, Slc1a6, solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6, [RH, Score=452, Expect=1e-153]} {Dmel: FBgn0026439, Eaat1, Excitatory amino acid transporter 1, [RH, Score=373, Expect=3e-124]} {Celegans: WBGene00001620, glt-1, Excitatory amino acid transporter, [Score=422, Expect=3e-143]} {Smed: dd_Smed_v6_1106_0_1, dd_Smed_v6_1106_0_1, [Score=422, Expect=8e-144]} {RNA1509_7401} {RNA1310_8553.1, RNA1509_7401} {RNA1509_7401, RNA815_2974.1}
70. MligTC455_18869 1346 28.04 Mlig455_067491

Neo: -

Age: -

Region-enriched R3: 1.933/0.00397
Region-enriched R4: 1.775/0.01938
Region-enriched R5: 1.440/0.02287

3.421 0.709 - 0.748 0.975 - 0.989 Mlig455_067491 {REF} {Length: 2320} {Pfam: NAD dependent epimerase/dehydratase family [PF01370.23, score=72.5]; GDP-mannose 4,6 dehydratase [PF16363.7, score=51.3]; 3-beta hydroxysteroid dehydrogenase/isomerase family [PF01073.21, score=46.4]; Male sterility protein [PF07993.14, score=42.2]; NAD(P)H-binding [PF13460.8, score=39.3]; Polysaccharide biosynthesis protein [PF02719.17, score=30.0]; KR domain [PF08659.12, score=29.5]; NmrA-like family [PF05368.15, score=28.0]; short chain dehydrogenase [PF00106.27, score=19.3]} {Celegans: WBGene00017429, F13D11.4, [RH, Score=213, Expect=4e-66]} {RNA1509_20033, RNA1509_5037} {RNA1310_19379, RNA1509_20033, RNA1509_5037} {RNA1509_20033, RNA1509_5037, RNA815_6182.1}
71. MligTC455_19467 366 7.63 Mlig455_064830

Neo: -

Age: -

Region-enriched R4: 2.976/0.00386

TRPM6 3.414 - - 0.740 0.941 0.776 0.957 Mlig455_064830 {REF} {Length: 6830} {Pfam: SLOG in TRPM [PF18139.3, score=191.7]; SLOG in TRPM, prokaryote [PF18171.3, score=75.5]; Ion transport protein [PF00520.33, score=48.1]} {Human: ENSG00000119121, TRPM6, transient receptor potential cation channel subfamily M member 6, [Score=401, Expect=3e-115]} {Mouse: ENSMUSG00000030523, Trpm1, transient receptor potential cation channel, subfamily M, member 1, [RH, Score=416, Expect=2e-121]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=402, Expect=2e-119]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=323, Expect=1e-90]} {Smed: dd_Smed_v6_11259_0_12, dd_Smed_v6_11259_0_12, [RH, Score=498, Expect=4e-155]} {RNA1509_8221} {RNA1310_1347, RNA1509_8221} {RNA1509_8221, RNA815_794}
72. MligTC455_18868 1328 27.67 Mlig455_067483

Neo: -

Age: -

Region-enriched R3: 1.928/0.00492
Region-enriched R4: 1.837/0.01691
Region-enriched R5: 1.462/0.02245

3.412 0.711 - 0.739 0.974 - 0.988 Mlig455_067483 {REF} {Length: 405} {RNA1509_5037} {RNA1310_19379} {RNA815_6182.1}
73. MligTC455_41352 1305 27.18 Mlig455_037071

Neo: -

Age: Up-Down-Up

Region-enriched R4: 1.918/0.00007
Region-enriched R3: 1.036/0.03342

MOGAT2 3.411 - 0.788 0.729 0.951 - 0.943 Mlig455_037071 {REF} {Length: 866} {Pfam: Diacylglycerol acyltransferase [PF03982.15, score=209.7]} {Human: ENSG00000166391, MOGAT2, monoacylglycerol O-acyltransferase 2, [Score=189, Expect=9e-60]} {Mouse: ENSMUSG00000052396, Mogat2, monoacylglycerol O-acyltransferase 2, [Score=184, Expect=8e-57]} {Dmel: FBgn0033215, CG1942, [Score=154, Expect=4e-45]} {Celegans: WBGene00019464, K07B1.4, [Score=172, Expect=3e-52]} {Smed: dd_Smed_v6_4947_0_1, dd_Smed_v6_4947_0_1, [Score=154, Expect=1e-45]} {RNA1509_20138} {RNA1310_22626} {RNA815_11687.1}
74. MligTC455_48108 469 9.76 Mlig455_005110

Neo: -

Age: Down-Up-Up

SLC47A2 3.407 - 0.809 - 0.968 0.718 0.912 Mlig455_005110 {REF} {Length: 2550} {Pfam: MatE [PF01554.20, score=163.9]; Polysaccharide biosynthesis C-terminal domain [PF14667.8, score=29.8]} {Human: ENSG00000180638, SLC47A2, solute carrier family 47 member 2, [Score=294, Expect=7e-91]; ENSG00000142494, SLC47A1, solute carrier family 47 member 1, [Score=280, Expect=1e-85]} {Mouse: ENSMUSG00000010122, Slc47a1, solute carrier family 47, member 1, [Score=291, Expect=5e-90]; ENSMUSG00000069855, Slc47a2, solute carrier family 47, member 2, [Score=280, Expect=8e-86]} {Smed: dd_Smed_v6_11376_0_1, dd_Smed_v6_11376_0_1, [RH, Score=433, Expect=3e-145]} {RNA1509_37205} {RNA1310_8224.2, RNA1509_37205} {RNA1509_37205, RNA815_3210}
75. MligTC455_45590 6933 144.44 Mlig455_060243

Neo: -

Age: Up-Down-Down

Region-enriched R3: 1.918/0.00019

MRC1 3.404 0.824 0.778 - 0.965 - 0.837 Mlig455_060243 {REF} {Length: 4769} {Pfam: Lectin C-type domain [PF00059.23, score=548.8]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=62.0]; Extracellular link domain [PF00193.19, score=22.4]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [RH, Score=513, Expect=2e-156]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [RH, Score=485, Expect=1e-146]} {Dmel: FBgn0035199, tfc, triforce, [Score=57.4, Expect=8e-09]} {Celegans: WBGene00020191, clec-53, C-type LECtin, [RH, Score=103, Expect=1e-23]} {Smed: dd_Smed_v6_3193_0_2, dd_Smed_v6_3193_0_2, [Score=209, Expect=1e-54]} {RNA1509_169} {RNA1310_579} {RNA815_112.1}
76. MligTC455_37844 379 7.9 Mlig455_036230

Neo: -

Age: -

Region-enriched R4: 5.818/0.00000
Region-enriched R5: 2.587/0.03402

3.402 - - 0.713 0.962 0.837 0.890 Mlig455_036230 {REF} {Length: 331} {NoTransDecoderORF} {RNA1509_37071} {RNA1310_16369} {RNA815_10582}
77. MligTC455_16257 1877 39.1 Mlig455_026808, Mlig455_030881

Neo: -

Age: Down-Down-Up

Region-enriched R4: 2.209/0.00209
Region-enriched R3: 1.663/0.01717
Region-enriched R5: 1.364/0.02606

STOM 3.401 - 0.811 - 0.903 0.719 0.968

Mlig455_026808 {REF} {Length: 1301} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=20.6]} {Human: ENSG00000148175, STOM, stomatin, [Score=123, Expect=2e-35]; ENSG00000133115, STOML3, stomatin like 3, [Score=118, Expect=1e-33]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [Score=123, Expect=2e-35]; ENSMUSG00000027744, Stoml3, stomatin (Epb7.2)-like 3, [Score=120, Expect=2e-34]; ENSMUSG00000026602, Nphs2, nephrosis 2, podocin, [Score=117, Expect=2e-32]} {Dmel: FBgn0260657, CG42540, [Score=126, Expect=5e-36]} {Celegans: WBGene00006068, sto-6, STOmatin, [Score=140, Expect=1e-42]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [Score=148, Expect=1e-45]} {RNA1509_6816} {RNA1310_26895} {RNA815_11983}

Mlig455_030881 {REF} {Length: 1405} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=110.3]; SPFH domain-Band 7 family [PF13421.8, score=20.7]} {Human: ENSG00000148175, STOM, stomatin, [Score=335, Expect=3e-115]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [Score=323, Expect=5e-111]} {Dmel: FBgn0260657, CG42540, [Score=323, Expect=2e-109]} {Celegans: WBGene00003166, mec-2, Mechanosensory protein 2, [Score=335, Expect=4e-114]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [Score=362, Expect=1e-126]} {RNA1509_6816} {RNA1310_26895, RNA1509_6816} {RNA1509_6816, RNA815_11983}
78. MligTC455_23336 1585 33.01 Mlig455_007789

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.413

Region-enriched R3: 1.631/0.00000

3.399 0.965 0.822 - 0.719 - 0.893 Mlig455_007789 {REF} {Length: 2108} {Pfam: PLAC8 family [PF04749.19, score=74.3]} {Smed: dd_Smed_v6_743_0_1, dd_Smed_v6_743_0_1, [RH, Score=114, Expect=3e-34]} {RNA1509_26743, RNA1509_28154, RNA1509_5161} {RNA1310_50991, RNA1509_26743, RNA1509_28154} {RNA1509_26743, RNA1509_28154, RNA815_15567.2}
79. MligTC455_34688 756 15.75 Mlig455_049905

Neo: -

Age: logFC(26M/2M)=0.524

Region-enriched R3: 2.234/0.00031
Region-enriched R4: 1.743/0.02090
Region-enriched R5: 1.276/0.04216

MGAM2 3.386 - 0.805 0.736 0.891 - 0.954 Mlig455_049905 {REF} {Length: 4307} {Pfam: Glycosyl hydrolases family 31 [PF01055.28, score=486.1]; N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase [PF16863.7, score=39.1]; Galactose mutarotase-like [PF13802.8, score=25.5]} {Human: ENSG00000257743, MGAM2, maltase-glucoamylase 2 (putative), [Score=632, Expect=0.0]; ENSG00000278563, MGAM2, maltase-glucoamylase 2 (putative), [Score=632, Expect=0.0]; ENSG00000257335, MGAM, maltase-glucoamylase, [Score=626, Expect=0.0]; ENSG00000282607, MGAM, maltase-glucoamylase, [Score=617, Expect=0.0]; ENSG00000090402, SI, sucrase-isomaltase, [Score=605, Expect=0.0]} {Mouse: ENSMUSG00000068587, Mgam, maltase-glucoamylase, [Score=644, Expect=0.0]; ENSMUSG00000027790, Sis, sucrase isomaltase (alpha-glucosidase), [Score=631, Expect=0.0]} {Dmel: FBgn0027588, GCS2alpha, Glucosidase 2 alpha subunit, [Score=226, Expect=1e-61]} {Celegans: WBGene00017071, aagr-1, Acid Alpha Glucosidase Relate, [RH, Score=476, Expect=5e-153]} {Smed: dd_Smed_v6_1062_0_1, dd_Smed_v6_1062_0_1, [Score=530, Expect=2e-174]} {RNA1509_22266, RNA1509_2280, RNA1509_24970, RNA1509_29248, RNA1509_32202, RNA1509_33412} {RNA1310_4558.1, RNA1509_22266, RNA1509_2280, RNA1509_24970, RNA1509_29248, RNA1509_32202, RNA1509_33412} {RNA1509_22266, RNA1509_2280, RNA1509_24970, RNA1509_29248, RNA1509_32202, RNA1509_33412, RNA815_1348}
80. MligTC455_49840 1487 30.98 Mlig455_054770, Mlig455_054797

Neo: -

Age: -

Region-enriched R3: 1.670/0.00009
Region-enriched R5: 1.605/0.00002
Region-enriched R4: 1.351/0.01428

ECE1 3.384 0.728 0.854 - 0.974 - 0.828

Mlig455_054770 {REF} {Length: 3217} {Pfam: Peptidase family M13 [PF05649.15, score=200.5]; Peptidase family M13 [PF01431.23, score=91.3]} {Human: ENSG00000117298, ECE1, endothelin converting enzyme 1, [Score=179, Expect=1e-46]; ENSG00000142606, MMEL1, membrane metalloendopeptidase like 1, [Score=177, Expect=1e-45]; ENSG00000277131, MMEL1, membrane metalloendopeptidase like 1, [Score=177, Expect=1e-45]; ENSG00000171551, ECEL1, endothelin converting enzyme like 1, [Score=174, Expect=7e-45]} {Mouse: ENSMUSG00000058183, Mmel1, membrane metallo-endopeptidase-like 1, [Score=190, Expect=2e-50]} {Dmel: FBgn0029843, Nep1, Neprilysin 1, [Score=182, Expect=2e-47]} {Celegans: WBGene00020230, nep-2, Neprilysin-2, [Score=154, Expect=9e-39]} {Smed: dd_Smed_v6_1910_0_1, dd_Smed_v6_1910_0_1, [Score=160, Expect=7e-41]} {RNA1509_3125} {RNA1310_4911.1, RNA1509_3125} {RNA1509_3125, RNA815_2994}

Mlig455_054797 {REF} {Length: 3127} {Pfam: Peptidase family M13 [PF05649.15, score=200.5]; Peptidase family M13 [PF01431.23, score=92.9]} {Human: ENSG00000117298, ECE1, endothelin converting enzyme 1, [Score=182, Expect=2e-47]; ENSG00000142606, MMEL1, membrane metalloendopeptidase like 1, [Score=179, Expect=1e-46]; ENSG00000277131, MMEL1, membrane metalloendopeptidase like 1, [Score=179, Expect=1e-46]; ENSG00000171551, ECEL1, endothelin converting enzyme like 1, [Score=177, Expect=1e-45]; ENSG00000196549, MME, membrane metalloendopeptidase, [Score=173, Expect=1e-44]} {Mouse: ENSMUSG00000058183, Mmel1, membrane metallo-endopeptidase-like 1, [Score=193, Expect=2e-51]} {Dmel: FBgn0029843, Nep1, Neprilysin 1, [Score=184, Expect=3e-48]} {Celegans: WBGene00020230, nep-2, Neprilysin-2, [Score=157, Expect=1e-39]} {Smed: dd_Smed_v6_1910_0_1, dd_Smed_v6_1910_0_1, [Score=163, Expect=8e-42]} {RNA1509_3125} {RNA1310_4911.1} {RNA815_2994}
81. MligTC455_17186 498 10.38 Mlig455_066319

Neo: -

Age: -

Region-enriched R4: 3.693/0.00006
Region-enriched R3: 2.735/0.00030
Region-enriched R5: 2.267/0.00198

3.351 0.746 0.796 - 0.838 - 0.971 Mlig455_066319 {REF} {Length: 2762} {Pfam: YhhN family [PF07947.16, score=79.2]} {Dmel: FBgn0039681, CG7582, [Score=52.8, Expect=5e-08]} {Smed: dd_Smed_v6_11970_0_1, dd_Smed_v6_11970_0_1, [Score=64.3, Expect=2e-12]} {RNA1509_17539, RNA1509_20437, RNA1509_26581, RNA1509_28364} {RNA1310_11695.1, RNA1509_17539, RNA1509_20437, RNA1509_26581, RNA1509_28364} {RNA1509_17539, RNA1509_20437, RNA1509_26581, RNA1509_28364, RNA815_14610}
82. MligTC455_31670 1807 37.64 Mlig455_042472

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.652

Region-enriched R4: 2.167/0.00909
Region-enriched R3: 2.148/0.00292

3.35 0.767 0.866 - - 0.756 0.961 Mlig455_042472 {REF} {Length: 957} {RNA1509_3304, RNA1509_56059, RNA1509_6047} {RNA1310_18437, RNA1509_3304, RNA1509_56059, RNA1509_6047} {RNA1509_3304, RNA1509_56059, RNA1509_6047, RNA815_7167.1}
83. MligTC455_43406 1382 28.79 Mlig455_063546

Neo: -

Age: logFC(26M/2M)=-0.363

Region-enriched R4: 1.356/0.01589
Region-enriched R3: 1.139/0.04629

TRPA1 3.347 - 0.748 - 0.984 0.733 0.882 Mlig455_063546 {REF} {Length: 5889} {Pfam: Ion transport protein [PF00520.33, score=52.1]; Ankyrin repeat [PF00023.32, score=19.5]} {Human: ENSG00000104321, TRPA1, transient receptor potential cation channel subfamily A member 1, [Score=130, Expect=7e-30]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=127, Expect=5e-29]} {Dmel: FBgn0035934, TrpA1, Transient receptor potential cation channel A1, [Score=139, Expect=6e-33]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=153, Expect=2e-37]} {Smed: dd_Smed_v6_6201_0_2, dd_Smed_v6_6201_0_2, [Score=132, Expect=7e-31]} {RNA1509_21433, RNA1509_40381, RNA1509_43070, RNA1509_46763} {RNA1310_1768.1, RNA1509_21433, RNA1509_40381, RNA1509_43070} {RNA1509_21433, RNA1509_40381, RNA1509_43070, RNA815_3153}
84. MligTC455_33103 818 17.04 Mlig455_049936

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=0.704

Region-enriched R3: 1.236/0.01404

SLC47A1 3.341 - - 0.738 0.954 0.762 0.887 Mlig455_049936 {REF} {Length: 2568} {Pfam: MatE [PF01554.20, score=107.5]} {Human: ENSG00000142494, SLC47A1, solute carrier family 47 member 1, [Score=187, Expect=1e-51]} {Mouse: ENSMUSG00000069855, Slc47a2, solute carrier family 47, member 2, [Score=199, Expect=2e-56]; ENSMUSG00000010122, Slc47a1, solute carrier family 47, member 1, [Score=196, Expect=2e-55]} {Smed: dd_Smed_v6_8335_0_4, dd_Smed_v6_8335_0_4, [Score=212, Expect=3e-61]} {RNA1509_22002, RNA1509_22354, RNA1509_36610, RNA1509_39570} {RNA1310_12106.1, RNA1509_22002, RNA1509_22354, RNA1509_36610, RNA1509_39570} {RNA1509_22002, RNA1509_22354, RNA1509_36610, RNA1509_39570, RNA815_4765}
85. MligTC455_39157 503 10.49 Mlig455_037160, Mlig455_038477

Neo: -

Age: -

Region-enriched R4: 4.498/0.00000
Region-enriched R5: 2.369/0.01444

UNC93A 3.327 0.728 0.839 0.795 0.965 - -

Mlig455_037160 {REF} {Length: 1748} {Pfam: Major Facilitator Superfamily [PF07690.18, score=43.9]; Ion channel regulatory protein UNC-93 [PF05978.18, score=25.9]} {Human: ENSG00000112494, UNC93A, unc-93 homolog A, [Score=194, Expect=8e-56]} {Mouse: ENSMUSG00000067049, Unc93a, unc-93 homolog A, [Score=180, Expect=6e-51]; ENSMUSG00000056133, Unc93a2, unc-93 homolog A2, [Score=180, Expect=5e-51]} {Dmel: FBgn0027556, CG4928, [Score=215, Expect=6e-64]} {Celegans: WBGene00006822, unc-93, Putative potassium channel regulatory protein unc-93, [Score=162, Expect=4e-43]} {RNA1310_8603.1} {RNA815_11843}

Mlig455_038477 {REF} {Length: 1761} {Pfam: Major Facilitator Superfamily [PF07690.18, score=44.4]; Ion channel regulatory protein UNC-93 [PF05978.18, score=25.7]} {Human: ENSG00000112494, UNC93A, unc-93 homolog A, [Score=207, Expect=9e-61]} {Mouse: ENSMUSG00000056133, Unc93a2, unc-93 homolog A2, [Score=197, Expect=3e-57]; ENSMUSG00000067049, Unc93a, unc-93 homolog A, [Score=197, Expect=4e-57]} {Dmel: FBgn0027556, CG4928, [Score=234, Expect=4e-71]} {Celegans: WBGene00006822, unc-93, Putative potassium channel regulatory protein unc-93, [Score=166, Expect=2e-44]} {RNA1310_8603.1} {RNA815_11843}
86. MligTC455_48796 3932 81.93 Mlig455_010032, Mlig455_063287

Neo: -

Age: -

Region-enriched R3: 1.371/0.00023

3.32 0.787 0.722 - 0.848 - 0.963

Mlig455_010032 {REF} {Length: 3305} {TRANSSPLICED} {Dmel: FBgn0051195, CG31195, [RH, Score=445, Expect=3e-143]} {Smed: dd_Smed_v6_2407_0_1, dd_Smed_v6_2407_0_1, [RH, Score=727, Expect=0.0]} {RNA1509_1610, RNA1509_26475} {RNA1310_2842, RNA1509_1610, RNA1509_26475} {RNA1509_1610, RNA1509_26475, RNA815_1220.1}

Mlig455_063287 {REF} {Length: 3306} {TRANSSPLICED} {Dmel: FBgn0051195, CG31195, [RH, Score=445, Expect=4e-143]} {Smed: dd_Smed_v6_2407_0_1, dd_Smed_v6_2407_0_1, [RH, Score=726, Expect=0.0]} {RNA1509_1610} {RNA1310_2842} {RNA815_1220.1}
87. MligTC455_24083 6997 145.77 Mlig455_007319

Neo: -

Age: -

Region-enriched R3: 2.037/0.00010
Region-enriched R5: 1.165/0.04106

ACHE 3.317 0.771 0.817 0.760 - - 0.969 Mlig455_007319 {REF} {Length: 2399} {Pfam: Carboxylesterase family [PF00135.30, score=344.4]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=233, Expect=9e-68]} {Mouse: ENSMUSG00000023328, Ache, acetylcholinesterase, [Score=225, Expect=3e-65]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=183, Expect=6e-50]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=228, Expect=1e-66]} {Smed: dd_Smed_v6_4800_0_1, dd_Smed_v6_4800_0_1, [Score=184, Expect=4e-50]} {RNA1509_195, RNA1509_4270, RNA1509_51012} {RNA1310_9229, RNA1509_4270, RNA1509_51012} {RNA1509_4270, RNA1509_51012, RNA815_3141.1}
88. MligTC455_32761 994 20.72 Mlig455_031205

Neo: -

Age: Down-Down-Up

TTPAL 3.307 0.753 - 0.861 0.957 0.736 - Mlig455_031205 {REF} {Length: 1688} {Pfam: CRAL/TRIO domain [PF00650.22, score=52.1]} {Human: ENSG00000124120, TTPAL, alpha tocopherol transfer protein like, [Score=105, Expect=2e-25]; ENSG00000177182, CLVS1, clavesin 1, [Score=104, Expect=7e-25]; ENSG00000146352, CLVS2, clavesin 2, [Score=103, Expect=1e-24]} {Mouse: ENSMUSG00000017679, Ttpal, tocopherol (alpha) transfer protein-like, [Score=107, Expect=5e-26]; ENSMUSG00000019785, Clvs2, clavesin 2, [Score=103, Expect=4e-25]; ENSMUSG00000041216, Clvs1, clavesin 1, [Score=103, Expect=1e-24]} {Dmel: FBgn0036289, CG10657, [Score=114, Expect=5e-29]} {Smed: dd_Smed_v6_3680_0_1, dd_Smed_v6_3680_0_1, [Score=220, Expect=5e-69]} {RNA1509_52690} {RNA1310_22590.1} {RNA815_11166}
89. MligTC455_19366 2365 49.28 Mlig455_029830

Neo: -

Age: -

Region-enriched R3: 1.992/0.00057
Region-enriched R5: 1.418/0.01296

PANK3 3.302 0.757 - 0.818 0.989 0.738 - Mlig455_029830 {REF} {Length: 1495} {Pfam: Fumble [PF03630.16, score=108.9]} {Human: ENSG00000120137, PANK3, pantothenate kinase 3, [Score=57.0, Expect=2e-08]; ENSG00000152782, PANK1, pantothenate kinase 1, [Score=56.6, Expect=3e-08]; ENSG00000125779, PANK2, pantothenate kinase 2, [Score=55.1, Expect=5e-08]} {Mouse: ENSMUSG00000018846, Pank3, pantothenate kinase 3, [Score=56.6, Expect=2e-08]; ENSMUSG00000033610, Pank1, pantothenate kinase 1, [Score=56.2, Expect=2e-08]; ENSMUSG00000037514, Pank2, pantothenate kinase 2, [Score=55.8, Expect=4e-08]} {Dmel: FBgn0011205, fbl, fumble, [Score=55.1, Expect=5e-08]} {Smed: dd_Smed_v6_994_0_1, dd_Smed_v6_994_0_1, [RH, Score=227, Expect=2e-71]} {RNA1509_1801} {RNA1310_24657, RNA1509_1801} {RNA1509_1801, RNA815_10326}
90. MligTC455_53878 8131 169.39 Mlig455_056351

Neo: -

Age: logFC(26M/2M)=0.398

Region-enriched R3: 1.950/0.00000
Region-enriched R5: 1.089/0.01986

CLCA1 3.295 0.716 0.836 - 0.784 - 0.959 Mlig455_056351 {REF} {Length: 4429} {Pfam: Calcium-activated chloride channel N terminal [PF08434.13, score=166.8]; von Willebrand factor type A domain [PF00092.30, score=30.4]; von Willebrand factor type A domain [PF13519.8, score=27.0]; von Willebrand factor type A domain [PF13768.8, score=23.5]} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [Score=166, Expect=2e-41]} {Mouse: ENSMUSG00000028255, Clca1, chloride channel accessory 1, [Score=165, Expect=5e-41]} {Celegans: WBGene00018026, F35A5.4, [Score=58.2, Expect=3e-08]} {RNA1509_656} {RNA1310_5461.1} {RNA815_1665}
91. MligTC455_20060 2538 52.87 Mlig455_063008

Neo: -

Age: logFC(26M/2M)=0.327

AMT 3.293 0.818 - - 0.951 0.716 0.808 Mlig455_063008 {REF} {Length: 1813} {TRANSSPLICED} {Pfam: Aminomethyltransferase folate-binding domain [PF01571.23, score=260.3]; Glycine cleavage T-protein C-terminal barrel domain [PF08669.13, score=63.7]} {Human: ENSG00000145020, AMT, aminomethyltransferase, [RH, Score=337, Expect=6e-113]} {Mouse: ENSMUSG00000032607, Amt, aminomethyltransferase, [RH, Score=341, Expect=2e-114]} {Dmel: FBgn0032287, CG6415, [RH, Score=308, Expect=9e-102]} {Celegans: WBGene00017765, gcst-1, Aminomethyltransferase, [RH, Score=298, Expect=6e-98]} {Smed: dd_Smed_v6_3994_0_1, dd_Smed_v6_3994_0_1, [RH, Score=346, Expect=1e-116]} {RNA1509_21672} {RNA1310_17248.1} {RNA815_1503.1}
92. MligTC455_20726 1772 36.91 Mlig455_035274

Neo: -

Age: -

Region-enriched R3: 2.119/0.00009

SLC1A6 3.285 0.754 0.826 - 0.974 0.731 - Mlig455_035274 {REF} {Length: 2086} {Pfam: Sodium:dicarboxylate symporter family [PF00375.20, score=422.3]} {Human: ENSG00000105143, SLC1A6, solute carrier family 1 member 6, [RH, Score=462, Expect=9e-158]} {Mouse: ENSMUSG00000024935, Slc1a1, solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1, [RH, Score=457, Expect=3e-156]; ENSMUSG00000005357, Slc1a6, solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6, [RH, Score=452, Expect=6e-154]} {Dmel: FBgn0026439, Eaat1, Excitatory amino acid transporter 1, [RH, Score=373, Expect=4e-124]} {Celegans: WBGene00001620, glt-1, Excitatory amino acid transporter, [Score=421, Expect=6e-143]} {Smed: dd_Smed_v6_1106_0_1, dd_Smed_v6_1106_0_1, [Score=427, Expect=2e-145]} {RNA1509_5272, RNA1509_57758, RNA1509_7401} {RNA1310_8553.1, RNA1509_5272, RNA1509_57758} {RNA1509_5272, RNA1509_57758, RNA815_2974.1}
93. MligTC455_37964 3298 68.72 Mlig455_056045

Neo: -

Age: logFC(26M/2M)=1.465

HSD17B4 3.274 0.797 - - 0.805 0.720 0.952 Mlig455_056045 {REF} {Length: 2688} {Pfam: short chain dehydrogenase [PF00106.27, score=134.8]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=112.0]; MaoC like domain [PF01575.21, score=101.4]; SCP-2 sterol transfer family [PF02036.19, score=70.6]; KR domain [PF08659.12, score=53.8]} {Human: ENSG00000133835, HSD17B4, hydroxysteroid 17-beta dehydrogenase 4, [RH, Score=810, Expect=0.0]} {Mouse: ENSMUSG00000024507, Hsd17b4, hydroxysteroid (17-beta) dehydrogenase 4, [RH, Score=781, Expect=0.0]} {Dmel: FBgn0030731, Mfe2, peroxisomal Multifunctional enzyme type 2, [RH, Score=595, Expect=0.0]} {Celegans: WBGene00000991, dhs-28, DeHydrogenases, Short chain, [RH, Score=358, Expect=1e-116]} {Smed: dd_Smed_v6_5867_0_1, dd_Smed_v6_5867_0_1, [RH, Score=605, Expect=0.0]} {RNA1509_9012} {RNA1310_590.1} {RNA815_2204}
94. MligTC455_37965 2119 44.14 Mlig455_061609

Neo: -

Age: logFC(26M/2M)=-0.234

Region-enriched R4: 1.829/0.00050
Region-enriched R5: 1.117/0.01344

HSD17B4 3.255 - - 0.809 0.782 0.713 0.951 Mlig455_061609 {REF} {Length: 2731} {TRANSSPLICED} {Pfam: short chain dehydrogenase [PF00106.27, score=134.8]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=111.9]; MaoC like domain [PF01575.21, score=97.6]; KR domain [PF08659.12, score=53.8]; SCP-2 sterol transfer family [PF02036.19, score=48.6]} {Human: ENSG00000133835, HSD17B4, hydroxysteroid 17-beta dehydrogenase 4, [RH, Score=778, Expect=0.0]} {Mouse: ENSMUSG00000024507, Hsd17b4, hydroxysteroid (17-beta) dehydrogenase 4, [RH, Score=754, Expect=0.0]} {Dmel: FBgn0030731, Mfe2, peroxisomal Multifunctional enzyme type 2, [RH, Score=591, Expect=0.0]} {Celegans: WBGene00000991, dhs-28, DeHydrogenases, Short chain, [RH, Score=358, Expect=1e-116]} {Smed: dd_Smed_v6_5867_0_1, dd_Smed_v6_5867_0_1, [RH, Score=605, Expect=0.0]} {RNA1509_1653, RNA1509_23131, RNA1509_39124, RNA1509_9012} {RNA1310_590.1, RNA1509_1653, RNA1509_23131, RNA1509_39124, RNA1509_9012} {RNA1509_1653, RNA1509_23131, RNA1509_39124, RNA1509_9012, RNA815_2204}
95. MligTC455_45315 4773 99.43 Mlig455_037736

Neo: -

Age: -

3.24 - 0.763 - 0.724 0.769 0.984 Mlig455_037736 {REF} {Length: 2269} {RNA1509_18494, RNA1509_5801} {RNA1310_12524.1, RNA1509_5801} {RNA1509_5801, RNA815_3944.1}
96. MligTC455_16064 205 4.27 Mlig455_026327

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.743

Region-enriched R3: 2.239/0.00850

SLC39A14 3.183 - 0.722 - 0.794 0.710 0.957 Mlig455_026327 {REF} {Length: 2551} {Pfam: ZIP Zinc transporter [PF02535.24, score=177.4]} {Human: ENSG00000104635, SLC39A14, solute carrier family 39 member 14, [Score=187, Expect=6e-53]; ENSG00000196950, SLC39A10, solute carrier family 39 member 10, [Score=179, Expect=2e-48]} {Mouse: ENSMUSG00000022094, Slc39a14, solute carrier family 39 (zinc transporter), member 14, [Score=184, Expect=4e-52]} {Dmel: FBgn0036461, Zip71B, Zinc/iron regulated transporter-related protein 71B, [Score=144, Expect=3e-37]} {Celegans: WBGene00021936, zipt-20, Zrt (ZRT), Irt-(IRT-) like Protein Transporter, [Score=160, Expect=3e-44]} {Smed: dd_Smed_v6_8605_0_1, dd_Smed_v6_8605_0_1, [Score=213, Expect=2e-63]} {RNA1509_16476} {RNA1310_11294, RNA1509_16476} {RNA1509_16476, RNA815_5274}
97. MligTC455_48012 225 4.68 Mlig455_021532

Neo: -

Age: Down-Up-Down

Region-enriched R3: 2.619/0.00051

3.159 0.733 0.718 - 0.719 - 0.989 Mlig455_021532 {REF} {Length: 854} {Celegans: WBGene00044743, crb-3, Drosophila CRumBs homolog, [RH, Score=44.7, Expect=2e-07]} {RNA1509_16097} {RNA1310_12897} {RNA815_7368}
98. MligTC455_18866 706 14.71 Mlig455_027285

Neo: -

Age: Down-Up-Down

3.149 0.705 0.708 - - 0.771 0.965 Mlig455_027285 {REF} {Length: 736} {RNA1509_12836} {RNA1310_17576.2} {RNA815_6182.1}
99. MligTC455_50091 3389 70.6 Mlig455_041940

Neo: -

Age: logFC(26M/2M)=0.438

CAT 2.806 - - 0.930 0.924 - 0.952 Mlig455_041940 {REF} {Length: 2013} {TRANSSPLICED} {Pfam: Catalase [PF00199.21, score=645.7]; Catalase-related immune-responsive [PF06628.14, score=80.3]} {Human: ENSG00000121691, CAT, catalase, [RH, Score=744, Expect=0.0]} {Mouse: ENSMUSG00000027187, Cat, catalase, [RH, Score=744, Expect=0.0]} {Dmel: FBgn0000261, Cat, Catalase, [RH, Score=704, Expect=0.0]} {Celegans: WBGene00000831, ctl-2, Peroxisomal catalase 1, [RH, Score=635, Expect=0.0]} {Smed: dd_Smed_v6_859_0_1, dd_Smed_v6_859_0_1, [RH, Score=640, Expect=0.0]} {RNA1509_2448, RNA1509_24848} {RNA1310_13356.1, RNA1509_2448, RNA1509_24848} {RNA1509_2448, RNA1509_24848, RNA815_4899.1}
100. MligTC455_39261 2000 41.67 Mlig455_036509, Mlig455_069140

Neo: -

Age: logFC(26M/2M)=-0.812

2.805 0.918 - - 0.911 - 0.976

Mlig455_036509 {REF} {Length: 2142} {RNA1509_28747} {RNA1310_48185.2} {RNA815_28254}

Mlig455_069140 {REF} {Length: 3743} {RNA1509_28747, RNA1509_33325, RNA1509_34343} {RNA1310_46864, RNA1509_28747, RNA1509_33325, RNA1509_34343} {RNA1509_28747, RNA1509_33325, RNA1509_34343, RNA815_28254}

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