Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_49362 | 929 | 19.36 | Mlig455_034948 | Neo: Int S/G2/M Age: - Region-enriched R5: 2.608/0.00000 Regeneration-enriched TP: 4.706 |
FGFR1OP | Mlig455_034948 {REF} {Length: 944} {Pfam: FOP N terminal dimerisation domain [PF09398.12, score=26.5]} {Human: ENSG00000213066, FGFR1OP, FGFR1 oncogene partner, [Score=81.6, Expect=4e-18]} {Mouse: ENSMUSG00000069135, Fgfr1op, Fgfr1 oncogene partner, [Score=79.3, Expect=2e-17]} {Smed: dd_Smed_v6_5371_0_1, dd_Smed_v6_5371_0_1, [RH, Score=68.6, Expect=3e-14]} {RNA1509_35328} {RNA1310_39832.1} {RNA815_19196} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -1.604 | 4.567 | 0.99549 | 1.00000 | |
RegionR2 | 0.713 | 4.567 | 0.29876 | 0.68751 | |
RegionR3 | 0.903 | 4.567 | 0.14697 | 0.65182 | |
RegionR4 | 2.354 | 4.567 | 0.00000 | 0.00003 | |
RegionR5 | 2.608 | 4.567 | 0.00000 | 0.00000 | |
RegionR6 | 2.038 | 4.567 | 0.00003 | 0.00315 | |
RegionR7 | 0.684 | 4.567 | 0.34795 | 0.98525 | |
RegionR8 | -7.695 | 4.567 | 0.00011 | 0.00904 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | 1.251 | 4.567 | 0.46525 | 1.00000 | |
RegenerationR2 | 0.521 | 4.567 | 0.13370 | 0.56054 | |
RegenerationR3 | 0.851 | 4.567 | 0.02285 | 0.27349 | |
RegenerationR4 | 0.03 | 4.567 | 0.93073 | 1.00000 | |
RegenerationR5 | 0.086 | 4.567 | 0.77777 | 0.98115 | |
RegenerationR6 | 0.052 | 4.567 | 0.88229 | 1.00000 | |
RegenerationBL | 3.427 | 4.567 | 0.00001 | 0.00079 | |
RegenerationTP | 4.706 | 4.567 | 0.00001 | 0.00223 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_49362 | 929 | 19.36 | Mlig455_034948 | Neo: Int S/G2/M Age: - Region-enriched R5: 2.608/0.00000 Regeneration-enriched TP: 4.706 |
FGFR1OP | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_034948 {REF} {Length: 944} {Pfam: FOP N terminal dimerisation domain [PF09398.12, score=26.5]} {Human: ENSG00000213066, FGFR1OP, FGFR1 oncogene partner, [Score=81.6, Expect=4e-18]} {Mouse: ENSMUSG00000069135, Fgfr1op, Fgfr1 oncogene partner, [Score=79.3, Expect=2e-17]} {Smed: dd_Smed_v6_5371_0_1, dd_Smed_v6_5371_0_1, [RH, Score=68.6, Expect=3e-14]} {RNA1509_35328} {RNA1310_39832.1} {RNA815_19196} |
2. | MligTC455_29794 | 13232 | 275.67 | Mlig455_008533, Mlig455_023375, Mlig455_068951 | Neo: Neoblast, stringent Age: Down-Up-Up, logFC(26M/2M)=0.338 Regeneration-upregulated BL: 1.258 Regeneration-enriched BL: 1.258 |
DDX39B | 1.726 | - | - | 0.776 | - | - | 0.950 | Mlig455_008533 {REF} {Length: 1439} Mlig455_023375 {REF} {Length: 1739} {TRANSSPLICED} {Pfam: DEAD/DEAH box helicase [PF00270.31, score=141.2]; Helicase conserved C-terminal domain [PF00271.33, score=92.8]; U3-containing 90S pre-ribosomal complex subunit [PF14617.8, score=33.4]; Type III restriction enzyme, res subunit [PF04851.17, score=29.8]} {Human: ENSG00000198563, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000229496, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000235439, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000225859, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000230624, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000215425, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000225073, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000123136, DDX39A, DExD-box helicase 39A, [RH, Score=701, Expect=0.0]} {Mouse: ENSMUSG00000019432, Ddx39b, DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B, [RH, Score=716, Expect=0.0]; ENSMUSG00000005481, Ddx39, DEAD (Asp-Glu-Ala-Asp) box polypeptide 39, [RH, Score=703, Expect=0.0]} {Dmel: FBgn0014189, Hel25E, Helicase at 25E, [RH, Score=699, Expect=0.0]} {Celegans: WBGene00001840, hel-1, Spliceosome RNA helicase DDX39B homolog, [RH, Score=655, Expect=0.0]} {Smed: dd_Smed_v6_724_0_1, dd_Smed_v6_724_0_1, [RH, Score=714, Expect=0.0]} {RNA1509_16673} {RNA1310_11845, RNA1509_16673} {RNA1509_16673, RNA815_6753} Mlig455_068951 {REF} {Length: 1734} {TRANSSPLICED} {Pfam: DEAD/DEAH box helicase [PF00270.31, score=141.2]; Helicase conserved C-terminal domain [PF00271.33, score=92.8]; U3-containing 90S pre-ribosomal complex subunit [PF14617.8, score=33.4]; Type III restriction enzyme, res subunit [PF04851.17, score=29.8]} {Human: ENSG00000225859, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000235439, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000215425, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000225073, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000198563, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000229496, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000230624, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000123136, DDX39A, DExD-box helicase 39A, [RH, Score=699, Expect=0.0]} {Mouse: ENSMUSG00000019432, Ddx39b, DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B, [RH, Score=716, Expect=0.0]; ENSMUSG00000005481, Ddx39, DEAD (Asp-Glu-Ala-Asp) box polypeptide 39, [RH, Score=703, Expect=0.0]} {Dmel: FBgn0014189, Hel25E, Helicase at 25E, [RH, Score=699, Expect=0.0]} {Celegans: WBGene00001840, hel-1, Spliceosome RNA helicase DDX39B homolog, [RH, Score=654, Expect=0.0]} {Smed: dd_Smed_v6_724_0_1, dd_Smed_v6_724_0_1, [RH, Score=713, Expect=0.0]} {RNA1509_16673} {RNA1310_11845} {RNA815_6753} |
3. | MligTC455_36145 | 2577 | 53.69 | Mlig455_029420 | Neo: Neoblast, stringent Age: logFC(26M/2M)=0.360 Region-enriched R5: 1.284/0.00002 Regeneration-upregulated BL: 1.551 Regeneration-enriched BL: 1.551 |
KPNA2 | 1.678 | - | - | 0.712 | - | - | 0.966 | Mlig455_029420 {REF} {Length: 2476} {TRANSSPLICED} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=191.5]; Importin beta binding domain [PF01749.22, score=66.2]; HEAT-like repeat [PF13513.8, score=63.2]; Atypical Arm repeat [PF16186.7, score=62.2]; HEAT repeats [PF13646.8, score=51.2]; HEAT repeat [PF02985.24, score=34.0]} {Human: ENSG00000182481, KPNA2, karyopherin subunit alpha 2, [Score=458, Expect=4e-156]} {Mouse: ENSMUSG00000018362, Kpna2, karyopherin (importin) alpha 2, [Score=451, Expect=2e-153]; ENSMUSG00000066878, Gm10184, predicted pseudogene 10184, [Score=451, Expect=2e-153]; ENSMUSG00000027782, Kpna4, karyopherin (importin) alpha 4, [Score=431, Expect=1e-145]} {Dmel: FBgn0267727, Pen, Pendulin, [RH, Score=397, Expect=2e-132]} {Celegans: WBGene00002074, ima-3, Importin subunit alpha-3, [Score=376, Expect=1e-124]} {Smed: dd_Smed_v6_590_0_1, dd_Smed_v6_590_0_1, [Score=419, Expect=2e-141]} {RNA1509_1276} {RNA1310_8995.1, RNA1509_1276} {RNA1509_1276, RNA815_2897} |
4. | MligTC455_33269 | 864 | 18 | Mlig455_031609 | Neo: - Age: - Region-specific R4: 2.043 Region-enriched R4: 1.624/0.00001 |
TMEM161B | 1.667 | - | - | - | 0.708 | - | 0.959 | Mlig455_031609 {REF} {Length: 3778} {TRANSSPLICED} {Pfam: Predicted transmembrane protein 161AB [PF10268.11, score=309.8]} {Human: ENSG00000164180, TMEM161B, transmembrane protein 161B, [RH, Score=191, Expect=9e-55]} {Mouse: ENSMUSG00000035762, Tmem161b, transmembrane protein 161B, [RH, Score=208, Expect=3e-61]} {Dmel: FBgn0036133, CG7638, [RH, Score=184, Expect=2e-52]} {Celegans: WBGene00013601, Y87G2A.13, [RH, Score=65.5, Expect=3e-11]} {Smed: dd_Smed_v6_9540_0_1, dd_Smed_v6_9540_0_1, [RH, Score=218, Expect=1e-65]} {RNA1509_12155} {RNA1310_14152.1, RNA1509_12155} {RNA1509_12155, RNA815_5969} |
5. | MligTC455_07315 | 1412 | 29.41 | Mlig455_000426, Mlig455_024855 | Neo: - Age: - Region-enriched R5: 1.338/0.00399 |
SIN3A, SIN3B | 0.978 | - | - | - | - | - | 0.978 | Mlig455_000426 {REF} {Length: 2868} {Pfam: C-terminal domain of Sin3a protein [PF16879.7, score=98.6]} {Human: ENSG00000127511, SIN3B, SIN3 transcription regulator family member B, [Score=144, Expect=2e-35]; ENSG00000169375, SIN3A, SIN3 transcription regulator family member A, [Score=137, Expect=5e-33]} {Mouse: ENSMUSG00000031622, Sin3b, transcriptional regulator, SIN3B (yeast), [Score=160, Expect=2e-40]} {Dmel: FBgn0022764, Sin3A, [Score=108, Expect=4e-24]} {Smed: dd_Smed_v6_7034_0_1, dd_Smed_v6_7034_0_1, [Score=71.6, Expect=1e-12]} {RNA1509_4899} {RNA1310_3136.1} {RNA815_1997} Mlig455_024855 {REF} {Length: 6647} {Pfam: C-terminal domain of Sin3a protein [PF16879.7, score=79.7]; Bacterial protein of unknown function (DUF937) [PF06078.13, score=19.1]} {Human: ENSG00000169375, SIN3A, SIN3 transcription regulator family member A, [Score=110, Expect=3e-25]; ENSG00000127511, SIN3B, SIN3 transcription regulator family member B, [Score=107, Expect=4e-24]} {Mouse: ENSMUSG00000031622, Sin3b, transcriptional regulator, SIN3B (yeast), [Score=141, Expect=1e-35]} {Dmel: FBgn0022764, Sin3A, [Score=107, Expect=2e-24]} {Smed: dd_Smed_v6_7034_0_1, dd_Smed_v6_7034_0_1, [Score=67.8, Expect=6e-12]} {RNA1509_56147} {RNA1310_3136.1} {RNA815_14715} |
6. | MligTC455_07314 | 687 | 14.32 | Mlig455_000525 | Neo: Irradiation Age: - Region-enriched R5: 1.319/0.00385 |
SIN3B | 0.976 | - | - | - | - | - | 0.976 | Mlig455_000525 {REF} {Length: 4206} {TRANSSPLICED} {Pfam: C-terminal domain of Sin3a protein [PF16879.7, score=97.0]} {Human: ENSG00000127511, SIN3B, SIN3 transcription regulator family member B, [Score=186, Expect=1e-48]} {Mouse: ENSMUSG00000031622, Sin3b, transcriptional regulator, SIN3B (yeast), [Score=196, Expect=3e-52]} {Dmel: FBgn0022764, Sin3A, [Score=147, Expect=2e-36]} {Smed: dd_Smed_v6_7034_0_1, dd_Smed_v6_7034_0_1, [Score=97.4, Expect=9e-21]} {RNA1509_4899} {RNA1310_4266.2} {RNA815_1997} |
7. | MligTC455_39647 | 1875 | 39.07 | Mlig455_021993, Mlig455_022046 | Neo: - Age: logFC(26M/2M)=0.652 |
SF3A3 | 0.965 | - | - | - | - | - | 0.965 | Mlig455_021993 {REF} {Length: 1884} {TRANSSPLICED} {Pfam: SF3a60/Prp9 C-terminal [PF11931.10, score=183.7]; Replication stress response SDE2 C-terminal [PF13297.8, score=96.5]; Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 [PF16837.7, score=60.7]; Splicing factor SF3a60 binding domain [PF12108.10, score=28.6]} {Human: ENSG00000183431, SF3A3, splicing factor 3a subunit 3, [RH, Score=629, Expect=0.0]} {Mouse: ENSMUSG00000028902, Sf3a3, splicing factor 3a, subunit 3, [RH, Score=628, Expect=0.0]} {Dmel: FBgn0014366, noi, noisette, [RH, Score=609, Expect=0.0]} {Celegans: WBGene00011758, T13H5.4, [RH, Score=524, Expect=0.0]} {Smed: dd_Smed_v6_2653_0_1, dd_Smed_v6_2653_0_1, [RH, Score=551, Expect=0.0]} {RNA1509_27195} {RNA1310_12410} {RNA815_13038} Mlig455_022046 {REF} {Length: 1884} {TRANSSPLICED} {Pfam: SF3a60/Prp9 C-terminal [PF11931.10, score=183.7]; Replication stress response SDE2 C-terminal [PF13297.8, score=96.5]; Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 [PF16837.7, score=60.7]; Splicing factor SF3a60 binding domain [PF12108.10, score=28.6]} {Human: ENSG00000183431, SF3A3, splicing factor 3a subunit 3, [RH, Score=629, Expect=0.0]} {Mouse: ENSMUSG00000028902, Sf3a3, splicing factor 3a, subunit 3, [RH, Score=628, Expect=0.0]} {Dmel: FBgn0014366, noi, noisette, [RH, Score=609, Expect=0.0]} {Celegans: WBGene00011758, T13H5.4, [RH, Score=524, Expect=0.0]} {Smed: dd_Smed_v6_2653_0_1, dd_Smed_v6_2653_0_1, [RH, Score=551, Expect=0.0]} {RNA1509_26009, RNA1509_27195, RNA1509_35084, RNA1509_58691, RNA1509_9315} {RNA1310_12410, RNA1509_26009, RNA1509_27195, RNA1509_35084, RNA1509_58691, RNA1509_9315} {RNA1509_26009, RNA1509_27195, RNA1509_35084, RNA1509_58691, RNA1509_9315, RNA815_13038} |
8. | MligTC455_39646 | 934 | 19.46 | Mlig455_021914 | Neo: Neoblast, stringent |
SF3A3 | 0.964 | - | - | - | - | - | 0.964 | Mlig455_021914 {REF} {Length: 1804} {TRANSSPLICED} {Pfam: SF3a60/Prp9 C-terminal [PF11931.10, score=144.3]} {Human: ENSG00000183431, SF3A3, splicing factor 3a subunit 3, [Score=243, Expect=9e-77]} {Mouse: ENSMUSG00000028902, Sf3a3, splicing factor 3a, subunit 3, [Score=243, Expect=3e-77]} {Dmel: FBgn0014366, noi, noisette, [Score=253, Expect=9e-81]} {Celegans: WBGene00011758, T13H5.4, [Score=206, Expect=3e-63]} {Smed: dd_Smed_v6_2653_0_1, dd_Smed_v6_2653_0_1, [Score=207, Expect=3e-63]} {RNA1509_27195} {RNA1310_12410} {RNA815_13038} |
9. | MligTC455_30371 | 1006 | 20.96 | Mlig455_056792 | Neo: Int S/G2/M Age: - |
PPHLN1 | 0.953 | - | - | - | - | - | 0.953 | Mlig455_056792 {REF} {Length: 4639} {Pfam: Transcriptional regulatory protein LGE1 [PF11488.10, score=33.4]} {Human: ENSG00000134283, PPHLN1, periphilin 1, [RH, Score=82.8, Expect=1e-16]} {Mouse: ENSMUSG00000036167, Pphln1, periphilin 1, [RH, Score=80.9, Expect=2e-16]} {Celegans: WBGene00013307, Y57G11C.9, [Score=56.2, Expect=3e-08]} {Smed: dd_Smed_v6_3002_0_1, dd_Smed_v6_3002_0_1, [Score=112, Expect=7e-27]} {RNA1509_16220, RNA1509_16318, RNA1509_17626} {RNA1310_18930, RNA1509_16220, RNA1509_17626} {RNA1509_16220, RNA1509_17626, RNA815_5252.1} |
10. | MligTC455_50593 | 1562 | 32.54 | Mlig455_016015, Mlig455_059733 | Neo: Neoblast, stringent Age: - |
TK2 | 0.952 | - | - | - | - | - | 0.952 | Mlig455_016015 {REF} {Length: 1538} {TRANSSPLICED} {Pfam: Deoxynucleoside kinase [PF01712.21, score=57.7]} {Human: ENSG00000166548, TK2, thymidine kinase 2, mitochondrial, [Score=65.9, Expect=3e-13]} {Mouse: ENSMUSG00000014554, Dguok, deoxyguanosine kinase, [Score=62.0, Expect=4e-12]; ENSMUSG00000029366, Dck, deoxycytidine kinase, [Score=59.7, Expect=3e-11]} {Dmel: FBgn0022338, dnk, deoxyribonucleoside kinase, [Score=70.9, Expect=1e-15]} {RNA1509_10988} {RNA1310_30595.1} {RNA815_13849} Mlig455_059733 {REF} {Length: 1097} {TRANSSPLICED} {Pfam: Deoxynucleoside kinase [PF01712.21, score=167.9]; AAA domain [PF13238.8, score=31.5]; AAA domain [PF13671.8, score=24.2]} {Human: ENSG00000166548, TK2, thymidine kinase 2, mitochondrial, [Score=166, Expect=1e-49]} {Mouse: ENSMUSG00000035824, Tk2, thymidine kinase 2, mitochondrial, [Score=162, Expect=1e-48]} {Dmel: FBgn0022338, dnk, deoxyribonucleoside kinase, [Score=167, Expect=3e-51]} {RNA1509_10988} {RNA1310_30595.1} {RNA815_13849} |