M. lignano Tomo-Seq
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Results for MligTC455_51423

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_51423 3614 75.28 Mlig455_021901

Neo: -

Age: -

Regeneration-downregulated R2: -1.093

Regeneration-depleted R2: -1.093

 CALM2 Mlig455_021901 {REF} {Length: 2189} {TRANSSPLICED} {Pfam: EF hand [PF00036.34, score=141.5]; EF-hand domain pair [PF13499.8, score=125.9]; EF-hand domain pair [PF13833.8, score=108.2]; EF-hand domain [PF13405.8, score=98.7]; EF hand [PF13202.8, score=95.3]; EF-hand domain [PF14658.8, score=61.9]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=40.9]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=32.1]; EF-hand domain [PF08976.13, score=28.8]; Uncharacterised protein family (UPF0154) [PF03672.15, score=23.7]; Ca2+ insensitive EF hand [PF08726.12, score=21.4]; Dockerin type I domain [PF00404.20, score=21.1]; Caleosin related protein [PF05042.15, score=18.8]; Repeat of unknown function (DUF1103) [PF06513.13, score=18.5]} {Human: ENSG00000143933, CALM2, calmodulin 2, [RH, Score=295, Expect=2e-103]; ENSG00000198668, CALM1, calmodulin 1, [RH, Score=293, Expect=2e-103]; ENSG00000160014, CALM3, calmodulin 3, [RH, Score=291, Expect=2e-102]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [RH, Score=291, Expect=1e-102]; ENSMUSG00000036438, Calm2, calmodulin 2, [RH, Score=291, Expect=1e-102]; ENSMUSG00000001175, Calm1, calmodulin 1, [RH, Score=291, Expect=1e-102]} {Dmel: FBgn0000253, Cam, Calmodulin, [RH, Score=294, Expect=4e-104]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [RH, Score=295, Expect=1e-104]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [RH, Score=295, Expect=8e-105]} {RNA1509_10228} {RNA1310_22130} {RNA815_4214.1}

Cumulative graph for MligTC455_51423

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.562 6.291 0.25699 0.90496
RegionR2 0.437 6.291 0.09127 0.37086
RegionR3 -0.495 6.291 0.03183 0.30835
RegionR4 -0.026 6.291 0.92459 1.00000
RegionR5 0.139 6.291 0.51933 0.88217
RegionR6 0.146 6.291 0.51855 1.00000
RegionR7 -0.081 6.291 0.75464 1.00000
RegionR8 0.443 6.291 0.12661 0.65425

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.152 6.291 0.13321 0.86812
RegenerationR2 -1.093 6.291 0.00003 0.00621 Specific for R2: -1.093
RegenerationR3 -0.427 6.291 0.13371 0.55712
RegenerationR4 -0.708 6.291 0.01434 0.18751
RegenerationR5 -0.884 6.291 0.00116 0.05645
RegenerationR6 -0.674 6.291 0.01643 0.15833
RegenerationBL -0.536 6.291 0.05420 0.26937
RegenerationTP -0.845 6.291 0.00515 0.12062


Genes with expression patterns similar to MligTC455_51423

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_51423 3614 75.28 Mlig455_021901

Neo: -

Age: -

Regeneration-downregulated R2: -1.093

Regeneration-depleted R2: -1.093

 CALM2 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_021901 {REF} {Length: 2189} {TRANSSPLICED} {Pfam: EF hand [PF00036.34, score=141.5]; EF-hand domain pair [PF13499.8, score=125.9]; EF-hand domain pair [PF13833.8, score=108.2]; EF-hand domain [PF13405.8, score=98.7]; EF hand [PF13202.8, score=95.3]; EF-hand domain [PF14658.8, score=61.9]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=40.9]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=32.1]; EF-hand domain [PF08976.13, score=28.8]; Uncharacterised protein family (UPF0154) [PF03672.15, score=23.7]; Ca2+ insensitive EF hand [PF08726.12, score=21.4]; Dockerin type I domain [PF00404.20, score=21.1]; Caleosin related protein [PF05042.15, score=18.8]; Repeat of unknown function (DUF1103) [PF06513.13, score=18.5]} {Human: ENSG00000143933, CALM2, calmodulin 2, [RH, Score=295, Expect=2e-103]; ENSG00000198668, CALM1, calmodulin 1, [RH, Score=293, Expect=2e-103]; ENSG00000160014, CALM3, calmodulin 3, [RH, Score=291, Expect=2e-102]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [RH, Score=291, Expect=1e-102]; ENSMUSG00000036438, Calm2, calmodulin 2, [RH, Score=291, Expect=1e-102]; ENSMUSG00000001175, Calm1, calmodulin 1, [RH, Score=291, Expect=1e-102]} {Dmel: FBgn0000253, Cam, Calmodulin, [RH, Score=294, Expect=4e-104]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [RH, Score=295, Expect=1e-104]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [RH, Score=295, Expect=8e-105]} {RNA1509_10228} {RNA1310_22130} {RNA815_4214.1}
2. MligTC455_51424 3418 71.21 Mlig455_021978

Neo: -

Age: -

Regeneration-downregulated R2: -1.182

Regeneration-depleted R2: -1.182

 CALM2 5.923 0.997 0.999 0.997 0.991 0.981 0.958 Mlig455_021978 {REF} {Length: 2208} {TRANSSPLICED} {Pfam: EF hand [PF00036.34, score=141.5]; EF-hand domain pair [PF13499.8, score=125.9]; EF-hand domain pair [PF13833.8, score=108.2]; EF-hand domain [PF13405.8, score=98.7]; EF hand [PF13202.8, score=95.3]; EF-hand domain [PF14658.8, score=61.9]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=40.9]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=32.1]; EF-hand domain [PF08976.13, score=28.8]; Uncharacterised protein family (UPF0154) [PF03672.15, score=23.7]; Ca2+ insensitive EF hand [PF08726.12, score=21.4]; Dockerin type I domain [PF00404.20, score=21.1]; Caleosin related protein [PF05042.15, score=18.8]; Repeat of unknown function (DUF1103) [PF06513.13, score=18.5]} {Human: ENSG00000143933, CALM2, calmodulin 2, [RH, Score=295, Expect=2e-103]; ENSG00000198668, CALM1, calmodulin 1, [RH, Score=293, Expect=2e-103]; ENSG00000160014, CALM3, calmodulin 3, [RH, Score=291, Expect=2e-102]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [RH, Score=291, Expect=1e-102]; ENSMUSG00000036438, Calm2, calmodulin 2, [RH, Score=291, Expect=1e-102]; ENSMUSG00000001175, Calm1, calmodulin 1, [RH, Score=291, Expect=1e-102]} {Dmel: FBgn0000253, Cam, Calmodulin, [RH, Score=294, Expect=4e-104]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [RH, Score=295, Expect=1e-104]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [RH, Score=295, Expect=8e-105]} {RNA1509_10228, RNA1509_14586, RNA1509_22968} {RNA1310_22130, RNA1509_10228, RNA1509_14586, RNA1509_22968} {RNA1509_10228, RNA1509_14586, RNA1509_22968, RNA815_4214.1}
3. MligTC455_39791 985 20.51 Mlig455_053858, Mlig455_053873

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.652

 0.974 - - - - 0.974 -

Mlig455_053858 {REF} {Length: 1795} {Pfam: Transcription factor IIA, alpha/beta subunit [PF03153.15, score=21.3]} {RNA1509_14701} {RNA1310_21415, RNA1509_14701} {RNA1509_14701, RNA815_13655.1}

Mlig455_053873 {REF} {Length: 1679} {RNA1509_14701} {RNA1310_21415} {RNA815_13655.1}
4. MligTC455_27814 1123 23.4 Mlig455_000431, Mlig455_025465, Mlig455_026673, Mlig455_031368, Mlig455_038310, Mlig455_064148, Mlig455_066134

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.823

Regeneration-upregulated BL: 2.840

Regeneration-enriched BL: 2.840

 0.955 - - - 0.955 - -

Mlig455_000431 {REF} {Length: 7484} {RNA1509_16349, RNA1509_55826} {RNA1310_1311.1, RNA1509_16349, RNA1509_55826} {RNA1509_16349, RNA1509_55826, RNA815_19414}

Mlig455_025465 {REF} {Length: 2972} {RNA1509_8341} {RNA1310_843} {RNA815_1305.1}

Mlig455_026673 {REF} {Length: 758} {RNA1509_8341} {RNA1310_50077} {RNA815_2170.1}

Mlig455_031368 {REF} {Length: 392} {NoTransDecoderORF} {RNA1509_13206} {RNA1310_1311.1} {RNA815_19414}

Mlig455_038310 {REF} {Length: 963} {RNA1509_8341} {RNA1310_50077} {RNA815_2170.1}

Mlig455_064148 {REF} {Length: 5448} {TRANSSPLICED} {RNA1509_8946} {RNA1310_3396.1} {RNA815_1342.1}

Mlig455_066134 {REF} {Length: 3326} {RNA1509_8341} {RNA1310_843, RNA1509_8341} {RNA1509_8341, RNA815_2170.1}

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