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Results for MligTC455_51597

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_51597 1321 27.52 Mlig455_014868, Mlig455_014909, Mlig455_014993

Neo: -

Age: -

Region-enriched R3: 3.740/0.00000
Region-enriched R5: 2.963/0.00013
Region-enriched R6: 2.888/0.00494

SLC16A12

Mlig455_014868 {REF} {Length: 5090} {Pfam: Major Facilitator Superfamily [PF07690.18, score=59.2]; Dynamin family [PF00350.25, score=28.1]; 50S ribosome-binding GTPase [PF01926.25, score=28.0]; Elongation factor Tu GTP binding domain [PF00009.29, score=25.7]; Protein kinase domain [PF00069.27, score=23.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=20.9]; FtsK/SpoIIIE family [PF01580.20, score=18.7]} {Human: ENSG00000152779, SLC16A12, solute carrier family 16 member 12, [Score=51.2, Expect=1e-05]} {Mouse: ENSMUSG00000045775, Slc16a5, solute carrier family 16 (monocarboxylic acid transporters), member 5, [Score=57.4, Expect=8e-08]} {Dmel: FBgn0033028, CG11665, [Score=63.5, Expect=1e-09]} {Smed: dd_Smed_v6_1284_0_1, dd_Smed_v6_1284_0_1, [RH, Score=514, Expect=4e-170]} {RNA1509_9414} {RNA1310_4109.2} {RNA815_1086}

Mlig455_014909 {REF} {Length: 3678} {Pfam: 50S ribosome-binding GTPase [PF01926.25, score=29.1]; Dynamin family [PF00350.25, score=28.2]; Protein kinase domain [PF00069.27, score=27.5]; Elongation factor Tu GTP binding domain [PF00009.29, score=25.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=23.9]; FtsK/SpoIIIE family [PF01580.20, score=18.9]} {Celegans: WBGene00013355, gck-3, Germinal center kinase 3, [Score=48.9, Expect=1e-05]} {Smed: dd_Smed_v6_7028_0_1, dd_Smed_v6_7028_0_1, [Score=60.1, Expect=5e-09]} {RNA1509_9414} {RNA1310_4109.2} {RNA815_1086}

Mlig455_014993 {REF} {Length: 4883} {Pfam: Major Facilitator Superfamily [PF07690.18, score=59.2]; Dynamin family [PF00350.25, score=28.1]; 50S ribosome-binding GTPase [PF01926.25, score=28.1]; Protein kinase domain [PF00069.27, score=25.6]; Elongation factor Tu GTP binding domain [PF00009.29, score=25.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=22.7]; FtsK/SpoIIIE family [PF01580.20, score=19.4]} {Human: ENSG00000152779, SLC16A12, solute carrier family 16 member 12, [Score=51.2, Expect=1e-05]} {Mouse: ENSMUSG00000045775, Slc16a5, solute carrier family 16 (monocarboxylic acid transporters), member 5, [Score=57.4, Expect=9e-08]} {Dmel: FBgn0033028, CG11665, [Score=63.5, Expect=9e-10]} {Smed: dd_Smed_v6_1284_0_1, dd_Smed_v6_1284_0_1, [RH, Score=515, Expect=2e-170]} {RNA1509_9414} {RNA1310_4109.2} {RNA815_1086}

Cumulative graph for MligTC455_51597

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -8.71 4.838 0.00531 0.22777
RegionR2 1.075 4.838 0.32303 0.71530
RegionR3 3.74 4.838 0.00000 0.00000
RegionR4 1.733 4.838 0.03244 0.14364
RegionR5 2.963 4.838 0.00000 0.00013
RegionR6 2.888 4.838 0.00006 0.00494
RegionR7 -2.127 4.838 0.99958 1.00000
RegionR8 -1.563 4.838 0.99691 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 10.357 4.838 0.00007 0.04389
RegenerationR2 1.403 4.838 0.02985 0.28416
RegenerationR3 0.187 4.838 0.74818 0.96399
RegenerationR4 1.134 4.838 0.07359 0.43087
RegenerationR5 0.338 4.838 0.56434 0.89368
RegenerationR6 0.631 4.838 0.29327 0.64395
RegenerationBL 2.398 4.838 0.00199 0.03603
RegenerationTP 2.133 4.838 0.05244 0.37464


Genes with expression patterns similar to MligTC455_51597

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_51597 1321 27.52 Mlig455_014868, Mlig455_014909, Mlig455_014993

Neo: -

Age: -

Region-enriched R3: 3.740/0.00000
Region-enriched R5: 2.963/0.00013
Region-enriched R6: 2.888/0.00494

SLC16A12 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_014868 {REF} {Length: 5090} {Pfam: Major Facilitator Superfamily [PF07690.18, score=59.2]; Dynamin family [PF00350.25, score=28.1]; 50S ribosome-binding GTPase [PF01926.25, score=28.0]; Elongation factor Tu GTP binding domain [PF00009.29, score=25.7]; Protein kinase domain [PF00069.27, score=23.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=20.9]; FtsK/SpoIIIE family [PF01580.20, score=18.7]} {Human: ENSG00000152779, SLC16A12, solute carrier family 16 member 12, [Score=51.2, Expect=1e-05]} {Mouse: ENSMUSG00000045775, Slc16a5, solute carrier family 16 (monocarboxylic acid transporters), member 5, [Score=57.4, Expect=8e-08]} {Dmel: FBgn0033028, CG11665, [Score=63.5, Expect=1e-09]} {Smed: dd_Smed_v6_1284_0_1, dd_Smed_v6_1284_0_1, [RH, Score=514, Expect=4e-170]} {RNA1509_9414} {RNA1310_4109.2} {RNA815_1086}

Mlig455_014909 {REF} {Length: 3678} {Pfam: 50S ribosome-binding GTPase [PF01926.25, score=29.1]; Dynamin family [PF00350.25, score=28.2]; Protein kinase domain [PF00069.27, score=27.5]; Elongation factor Tu GTP binding domain [PF00009.29, score=25.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=23.9]; FtsK/SpoIIIE family [PF01580.20, score=18.9]} {Celegans: WBGene00013355, gck-3, Germinal center kinase 3, [Score=48.9, Expect=1e-05]} {Smed: dd_Smed_v6_7028_0_1, dd_Smed_v6_7028_0_1, [Score=60.1, Expect=5e-09]} {RNA1509_9414} {RNA1310_4109.2} {RNA815_1086}

Mlig455_014993 {REF} {Length: 4883} {Pfam: Major Facilitator Superfamily [PF07690.18, score=59.2]; Dynamin family [PF00350.25, score=28.1]; 50S ribosome-binding GTPase [PF01926.25, score=28.1]; Protein kinase domain [PF00069.27, score=25.6]; Elongation factor Tu GTP binding domain [PF00009.29, score=25.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=22.7]; FtsK/SpoIIIE family [PF01580.20, score=19.4]} {Human: ENSG00000152779, SLC16A12, solute carrier family 16 member 12, [Score=51.2, Expect=1e-05]} {Mouse: ENSMUSG00000045775, Slc16a5, solute carrier family 16 (monocarboxylic acid transporters), member 5, [Score=57.4, Expect=9e-08]} {Dmel: FBgn0033028, CG11665, [Score=63.5, Expect=9e-10]} {Smed: dd_Smed_v6_1284_0_1, dd_Smed_v6_1284_0_1, [RH, Score=515, Expect=2e-170]} {RNA1509_9414} {RNA1310_4109.2} {RNA815_1086}
2. MligTC455_24112 7326 152.63 Mlig455_006637, Mlig455_070643

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.380

CYP2D6, CYP2U1 3.477 0.768 - 0.873 0.969 0.867 -

Mlig455_006637 {REF} {Length: 1777} {Pfam: Cytochrome P450 [PF00067.24, score=343.6]} {Human: ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=263, Expect=7e-81]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [RH, Score=263, Expect=2e-81]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [RH, Score=260, Expect=2e-80]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [RH, Score=259, Expect=4e-80]; ENSG00000275211, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=2e-79]; ENSG00000283284, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=1e-79]; ENSG00000100197, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=3e-79]; ENSG00000280905, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]; ENSG00000272532, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]; ENSG00000272000, AC236040.1, cytochrome P450 family 2 subfamily D member 6 pseudogene, [RH, Score=257, Expect=4e-79]; ENSG00000282966, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]} {Mouse: ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=285, Expect=3e-90]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [RH, Score=283, Expect=1e-89]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=278, Expect=2e-87]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=273, Expect=2e-85]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=271, Expect=8e-85]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=271, Expect=1e-84]} {Dmel: FBgn0001992, Cyp303a1, [RH, Score=207, Expect=1e-60]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [RH, Score=292, Expect=3e-93]} {RNA1509_10420} {RNA1310_15091.1} {RNA815_4606.2}

Mlig455_070643 {REF} {Length: 2371} {Pfam: Cytochrome P450 [PF00067.24, score=337.1]} {Human: ENSG00000283284, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=261, Expect=1e-80]; ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=260, Expect=7e-80]; ENSG00000275211, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=260, Expect=2e-80]; ENSG00000282966, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000272000, AC236040.1, cytochrome P450 family 2 subfamily D member 6 pseudogene, [RH, Score=259, Expect=3e-80]; ENSG00000272532, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000280905, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000100197, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [RH, Score=256, Expect=6e-79]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [RH, Score=254, Expect=3e-78]} {Mouse: ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=280, Expect=2e-88]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [RH, Score=279, Expect=7e-88]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=275, Expect=3e-86]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=268, Expect=1e-83]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=268, Expect=1e-83]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=266, Expect=7e-83]} {Dmel: FBgn0001992, Cyp303a1, [RH, Score=201, Expect=4e-58]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [RH, Score=288, Expect=2e-91]} {RNA1509_10420, RNA1509_36519} {RNA1310_15091.1, RNA1509_10420, RNA1509_36519} {RNA1509_10420, RNA1509_36519, RNA815_4606.2}
3. MligTC455_41353 2795 58.23 Mlig455_009229, Mlig455_037082

Neo: -

Age: Down-Up-Down

Region-enriched R4: 1.763/0.00008
Region-enriched R3: 1.061/0.01413

MOGAT2 3.393 0.799 0.823 - 0.953 0.818 -

Mlig455_009229 {REF} {Length: 1921} {Pfam: Diacylglycerol acyltransferase [PF03982.15, score=329.5]} {Human: ENSG00000166391, MOGAT2, monoacylglycerol O-acyltransferase 2, [Score=294, Expect=4e-98]} {Mouse: ENSMUSG00000052396, Mogat2, monoacylglycerol O-acyltransferase 2, [Score=288, Expect=3e-96]; ENSMUSG00000012187, Mogat1, monoacylglycerol O-acyltransferase 1, [Score=280, Expect=4e-93]} {Dmel: FBgn0033215, CG1942, [Score=189, Expect=2e-57]} {Celegans: WBGene00010296, dgat-2, Acyl-CoA:DiacylGlycerol AcylTransferase, [Score=250, Expect=3e-81]} {Smed: dd_Smed_v6_4947_0_1, dd_Smed_v6_4947_0_1, [Score=258, Expect=2e-84]} {RNA1509_31303} {RNA1310_20300} {RNA815_11687.1}

Mlig455_037082 {REF} {Length: 1913} {Pfam: Diacylglycerol acyltransferase [PF03982.15, score=329.5]} {Human: ENSG00000166391, MOGAT2, monoacylglycerol O-acyltransferase 2, [Score=294, Expect=4e-98]} {Mouse: ENSMUSG00000052396, Mogat2, monoacylglycerol O-acyltransferase 2, [Score=288, Expect=3e-96]; ENSMUSG00000012187, Mogat1, monoacylglycerol O-acyltransferase 1, [Score=280, Expect=4e-93]} {Dmel: FBgn0033215, CG1942, [Score=189, Expect=2e-57]} {Celegans: WBGene00010296, dgat-2, Acyl-CoA:DiacylGlycerol AcylTransferase, [Score=250, Expect=3e-81]} {Smed: dd_Smed_v6_4947_0_1, dd_Smed_v6_4947_0_1, [Score=258, Expect=2e-84]} {RNA1509_20138, RNA1509_20368, RNA1509_23468, RNA1509_31303, RNA1509_57229} {RNA1310_20300, RNA1509_20138, RNA1509_20368, RNA1509_23468, RNA1509_31303, RNA1509_57229} {RNA1509_20138, RNA1509_20368, RNA1509_23468, RNA1509_31303, RNA1509_57229, RNA815_11687.1}
4. MligTC455_18724 1612 33.59 Mlig455_037198

Neo: -

Age: -

Region-enriched R3: 2.022/0.00141

SLC3A1 3.338 - 0.706 0.775 0.959 0.898 - Mlig455_037198 {REF} {Length: 2052} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=311.9]} {Human: ENSG00000138079, SLC3A1, solute carrier family 3 member 1, [RH, Score=373, Expect=2e-120]} {Mouse: ENSMUSG00000024131, Slc3a1, solute carrier family 3, member 1, [RH, Score=374, Expect=5e-121]} {Dmel: FBgn0002570, Mal-A1, Maltase A1, [RH, Score=385, Expect=1e-126]} {Celegans: WBGene00000225, atgp-2, Amino acid Transporter GlycoProtein subunit, [RH, Score=147, Expect=2e-37]} {Smed: dd_Smed_v6_2113_0_1, dd_Smed_v6_2113_0_1, [Score=67.8, Expect=9e-12]} {RNA1509_14094, RNA1509_15182, RNA1509_19345} {RNA1310_12682.1, RNA1509_14094, RNA1509_15182, RNA1509_19345} {RNA1509_14094, RNA1509_15182, RNA1509_19345, RNA815_15968}
5. MligTC455_18723 1597 33.27 Mlig455_004384

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.781

Region-enriched R3: 2.164/0.00079
Region-enriched R4: 1.576/0.04930
Region-enriched R5: 1.329/0.03977

SLC3A1 3.334 - 0.707 0.775 0.961 0.891 - Mlig455_004384 {REF} {Length: 2040} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=310.6]} {Human: ENSG00000138079, SLC3A1, solute carrier family 3 member 1, [RH, Score=371, Expect=2e-119]} {Mouse: ENSMUSG00000024131, Slc3a1, solute carrier family 3, member 1, [RH, Score=372, Expect=4e-120]} {Dmel: FBgn0002570, Mal-A1, Maltase A1, [RH, Score=384, Expect=2e-126]} {Celegans: WBGene00000224, atgp-1, Amino acid Transporter GlycoProtein subunit, [RH, Score=146, Expect=3e-37]} {Smed: dd_Smed_v6_2113_0_1, dd_Smed_v6_2113_0_1, [Score=67.8, Expect=8e-12]} {RNA1509_19345} {RNA1310_12682.1} {RNA815_15968}
6. MligTC455_41352 1305 27.18 Mlig455_037071

Neo: -

Age: Up-Down-Up

Region-enriched R4: 1.918/0.00007
Region-enriched R3: 1.036/0.03342

MOGAT2 3.314 0.744 0.802 - 0.956 0.812 - Mlig455_037071 {REF} {Length: 866} {Pfam: Diacylglycerol acyltransferase [PF03982.15, score=209.7]} {Human: ENSG00000166391, MOGAT2, monoacylglycerol O-acyltransferase 2, [Score=189, Expect=9e-60]} {Mouse: ENSMUSG00000052396, Mogat2, monoacylglycerol O-acyltransferase 2, [Score=184, Expect=8e-57]} {Dmel: FBgn0033215, CG1942, [Score=154, Expect=4e-45]} {Celegans: WBGene00019464, K07B1.4, [Score=172, Expect=3e-52]} {Smed: dd_Smed_v6_4947_0_1, dd_Smed_v6_4947_0_1, [Score=154, Expect=1e-45]} {RNA1509_20138} {RNA1310_22626} {RNA815_11687.1}
7. MligTC455_53810 10368 216.01 Mlig455_015254

Neo: -

Age: logFC(26M/2M)=-0.519

Region-enriched R3: 1.584/0.00569
Region-enriched R5: 1.232/0.02515

SULT1C4 3.303 - 0.771 0.724 0.950 0.858 - Mlig455_015254 {REF} {Length: 3712} {Pfam: Sulfotransferase domain [PF00685.29, score=172.2]; Sulfotransferase family [PF13469.8, score=31.5]} {Human: ENSG00000198075, SULT1C4, sulfotransferase family 1C member 4, [Score=168, Expect=6e-50]; ENSG00000198203, SULT1C2, sulfotransferase family 1C member 2, [Score=167, Expect=7e-50]} {Mouse: ENSMUSG00000023122, Sult1c2, sulfotransferase family, cytosolic, 1C, member 2, [Score=163, Expect=3e-48]} {Dmel: FBgn0034887, St1, Sulfotransferase 1, [Score=111, Expect=2e-28]} {Celegans: WBGene00013748, ssu-1, Suppressor of Stomatin mutant Uncoordination, [Score=99.0, Expect=2e-23]} {Smed: dd_Smed_v6_4622_0_1, dd_Smed_v6_4622_0_1, [Score=152, Expect=1e-44]} {RNA1509_178, RNA1509_182} {RNA1310_14124, RNA1509_178, RNA1509_182} {RNA1509_178, RNA1509_182, RNA815_6793}
8. MligTC455_20726 1772 36.91 Mlig455_035274

Neo: -

Age: -

Region-enriched R3: 2.119/0.00009

SLC1A6 3.247 - 0.728 - 0.971 0.790 0.758 Mlig455_035274 {REF} {Length: 2086} {Pfam: Sodium:dicarboxylate symporter family [PF00375.20, score=422.3]} {Human: ENSG00000105143, SLC1A6, solute carrier family 1 member 6, [RH, Score=462, Expect=9e-158]} {Mouse: ENSMUSG00000024935, Slc1a1, solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1, [RH, Score=457, Expect=3e-156]; ENSMUSG00000005357, Slc1a6, solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6, [RH, Score=452, Expect=6e-154]} {Dmel: FBgn0026439, Eaat1, Excitatory amino acid transporter 1, [RH, Score=373, Expect=4e-124]} {Celegans: WBGene00001620, glt-1, Excitatory amino acid transporter, [Score=421, Expect=6e-143]} {Smed: dd_Smed_v6_1106_0_1, dd_Smed_v6_1106_0_1, [Score=427, Expect=2e-145]} {RNA1509_5272, RNA1509_57758, RNA1509_7401} {RNA1310_8553.1, RNA1509_5272, RNA1509_57758} {RNA1509_5272, RNA1509_57758, RNA815_2974.1}
9. MligTC455_35337 5019 104.55 Mlig455_003928

Neo: -

Age: -

Region-enriched R6: 1.841/0.00452

CPT1A 3.112 - 0.704 0.719 0.960 0.729 - Mlig455_003928 {REF} {Length: 2596} {TRANSSPLICED} {Pfam: Choline/Carnitine o-acyltransferase [PF00755.22, score=588.5]; Carnitine O-palmitoyltransferase N-terminus [PF16484.7, score=61.5]} {Human: ENSG00000110090, CPT1A, carnitine palmitoyltransferase 1A, [RH, Score=825, Expect=0.0]; ENSG00000205560, CPT1B, carnitine palmitoyltransferase 1B, [RH, Score=822, Expect=0.0]} {Mouse: ENSMUSG00000078937, Cpt1b, carnitine palmitoyltransferase 1b, muscle, [RH, Score=817, Expect=0.0]; ENSMUSG00000024900, Cpt1a, carnitine palmitoyltransferase 1a, liver, [RH, Score=810, Expect=0.0]} {Dmel: FBgn0261862, whd, withered, [RH, Score=802, Expect=0.0]} {Celegans: WBGene00012907, cpt-1, Carnitine Palmitoyl Transferase, [RH, Score=711, Expect=0.0]} {Smed: dd_Smed_v6_4901_0_1, dd_Smed_v6_4901_0_1, [RH, Score=818, Expect=0.0]} {RNA1509_18863, RNA1509_21032, RNA1509_2666, RNA1509_35613, RNA1509_46276, RNA1509_5678} {RNA1310_6310.1, RNA1509_18863, RNA1509_21032, RNA1509_2666, RNA1509_35613, RNA1509_46276, RNA1509_5678} {RNA1509_18863, RNA1509_21032, RNA1509_2666, RNA1509_35613, RNA1509_46276, RNA1509_5678, RNA815_1995.1}
10. MligTC455_46978 301 6.28 Mlig455_054860

Neo: -

Age: -

Region-enriched R3: 2.613/0.01524

2.697 - - 0.779 0.932 - 0.986 Mlig455_054860 {REF} {Length: 3229} {Pfam: Low-density lipoprotein receptor domain class A [PF00057.20, score=47.0]} {Mouse: ENSMUSG00000024924, Vldlr, very low density lipoprotein receptor, [Score=45.4, Expect=9e-06]} {Celegans: WBGene00003071, lrp-1, Low-density lipoprotein receptor-related protein, [Score=49.7, Expect=1e-05]} {RNA1509_30704, RNA1509_39103, RNA1509_40075} {RNA1310_2479.1, RNA1509_30704, RNA1509_39103, RNA1509_40075} {RNA1509_30704, RNA1509_39103, RNA1509_40075, RNA815_5629.1}
11. MligTC455_40293 973 20.27 Mlig455_003116

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.598

Region-enriched R4: 2.611/0.00000
Region-enriched R3: 1.603/0.00240
Region-enriched R5: 1.400/0.00374

VAV1 2.686 - 0.864 - 0.969 0.853 - Mlig455_003116 {REF} {Length: 5727} {Pfam: SH2 domain [PF00017.26, score=32.8]; RhoGEF domain [PF00621.22, score=31.4]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=27.4]} {Human: ENSG00000141968, VAV1, vav guanine nucleotide exchange factor 1, [Score=95.1, Expect=2e-19]} {Mouse: ENSMUSG00000034116, Vav1, vav 1 oncogene, [Score=92.0, Expect=1e-18]} {Dmel: FBgn0040068, Vav, Vav guanine nucleotide exchange factor, [Score=65.1, Expect=2e-10]} {Celegans: WBGene00006887, vav-1, [Score=65.5, Expect=9e-11]} {RNA1509_11835} {RNA1310_8757} {RNA815_2576}
12. MligTC455_34732 132 2.75 Mlig455_070049

Neo: -

Age: -

XDH 2.68 - - - 0.872 0.815 0.993 Mlig455_070049 {REF} {Length: 4638} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=575.7]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=160.0]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=99.9]; [2Fe-2S] binding domain [PF01799.22, score=96.2]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=82.2]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=28.6]} {Human: ENSG00000158125, XDH, xanthine dehydrogenase, [Score=1130, Expect=0.0]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=1122, Expect=0.0]} {Dmel: FBgn0003308, ry, rosy, [Score=1143, Expect=0.0]} {Celegans: WBGene00010083, xhd-1, [RH, Score=1056, Expect=0.0]} {RNA1509_15799} {RNA1310_2743} {RNA815_28439}
13. MligTC455_40294 928 19.33 Mlig455_062769

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.415

Region-enriched R4: 2.693/0.00000
Region-enriched R3: 1.531/0.00694
Region-enriched R5: 1.366/0.00671

VAV1 2.648 - 0.850 - 0.963 0.835 - Mlig455_062769 {REF} {Length: 4319} {Pfam: SH2 domain [PF00017.26, score=34.9]; RhoGEF domain [PF00621.22, score=28.2]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=27.1]} {Human: ENSG00000141968, VAV1, vav guanine nucleotide exchange factor 1, [Score=93.6, Expect=5e-19]} {Mouse: ENSMUSG00000034116, Vav1, vav 1 oncogene, [Score=91.3, Expect=1e-18]} {Dmel: FBgn0040068, Vav, Vav guanine nucleotide exchange factor, [Score=61.2, Expect=2e-09]} {Celegans: WBGene00006887, vav-1, [Score=64.3, Expect=2e-10]} {RNA1509_11835} {RNA1310_8757} {RNA815_2576}
14. MligTC455_46736 403 8.4 Mlig455_064968, Mlig455_066818

Neo: -

Age: -

Region-enriched R4: 2.255/0.01408

MAOA 2.644 - - 0.796 0.967 0.881 -

Mlig455_064968 {REF} {Length: 2244} {TRANSSPLICED} {Pfam: Flavin containing amine oxidoreductase [PF01593.26, score=191.6]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=43.1]; FAD dependent oxidoreductase [PF01266.26, score=30.3]; Thi4 family [PF01946.19, score=25.3]; Pyridine nucleotide-disulphide oxidoreductase [PF00070.29, score=24.5]; HI0933-like protein [PF03486.16, score=22.6]; FAD binding domain [PF00890.26, score=21.7]; FAD dependent oxidoreductase [PF12831.9, score=20.4]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=18.9]} {Human: ENSG00000189221, MAOA, monoamine oxidase A, [RH, Score=229, Expect=4e-68]} {Mouse: ENSMUSG00000025037, Maoa, monoamine oxidase A, [RH, Score=236, Expect=3e-71]} {Dmel: FBgn0039177, CG13611, [RH, Score=51.2, Expect=1e-06]} {Celegans: WBGene00000138, amx-2, AMine oXidase family, [Score=78.2, Expect=5e-15]} {Smed: dd_Smed_v6_7098_0_2, dd_Smed_v6_7098_0_2, [RH, Score=325, Expect=4e-106]} {RNA1509_46542} {RNA1310_20650} {RNA815_24826}

Mlig455_066818 {REF} {Length: 1937} {TRANSSPLICED} {Pfam: Flavin containing amine oxidoreductase [PF01593.26, score=191.0]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=43.2]; FAD dependent oxidoreductase [PF01266.26, score=30.7]; Thi4 family [PF01946.19, score=25.9]; Pyridine nucleotide-disulphide oxidoreductase [PF00070.29, score=24.4]; HI0933-like protein [PF03486.16, score=22.5]; FAD binding domain [PF00890.26, score=21.7]; FAD dependent oxidoreductase [PF12831.9, score=20.3]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=18.9]} {Human: ENSG00000189221, MAOA, monoamine oxidase A, [RH, Score=226, Expect=4e-67]} {Mouse: ENSMUSG00000025037, Maoa, monoamine oxidase A, [RH, Score=236, Expect=6e-71]} {Dmel: FBgn0039177, CG13611, [RH, Score=51.2, Expect=2e-06]} {Celegans: WBGene00000138, amx-2, AMine oXidase family, [Score=76.6, Expect=1e-14]} {Smed: dd_Smed_v6_6606_1_1, dd_Smed_v6_6606_1_1, [RH, Score=322, Expect=1e-104]} {RNA1509_46542, RNA1509_58749} {RNA1310_20650, RNA1509_46542, RNA1509_58749} {RNA1509_46542, RNA1509_58749, RNA815_24826}
15. MligTC455_35936 4723 98.4 Mlig455_000144, Mlig455_067733

Neo: -

Age: logFC(26M/2M)=0.248

Region-enriched R5: 1.453/0.00004
Region-enriched R3: 1.201/0.00653
Region-enriched R4: 1.141/0.01645
Region-enriched R6: 1.062/0.04392

ALDH9A1 2.636 - 0.890 0.790 0.956 - -

Mlig455_000144 {REF} {Length: 1983} {TRANSSPLICED} {Pfam: Aldehyde dehydrogenase family [PF00171.24, score=528.7]; Protein of unknown function (DUF1487) [PF07368.13, score=18.5]} {Human: ENSG00000143149, ALDH9A1, aldehyde dehydrogenase 9 family member A1, [RH, Score=536, Expect=0.0]} {Mouse: ENSMUSG00000026687, Aldh9a1, aldehyde dehydrogenase 9, subfamily A1, [RH, Score=515, Expect=2e-179]} {Dmel: FBgn0012036, Aldh, Aldehyde dehydrogenase, [Score=350, Expect=4e-115]} {Celegans: WBGene00000118, alh-12, ALdehyde deHydrogenase, [RH, Score=458, Expect=1e-157]} {Smed: dd_Smed_v6_6827_0_1, dd_Smed_v6_6827_0_1, [RH, Score=530, Expect=0.0]} {RNA1509_2767} {RNA1310_13865, RNA1509_2767} {RNA1509_2767, RNA815_5064}

Mlig455_067733 {REF} {Length: 1983} {TRANSSPLICED} {Pfam: Aldehyde dehydrogenase family [PF00171.24, score=528.2]; Protein of unknown function (DUF1487) [PF07368.13, score=18.5]} {Human: ENSG00000143149, ALDH9A1, aldehyde dehydrogenase 9 family member A1, [RH, Score=535, Expect=0.0]} {Mouse: ENSMUSG00000026687, Aldh9a1, aldehyde dehydrogenase 9, subfamily A1, [RH, Score=514, Expect=8e-179]} {Dmel: FBgn0012036, Aldh, Aldehyde dehydrogenase, [Score=349, Expect=2e-114]} {Celegans: WBGene00000118, alh-12, ALdehyde deHydrogenase, [RH, Score=456, Expect=2e-156]} {Smed: dd_Smed_v6_6827_0_1, dd_Smed_v6_6827_0_1, [RH, Score=529, Expect=0.0]} {RNA1509_2767} {RNA1310_13865} {RNA815_5064}
16. MligTC455_38469 2237 46.61 Mlig455_028190, Mlig455_063554

Neo: -

Age: logFC(26M/2M)=0.551

Region-enriched R4: 2.765/0.00002
Region-enriched R3: 2.517/0.00000
Region-enriched R5: 1.859/0.00156

MFSD2A 2.632 - 0.824 - 0.973 0.835 -

Mlig455_028190 {REF} {Length: 1877} {Pfam: MFS/sugar transport protein [PF13347.8, score=314.5]; Major Facilitator Superfamily [PF07690.18, score=35.3]} {Human: ENSG00000168389, MFSD2A, major facilitator superfamily domain containing 2A, [RH, Score=317, Expect=2e-101]} {Mouse: ENSMUSG00000028655, Mfsd2a, major facilitator superfamily domain containing 2A, [RH, Score=312, Expect=2e-99]} {Smed: dd_Smed_v6_11210_0_1, dd_Smed_v6_11210_0_1, [RH, Score=380, Expect=3e-126]} {RNA1509_5264} {RNA1310_14549} {RNA815_5531}

Mlig455_063554 {REF} {Length: 2339} {Pfam: MFS/sugar transport protein [PF13347.8, score=217.9]; Major Facilitator Superfamily [PF07690.18, score=39.9]} {Human: ENSG00000168389, MFSD2A, major facilitator superfamily domain containing 2A, [RH, Score=223, Expect=1e-68]} {Mouse: ENSMUSG00000037336, Mfsd2b, major facilitator superfamily domain containing 2B, [RH, Score=212, Expect=2e-64]} {Smed: dd_Smed_v6_11210_0_1, dd_Smed_v6_11210_0_1, [Score=274, Expect=8e-87]} {RNA1509_5264} {RNA1310_14549} {RNA815_5531}
17. MligTC455_36727 2161 45.01 Mlig455_013407, Mlig455_013448

Neo: -

Age: logFC(26M/2M)=-0.438

Region-enriched R3: 1.447/0.00030

2.599 - - 0.813 0.972 0.814 -

Mlig455_013407 {REF} {Length: 3635} {RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611} {RNA1310_1688.1, RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611} {RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611, RNA815_14547}

Mlig455_013448 {REF} {Length: 3532} {RNA1509_17696} {RNA1310_1688.1} {RNA815_14547}
18. MligTC455_45369 1901 39.6 Mlig455_004179

Neo: -

Age: -

Region-enriched R3: 1.054/0.03430
Region-enriched R5: 1.022/0.00871

HADH 2.58 - 0.769 - 0.856 - 0.955 Mlig455_004179 {REF} {Length: 1506} {Pfam: 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain [PF02737.20, score=196.8]; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain [PF00725.24, score=126.1]; NAD binding domain of 6-phosphogluconate dehydrogenase [PF03446.17, score=25.2]; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus [PF01210.25, score=25.0]; Alanine dehydrogenase/PNT, C-terminal domain [PF01262.23, score=24.7]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=23.2]; Pyridine nucleotide-disulphide oxidoreductase [PF00070.29, score=22.2]; UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain [PF03721.16, score=22.0]; NADP oxidoreductase coenzyme F420-dependent [PF03807.19, score=20.0]; Glucose inhibited division protein A [PF01134.24, score=19.0]} {Human: ENSG00000138796, HADH, hydroxyacyl-CoA dehydrogenase, [RH, Score=349, Expect=3e-120]} {Mouse: ENSMUSG00000027984, Hadh, hydroxyacyl-Coenzyme A dehydrogenase, [RH, Score=353, Expect=3e-122]} {Dmel: FBgn0028479, Mtpalpha, Mitochondrial trifunctional protein alpha subunit, [Score=161, Expect=3e-44]} {Celegans: WBGene00007129, B0272.3, Probable 3-hydroxyacyl-CoA dehydrogenase B0272.3, [RH, Score=344, Expect=6e-119]} {Smed: dd_Smed_v6_725_0_2, dd_Smed_v6_725_0_2, [RH, Score=360, Expect=4e-125]} {RNA1509_1812, RNA1509_37805, RNA1509_50466} {RNA1310_24898.2, RNA1509_1812, RNA1509_37805, RNA1509_50466} {RNA1509_1812, RNA1509_37805, RNA1509_50466, RNA815_10112.1}
19. MligTC455_37239 1846 38.46 Mlig455_060082

Neo: -

Age: -

Region-enriched R3: 1.562/0.04763
Region-enriched R5: 1.292/0.04648

PANK4 2.572 - 0.817 0.776 0.979 - - Mlig455_060082 {REF} {Length: 1532} {Pfam: Fumble [PF03630.16, score=120.5]} {Human: ENSG00000273494, PANK4, pantothenate kinase 4, [Score=106, Expect=2e-24]; ENSG00000157881, PANK4, pantothenate kinase 4, [Score=106, Expect=2e-24]} {Mouse: ENSMUSG00000029056, Pank4, pantothenate kinase 4, [Score=97.4, Expect=1e-21]} {Dmel: FBgn0011205, fbl, fumble, [Score=66.2, Expect=7e-12]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [Score=170, Expect=1e-49]} {RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233} {RNA1310_20224, RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233} {RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233, RNA815_7673}
20. MligTC455_52040 2198 45.8 Mlig455_029597

Neo: Germline

Age: logFC(26M/2M)=0.256

Region-enriched R3: 1.723/0.00072
Region-enriched R5: 1.481/0.00114

VIL1 2.572 - 0.765 - 0.950 0.857 - Mlig455_029597 {REF} {Length: 2577} {Pfam: Gelsolin repeat [PF00626.24, score=113.7]} {Human: ENSG00000127831, VIL1, villin 1, [Score=182, Expect=5e-53]; ENSG00000148180, GSN, gelsolin, [Score=179, Expect=1e-49]; ENSG00000135407, AVIL, advillin, [Score=174, Expect=1e-47]} {Mouse: ENSMUSG00000026879, Gsn, gelsolin, [Score=185, Expect=7e-52]; ENSMUSG00000026175, Vil1, villin 1, [Score=182, Expect=1e-50]} {Dmel: FBgn0010225, Gel, Gelsolin, [Score=194, Expect=3e-55]} {Celegans: WBGene00010593, gsnl-1, Gelsolin-like protein 1, [Score=164, Expect=4e-46]} {Smed: dd_Smed_v6_1215_0_1, dd_Smed_v6_1215_0_1, [RH, Score=403, Expect=3e-140]} {RNA1509_12411, RNA1509_17911, RNA1509_2858, RNA1509_30271, RNA1509_44412, RNA1509_44633} {RNA1310_15610, RNA1509_12411, RNA1509_17911, RNA1509_2858, RNA1509_30271, RNA1509_44412, RNA1509_44633} {RNA1509_12411, RNA1509_17911, RNA1509_2858, RNA1509_30271, RNA1509_44412, RNA1509_44633, RNA815_7841}
21. MligTC455_18668 1636 34.09 Mlig455_012434, Mlig455_012558, Mlig455_012563, Mlig455_027620

Neo: Int S/G2/M

Age: -

Region-enriched R5: 1.208/0.04430

2.57 - - - 0.823 0.796 0.951

Mlig455_012434 {REF} {Length: 2933} {RNA1509_24772} {RNA1310_6123.1} {RNA815_1284.1}

Mlig455_012558 {REF} {Length: 3241} {TRANSSPLICED} {RNA1509_24772} {RNA1310_6123.1, RNA1509_24772} {RNA1509_24772, RNA815_1284.1}

Mlig455_012563 {REF} {Length: 2852} {TRANSSPLICED} {RNA1509_24772} {RNA1310_6123.1} {RNA815_1284.1}

Mlig455_027620 {REF} {Length: 432} {NoTransDecoderORF} {RNA1310_82755} {RNA815_51913}
22. MligTC455_18868 1328 27.67 Mlig455_067483

Neo: -

Age: -

Region-enriched R3: 1.928/0.00492
Region-enriched R4: 1.837/0.01691
Region-enriched R5: 1.462/0.02245

2.553 0.755 - - 0.978 0.820 - Mlig455_067483 {REF} {Length: 405} {RNA1509_5037} {RNA1310_19379} {RNA815_6182.1}
23. MligTC455_37973 1270 26.46 Mlig455_055227

Neo: -

Age: Down-Up-Up

Region-enriched R4: 1.059/0.03046

ASAH1 2.543 - 0.787 - 0.965 0.791 - Mlig455_055227 {REF} {Length: 1456} {TRANSSPLICED} {Pfam: Linear amide C-N hydrolases, choloylglycine hydrolase family [PF02275.20, score=83.8]; beta subunit of N-acylethanolamine-hydrolyzing acid amidase [PF15508.8, score=40.2]} {Human: ENSG00000104763, ASAH1, N-acylsphingosine amidohydrolase 1, [Score=360, Expect=5e-122]} {Mouse: ENSMUSG00000031591, Asah1, N-acylsphingosine amidohydrolase 1, [Score=352, Expect=2e-119]} {Celegans: WBGene00010769, asah-1, Acid ceramidase, [Score=281, Expect=1e-91]} {RNA1509_25332, RNA1509_26010, RNA1509_9884} {RNA1310_24069.1, RNA1509_25332, RNA1509_26010, RNA1509_9884} {RNA1509_25332, RNA1509_26010, RNA1509_9884, RNA815_9637.1}
24. MligTC455_18869 1346 28.04 Mlig455_067491

Neo: -

Age: -

Region-enriched R3: 1.933/0.00397
Region-enriched R4: 1.775/0.01938
Region-enriched R5: 1.440/0.02287

2.542 0.754 - - 0.978 0.810 - Mlig455_067491 {REF} {Length: 2320} {Pfam: NAD dependent epimerase/dehydratase family [PF01370.23, score=72.5]; GDP-mannose 4,6 dehydratase [PF16363.7, score=51.3]; 3-beta hydroxysteroid dehydrogenase/isomerase family [PF01073.21, score=46.4]; Male sterility protein [PF07993.14, score=42.2]; NAD(P)H-binding [PF13460.8, score=39.3]; Polysaccharide biosynthesis protein [PF02719.17, score=30.0]; KR domain [PF08659.12, score=29.5]; NmrA-like family [PF05368.15, score=28.0]; short chain dehydrogenase [PF00106.27, score=19.3]} {Celegans: WBGene00017429, F13D11.4, [RH, Score=213, Expect=4e-66]} {RNA1509_20033, RNA1509_5037} {RNA1310_19379, RNA1509_20033, RNA1509_5037} {RNA1509_20033, RNA1509_5037, RNA815_6182.1}
25. MligTC455_20725 2475 51.57 Mlig455_035227

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.822

Region-enriched R3: 2.240/0.00003

SLC1A6 2.542 - 0.795 - 0.971 0.776 - Mlig455_035227 {REF} {Length: 2154} {Pfam: Sodium:dicarboxylate symporter family [PF00375.20, score=422.3]} {Human: ENSG00000105143, SLC1A6, solute carrier family 1 member 6, [RH, Score=462, Expect=2e-157]} {Mouse: ENSMUSG00000024935, Slc1a1, solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1, [RH, Score=456, Expect=3e-156]; ENSMUSG00000005357, Slc1a6, solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6, [RH, Score=452, Expect=1e-153]} {Dmel: FBgn0026439, Eaat1, Excitatory amino acid transporter 1, [RH, Score=373, Expect=3e-124]} {Celegans: WBGene00001620, glt-1, Excitatory amino acid transporter, [Score=422, Expect=3e-143]} {Smed: dd_Smed_v6_1106_0_1, dd_Smed_v6_1106_0_1, [Score=422, Expect=8e-144]} {RNA1509_7401} {RNA1310_8553.1, RNA1509_7401} {RNA1509_7401, RNA815_2974.1}
26. MligTC455_50387 1074 22.38 Mlig455_018618

Neo: -

Age: logFC(26M/2M)=0.362

Region-enriched R4: 2.247/0.00001
Region-enriched R3: 1.935/0.00000

SLC8B1 2.54 - 0.762 - 0.951 0.827 - Mlig455_018618 {REF} {Length: 2020} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=96.0]} {Human: ENSG00000089060, SLC8B1, solute carrier family 8 member B1, [RH, Score=214, Expect=1e-62]} {Mouse: ENSMUSG00000032754, Slc8b1, solute carrier family 8 (sodium/lithium/calcium exchanger), member B1, [RH, Score=220, Expect=4e-65]} {Dmel: FBgn0033324, CG14744, [Score=126, Expect=8e-31]} {Celegans: WBGene00003572, ncx-7, Putative sodium/calcium exchanger 7, [RH, Score=168, Expect=3e-45]} {Smed: dd_Smed_v6_1009_1_1, dd_Smed_v6_1009_1_1, [RH, Score=254, Expect=2e-80]} {RNA1509_17694, RNA1509_27887, RNA1509_3073} {RNA1310_3165.1, RNA1509_17694, RNA1509_27887} {RNA1509_17694, RNA1509_27887, RNA815_1390}
27. MligTC455_26894 254 5.29 Mlig455_013003

Neo: -

Age: -

Region-enriched R4: 4.231/0.00003
Region-enriched R5: 3.493/0.00001
Region-enriched R6: 2.802/0.00935

2.523 - - - 0.795 0.742 0.986 Mlig455_013003 {REF} {Length: 782} {RNA1509_35352} {RNA1310_7853.1} {RNA815_5910}
28. MligTC455_24085 1786 37.2 Mlig455_007320

Neo: -

Age: logFC(26M/2M)=0.210

Region-enriched R3: 2.481/0.00000
Region-enriched R5: 1.136/0.04856

ACHE 2.479 - 0.725 - 0.974 0.780 - Mlig455_007320 {REF} {Length: 2268} {Pfam: Carboxylesterase family [PF00135.30, score=353.8]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=232, Expect=2e-67]} {Mouse: ENSMUSG00000023328, Ache, acetylcholinesterase, [Score=227, Expect=1e-65]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=202, Expect=2e-56]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=223, Expect=2e-64]} {Smed: dd_Smed_v6_14790_0_1, dd_Smed_v6_14790_0_1, [Score=206, Expect=5e-58]} {RNA1509_28908, RNA1509_31228, RNA1509_46106} {RNA1310_10437.1, RNA1509_28908, RNA1509_31228, RNA1509_46106} {RNA1509_28908, RNA1509_31228, RNA1509_46106, RNA815_3976}
29. MligTC455_41971 516 10.74 Mlig455_017945

Neo: -

Age: logFC(26M/2M)=0.472

2.471 - - - 0.804 0.711 0.956 Mlig455_017945 {REF} {Length: 3869} {TRANSSPLICED} {Pfam: Myosin head (motor domain) [PF00063.23, score=43.5]} {RNA1509_13660} {RNA1310_2845.1} {RNA815_872.1}
30. MligTC455_35949 279 5.81 Mlig455_011030

Neo: -

Age: -

Region-enriched R3: 2.439/0.03369
Region-enriched R5: 2.149/0.02386

DIRC2 2.47 - 0.814 - 0.954 0.702 - Mlig455_011030 {REF} {Length: 1623} {TRANSSPLICED} {Pfam: Major Facilitator Superfamily [PF07690.18, score=70.1]} {Human: ENSG00000138463, DIRC2, disrupted in renal carcinoma 2, [RH, Score=194, Expect=4e-56]} {Mouse: ENSMUSG00000022848, Dirc2, disrupted in renal carcinoma 2 (human), [RH, Score=197, Expect=1e-57]} {Celegans: WBGene00015632, C09D4.1, Uncharacterized MFS-type transporter C09D4.1, [Score=102, Expect=2e-23]} {Smed: dd_Smed_v6_12577_0_1, dd_Smed_v6_12577_0_1, [Score=145, Expect=9e-39]} {RNA1509_19444} {RNA1310_8463, RNA1509_19444} {RNA1509_19444, RNA815_7671}
31. MligTC455_49184 1381 28.77 Mlig455_016548

Neo: -

Age: Down-Down-Up

GPT2 2.463 - - - 0.750 0.751 0.962 Mlig455_016548 {REF} {Length: 2052} {TRANSSPLICED} {Pfam: Aminotransferase class I and II [PF00155.23, score=108.3]} {Human: ENSG00000166123, GPT2, glutamic--pyruvic transaminase 2, [RH, Score=593, Expect=0.0]; ENSG00000167701, GPT, glutamic--pyruvic transaminase, [RH, Score=578, Expect=0.0]} {Mouse: ENSMUSG00000022546, Gpt, glutamic pyruvic transaminase, soluble, [RH, Score=595, Expect=0.0]; ENSMUSG00000031700, Gpt2, glutamic pyruvate transaminase (alanine aminotransferase) 2, [RH, Score=584, Expect=0.0]} {Dmel: FBgn0030478, CG1640, [RH, Score=570, Expect=0.0]} {Celegans: WBGene00016333, C32F10.8, [RH, Score=526, Expect=0.0]} {Smed: dd_Smed_v6_2988_0_1, dd_Smed_v6_2988_0_1, [RH, Score=622, Expect=0.0]} {RNA1509_1046} {RNA1310_11434.1} {RNA815_4934.1}
32. MligTC455_45572 697 14.53 Mlig455_014345

Neo: -

Age: -

Region-enriched R4: 2.663/0.00001
Region-enriched R3: 1.769/0.00087
Region-enriched R5: 1.541/0.00135
Region-enriched R6: 1.390/0.04169

CRYL1 2.462 - 0.702 0.803 0.957 - - Mlig455_014345 {REF} {Length: 1372} {Pfam: 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain [PF02737.20, score=152.8]; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain [PF00725.24, score=40.7]} {Human: ENSG00000165475, CRYL1, crystallin lambda 1, [RH, Score=275, Expect=6e-91]} {Mouse: ENSMUSG00000021947, Cryl1, crystallin, lambda 1, [RH, Score=261, Expect=7e-86]} {Dmel: FBgn0030737, CG9914, [RH, Score=287, Expect=4e-96]} {Celegans: WBGene00022130, Y71F9B.9, [RH, Score=249, Expect=2e-81]} {Smed: dd_Smed_v6_1696_0_1, dd_Smed_v6_1696_0_1, [RH, Score=176, Expect=6e-53]} {RNA1509_34725} {RNA1310_23652} {RNA815_8421.1}
33. MligTC455_45590 6933 144.44 Mlig455_060243

Neo: -

Age: Up-Down-Down

Region-enriched R3: 1.918/0.00019

MRC1 2.461 - 0.713 - 0.960 0.788 - Mlig455_060243 {REF} {Length: 4769} {Pfam: Lectin C-type domain [PF00059.23, score=548.8]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=62.0]; Extracellular link domain [PF00193.19, score=22.4]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [RH, Score=513, Expect=2e-156]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [RH, Score=485, Expect=1e-146]} {Dmel: FBgn0035199, tfc, triforce, [Score=57.4, Expect=8e-09]} {Celegans: WBGene00020191, clec-53, C-type LECtin, [RH, Score=103, Expect=1e-23]} {Smed: dd_Smed_v6_3193_0_2, dd_Smed_v6_3193_0_2, [Score=209, Expect=1e-54]} {RNA1509_169} {RNA1310_579} {RNA815_112.1}
34. MligTC455_35670 353 7.35 Mlig455_000478, Mlig455_000513

Neo: -

Age: logFC(26M/2M)=0.556

AC099489.1 2.452 - 0.759 - 0.957 0.736 -

Mlig455_000478 {REF} {Length: 11127} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=93.5]; Domain of unknown function (DUF1943) [PF09172.13, score=67.6]} {Human: ENSG00000188897, AC099489.1, vitellogenin, [Score=131, Expect=1e-29]} {Dmel: FBgn0087002, apolpp, apolipophorin, [Score=61.2, Expect=8e-09]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=91.7, Expect=3e-18]} {RNA1509_27087, RNA1509_28440} {RNA1310_65.2, RNA1509_28440} {RNA1509_28440, RNA815_55}

Mlig455_000513 {REF} {Length: 2538} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=41.7]} {Human: ENSG00000188897, AC099489.1, vitellogenin, [Score=68.6, Expect=2e-11]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=60.8, Expect=2e-09]} {RNA1509_27087} {RNA1310_65.2} {RNA815_55}
35. MligTC455_45640 354 7.37 Mlig455_044849

Neo: -

Age: -

Region-enriched R4: 1.921/0.00612

NFAT5 2.446 0.723 0.729 - - - 0.994 Mlig455_044849 {REF} {Length: 2286} {Human: ENSG00000102908, NFAT5, nuclear factor of activated T cells 5, [Score=70.1, Expect=3e-13]} {Mouse: ENSMUSG00000003847, Nfat5, nuclear factor of activated T cells 5, [Score=71.2, Expect=8e-14]} {Dmel: FBgn0030505, NFAT, NFAT nuclear factor, [Score=64.3, Expect=1e-11]} {Smed: dd_Smed_v6_5978_0_1, dd_Smed_v6_5978_0_1, [Score=75.5, Expect=1e-15]} {RNA1509_28577} {RNA1310_61235.1} {RNA815_20233.1}
36. MligTC455_23627 591 12.32 Mlig455_015297

Neo: -

Age: -

Region-enriched R5: 1.344/0.00701

NUBP1 2.442 - - 0.705 0.787 - 0.950 Mlig455_015297 {REF} {Length: 1975} {TRANSSPLICED} {Pfam: NUBPL iron-transfer P-loop NTPase [PF10609.11, score=299.7]; CobQ/CobB/MinD/ParA nucleotide binding domain [PF01656.25, score=32.5]; AAA domain [PF13614.8, score=25.4]; AAA domain [PF13500.8, score=23.4]; Anion-transporting ATPase [PF02374.17, score=20.5]} {Human: ENSG00000103274, NUBP1, nucleotide binding protein 1, [RH, Score=379, Expect=7e-132]} {Mouse: ENSMUSG00000022503, Nubp1, nucleotide binding protein 1, [RH, Score=387, Expect=5e-135]} {Dmel: FBgn0032597, CG17904, [RH, Score=315, Expect=5e-107]} {Celegans: WBGene00008664, nubp-1, Cytosolic Fe-S cluster assembly factor NUBP1 homolog, [RH, Score=363, Expect=7e-126]} {Smed: dd_Smed_v6_3014_0_1, dd_Smed_v6_3014_0_1, [RH, Score=332, Expect=2e-113]} {RNA1509_14102, RNA1509_16309, RNA1509_18516} {RNA1310_15145.1, RNA1509_14102, RNA1509_16309, RNA1509_18516} {RNA1509_14102, RNA1509_16309, RNA1509_18516, RNA815_12756}
37. MligTC455_47632 1274 26.54 Mlig455_021530

Neo: -

Age: Down-Up-Up

Region-enriched R4: 2.128/0.00004
Region-enriched R3: 1.330/0.02022
Region-enriched R5: 1.147/0.01776

2.436 - 0.716 0.761 0.959 - - Mlig455_021530 {REF} {Length: 949} {Pfam: Universal stress protein family [PF00582.28, score=103.9]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=130, Expect=1e-39]} {RNA1509_13699, RNA1509_6559} {RNA1310_39993, RNA1509_13699, RNA1509_6559} {RNA1509_13699, RNA1509_6559, RNA815_18311}
38. MligTC455_03323 3504 73.01 Mlig455_019870

Neo: -

Age: -

Region-enriched R6: 2.716/0.00002

XPNPEP2 2.422 - 0.714 0.741 0.967 - - Mlig455_019870 {REF} {Length: 2912} {Pfam: Metallopeptidase family M24 [PF00557.26, score=120.7]; Creatinase/Prolidase N-terminal domain [PF16189.7, score=108.0]; C-terminal region of peptidase_M24 [PF16188.7, score=74.7]} {Human: ENSG00000122121, XPNPEP2, X-prolyl aminopeptidase 2, [Score=328, Expect=2e-102]; ENSG00000108039, XPNPEP1, X-prolyl aminopeptidase 1, [Score=322, Expect=4e-100]} {Mouse: ENSMUSG00000037005, Xpnpep2, X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound, [Score=324, Expect=6e-101]; ENSMUSG00000025027, Xpnpep1, X-prolyl aminopeptidase (aminopeptidase P) 1, soluble, [Score=322, Expect=5e-100]} {Dmel: FBgn0026150, ApepP, Aminopeptidase P, [Score=301, Expect=4e-93]} {Celegans: WBGene00000155, app-1, Xaa-Pro aminopeptidase app-1, [Score=251, Expect=2e-74]} {Smed: dd_Smed_v6_4029_0_1, dd_Smed_v6_4029_0_1, [Score=295, Expect=6e-91]} {RNA1509_3646, RNA1509_9018, RNA1509_968} {RNA1310_7569, RNA1509_3646, RNA1509_9018, RNA1509_968} {RNA1509_3646, RNA1509_9018, RNA1509_968, RNA815_2489}
39. MligTC455_35756 521 10.85 Mlig455_015265

Neo: -

Age: -

Region-enriched R5: 3.153/0.00000

2.422 - 0.728 - 0.730 - 0.964 Mlig455_015265 {REF} {Length: 2098} {RNA1509_8215} {RNA1310_9407.1} {RNA815_2518.1}
40. MligTC455_19955 2064 42.99 Mlig455_014277, Mlig455_014328

Neo: -

Age: -

Region-enriched R4: 1.732/0.00087
Region-enriched R5: 1.027/0.01771

PHYHD1 2.418 - 0.743 - 0.960 0.715 -

Mlig455_014277 {REF} {Length: 1311} {TRANSSPLICED} {Pfam: Phytanoyl-CoA dioxygenase (PhyH) [PF05721.15, score=178.4]} {Human: ENSG00000175287, PHYHD1, phytanoyl-CoA dioxygenase domain containing 1, [RH, Score=238, Expect=3e-77]} {Mouse: ENSMUSG00000079484, Phyhd1, phytanoyl-CoA dioxygenase domain containing 1, [RH, Score=232, Expect=1e-74]} {Dmel: FBgn0037819, CG14688, [RH, Score=205, Expect=1e-64]} {Celegans: WBGene00013650, Y105C5B.9, Phytanoyl-CoA dioxygenase domain-containing protein 1 homolog, [RH, Score=220, Expect=1e-70]} {Smed: dd_Smed_v6_8029_0_1, dd_Smed_v6_8029_0_1, [RH, Score=249, Expect=7e-82]} {RNA1509_18487} {RNA1310_28843.1} {RNA815_12227}

Mlig455_014328 {REF} {Length: 1306} {TRANSSPLICED} {Pfam: Phytanoyl-CoA dioxygenase (PhyH) [PF05721.15, score=178.5]} {Human: ENSG00000175287, PHYHD1, phytanoyl-CoA dioxygenase domain containing 1, [RH, Score=239, Expect=2e-77]} {Mouse: ENSMUSG00000079484, Phyhd1, phytanoyl-CoA dioxygenase domain containing 1, [RH, Score=233, Expect=6e-75]} {Dmel: FBgn0037819, CG14688, [RH, Score=204, Expect=2e-64]} {Celegans: WBGene00013650, Y105C5B.9, Phytanoyl-CoA dioxygenase domain-containing protein 1 homolog, [RH, Score=218, Expect=9e-70]} {Smed: dd_Smed_v6_8029_0_1, dd_Smed_v6_8029_0_1, [RH, Score=248, Expect=1e-81]} {RNA1509_18487} {RNA1310_28843.1} {RNA815_12227}
41. MligTC455_24161 394 8.22 Mlig455_014023

Neo: -

Age: -

2.415 - 0.732 - 0.716 - 0.967 Mlig455_014023 {REF} {Length: 4313} {Pfam: Prominin [PF05478.13, score=32.3]} {Smed: dd_Smed_v6_6330_0_1, dd_Smed_v6_6330_0_1, [RH, Score=92.0, Expect=9e-19]} {RNA1509_15237, RNA1509_51109} {RNA1310_2052, RNA1509_15237, RNA1509_51109} {RNA1509_15237, RNA1509_51109, RNA815_750}
42. MligTC455_35757 1057 22.03 Mlig455_015143, Mlig455_015268

Neo: -

Age: -

Region-enriched R5: 2.988/0.00000

SLC47A1, SLC47A2 2.414 - 0.727 - 0.731 - 0.956

Mlig455_015143 {REF} {Length: 3745} {Pfam: MatE [PF01554.20, score=191.7]} {Human: ENSG00000142494, SLC47A1, solute carrier family 47 member 1, [RH, Score=314, Expect=4e-98]; ENSG00000180638, SLC47A2, solute carrier family 47 member 2, [RH, Score=314, Expect=7e-98]} {Mouse: ENSMUSG00000069855, Slc47a2, solute carrier family 47, member 2, [RH, Score=312, Expect=2e-97]} {Smed: dd_Smed_v6_7241_0_1, dd_Smed_v6_7241_0_1, [RH, Score=428, Expect=4e-141]} {RNA1509_34899, RNA1509_39511, RNA1509_8215} {RNA1310_9407.1, RNA1509_34899, RNA1509_39511, RNA1509_8215} {RNA1509_34899, RNA1509_39511, RNA1509_8215, RNA815_2518.1}

Mlig455_015268 {REF} {Length: 3881} {Pfam: MatE [PF01554.20, score=193.3]} {Human: ENSG00000180638, SLC47A2, solute carrier family 47 member 2, [RH, Score=302, Expect=2e-94]} {Mouse: ENSMUSG00000069855, Slc47a2, solute carrier family 47, member 2, [RH, Score=310, Expect=2e-97]} {Smed: dd_Smed_v6_7241_0_1, dd_Smed_v6_7241_0_1, [RH, Score=415, Expect=2e-137]} {RNA1509_8215} {RNA1310_9407.1} {RNA815_2518.1}
43. MligTC455_51563 139 2.9 Mlig455_004055

Neo: -

Age: -

AUH 2.397 - - - 0.710 0.725 0.962 Mlig455_004055 {REF} {Length: 1051} {TRANSSPLICED} {Pfam: Enoyl-CoA hydratase/isomerase [PF00378.22, score=199.5]; Enoyl-CoA hydratase/isomerase [PF16113.7, score=114.5]} {Human: ENSG00000148090, AUH, AU RNA binding methylglutaconyl-CoA hydratase, [RH, Score=260, Expect=3e-85]; ENSG00000121310, ECHDC2, enoyl-CoA hydratase domain containing 2, [RH, Score=255, Expect=7e-84]} {Mouse: ENSMUSG00000028601, Echdc2, enoyl Coenzyme A hydratase domain containing 2, [RH, Score=259, Expect=1e-85]; ENSMUSG00000021460, Auh, AU RNA binding protein/enoyl-coenzyme A hydratase, [RH, Score=258, Expect=7e-85]} {Dmel: FBgn0033761, CG8778, [RH, Score=275, Expect=8e-92]} {Celegans: WBGene00001154, ech-5, Enoyl-CoA Hydratase, [RH, Score=232, Expect=3e-75]} {Smed: dd_Smed_v6_3553_0_1, dd_Smed_v6_3553_0_1, [RH, Score=291, Expect=2e-98]} {RNA1509_30724} {RNA1310_10747.1} {RNA815_15836}
44. MligTC455_42224 691 14.4 Mlig455_012381, Mlig455_012802

Neo: -

Age: logFC(26M/2M)=-0.411

Region-enriched R4: 3.746/0.00086
Region-enriched R3: 3.098/0.00277

ENTPD6 2.369 - - 0.708 0.954 0.707 -

Mlig455_012381 {REF} {Length: 2018} {Pfam: GDA1/CD39 (nucleoside phosphatase) family [PF01150.19, score=209.9]; Ppx/GppA phosphatase family [PF02541.18, score=18.1]} {Human: ENSG00000197586, ENTPD6, ectonucleoside triphosphate diphosphohydrolase 6 (putative), [Score=196, Expect=9e-57]} {Mouse: ENSMUSG00000033068, Entpd6, ectonucleoside triphosphate diphosphohydrolase 6, [Score=196, Expect=5e-57]; ENSMUSG00000021236, Entpd5, ectonucleoside triphosphate diphosphohydrolase 5, [Score=189, Expect=2e-54]} {Dmel: FBgn0024947, NTPase, [Score=165, Expect=8e-46]} {Celegans: WBGene00010697, uda-1, Nucleoside-diphosphatase uda-1, [Score=144, Expect=6e-38]} {Smed: dd_Smed_v6_8855_0_2, dd_Smed_v6_8855_0_2, [Score=178, Expect=8e-51]} {RNA1509_19635, RNA1509_40383, RNA1509_54757} {RNA1310_14737, RNA1509_19635, RNA1509_40383, RNA1509_54757} {RNA1509_19635, RNA1509_40383, RNA1509_54757, RNA815_6957}

Mlig455_012802 {REF} {Length: 1599} {Pfam: GDA1/CD39 (nucleoside phosphatase) family [PF01150.19, score=124.4]; Ppx/GppA phosphatase family [PF02541.18, score=18.4]} {Human: ENSG00000197586, ENTPD6, ectonucleoside triphosphate diphosphohydrolase 6 (putative), [Score=138, Expect=7e-36]; ENSG00000187097, ENTPD5, ectonucleoside triphosphate diphosphohydrolase 5, [Score=134, Expect=9e-35]} {Mouse: ENSMUSG00000033068, Entpd6, ectonucleoside triphosphate diphosphohydrolase 6, [Score=138, Expect=3e-36]; ENSMUSG00000021236, Entpd5, ectonucleoside triphosphate diphosphohydrolase 5, [Score=132, Expect=3e-34]} {Dmel: FBgn0024947, NTPase, [Score=118, Expect=5e-29]} {Celegans: WBGene00010697, uda-1, Nucleoside-diphosphatase uda-1, [Score=95.1, Expect=4e-21]} {Smed: dd_Smed_v6_8855_0_2, dd_Smed_v6_8855_0_2, [Score=120, Expect=3e-30]} {RNA1509_40383, RNA1509_51501} {RNA1310_14737, RNA1509_51501} {RNA1509_51501, RNA815_6957}
45. MligTC455_19366 2365 49.28 Mlig455_029830

Neo: -

Age: -

Region-enriched R3: 1.992/0.00057
Region-enriched R5: 1.418/0.01296

PANK3 1.934 - - - 0.971 - 0.963 Mlig455_029830 {REF} {Length: 1495} {Pfam: Fumble [PF03630.16, score=108.9]} {Human: ENSG00000120137, PANK3, pantothenate kinase 3, [Score=57.0, Expect=2e-08]; ENSG00000152782, PANK1, pantothenate kinase 1, [Score=56.6, Expect=3e-08]; ENSG00000125779, PANK2, pantothenate kinase 2, [Score=55.1, Expect=5e-08]} {Mouse: ENSMUSG00000018846, Pank3, pantothenate kinase 3, [Score=56.6, Expect=2e-08]; ENSMUSG00000033610, Pank1, pantothenate kinase 1, [Score=56.2, Expect=2e-08]; ENSMUSG00000037514, Pank2, pantothenate kinase 2, [Score=55.8, Expect=4e-08]} {Dmel: FBgn0011205, fbl, fumble, [Score=55.1, Expect=5e-08]} {Smed: dd_Smed_v6_994_0_1, dd_Smed_v6_994_0_1, [RH, Score=227, Expect=2e-71]} {RNA1509_1801} {RNA1310_24657, RNA1509_1801} {RNA1509_1801, RNA815_10326}
46. MligTC455_29744 129 2.68 Mlig455_030037

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=1.434

URGCP 1.925 - - - 0.930 - 0.995 Mlig455_030037 {REF} {Length: 8092} {Pfam: Root hair defective 3 GTP-binding protein (RHD3) [PF05879.14, score=31.2]; Dynamin family [PF00350.25, score=19.4]; 50S ribosome-binding GTPase [PF01926.25, score=18.9]} {Human: ENSG00000106608, URGCP, upregulator of cell proliferation, [Score=132, Expect=2e-30]} {Mouse: ENSMUSG00000045868, Gvin1, GTPase, very large interferon inducible 1, [Score=510, Expect=3e-148]; ENSMUSG00000078606, Gm4070, predicted gene 4070, [Score=510, Expect=2e-148]} {RNA1509_12278, RNA1509_1879} {RNA1310_768, RNA1509_12278, RNA1509_1879} {RNA1509_12278, RNA1509_1879, RNA815_2116.1}
47. MligTC455_38242 389 8.09 Mlig455_029203

Neo: -

Age: logFC(26M/2M)=0.403

RAB37 1.912 - - - 0.929 - 0.983 Mlig455_029203 {REF} {Length: 1188} {Pfam: Ras family [PF00071.24, score=178.7]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=104.8]; ADP-ribosylation factor family [PF00025.23, score=50.1]; 50S ribosome-binding GTPase [PF01926.25, score=23.0]; AAA domain [PF13479.8, score=21.5]} {Human: ENSG00000172794, RAB37, RAB37, member RAS oncogene family, [RH, Score=202, Expect=2e-65]; ENSG00000167964, RAB26, RAB26, member RAS oncogene family, [RH, Score=199, Expect=2e-63]} {Mouse: ENSMUSG00000020732, Rab37, RAB37, member RAS oncogene family, [RH, Score=203, Expect=1e-65]; ENSMUSG00000079657, Rab26, RAB26, member RAS oncogene family, [RH, Score=200, Expect=2e-63]} {Dmel: FBgn0086913, Rab26, [RH, Score=201, Expect=1e-62]} {Celegans: WBGene00004285, rab-37, RAB family, [RH, Score=177, Expect=2e-55]} {Smed: dd_Smed_v6_3485_0_1, dd_Smed_v6_3485_0_1, [Score=167, Expect=4e-52]} {RNA1509_41873} {RNA1310_29441, RNA1509_41873} {RNA1509_41873, RNA815_14790.1}
48. MligTC455_02592 360 7.51 Mlig455_012040, Mlig455_067503

Neo: -

Age: Up-Up-Down

MX2 1.905 - - - 0.920 - 0.985

Mlig455_012040 {REF} {Length: 1839} {RNA1310_58944}

Mlig455_067503 {REF} {Length: 4597} {Pfam: Dynamin central region [PF01031.22, score=151.5]; Dynamin family [PF00350.25, score=125.5]; Dynamin GTPase effector domain [PF02212.20, score=54.1]; 50S ribosome-binding GTPase [PF01926.25, score=24.4]; AAA ATPase domain [PF13175.8, score=21.6]; Family with sequence similarity 184, A and B [PF15665.7, score=19.1]} {Human: ENSG00000183486, MX2, MX dynamin like GTPase 2, [RH, Score=349, Expect=3e-110]; ENSG00000157601, MX1, MX dynamin like GTPase 1, [RH, Score=336, Expect=1e-105]} {Mouse: ENSMUSG00000023341, Mx2, MX dynamin-like GTPase 2, [RH, Score=342, Expect=2e-108]} {Dmel: FBgn0003392, shi, shibire, [Score=152, Expect=3e-38]} {Celegans: WBGene00001130, dyn-1, Dynamin, [Score=164, Expect=3e-42]} {Smed: dd_Smed_v6_1818_0_1, dd_Smed_v6_1818_0_1, [Score=162, Expect=2e-42]} {RNA1509_19894} {RNA1310_1482.2} {RNA815_3194}
49. MligTC455_36114 85 1.77 Mlig455_041185

Neo: -

Age: logFC(26M/2M)=0.455

Regeneration-upregulated R2: 4.654

Regeneration-enriched R2: 4.654

RGN 1.873 - - - 0.920 - 0.953 Mlig455_041185 {REF} {Length: 1610} {TRANSSPLICED} {Pfam: SMP-30/Gluconolactonase/LRE-like region [PF08450.14, score=217.7]; Two component regulator propeller [PF07494.13, score=25.1]; NHL repeat [PF01436.23, score=24.9]} {Human: ENSG00000130988, RGN, regucalcin, [Score=166, Expect=5e-49]} {Mouse: ENSMUSG00000023070, Rgn, regucalcin, [Score=168, Expect=3e-50]} {Dmel: FBgn0038257, smp-30, Senescence marker protein-30, [Score=149, Expect=7e-43]} {Smed: dd_Smed_v6_3808_0_1, dd_Smed_v6_3808_0_1, [Score=162, Expect=3e-48]} {RNA1509_28387} {RNA1310_7497.2} {RNA815_8819.2}
50. MligTC455_40682 2549 53.1 Mlig455_013284, Mlig455_035928

Neo: -

Age: -

Region-enriched R3: 1.724/0.00155
Region-enriched R4: 1.452/0.02174
Region-enriched R5: 1.104/0.04518

1.857 - - - 0.956 0.901 -

Mlig455_013284 {REF} {Length: 2073} {Pfam: Tctex-1 family [PF03645.15, score=31.9]} {Mouse: ENSMUSG00000079710, Gm3448, predicted gene 3448, [Score=50.1, Expect=3e-07]; ENSMUSG00000079707, Tcte3, t-complex-associated testis expressed 3, [Score=50.1, Expect=3e-07]; ENSMUSG00000116780, Gm3417, predicted gene 3417, [Score=48.9, Expect=6e-07]} {Smed: dd_Smed_v6_12108_0_1, dd_Smed_v6_12108_0_1, [Score=57.8, Expect=2e-10]} {RNA1509_11021, RNA1509_22678} {RNA1310_29221, RNA1509_11021, RNA1509_22678} {RNA1509_11021, RNA1509_22678, RNA815_16910}

Mlig455_035928 {REF} {Length: 1424} {Pfam: Tctex-1 family [PF03645.15, score=31.7]} {Mouse: ENSMUSG00000079707, Tcte3, t-complex-associated testis expressed 3, [Score=49.7, Expect=4e-07]; ENSMUSG00000079710, Gm3448, predicted gene 3448, [Score=49.7, Expect=4e-07]; ENSMUSG00000116780, Gm3417, predicted gene 3417, [Score=48.5, Expect=9e-07]} {Smed: dd_Smed_v6_12108_0_1, dd_Smed_v6_12108_0_1, [Score=58.5, Expect=1e-10]} {RNA1509_11021, RNA1509_38233} {RNA1310_29221, RNA1509_38233} {RNA1509_38233, RNA815_16910}
51. MligTC455_18280 44 0.91 Mlig455_020514

Neo: Int S/G2/M

Age: Down-Down-Up

RRS1 1.854 - - - 0.870 - 0.984 Mlig455_020514 {REF} {Length: 1293} {TRANSSPLICED} {Pfam: Ribosome biogenesis regulatory protein (RRS1) [PF04939.14, score=182.2]} {Human: ENSG00000179041, RRS1, ribosome biogenesis regulator homolog, [RH, Score=229, Expect=3e-72]} {Mouse: ENSMUSG00000061024, Rrs1, ribosome biogenesis regulator 1, [RH, Score=229, Expect=5e-72]} {Dmel: FBgn0052409, CG32409, [RH, Score=163, Expect=4e-47]} {Celegans: WBGene00007617, rrbs-1, Ribosome biogenesis regulatory protein homolog, [RH, Score=175, Expect=8e-52]} {Smed: dd_Smed_v6_2458_0_1, dd_Smed_v6_2458_0_1, [RH, Score=105, Expect=1e-26]} {RNA1509_11321} {RNA1310_25851} {RNA815_15109}
52. MligTC455_22998 1192 24.84 Mlig455_001873, Mlig455_001948

Neo: -

Age: logFC(26M/2M)=0.334

Region-enriched R4: 2.809/0.00024
Region-enriched R3: 2.226/0.00227
Region-enriched R5: 1.925/0.00474

GATA4 1.852 - 0.881 - 0.971 - -

Mlig455_001873 {REF} {Length: 2384} {Pfam: GATA zinc finger [PF00320.29, score=98.7]; TFIIB zinc-binding [PF08271.14, score=29.6]; Putative GTPase activating protein for Arf [PF01412.20, score=28.6]} {Human: ENSG00000285109, GATA4, GATA binding protein 4, [Score=172, Expect=6e-47]; ENSG00000136574, GATA4, GATA binding protein 4, [Score=172, Expect=6e-47]; ENSG00000141448, GATA6, GATA binding protein 6, [Score=166, Expect=1e-43]} {Mouse: ENSMUSG00000021944, Gata4, GATA binding protein 4, [Score=173, Expect=1e-47]; ENSMUSG00000005836, Gata6, GATA binding protein 6, [Score=165, Expect=1e-43]; ENSMUSG00000015627, Gata5, GATA binding protein 5, [Score=165, Expect=5e-45]} {Dmel: FBgn0003117, pnr, pannier, [Score=170, Expect=3e-46]} {Celegans: WBGene00001249, elt-1, Transcription factor elt-1, [Score=147, Expect=1e-38]} {Smed: dd_Smed_v6_4075_0_2, dd_Smed_v6_4075_0_2, [RH, Score=143, Expect=2e-36]} {RNA1509_43294} {RNA1310_15255} {RNA815_30190}

Mlig455_001948 {REF} {Length: 2519} {Pfam: GATA zinc finger [PF00320.29, score=98.7]; TFIIB zinc-binding [PF08271.14, score=29.6]; Putative GTPase activating protein for Arf [PF01412.20, score=28.1]} {Human: ENSG00000136574, GATA4, GATA binding protein 4, [Score=172, Expect=6e-47]; ENSG00000285109, GATA4, GATA binding protein 4, [Score=172, Expect=6e-47]; ENSG00000141448, GATA6, GATA binding protein 6, [Score=166, Expect=1e-43]} {Mouse: ENSMUSG00000021944, Gata4, GATA binding protein 4, [Score=172, Expect=2e-47]; ENSMUSG00000005836, Gata6, GATA binding protein 6, [Score=165, Expect=1e-43]; ENSMUSG00000015627, Gata5, GATA binding protein 5, [Score=165, Expect=5e-45]} {Dmel: FBgn0003117, pnr, pannier, [Score=170, Expect=3e-46]} {Celegans: WBGene00001249, elt-1, Transcription factor elt-1, [Score=146, Expect=2e-38]} {Smed: dd_Smed_v6_4075_0_1, dd_Smed_v6_4075_0_1, [RH, Score=143, Expect=1e-36]} {RNA1509_43294} {RNA1310_15255, RNA1509_43294} {RNA1509_43294, RNA815_30190}
53. MligTC455_36665 2410 50.21 Mlig455_028654

Neo: -

Age: logFC(26M/2M)=0.273

Region-enriched R3: 1.404/0.00674

PSAP 1.852 - - - 0.985 0.867 - Mlig455_028654 {REF} {Length: 3951} {Pfam: Saposin-like type B, region 1 [PF05184.17, score=340.1]; Saposin-like type B, region 2 [PF03489.19, score=316.5]; Homeodomain-like domain [PF13384.8, score=47.9]; Helix-turn-helix domain [PF13518.8, score=39.6]; Saposin A-type domain [PF02199.17, score=35.5]; Protein of unknown function (DUF2753) [PF10952.10, score=31.0]; Replication factor RFC1 C terminal domain [PF08519.14, score=24.2]; Winged helix-turn helix [PF13551.8, score=23.7]; HD domain [PF13023.8, score=21.9]; Delta endotoxin [PF18449.3, score=19.6]} {Human: ENSG00000197746, PSAP, prosaposin, [RH, Score=177, Expect=9e-47]} {Mouse: ENSMUSG00000004207, Psap, prosaposin, [RH, Score=154, Expect=6e-39]} {Dmel: FBgn0000416, Sap-r, Saposin-related, [RH, Score=245, Expect=3e-67]} {Smed: dd_Smed_v6_266_0_1, dd_Smed_v6_266_0_1, [Score=99.0, Expect=1e-22]} {RNA1509_1917} {RNA1310_9056} {RNA815_5033.1}
54. MligTC455_49840 1487 30.98 Mlig455_054770, Mlig455_054797

Neo: -

Age: -

Region-enriched R3: 1.670/0.00009
Region-enriched R5: 1.605/0.00002
Region-enriched R4: 1.351/0.01428

ECE1 1.85 - 0.899 - 0.951 - -

Mlig455_054770 {REF} {Length: 3217} {Pfam: Peptidase family M13 [PF05649.15, score=200.5]; Peptidase family M13 [PF01431.23, score=91.3]} {Human: ENSG00000117298, ECE1, endothelin converting enzyme 1, [Score=179, Expect=1e-46]; ENSG00000142606, MMEL1, membrane metalloendopeptidase like 1, [Score=177, Expect=1e-45]; ENSG00000277131, MMEL1, membrane metalloendopeptidase like 1, [Score=177, Expect=1e-45]; ENSG00000171551, ECEL1, endothelin converting enzyme like 1, [Score=174, Expect=7e-45]} {Mouse: ENSMUSG00000058183, Mmel1, membrane metallo-endopeptidase-like 1, [Score=190, Expect=2e-50]} {Dmel: FBgn0029843, Nep1, Neprilysin 1, [Score=182, Expect=2e-47]} {Celegans: WBGene00020230, nep-2, Neprilysin-2, [Score=154, Expect=9e-39]} {Smed: dd_Smed_v6_1910_0_1, dd_Smed_v6_1910_0_1, [Score=160, Expect=7e-41]} {RNA1509_3125} {RNA1310_4911.1, RNA1509_3125} {RNA1509_3125, RNA815_2994}

Mlig455_054797 {REF} {Length: 3127} {Pfam: Peptidase family M13 [PF05649.15, score=200.5]; Peptidase family M13 [PF01431.23, score=92.9]} {Human: ENSG00000117298, ECE1, endothelin converting enzyme 1, [Score=182, Expect=2e-47]; ENSG00000142606, MMEL1, membrane metalloendopeptidase like 1, [Score=179, Expect=1e-46]; ENSG00000277131, MMEL1, membrane metalloendopeptidase like 1, [Score=179, Expect=1e-46]; ENSG00000171551, ECEL1, endothelin converting enzyme like 1, [Score=177, Expect=1e-45]; ENSG00000196549, MME, membrane metalloendopeptidase, [Score=173, Expect=1e-44]} {Mouse: ENSMUSG00000058183, Mmel1, membrane metallo-endopeptidase-like 1, [Score=193, Expect=2e-51]} {Dmel: FBgn0029843, Nep1, Neprilysin 1, [Score=184, Expect=3e-48]} {Celegans: WBGene00020230, nep-2, Neprilysin-2, [Score=157, Expect=1e-39]} {Smed: dd_Smed_v6_1910_0_1, dd_Smed_v6_1910_0_1, [Score=163, Expect=8e-42]} {RNA1509_3125} {RNA1310_4911.1} {RNA815_2994}
55. MligTC455_43721 327 6.82 Mlig455_063423

Neo: -

Age: -

Region-enriched R3: 2.456/0.03595

1.839 - 0.878 - - - 0.961 Mlig455_063423 {REF} {Length: 2914} {TRANSSPLICED} {Pfam: Protein of unknown function (DUF1295) [PF06966.14, score=191.4]; 3-oxo-5-alpha-steroid 4-dehydrogenase [PF02544.18, score=27.0]; Phospholipid methyltransferase [PF04191.15, score=21.1]; Isoprenylcysteine carboxyl methyltransferase (ICMT) family [PF04140.16, score=20.9]} {Dmel: FBgn0035914, CG6282, [RH, Score=167, Expect=2e-49]} {Smed: dd_Smed_v6_14327_0_1, dd_Smed_v6_14327_0_1, [RH, Score=156, Expect=1e-45]} {RNA1509_35384} {RNA1310_33212} {RNA815_13020.1}
56. MligTC455_40902 615 12.81 Mlig455_067443, Mlig455_069598

Neo: -

Age: -

1.837 - - - - 0.872 0.965

Mlig455_067443 {REF} {Length: 4375} {TRANSSPLICED} {RNA1509_8113} {RNA1310_2282.1} {RNA815_1659}

Mlig455_069598 {REF} {Length: 4081} {TRANSSPLICED} {Smed: dd_Smed_v6_15433_0_1, dd_Smed_v6_15433_0_1, [Score=135, Expect=3e-32]} {RNA1509_8113} {RNA1310_2282.1} {RNA815_1659}
57. MligTC455_43692 1533 31.94 Mlig455_010960

Neo: Irradiation

Age: -

Region-specific R4: 4.173

Region-enriched R4: 2.690/0.00000

Regeneration-downregulated R4: -2.347

Regeneration-depleted R4: -2.347

ABCG4 1.83 - - - 0.964 - 0.866 Mlig455_010960 {REF} {Length: 1261} {Pfam: ABC-2 type transporter [PF01061.26, score=140.7]} {Human: ENSG00000172350, ABCG4, ATP binding cassette subfamily G member 4, [Score=125, Expect=6e-31]} {Mouse: ENSMUSG00000032131, Abcg4, ATP binding cassette subfamily G member 4, [Score=123, Expect=2e-30]} {Dmel: FBgn0003996, w, white, [Score=273, Expect=2e-85]} {Celegans: WBGene00015479, wht-1, ABC transporter ATP-binding protein/permease wht-1, [Score=219, Expect=6e-66]} {Smed: dd_Smed_v6_8560_0_1, dd_Smed_v6_8560_0_1, [RH, Score=266, Expect=8e-83]} {RNA1509_6339, RNA1509_6662} {RNA1310_1122.2, RNA1509_6339, RNA1509_6662} {RNA1509_6339, RNA1509_6662, RNA815_3368}
58. MligTC455_42353 5099 106.23 Mlig455_014274, Mlig455_014309, Mlig455_018673

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.786

Region-enriched R3: 2.226/0.00003

AC113554.1, ACE 1.829 - - 0.859 0.970 - -

Mlig455_014274 {REF} {Length: 2949} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=705.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0016122, Acer, Angiotensin-converting enzyme-related, [RH, Score=426, Expect=4e-141]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=191, Expect=3e-51]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=411, Expect=1e-135]} {RNA1509_37062, RNA1509_441} {RNA1310_8949, RNA1509_37062} {RNA1509_37062, RNA815_4061}

Mlig455_014309 {REF} {Length: 2926} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=705.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0016122, Acer, Angiotensin-converting enzyme-related, [RH, Score=426, Expect=4e-141]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=191, Expect=3e-51]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=411, Expect=1e-135]} {RNA1509_441} {RNA1310_8949} {RNA815_4061}

Mlig455_018673 {REF} {Length: 833} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=122.4]} {Human: ENSG00000264813, AC113554.1, novel transcript, [Score=103, Expect=3e-24]; ENSG00000159640, ACE, angiotensin I converting enzyme, [Score=103, Expect=2e-24]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [Score=97.8, Expect=2e-22]; ENSMUSG00000101605, Ace3, angiotensin I converting enzyme (peptidyl-dipeptidase A) 3, [Score=93.2, Expect=6e-21]} {Dmel: FBgn0012037, Ance, Angiotensin converting enzyme, [Score=74.7, Expect=7e-15]} {Smed: dd_Smed_v6_13804_0_1, dd_Smed_v6_13804_0_1, [Score=51.2, Expect=2e-07]} {RNA1509_16360} {RNA1310_8949} {RNA815_4061}
59. MligTC455_35319 995 20.74 Mlig455_038578

Neo: -

Age: -

Region-enriched R4: 1.602/0.03291

ADHFE1 1.827 - 0.867 - 0.960 - - Mlig455_038578 {REF} {Length: 1907} {TRANSSPLICED} {Pfam: Iron-containing alcohol dehydrogenase [PF00465.21, score=346.9]; Iron-containing alcohol dehydrogenase [PF13685.8, score=53.3]; Periplasmic binding protein [PF13458.8, score=20.7]} {Human: ENSG00000147576, ADHFE1, alcohol dehydrogenase, iron containing 1, [RH, Score=519, Expect=0.0]} {Mouse: ENSMUSG00000025911, Adhfe1, alcohol dehydrogenase, iron containing, 1, [RH, Score=516, Expect=0.0]} {Dmel: FBgn0017482, T3dh, Type III alcohol dehydrogenase, [RH, Score=495, Expect=3e-173]} {Celegans: WBGene00012608, hphd-1, Hydroxyacid-oxoacid transhydrogenase, mitochondrial, [RH, Score=448, Expect=8e-155]} {Smed: dd_Smed_v6_4554_0_2, dd_Smed_v6_4554_0_2, [RH, Score=498, Expect=2e-174]} {RNA1509_2515} {RNA1310_11167.2, RNA1509_2515} {RNA1509_2515, RNA815_5063}
60. MligTC455_35660 846 17.62 Mlig455_000402

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=1.182

Region-enriched R3: 1.565/0.00201

AC099489.1 1.817 - 0.861 - 0.956 - - Mlig455_000402 {REF} {Length: 12839} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=92.7]; Domain of unknown function (DUF1943) [PF09172.13, score=67.1]} {Human: ENSG00000188897, AC099489.1, vitellogenin, [Score=129, Expect=8e-29]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=96.3, Expect=2e-19]} {RNA1509_862} {RNA1310_65.1} {RNA815_55}
61. MligTC455_42384 263 5.49 Mlig455_062791

Neo: -

Age: Down-Down-Up

PSPH 1.814 - - - 0.835 - 0.979 Mlig455_062791 {REF} {Length: 1506} {TRANSSPLICED} {Pfam: haloacid dehalogenase-like hydrolase [PF00702.28, score=44.5]; haloacid dehalogenase-like hydrolase [PF12710.9, score=40.6]; Pyrimidine 5'-nucleotidase (UMPH-1) [PF05822.14, score=21.2]} {Human: ENSG00000146733, PSPH, phosphoserine phosphatase, [RH, Score=192, Expect=5e-61]} {Mouse: ENSMUSG00000029446, Psph, phosphoserine phosphatase, [RH, Score=189, Expect=3e-60]} {Dmel: FBgn0023129, aay, astray, [RH, Score=170, Expect=4e-52]} {Celegans: WBGene00013379, Y62E10A.13, [RH, Score=184, Expect=1e-57]} {Smed: dd_Smed_v6_11185_0_1, dd_Smed_v6_11185_0_1, [RH, Score=172, Expect=7e-54]} {RNA1509_6749} {RNA1310_21602, RNA1509_6749} {RNA1509_6749, RNA815_9131}
62. MligTC455_24176 656 13.67 Mlig455_034193

Neo: -

Age: -

PC 1.813 - 0.827 - - - 0.986 Mlig455_034193 {REF} {Length: 2105} {Pfam: Conserved carboxylase domain [PF02436.20, score=162.2]; Biotin-requiring enzyme [PF00364.24, score=59.6]; Biotin-lipoyl like [PF13533.8, score=28.4]; HlyD family secretion protein [PF13437.8, score=24.7]; Na(+)-translocating NADH-quinone reductase subunit A (NQRA) [PF05896.13, score=24.0]} {Human: ENSG00000173599, PC, pyruvate carboxylase, [Score=281, Expect=2e-86]} {Mouse: ENSMUSG00000024892, Pcx, pyruvate carboxylase, [Score=281, Expect=9e-87]} {Dmel: FBgn0027580, PCB, Pyruvate carboxylase, [Score=296, Expect=1e-92]} {Celegans: WBGene00004258, pyc-1, Pyruvate carboxylase 1, [Score=290, Expect=4e-94]} {Smed: dd_Smed_v6_2393_0_1, dd_Smed_v6_2393_0_1, [Score=299, Expect=2e-93]} {RNA1509_30437} {RNA1310_1164.1} {RNA815_728}
63. MligTC455_18225 657 13.69 Mlig455_034956

Neo: -

Age: logFC(26M/2M)=0.287

1.81 - - - 0.982 0.828 - Mlig455_034956 {REF} {Length: 2635} {Pfam: Arrestin (or S-antigen), N-terminal domain [PF00339.31, score=45.3]; Arrestin (or S-antigen), C-terminal domain [PF02752.24, score=40.0]} {Dmel: FBgn0037518, CG2641, [Score=52.4, Expect=4e-07]} {Celegans: WBGene00012464, arrd-7, ARRestin Domain protein, [Score=54.7, Expect=5e-08]} {RNA1509_22116} {RNA1310_8444.1, RNA1509_22116} {RNA1509_22116, RNA815_2910}
64. MligTC455_18975 286 5.97 Mlig455_059132

Neo: Germline

Age: -

Region-enriched R4: 3.652/0.00001

1.808 - - - 0.832 - 0.976 Mlig455_059132 {REF} {Length: 1515} {RNA1509_35598} {RNA1310_23207.1} {RNA815_10106}
65. MligTC455_20189 745 15.51 Mlig455_065227

Neo: -

Age: -

ANO2 1.808 - - - - 0.822 0.986 Mlig455_065227 {REF} {Length: 6049} {Pfam: Calcium-activated chloride channel [PF04547.14, score=496.4]; Dimerisation domain of Ca+-activated chloride-channel, anoctamin [PF16178.7, score=104.2]} {Human: ENSG00000047617, ANO2, anoctamin 2, [RH, Score=539, Expect=7e-176]} {Mouse: ENSMUSG00000038115, Ano2, anoctamin 2, [RH, Score=533, Expect=6e-174]} {Dmel: FBgn0036235, CG6938, [RH, Score=557, Expect=0.0]} {Celegans: WBGene00010138, anoh-1, Anoctamin, [Score=209, Expect=2e-56]} {Smed: dd_Smed_v6_4761_0_1, dd_Smed_v6_4761_0_1, [Score=460, Expect=3e-148]} {RNA1509_13805} {RNA1310_2805.1, RNA1509_13805} {RNA1509_13805, RNA815_1328}
66. MligTC455_18925 1222 25.47 Mlig455_034430

Neo: -

Age: Down-Up-Down

Region-enriched R4: 1.749/0.00485

RGS12 1.804 - - - 0.968 0.836 - Mlig455_034430 {REF} {Length: 1569} {Pfam: Regulator of G protein signaling domain [PF00615.21, score=98.3]} {Human: ENSG00000159788, RGS12, regulator of G protein signaling 12, [Score=112, Expect=3e-26]; ENSG00000169220, RGS14, regulator of G protein signaling 14, [Score=110, Expect=6e-26]} {Mouse: ENSMUSG00000052087, Rgs14, regulator of G-protein signaling 14, [RH, Score=114, Expect=2e-27]} {Dmel: FBgn0020278, loco, locomotion defects, [Score=99.4, Expect=3e-22]} {Celegans: WBGene00004347, rgs-4, Regulator of G protein Signaling, [Score=82.8, Expect=3e-18]} {Smed: dd_Smed_v6_3873_0_1, dd_Smed_v6_3873_0_1, [Score=95.5, Expect=3e-23]} {RNA1509_7258} {RNA1310_21231} {RNA815_8874}
67. MligTC455_43800 4639 96.64 Mlig455_041018, Mlig455_041127, Mlig455_041183

Neo: -

Age: -

RGN 1.804 - - 0.854 0.950 - -

Mlig455_041018 {REF} {Length: 1500} {TRANSSPLICED} {Pfam: SMP-30/Gluconolactonase/LRE-like region [PF08450.14, score=221.4]; Two component regulator propeller [PF07494.13, score=22.9]} {Human: ENSG00000130988, RGN, regucalcin, [RH, Score=187, Expect=4e-57]} {Mouse: ENSMUSG00000023070, Rgn, regucalcin, [RH, Score=190, Expect=3e-58]} {Dmel: FBgn0030362, regucalcin, [Score=142, Expect=6e-40]} {Smed: dd_Smed_v6_3808_0_1, dd_Smed_v6_3808_0_1, [RH, Score=176, Expect=5e-53]} {RNA1509_3252} {RNA1310_20018.1} {RNA815_8819.1}

Mlig455_041127 {REF} {Length: 1500} {TRANSSPLICED} {Pfam: SMP-30/Gluconolactonase/LRE-like region [PF08450.14, score=216.7]; Two component regulator propeller [PF07494.13, score=22.9]} {Human: ENSG00000130988, RGN, regucalcin, [RH, Score=181, Expect=1e-54]} {Mouse: ENSMUSG00000023070, Rgn, regucalcin, [RH, Score=184, Expect=3e-56]} {Dmel: FBgn0038257, smp-30, Senescence marker protein-30, [Score=145, Expect=3e-41]} {Smed: dd_Smed_v6_3808_0_1, dd_Smed_v6_3808_0_1, [RH, Score=178, Expect=8e-54]} {RNA1509_3252} {RNA1310_7497.1} {RNA815_8819.1}

Mlig455_041183 {REF} {Length: 1502} {TRANSSPLICED} {Pfam: SMP-30/Gluconolactonase/LRE-like region [PF08450.14, score=216.7]; Two component regulator propeller [PF07494.13, score=22.9]} {Human: ENSG00000130988, RGN, regucalcin, [RH, Score=182, Expect=5e-55]} {Mouse: ENSMUSG00000023070, Rgn, regucalcin, [RH, Score=186, Expect=9e-57]} {Dmel: FBgn0038257, smp-30, Senescence marker protein-30, [Score=145, Expect=4e-41]} {Smed: dd_Smed_v6_3808_0_1, dd_Smed_v6_3808_0_1, [RH, Score=176, Expect=3e-53]} {RNA1509_3252} {RNA1310_7497.1} {RNA815_8819.1}
68. MligTC455_22027 906 18.88 Mlig455_009586

Neo: -

Age: -

USP49 1.801 - - - 0.824 - 0.977 Mlig455_009586 {REF} {Length: 4256} {TRANSSPLICED} {Pfam: Ubiquitin carboxyl-terminal hydrolase [PF00443.31, score=195.9]; Ubiquitin carboxyl-terminal hydrolase [PF13423.8, score=64.0]} {Human: ENSG00000164663, USP49, ubiquitin specific peptidase 49, [Score=278, Expect=3e-84]; ENSG00000136014, USP44, ubiquitin specific peptidase 44, [Score=273, Expect=6e-82]} {Mouse: ENSMUSG00000090115, Usp49, ubiquitin specific peptidase 49, [Score=284, Expect=2e-86]; ENSMUSG00000020020, Usp44, ubiquitin specific peptidase 44, [Score=283, Expect=6e-86]} {Dmel: FBgn0038862, Usp8, Ubiquitin specific protease 8, [Score=108, Expect=2e-25]} {Celegans: WBGene00010702, usp-33, Ubiquitin carboxyl-terminal hydrolase, [Score=94.0, Expect=8e-20]} {Smed: dd_Smed_v6_6489_0_1, dd_Smed_v6_6489_0_1, [Score=125, Expect=6e-30]} {RNA1509_12069, RNA1509_24259, RNA1509_25953, RNA1509_39809} {RNA1310_7678.1, RNA1509_12069, RNA1509_24259, RNA1509_25953, RNA1509_39809} {RNA1509_12069, RNA1509_24259, RNA1509_25953, RNA1509_39809, RNA815_3720}
69. MligTC455_49253 469 9.77 Mlig455_032060

Neo: -

Age: Up-Down-Up

AAMP 1.796 - - - - 0.822 0.974 Mlig455_032060 {REF} {Length: 2752} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=46.4]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=28.3]} {Human: ENSG00000127837, AAMP, angio associated migratory cell protein, [RH, Score=151, Expect=2e-40]} {Mouse: ENSMUSG00000006299, Aamp, angio-associated migratory protein, [RH, Score=153, Expect=3e-41]} {Dmel: FBgn0036460, CG5114, [RH, Score=94.0, Expect=1e-20]} {Celegans: WBGene00013735, Y111B2A.12, [RH, Score=101, Expect=3e-23]} {Smed: dd_Smed_v6_3496_0_1, dd_Smed_v6_3496_0_1, [Score=47.8, Expect=7e-06]} {RNA1509_15250, RNA1509_29643, RNA1509_30093} {RNA1310_11448.2, RNA1509_15250, RNA1509_29643, RNA1509_30093} {RNA1509_15250, RNA1509_29643, RNA1509_30093, RNA815_11601}
70. MligTC455_17304 101 2.1 Mlig455_031437

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-2.250

Region-enriched R3: 3.738/0.00900

1.794 - - - 0.804 - 0.990 Mlig455_031437 {REF} {Length: 1340} {NoTransDecoderORF} {RNA1509_15660} {RNA1310_6657.1} {RNA815_2791.1}
71. MligTC455_09648 258 5.37 Mlig455_057446

Neo: -

Age: -

1.791 - - - - 0.832 0.959 Mlig455_057446 {REF} {Length: 340} {TRANSSPLICED} {NoTransDecoderORF} {RNA1310_2201} {RNA815_38675}
72. MligTC455_16516 338 7.05 Mlig455_025644

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.431

Region-specific R4: 3.189

Region-enriched R4: 2.435/0.00008

1.787 - - - 0.828 - 0.959 Mlig455_025644 {REF} {Length: 1509} {Pfam: N-formylglutamate amidohydrolase [PF05013.14, score=35.9]} {RNA1509_20433, RNA1509_49439} {RNA1310_23627.1, RNA1509_20433, RNA1509_49439} {RNA1509_20433, RNA1509_49439, RNA815_15550}
73. MligTC455_27356 257 5.36 Mlig455_040046

Neo: -

Age: -

ANK3 1.785 - - - 0.952 0.833 - Mlig455_040046 {REF} {Length: 5322} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=173.8]; Ankyrin repeats (many copies) [PF13637.8, score=162.7]; Ankyrin repeat [PF13606.8, score=133.1]; Ankyrin repeat [PF00023.32, score=128.8]; Ankyrin repeats (many copies) [PF13857.8, score=128.0]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=143, Expect=5e-37]; ENSG00000145362, ANK2, ankyrin 2, [Score=139, Expect=2e-35]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=142, Expect=1e-36]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=138, Expect=2e-35]; ENSMUSG00000031543, Ank1, ankyrin 1, erythroid, [Score=136, Expect=2e-35]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=141, Expect=9e-37]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=151, Expect=3e-40]} {Smed: dd_Smed_v6_7379_0_29, dd_Smed_v6_7379_0_29, [Score=134, Expect=1e-36]} {RNA1509_33337} {RNA1310_2213.1} {RNA815_649.1}
74. MligTC455_14156 746 15.55 Mlig455_033442, Mlig455_040173

Neo: -

Age: -

Region-enriched R3: 1.581/0.04364

1.778 - - 0.820 0.958 - -

Mlig455_033442 {REF} {Length: 1032} {Pfam: Autophagy-related protein 27 [PF09451.12, score=51.4]; Mannose-6-phosphate receptor [PF02157.17, score=30.0]} {RNA1509_43990} {RNA1310_36407, RNA1509_43990} {RNA1509_43990, RNA815_2188.1}

Mlig455_040173 {REF} {Length: 1025} {Pfam: Autophagy-related protein 27 [PF09451.12, score=52.2]; Mannose-6-phosphate receptor [PF02157.17, score=31.3]} {RNA1509_30852, RNA1509_43990} {RNA1310_36407, RNA1509_30852} {RNA1509_30852, RNA815_2188.1}
75. MligTC455_18453 757 15.76 Mlig455_024102

Neo: -

Age: logFC(26M/2M)=-0.279

Region-enriched R3: 1.259/0.01103

FAXC 1.778 - - - 0.784 - 0.994 Mlig455_024102 {REF} {Length: 1414} {Pfam: Glutathione S-transferase N-terminal domain [PF17172.6, score=74.5]; Glutathione S-transferase, C-terminal domain [PF17171.6, score=73.5]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=26.8]; Glutathione S-transferase, C-terminal domain [PF13410.8, score=25.5]; Glutathione S-transferase, C-terminal domain [PF14497.8, score=22.1]} {Human: ENSG00000146267, FAXC, failed axon connections homolog, [Score=119, Expect=3e-30]} {Mouse: ENSMUSG00000028246, Faxc, failed axon connections homolog, [Score=119, Expect=1e-30]} {Dmel: FBgn0014163, fax, failed axon connections, [RH, Score=160, Expect=3e-46]} {Celegans: WBGene00013266, Y57A10A.26, [RH, Score=151, Expect=2e-44]} {Smed: dd_Smed_v6_1736_0_1, dd_Smed_v6_1736_0_1, [RH, Score=270, Expect=2e-90]} {RNA1509_19387, RNA1509_40545} {RNA1310_7046.1, RNA1509_19387, RNA1509_40545} {RNA1509_19387, RNA1509_40545, RNA815_2250.1}
76. MligTC455_50388 1031 21.47 Mlig455_018603, Mlig455_018617

Neo: -

Age: Up-Down-Up

Region-enriched R3: 1.979/0.00000
Region-enriched R4: 1.829/0.00016

SLC8B1 1.776 - - - 0.957 0.819 -

Mlig455_018603 {REF} {Length: 3460} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=150.9]} {Human: ENSG00000089060, SLC8B1, solute carrier family 8 member B1, [RH, Score=215, Expect=5e-60]} {Mouse: ENSMUSG00000032754, Slc8b1, solute carrier family 8 (sodium/lithium/calcium exchanger), member B1, [RH, Score=222, Expect=1e-62]} {Dmel: FBgn0033324, CG14744, [Score=127, Expect=4e-30]} {Celegans: WBGene00003572, ncx-7, Putative sodium/calcium exchanger 7, [RH, Score=169, Expect=8e-44]} {Smed: dd_Smed_v6_9904_0_1, dd_Smed_v6_9904_0_1, [RH, Score=359, Expect=5e-110]} {RNA1509_3073} {RNA1310_3165.1, RNA1509_3073} {RNA1509_3073, RNA815_1390}

Mlig455_018617 {REF} {Length: 1059} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=47.3]} {Human: ENSG00000089060, SLC8B1, solute carrier family 8 member B1, [Score=97.1, Expect=4e-25]} {Mouse: ENSMUSG00000032754, Slc8b1, solute carrier family 8 (sodium/lithium/calcium exchanger), member B1, [Score=95.1, Expect=3e-23]} {Dmel: FBgn0033599, CG13223, [Score=60.5, Expect=3e-11]} {Celegans: WBGene00003572, ncx-7, Putative sodium/calcium exchanger 7, [Score=68.9, Expect=3e-14]} {Smed: dd_Smed_v6_20334_0_5, dd_Smed_v6_20334_0_5, [Score=114, Expect=6e-33]} {RNA1509_3073} {RNA1310_3165.1} {RNA815_1823}
77. MligTC455_41409 1100 22.91 Mlig455_020530

Neo: -

Age: -

1.772 - - - 0.801 - 0.971 Mlig455_020530 {REF} {Length: 4478} {RNA1509_11871} {RNA1310_5093} {RNA815_7109}
78. MligTC455_38362 1015 21.16 Mlig455_045508

Neo: -

Age: -

Region-enriched R4: 1.693/0.01745
Region-enriched R5: 1.163/0.02906

AADAC 1.77 - - 0.799 0.971 - - Mlig455_045508 {REF} {Length: 2224} {Pfam: alpha/beta hydrolase fold [PF07859.15, score=113.1]; Carboxylesterase family [PF00135.30, score=19.9]} {Human: ENSG00000114771, AADAC, arylacetamide deacetylase, [Score=96.3, Expect=2e-21]; ENSG00000197953, AADACL2, arylacetamide deacetylase like 2, [Score=93.6, Expect=2e-20]; ENSG00000261846, AADACL2, arylacetamide deacetylase like 2, [Score=93.6, Expect=2e-20]} {Mouse: ENSMUSG00000090527, Gm5538, predicted gene 5538, [Score=102, Expect=1e-23]; ENSMUSG00000095522, Gm8298, predicted gene 8298, [Score=98.2, Expect=3e-22]} {Dmel: FBgn0034491, Hsl, Hormone-sensitive lipase, [Score=65.5, Expect=4e-11]} {Celegans: WBGene00012810, nceh-1, Neutral Cholesterol Ester Hydrolase homolog, [Score=98.2, Expect=2e-22]} {Smed: dd_Smed_v6_4674_0_1, dd_Smed_v6_4674_0_1, [Score=82.0, Expect=5e-17]} {RNA1509_14307} {RNA1310_15560.2} {RNA815_8354}
79. MligTC455_10989 155 3.22 Mlig455_064790

Neo: Germline

Age: -

Region-enriched R4: 3.654/0.00038

1.764 - - - 0.779 - 0.985 Mlig455_064790 {REF} {Length: 848} {RNA1509_34670} {RNA1310_46959} {RNA815_28830}
80. MligTC455_27415 405 8.43 Mlig455_000570, Mlig455_030368, Mlig455_030416

Neo: -

Age: -

Region-enriched R4: 3.950/0.00080
Region-enriched R5: 2.365/0.01333

NADK 1.764 - - - 0.968 0.796 -

Mlig455_000570 {REF} {Length: 2353} {Pfam: ATP-NAD kinase C-terminal domain [PF20143.1, score=116.1]; ATP-NAD kinase N-terminal domain [PF01513.23, score=36.3]} {Human: ENSG00000008130, NADK, NAD kinase, [RH, Score=264, Expect=2e-82]} {Mouse: ENSMUSG00000029063, Nadk, NAD kinase, [Score=265, Expect=2e-85]} {Dmel: FBgn0053156, CG33156, [Score=263, Expect=1e-84]} {Smed: dd_Smed_v6_8020_0_1, dd_Smed_v6_8020_0_1, [Score=179, Expect=2e-52]} {RNA1509_52179} {RNA1310_11933} {RNA815_29661}

Mlig455_030368 {REF} {Length: 2306} {Pfam: ATP-NAD kinase C-terminal domain [PF20143.1, score=116.3]; ATP-NAD kinase N-terminal domain [PF01513.23, score=36.5]} {Human: ENSG00000008130, NADK, NAD kinase, [RH, Score=281, Expect=7e-91]} {Mouse: ENSMUSG00000029063, Nadk, NAD kinase, [RH, Score=276, Expect=4e-89]} {Dmel: FBgn0053156, CG33156, [Score=269, Expect=2e-87]} {Smed: dd_Smed_v6_8020_0_1, dd_Smed_v6_8020_0_1, [Score=186, Expect=3e-55]} {RNA1509_52179, RNA1509_54734} {RNA1310_11933, RNA1509_52179, RNA1509_54734} {RNA1509_52179, RNA1509_54734, RNA815_21893}

Mlig455_030416 {REF} {Length: 2414} {Pfam: ATP-NAD kinase C-terminal domain [PF20143.1, score=116.3]; ATP-NAD kinase N-terminal domain [PF01513.23, score=36.3]} {Human: ENSG00000008130, NADK, NAD kinase, [RH, Score=282, Expect=3e-91]} {Mouse: ENSMUSG00000029063, Nadk, NAD kinase, [RH, Score=276, Expect=5e-90]} {Dmel: FBgn0053156, CG33156, [Score=271, Expect=3e-88]} {Smed: dd_Smed_v6_8020_0_1, dd_Smed_v6_8020_0_1, [Score=186, Expect=2e-55]} {RNA1509_54734} {RNA1310_11933} {RNA815_21893}
81. MligTC455_45235 418 8.71 Mlig455_044515

Neo: Int S/G2/M

Age: -

GSTT1 1.764 - 0.770 - - - 0.994 Mlig455_044515 {REF} {Length: 1303} {Pfam: Glutathione S-transferase, N-terminal domain [PF02798.22, score=42.4]; Glutathione S-transferase, N-terminal domain [PF13417.8, score=32.2]; Glutathione S-transferase, N-terminal domain [PF13409.8, score=30.2]} {Human: ENSG00000277656, GSTT1, glutathione S-transferase theta 1, [Score=115, Expect=3e-31]} {Mouse: ENSMUSG00000001663, Gstt1, glutathione S-transferase, theta 1, [Score=114, Expect=7e-31]; ENSMUSG00000001665, Gstt3, glutathione S-transferase, theta 3, [Score=111, Expect=3e-30]; ENSMUSG00000092360, Gm20441, predicted gene 20441, [Score=110, Expect=4e-29]} {Dmel: FBgn0050000, GstT1, Glutathione S transferase T1, [Score=95.5, Expect=6e-24]} {Smed: dd_Smed_v6_5451_0_1, dd_Smed_v6_5451_0_1, [Score=94.4, Expect=1e-23]} {RNA1509_7848} {RNA1310_26118} {RNA815_12339}
82. MligTC455_26167 4416 92 Mlig455_001635

Neo: -

Age: -

Region-enriched R3: 1.339/0.03044

TUBB2B 1.76 - 0.806 - 0.954 - - Mlig455_001635 {REF} {Length: 2122} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=239.0]; Tubulin C-terminal domain [PF03953.19, score=140.8]; Misato Segment II tubulin-like domain [PF10644.11, score=23.2]} {Human: ENSG00000137285, TUBB2B, tubulin beta 2B class IIb, [Score=814, Expect=0.0]; ENSG00000137267, TUBB2A, tubulin beta 2A class IIa, [Score=812, Expect=0.0]; ENSG00000196230, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000227739, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000235067, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000232421, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000224156, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000229684, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000183311, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000232575, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000188229, TUBB4B, tubulin beta 4B class IVb, [Score=811, Expect=0.0]; ENSG00000258947, TUBB3, tubulin beta 3 class III, [Score=803, Expect=0.0]; ENSG00000104833, TUBB4A, tubulin beta 4A class IVa, [Score=802, Expect=0.0]; ENSG00000176014, TUBB6, tubulin beta 6 class V, [Score=784, Expect=0.0]; ENSG00000261456, TUBB8, tubulin beta 8 class VIII, [Score=775, Expect=0.0]} {Mouse: ENSMUSG00000001473, Tubb6, tubulin, beta 6 class V, [RH, Score=788, Expect=0.0]} {Dmel: FBgn0284243, betaTub56D, beta-Tubulin at 56D, [Score=773, Expect=0.0]} {Celegans: WBGene00006537, tbb-2, Tubulin beta-2 chain, [Score=781, Expect=0.0]} {Smed: dd_Smed_v6_83_0_3, dd_Smed_v6_83_0_3, [Score=817, Expect=0.0]} {RNA1509_15718, RNA1509_19379, RNA1509_19747, RNA1509_30988, RNA1509_36839, RNA1509_41622, RNA1509_5016} {RNA1310_13968.2, RNA1509_15718, RNA1509_19379, RNA1509_19747, RNA1509_30988, RNA1509_36839, RNA1509_41622, RNA1509_5016} {RNA1509_15718, RNA1509_19379, RNA1509_19747, RNA1509_30988, RNA1509_36839, RNA1509_41622, RNA1509_5016, RNA815_1610.4}
83. MligTC455_48108 469 9.76 Mlig455_005110

Neo: -

Age: Down-Up-Up

SLC47A2 1.756 - 0.796 - 0.960 - - Mlig455_005110 {REF} {Length: 2550} {Pfam: MatE [PF01554.20, score=163.9]; Polysaccharide biosynthesis C-terminal domain [PF14667.8, score=29.8]} {Human: ENSG00000180638, SLC47A2, solute carrier family 47 member 2, [Score=294, Expect=7e-91]; ENSG00000142494, SLC47A1, solute carrier family 47 member 1, [Score=280, Expect=1e-85]} {Mouse: ENSMUSG00000010122, Slc47a1, solute carrier family 47, member 1, [Score=291, Expect=5e-90]; ENSMUSG00000069855, Slc47a2, solute carrier family 47, member 2, [Score=280, Expect=8e-86]} {Smed: dd_Smed_v6_11376_0_1, dd_Smed_v6_11376_0_1, [RH, Score=433, Expect=3e-145]} {RNA1509_37205} {RNA1310_8224.2, RNA1509_37205} {RNA1509_37205, RNA815_3210}
84. MligTC455_52058 1280 26.66 Mlig455_041271

Neo: -

Age: logFC(26M/2M)=0.755

Region-enriched R3: 1.713/0.01206

1.755 - 0.797 - 0.958 - - Mlig455_041271 {REF} {Length: 2151} {Celegans: WBGene00015469, C05D2.8, [RH, Score=207, Expect=2e-62]} {Smed: dd_Smed_v6_8821_0_1, dd_Smed_v6_8821_0_1, [Score=159, Expect=8e-45]} {RNA1509_15031, RNA1509_21776, RNA1509_33962, RNA1509_54125, RNA1509_56588} {RNA1310_13148, RNA1509_15031, RNA1509_21776, RNA1509_33962, RNA1509_54125, RNA1509_56588} {RNA1509_15031, RNA1509_21776, RNA1509_33962, RNA1509_54125, RNA1509_56588, RNA815_7949}
85. MligTC455_18566 341 7.1 Mlig455_041874

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.282

1.754 - 0.795 - - - 0.959 Mlig455_041874 {REF} {Length: 3459} {TRANSSPLICED} {Pfam: Glycosyl transferase family 2 [PF00535.28, score=41.5]; Glycosyltransferase like family 2 [PF13641.8, score=19.5]} {Smed: dd_Smed_v6_6076_0_1, dd_Smed_v6_6076_0_1, [Score=148, Expect=8e-41]} {RNA1509_10264} {RNA1310_5492.1} {RNA815_2741}
86. MligTC455_35818 1219 25.4 Mlig455_017352, Mlig455_017435

Neo: -

Age: Up-Down-Down

ARHGEF12 1.754 - - - 0.776 - 0.978

Mlig455_017352 {REF} {Length: 8693} {TRANSSPLICED} {tRNA: Val(CAC),pseudo, score=20.8} {Pfam: PDZ domain [PF17820.3, score=36.8]; PDZ domain [PF00595.26, score=36.0]; Regulator of G protein signalling-like domain [PF09128.13, score=28.2]; PDZ domain [PF13180.8, score=27.9]; RhoGEF domain [PF00621.22, score=24.1]} {Human: ENSG00000196914, ARHGEF12, Rho guanine nucleotide exchange factor 12, [Score=61.2, Expect=2e-08]} {Mouse: ENSMUSG00000059495, Arhgef12, Rho guanine nucleotide exchange factor (GEF) 12, [Score=60.1, Expect=3e-08]} {Dmel: FBgn0263846, CG43707, [Score=55.5, Expect=7e-07]} {Celegans: WBGene00006468, rhgf-1, RHo Guanine nucleotide exchange Factor, [Score=54.7, Expect=8e-07]} {RNA1509_9517} {RNA1310_569.3} {RNA815_247}

Mlig455_017435 {REF} {Length: 8120} {TRANSSPLICED} {tRNA: Val(CAC),pseudo, score=20.7} {Pfam: Regulator of G protein signalling-like domain [PF09128.13, score=26.7]; RhoGEF domain [PF00621.22, score=22.3]} {RNA1509_9517} {RNA1310_759.2} {RNA815_247}
87. MligTC455_19812 192 3.99 Mlig455_017616

Neo: -

Age: -

1.753 - - - - 0.766 0.987 Mlig455_017616 {REF} {Length: 579} {TRANSSPLICED} {RNA1509_45712} {RNA1310_38057.2} {RNA815_23034.1}
88. MligTC455_49283 671 13.99 Mlig455_001528, Mlig455_046576

Neo: Int S/G2/M

Age: -

Region-enriched R2: 1.859/0.02944

MMACHC 1.752 - - - - 0.770 0.982

Mlig455_001528 {REF} {Length: 1838} {TRANSSPLICED} {Pfam: Methylmalonic aciduria and homocystinuria type C family [PF16690.7, score=156.7]} {Human: ENSG00000132763, MMACHC, methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria, [RH, Score=130, Expect=1e-35]} {Mouse: ENSMUSG00000028690, Mmachc, methylmalonic aciduria cblC type, with homocystinuria, [RH, Score=130, Expect=4e-36]} {Smed: dd_Smed_v6_8584_0_1, dd_Smed_v6_8584_0_1, [RH, Score=114, Expect=3e-30]} {RNA1509_29990, RNA1509_42294} {RNA1310_36622, RNA1509_29990, RNA1509_42294} {RNA1509_29990, RNA1509_42294, RNA815_18456}

Mlig455_046576 {REF} {Length: 1840} {TRANSSPLICED} {Pfam: Methylmalonic aciduria and homocystinuria type C family [PF16690.7, score=157.4]} {Human: ENSG00000132763, MMACHC, methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria, [RH, Score=132, Expect=2e-36]} {Mouse: ENSMUSG00000028690, Mmachc, methylmalonic aciduria cblC type, with homocystinuria, [RH, Score=132, Expect=6e-37]} {Smed: dd_Smed_v6_8584_0_1, dd_Smed_v6_8584_0_1, [RH, Score=114, Expect=6e-30]} {RNA1509_29990, RNA1509_35509, RNA1509_39634} {RNA1310_36622, RNA1509_35509, RNA1509_39634} {RNA1509_35509, RNA1509_39634, RNA815_18456}
89. MligTC455_51137 1192 24.84 Mlig455_011449, Mlig455_061187

Neo: -

Age: -

SDF2 1.752 0.779 - - - - 0.973

Mlig455_011449 {REF} {Length: 2429} {Pfam: MIR domain [PF02815.21, score=53.7]} {Human: ENSG00000132581, SDF2, stromal cell derived factor 2, [Score=214, Expect=1e-69]} {Mouse: ENSMUSG00000002064, Sdf2, stromal cell derived factor 2, [Score=214, Expect=2e-69]} {Dmel: FBgn0037312, CG11999, [Score=197, Expect=4e-63]} {Celegans: WBGene00020038, R12E2.13, [RH, Score=188, Expect=6e-60]} {Smed: dd_Smed_v6_1307_0_1, dd_Smed_v6_1307_0_1, [RH, Score=224, Expect=1e-73]} {RNA1509_21861} {RNA1310_32180} {RNA815_37499}

Mlig455_061187 {REF} {Length: 2509} {Pfam: MIR domain [PF02815.21, score=53.7]} {Human: ENSG00000132581, SDF2, stromal cell derived factor 2, [Score=214, Expect=1e-69]} {Mouse: ENSMUSG00000002064, Sdf2, stromal cell derived factor 2, [Score=214, Expect=2e-69]} {Dmel: FBgn0037312, CG11999, [Score=197, Expect=3e-63]} {Celegans: WBGene00020038, R12E2.13, [RH, Score=188, Expect=6e-60]} {Smed: dd_Smed_v6_1307_0_1, dd_Smed_v6_1307_0_1, [RH, Score=224, Expect=1e-73]} {RNA1509_21861} {RNA1310_32180} {RNA815_37499}
90. MligTC455_20697 51 1.06 Mlig455_032266

Neo: -

Age: -

SLC24A5 1.748 - - - 0.980 0.768 - Mlig455_032266 {REF} {Length: 1815} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=157.9]} {Human: ENSG00000188467, SLC24A5, solute carrier family 24 member 5, [RH, Score=354, Expect=2e-116]} {Mouse: ENSMUSG00000041771, Slc24a4, solute carrier family 24 (sodium/potassium/calcium exchanger), member 4, [Score=365, Expect=2e-119]; ENSMUSG00000035183, Slc24a5, solute carrier family 24, member 5, [Score=353, Expect=2e-116]} {Dmel: FBgn0265767, zyd, zydeco, [Score=330, Expect=1e-107]} {Celegans: WBGene00003569, ncx-4, Na/Ca eXchangers, [Score=276, Expect=2e-85]} {Smed: dd_Smed_v6_7121_0_1, dd_Smed_v6_7121_0_1, [RH, Score=447, Expect=3e-153]} {RNA1310_20949.1} {RNA815_11416}
91. MligTC455_22826 607 12.65 Mlig455_006871

Neo: -

Age: -

ATG4C 1.74 - 0.782 - - - 0.958 Mlig455_006871 {REF} {Length: 5184} {TRANSSPLICED} {Pfam: Peptidase family C54 [PF03416.21, score=188.3]; Ribosomal protein L6 [PF00347.25, score=41.0]} {Human: ENSG00000125703, ATG4C, autophagy related 4C cysteine peptidase, [Score=142, Expect=2e-36]} {Mouse: ENSMUSG00000028550, Atg4c, autophagy related 4C, cysteine peptidase, [Score=137, Expect=1e-34]; ENSMUSG00000002820, Atg4d, autophagy related 4D, cysteine peptidase, [Score=137, Expect=1e-34]} {Dmel: FBgn0038325, Atg4b, Autophagy-related 4b, [Score=134, Expect=9e-33]} {Celegans: WBGene00013595, atg-4.1, Cysteine protease, [Score=127, Expect=1e-31]} {Smed: dd_Smed_v6_10824_0_1, dd_Smed_v6_10824_0_1, [RH, Score=162, Expect=1e-43]} {RNA1509_29780} {RNA1310_15687.1} {RNA815_37674}
92. MligTC455_13476 883 18.4 Mlig455_068605

Neo: -

Age: -

Region-enriched R3: 1.211/0.00517

MESD 1.736 - - - - 0.758 0.978 Mlig455_068605 {REF} {Length: 1476} {TRANSSPLICED} {Pfam: Chaperone for wingless signalling and trafficking of LDL receptor [PF10185.11, score=96.4]} {Human: ENSG00000117899, MESD, mesoderm development LRP chaperone, [RH, Score=82.4, Expect=6e-19]} {Mouse: ENSMUSG00000038503, Mesd, mesoderm development LRP chaperone, [RH, Score=82.8, Expect=2e-19]} {Dmel: FBgn0004132, boca, [RH, Score=71.6, Expect=1e-15]} {Smed: dd_Smed_v6_11790_0_1, dd_Smed_v6_11790_0_1, [RH, Score=78.2, Expect=2e-18]} {RNA1509_19060} {RNA1310_9900} {RNA815_3819.1}
93. MligTC455_38613 969 20.2 Mlig455_048005, Mlig455_063705

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.394

Region-enriched R3: 1.570/0.01256

POSTN 1.736 - - 0.769 0.967 - -

Mlig455_048005 {REF} {Length: 629} {Pfam: Fasciclin domain [PF02469.24, score=22.3]} {Smed: dd_Smed_v6_1088_0_1, dd_Smed_v6_1088_0_1, [Score=52.0, Expect=7e-08]} {RNA1509_6801} {RNA1310_9258} {RNA815_5083}

Mlig455_063705 {REF} {Length: 2741} {Pfam: Fasciclin domain [PF02469.24, score=65.6]} {Human: ENSG00000133110, POSTN, periostin, [Score=67.0, Expect=9e-11]} {Mouse: ENSMUSG00000027750, Postn, periostin, osteoblast specific factor, [Score=63.5, Expect=7e-10]} {Smed: dd_Smed_v6_1088_0_1, dd_Smed_v6_1088_0_1, [Score=141, Expect=9e-35]} {RNA1509_45570, RNA1509_6801} {RNA1310_9258, RNA1509_45570, RNA1509_6801} {RNA1509_45570, RNA1509_6801, RNA815_5083}
94. MligTC455_25051 379 7.89 Mlig455_041234

Neo: -

Age: -

RNF31 1.734 - - - - 0.749 0.985 Mlig455_041234 {REF} {Length: 3579} {Pfam: IBR domain, a half RING-finger domain [PF01485.23, score=35.3]; E3 Ubiquitin Ligase RBR C-terminal domain [PF18091.3, score=30.1]} {Human: ENSG00000285152, RNF31, ring finger protein 31, [Score=188, Expect=8e-50]; ENSG00000092098, RNF31, ring finger protein 31, [Score=188, Expect=8e-50]; ENSG00000284845, AL136295.10, novel transcript, [Score=187, Expect=3e-51]; ENSG00000259529, AL136295.5, novel transcript, [Score=187, Expect=3e-51]} {Mouse: ENSMUSG00000047098, Rnf31, ring finger protein 31, [Score=184, Expect=1e-48]} {Dmel: FBgn0031857, LUBEL, Linear Ubiquitin E3 ligase, [Score=157, Expect=1e-39]} {Smed: dd_Smed_v6_4074_0_1, dd_Smed_v6_4074_0_1, [Score=125, Expect=6e-30]} {RNA1509_34249} {RNA1310_7818.1} {RNA815_8227}
95. MligTC455_31928 995 20.72 Mlig455_033568, Mlig455_034658

Neo: Irradiation

Age: logFC(26M/2M)=-0.676

RTL1, UXS1 1.732 - - - 0.744 - 0.988

Mlig455_033568 {REF} {Length: 3551} {Pfam: GDP-mannose 4,6 dehydratase [PF16363.7, score=197.8]; NAD dependent epimerase/dehydratase family [PF01370.23, score=169.3]; Male sterility protein [PF07993.14, score=39.1]; RmlD substrate binding domain [PF04321.19, score=37.9]; 3-beta hydroxysteroid dehydrogenase/isomerase family [PF01073.21, score=33.1]; Polysaccharide biosynthesis protein [PF02719.17, score=30.9]} {Human: ENSG00000115652, UXS1, UDP-glucuronate decarboxylase 1, [RH, Score=499, Expect=4e-176]} {Mouse: ENSMUSG00000057363, Uxs1, UDP-glucuronate decarboxylase 1, [RH, Score=499, Expect=3e-176]} {Dmel: FBgn0035848, Uxs, UDP-xylose synthase, [RH, Score=482, Expect=2e-169]} {Celegans: WBGene00005019, sqv-1, SQuashed Vulva; UDP-glucuronic acid decarboxylase, [RH, Score=466, Expect=4e-163]} {Smed: dd_Smed_v6_8645_0_1, dd_Smed_v6_8645_0_1, [RH, Score=420, Expect=3e-146]} {RNA1509_14295} {RNA1310_1396.1} {RNA815_549.1}

Mlig455_034658 {REF} {Length: 254} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=102.7]; RNase H-like domain found in reverse transcriptase [PF17919.3, score=95.2]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=81.5]; Integrase zinc binding domain [PF17921.3, score=72.3]; Integrase core domain [PF00665.28, score=28.5]; H2C2 zinc finger [PF09337.12, score=26.4]} {Human: ENSG00000254656, RTL1, retrotransposon Gag like 1, [RH, Score=126, Expect=9e-29]} {Mouse: ENSMUSG00000085925, Rtl1, retrotransposon Gaglike 1, [RH, Score=108, Expect=2e-23]; ENSMUSG00000098639, Rtl1, retrotransposon Gaglike 1, [RH, Score=108, Expect=2e-23]} {Smed: dd_Smed_v6_6563_0_1, dd_Smed_v6_6563_0_1, [Score=329, Expect=4e-97]} {RNA1509_14295} {RNA1310_17172} {RNA815_549.1}
96. MligTC455_12496 154 3.2 Mlig455_017860

Neo: Germline

Age: -

Region-specific R4: 6.044

Region-enriched R4: 4.021/0.00000

1.725 - - - 0.735 - 0.990 Mlig455_017860 {REF} {Length: 622} {NoTransDecoderORF} {RNA1509_26263} {RNA1310_30890} {RNA815_15531}
97. MligTC455_16804 1432 29.83 Mlig455_045198

Neo: -

Age: -

CIAPIN1 1.721 - - - 0.986 - 0.735 Mlig455_045198 {REF} {Length: 1300} {TRANSSPLICED} {Pfam: Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis [PF05093.15, score=81.0]} {Human: ENSG00000005194, CIAPIN1, cytokine induced apoptosis inhibitor 1, [RH, Score=141, Expect=6e-40]} {Mouse: ENSMUSG00000031781, Ciapin1, cytokine induced apoptosis inhibitor 1, [RH, Score=137, Expect=1e-38]} {Dmel: FBgn0001977, CIAPIN1, Cytokine induced apoptosis inhibitor 1, [RH, Score=122, Expect=2e-33]} {Celegans: WBGene00020604, T20B12.7, Anamorsin homolog, [RH, Score=110, Expect=4e-29]} {Smed: dd_Smed_v6_3204_0_1, dd_Smed_v6_3204_0_1, [RH, Score=113, Expect=4e-30]} {RNA1509_10101, RNA1509_12737, RNA1509_9877} {RNA1310_27669, RNA1509_10101, RNA1509_12737, RNA1509_9877} {RNA1509_10101, RNA1509_12737, RNA1509_9877, RNA815_11583.1}
98. MligTC455_15454 681 14.19 Mlig455_063915, Mlig455_063932

Neo: Int S/G2/M

Age: -

Region-enriched R4: 2.242/0.00591
Region-enriched R5: 1.627/0.00625

1.72 - - - 0.752 - 0.968

Mlig455_063915 {REF} {Length: 955} {TRANSSPLICED} {RNA1509_37108} {RNA1310_24097.2} {RNA815_13724}

Mlig455_063932 {REF} {Length: 949} {TRANSSPLICED} {RNA1509_37108} {RNA1310_24097.1} {RNA815_13724}
99. MligTC455_39799 175 3.65 Mlig455_061189

Neo: -

Age: -

LPGAT1 1.72 - - - 0.737 - 0.983 Mlig455_061189 {REF} {Length: 3703} {TRANSSPLICED} {Pfam: Acyltransferase [PF01553.23, score=36.8]; Acyltransferase C-terminus [PF16076.7, score=33.5]} {Human: ENSG00000123684, LPGAT1, lysophosphatidylglycerol acyltransferase 1, [RH, Score=181, Expect=4e-53]} {Mouse: ENSMUSG00000026623, Lpgat1, lysophosphatidylglycerol acyltransferase 1, [RH, Score=187, Expect=6e-56]} {Celegans: WBGene00019465, acl-14, ACyLtransferase-like, [RH, Score=194, Expect=2e-58]} {Smed: dd_Smed_v6_7263_0_1, dd_Smed_v6_7263_0_1, [RH, Score=165, Expect=1e-47]} {RNA1509_42870} {RNA1310_24690, RNA1509_42870} {RNA1509_42870, RNA815_10640}
100. MligTC455_40274 3926 81.79 Mlig455_019584, Mlig455_059113

Neo: -

Age: -

Regeneration-upregulated BL: 1.635

Regeneration-enriched BL: 1.635

ACADVL 1.72 - - 0.768 0.952 - -

Mlig455_019584 {REF} {Length: 2261} {TRANSSPLICED} {Pfam: Acyl-CoA dehydrogenase, C-terminal domain [PF00441.26, score=134.7]; Acyl-CoA dehydrogenase, N-terminal domain [PF02771.18, score=81.6]; Acyl-CoA dehydrogenase, middle domain [PF02770.21, score=78.0]; Acyl-CoA dehydrogenase, C-terminal domain [PF08028.13, score=42.6]} {Human: ENSG00000072778, ACADVL, acyl-CoA dehydrogenase very long chain, [RH, Score=676, Expect=0.0]} {Mouse: ENSMUSG00000018574, Acadvl, acyl-Coenzyme A dehydrogenase, very long chain, [RH, Score=666, Expect=0.0]} {Dmel: FBgn0034432, CG7461, [RH, Score=630, Expect=0.0]} {Celegans: WBGene00017125, acdh-12, Acyl CoA DeHydrogenase, [RH, Score=586, Expect=0.0]} {Smed: dd_Smed_v6_2663_0_1, dd_Smed_v6_2663_0_1, [RH, Score=648, Expect=0.0]} {RNA1509_26329, RNA1509_40058} {RNA1310_8126.1, RNA1509_40058} {RNA1509_40058, RNA815_2564.1}

Mlig455_059113 {REF} {Length: 2212} {Pfam: Acyl-CoA dehydrogenase, C-terminal domain [PF00441.26, score=134.8]; Acyl-CoA dehydrogenase, N-terminal domain [PF02771.18, score=81.7]; Acyl-CoA dehydrogenase, middle domain [PF02770.21, score=78.0]; Acyl-CoA dehydrogenase, C-terminal domain [PF08028.13, score=42.6]} {Human: ENSG00000072778, ACADVL, acyl-CoA dehydrogenase very long chain, [RH, Score=676, Expect=0.0]} {Mouse: ENSMUSG00000018574, Acadvl, acyl-Coenzyme A dehydrogenase, very long chain, [RH, Score=664, Expect=0.0]} {Dmel: FBgn0034432, CG7461, [RH, Score=627, Expect=0.0]} {Celegans: WBGene00017125, acdh-12, Acyl CoA DeHydrogenase, [RH, Score=583, Expect=0.0]} {Smed: dd_Smed_v6_2663_0_1, dd_Smed_v6_2663_0_1, [RH, Score=646, Expect=0.0]} {RNA1509_26329, RNA1509_7197} {RNA1310_8126.1, RNA1509_7197} {RNA1509_7197, RNA815_2564.1}

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