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Results for MligTC455_49457

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_49457 1225 25.52 Mlig455_005617, Mlig455_014432, Mlig455_070181

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.375

Mlig455_005617 {REF} {Length: 1304} {RNA1509_48463} {RNA1310_46663, RNA1509_48463} {RNA1509_48463, RNA815_4404.1}

Mlig455_014432 {REF} {Length: 1338} {RNA1509_48463} {RNA1310_46663} {RNA815_4404.1}

Mlig455_070181 {REF} {Length: 1176} {RNA1509_47545, RNA1509_48463} {RNA1310_46663, RNA1509_47545} {RNA1509_47545, RNA815_4404.1}

Cumulative graph for MligTC455_49457

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -7.425 4.931 0.01845 0.37862
RegionR2 1.943 4.931 0.00805 0.08752
RegionR3 0.85 4.931 0.30012 0.84235
RegionR4 0.657 4.931 0.48751 0.81484
RegionR5 -0.418 4.931 0.94385 1.00000
RegionR6 0.844 4.931 0.30947 0.89945
RegionR7 1.758 4.931 0.01121 0.18435
RegionR8 1.792 4.931 0.02414 0.30344

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.691 4.931 0.99995 1.00000
RegenerationR2 0.23 4.931 0.64406 0.93323
RegenerationR3 0.054 4.931 0.92522 1.00000
RegenerationR4 0.228 4.931 0.69939 0.95337
RegenerationR5 0.234 4.931 0.66868 0.94043
RegenerationR6 -0.102 4.931 0.84858 0.99996
RegenerationBL 0.127 4.931 0.80321 1.00000
RegenerationTP -0.692 4.931 0.22475 0.66911


Genes with expression patterns similar to MligTC455_49457

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_49457 1225 25.52 Mlig455_005617, Mlig455_014432, Mlig455_070181

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.375

6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_005617 {REF} {Length: 1304} {RNA1509_48463} {RNA1310_46663, RNA1509_48463} {RNA1509_48463, RNA815_4404.1}

Mlig455_014432 {REF} {Length: 1338} {RNA1509_48463} {RNA1310_46663} {RNA815_4404.1}

Mlig455_070181 {REF} {Length: 1176} {RNA1509_47545, RNA1509_48463} {RNA1310_46663, RNA1509_47545} {RNA1509_47545, RNA815_4404.1}
2. MligTC455_52874 382 7.96 Mlig455_026014, Mlig455_070442

Neo: -

Age: -

CDH23 4.458 0.858 0.866 - 0.926 0.842 0.966

Mlig455_026014 {REF} {Length: 10931} {TRANSSPLICED} {Pfam: Cadherin domain [PF00028.19, score=362.8]; Cadherin-like [PF16184.7, score=40.0]; Cadherin-like [PF08266.14, score=32.1]} {Human: ENSG00000107736, CDH23, cadherin related 23, [Score=327, Expect=4e-90]} {Mouse: ENSMUSG00000012819, Cdh23, cadherin 23 (otocadherin), [Score=327, Expect=2e-90]} {Dmel: FBgn0038247, Cad88C, Cadherin 88C, [Score=404, Expect=8e-116]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=211, Expect=1e-54]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [Score=498, Expect=9e-149]} {RNA1509_48951} {RNA1310_475.1} {RNA815_321.1}

Mlig455_070442 {REF} {Length: 10801} {TRANSSPLICED} {Pfam: Cadherin domain [PF00028.19, score=364.1]; Cadherin-like [PF16184.7, score=39.7]; Cadherin-like [PF08266.14, score=30.9]} {Human: ENSG00000107736, CDH23, cadherin related 23, [Score=323, Expect=4e-89]} {Mouse: ENSMUSG00000012819, Cdh23, cadherin 23 (otocadherin), [Score=326, Expect=4e-90]} {Dmel: FBgn0038247, Cad88C, Cadherin 88C, [Score=404, Expect=8e-116]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=211, Expect=1e-54]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [Score=495, Expect=1e-147]} {RNA1509_44393, RNA1509_48951} {RNA1310_475.1, RNA1509_44393} {RNA1509_44393, RNA815_321.1}
3. MligTC455_53843 1448 30.17 Mlig455_048664

Neo: -

Age: logFC(26M/2M)=0.488

4.388 0.824 0.915 - 0.910 0.776 0.963 Mlig455_048664 {REF} {Length: 1660} {RNA1509_15580} {RNA1310_24090, RNA1509_15580} {RNA1509_15580, RNA815_10676.2}
4. MligTC455_18920 299 6.22 Mlig455_052039

Neo: -

Age: Down-Up-Down

Region-enriched R8: 3.175/0.01587

RTN4R 4.132 - 0.877 0.753 0.837 0.706 0.959 Mlig455_052039 {REF} {Length: 1911} {Pfam: Leucine rich repeat [PF13855.8, score=113.0]; Leucine Rich repeats (2 copies) [PF12799.9, score=46.5]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=24.5]} {Human: ENSG00000040608, RTN4R, reticulon 4 receptor, [Score=73.2, Expect=2e-13]} {Mouse: ENSMUSG00000111113, Rtn4r, reticulon 4 receptor, [Score=72.8, Expect=2e-13]; ENSMUSG00000043811, Rtn4r, reticulon 4 receptor, [Score=72.8, Expect=2e-13]} {Dmel: FBgn0004364, 18w, 18 wheeler, [Score=71.2, Expect=7e-13]} {Celegans: WBGene00001443, fli-1, Protein flightless-1 homolog, [Score=56.6, Expect=2e-08]} {Smed: dd_Smed_v6_12111_0_1, dd_Smed_v6_12111_0_1, [Score=48.1, Expect=8e-06]} {RNA1310_19257.1} {RNA815_9099}
5. MligTC455_27650 178 3.72 Mlig455_017720

Neo: -

Age: logFC(26M/2M)=-0.928

Region-enriched R2: 3.586/0.00082

ADAM33 4.095 0.746 - 0.765 0.766 0.857 0.961 Mlig455_017720 {REF} {Length: 4499} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=124.3]; Disintegrin [PF00200.25, score=66.8]; Metallo-peptidase family M12 [PF13688.8, score=62.2]; ADAM cysteine-rich [PF08516.14, score=61.3]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=33.1]} {Human: ENSG00000149451, ADAM33, ADAM metallopeptidase domain 33, [Score=237, Expect=1e-64]; ENSG00000151651, ADAM8, ADAM metallopeptidase domain 8, [Score=233, Expect=2e-63]; ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [Score=230, Expect=2e-62]; ENSG00000148848, ADAM12, ADAM metallopeptidase domain 12, [Score=228, Expect=4e-61]; ENSG00000069206, ADAM7, ADAM metallopeptidase domain 7, [Score=226, Expect=4e-61]; ENSG00000042980, ADAM28, ADAM metallopeptidase domain 28, [Score=226, Expect=4e-61]} {Mouse: ENSMUSG00000079058, Adam34, a disintegrin and metallopeptidase domain 34, [RH, Score=248, Expect=4e-69]; ENSMUSG00000050190, Gm5346, predicted gene 5346, [RH, Score=239, Expect=3e-66]} {Dmel: FBgn0265140, Meltrin, [RH, Score=288, Expect=1e-79]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=246, Expect=3e-67]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=225, Expect=3e-60]} {RNA1509_7654} {RNA1310_9319.1} {RNA815_4173.1}
6. MligTC455_26615 572 11.92 Mlig455_045072

Neo: -

Age: logFC(26M/2M)=-0.522

4.004 - 0.862 0.777 0.703 0.951 0.711 Mlig455_045072 {REF} {Length: 1124} {RNA1509_43319} {RNA1310_55165, RNA1509_43319} {RNA1509_43319, RNA815_27927}
7. MligTC455_47669 793 16.52 Mlig455_040755

Neo: -

Age: -

Region-enriched R2: 1.568/0.00407

3.692 - - 0.893 0.943 0.894 0.962 Mlig455_040755 {REF} {Length: 8844} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=33.0]; Ankyrin repeats (many copies) [PF13637.8, score=21.8]} {RNA1509_15853} {RNA1310_18916} {RNA815_34185}
8. MligTC455_47670 709 14.77 Mlig455_064585

Neo: -

Age: -

Region-enriched R2: 1.616/0.00648

3.673 - - 0.880 0.964 0.857 0.972 Mlig455_064585 {REF} {Length: 1016} {RNA1509_15853} {RNA1310_37053} {RNA815_24569.1}
9. MligTC455_47412 245 5.11 Mlig455_025659

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-1.406

RTL1 3.557 - - 0.907 0.771 0.917 0.962 Mlig455_025659 {REF} {Length: 3817} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=105.5]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=100.5]; Integrase zinc binding domain [PF17921.3, score=62.6]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=62.3]; Integrase core domain [PF00665.28, score=43.8]; Zinc knuckle [PF00098.25, score=21.5]} {Human: ENSG00000254656, RTL1, retrotransposon Gag like 1, [Score=91.7, Expect=6e-18]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=63.9, Expect=1e-09]} {Smed: dd_Smed_v6_6563_0_1, dd_Smed_v6_6563_0_1, [Score=291, Expect=3e-82]} {RNA1509_33291} {RNA1310_923.1} {RNA815_1595}
10. MligTC455_30298 374 7.79 Mlig455_043411, Mlig455_043553

Neo: -

Age: -

3.538 - - 0.887 0.892 0.799 0.960

Mlig455_043411 {REF} {Length: 5334} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF13424.8, score=68.9]; Tetratricopeptide repeat [PF13181.8, score=29.2]; AAA ATPase domain [PF13191.8, score=26.2]; Tetratricopeptide repeat [PF07719.19, score=26.0]; Tetratricopeptide repeat [PF14559.8, score=25.5]; Tetratricopeptide repeat [PF00515.30, score=24.6]; NACHT domain [PF05729.14, score=23.4]; Tetratricopeptide repeat [PF13374.8, score=21.8]} {Mouse: ENSMUSG00000044937, Ttc41, tetratricopeptide repeat domain 41, [Score=133, Expect=1e-30]} {Smed: dd_Smed_v6_12326_0_4, dd_Smed_v6_12326_0_4, [Score=203, Expect=9e-53]} {RNA1509_11012} {RNA1310_2964, RNA1509_11012} {RNA1509_11012, RNA815_1508.1}

Mlig455_043553 {REF} {Length: 5340} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF13424.8, score=68.0]; Tetratricopeptide repeat [PF13181.8, score=28.2]; AAA ATPase domain [PF13191.8, score=26.2]; Tetratricopeptide repeat [PF00515.30, score=25.3]; Tetratricopeptide repeat [PF14559.8, score=25.2]; Tetratricopeptide repeat [PF07719.19, score=24.6]; NACHT domain [PF05729.14, score=23.0]; Tetratricopeptide repeat [PF13374.8, score=21.0]; Zeta toxin [PF06414.14, score=20.0]} {Mouse: ENSMUSG00000044937, Ttc41, tetratricopeptide repeat domain 41, [RH, Score=187, Expect=1e-47]} {Smed: dd_Smed_v6_12326_0_3, dd_Smed_v6_12326_0_3, [RH, Score=218, Expect=3e-57]} {RNA1509_11012} {RNA1310_2964} {RNA815_1508.1}
11. MligTC455_30297 190 3.95 Mlig455_043386

Neo: -

Age: -

3.533 - - 0.885 0.895 0.797 0.956 Mlig455_043386 {REF} {Length: 3325} {Pfam: Tetratricopeptide repeat [PF13424.8, score=72.0]; Tetratricopeptide repeat [PF13181.8, score=32.7]; Tetratricopeptide repeat [PF07719.19, score=29.8]; Tetratricopeptide repeat [PF00515.30, score=29.6]; Tetratricopeptide repeat [PF14559.8, score=27.0]; Tetratricopeptide repeat [PF13374.8, score=24.9]; Tetratricopeptide repeat [PF13428.8, score=20.2]; Tetratricopeptide repeat [PF13432.8, score=19.8]} {Smed: dd_Smed_v6_12326_0_3, dd_Smed_v6_12326_0_3, [Score=87.0, Expect=3e-17]} {RNA1509_11012} {RNA1310_2964} {RNA815_1508.1}
12. MligTC455_22713 787 16.4 Mlig455_023280

Neo: -

Age: -

3.488 - - 0.730 0.904 0.952 0.902 Mlig455_023280 {REF} {Length: 2898} {RNA1509_17376} {RNA1310_6954} {RNA815_8376.1}
13. MligTC455_29204 333 6.93 Mlig455_052247

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.586

ANK3 3.487 - - 0.843 0.828 0.848 0.968 Mlig455_052247 {REF} {Length: 5485} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=62.8]; Ankyrin repeats (many copies) [PF13637.8, score=51.6]; Ankyrin repeat [PF00023.32, score=40.1]; Ankyrin repeat [PF13606.8, score=38.1]; Ankyrin repeats (many copies) [PF13857.8, score=34.4]; Mab-21 protein [PF03281.16, score=20.6]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=65.9, Expect=3e-10]} {Mouse: ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=65.9, Expect=2e-10]} {Dmel: FBgn0031473, CG3104, [Score=74.3, Expect=6e-14]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=58.2, Expect=2e-08]} {Smed: dd_Smed_v6_9936_0_1, dd_Smed_v6_9936_0_1, [Score=70.5, Expect=2e-12]} {RNA1509_39688} {RNA1310_6142.1} {RNA815_6750.1}
14. MligTC455_14903 1751 36.49 Mlig455_037514

Neo: -

Age: -

Region-enriched R8: 1.893/0.00470

3.485 - 0.870 - 0.779 0.861 0.975 Mlig455_037514 {REF} {Length: 2886} {Dmel: FBgn0034294, Muc55B, Mucin 55B, [Score=58.5, Expect=6e-09]} {Celegans: WBGene00008194, C49C3.4, [Score=51.2, Expect=1e-06]} {RNA1509_4337} {RNA1310_7259} {RNA815_206}
15. MligTC455_29203 334 6.95 Mlig455_037140

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.614

3.464 - - 0.846 0.797 0.857 0.964 Mlig455_037140 {REF} {Length: 5032} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=37.3]; Ankyrin repeat [PF00023.32, score=28.8]; Ankyrin repeat [PF13606.8, score=25.8]; Ankyrin repeats (many copies) [PF13637.8, score=24.6]; Ankyrin repeats (many copies) [PF13857.8, score=22.2]; Mab-21 protein [PF03281.16, score=20.5]} {RNA1509_39416} {RNA1310_14401} {RNA815_5545.1}
16. MligTC455_16641 1524 31.75 Mlig455_043685, Mlig455_043752, Mlig455_047473

Neo: -

Age: Down-Up-Up

Region-enriched R8: 2.371/0.00579

3.39 - 0.951 0.736 - 0.883 0.820

Mlig455_043685 {REF} {Length: 1558} {Pfam: Domain of unknown function (DUF4735) [PF15882.7, score=104.2]} {Smed: dd_Smed_v6_13989_0_1, dd_Smed_v6_13989_0_1, [Score=60.1, Expect=6e-10]} {RNA1509_51030} {RNA1310_23381} {RNA815_11328}

Mlig455_043752 {REF} {Length: 1659} {Pfam: Domain of unknown function (DUF4735) [PF15882.7, score=104.5]} {Smed: dd_Smed_v6_13989_0_1, dd_Smed_v6_13989_0_1, [Score=59.3, Expect=1e-09]} {RNA1509_51030} {RNA1310_23381} {RNA815_11328}

Mlig455_047473 {REF} {Length: 1659} {Pfam: Domain of unknown function (DUF4735) [PF15882.7, score=104.5]} {Smed: dd_Smed_v6_13989_0_1, dd_Smed_v6_13989_0_1, [Score=59.3, Expect=1e-09]} {RNA1509_18230, RNA1509_43643, RNA1509_51030} {RNA1310_23381, RNA1509_18230, RNA1509_43643, RNA1509_51030} {RNA1509_18230, RNA1509_43643, RNA1509_51030, RNA815_11328}
17. MligTC455_41595 483 10.07 Mlig455_065096

Neo: -

Age: -

3.362 - - 0.798 0.752 0.833 0.979 Mlig455_065096 {REF} {Length: 1103} {RNA1310_35732} {RNA815_16408}
18. MligTC455_14181 1196 24.91 Mlig455_043723, Mlig455_047435

Neo: -

Age: logFC(26M/2M)=-0.334

3.358 - 0.824 - 0.825 0.732 0.977

Mlig455_043723 {REF} {Length: 1333} {RNA1509_15671} {RNA1310_24777} {RNA815_10623}

Mlig455_047435 {REF} {Length: 1668} {RNA1509_15671} {RNA1310_24777, RNA1509_15671} {RNA1509_15671, RNA815_10623}
19. MligTC455_20142 488 10.17 Mlig455_036513

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=-0.225

3.351 - 0.877 - 0.772 0.738 0.964 Mlig455_036513 {REF} {Length: 1074} {NoTransDecoderORF} {RNA1509_4350} {RNA1310_20554, RNA1509_4350} {RNA1509_4350, RNA815_8810.1}
20. MligTC455_31998 283 5.91 Mlig455_067851

Neo: -

Age: -

3.341 - 0.774 - 0.735 0.876 0.956 Mlig455_067851 {REF} {Length: 2274} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=56.5]} {Smed: dd_Smed_v6_7249_0_1, dd_Smed_v6_7249_0_1, [Score=142, Expect=6e-39]} {RNA1509_24876, RNA1509_54205} {RNA1310_15051, RNA1509_24876, RNA1509_54205} {RNA1509_24876, RNA1509_54205, RNA815_26796}
21. MligTC455_22150 189 3.94 Mlig455_054947

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=2.071

XDH 3.335 - - 0.723 0.810 0.829 0.973 Mlig455_054947 {REF} {Length: 5481} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=346.4]; [2Fe-2S] binding domain [PF01799.22, score=95.7]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=91.5]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=51.5]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=47.3]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=25.1]} {Human: ENSG00000158125, XDH, xanthine dehydrogenase, [Score=476, Expect=9e-146]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=471, Expect=4e-144]; ENSMUSG00000079554, Aox2, aldehyde oxidase 2, [Score=457, Expect=7e-139]; ENSMUSG00000063558, Aox1, aldehyde oxidase 1, [Score=456, Expect=1e-138]; ENSMUSG00000038242, Aox4, aldehyde oxidase 4, [Score=449, Expect=5e-136]} {Dmel: FBgn0267408, AOX1, Aldehyde oxidase 1, [Score=640, Expect=0.0]} {Celegans: WBGene00010083, xhd-1, [Score=485, Expect=1e-149]} {RNA1509_325, RNA1509_38160} {RNA1310_1603.1, RNA1509_38160} {RNA1509_38160, RNA815_224.2}
22. MligTC455_47329 793 16.52 Mlig455_025847, Mlig455_025942

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.434

DSTYK 3.318 - - 0.789 0.797 0.952 0.780

Mlig455_025847 {REF} {Length: 4190} {Pfam: Protein kinase domain [PF00069.27, score=136.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=120.6]; Dynamin family [PF00350.25, score=73.6]; 50S ribosome-binding GTPase [PF01926.25, score=31.7]; Elongation factor Tu GTP binding domain [PF00009.29, score=26.7]; Gtr1/RagA G protein conserved region [PF04670.14, score=19.7]} {Human: ENSG00000133059, DSTYK, dual serine/threonine and tyrosine protein kinase, [Score=179, Expect=1e-45]} {Mouse: ENSMUSG00000042046, Dstyk, dual serine/threonine and tyrosine protein kinase, [Score=193, Expect=2e-50]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=95.9, Expect=5e-20]} {Celegans: WBGene00013643, Y105C5A.24, [Score=100, Expect=9e-22]} {Smed: dd_Smed_v6_1371_0_1, dd_Smed_v6_1371_0_1, [RH, Score=401, Expect=6e-125]} {RNA1509_27256, RNA1509_31736} {RNA1310_3463.1, RNA1509_27256} {RNA1509_27256, RNA815_1104.1}

Mlig455_025942 {REF} {Length: 4065} {Pfam: Protein kinase domain [PF00069.27, score=135.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=121.1]; Dynamin family [PF00350.25, score=73.6]; 50S ribosome-binding GTPase [PF01926.25, score=31.7]; Elongation factor Tu GTP binding domain [PF00009.29, score=28.6]; Gtr1/RagA G protein conserved region [PF04670.14, score=19.5]} {Human: ENSG00000133059, DSTYK, dual serine/threonine and tyrosine protein kinase, [Score=181, Expect=2e-46]} {Mouse: ENSMUSG00000042046, Dstyk, dual serine/threonine and tyrosine protein kinase, [Score=195, Expect=3e-51]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=97.8, Expect=1e-20]} {Celegans: WBGene00013643, Y105C5A.24, [Score=99.8, Expect=1e-21]} {Smed: dd_Smed_v6_1371_0_1, dd_Smed_v6_1371_0_1, [RH, Score=397, Expect=2e-123]} {RNA1509_31736} {RNA1310_3463.1} {RNA815_1104.1}
23. MligTC455_44042 460 9.59 Mlig455_021815

Neo: -

Age: logFC(26M/2M)=-0.341

CCDC181 3.311 - - 0.708 0.774 0.879 0.950 Mlig455_021815 {REF} {Length: 2436} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4207) [PF13904.8, score=29.1]} {Human: ENSG00000117477, CCDC181, coiled-coil domain containing 181, [Score=70.5, Expect=2e-12]} {Mouse: ENSMUSG00000026578, Ccdc181, coiled-coil domain containing 181, [Score=72.0, Expect=4e-13]} {Smed: dd_Smed_v6_8117_0_1, dd_Smed_v6_8117_0_1, [Score=76.6, Expect=6e-15]} {RNA1509_20789} {RNA1310_10957.1, RNA1509_20789} {RNA1509_20789, RNA815_9557}
24. MligTC455_24615 803 16.72 Mlig455_027166

Neo: -

Age: logFC(26M/2M)=-0.507

ECT2 3.306 - 0.717 - 0.873 0.756 0.960 Mlig455_027166 {REF} {Length: 2510} {Pfam: RhoGEF domain [PF00621.22, score=124.0]; Winged helix-turn helix [PF13592.8, score=20.5]} {Human: ENSG00000114346, ECT2, epithelial cell transforming 2, [Score=80.9, Expect=2e-15]} {Mouse: ENSMUSG00000020640, Itsn2, intersectin 2, [Score=79.7, Expect=5e-15]; ENSMUSG00000027699, Ect2, ect2 oncogene, [Score=77.0, Expect=3e-14]} {Dmel: FBgn0003041, pbl, pebble, [Score=56.6, Expect=5e-08]} {Celegans: WBGene00002297, ect-2, ECT2 (Mammalian Rho GEF) homolog, [Score=69.7, Expect=3e-12]} {Smed: dd_Smed_v6_2922_0_1, dd_Smed_v6_2922_0_1, [Score=50.1, Expect=3e-06]} {RNA1509_21158} {RNA1310_6370} {RNA815_1845}
25. MligTC455_47244 216 4.49 Mlig455_016130

Neo: -

Age: -

Region-enriched R2: 3.391/0.02151
Region-enriched R6: 2.922/0.03099

3.304 0.702 - 0.954 0.743 0.905 - Mlig455_016130 {REF} {Length: 3312} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=27.9]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=20.5]} {Smed: dd_Smed_v6_24733_0_1, dd_Smed_v6_24733_0_1, [RH, Score=231, Expect=1e-71]} {RNA1509_41111} {RNA1310_18481.1} {RNA815_10445}
26. MligTC455_32445 285 5.93 Mlig455_041727, Mlig455_042282

Neo: -

Age: -

ANK2 3.302 0.710 0.867 - 0.761 - 0.964

Mlig455_041727 {REF} {Length: 4931} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=276.7]; Ankyrin repeats (many copies) [PF13637.8, score=238.3]; Ankyrin repeat [PF00023.32, score=223.0]; Ankyrin repeats (many copies) [PF13857.8, score=214.9]; Ankyrin repeat [PF13606.8, score=201.4]; Ion transport protein [PF00520.33, score=46.6]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=211, Expect=1e-54]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=290, Expect=2e-80]} {Dmel: FBgn0011747, Ank, Ankyrin, [Score=210, Expect=2e-54]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=489, Expect=7e-151]} {Smed: dd_Smed_v6_6201_0_2, dd_Smed_v6_6201_0_2, [RH, Score=745, Expect=0.0]} {RNA1509_18945} {RNA1310_1506.1, RNA1509_18945} {RNA1509_18945, RNA815_450.1}

Mlig455_042282 {REF} {Length: 4940} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=273.8]; Ankyrin repeats (many copies) [PF13637.8, score=232.4]; Ankyrin repeat [PF00023.32, score=218.4]; Ankyrin repeats (many copies) [PF13857.8, score=210.6]; Ankyrin repeat [PF13606.8, score=197.5]; Ion transport protein [PF00520.33, score=46.6]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=214, Expect=2e-55]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=204, Expect=1e-52]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=201, Expect=2e-51]} {Dmel: FBgn0011747, Ank, Ankyrin, [Score=205, Expect=6e-53]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=487, Expect=5e-150]} {Smed: dd_Smed_v6_6201_0_2, dd_Smed_v6_6201_0_2, [RH, Score=736, Expect=0.0]} {RNA1509_18945} {RNA1310_1506.1} {RNA815_8298}
27. MligTC455_21353 452 9.41 Mlig455_004209, Mlig455_004221

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.406

3.301 - - 0.728 0.805 0.809 0.959

Mlig455_004209 {REF} {Length: 1786} {Smed: dd_Smed_v6_11196_0_1, dd_Smed_v6_11196_0_1, [RH, Score=100, Expect=1e-24]} {RNA1509_45598} {RNA1310_22701, RNA1509_45598} {RNA1509_45598, RNA815_19949}

Mlig455_004221 {REF} {Length: 1440} {Smed: dd_Smed_v6_11196_0_1, dd_Smed_v6_11196_0_1, [Score=84.0, Expect=9e-19]} {RNA1509_45598} {RNA1310_32084} {RNA815_19949}
28. MligTC455_52586 230 4.78 Mlig455_069158

Neo: -

Age: -

3.299 - - 0.787 0.734 0.818 0.960 Mlig455_069158 {REF} {Length: 3154} {RNA1509_45748, RNA1509_55217} {RNA1310_4688.1, RNA1509_45748} {RNA1509_45748, RNA815_38425}
29. MligTC455_43947 417 8.7 Mlig455_000958

Neo: -

Age: -

C11orf49 3.251 - 0.797 - 0.955 0.792 0.707 Mlig455_000958 {REF} {Length: 2098} {TRANSSPLICED} {Human: ENSG00000149179, C11orf49, chromosome 11 open reading frame 49, [RH, Score=155, Expect=4e-43]} {Mouse: ENSMUSG00000040591, 1110051M20Rik, RIKEN cDNA 1110051M20 gene, [RH, Score=152, Expect=2e-42]} {Smed: dd_Smed_v6_15877_0_1, dd_Smed_v6_15877_0_1, [RH, Score=81.3, Expect=7e-17]} {RNA1509_18525} {RNA1310_27928.1} {RNA815_15036.1}
30. MligTC455_25313 529 11.03 Mlig455_047806, Mlig455_047883

Neo: -

Age: Up-Down-Down

PCLO 3.243 0.798 - 0.716 - 0.761 0.968

Mlig455_047806 {REF} {Length: 4640} {Pfam: C2 domain [PF00168.32, score=102.8]; PDZ domain [PF17820.3, score=23.7]} {Human: ENSG00000186472, PCLO, piccolo presynaptic cytomatrix protein, [Score=115, Expect=2e-25]} {Mouse: ENSMUSG00000061601, Pclo, piccolo (presynaptic cytomatrix protein), [RH, Score=117, Expect=4e-26]} {Dmel: FBgn0003091, Pkc53E, Protein C kinase 53E, [Score=83.2, Expect=4e-16]} {Celegans: WBGene00004033, pkc-2, Protein kinase C-like 2, [Score=79.0, Expect=7e-15]} {Smed: dd_Smed_v6_9615_0_2, dd_Smed_v6_9615_0_2, [RH, Score=198, Expect=2e-52]} {RNA1509_12877} {RNA1310_21392} {RNA815_8186}

Mlig455_047883 {REF} {Length: 3110} {Smed: dd_Smed_v6_9615_0_2, dd_Smed_v6_9615_0_2, [RH, Score=192, Expect=2e-55]} {RNA1509_12877} {RNA1310_21392} {RNA815_8186}
31. MligTC455_17412 44 0.91 Mlig455_069737

Neo: -

Age: -

Region-enriched R2: 5.062/0.00923

3.235 - - 0.704 0.702 0.872 0.957 Mlig455_069737 {REF} {Length: 1628} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=42.8]} {Smed: dd_Smed_v6_31564_0_1, dd_Smed_v6_31564_0_1, [Score=72.8, Expect=3e-14]} {RNA1310_45758} {RNA815_42912}
32. MligTC455_49143 772 16.08 Mlig455_021704

Neo: -

Age: -

Region-enriched R2: 1.427/0.03420

3.219 - - 0.711 0.958 0.781 0.769 Mlig455_021704 {REF} {Length: 2489} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4537) [PF15057.8, score=48.8]} {Smed: dd_Smed_v6_13233_0_2, dd_Smed_v6_13233_0_2, [Score=60.1, Expect=4e-09]} {RNA1509_11962} {RNA1310_8951.1, RNA1509_11962}
33. MligTC455_18602 116 2.42 Mlig455_003494

Neo: -

Age: -

KCTD21 3.189 0.745 - 0.706 0.783 - 0.955 Mlig455_003494 {REF} {Length: 3275} {Pfam: BTB/POZ domain [PF02214.24, score=65.0]} {Human: ENSG00000188997, KCTD21, potassium channel tetramerization domain containing 21, [Score=88.6, Expect=3e-21]; ENSG00000183783, KCTD8, potassium channel tetramerization domain containing 8, [Score=87.8, Expect=7e-19]} {Mouse: ENSMUSG00000044952, Kctd21, potassium channel tetramerisation domain containing 21, [Score=87.8, Expect=5e-20]; ENSMUSG00000037653, Kctd8, potassium channel tetramerisation domain containing 8, [Score=85.9, Expect=2e-18]} {Dmel: FBgn0038839, Ktl, Kctd12-like, [Score=82.0, Expect=3e-18]} {Celegans: WBGene00014848, VM106R.1, [Score=77.4, Expect=4e-16]} {Smed: dd_Smed_v6_8654_0_1, dd_Smed_v6_8654_0_1, [Score=89.0, Expect=8e-21]} {RNA1310_21779.1} {RNA815_18356}
34. MligTC455_29012 227 4.74 Mlig455_004572

Neo: -

Age: Down-Down-Up

TMEM30A 3.187 - - 0.724 0.730 0.768 0.965 Mlig455_004572 {REF} {Length: 3160} {TRANSSPLICED} {Pfam: LEM3 (ligand-effect modulator 3) family / CDC50 family [PF03381.17, score=265.5]} {Human: ENSG00000112697, TMEM30A, transmembrane protein 30A, [RH, Score=234, Expect=7e-73]} {Mouse: ENSMUSG00000032328, Tmem30a, transmembrane protein 30A, [RH, Score=241, Expect=7e-76]} {Dmel: FBgn0030752, CG9947, [RH, Score=294, Expect=9e-97]} {Celegans: WBGene00019946, chat-1, CDC50 family protein chat-1, [Score=246, Expect=3e-78]} {Smed: dd_Smed_v6_6430_0_1, dd_Smed_v6_6430_0_1, [Score=275, Expect=2e-89]} {RNA1509_38539} {RNA1310_9371} {RNA815_12157}
35. MligTC455_48522 94 1.96 Mlig455_032491

Neo: -

Age: -

Region-enriched R2: 4.888/0.01251

3.174 0.749 - 0.775 - 0.700 0.950 Mlig455_032491 {REF} {Length: 2169} {Pfam: Sodium / potassium ATPase beta chain [PF00287.20, score=47.3]} {Dmel: FBgn0015776, nrv1, nervana 1, [Score=55.5, Expect=2e-08]} {RNA1310_12303} {RNA815_10417}
36. MligTC455_35019 168 3.49 Mlig455_046994

Neo: -

Age: -

ASIC4 3.172 0.775 - - 0.738 0.706 0.953 Mlig455_046994 {REF} {Length: 4001} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=101.4]} {Human: ENSG00000072182, ASIC4, acid sensing ion channel subunit family member 4, [Score=76.3, Expect=1e-13]} {Mouse: ENSMUSG00000033007, Asic4, acid-sensing (proton-gated) ion channel family member 4, [Score=76.3, Expect=8e-14]; ENSMUSG00000023017, Asic1, acid-sensing (proton-gated) ion channel 1, [Score=72.8, Expect=8e-13]} {Smed: dd_Smed_v6_15233_0_1, dd_Smed_v6_15233_0_1, [RH, Score=103, Expect=1e-22]} {RNA1509_33816} {RNA1310_3176, RNA1509_33816} {RNA1509_33816, RNA815_12439}
37. MligTC455_52120 179 3.73 Mlig455_024423, Mlig455_024577

Neo: -

Age: Down-Up-Down

Region-enriched R2: 4.068/0.01755

POU4F3 3.167 0.755 - 0.702 0.747 - 0.963

Mlig455_024423 {REF} {Length: 1288} {TRANSSPLICED} {Pfam: Pou domain - N-terminal to homeobox domain [PF00157.19, score=104.8]; Homeodomain [PF00046.31, score=60.9]} {Human: ENSG00000091010, POU4F3, POU class 4 homeobox 3, [Score=212, Expect=1e-65]; ENSG00000152192, POU4F1, POU class 4 homeobox 1, [Score=211, Expect=2e-64]} {Mouse: ENSMUSG00000024497, Pou4f3, POU domain, class 4, transcription factor 3, [Score=212, Expect=7e-66]; ENSMUSG00000048349, Pou4f1, POU domain, class 4, transcription factor 1, [Score=211, Expect=2e-64]} {Dmel: FBgn0000028, acj6, abnormal chemosensory jump 6, [Score=209, Expect=2e-64]} {Celegans: WBGene00006818, unc-86, Transcription factor unc-86, [Score=188, Expect=4e-57]} {Smed: dd_Smed_v6_30562_0_1, dd_Smed_v6_30562_0_1, [Score=208, Expect=2e-64]} {RNA1509_57422} {RNA1310_23131} {RNA815_34447}

Mlig455_024577 {REF} {Length: 1325} {TRANSSPLICED} {Pfam: Pou domain - N-terminal to homeobox domain [PF00157.19, score=104.8]; Homeodomain [PF00046.31, score=60.9]} {Human: ENSG00000091010, POU4F3, POU class 4 homeobox 3, [Score=212, Expect=1e-65]; ENSG00000152192, POU4F1, POU class 4 homeobox 1, [Score=211, Expect=2e-64]} {Mouse: ENSMUSG00000024497, Pou4f3, POU domain, class 4, transcription factor 3, [Score=212, Expect=7e-66]; ENSMUSG00000048349, Pou4f1, POU domain, class 4, transcription factor 1, [Score=211, Expect=2e-64]} {Dmel: FBgn0000028, acj6, abnormal chemosensory jump 6, [Score=209, Expect=2e-64]} {Celegans: WBGene00006818, unc-86, Transcription factor unc-86, [Score=188, Expect=4e-57]} {Smed: dd_Smed_v6_30562_0_1, dd_Smed_v6_30562_0_1, [Score=208, Expect=2e-64]} {RNA1509_57422} {RNA1310_23131} {RNA815_34447}
38. MligTC455_19775 36 0.74 Mlig455_060359

Neo: -

Age: -

FCN1 3.119 0.733 - 0.732 0.702 - 0.952 Mlig455_060359 {REF} {Length: 1109} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=120.9]} {Human: ENSG00000085265, FCN1, ficolin 1, [Score=99.0, Expect=2e-23]; ENSG00000142748, FCN3, ficolin 3, [Score=99.0, Expect=1e-23]; ENSG00000160339, FCN2, ficolin 2, [Score=98.2, Expect=2e-23]} {Mouse: ENSMUSG00000026938, Fcna, ficolin A, [Score=100, Expect=3e-24]} {Dmel: FBgn0034160, CG5550, [Score=97.8, Expect=7e-24]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=90.1, Expect=4e-20]} {RNA1310_67383} {RNA815_45536}
39. MligTC455_32922 646 13.45 Mlig455_037744, Mlig455_069919

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.335

Region-enriched R2: 1.859/0.01146

ANXA4 2.831 - - - 0.956 0.935 0.940

Mlig455_037744 {REF} {Length: 3044} {TRANSSPLICED} {Pfam: Annexin [PF00191.22, score=312.1]; Fn3 associated [PF13287.8, score=30.9]; Chitobiase/beta-hexosaminidase C-terminal domain [PF13290.8, score=27.1]} {Human: ENSG00000196975, ANXA4, annexin A4, [RH, Score=330, Expect=1e-106]; ENSG00000122359, ANXA11, annexin A11, [RH, Score=318, Expect=6e-100]} {Mouse: ENSMUSG00000029994, Anxa4, annexin A4, [RH, Score=328, Expect=2e-106]; ENSMUSG00000021866, Anxa11, annexin A11, [RH, Score=317, Expect=2e-99]} {Dmel: FBgn0030749, AnxB11, Annexin B11, [RH, Score=318, Expect=6e-100]} {Celegans: WBGene00003589, nex-2, Annexin, [RH, Score=298, Expect=7e-93]} {Smed: dd_Smed_v6_5798_0_1, dd_Smed_v6_5798_0_1, [RH, Score=726, Expect=0.0]} {RNA1509_19722} {RNA1310_5582} {RNA815_3942.1}

Mlig455_069919 {REF} {Length: 3044} {TRANSSPLICED} {Pfam: Annexin [PF00191.22, score=308.6]; Fn3 associated [PF13287.8, score=30.9]; Chitobiase/beta-hexosaminidase C-terminal domain [PF13290.8, score=27.1]} {Human: ENSG00000196975, ANXA4, annexin A4, [RH, Score=330, Expect=6e-107]; ENSG00000122359, ANXA11, annexin A11, [RH, Score=316, Expect=3e-99]} {Mouse: ENSMUSG00000029994, Anxa4, annexin A4, [RH, Score=329, Expect=1e-106]; ENSMUSG00000021866, Anxa11, annexin A11, [RH, Score=315, Expect=1e-98]} {Dmel: FBgn0030749, AnxB11, Annexin B11, [RH, Score=316, Expect=3e-99]} {Celegans: WBGene00003589, nex-2, Annexin, [RH, Score=297, Expect=3e-92]} {Smed: dd_Smed_v6_5798_0_1, dd_Smed_v6_5798_0_1, [RH, Score=726, Expect=0.0]} {RNA1509_19722, RNA1509_52903} {RNA1310_5582, RNA1509_19722, RNA1509_52903} {RNA1509_19722, RNA1509_52903, RNA815_3942.1}
40. MligTC455_20126 1086 22.63 Mlig455_049824

Neo: -

Age: -

SLC2A1 2.797 - - - 0.905 0.958 0.934 Mlig455_049824 {REF} {Length: 3566} {Pfam: Sugar (and other) transporter [PF00083.26, score=307.8]; Major Facilitator Superfamily [PF07690.18, score=50.0]} {Human: ENSG00000117394, SLC2A1, solute carrier family 2 member 1, [Score=289, Expect=2e-92]; ENSG00000163581, SLC2A2, solute carrier family 2 member 2, [Score=275, Expect=1e-86]} {Mouse: ENSMUSG00000028645, Slc2a1, solute carrier family 2 (facilitated glucose transporter), member 1, [Score=287, Expect=6e-92]; ENSMUSG00000027690, Slc2a2, solute carrier family 2 (facilitated glucose transporter), member 2, [Score=278, Expect=5e-88]} {Dmel: FBgn0264574, Glut1, Glucose transporter 1, [Score=296, Expect=7e-95]} {Celegans: WBGene00019207, fgt-1, Facilitated glucose transporter protein 1, [Score=239, Expect=1e-73]} {Smed: dd_Smed_v6_4396_0_1, dd_Smed_v6_4396_0_1, [Score=247, Expect=6e-77]} {RNA1509_29953} {RNA1310_18869} {RNA815_4904.1}
41. MligTC455_38568 326 6.8 Mlig455_012690

Neo: -

Age: logFC(26M/2M)=-0.283

PRKX 2.791 - - - 0.913 0.923 0.955 Mlig455_012690 {REF} {Length: 2543} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=233.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=112.3]; Kinase-like [PF14531.8, score=27.5]} {Human: ENSG00000183943, PRKX, protein kinase X-linked, [RH, Score=403, Expect=2e-140]} {Mouse: ENSMUSG00000035725, Prkx, protein kinase, X-linked, [RH, Score=397, Expect=4e-138]} {Dmel: FBgn0000489, Pka-C3, Protein kinase, cAMP-dependent, catalytic subunit 3, [RH, Score=408, Expect=2e-139]} {Celegans: WBGene00018569, F47F2.1, cAMP-dependent protein kinase, catalytic subunit-like, [RH, Score=352, Expect=6e-120]} {Smed: dd_Smed_v6_3838_0_1, dd_Smed_v6_3838_0_1, [RH, Score=477, Expect=1e-170]} {RNA1509_11342, RNA1509_29586, RNA1509_38380} {RNA1310_29225, RNA1509_11342, RNA1509_29586, RNA1509_38380} {RNA1509_11342, RNA1509_29586, RNA1509_38380, RNA815_12092}
42. MligTC455_11494 99 2.06 Mlig455_055605

Neo: -

Age: Down-Up-Down

HS3ST5 2.784 - - - 0.936 0.891 0.957 Mlig455_055605 {REF} {Length: 2196} {Pfam: Sulfotransferase domain [PF00685.29, score=91.7]; Sulfotransferase family [PF13469.8, score=45.8]} {Human: ENSG00000249853, HS3ST5, heparan sulfate-glucosamine 3-sulfotransferase 5, [RH, Score=256, Expect=1e-82]} {Mouse: ENSMUSG00000044499, Hs3st5, heparan sulfate (glucosamine) 3-O-sulfotransferase 5, [RH, Score=257, Expect=2e-83]} {Dmel: FBgn0031005, Hs3st-B, Heparan sulfate 3-O sulfotransferase-B, [Score=205, Expect=9e-63]} {Celegans: WBGene00044303, hst-3.2, Heparan SulphoTransferase, [Score=215, Expect=7e-68]} {Smed: dd_Smed_v6_81402_0_1, dd_Smed_v6_81402_0_1, [Score=123, Expect=7e-34]} {RNA1310_37118} {RNA815_58609}
43. MligTC455_53722 292 6.08 Mlig455_025654

Neo: -

Age: -

2.745 - 0.943 - - 0.827 0.975 Mlig455_025654 {REF} {Length: 1239} {Pfam: Sel1 repeat [PF08238.14, score=31.9]} {Smed: dd_Smed_v6_9387_0_1, dd_Smed_v6_9387_0_1, [RH, Score=194, Expect=2e-62]} {RNA1509_19616} {RNA1310_29567, RNA1509_19616} {RNA1509_19616, RNA815_13742}
44. MligTC455_50935 553 11.53 Mlig455_037656, Mlig455_037661, Mlig455_037766

Neo: -

Age: Down-Up-Up

2.721 - - - 0.886 0.879 0.956

Mlig455_037656 {REF} {Length: 2489} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=150.9]} {Celegans: WBGene00006748, unc-8, Degenerin unc-8, [Score=48.9, Expect=1e-05]} {Smed: dd_Smed_v6_12878_0_1, dd_Smed_v6_12878_0_1, [Score=71.6, Expect=8e-13]} {RNA1509_12261, RNA1509_57275} {RNA1310_8718.2, RNA1509_12261, RNA1509_57275} {RNA1509_12261, RNA1509_57275, RNA815_16423}

Mlig455_037661 {REF} {Length: 2450} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=151.7]} {Celegans: WBGene00006748, unc-8, Degenerin unc-8, [Score=48.9, Expect=1e-05]} {Smed: dd_Smed_v6_12878_0_1, dd_Smed_v6_12878_0_1, [Score=71.6, Expect=8e-13]} {RNA1509_12261} {RNA1310_8718.2} {RNA815_16423}

Mlig455_037766 {REF} {Length: 2439} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=150.9]} {Celegans: WBGene00006748, unc-8, Degenerin unc-8, [Score=48.9, Expect=1e-05]} {Smed: dd_Smed_v6_12878_0_1, dd_Smed_v6_12878_0_1, [Score=71.6, Expect=8e-13]} {RNA1509_12261} {RNA1310_8718.2} {RNA815_16423}
45. MligTC455_54209 196 4.09 Mlig455_005246

Neo: -

Age: logFC(26M/2M)=-0.457

LRRC74A 2.713 - - 0.823 - 0.908 0.982 Mlig455_005246 {REF} {Length: 4154} {Pfam: Leucine Rich repeat [PF13516.8, score=97.2]; Leucine Rich Repeat [PF00560.35, score=29.2]; Leucine Rich repeats (2 copies) [PF12799.9, score=22.2]} {Human: ENSG00000100565, LRRC74A, leucine rich repeat containing 74A, [Score=186, Expect=2e-51]} {Mouse: ENSMUSG00000059114, Lrrc74a, leucine rich repeat containing 74A, [Score=182, Expect=4e-50]} {Celegans: WBGene00009201, F28C1.3, Protein phosphatase 1 regulatory subunit 37 homolog, [Score=80.1, Expect=2e-15]} {Smed: dd_Smed_v6_14506_0_1, dd_Smed_v6_14506_0_1, [RH, Score=369, Expect=3e-120]} {RNA1509_14523, RNA1509_24088} {RNA1310_10119, RNA1509_14523, RNA1509_24088} {RNA1509_14523, RNA1509_24088, RNA815_985}
46. MligTC455_26935 289 6.01 Mlig455_037791

Neo: -

Age: -

2.69 - - - 0.894 0.845 0.951 Mlig455_037791 {REF} {Length: 3234} {Pfam: Innexin [PF00876.20, score=414.3]} {Dmel: FBgn0085387, shakB, shaking B, [Score=127, Expect=2e-31]} {Celegans: WBGene00002123, inx-1, Innexin, [Score=343, Expect=3e-114]} {Smed: dd_Smed_v6_11077_0_2, dd_Smed_v6_11077_0_2, [Score=479, Expect=1e-166]} {RNA1509_20876} {RNA1310_15813} {RNA815_1848.1}
47. MligTC455_44432 1115 23.23 Mlig455_015671, Mlig455_062480

Neo: -

Age: logFC(26M/2M)=0.247

F5 2.682 - - - 0.824 0.892 0.966

Mlig455_015671 {REF} {Length: 5764} {Pfam: F5/8 type C domain [PF00754.27, score=47.5]} {Human: ENSG00000198734, F5, coagulation factor V, [Score=64.3, Expect=2e-09]; ENSG00000185010, F8, coagulation factor VIII, [Score=62.8, Expect=6e-09]} {Mouse: ENSMUSG00000031196, F8, coagulation factor VIII, [Score=69.3, Expect=4e-11]} {Dmel: FBgn0053531, Ddr, Discoidin domain receptor, [Score=50.8, Expect=6e-06]} {Smed: dd_Smed_v6_15631_0_1, dd_Smed_v6_15631_0_1, [Score=87.8, Expect=3e-17]} {RNA1509_2035} {RNA1310_951.1, RNA1509_2035} {RNA1509_2035, RNA815_305}

Mlig455_062480 {REF} {Length: 6260} {Pfam: F5/8 type C domain [PF00754.27, score=47.5]} {Human: ENSG00000198734, F5, coagulation factor V, [Score=64.7, Expect=2e-09]; ENSG00000185010, F8, coagulation factor VIII, [Score=62.0, Expect=1e-08]} {Mouse: ENSMUSG00000031196, F8, coagulation factor VIII, [Score=68.2, Expect=9e-11]} {Dmel: FBgn0053531, Ddr, Discoidin domain receptor, [Score=53.5, Expect=1e-06]} {Smed: dd_Smed_v6_15631_0_1, dd_Smed_v6_15631_0_1, [Score=89.7, Expect=8e-18]} {RNA1509_2035, RNA1509_37215} {RNA1310_951.1, RNA1509_37215} {RNA1509_37215, RNA815_305}
48. MligTC455_38369 100 2.08 Mlig455_026465

Neo: -

Age: -

SSUH2 2.656 - - - 0.819 0.877 0.960 Mlig455_026465 {REF} {Length: 1913} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [RH, Score=238, Expect=2e-74]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [RH, Score=200, Expect=2e-60]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=122, Expect=4e-31]} {RNA1509_6425} {RNA1310_32434} {RNA815_16161}
49. MligTC455_24301 172 3.57 Mlig455_029246

Neo: -

Age: -

KCNQ5 2.646 - - 0.830 0.840 - 0.976 Mlig455_029246 {REF} {Length: 3519} {Pfam: KCNQ voltage-gated potassium channel [PF03520.16, score=122.6]; Ion transport protein [PF00520.33, score=99.3]; Ion channel [PF07885.18, score=51.1]; Putative sensor [PF13796.8, score=18.6]} {Human: ENSG00000185760, KCNQ5, potassium voltage-gated channel subfamily Q member 5, [RH, Score=477, Expect=9e-155]; ENSG00000117013, KCNQ4, potassium voltage-gated channel subfamily Q member 4, [RH, Score=459, Expect=3e-151]} {Mouse: ENSMUSG00000028033, Kcnq5, potassium voltage-gated channel, subfamily Q, member 5, [RH, Score=476, Expect=1e-154]} {Dmel: FBgn0033494, KCNQ, KCNQ potassium channel, [RH, Score=603, Expect=0.0]} {Celegans: WBGene00002233, kqt-1, KQT-1 potassium channel; Potassium channel, KvQLT family, [RH, Score=524, Expect=4e-176]} {Smed: dd_Smed_v6_12681_0_1, dd_Smed_v6_12681_0_1, [RH, Score=639, Expect=0.0]} {RNA1509_34272} {RNA1310_3730.1, RNA1509_34272} {RNA1509_34272, RNA815_2787}
50. MligTC455_40654 676 14.08 Mlig455_056785

Neo: -

Age: logFC(26M/2M)=-0.402

CCDC63 2.639 - - - 0.914 0.763 0.962 Mlig455_056785 {REF} {Length: 2093} {TRANSSPLICED} {Pfam: Initiation control protein YabA [PF06156.15, score=20.5]} {Human: ENSG00000173093, CCDC63, coiled-coil domain containing 63, [RH, Score=190, Expect=9e-53]} {Mouse: ENSMUSG00000043036, Ccdc63, coiled-coil domain containing 63, [RH, Score=179, Expect=7e-49]} {Dmel: FBgn0038452, CG14905, [RH, Score=168, Expect=6e-46]} {Smed: dd_Smed_v6_4191_0_1, dd_Smed_v6_4191_0_1, [RH, Score=442, Expect=7e-150]} {RNA1509_17628} {RNA1310_12386, RNA1509_17628} {RNA1509_17628, RNA815_7054}
51. MligTC455_24061 1104 23.01 Mlig455_017234

Neo: -

Age: -

SNAP25 2.633 - - 0.774 0.903 - 0.956 Mlig455_017234 {REF} {Length: 1658} {Pfam: SNAP-25 family [PF00835.21, score=41.5]} {Human: ENSG00000132639, SNAP25, synaptosome associated protein 25, [Score=219, Expect=7e-72]} {Mouse: ENSMUSG00000027273, Snap25, synaptosomal-associated protein 25, [Score=219, Expect=5e-72]} {Dmel: FBgn0266720, Snap24, Synaptosomal-associated protein 24kDa, [RH, Score=228, Expect=1e-75]} {Celegans: WBGene00004364, ric-4, Synaptosomal-associated protein, [RH, Score=257, Expect=2e-87]} {Smed: dd_Smed_v6_3977_0_1, dd_Smed_v6_3977_0_1, [RH, Score=282, Expect=2e-97]} {RNA1509_25321, RNA1509_8624} {RNA1310_24253, RNA1509_25321, RNA1509_8624} {RNA1509_25321, RNA1509_8624, RNA815_10439}
52. MligTC455_42557 354 7.38 Mlig455_026024

Neo: -

Age: -

2.629 - - 0.801 - 0.961 0.867 Mlig455_026024 {REF} {Length: 1890} {TRANSSPLICED} {RNA1509_23566, RNA1509_54428, RNA1509_56722} {RNA1310_23201.2, RNA1509_23566, RNA1509_54428, RNA1509_56722} {RNA1509_23566, RNA1509_54428, RNA1509_56722, RNA815_9453.1}
53. MligTC455_19266 1038 21.61 Mlig455_004528, Mlig455_028530

Neo: -

Age: -

Region-specific R2: 2.706

Region-enriched R2: 1.766/0.00005

NCALD 2.627 - - - 0.777 0.868 0.982

Mlig455_004528 {REF} {Length: 3958} {tRNA: Val(CAC),pseudo, score=38.6} {Pfam: EF-hand domain pair [PF13499.8, score=74.4]; EF hand [PF00036.34, score=71.3]; EF-hand domain [PF13405.8, score=66.3]; EF hand [PF13202.8, score=62.7]; EF-hand domain pair [PF13833.8, score=50.8]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=22.1]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=19.3]} {Human: ENSG00000104490, NCALD, neurocalcin delta, [Score=194, Expect=4e-63]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=191, Expect=1e-61]; ENSG00000121905, HPCA, hippocalcin, [Score=185, Expect=1e-59]} {Mouse: ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=194, Expect=2e-63]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=191, Expect=8e-62]; ENSMUSG00000028785, Hpca, hippocalcin, [Score=185, Expect=1e-59]} {Dmel: FBgn0036926, CG7646, [RH, Score=221, Expect=6e-74]} {Celegans: WBGene00003564, ncs-2, Neuronal calcium sensor 2, [Score=238, Expect=6e-81]} {Smed: dd_Smed_v6_5266_0_1, dd_Smed_v6_5266_0_1, [RH, Score=359, Expect=8e-129]} {RNA1509_14564} {RNA1310_18405, RNA1509_14564} {RNA1509_14564, RNA815_10180.1}

Mlig455_028530 {REF} {Length: 3453} {tRNA: Val(CAC),pseudo, score=38.6} {Pfam: EF-hand domain pair [PF13499.8, score=74.4]; EF hand [PF00036.34, score=71.3]; EF-hand domain [PF13405.8, score=66.3]; EF hand [PF13202.8, score=62.7]; EF-hand domain pair [PF13833.8, score=50.8]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=22.1]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=19.3]} {Human: ENSG00000104490, NCALD, neurocalcin delta, [Score=194, Expect=4e-63]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=191, Expect=1e-61]; ENSG00000121905, HPCA, hippocalcin, [Score=185, Expect=1e-59]} {Mouse: ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=194, Expect=2e-63]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=191, Expect=8e-62]; ENSMUSG00000028785, Hpca, hippocalcin, [Score=185, Expect=1e-59]} {Dmel: FBgn0036926, CG7646, [RH, Score=221, Expect=6e-74]} {Celegans: WBGene00003564, ncs-2, Neuronal calcium sensor 2, [Score=238, Expect=6e-81]} {Smed: dd_Smed_v6_5266_0_1, dd_Smed_v6_5266_0_1, [RH, Score=359, Expect=8e-129]} {RNA1509_13995, RNA1509_14564, RNA1509_30926} {RNA1310_18405, RNA1509_13995, RNA1509_30926} {RNA1509_13995, RNA1509_30926, RNA815_10180.1}
54. MligTC455_51275 335 6.98 Mlig455_045339

Neo: -

Age: logFC(26M/2M)=-0.374

GRM3 2.625 - - 0.845 0.824 - 0.956 Mlig455_045339 {REF} {Length: 4374} {Pfam: Receptor family ligand binding region [PF01094.30, score=112.7]} {Human: ENSG00000198822, GRM3, glutamate metabotropic receptor 3, [Score=78.2, Expect=7e-14]; ENSG00000164082, GRM2, glutamate metabotropic receptor 2, [Score=76.6, Expect=2e-13]} {Mouse: ENSMUSG00000003974, Grm3, glutamate receptor, metabotropic 3, [Score=75.5, Expect=3e-13]; ENSMUSG00000023192, Grm2, glutamate receptor, metabotropic 2, [Score=73.6, Expect=1e-12]} {Dmel: FBgn0050361, mtt, mangetout, [Score=84.0, Expect=6e-16]} {Celegans: WBGene00021152, mgl-3, Metabotropic GLutamate receptor family, [Score=59.3, Expect=2e-08]} {Smed: dd_Smed_v6_15419_0_1, dd_Smed_v6_15419_0_1, [Score=62.0, Expect=2e-09]} {RNA1509_29529} {RNA1310_2368.1, RNA1509_29529} {RNA1509_29529, RNA815_7926}
55. MligTC455_42780 194 4.05 Mlig455_053699

Neo: -

Age: -

TIA1 2.624 - - 0.832 0.827 - 0.965 Mlig455_053699 {REF} {Length: 2917} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=137.6]; RNA binding motif [PF08777.13, score=27.7]; RNA recognition motif [PF16367.7, score=27.3]; Cytosolic domain of 10TM putative phosphate transporter [PF14703.8, score=22.0]; Nup53/35/40-type RNA recognition motif [PF05172.15, score=19.3]; Nup53/35/40-type RNA recognition motif [PF14605.8, score=19.0]} {Human: ENSG00000116001, TIA1, TIA1 cytotoxic granule associated RNA binding protein, [RH, Score=237, Expect=3e-74]} {Mouse: ENSMUSG00000071337, Tia1, cytotoxic granule-associated RNA binding protein 1, [RH, Score=234, Expect=2e-73]; ENSMUSG00000030846, Tial1, Tia1 cytotoxic granule-associated RNA binding protein-like 1, [RH, Score=225, Expect=2e-70]} {Dmel: FBgn0085391, trv, trivet, [RH, Score=240, Expect=2e-74]} {Celegans: WBGene00015943, tiar-1, TIA-1/TIAL RNA binding protein homolog, [RH, Score=231, Expect=6e-72]} {Smed: dd_Smed_v6_10924_0_1, dd_Smed_v6_10924_0_1, [RH, Score=360, Expect=8e-123]} {RNA1509_20262} {RNA1310_6771, RNA1509_20262} {RNA1509_20262, RNA815_11494}
56. MligTC455_47948 100 2.07 Mlig455_005840

Neo: -

Age: -

Region-enriched R2: 3.643/0.03527

TSPAN16 2.623 - - - 0.773 0.891 0.959 Mlig455_005840 {REF} {Length: 2130} {Pfam: Tetraspanin family [PF00335.22, score=86.4]} {Human: ENSG00000130167, TSPAN16, tetraspanin 16, [Score=48.1, Expect=6e-06]} {Mouse: ENSMUSG00000025351, Cd63, CD63 antigen, [Score=50.4, Expect=7e-07]} {Dmel: FBgn0036769, Tsp74F, Tetraspanin 74F, [Score=68.2, Expect=4e-13]} {Smed: dd_Smed_v6_854_1_1, dd_Smed_v6_854_1_1, [Score=119, Expect=5e-32]} {RNA1509_35459} {RNA1310_22253, RNA1509_35459} {RNA1509_35459, RNA815_11065}
57. MligTC455_44646 193 4.01 Mlig455_013515

Neo: -

Age: Down-Up-Down

SCNN1B 2.616 - - - 0.764 0.893 0.959 Mlig455_013515 {REF} {Length: 2272} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=308.7]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [RH, Score=191, Expect=3e-52]} {Mouse: ENSMUSG00000030873, Scnn1b, sodium channel, nonvoltage-gated 1 beta, [RH, Score=188, Expect=3e-51]} {Dmel: FBgn0030795, ppk28, pickpocket 28, [Score=68.2, Expect=1e-11]} {Celegans: WBGene00012137, asic-2, Degenerin-like protein asic-2, [Score=143, Expect=2e-36]} {Smed: dd_Smed_v6_17021_0_1, dd_Smed_v6_17021_0_1, [Score=175, Expect=2e-47]} {RNA1509_52917} {RNA1310_12013.1, RNA1509_52917} {RNA1509_52917, RNA815_4777}
58. MligTC455_47783 422 8.78 Mlig455_031120

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.635

2.615 - - - 0.815 0.971 0.829 Mlig455_031120 {REF} {Length: 2684} {Pfam: Mab-21 protein [PF03281.16, score=59.6]} {Smed: dd_Smed_v6_43442_0_1, dd_Smed_v6_43442_0_1, [RH, Score=63.2, Expect=1e-10]} {RNA1509_15607} {RNA1310_11311} {RNA815_5452}
59. MligTC455_41694 404 8.41 Mlig455_026434, Mlig455_026464

Neo: -

Age: -

SSUH2 2.614 - - - 0.794 0.951 0.869

Mlig455_026434 {REF} {Length: 1709} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=210, Expect=4e-64]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=177, Expect=5e-52]} {RNA1509_35286} {RNA1310_19837, RNA1509_35286} {RNA1509_35286, RNA815_11262}

Mlig455_026464 {REF} {Length: 1584} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=210, Expect=7e-64]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=178, Expect=4e-52]} {RNA1509_35286} {RNA1310_19837} {RNA815_11262}
60. MligTC455_18564 196 4.08 Mlig455_063527

Neo: -

Age: -

Region-enriched R2: 2.416/0.01839

PRKG2 2.608 0.825 0.822 - - - 0.961 Mlig455_063527 {REF} {Length: 2971} {Pfam: Protein kinase domain [PF00069.27, score=212.4]; Cyclic nucleotide-binding domain [PF00027.31, score=135.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=103.7]; Kinase-like [PF14531.8, score=24.8]} {Human: ENSG00000138669, PRKG2, protein kinase cGMP-dependent 2, [RH, Score=653, Expect=0.0]} {Mouse: ENSMUSG00000029334, Prkg2, protein kinase, cGMP-dependent, type II, [RH, Score=651, Expect=0.0]} {Dmel: FBgn0000442, Pkg21D, Protein kinase, cGMP-dependent at 21D, [RH, Score=662, Expect=0.0]} {Celegans: WBGene00001173, egl-4, cGMP-dependent protein kinase egl-4, [Score=655, Expect=0.0]} {Smed: dd_Smed_v6_6967_0_1, dd_Smed_v6_6967_0_1, [RH, Score=645, Expect=0.0]} {RNA1509_38353} {RNA1310_8466, RNA1509_38353} {RNA1509_38353, RNA815_6313}
61. MligTC455_35478 597 12.43 Mlig455_020720, Mlig455_020788

Neo: -

Age: logFC(26M/2M)=0.408

2.606 - - 0.732 - 0.916 0.958

Mlig455_020720 {REF} {Length: 1135} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_13719} {RNA1310_25325} {RNA815_14669}

Mlig455_020788 {REF} {Length: 1139} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_13719} {RNA1310_25325} {RNA815_14669}
62. MligTC455_54334 582 12.13 Mlig455_034532

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.828/0.00360

CEP135 2.604 - - 0.744 0.900 0.960 - Mlig455_034532 {REF} {Length: 5092} {Pfam: Ezrin/radixin/moesin family [PF00769.21, score=20.7]} {Human: ENSG00000174799, CEP135, centrosomal protein 135, [Score=345, Expect=4e-102]} {Mouse: ENSMUSG00000060771, Tsga10, testis specific 10, [RH, Score=328, Expect=5e-100]} {Dmel: FBgn0036480, Cep135, Centrosomal protein 135kDa, [RH, Score=95.5, Expect=9e-20]} {Smed: dd_Smed_v6_5218_0_1, dd_Smed_v6_5218_0_1, [RH, Score=427, Expect=5e-135]} {RNA1509_41811, RNA1509_42474, RNA1509_50736} {RNA1310_1540, RNA1509_41811, RNA1509_42474, RNA1509_50736} {RNA1509_41811, RNA1509_42474, RNA1509_50736, RNA815_400.1}
63. MligTC455_14904 4225 88.01 Mlig455_037596

Neo: -

Age: logFC(26M/2M)=0.385

Region-enriched R8: 1.541/0.00053

2.592 - - - 0.807 0.814 0.971 Mlig455_037596 {REF} {Length: 2914} {Dmel: FBgn0034294, Muc55B, Mucin 55B, [Score=59.3, Expect=3e-09]} {RNA1509_17730, RNA1509_4337} {RNA1310_7259, RNA1509_17730} {RNA1509_17730, RNA815_206}
64. MligTC455_24759 293 6.11 Mlig455_032990

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.793

PFN4 2.587 - 0.704 - 0.923 - 0.960 Mlig455_032990 {REF} {Length: 1358} {Pfam: Profilin [PF00235.21, score=102.2]} {Human: ENSG00000176732, PFN4, profilin family member 4, [RH, Score=99.4, Expect=3e-27]} {Mouse: ENSMUSG00000020639, Pfn4, profilin family, member 4, [RH, Score=95.9, Expect=4e-26]} {Smed: dd_Smed_v6_2107_0_1, dd_Smed_v6_2107_0_1, [RH, Score=109, Expect=1e-31]} {RNA1509_34639} {RNA1310_16901.2, RNA1509_34639} {RNA1509_34639, RNA815_34827}
65. MligTC455_46438 147 3.07 Mlig455_021783

Neo: -

Age: Up-Down-Down

2.584 - - 0.774 - 0.845 0.965 Mlig455_021783 {REF} {Length: 2899} {RNA1509_36156} {RNA1310_17582, RNA1509_36156} {RNA1509_36156, RNA815_32277}
66. MligTC455_42037 1931 40.23 Mlig455_063391

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.444

Region-specific R2: 2.479

Region-enriched R2: 1.442/0.00136

2.583 - - - 0.822 0.810 0.951 Mlig455_063391 {REF} {Length: 1482} {RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236} {RNA1310_24553, RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236} {RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236, RNA815_11766}
67. MligTC455_17730 125 2.59 Mlig455_008650, Mlig455_069416

Neo: -

Age: Down-Up-Up

CALML3 2.582 - - - 0.766 0.863 0.953

Mlig455_008650 {REF} {Length: 1819} {Pfam: EF hand [PF00036.34, score=110.9]; EF-hand domain pair [PF13499.8, score=105.4]; EF hand [PF13202.8, score=90.8]; EF-hand domain [PF13405.8, score=79.5]; EF-hand domain pair [PF13833.8, score=78.3]; EF-hand domain [PF14658.8, score=38.1]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=33.5]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=31.5]; Dockerin type I domain [PF00404.20, score=24.7]; EF-hand domain [PF08976.13, score=24.2]} {Human: ENSG00000178363, CALML3, calmodulin like 3, [Score=106, Expect=2e-29]; ENSG00000143933, CALM2, calmodulin 2, [Score=103, Expect=9e-28]; ENSG00000198668, CALM1, calmodulin 1, [Score=102, Expect=6e-28]; ENSG00000160014, CALM3, calmodulin 3, [Score=102, Expect=6e-28]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=110, Expect=2e-31]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=105, Expect=3e-29]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=104, Expect=5e-29]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=104, Expect=4e-29]} {RNA1310_77551} {RNA815_27181}

Mlig455_069416 {REF} {Length: 1771} {Pfam: EF hand [PF00036.34, score=110.9]; EF-hand domain pair [PF13499.8, score=105.4]; EF hand [PF13202.8, score=90.8]; EF-hand domain [PF13405.8, score=79.5]; EF-hand domain pair [PF13833.8, score=78.3]; EF-hand domain [PF14658.8, score=38.1]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=33.5]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=31.5]; Dockerin type I domain [PF00404.20, score=24.7]; EF-hand domain [PF08976.13, score=24.2]} {Human: ENSG00000178363, CALML3, calmodulin like 3, [Score=106, Expect=2e-29]; ENSG00000143933, CALM2, calmodulin 2, [Score=103, Expect=9e-28]; ENSG00000198668, CALM1, calmodulin 1, [Score=102, Expect=6e-28]; ENSG00000160014, CALM3, calmodulin 3, [Score=102, Expect=6e-28]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=110, Expect=2e-31]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=105, Expect=3e-29]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=104, Expect=5e-29]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=104, Expect=4e-29]} {RNA1310_77551} {RNA815_27181}
68. MligTC455_45712 91 1.89 Mlig455_050761, Mlig455_050791

Neo: -

Age: -

2.582 0.740 0.883 - - - 0.959

Mlig455_050761 {REF} {Length: 2816} {RNA1509_10628} {RNA1310_39724.1} {RNA815_34935}

Mlig455_050791 {REF} {Length: 2817} {RNA1509_10628} {RNA1310_39724.1} {RNA815_34935}
69. MligTC455_27651 491 10.24 Mlig455_057063

Neo: -

Age: -

ADAM8 2.58 - - 0.963 0.889 - 0.728 Mlig455_057063 {REF} {Length: 3284} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=108.1]; Metallo-peptidase family M12 [PF13688.8, score=46.4]; Disintegrin [PF00200.25, score=45.4]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=40.4]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=36.6]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=29.8]} {Human: ENSG00000151651, ADAM8, ADAM metallopeptidase domain 8, [Score=164, Expect=2e-43]} {Mouse: ENSMUSG00000025473, Adam8, a disintegrin and metallopeptidase domain 8, [Score=167, Expect=1e-44]} {Dmel: FBgn0265140, Meltrin, [Score=133, Expect=5e-33]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=150, Expect=9e-39]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=120, Expect=8e-29]} {RNA1509_4260} {RNA1310_4299.1} {RNA815_11215.1}
70. MligTC455_12278 168 3.5 Mlig455_025499, Mlig455_070508

Neo: -

Age: -

CASP3 2.567 - 0.889 0.718 - - 0.960

Mlig455_025499 {REF} {Length: 4953} {Pfam: Protein kinase domain [PF00069.27, score=199.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=185.8]; Caspase domain [PF00656.24, score=110.9]} {Human: ENSG00000164305, CASP3, caspase 3, [Score=132, Expect=2e-33]; ENSG00000138794, CASP6, caspase 6, [Score=128, Expect=4e-32]} {Mouse: ENSMUSG00000028914, Casp9, caspase 9, [Score=128, Expect=5e-31]; ENSMUSG00000031628, Casp3, caspase 3, [Score=128, Expect=2e-32]; ENSMUSG00000026029, Casp8, caspase 8, [Score=125, Expect=7e-30]; ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=123, Expect=7e-29]; ENSMUSG00000027997, Casp6, caspase 6, [Score=123, Expect=9e-31]} {Dmel: FBgn0010501, Dcp-1, Death caspase-1, [Score=112, Expect=1e-26]} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=131, Expect=1e-33]} {Smed: dd_Smed_v6_10708_0_1, dd_Smed_v6_10708_0_1, [RH, Score=124, Expect=3e-30]} {RNA1509_16483} {RNA1310_10829} {RNA815_3681.1}

Mlig455_070508 {REF} {Length: 4254} {Pfam: Protein kinase domain [PF00069.27, score=198.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=180.9]; Caspase domain [PF00656.24, score=110.8]} {Human: ENSG00000164305, CASP3, caspase 3, [Score=134, Expect=2e-34]} {Mouse: ENSMUSG00000031628, Casp3, caspase 3, [Score=131, Expect=1e-33]; ENSMUSG00000028914, Casp9, caspase 9, [Score=128, Expect=6e-31]} {Dmel: FBgn0010501, Dcp-1, Death caspase-1, [Score=113, Expect=6e-27]} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=130, Expect=3e-33]} {Smed: dd_Smed_v6_10708_0_1, dd_Smed_v6_10708_0_1, [RH, Score=124, Expect=6e-30]} {RNA1509_16483} {RNA1310_10829} {RNA815_3681.1}
71. MligTC455_33996 177 3.68 Mlig455_065865

Neo: -

Age: logFC(26M/2M)=-0.441

2.563 - - 0.705 - 0.954 0.904 Mlig455_065865 {REF} {Length: 5440} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=226.2]; Ankyrin repeats (many copies) [PF13637.8, score=186.3]; Ankyrin repeat [PF13606.8, score=90.6]; Family of unknown function (DUF6189) [PF19688.1, score=74.6]; 3,4-dihydroxy-2-butanone 4-phosphate synthase [PF00926.21, score=47.3]; Phage protein GP46 [PF07409.14, score=42.4]} {RNA1509_28890} {RNA1310_21309.1} {RNA815_12859.1}
72. MligTC455_18787 963 20.06 Mlig455_014022

Neo: -

Age: -

Region-enriched R2: 1.334/0.03482

STRC 2.555 - - - 0.812 0.764 0.979 Mlig455_014022 {REF} {Length: 5754} {Human: ENSG00000242866, STRC, stereocilin, [RH, Score=76.3, Expect=4e-13]} {Mouse: ENSMUSG00000033498, Strc, stereocilin, [RH, Score=80.9, Expect=1e-14]} {RNA1509_4378} {RNA1310_1493.1, RNA1509_4378} {RNA1509_4378, RNA815_804}
73. MligTC455_46306 458 9.55 Mlig455_059663

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.355

Region-enriched R2: 2.126/0.00026

PTBP3 2.55 - - 0.710 0.956 - 0.884 Mlig455_059663 {REF} {Length: 3410} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF13893.8, score=151.4]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=112.0]; RRM-like domain [PF11835.10, score=52.5]; Occluded RNA-recognition motif [PF16842.7, score=43.5]; RNA binding motif [PF08777.13, score=18.6]} {Human: ENSG00000119314, PTBP3, polypyrimidine tract binding protein 3, [RH, Score=466, Expect=9e-157]; ENSG00000011304, PTBP1, polypyrimidine tract binding protein 1, [RH, Score=463, Expect=1e-155]; ENSG00000117569, PTBP2, polypyrimidine tract binding protein 2, [RH, Score=462, Expect=9e-156]} {Mouse: ENSMUSG00000028382, Ptbp3, polypyrimidine tract binding protein 3, [RH, Score=468, Expect=2e-157]; ENSMUSG00000006498, Ptbp1, polypyrimidine tract binding protein 1, [RH, Score=468, Expect=1e-157]; ENSMUSG00000028134, Ptbp2, polypyrimidine tract binding protein 2, [RH, Score=465, Expect=6e-157]} {Dmel: FBgn0011224, heph, hephaestus, [RH, Score=442, Expect=2e-143]} {Celegans: WBGene00004207, ptb-1, PTB (HnRNP) homolog; Putative RNA-binding protein PTB-1b, [RH, Score=422, Expect=4e-139]} {Smed: dd_Smed_v6_14748_0_1, dd_Smed_v6_14748_0_1, [RH, Score=340, Expect=2e-107]} {RNA1509_7362} {RNA1310_5320} {RNA815_1604}
74. MligTC455_18546 418 8.7 Mlig455_044183

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.317

FADS2 2.549 - - 0.728 0.851 - 0.970 Mlig455_044183 {REF} {Length: 2950} {Pfam: Fatty acid desaturase [PF00487.26, score=112.5]; Cytochrome b5-like Heme/Steroid binding domain [PF00173.30, score=37.6]} {Human: ENSG00000134824, FADS2, fatty acid desaturase 2, [Score=117, Expect=3e-28]; ENSG00000221968, FADS3, fatty acid desaturase 3, [Score=114, Expect=6e-27]} {Mouse: ENSMUSG00000024664, Fads3, fatty acid desaturase 3, [Score=119, Expect=5e-29]} {Celegans: WBGene00001395, fat-3, Delta(6)-fatty-acid desaturase fat-3, [Score=131, Expect=2e-33]} {Smed: dd_Smed_v6_10869_0_1, dd_Smed_v6_10869_0_1, [Score=94.0, Expect=9e-21]} {RNA1509_52879} {RNA1310_16890} {RNA815_2888}
75. MligTC455_46313 525 10.93 Mlig455_061072, Mlig455_061118

Neo: -

Age: Down-Up-Down

2.548 - - - 0.768 0.800 0.980

Mlig455_061072 {REF} {Length: 1336} {Pfam: Stathmin family [PF00836.21, score=30.8]} {Smed: dd_Smed_v6_512_0_1, dd_Smed_v6_512_0_1, [Score=63.2, Expect=3e-14]} {RNA1509_8850} {RNA1310_39143} {RNA815_16363}

Mlig455_061118 {REF} {Length: 1813} {Pfam: Stathmin family [PF00836.21, score=27.4]} {Smed: dd_Smed_v6_512_0_1, dd_Smed_v6_512_0_1, [Score=63.5, Expect=2e-14]} {RNA1509_8850} {RNA1310_39143} {RNA815_16363}
76. MligTC455_23599 300 6.25 Mlig455_025579

Neo: -

Age: Up-Down-Down

Region-enriched R8: 3.645/0.00082

FBN2 2.536 - 0.846 - 0.732 - 0.958 Mlig455_025579 {REF} {Length: 10696} {Pfam: Calcium-binding EGF domain [PF07645.17, score=312.2]; Complement Clr-like EGF-like [PF12662.9, score=241.1]; Coagulation Factor Xa inhibitory site [PF14670.8, score=125.1]; EGF domain [PF12947.9, score=95.9]; EGF-like domain [PF00008.29, score=59.7]; Human growth factor-like EGF [PF12661.9, score=47.9]; Thrombospondin type 1 domain [PF00090.21, score=28.9]; MSP1 EGF domain 1 [PF12946.9, score=21.3]} {Human: ENSG00000138829, FBN2, fibrillin 2, [Score=250, Expect=2e-65]; ENSG00000166147, FBN1, fibrillin 1, [Score=248, Expect=1e-64]; ENSG00000142449, FBN3, fibrillin 3, [Score=243, Expect=3e-63]} {Mouse: ENSMUSG00000024598, Fbn2, fibrillin 2, [Score=253, Expect=1e-66]; ENSMUSG00000027204, Fbn1, fibrillin 1, [Score=251, Expect=5e-66]} {Dmel: FBgn0035798, frac, faulty attraction, [RH, Score=238, Expect=3e-62]} {Celegans: WBGene00001403, fbl-1, Fibulin-1, [Score=192, Expect=3e-50]} {Smed: dd_Smed_v6_2649_0_2, dd_Smed_v6_2649_0_2, [Score=294, Expect=3e-79]} {RNA1509_13106} {RNA1310_487} {RNA815_5734}
77. MligTC455_51050 155 3.22 Mlig455_010441

Neo: -

Age: -

PKD2 2.534 - - 0.746 0.828 - 0.960 Mlig455_010441 {REF} {Length: 3821} {Pfam: Polycystin cation channel [PF08016.14, score=402.9]; Ion transport protein [PF00520.33, score=69.5]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [Score=553, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [Score=553, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=268, Expect=4e-77]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=278, Expect=3e-82]} {Smed: dd_Smed_v6_9977_0_1, dd_Smed_v6_9977_0_1, [Score=497, Expect=4e-165]} {RNA1509_39669} {RNA1310_38119.1, RNA1509_39669} {RNA1509_39669, RNA815_9047}
78. MligTC455_24536 120 2.5 Mlig455_028895

Neo: -

Age: Up-Down-Down

TRPA1 2.528 - - - 0.778 0.799 0.951 Mlig455_028895 {REF} {Length: 4399} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=276.9]; Ankyrin repeats (many copies) [PF13637.8, score=235.5]; Ankyrin repeats (many copies) [PF13857.8, score=187.3]; Ankyrin repeat [PF00023.32, score=185.3]; Ankyrin repeat [PF13606.8, score=184.2]; Ion transport protein [PF00520.33, score=31.3]} {Human: ENSG00000104321, TRPA1, transient receptor potential cation channel subfamily A member 1, [Score=295, Expect=6e-83]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=277, Expect=4e-77]} {Dmel: FBgn0035934, TrpA1, Transient receptor potential cation channel A1, [Score=305, Expect=2e-86]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=276, Expect=1e-76]} {Smed: dd_Smed_v6_20683_0_1, dd_Smed_v6_20683_0_1, [RH, Score=551, Expect=2e-178]} {RNA1509_56559} {RNA1310_3837.1} {RNA815_4441}
79. MligTC455_29119 68 1.42 Mlig455_050458

Neo: -

Age: -

Region-enriched R2: 5.525/0.01281

2.521 0.751 - 0.798 - - 0.972 Mlig455_050458 {REF} {Length: 624} {RNA1509_53840} {RNA1310_67192} {RNA815_27042}
80. MligTC455_40118 72 1.5 Mlig455_001236

Neo: -

Age: -

KCNIP4 2.516 - - 0.729 - 0.824 0.963 Mlig455_001236 {REF} {Length: 1284} {Pfam: EF-hand domain pair [PF13499.8, score=42.4]; EF hand [PF00036.34, score=38.6]; EF-hand domain [PF13405.8, score=33.5]; EF hand [PF13202.8, score=31.2]; EF-hand domain pair [PF13833.8, score=28.7]} {Human: ENSG00000185774, KCNIP4, potassium voltage-gated channel interacting protein 4, [Score=122, Expect=2e-32]; ENSG00000182132, KCNIP1, potassium voltage-gated channel interacting protein 1, [Score=122, Expect=2e-32]; ENSG00000115041, KCNIP3, potassium voltage-gated channel interacting protein 3, [Score=119, Expect=1e-30]} {Mouse: ENSMUSG00000053519, Kcnip1, Kv channel-interacting protein 1, [Score=124, Expect=5e-33]; ENSMUSG00000029088, Kcnip4, Kv channel interacting protein 4, [Score=122, Expect=1e-32]} {Dmel: FBgn0013303, Nca, Neurocalcin, [Score=100, Expect=6e-25]} {Celegans: WBGene00003563, ncs-1, Neuronal calcium sensor 1, [Score=103, Expect=5e-26]} {Smed: dd_Smed_v6_9727_0_1, dd_Smed_v6_9727_0_1, [Score=122, Expect=8e-33]} {RNA1310_43225} {RNA815_33406}
81. MligTC455_34925 183 3.82 Mlig455_012715

Neo: -

Age: -

CDKL1 2.514 - - 0.725 0.818 - 0.971 Mlig455_012715 {REF} {Length: 2370} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=250.2]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=120.6]; RIO1 family [PF01163.24, score=23.0]; ABC1 atypical kinase-like domain [PF03109.18, score=20.8]; Haspin like kinase domain [PF12330.10, score=20.4]; Kinase-like [PF14531.8, score=19.4]} {Human: ENSG00000100490, CDKL1, cyclin dependent kinase like 1, [RH, Score=437, Expect=3e-153]; ENSG00000205111, CDKL4, cyclin dependent kinase like 4, [RH, Score=424, Expect=2e-147]} {Mouse: ENSMUSG00000020990, Cdkl1, cyclin-dependent kinase-like 1 (CDC2-related kinase), [RH, Score=437, Expect=2e-153]; ENSMUSG00000033966, Cdkl4, cyclin-dependent kinase-like 4, [RH, Score=432, Expect=2e-151]} {Dmel: FBgn0031730, CG7236, [RH, Score=384, Expect=3e-131]} {Celegans: WBGene00012779, cdkl-1, Cyclin-Dependent Kinase-Like, [RH, Score=388, Expect=3e-132]} {Smed: dd_Smed_v6_9353_0_1, dd_Smed_v6_9353_0_1, [RH, Score=472, Expect=5e-167]} {RNA1509_44617} {RNA1310_15038, RNA1509_44617} {RNA1509_44617, RNA815_6379}
82. MligTC455_18619 527 10.97 Mlig455_030641, Mlig455_030999

Neo: -

Age: -

COL6A5 2.51 - - - 0.763 0.787 0.960

Mlig455_030641 {REF} {Length: 2413} {Pfam: Collagen triple helix repeat (20 copies) [PF01391.20, score=111.9]} {Human: ENSG00000172752, COL6A5, collagen type VI alpha 5 chain, [Score=129, Expect=6e-31]} {Mouse: ENSMUSG00000032572, Col6a4, collagen, type VI, alpha 4, [Score=96.7, Expect=2e-20]; ENSMUSG00000028197, Col24a1, collagen, type XXIV, alpha 1, [Score=95.5, Expect=5e-20]} {Dmel: FBgn0000299, Col4a1, Collagen type IV alpha 1, [Score=91.3, Expect=7e-19]} {Celegans: WBGene00000708, col-135, COLlagen, [Score=99.0, Expect=1e-21]} {Smed: dd_Smed_v6_9565_0_1, dd_Smed_v6_9565_0_1, [Score=111, Expect=2e-25]} {RNA1509_35455} {RNA1310_11079.1} {RNA815_14901}

Mlig455_030999 {REF} {Length: 2379} {Pfam: Collagen triple helix repeat (20 copies) [PF01391.20, score=97.0]} {Human: ENSG00000172752, COL6A5, collagen type VI alpha 5 chain, [Score=117, Expect=9e-27]} {Mouse: ENSMUSG00000031502, Col4a1, collagen, type IV, alpha 1, [Score=95.5, Expect=5e-20]; ENSMUSG00000026390, Marco, macrophage receptor with collagenous structure, [Score=91.7, Expect=3e-19]} {Dmel: FBgn0016075, vkg, viking, [Score=83.6, Expect=2e-16]} {Celegans: WBGene00000708, col-135, COLlagen, [Score=90.9, Expect=5e-19]} {Smed: dd_Smed_v6_9565_0_1, dd_Smed_v6_9565_0_1, [Score=105, Expect=1e-23]} {RNA1509_35455} {RNA1310_15043} {RNA815_14901}
83. MligTC455_38368 107 2.24 Mlig455_026435, Mlig455_044757

Neo: -

Age: Up-Down-Down

SSUH2 2.505 - - - 0.818 0.731 0.956

Mlig455_026435 {REF} {Length: 1789} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [RH, Score=233, Expect=1e-72]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [RH, Score=195, Expect=1e-58]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=117, Expect=3e-29]} {RNA1509_6425} {RNA1310_32434} {RNA815_16161}

Mlig455_044757 {REF} {Length: 883} {TRANSSPLICED} {RNA1509_28356} {RNA1310_61125} {RNA815_53103}
84. MligTC455_24519 1035 21.55 Mlig455_026505

Neo: -

Age: Up-Down-Down

Region-enriched R2: 1.364/0.03756

DNAH10 2.501 - - 0.725 0.957 0.819 - Mlig455_026505 {REF} {Length: 14733} {Pfam: Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=521.9]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=390.5]; P-loop containing dynein motor region D4 [PF12780.9, score=341.0]; Dynein heavy chain C-terminal domain [PF18199.3, score=306.8]; ATP-binding dynein motor region [PF12781.9, score=282.5]; P-loop containing dynein motor region [PF12775.9, score=264.2]; Microtubule-binding stalk of dynein motor [PF12777.9, score=214.4]; Dynein heavy chain AAA lid domain [PF18198.3, score=174.9]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=142.3]; AAA domain (dynein-related subfamily) [PF07728.16, score=92.9]; Dynein heavy chain AAA lid domain [PF17852.3, score=81.8]; AAA+ lid domain [PF17857.3, score=63.2]; AAA domain [PF13401.8, score=44.6]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=34.7]; AAA ATPase domain [PF13191.8, score=31.6]; AAA domain [PF13238.8, score=24.7]; MoxR domain in the MoxR-vWA-beta-propeller ternary systems [PF20030.1, score=21.4]; Sigma-54 interaction domain [PF00158.28, score=21.3]} {Human: ENSG00000281935, DNAH10, dynein axonemal heavy chain 10, [RH, Score=4662, Expect=0.0]} {Mouse: ENSMUSG00000038011, Dnah10, dynein, axonemal, heavy chain 10, [Score=4676, Expect=0.0]} {Dmel: FBgn0013813, Dhc98D, Dynein heavy chain at 89D, [RH, Score=3860, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=1408, Expect=0.0]} {Smed: dd_Smed_v6_5169_0_1, dd_Smed_v6_5169_0_1, [RH, Score=4698, Expect=0.0]} {RNA1509_19877, RNA1509_2715, RNA1509_29080, RNA1509_395} {RNA1310_40.1, RNA1509_19877, RNA1509_2715, RNA1509_29080, RNA1509_395} {RNA1509_19877, RNA1509_2715, RNA1509_29080, RNA1509_395, RNA815_20}
85. MligTC455_14831 280 5.83 Mlig455_067864

Neo: -

Age: Up-Down-Up

Region-enriched R2: 3.261/0.00352

SSUH2 2.499 - - 0.772 0.757 - 0.970 Mlig455_067864 {REF} {Length: 1575} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=184, Expect=6e-54]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=148, Expect=7e-41]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=118, Expect=1e-29]} {RNA1509_46058} {RNA1310_5028.1} {RNA815_5650}
86. MligTC455_39099 2631 54.81 Mlig455_057941, Mlig455_057974, Mlig455_070742

Neo: -

Age: logFC(26M/2M)=-0.384

Region-enriched R4: 1.433/0.02316

SLIT3 2.493 - 0.829 - 0.710 - 0.954

Mlig455_057941 {REF} {Length: 4420} {Pfam: Leucine rich repeat [PF13855.8, score=54.4]; Leucine Rich repeats (2 copies) [PF12799.9, score=30.0]; Leucine Rich Repeat [PF00560.35, score=20.6]; Leucine-rich repeat [PF14580.8, score=19.0]} {Human: ENSG00000184347, SLIT3, slit guidance ligand 3, [Score=62.0, Expect=3e-09]; ENSG00000156564, LRFN2, leucine rich repeat and fibronectin type III domain containing 2, [Score=60.1, Expect=9e-09]} {Mouse: ENSMUSG00000056427, Slit3, slit guidance ligand 3, [Score=63.9, Expect=5e-10]; ENSMUSG00000040490, Lrfn2, leucine rich repeat and fibronectin type III domain containing 2, [Score=60.8, Expect=3e-09]} {Dmel: FBgn0023095, caps, capricious, [Score=56.6, Expect=5e-08]} {Celegans: WBGene00020693, lron-8, ELRR (Extracellular Leucine-Rich Repeat) ONly, [Score=49.7, Expect=4e-06]} {Smed: dd_Smed_v6_13558_0_1, dd_Smed_v6_13558_0_1, [Score=118, Expect=3e-28]} {RNA1509_8042} {RNA1310_9830} {RNA815_3323}

Mlig455_057974 {REF} {Length: 4420} {Pfam: Leucine rich repeat [PF13855.8, score=54.4]; Leucine Rich repeats (2 copies) [PF12799.9, score=30.0]; Leucine Rich Repeat [PF00560.35, score=20.6]; Leucine-rich repeat [PF14580.8, score=19.0]} {Human: ENSG00000184347, SLIT3, slit guidance ligand 3, [Score=62.0, Expect=3e-09]; ENSG00000156564, LRFN2, leucine rich repeat and fibronectin type III domain containing 2, [Score=60.1, Expect=9e-09]} {Mouse: ENSMUSG00000056427, Slit3, slit guidance ligand 3, [Score=63.9, Expect=5e-10]; ENSMUSG00000040490, Lrfn2, leucine rich repeat and fibronectin type III domain containing 2, [Score=60.8, Expect=3e-09]} {Dmel: FBgn0023095, caps, capricious, [Score=56.6, Expect=5e-08]} {Celegans: WBGene00020693, lron-8, ELRR (Extracellular Leucine-Rich Repeat) ONly, [Score=49.7, Expect=4e-06]} {Smed: dd_Smed_v6_13558_0_1, dd_Smed_v6_13558_0_1, [Score=118, Expect=3e-28]} {RNA1509_8042} {RNA1310_9830} {RNA815_3323}

Mlig455_070742 {REF} {Length: 4437} {Pfam: Leucine rich repeat [PF13855.8, score=54.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=30.6]; Leucine Rich Repeat [PF00560.35, score=21.4]; Leucine-rich repeat [PF14580.8, score=19.3]} {Human: ENSG00000184347, SLIT3, slit guidance ligand 3, [Score=62.4, Expect=2e-09]; ENSG00000156564, LRFN2, leucine rich repeat and fibronectin type III domain containing 2, [Score=60.5, Expect=6e-09]} {Mouse: ENSMUSG00000056427, Slit3, slit guidance ligand 3, [Score=64.3, Expect=3e-10]; ENSMUSG00000036334, Igsf10, immunoglobulin superfamily, member 10, [Score=61.2, Expect=3e-09]; ENSMUSG00000040490, Lrfn2, leucine rich repeat and fibronectin type III domain containing 2, [Score=61.2, Expect=2e-09]} {Dmel: FBgn0023095, caps, capricious, [Score=56.6, Expect=4e-08]} {Celegans: WBGene00020693, lron-8, ELRR (Extracellular Leucine-Rich Repeat) ONly, [Score=49.7, Expect=3e-06]} {Smed: dd_Smed_v6_13558_0_1, dd_Smed_v6_13558_0_1, [Score=116, Expect=1e-27]} {RNA1509_17236, RNA1509_20558, RNA1509_8042} {RNA1310_9830, RNA1509_17236, RNA1509_20558, RNA1509_8042} {RNA1509_17236, RNA1509_20558, RNA1509_8042, RNA815_3323}
87. MligTC455_10416 765 15.93 Mlig455_008958

Neo: -

Age: -

Region-enriched R8: 1.474/0.04842

2.457 - 0.804 0.702 - 0.951 - Mlig455_008958 {REF} {Length: 515} {NoTransDecoderORF} {RNA1310_120997} {RNA815_53530}
88. MligTC455_14130 101 2.11 Mlig455_028802

Neo: -

Age: -

Region-enriched R7: 4.171/0.00325

2.453 - - - 0.777 0.717 0.959 Mlig455_028802 {REF} {Length: 1282} {Pfam: Lectin C-type domain [PF00059.23, score=21.4]} {RNA1509_20946} {RNA1310_33562} {RNA815_30982}
89. MligTC455_35258 2779 57.89 Mlig455_040964

Neo: -

Age: Up-Down-Down

Region-specific R2: 2.469

Region-enriched R2: 1.501/0.00133

2.441 - - - 0.733 0.755 0.953 Mlig455_040964 {REF} {Length: 8259} {Smed: dd_Smed_v6_8425_0_1, dd_Smed_v6_8425_0_1, [Score=543, Expect=9e-160]} {RNA1509_16633, RNA1509_52679} {RNA1310_236.2, RNA1509_16633} {RNA1509_16633, RNA815_77.1}
90. MligTC455_41669 480 10.01 Mlig455_040778, Mlig455_064613

Neo: -

Age: Down-Down-Up

2.411 0.716 - - 0.740 - 0.955

Mlig455_040778 {REF} {Length: 2233} {RNA1310_31511} {RNA815_21534}

Mlig455_064613 {REF} {Length: 1332} {RNA1310_32935} {RNA815_21534}
91. MligTC455_27689 21816 454.5 Mlig455_035623

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.278

TUBA1A 2.405 - - 0.712 0.957 0.736 - Mlig455_035623 {REF} {Length: 2313} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=213.7]; Tubulin C-terminal domain [PF03953.19, score=176.0]; Tubulin domain [PF14881.8, score=19.3]} {Human: ENSG00000167552, TUBA1A, tubulin alpha 1a, [Score=854, Expect=0.0]; ENSG00000123416, TUBA1B, tubulin alpha 1b, [Score=853, Expect=0.0]; ENSG00000075886, TUBA3D, tubulin alpha 3d, [Score=845, Expect=0.0]; ENSG00000198033, TUBA3C, tubulin alpha 3c, [Score=845, Expect=0.0]} {Mouse: ENSMUSG00000072235, Tuba1a, tubulin, alpha 1A, [Score=854, Expect=0.0]; ENSMUSG00000023004, Tuba1b, tubulin, alpha 1B, [Score=853, Expect=0.0]; ENSMUSG00000067338, Tuba3b, tubulin, alpha 3B, [Score=845, Expect=0.0]; ENSMUSG00000067702, Tuba3a, tubulin, alpha 3A, [Score=845, Expect=0.0]} {Dmel: FBgn0003885, alphaTub84D, alpha-Tubulin at 84D, [Score=837, Expect=0.0]} {Celegans: WBGene00003175, mec-12, Tubulin alpha-3 chain Detyrosinated tubulin alpha-3 chain, [Score=776, Expect=0.0]} {Smed: dd_Smed_v6_10947_0_2, dd_Smed_v6_10947_0_2, [Score=852, Expect=0.0]} {RNA1509_17783} {RNA1310_26095} {RNA815_3971.1}
92. MligTC455_31095 322 6.71 Mlig455_013789

Neo: -

Age: logFC(26M/2M)=0.396

Region-enriched R8: 3.245/0.00236

TRPA1 1.908 - - - - 0.950 0.958 Mlig455_013789 {REF} {Length: 4115} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=243.4]; Ankyrin repeats (many copies) [PF13637.8, score=217.2]; Ankyrin repeat [PF00023.32, score=188.8]; Ankyrin repeats (many copies) [PF13857.8, score=188.8]; Ankyrin repeat [PF13606.8, score=182.5]; Ion transport protein [PF00520.33, score=39.5]} {Human: ENSG00000104321, TRPA1, transient receptor potential cation channel subfamily A member 1, [Score=281, Expect=5e-78]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=265, Expect=7e-73]} {Dmel: FBgn0035934, TrpA1, Transient receptor potential cation channel A1, [Score=320, Expect=2e-91]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=269, Expect=4e-74]} {Smed: dd_Smed_v6_20683_0_1, dd_Smed_v6_20683_0_1, [Score=482, Expect=9e-152]} {RNA1509_56707, RNA1509_8449} {RNA1310_3264.1, RNA1509_56707, RNA1509_8449} {RNA1509_56707, RNA1509_8449, RNA815_808.1}
93. MligTC455_14180 139 2.89 Mlig455_043810

Neo: -

Age: Down-Up-Up

1.892 - - - 0.927 - 0.965 Mlig455_043810 {REF} {Length: 1531} {RNA1509_15671} {RNA1310_24777} {RNA815_10623}
94. MligTC455_43353 428 8.91 Mlig455_003476

Neo: -

Age: -

1.885 - - - - 0.968 0.917 Mlig455_003476 {REF} {Length: 2887} {Smed: dd_Smed_v6_9265_0_1, dd_Smed_v6_9265_0_1, [Score=108, Expect=2e-26]} {RNA1509_49114, RNA1509_59769} {RNA1310_21358, RNA1509_49114, RNA1509_59769} {RNA1509_49114, RNA1509_59769, RNA815_21652}
95. MligTC455_50660 81 1.7 Mlig455_019591

Neo: -

Age: -

SLC9B2 1.877 - - - - 0.923 0.954 Mlig455_019591 {REF} {Length: 2686} {Pfam: Sodium/hydrogen exchanger family [PF00999.23, score=30.0]} {Human: ENSG00000164038, SLC9B2, solute carrier family 9 member B2, [Score=124, Expect=1e-31]} {Mouse: ENSMUSG00000037994, Slc9b2, solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2, [Score=116, Expect=1e-28]; ENSMUSG00000050150, Slc9b1, solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1, [Score=112, Expect=2e-27]} {Dmel: FBgn0263390, Nha2, Na[+]/H[+] hydrogen antiporter 2, [Score=113, Expect=1e-27]} {Celegans: WBGene00009618, F41E7.2, [Score=70.9, Expect=2e-13]} {Smed: dd_Smed_v6_7736_0_1, dd_Smed_v6_7736_0_1, [Score=148, Expect=1e-43]} {RNA1509_34461} {RNA1310_39553.1} {RNA815_32589}
96. MligTC455_29050 162 3.38 Mlig455_004578

Neo: -

Age: -

TMEM30A 1.865 - - - 0.897 - 0.968 Mlig455_004578 {REF} {Length: 3215} {TRANSSPLICED} {Pfam: LEM3 (ligand-effect modulator 3) family / CDC50 family [PF03381.17, score=266.2]} {Human: ENSG00000112697, TMEM30A, transmembrane protein 30A, [Score=210, Expect=3e-64]} {Mouse: ENSMUSG00000032328, Tmem30a, transmembrane protein 30A, [Score=214, Expect=4e-66]} {Dmel: FBgn0030752, CG9947, [Score=253, Expect=1e-81]} {Celegans: WBGene00019946, chat-1, CDC50 family protein chat-1, [Score=218, Expect=8e-68]} {Smed: dd_Smed_v6_6430_0_1, dd_Smed_v6_6430_0_1, [Score=258, Expect=9e-84]} {RNA1509_38539} {RNA1310_9371} {RNA815_12157}
97. MligTC455_16895 508 10.58 Mlig455_020558, Mlig455_044511

Neo: -

Age: Up-Down-Down

Region-enriched R8: 4.020/0.00009
Region-enriched R7: 2.782/0.03064

FAT4 1.864 - - - 0.897 0.967 -

Mlig455_020558 {REF} {Length: 15261} {Pfam: Cadherin domain [PF00028.19, score=236.6]; EGF-like domain [PF00008.29, score=31.7]; Laminin G domain [PF02210.26, score=27.3]; Laminin G domain [PF00054.25, score=27.1]; Long Rib domain [PF18957.2, score=19.5]} {Human: ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=523, Expect=9e-151]} {Mouse: ENSMUSG00000046743, Fat4, FAT atypical cadherin 4, [Score=509, Expect=1e-146]} {Dmel: FBgn0001075, ft, fat, [Score=503, Expect=2e-144]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=234, Expect=2e-61]} {Smed: dd_Smed_v6_12707_0_1, dd_Smed_v6_12707_0_1, [Score=298, Expect=7e-81]} {RNA1509_19257} {RNA1310_36936, RNA1509_19257} {RNA1509_19257, RNA815_35431}

Mlig455_044511 {REF} {Length: 14996} {Pfam: Cadherin domain [PF00028.19, score=1056.4]; Cadherin-like [PF16184.7, score=66.3]; Cadherin-like [PF08266.14, score=54.7]; EGF-like domain [PF00008.29, score=28.9]; Long Rib domain [PF18957.2, score=27.4]; Cadherin prodomain like [PF08758.13, score=26.9]; Laminin G domain [PF00054.25, score=22.3]} {Human: ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=1341, Expect=0.0]} {Mouse: ENSMUSG00000046743, Fat4, FAT atypical cadherin 4, [Score=1291, Expect=0.0]} {Dmel: FBgn0001075, ft, fat, [Score=726, Expect=0.0]} {Celegans: WBGene00000396, cdh-4, Cadherin-4, [Score=303, Expect=2e-81]} {Smed: dd_Smed_v6_12707_0_1, dd_Smed_v6_12707_0_1, [Score=280, Expect=1e-74]} {RNA1509_19257, RNA1509_53071} {RNA1310_36936, RNA1509_53071} {RNA1509_53071, RNA815_35431}
98. MligTC455_51903 1283 26.73 Mlig455_021657, Mlig455_067458

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.872

CHRNB1, CHRNB3 1.857 - - - 0.902 0.955 -

Mlig455_021657 {REF} {Length: 2044} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=147.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=73.5]} {Human: ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=193, Expect=5e-56]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=189, Expect=1e-54]} {Mouse: ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=187, Expect=8e-54]; ENSMUSG00000035594, Chrna5, cholinergic receptor, nicotinic, alpha polypeptide 5, [Score=186, Expect=1e-53]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=179, Expect=5e-51]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [Score=176, Expect=3e-49]} {Celegans: WBGene00006774, unc-38, Acetylcholine receptor subunit alpha-type unc-38, [Score=174, Expect=9e-49]} {Smed: dd_Smed_v6_2019_0_1, dd_Smed_v6_2019_0_1, [Score=346, Expect=9e-116]} {RNA1509_8724} {RNA1310_17144.1, RNA1509_8724} {RNA1509_8724, RNA815_6285}

Mlig455_067458 {REF} {Length: 1512} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=43.5]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=18.7]} {Human: ENSG00000283946, CHRNB1, cholinergic receptor nicotinic beta 1 subunit, [Score=48.1, Expect=7e-06]; ENSG00000170175, CHRNB1, cholinergic receptor nicotinic beta 1 subunit, [Score=48.1, Expect=7e-06]; ENSG00000117971, CHRNB4, cholinergic receptor nicotinic beta 4 subunit, [Score=47.8, Expect=1e-05]} {Mouse: ENSMUSG00000029205, Chrna9, cholinergic receptor, nicotinic, alpha polypeptide 9, [Score=47.4, Expect=1e-05]} {Celegans: WBGene00000055, acr-16, Acetylcholine receptor subunit alpha-type acr-16, [Score=46.6, Expect=1e-05]} {Smed: dd_Smed_v6_2019_0_1, dd_Smed_v6_2019_0_1, [Score=96.7, Expect=1e-22]} {RNA1509_8724} {RNA1310_17144.1} {RNA815_6285}
99. MligTC455_51473 175 3.64 Mlig455_033087

Neo: -

Age: Up-Down-Up

LITAF 1.852 - - - 0.884 - 0.968 Mlig455_033087 {REF} {Length: 2038} {Pfam: LITAF-like zinc ribbon domain [PF10601.11, score=90.8]} {Human: ENSG00000189067, LITAF, lipopolysaccharide induced TNF factor, [Score=75.5, Expect=6e-17]; ENSG00000274336, CDIP1, cell death inducing p53 target 1, [Score=73.9, Expect=3e-16]; ENSG00000089486, CDIP1, cell death inducing p53 target 1, [Score=73.9, Expect=3e-16]} {Mouse: ENSMUSG00000022500, Litaf, LPS-induced TN factor, [Score=79.3, Expect=1e-18]} {Dmel: FBgn0052280, CG32280, [Score=72.0, Expect=3e-16]} {Celegans: WBGene00009484, F36G3.3, [Score=65.5, Expect=9e-14]} {Smed: dd_Smed_v6_26606_0_1, dd_Smed_v6_26606_0_1, [RH, Score=84.0, Expect=2e-21]} {RNA1310_45914} {RNA815_12450}
100. MligTC455_06865 658 13.71 Mlig455_028132, Mlig455_028276

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.391

KCNC1 1.849 - - - 0.899 - 0.950

Mlig455_028132 {REF} {Length: 2953} {Pfam: Ion transport protein [PF00520.33, score=118.6]; BTB/POZ domain [PF02214.24, score=80.7]; Ion channel [PF07885.18, score=39.5]} {Human: ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [Score=281, Expect=8e-86]; ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=278, Expect=1e-83]} {Mouse: ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [Score=281, Expect=6e-86]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=272, Expect=1e-81]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=293, Expect=2e-91]} {Celegans: WBGene00008819, shw-1, SHaW family of potassium channels, [Score=296, Expect=3e-91]} {Smed: dd_Smed_v6_9740_0_1, dd_Smed_v6_9740_0_1, [Score=307, Expect=8e-96]} {RNA1509_33421, RNA1509_45695} {RNA1310_6306, RNA1509_33421, RNA1509_45695} {RNA1509_33421, RNA1509_45695, RNA815_9610}

Mlig455_028276 {REF} {Length: 2587} {Pfam: BTB/POZ domain [PF02214.24, score=80.8]; Ion transport protein [PF00520.33, score=77.8]; Ion channel [PF07885.18, score=33.2]} {Human: ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [Score=220, Expect=2e-63]} {Mouse: ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [Score=220, Expect=2e-63]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=217, Expect=2e-62]} {Celegans: WBGene00008819, shw-1, SHaW family of potassium channels, [Score=220, Expect=2e-64]} {Smed: dd_Smed_v6_9740_0_1, dd_Smed_v6_9740_0_1, [Score=223, Expect=5e-65]} {RNA1509_33421} {RNA1310_6306} {RNA815_9610}

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