Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_50025 | 312 | 6.51 | Mlig455_041593 | Neo: - Age: - Region-enriched R4: 2.535/0.01468 |
ATF7IP | Mlig455_041593 {REF} {Length: 4601} {TRANSSPLICED} {Pfam: Fibronectin-III type domain [PF16794.7, score=92.7]} {Human: ENSG00000171681, ATF7IP, activating transcription factor 7 interacting protein, [RH, Score=103, Expect=8e-22]} {Mouse: ENSMUSG00000030213, Atf7ip, activating transcription factor 7 interacting protein, [RH, Score=101, Expect=2e-21]} {Dmel: FBgn0027499, wde, windei, [RH, Score=90.9, Expect=4e-18]} {Smed: dd_Smed_v6_9372_0_1, dd_Smed_v6_9372_0_1, [RH, Score=76.6, Expect=1e-14]} {RNA1509_10271} {RNA1310_5928.1} {RNA815_4314.1} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -6.136 | 3.14 | 0.12065 | 0.71390 | |
RegionR2 | -0.871 | 3.14 | 0.98198 | 1.00000 | |
RegionR3 | -0.027 | 3.14 | 0.86015 | 1.00000 | |
RegionR4 | 2.535 | 3.14 | 0.00155 | 0.01468 | |
RegionR5 | 1.415 | 3.14 | 0.04453 | 0.17235 | |
RegionR6 | 0.975 | 3.14 | 0.23533 | 0.81885 | |
RegionR7 | 1.521 | 3.14 | 0.06460 | 0.48825 | |
RegionR8 | 0.588 | 3.14 | 0.60768 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -0.192 | 3.14 | 1.00000 | 1.00000 | |
RegenerationR2 | -0.1 | 3.14 | 0.83721 | 1.00000 | |
RegenerationR3 | -0.163 | 3.14 | 0.77061 | 0.97177 | |
RegenerationR4 | -0.99 | 3.14 | 0.07162 | 0.42514 | |
RegenerationR5 | -0.703 | 3.14 | 0.14551 | 0.56121 | |
RegenerationR6 | -0.239 | 3.14 | 0.63810 | 0.89196 | |
RegenerationBL | -0.046 | 3.14 | 0.93562 | 1.00000 | |
RegenerationTP | -1.682 | 3.14 | 0.03872 | 0.32823 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_50025 | 312 | 6.51 | Mlig455_041593 | Neo: - Age: - Region-enriched R4: 2.535/0.01468 |
ATF7IP | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_041593 {REF} {Length: 4601} {TRANSSPLICED} {Pfam: Fibronectin-III type domain [PF16794.7, score=92.7]} {Human: ENSG00000171681, ATF7IP, activating transcription factor 7 interacting protein, [RH, Score=103, Expect=8e-22]} {Mouse: ENSMUSG00000030213, Atf7ip, activating transcription factor 7 interacting protein, [RH, Score=101, Expect=2e-21]} {Dmel: FBgn0027499, wde, windei, [RH, Score=90.9, Expect=4e-18]} {Smed: dd_Smed_v6_9372_0_1, dd_Smed_v6_9372_0_1, [RH, Score=76.6, Expect=1e-14]} {RNA1509_10271} {RNA1310_5928.1} {RNA815_4314.1} |
2. | MligTC455_44708 | 1291 | 26.9 | Mlig455_063420, Mlig455_066634 | Neo: - Age: - Regeneration-upregulated BL: 1.724 Regeneration-enriched BL: 1.724 |
NDEL1 | 2.577 | - | - | 0.747 | 0.951 | - | 0.879 | Mlig455_063420 {REF} {Length: 2131} {TRANSSPLICED} {Pfam: NUDE protein, C-terminal conserved region [PF04880.15, score=66.1]} {Human: ENSG00000166579, NDEL1, nudE neurodevelopment protein 1 like 1, [RH, Score=192, Expect=2e-57]; ENSG00000275911, NDE1, nudE neurodevelopment protein 1, [RH, Score=186, Expect=4e-55]; ENSG00000072864, NDE1, nudE neurodevelopment protein 1, [RH, Score=186, Expect=4e-55]} {Mouse: ENSMUSG00000018736, Ndel1, nudE neurodevelopment protein 1 like 1, [RH, Score=191, Expect=2e-57]; ENSMUSG00000022678, Nde1, nudE neurodevelopment protein 1, [RH, Score=189, Expect=2e-56]} {Dmel: FBgn0036059, nudE, [RH, Score=114, Expect=2e-28]} {Celegans: WBGene00011230, nud-2, Aspergillus NUclear Division related, [Score=55.8, Expect=1e-08]} {Smed: dd_Smed_v6_1670_0_1, dd_Smed_v6_1670_0_1, [RH, Score=155, Expect=2e-43]} {RNA1509_18131, RNA1509_46395} {RNA1310_12291, RNA1509_18131, RNA1509_46395} {RNA1509_18131, RNA1509_46395, RNA815_21817} Mlig455_066634 {REF} {Length: 2098} {TRANSSPLICED} {Pfam: NUDE protein, C-terminal conserved region [PF04880.15, score=65.8]} {Human: ENSG00000166579, NDEL1, nudE neurodevelopment protein 1 like 1, [RH, Score=193, Expect=6e-58]; ENSG00000275911, NDE1, nudE neurodevelopment protein 1, [RH, Score=186, Expect=3e-55]; ENSG00000072864, NDE1, nudE neurodevelopment protein 1, [RH, Score=186, Expect=3e-55]} {Mouse: ENSMUSG00000018736, Ndel1, nudE neurodevelopment protein 1 like 1, [RH, Score=193, Expect=4e-58]; ENSMUSG00000022678, Nde1, nudE neurodevelopment protein 1, [RH, Score=189, Expect=2e-56]} {Dmel: FBgn0036059, nudE, [RH, Score=115, Expect=6e-29]} {Celegans: WBGene00011230, nud-2, Aspergillus NUclear Division related, [Score=55.8, Expect=1e-08]} {Smed: dd_Smed_v6_1670_0_1, dd_Smed_v6_1670_0_1, [RH, Score=154, Expect=2e-43]} {RNA1509_46395} {RNA1310_12291} {RNA815_21817} |
3. | MligTC455_25901 | 333 | 6.93 | Mlig455_053328, Mlig455_054469 | Neo: - Age: Down-Down-Down |
2.531 | - | - | - | 0.960 | 0.769 | 0.802 | Mlig455_053328 {REF} {Length: 2935} {TRANSSPLICED} {RNA1509_3577} {RNA1310_173.2} {RNA815_485.1} Mlig455_054469 {REF} {Length: 4367} {TRANSSPLICED} {RNA1509_3577} {RNA1310_173.2} {RNA815_485.1} |
|
4. | MligTC455_25902 | 1500 | 31.24 | Mlig455_009504, Mlig455_009544, Mlig455_052770, Mlig455_054087, Mlig455_059396, Mlig455_061235, Mlig455_061748, Mlig455_064501 | Neo: - Age: logFC(26M/2M)=7.524 Regeneration-upregulated BL: 2.245 Regeneration-enriched BL: 2.245 |
2.523 | - | - | - | 0.958 | 0.765 | 0.800 | Mlig455_009504 {REF} {Length: 4614} {TRANSSPLICED} {RNA1509_3577} {RNA1310_173.2} {RNA815_485.1} Mlig455_009544 {REF} {Length: 4612} {TRANSSPLICED} {RNA1509_3577} {RNA1310_173.2} {RNA815_485.1} Mlig455_052770 {REF} {Length: 5275} {TRANSSPLICED} {RNA1509_3577} {RNA1310_173.2} {RNA815_485.1} Mlig455_054087 {REF} {Length: 4537} {TRANSSPLICED} {RNA1509_3577} {RNA1310_173.2} {RNA815_485.1} Mlig455_059396 {REF} {Length: 4612} {TRANSSPLICED} {RNA1509_3577} {RNA1310_173.2} {RNA815_485.1} Mlig455_061235 {REF} {Length: 4612} {TRANSSPLICED} {RNA1509_3577} {RNA1310_173.2} {RNA815_485.1} Mlig455_061748 {REF} {Length: 4612} {TRANSSPLICED} {RNA1509_3577} {RNA1310_173.2} {RNA815_485.1} Mlig455_064501 {REF} {Length: 5178} {TRANSSPLICED} {RNA1509_3577} {RNA1310_173.2} {RNA815_485.1} |
|
5. | MligTC455_25903 | 200 | 4.17 | Mlig455_069664 | Neo: - Age: - |
2.491 | - | - | - | 0.952 | 0.731 | 0.808 | Mlig455_069664 {REF} {Length: 6185} {TRANSSPLICED} {RNA1509_3577} {RNA1310_173.2, RNA1509_3577} {RNA1509_3577, RNA815_485.1} | |
6. | MligTC455_47461 | 351 | 7.31 | Mlig455_059023 | Neo: - Age: - |
KLHDC2 | 1.681 | - | - | - | 0.713 | - | 0.968 | Mlig455_059023 {REF} {Length: 3259} {TRANSSPLICED} {Pfam: Galactose oxidase, central domain [PF13418.8, score=85.8]; Kelch motif [PF13964.8, score=72.1]; Kelch motif [PF13854.8, score=60.0]; Galactose oxidase, central domain [PF13415.8, score=51.1]; Kelch motif [PF07646.17, score=40.8]; Kelch motif [PF01344.27, score=38.8]} {Human: ENSG00000165516, KLHDC2, kelch domain containing 2, [RH, Score=124, Expect=3e-30]} {Mouse: ENSMUSG00000020978, Klhdc2, kelch domain containing 2, [RH, Score=125, Expect=7e-31]} {Dmel: FBgn0040344, CG3711, [Score=62.0, Expect=1e-09]} {Celegans: WBGene00009978, F53E4.1, [Score=59.3, Expect=4e-09]} {Smed: dd_Smed_v6_9892_0_1, dd_Smed_v6_9892_0_1, [RH, Score=96.7, Expect=2e-21]} {RNA1509_12374, RNA1509_47894} {RNA1310_7705.2, RNA1509_12374, RNA1509_47894} {RNA1509_12374, RNA1509_47894, RNA815_5080} |
7. | MligTC455_41730 | 508 | 10.59 | Mlig455_026900 | Neo: - |
0.972 | - | - | - | - | - | 0.972 | Mlig455_026900 {REF} {Length: 2522} {Celegans: WBGene00019479, K07C11.7, UPF0046 protein K07C11.7, [Score=47.4, Expect=1e-05]} {RNA1509_15168} {RNA1310_11530} {RNA815_4956.1} | |
8. | MligTC455_51276 | 83 | 1.74 | Mlig455_014757, Mlig455_014817 | Neo: - Age: Down-Up-Down |
CTGF | 0.963 | - | - | - | - | 0.963 | - | Mlig455_014757 {REF} {Length: 2922} {Pfam: CCN3 Nov like TSP1 domain [PF19035.2, score=54.0]; Insulin-like growth factor binding protein [PF00219.20, score=36.3]; von Willebrand factor type C domain [PF00093.20, score=24.9]} {Human: ENSG00000118523, CTGF, connective tissue growth factor, [RH, Score=191, Expect=6e-57]} {Mouse: ENSMUSG00000019997, Ctgf, connective tissue growth factor, [RH, Score=182, Expect=1e-53]; ENSMUSG00000005124, Wisp1, WNT1 inducible signaling pathway protein 1, [RH, Score=180, Expect=9e-53]; ENSMUSG00000028195, Cyr61, cysteine rich protein 61, [RH, Score=179, Expect=2e-52]} {Dmel: FBgn0052183, Ccn, [RH, Score=73.9, Expect=4e-14]} {Smed: dd_Smed_v6_18465_0_1, dd_Smed_v6_18465_0_1, [RH, Score=152, Expect=2e-42]} {RNA1310_28561} {RNA815_18173} Mlig455_014817 {REF} {Length: 2230} {Pfam: CCN3 Nov like TSP1 domain [PF19035.2, score=54.1]; Insulin-like growth factor binding protein [PF00219.20, score=36.3]; von Willebrand factor type C domain [PF00093.20, score=24.9]} {Human: ENSG00000118523, CTGF, connective tissue growth factor, [RH, Score=189, Expect=3e-56]} {Mouse: ENSMUSG00000019997, Ctgf, connective tissue growth factor, [RH, Score=180, Expect=4e-53]; ENSMUSG00000005124, Wisp1, WNT1 inducible signaling pathway protein 1, [RH, Score=178, Expect=3e-52]; ENSMUSG00000028195, Cyr61, cysteine rich protein 61, [RH, Score=176, Expect=2e-51]} {Dmel: FBgn0052183, Ccn, [RH, Score=74.7, Expect=2e-14]} {Smed: dd_Smed_v6_18465_0_1, dd_Smed_v6_18465_0_1, [RH, Score=150, Expect=5e-42]} {RNA1310_28561} {RNA815_18173} |
9. | MligTC455_22816 | 401 | 8.36 | Mlig455_003071, Mlig455_062819 | Neo: - Age: - Region-enriched R4: 2.851/0.00069 |
FAM57B | 0.962 | - | - | - | 0.962 | - | - | Mlig455_003071 {REF} {Length: 3107} {TRANSSPLICED} {Pfam: TLC domain [PF03798.18, score=86.7]} {Human: ENSG00000149926, FAM57B, family with sequence similarity 57 member B, [RH, Score=119, Expect=7e-32]} {Mouse: ENSMUSG00000058966, Fam57b, family with sequence similarity 57, member B, [RH, Score=124, Expect=6e-34]} {Dmel: FBgn0028480, CG17841, [RH, Score=84.0, Expect=2e-18]} {RNA1509_29800} {RNA1310_20841.2} {RNA815_17082} Mlig455_062819 {REF} {Length: 3492} {TRANSSPLICED} {Pfam: TLC domain [PF03798.18, score=86.0]} {Human: ENSG00000149926, FAM57B, family with sequence similarity 57 member B, [RH, Score=121, Expect=1e-32]} {Mouse: ENSMUSG00000058966, Fam57b, family with sequence similarity 57, member B, [RH, Score=126, Expect=8e-35]} {Dmel: FBgn0028480, CG17841, [RH, Score=82.4, Expect=6e-18]} {RNA1509_29800} {RNA1310_20841.2} {RNA815_17082} |
10. | MligTC455_24232 | 644 | 13.41 | Mlig455_015112 | Neo: - Age: - |
SEC24A | 0.959 | - | - | - | 0.959 | - | - | Mlig455_015112 {REF} {Length: 5092} {TRANSSPLICED} {Pfam: Sec23/Sec24 trunk domain [PF04811.17, score=150.6]; Sec23/Sec24 beta-sandwich domain [PF08033.14, score=67.4]; Sec23/Sec24 helical domain [PF04815.17, score=63.9]; Sec23/Sec24 zinc finger [PF04810.17, score=52.3]; Gelsolin repeat [PF00626.24, score=31.1]} {Human: ENSG00000113615, SEC24A, SEC24 homolog A, COPII coat complex component, [RH, Score=702, Expect=0.0]; ENSG00000138802, SEC24B, SEC24 homolog B, COPII coat complex component, [RH, Score=683, Expect=0.0]} {Mouse: ENSMUSG00000036391, Sec24a, Sec24 related gene family, member A (S. cerevisiae), [RH, Score=707, Expect=0.0]} {Dmel: FBgn0033460, Sec24AB, Secretory 24AB, [RH, Score=652, Expect=0.0]} {Celegans: WBGene00004756, sec-24.2, Yeast SEC homolog, [RH, Score=560, Expect=0.0]} {Smed: dd_Smed_v6_3760_0_1, dd_Smed_v6_3760_0_1, [RH, Score=568, Expect=0.0]} {RNA1509_10942} {RNA1310_4335} {RNA815_5061} |
11. | MligTC455_04286 | 195 | 4.06 | Mlig455_025618 | Neo: - |
MAPKAPK2 | 0.958 | - | - | - | 0.958 | - | - | Mlig455_025618 {REF} {Length: 2172} {Pfam: Protein kinase domain [PF00069.27, score=221.8]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=99.6]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=22.6]; Kinase-like [PF14531.8, score=21.0]} {Human: ENSG00000162889, MAPKAPK2, mitogen-activated protein kinase-activated protein kinase 2, [RH, Score=468, Expect=4e-165]; ENSG00000114738, MAPKAPK3, mitogen-activated protein kinase-activated protein kinase 3, [RH, Score=467, Expect=9e-165]} {Mouse: ENSMUSG00000016528, Mapkapk2, MAP kinase-activated protein kinase 2, [RH, Score=467, Expect=5e-165]; ENSMUSG00000032577, Mapkapk3, mitogen-activated protein kinase-activated protein kinase 3, [RH, Score=465, Expect=3e-164]} {Dmel: FBgn0013987, MAPk-Ak2, MAP kinase activated protein-kinase-2, [RH, Score=455, Expect=1e-160]} {Celegans: WBGene00007007, mak-2, MAP kinase-activated protein kinase mak-2, [RH, Score=412, Expect=5e-144]} {Smed: dd_Smed_v6_1490_0_1, dd_Smed_v6_1490_0_1, [RH, Score=453, Expect=4e-160]} {RNA1509_26630, RNA1509_56091, RNA1509_8157} {RNA1310_13371, RNA1509_26630, RNA1509_56091, RNA1509_8157} {RNA1509_26630, RNA1509_56091, RNA1509_8157, RNA815_4862} |
12. | MligTC455_19365 | 368 | 7.66 | Mlig455_033543 | Neo: - Age: Up-Up-Down |
LMX1A | 0.958 | - | - | - | - | - | 0.958 | Mlig455_033543 {REF} {Length: 3159} {Pfam: LIM domain [PF00412.24, score=80.9]; Homeodomain [PF00046.31, score=23.3]} {Human: ENSG00000162761, LMX1A, LIM homeobox transcription factor 1 alpha, [Score=145, Expect=6e-40]; ENSG00000136944, LMX1B, LIM homeobox transcription factor 1 beta, [Score=145, Expect=3e-40]} {Mouse: ENSMUSG00000038765, Lmx1b, LIM homeobox transcription factor 1 beta, [Score=145, Expect=2e-40]; ENSMUSG00000026686, Lmx1a, LIM homeobox transcription factor 1 alpha, [Score=141, Expect=6e-39]} {Dmel: FBgn0052105, Lmx1a, LIM homeobox transcription factor 1 alpha, [Score=148, Expect=5e-40]} {Celegans: WBGene00002988, lim-6, LIM domain family, [Score=112, Expect=1e-28]} {Smed: dd_Smed_v6_8252_0_1, dd_Smed_v6_8252_0_1, [Score=99.0, Expect=1e-23]} {RNA1509_28203} {RNA1310_17583.1} {RNA815_17757} |
13. | MligTC455_47040 | 498 | 10.38 | Mlig455_057196 | Neo: - Age: - |
FRMD4A | 0.955 | - | - | - | - | - | 0.955 | Mlig455_057196 {REF} {Length: 6173} {TRANSSPLICED} {Pfam: FERM central domain [PF00373.20, score=55.1]; FERM C-terminal PH-like domain [PF09380.12, score=43.3]; FERM N-terminal domain [PF09379.12, score=19.1]} {Human: ENSG00000151474, FRMD4A, FERM domain containing 4A, [RH, Score=219, Expect=5e-58]; ENSG00000114541, FRMD4B, FERM domain containing 4B, [RH, Score=214, Expect=2e-56]} {Mouse: ENSMUSG00000026657, Frmd4a, FERM domain containing 4A, [RH, Score=222, Expect=3e-59]; ENSMUSG00000030064, Frmd4b, FERM domain containing 4B, [RH, Score=218, Expect=5e-58]} {Dmel: FBgn0261985, Ptpmeg, Protein tyrosine phosphatase Meg, [Score=75.5, Expect=2e-13]} {Celegans: WBGene00008555, F07C6.4, [RH, Score=75.1, Expect=2e-13]} {Smed: dd_Smed_v6_2825_0_1, dd_Smed_v6_2825_0_1, [Score=69.3, Expect=9e-12]} {RNA1509_14066} {RNA1310_17543} {RNA815_11394} |
14. | MligTC455_18733 | 252 | 5.25 | Mlig455_005579 | Neo: Int S/G2/M Age: - |
SENP7 | 0.952 | - | - | - | - | - | 0.952 | Mlig455_005579 {REF} {Length: 3096} {TRANSSPLICED} {Pfam: Ulp1 protease family, C-terminal catalytic domain [PF02902.21, score=128.8]} {Human: ENSG00000138468, SENP7, SUMO specific peptidase 7, [Score=203, Expect=8e-54]} {Mouse: ENSMUSG00000052917, Senp7, SUMO1/sentrin specific peptidase 7, [RH, Score=207, Expect=3e-55]} {Dmel: FBgn0035713, velo, veloren, [RH, Score=195, Expect=2e-52]} {Celegans: WBGene00006737, ulp-2, Ubiquitin-like protease 2, [Score=83.6, Expect=2e-16]} {Smed: dd_Smed_v6_11853_0_1, dd_Smed_v6_11853_0_1, [Score=281, Expect=1e-81]} {RNA1509_42487, RNA1509_44335} {RNA1310_5169, RNA1509_42487, RNA1509_44335} {RNA1509_42487, RNA1509_44335, RNA815_2599.1} |