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Results for MligTC455_51185

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_51185 1073 22.36 Mlig455_031371, Mlig455_056513

Neo: -

Age: Up-Down-Down

Region-enriched R5: 1.008/0.01615

PLEKHG1

Mlig455_031371 {REF} {Length: 5976} {TRANSSPLICED} {Pfam: RhoGEF domain [PF00621.22, score=136.8]} {Human: ENSG00000120278, PLEKHG1, pleckstrin homology and RhoGEF domain containing G1, [RH, Score=241, Expect=6e-64]; ENSG00000126822, PLEKHG3, pleckstrin homology and RhoGEF domain containing G3, [RH, Score=237, Expect=4e-63]} {Mouse: ENSMUSG00000052609, Plekhg3, pleckstrin homology domain containing, family G (with RhoGef domain) member 3, [RH, Score=239, Expect=8e-64]} {Dmel: FBgn0050115, GEFmeso, Guanine nucleotide exchange factor in mesoderm, [RH, Score=201, Expect=6e-52]} {Celegans: WBGene00009337, uig-1, UNC-112-Interacting Guanine nucleotide exchange factor, [RH, Score=191, Expect=3e-49]} {Smed: dd_Smed_v6_4803_0_1, dd_Smed_v6_4803_0_1, [RH, Score=186, Expect=1e-48]} {RNA1509_10688} {RNA1310_1913, RNA1509_10688} {RNA1509_10688, RNA815_10599}

Mlig455_056513 {REF} {Length: 5463} {TRANSSPLICED} {Pfam: RhoGEF domain [PF00621.22, score=135.4]} {Human: ENSG00000120278, PLEKHG1, pleckstrin homology and RhoGEF domain containing G1, [RH, Score=234, Expect=6e-62]; ENSG00000126822, PLEKHG3, pleckstrin homology and RhoGEF domain containing G3, [RH, Score=232, Expect=2e-61]} {Mouse: ENSMUSG00000052609, Plekhg3, pleckstrin homology domain containing, family G (with RhoGef domain) member 3, [RH, Score=233, Expect=6e-62]} {Dmel: FBgn0050115, GEFmeso, Guanine nucleotide exchange factor in mesoderm, [RH, Score=200, Expect=1e-51]} {Celegans: WBGene00009337, uig-1, UNC-112-Interacting Guanine nucleotide exchange factor, [RH, Score=187, Expect=2e-48]} {Smed: dd_Smed_v6_4803_0_1, dd_Smed_v6_4803_0_1, [RH, Score=180, Expect=1e-46]} {RNA1509_10688} {RNA1310_1913} {RNA815_10599}

Cumulative graph for MligTC455_51185

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.334 4.777 0.71294 1.00000
RegionR2 0.489 4.777 0.27250 0.65716
RegionR3 -0.845 4.777 0.04201 0.35754
RegionR4 0.19 4.777 0.64772 0.95111
RegionR5 1.008 4.777 0.00180 0.01615
RegionR6 0.26 4.777 0.49279 1.00000
RegionR7 0.712 4.777 0.10685 0.62109
RegionR8 -2.147 4.777 0.01188 0.20917

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -7.833 4.777 0.02865 0.61894
RegenerationR2 0.38 4.777 0.30410 0.74469
RegenerationR3 1.19 4.777 0.00626 0.14311
RegenerationR4 0.182 4.777 0.65952 0.93798
RegenerationR5 0.379 4.777 0.29765 0.72523
RegenerationR6 1.135 4.777 0.00428 0.07858
RegenerationBL 1.601 4.777 0.00087 0.02080
RegenerationTP 0.646 4.777 0.32201 0.76633


Genes with expression patterns similar to MligTC455_51185

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_51185 1073 22.36 Mlig455_031371, Mlig455_056513

Neo: -

Age: Up-Down-Down

Region-enriched R5: 1.008/0.01615

PLEKHG1 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_031371 {REF} {Length: 5976} {TRANSSPLICED} {Pfam: RhoGEF domain [PF00621.22, score=136.8]} {Human: ENSG00000120278, PLEKHG1, pleckstrin homology and RhoGEF domain containing G1, [RH, Score=241, Expect=6e-64]; ENSG00000126822, PLEKHG3, pleckstrin homology and RhoGEF domain containing G3, [RH, Score=237, Expect=4e-63]} {Mouse: ENSMUSG00000052609, Plekhg3, pleckstrin homology domain containing, family G (with RhoGef domain) member 3, [RH, Score=239, Expect=8e-64]} {Dmel: FBgn0050115, GEFmeso, Guanine nucleotide exchange factor in mesoderm, [RH, Score=201, Expect=6e-52]} {Celegans: WBGene00009337, uig-1, UNC-112-Interacting Guanine nucleotide exchange factor, [RH, Score=191, Expect=3e-49]} {Smed: dd_Smed_v6_4803_0_1, dd_Smed_v6_4803_0_1, [RH, Score=186, Expect=1e-48]} {RNA1509_10688} {RNA1310_1913, RNA1509_10688} {RNA1509_10688, RNA815_10599}

Mlig455_056513 {REF} {Length: 5463} {TRANSSPLICED} {Pfam: RhoGEF domain [PF00621.22, score=135.4]} {Human: ENSG00000120278, PLEKHG1, pleckstrin homology and RhoGEF domain containing G1, [RH, Score=234, Expect=6e-62]; ENSG00000126822, PLEKHG3, pleckstrin homology and RhoGEF domain containing G3, [RH, Score=232, Expect=2e-61]} {Mouse: ENSMUSG00000052609, Plekhg3, pleckstrin homology domain containing, family G (with RhoGef domain) member 3, [RH, Score=233, Expect=6e-62]} {Dmel: FBgn0050115, GEFmeso, Guanine nucleotide exchange factor in mesoderm, [RH, Score=200, Expect=1e-51]} {Celegans: WBGene00009337, uig-1, UNC-112-Interacting Guanine nucleotide exchange factor, [RH, Score=187, Expect=2e-48]} {Smed: dd_Smed_v6_4803_0_1, dd_Smed_v6_4803_0_1, [RH, Score=180, Expect=1e-46]} {RNA1509_10688} {RNA1310_1913} {RNA815_10599}
2. MligTC455_24403 293 6.11 Mlig455_002756

Neo: Irradiation

Age: -

ATAD2B 1.863 - - 0.889 - - 0.974 Mlig455_002756 {REF} {Length: 5381} {TRANSSPLICED} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=147.5]; Bromodomain [PF00439.27, score=48.1]; AAA+ lid domain [PF17862.3, score=36.2]; AAA domain (Cdc48 subfamily) [PF07724.16, score=22.9]; AAA ATPase domain [PF13191.8, score=22.0]} {Human: ENSG00000119778, ATAD2B, ATPase family, AAA domain containing 2B, [RH, Score=694, Expect=0.0]} {Mouse: ENSMUSG00000052812, Atad2b, ATPase family, AAA domain containing 2B, [RH, Score=668, Expect=0.0]; ENSMUSG00000116053, Atad2, ATPase family, AAA domain containing 2, [RH, Score=652, Expect=0.0]; ENSMUSG00000022360, Atad2, ATPase family, AAA domain containing 2, [RH, Score=652, Expect=0.0]} {Dmel: FBgn0261014, TER94, [Score=230, Expect=2e-62]} {Celegans: WBGene00008682, lex-1, Tat-binding homolog 7, [RH, Score=513, Expect=5e-160]} {Smed: dd_Smed_v6_8534_0_1, dd_Smed_v6_8534_0_1, [RH, Score=522, Expect=1e-164]} {RNA1509_47976} {RNA1310_2482.1} {RNA815_17171}
3. MligTC455_46964 187 3.89 Mlig455_059229

Neo: Int S/G2/M

Age: -

HINFP 1.786 - - 0.835 - - 0.951 Mlig455_059229 {REF} {Length: 2982} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=28.3]; C2H2-type zinc-finger domain [PF13909.8, score=21.1]; C2H2-type zinc finger [PF13912.8, score=20.8]; C2H2-type zinc finger [PF13894.8, score=20.5]; Zinc-finger double domain [PF13465.8, score=19.6]} {Human: ENSG00000172273, HINFP, histone H4 transcription factor, [RH, Score=181, Expect=6e-50]} {Mouse: ENSMUSG00000032119, Hinfp, histone H4 transcription factor, [RH, Score=179, Expect=2e-50]} {Dmel: FBgn0025635, CG17829, [RH, Score=146, Expect=4e-38]} {Celegans: WBGene00009553, hinf-1, HIstone Nuclear Factor p (P) homolog, [RH, Score=114, Expect=9e-27]} {Smed: dd_Smed_v6_12249_0_1, dd_Smed_v6_12249_0_1, [RH, Score=120, Expect=6e-29]} {RNA1509_18019} {RNA1310_10490, RNA1509_18019} {RNA1509_18019, RNA815_19545}
4. MligTC455_18784 461 9.59 Mlig455_011302, Mlig455_011391

Neo: Int S/G2/M

Age: -

CLIC6 1.768 - - 0.803 - - 0.965

Mlig455_011302 {REF} {Length: 1564} {Human: ENSG00000159212, CLIC6, chloride intracellular channel 6, [Score=61.2, Expect=3e-10]} {RNA1509_15142} {RNA1310_50653} {RNA815_35348}

Mlig455_011391 {REF} {Length: 1551} {Human: ENSG00000159212, CLIC6, chloride intracellular channel 6, [Score=61.2, Expect=3e-10]} {RNA1509_15142} {RNA1310_50653} {RNA815_35348}
5. MligTC455_20536 1039 21.64 Mlig455_023810

Neo: Irradiation

Age: -

CPPED1 1.709 - - 0.750 - - 0.959 Mlig455_023810 {REF} {Length: 1933} {TRANSSPLICED} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=34.7]} {Human: ENSG00000103381, CPPED1, calcineurin like phosphoesterase domain containing 1, [RH, Score=228, Expect=1e-72]} {Mouse: ENSMUSG00000065979, Cpped1, calcineurin-like phosphoesterase domain containing 1, [RH, Score=229, Expect=2e-73]} {Smed: dd_Smed_v6_1690_0_2, dd_Smed_v6_1690_0_2, [RH, Score=233, Expect=2e-75]} {RNA1509_11740} {RNA1310_27956, RNA1509_11740} {RNA1509_11740, RNA815_11890.1}
6. MligTC455_26646 1270 26.47 Mlig455_036193, Mlig455_036200

Neo: Irradiation

Age: -

Region-enriched R4: 2.027/0.00054

Regeneration-downregulated R4: -2.228

Regeneration-depleted R4: -2.228

GIPC3, PTPN23 1.683 - - - 0.967 0.716 -

Mlig455_036193 {REF} {Length: 6626} {Pfam: Protein-tyrosine phosphatase [PF00102.29, score=62.9]} {Human: ENSG00000179855, GIPC3, GIPC PDZ domain containing family member 3, [Score=58.9, Expect=7e-08]} {Mouse: ENSMUSG00000050463, Krt78, keratin 78, [Score=70.9, Expect=1e-11]} {Dmel: FBgn0052656, Muc11A, Mucin 11A, [Score=99.8, Expect=1e-20]} {Celegans: WBGene00021507, Y41D4A.5, Protein-tyrosine-phosphatase, [Score=54.7, Expect=3e-07]} {Smed: dd_Smed_v6_3351_0_2, dd_Smed_v6_3351_0_2, [Score=126, Expect=5e-29]} {RNA1509_13027, RNA1509_26323, RNA1509_55968} {RNA1310_12276.2, RNA1509_13027, RNA1509_26323, RNA1509_55968} {RNA1509_13027, RNA1509_26323, RNA1509_55968, RNA815_6413}

Mlig455_036200 {REF} {Length: 8454} {Pfam: BRO1-like domain [PF03097.20, score=305.8]; ALIX V-shaped domain binding to HIV [PF13949.8, score=96.6]; Protein-tyrosine phosphatase [PF00102.29, score=75.4]} {Human: ENSG00000076201, PTPN23, protein tyrosine phosphatase, non-receptor type 23, [RH, Score=408, Expect=1e-115]} {Mouse: ENSMUSG00000036057, Ptpn23, protein tyrosine phosphatase, non-receptor type 23, [RH, Score=412, Expect=5e-117]} {Dmel: FBgn0036448, mop, myopic, [RH, Score=371, Expect=1e-103]} {Celegans: WBGene00001215, ego-2, Enhancer of Glp-One (Glp-1); Enhancer of glp-1, [RH, Score=260, Expect=1e-69]} {Smed: dd_Smed_v6_3351_0_1, dd_Smed_v6_3351_0_1, [RH, Score=424, Expect=2e-121]} {RNA1509_6410} {RNA1310_2882.1} {RNA815_3253.1}
7. MligTC455_23431 92 1.91 Mlig455_032975

Neo: Int S/G2/M

Age: -

Region-enriched R4: 3.700/0.04652

SUV39H2 0.967 - - - - - 0.967 Mlig455_032975 {REF} {Length: 3806} {Pfam: Septin [PF00735.20, score=287.5]; SET domain [PF00856.30, score=77.6]; Pre-SET motif [PF05033.18, score=57.6]; Chromo (CHRromatin Organisation MOdifier) domain [PF00385.26, score=48.8]; RsgA GTPase [PF03193.18, score=32.0]; 50S ribosome-binding GTPase [PF01926.25, score=27.2]; AAA ATPase domain [PF13191.8, score=25.9]} {Human: ENSG00000152455, SUV39H2, suppressor of variegation 3-9 homolog 2, [RH, Score=269, Expect=6e-81]; ENSG00000101945, SUV39H1, suppressor of variegation 3-9 homolog 1, [RH, Score=265, Expect=2e-79]} {Mouse: ENSMUSG00000026646, Suv39h2, suppressor of variegation 3-9 2, [RH, Score=268, Expect=4e-80]; ENSMUSG00000039231, Suv39h1, suppressor of variegation 3-9 1, [RH, Score=255, Expect=6e-76]} {Dmel: FBgn0011710, Sep1, Septin 1, [Score=247, Expect=1e-73]} {Celegans: WBGene00006795, unc-61, [Score=213, Expect=2e-60]} {Smed: dd_Smed_v6_8819_0_1, dd_Smed_v6_8819_0_1, [RH, Score=328, Expect=9e-103]} {RNA1509_49875} {RNA1310_8346} {RNA815_3453}
8. MligTC455_36608 754 15.7 Mlig455_016801

Neo: Irradiation

Age: -

0.965 - - - - - 0.965 Mlig455_016801 {REF} {Length: 5200} {TRANSSPLICED} {Pfam: Septation ring formation regulator, EzrA [PF06160.14, score=17.7]} {RNA1509_5600} {RNA1310_2454.1} {RNA815_1456}
9. MligTC455_36607 751 15.64 Mlig455_016782

Neo: Irradiation

Age: Down-Up-Up, logFC(26M/2M)=0.309

0.963 - - - - - 0.963 Mlig455_016782 {REF} {Length: 5127} {TRANSSPLICED} {Pfam: Septation ring formation regulator, EzrA [PF06160.14, score=17.7]} {RNA1509_5600} {RNA1310_2454.1} {RNA815_1456}
10. MligTC455_17717 1670 34.79 Mlig455_004373

Neo: Neoblast, stringent

Age: -

Regeneration-enriched BL: 1.714
Regeneration-enriched R6: 1.419

0.958 - - 0.958 - - - Mlig455_004373 {REF} {Length: 4160} {TRANSSPLICED} {RNA1509_10275, RNA1509_13956, RNA1509_14661, RNA1509_23518, RNA1509_26130} {RNA1310_2319.1, RNA1509_10275, RNA1509_13956, RNA1509_14661, RNA1509_23518, RNA1509_26130} {RNA1509_10275, RNA1509_13956, RNA1509_14661, RNA1509_23518, RNA1509_26130, RNA815_4865}
11. MligTC455_51572 930 19.38 Mlig455_042407, Mlig455_042419

Neo: Irradiation

Age: logFC(26M/2M)=0.194

Region-enriched R5: 1.067/0.01680

SMAD2 0.958 - - - - - 0.958

Mlig455_042407 {REF} {Length: 3675} {TRANSSPLICED} {Pfam: MH2 domain [PF03166.16, score=213.5]; MH1 domain [PF03165.18, score=75.5]} {Human: ENSG00000175387, SMAD2, SMAD family member 2, [Score=352, Expect=6e-118]; ENSG00000166949, SMAD3, SMAD family member 3, [Score=348, Expect=2e-116]; ENSG00000170365, SMAD1, SMAD family member 1, [Score=335, Expect=7e-111]} {Mouse: ENSMUSG00000024563, Smad2, SMAD family member 2, [Score=352, Expect=4e-118]; ENSMUSG00000032402, Smad3, SMAD family member 3, [Score=348, Expect=1e-116]; ENSMUSG00000031681, Smad1, SMAD family member 1, [Score=338, Expect=3e-112]; ENSMUSG00000027796, Smad9, SMAD family member 9, [Score=335, Expect=1e-111]} {Dmel: FBgn0011648, Mad, Mothers against dpp, [Score=333, Expect=9e-111]} {Celegans: WBGene00004856, sma-2, Dwarfin sma-2, [Score=234, Expect=8e-73]} {Smed: dd_Smed_v6_6877_0_1, dd_Smed_v6_6877_0_1, [Score=335, Expect=1e-111]} {RNA1509_14402} {RNA1310_10219} {RNA815_6467}

Mlig455_042419 {REF} {Length: 6610} {Pfam: MH2 domain [PF03166.16, score=213.4]; MH1 domain [PF03165.18, score=75.4]} {Human: ENSG00000175387, SMAD2, SMAD family member 2, [Score=350, Expect=5e-117]; ENSG00000166949, SMAD3, SMAD family member 3, [Score=347, Expect=7e-116]; ENSG00000170365, SMAD1, SMAD family member 1, [Score=334, Expect=2e-110]} {Mouse: ENSMUSG00000024563, Smad2, SMAD family member 2, [Score=350, Expect=4e-117]; ENSMUSG00000032402, Smad3, SMAD family member 3, [Score=347, Expect=5e-116]; ENSMUSG00000031681, Smad1, SMAD family member 1, [Score=337, Expect=9e-112]; ENSMUSG00000027796, Smad9, SMAD family member 9, [Score=334, Expect=6e-111]} {Dmel: FBgn0011648, Mad, Mothers against dpp, [Score=333, Expect=3e-110]} {Celegans: WBGene00004856, sma-2, Dwarfin sma-2, [Score=233, Expect=3e-72]} {Smed: dd_Smed_v6_6877_0_1, dd_Smed_v6_6877_0_1, [Score=334, Expect=4e-111]} {RNA1509_14402, RNA1509_29835, RNA1509_53933, RNA1509_58625} {RNA1310_10219, RNA1509_14402, RNA1509_29835, RNA1509_53933, RNA1509_58625} {RNA1509_14402, RNA1509_29835, RNA1509_53933, RNA1509_58625, RNA815_6467}
12. MligTC455_44615 349 7.28 Mlig455_013647

Neo: -

Age: -

Region-enriched R5: 1.203/0.00879

ERG28 0.955 - - - - - 0.955 Mlig455_013647 {REF} {Length: 2311} {TRANSSPLICED} {Pfam: Erg28 like protein [PF03694.15, score=81.5]} {Human: ENSG00000133935, ERG28, ergosterol biosynthesis 28 homolog, [RH, Score=78.6, Expect=1e-18]} {Mouse: ENSMUSG00000021252, Erg28, ergosterol biosynthesis 28, [RH, Score=77.8, Expect=2e-18]} {RNA1509_32376} {RNA1310_30496, RNA1509_32376} {RNA1509_32376, RNA815_19683}
13. MligTC455_49161 139 2.9 Mlig455_062367

Neo: Irradiation

Age: -

0.95 - - - - - 0.950 Mlig455_062367 {REF} {Length: 4268} {TRANSSPLICED} {Pfam: Phytochelatin synthase [PF05023.16, score=275.1]} {Celegans: WBGene00003960, pcs-1, PhytoChelatin Synthase, [RH, Score=244, Expect=3e-75]} {Smed: dd_Smed_v6_11700_0_1, dd_Smed_v6_11700_0_1, [RH, Score=300, Expect=1e-96]} {RNA1509_31673} {RNA1310_2142} {RNA815_14799}

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