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Results for MligTC455_52423

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_52423 266 5.53 Mlig455_009583

Neo: -

Age: Up-Down-Up

 PLEKHA5 Mlig455_009583 {REF} {Length: 4762} {TRANSSPLICED} {Pfam: PH domain [PF00169.31, score=47.0]} {Human: ENSG00000052126, PLEKHA5, pleckstrin homology domain containing A5, [RH, Score=58.9, Expect=4e-08]} {Mouse: ENSMUSG00000030231, Plekha5, pleckstrin homology domain containing, family A member 5, [RH, Score=59.3, Expect=2e-08]} {Dmel: FBgn0085412, CG34383, [RH, Score=64.7, Expect=4e-10]} {Smed: dd_Smed_v6_6425_0_1, dd_Smed_v6_6425_0_1, [RH, Score=126, Expect=1e-29]} {RNA1509_4182} {RNA1310_2271} {RNA815_8180.1}

Cumulative graph for MligTC455_52423

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.371 2.955 0.86893 1.00000
RegionR2 0.522 2.955 0.48441 0.86779
RegionR3 -0.198 2.955 0.73343 1.00000
RegionR4 0.784 2.955 0.31909 0.63545
RegionR5 -0.811 2.955 0.18375 0.46300
RegionR6 -0.746 2.955 0.24830 0.83421
RegionR7 -0.342 2.955 0.66880 1.00000
RegionR8 0.42 2.955 0.61550 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -4.972 2.955 0.41477 1.00000
RegenerationR2 -0.095 2.955 0.85862 1.00000
RegenerationR3 0.147 2.955 0.82321 0.98883
RegenerationR4 -0.297 2.955 0.67665 0.94447
RegenerationR5 0.31 2.955 0.63368 0.92390
RegenerationR6 0.165 2.955 0.81654 0.98543
RegenerationBL 1.216 2.955 0.09429 0.36065
RegenerationTP -0.788 2.955 0.37080 0.80848


Genes with expression patterns similar to MligTC455_52423

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_52423 266 5.53 Mlig455_009583

Neo: -

Age: Up-Down-Up

 PLEKHA5 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_009583 {REF} {Length: 4762} {TRANSSPLICED} {Pfam: PH domain [PF00169.31, score=47.0]} {Human: ENSG00000052126, PLEKHA5, pleckstrin homology domain containing A5, [RH, Score=58.9, Expect=4e-08]} {Mouse: ENSMUSG00000030231, Plekha5, pleckstrin homology domain containing, family A member 5, [RH, Score=59.3, Expect=2e-08]} {Dmel: FBgn0085412, CG34383, [RH, Score=64.7, Expect=4e-10]} {Smed: dd_Smed_v6_6425_0_1, dd_Smed_v6_6425_0_1, [RH, Score=126, Expect=1e-29]} {RNA1509_4182} {RNA1310_2271} {RNA815_8180.1}
2. MligTC455_34072 454 9.46 Mlig455_029674

Neo: -

Age: logFC(26M/2M)=-0.376

Region-enriched R2: 2.315/0.04888

 3.487 - - 0.973 0.891 0.861 0.762 Mlig455_029674 {REF} {Length: 3896} {Pfam: SH3 domain [PF17902.3, score=34.0]; Plectin repeat [PF00681.22, score=33.8]} {Smed: dd_Smed_v6_16329_0_1, dd_Smed_v6_16329_0_1, [RH, Score=79.3, Expect=4e-15]} {RNA1509_4651} {RNA1310_7377.1, RNA1509_4651} {RNA1509_4651, RNA815_2196}
3. MligTC455_19429 537 11.18 Mlig455_016019

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.664

Region-enriched R2: 1.983/0.00165

 WDR49 2.624 0.785 - 0.960 - - 0.879 Mlig455_016019 {REF} {Length: 4260} {Pfam: WD domain, G-beta repeat [PF00400.34, score=59.6]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=29.3]; EF-hand domain pair [PF13833.8, score=22.2]; EF-hand domain pair [PF13499.8, score=20.7]} {Human: ENSG00000174776, WDR49, WD repeat domain 49, [Score=310, Expect=1e-88]} {Mouse: ENSMUSG00000104301, Wdr49, WD repeat domain 49, [Score=232, Expect=7e-64]; ENSMUSG00000029658, Wdr95, WD40 repeat domain 95, [Score=231, Expect=4e-63]; ENSMUSG00000044083, Efcab8, EF-hand calcium binding domain 8, [Score=226, Expect=9e-60]} {Dmel: FBgn0267449, WDY, WD40 Y, [Score=180, Expect=9e-46]} {Smed: dd_Smed_v6_5437_0_2, dd_Smed_v6_5437_0_2, [Score=306, Expect=3e-87]} {RNA1509_3708} {RNA1310_2384.2, RNA1509_3708} {RNA1509_3708, RNA815_724.1}
4. MligTC455_30801 483 10.05 Mlig455_027631, Mlig455_027642

Neo: -

Age: Up-Down-Down

Region-enriched R4: 2.277/0.03108

 TRPM7 2.554 - - 0.957 - 0.853 0.744

Mlig455_027631 {REF} {Length: 3904} {Pfam: Ion transport protein [PF00520.33, score=35.0]} {Human: ENSG00000092439, TRPM7, transient receptor potential cation channel subfamily M member 7, [Score=79.0, Expect=3e-14]} {Mouse: ENSMUSG00000027365, Trpm7, transient receptor potential cation channel, subfamily M, member 7, [Score=73.9, Expect=5e-13]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=81.6, Expect=2e-15]} {Celegans: WBGene00001651, gon-2, Transient receptor potential channel, [Score=70.5, Expect=3e-12]} {Smed: dd_Smed_v6_26251_0_1, dd_Smed_v6_26251_0_1, [Score=100, Expect=1e-21]} {RNA1509_8759} {RNA1310_4330.3, RNA1509_8759} {RNA1509_8759, RNA815_1383.1}

Mlig455_027642 {REF} {Length: 4185} {Pfam: Ion transport protein [PF00520.33, score=35.0]} {Human: ENSG00000092439, TRPM7, transient receptor potential cation channel subfamily M member 7, [Score=76.3, Expect=1e-13]} {Mouse: ENSMUSG00000027365, Trpm7, transient receptor potential cation channel, subfamily M, member 7, [Score=71.6, Expect=3e-12]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=81.3, Expect=2e-15]} {Celegans: WBGene00001651, gon-2, Transient receptor potential channel, [Score=70.5, Expect=3e-12]} {Smed: dd_Smed_v6_26251_0_1, dd_Smed_v6_26251_0_1, [Score=100, Expect=1e-21]} {RNA1509_8759} {RNA1310_3171.2} {RNA815_1383.1}
5. MligTC455_50741 80 1.66 Mlig455_028260

Neo: -

Age: logFC(26M/2M)=-0.458

Region-enriched R2: 5.649/0.02620

 SFRP5 2.435 - - 0.950 - 0.739 0.746 Mlig455_028260 {REF} {Length: 2580} {Pfam: Fz domain [PF01392.24, score=93.7]} {Human: ENSG00000120057, SFRP5, secreted frizzled related protein 5, [RH, Score=160, Expect=6e-45]} {Mouse: ENSMUSG00000018822, Sfrp5, secreted frizzled-related sequence protein 5, [RH, Score=159, Expect=2e-44]} {Dmel: FBgn0027342, fz4, frizzled 4, [Score=100, Expect=4e-22]} {Celegans: WBGene00022242, sfrp-1, Secreted Frizzled-Related Protein, [RH, Score=162, Expect=3e-46]} {Smed: dd_Smed_v6_13985_0_1, dd_Smed_v6_13985_0_1, [RH, Score=165, Expect=7e-47]} {RNA1509_19129} {RNA1310_15120, RNA1509_19129} {RNA1509_19129, RNA815_29178}
6. MligTC455_45837 631 13.15 Mlig455_055002

Neo: -

Age: -

 1.853 - - 0.953 - - 0.900 Mlig455_055002 {REF} {Length: 821} {RNA1509_3859} {RNA1310_9281} {RNA815_3282}
7. MligTC455_53549 782 16.29 Mlig455_059223

Neo: -

Age: Down-Down-Up

 SIDT1 1.843 - - 0.887 - - 0.956 Mlig455_059223 {REF} {Length: 3659} {TRANSSPLICED} {Pfam: dsRNA-gated channel SID-1 [PF13965.8, score=293.6]} {Human: ENSG00000072858, SIDT1, SID1 transmembrane family member 1, [Score=169, Expect=2e-42]} {Mouse: ENSMUSG00000022696, Sidt1, SID1 transmembrane family, member 1, [Score=158, Expect=4e-39]; ENSMUSG00000034908, Sidt2, SID1 transmembrane family, member 2, [Score=154, Expect=7e-38]} {Celegans: WBGene00006477, chup-1, CHolesterol UPtake associated, [Score=118, Expect=6e-27]} {Smed: dd_Smed_v6_6063_0_2, dd_Smed_v6_6063_0_2, [Score=162, Expect=7e-41]} {RNA1509_26791} {RNA1310_31149.1} {RNA815_1905}
8. MligTC455_27286 330 6.88 Mlig455_017318

Neo: -

Age: -

 1.789 - - 0.959 0.830 - - Mlig455_017318 {REF} {Length: 2873} {RNA1509_26378} {RNA1310_61.2} {RNA815_11919}
9. MligTC455_35416 312 6.5 Mlig455_025858

Neo: -

Age: Down-Down-Up

Region-enriched R2: 2.218/0.01756

 1.773 - - 0.983 - - 0.790 Mlig455_025858 {REF} {Length: 2565} {RNA1509_8462} {RNA1310_23985, RNA1509_8462} {RNA1509_8462, RNA815_9218.1}
10. MligTC455_53960 381 7.93 Mlig455_039523

Neo: -

Age: logFC(26M/2M)=-0.527

Region-enriched R2: 1.863/0.02753

 TTLL7 1.742 0.784 - 0.958 - - - Mlig455_039523 {REF} {Length: 2811} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=44.5]} {Human: ENSG00000137941, TTLL7, tubulin tyrosine ligase like 7, [Score=146, Expect=5e-37]} {Mouse: ENSMUSG00000036745, Ttll7, tubulin tyrosine ligase-like family, member 7, [Score=261, Expect=2e-76]} {Dmel: FBgn0039501, CG5987, [Score=62.8, Expect=5e-10]} {Smed: dd_Smed_v6_13600_0_1, dd_Smed_v6_13600_0_1, [Score=118, Expect=1e-27]} {RNA1509_8901} {RNA1310_4651} {RNA815_1757}
11. MligTC455_28622 626 13.05 Mlig455_028335, Mlig455_066149

Neo: -

Age: Down-Up-Down

 ANO7 1.727 0.961 - - - - 0.766

Mlig455_028335 {REF} {Length: 5358} {TRANSSPLICED} {Pfam: Calcium-activated chloride channel [PF04547.14, score=416.5]; Dimerisation domain of Ca+-activated chloride-channel, anoctamin [PF16178.7, score=98.7]} {Human: ENSG00000146205, ANO7, anoctamin 7, [Score=303, Expect=5e-88]} {Mouse: ENSMUSG00000034107, Ano7, anoctamin 7, [Score=303, Expect=6e-89]} {Dmel: FBgn0036235, CG6938, [Score=279, Expect=2e-78]} {Celegans: WBGene00010138, anoh-1, Anoctamin, [RH, Score=432, Expect=1e-137]} {Smed: dd_Smed_v6_4761_0_1, dd_Smed_v6_4761_0_1, [Score=310, Expect=7e-92]} {RNA1509_16739} {RNA1310_3159} {RNA815_709.1}

Mlig455_066149 {REF} {Length: 4069} {TRANSSPLICED} {Pfam: Calcium-activated chloride channel [PF04547.14, score=416.3]; Dimerisation domain of Ca+-activated chloride-channel, anoctamin [PF16178.7, score=105.2]} {Human: ENSG00000146205, ANO7, anoctamin 7, [Score=301, Expect=6e-87]} {Mouse: ENSMUSG00000034107, Ano7, anoctamin 7, [Score=300, Expect=2e-87]} {Dmel: FBgn0036235, CG6938, [Score=280, Expect=3e-78]} {Celegans: WBGene00010138, anoh-1, Anoctamin, [RH, Score=440, Expect=5e-140]} {Smed: dd_Smed_v6_4761_0_1, dd_Smed_v6_4761_0_1, [Score=311, Expect=4e-92]} {RNA1509_16739} {RNA1310_3045} {RNA815_709.1}
12. MligTC455_50769 157 3.28 Mlig455_011755, Mlig455_019899, Mlig455_047969

Neo: -

Age: -

 ROR1, ROR2 1.685 - - 0.959 - 0.726 -

Mlig455_011755 {REF} {Length: 2365} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=250.7]; Protein kinase domain [PF00069.27, score=106.5]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [Score=328, Expect=5e-102]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [Score=331, Expect=7e-103]} {Dmel: FBgn0010407, Ror, [RH, Score=300, Expect=1e-93]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [RH, Score=228, Expect=4e-65]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [Score=307, Expect=7e-95]} {RNA1509_34377} {RNA1310_12745} {RNA815_11383}

Mlig455_019899 {REF} {Length: 3742} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=248.8]; Protein kinase domain [PF00069.27, score=103.2]; Immunoglobulin I-set domain [PF07679.18, score=46.1]; Immunoglobulin domain [PF13927.8, score=44.2]; Immunoglobulin domain [PF00047.27, score=28.0]; Immunoglobulin domain [PF13895.8, score=27.3]; Fz domain [PF01392.24, score=27.0]; Kringle domain [PF00051.20, score=23.5]} {Human: ENSG00000169071, ROR2, receptor tyrosine kinase like orphan receptor 2, [Score=393, Expect=1e-120]} {Mouse: ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [Score=393, Expect=5e-121]} {Dmel: FBgn0010407, Ror, [RH, Score=300, Expect=3e-89]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [RH, Score=291, Expect=4e-84]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [Score=439, Expect=2e-139]} {RNA1509_34377} {RNA1310_12745, RNA1509_34377} {RNA1509_34377, RNA815_11383}

Mlig455_047969 {REF} {Length: 3775} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=248.3]; Protein kinase domain [PF00069.27, score=104.3]; Immunoglobulin I-set domain [PF07679.18, score=46.2]; Immunoglobulin domain [PF13927.8, score=44.1]; Immunoglobulin domain [PF00047.27, score=28.0]; Immunoglobulin domain [PF13895.8, score=27.3]; Fz domain [PF01392.24, score=27.1]; Kringle domain [PF00051.20, score=22.3]} {Human: ENSG00000169071, ROR2, receptor tyrosine kinase like orphan receptor 2, [Score=387, Expect=7e-119]} {Mouse: ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [Score=386, Expect=1e-118]} {Dmel: FBgn0010407, Ror, [RH, Score=297, Expect=4e-88]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [RH, Score=285, Expect=5e-82]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [Score=441, Expect=3e-140]} {RNA1509_34377} {RNA1310_12745} {RNA815_11383}
13. MligTC455_03841 920 19.16 Mlig455_018790, Mlig455_048140

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.474

Region-enriched R2: 5.915/0.00081

 NKX2-1, NKX2-4 1.679 - - 0.956 - - 0.723

Mlig455_018790 {REF} {Length: 2203} {Pfam: Homeodomain [PF00046.31, score=72.7]} {Human: ENSG00000136352, NKX2-1, NK2 homeobox 1, [RH, Score=145, Expect=2e-39]; ENSG00000125816, NKX2-4, NK2 homeobox 4, [RH, Score=145, Expect=2e-39]} {Mouse: ENSMUSG00000001496, Nkx2-1, NK2 homeobox 1, [RH, Score=145, Expect=2e-39]} {Dmel: FBgn0028993, scro, scarecrow, [RH, Score=166, Expect=8e-47]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [RH, Score=134, Expect=2e-36]} {Smed: dd_Smed_v6_6729_0_1, dd_Smed_v6_6729_0_1, [RH, Score=191, Expect=1e-57]} {RNA1509_12761} {RNA1310_13401} {RNA815_21584}

Mlig455_048140 {REF} {Length: 2218} {Pfam: Homeodomain [PF00046.31, score=72.5]} {Human: ENSG00000125816, NKX2-4, NK2 homeobox 4, [RH, Score=145, Expect=3e-39]; ENSG00000136352, NKX2-1, NK2 homeobox 1, [RH, Score=145, Expect=7e-39]} {Mouse: ENSMUSG00000001496, Nkx2-1, NK2 homeobox 1, [RH, Score=144, Expect=6e-39]} {Dmel: FBgn0028993, scro, scarecrow, [RH, Score=166, Expect=2e-46]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [RH, Score=136, Expect=1e-36]} {Smed: dd_Smed_v6_6729_0_1, dd_Smed_v6_6729_0_1, [RH, Score=193, Expect=1e-57]} {RNA1509_12761} {RNA1310_13401, RNA1509_12761} {RNA1509_12761, RNA815_21584}
14. MligTC455_53961 290 6.04 Mlig455_051313

Neo: -

Age: logFC(26M/2M)=-0.591

Region-enriched R2: 2.488/0.02898

 TTLL7 1.676 0.718 - 0.958 - - - Mlig455_051313 {REF} {Length: 3404} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=247.2]; Sugar-transfer associated ATP-grasp [PF14397.8, score=21.8]; YheC/D like ATP-grasp [PF14398.8, score=18.8]} {Human: ENSG00000137941, TTLL7, tubulin tyrosine ligase like 7, [RH, Score=478, Expect=1e-157]} {Mouse: ENSMUSG00000036745, Ttll7, tubulin tyrosine ligase-like family, member 7, [RH, Score=474, Expect=2e-153]} {Dmel: FBgn0039501, CG5987, [Score=289, Expect=2e-85]} {Celegans: WBGene00019230, ttll-11, Tubulin Tyrosine Ligase Like, [Score=184, Expect=5e-49]} {Smed: dd_Smed_v6_13600_0_1, dd_Smed_v6_13600_0_1, [RH, Score=408, Expect=4e-128]} {RNA1509_8901} {RNA1310_4651, RNA1509_8901} {RNA1509_8901, RNA815_1757}
15. MligTC455_41664 3701 77.1 Mlig455_000787

Neo: -

Age: logFC(26M/2M)=-0.409

 C2orf70 1.665 - 0.706 0.959 - - - Mlig455_000787 {REF} {Length: 695} {TRANSSPLICED} {Pfam: Protein of unknown function (DUF2475) [PF10629.11, score=106.3]} {Human: ENSG00000173557, C2orf70, chromosome 2 open reading frame 70, [RH, Score=129, Expect=8e-38]} {Mouse: ENSMUSG00000029182, 1700001C02Rik, RIKEN cDNA 1700001C02 gene, [RH, Score=110, Expect=1e-30]} {Smed: dd_Smed_v6_3830_0_2, dd_Smed_v6_3830_0_2, [RH, Score=238, Expect=6e-82]} {RNA1509_19064, RNA1509_4169} {RNA1310_38861.1, RNA1509_19064, RNA1509_4169} {RNA1509_19064, RNA1509_4169, RNA815_19362.1}
16. MligTC455_16059 116 2.42 Mlig455_044225

Neo: -

Age: -

 CFAP157 1.661 - - 0.961 - - 0.700 Mlig455_044225 {REF} {Length: 2823} {Pfam: Siphovirus Gp157 [PF05565.13, score=19.9]} {Human: ENSG00000160401, CFAP157, cilia and flagella associated protein 157, [Score=107, Expect=3e-24]} {Mouse: ENSMUSG00000038987, Cfap157, cilia and flagella associated protein 157, [Score=110, Expect=4e-25]} {Dmel: FBgn0036962, CG17122, [Score=67.4, Expect=2e-11]} {Smed: dd_Smed_v6_11523_0_1, dd_Smed_v6_11523_0_1, [Score=62.0, Expect=4e-10]} {RNA1509_42697} {RNA1310_10711} {RNA815_24261}
17. MligTC455_24294 35 0.74 Mlig455_004571

Neo: -

Age: Down-Down-Up

 0.982 - - - - 0.982 - Mlig455_004571 {REF} {Length: 2316} {TRANSSPLICED} {Pfam: Protein of unknown function, DUF547 [PF04784.16, score=123.7]; Glutaredoxin [PF00462.26, score=24.9]} {Celegans: WBGene00012869, Y45F10A.7, [RH, Score=186, Expect=4e-52]} {RNA1310_53091} {RNA815_44593}
18. MligTC455_31614 241 5.03 Mlig455_014958, Mlig455_014959, Mlig455_018348, Mlig455_032699, Mlig455_055151

Neo: -

Age: Down-Up-Down

 0.972 - - 0.972 - - -

Mlig455_014958 {REF} {Length: 198} {NoTransDecoderORF} {RNA1509_30441} {RNA1310_121010} {RNA815_6124}

Mlig455_014959 {REF} {Length: 497} {NoTransDecoderORF} {RNA1509_11969} {RNA1310_21436} {RNA815_64681}

Mlig455_018348 {REF} {Length: 550} {NoTransDecoderORF} {RNA1509_11969} {RNA1310_21436} {RNA815_64681}

Mlig455_032699 {REF} {Length: 431} {NoTransDecoderORF} {RNA1509_11969} {RNA1310_21436} {RNA815_64681}

Mlig455_055151 {REF} {Length: 1771} {NoTransDecoderORF} {RNA1509_11969} {RNA1310_21436} {RNA815_6124}
19. MligTC455_22424 293 6.11 Mlig455_048176, Mlig455_048199

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.971

 0.971 - - 0.971 - - -

Mlig455_048176 {REF} {Length: 2869} {TRANSSPLICED} {Pfam: Orn/Lys/Arg decarboxylase, major domain [PF01276.22, score=336.6]; Orn/Lys/Arg decarboxylase, C-terminal domain [PF03711.17, score=32.0]; Aminotransferase class I and II [PF00155.23, score=28.7]; Beta-eliminating lyase [PF01212.23, score=21.7]; Cys/Met metabolism PLP-dependent enzyme [PF01053.22, score=20.1]} {RNA1509_2305} {RNA1310_6434.1} {RNA815_2364.1}

Mlig455_048199 {REF} {Length: 4544} {TRANSSPLICED} {Pfam: Orn/Lys/Arg decarboxylase, major domain [PF01276.22, score=336.8]; Orn/Lys/Arg decarboxylase, C-terminal domain [PF03711.17, score=32.0]; Aminotransferase class I and II [PF00155.23, score=29.2]; Beta-eliminating lyase [PF01212.23, score=22.1]; Cys/Met metabolism PLP-dependent enzyme [PF01053.22, score=20.3]} {RNA1509_2305} {RNA1310_6434.1} {RNA815_2364.1}
20. MligTC455_21858 21 0.44 Mlig455_045916

Neo: -

Age: -

 SSTR4 0.97 - - 0.970 - - - Mlig455_045916 {REF} {Length: 1682} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=75.9]} {Human: ENSG00000132671, SSTR4, somatostatin receptor 4, [Score=73.2, Expect=1e-13]} {Mouse: ENSMUSG00000037014, Sstr4, somatostatin receptor 4, [Score=82.0, Expect=1e-16]} {Dmel: FBgn0250910, Octbeta3R, Octopamine beta3 receptor, [Score=52.0, Expect=6e-07]} {Celegans: WBGene00020712, ckr-1, CholecystoKinin Receptor homolog, [Score=50.1, Expect=2e-06]} {Smed: dd_Smed_v6_3522_0_1, dd_Smed_v6_3522_0_1, [RH, Score=134, Expect=5e-36]} {RNA1310_148409}
21. MligTC455_53199 76 1.58 Mlig455_035187

Neo: -

Age: Up-Down-Down

 0.969 - - 0.969 - - - Mlig455_035187 {REF} {Length: 4248} {Pfam: MyTH4 domain [PF00784.19, score=60.4]} {Smed: dd_Smed_v6_19214_0_1, dd_Smed_v6_19214_0_1, [RH, Score=172, Expect=1e-46]} {RNA1310_70974} {RNA815_46536}
22. MligTC455_41055 112 2.34 Mlig455_044574

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.659

Region-enriched R2: 6.247/0.00008

 0.966 - - 0.966 - - - Mlig455_044574 {REF} {Length: 1203} {Smed: dd_Smed_v6_9736_0_1, dd_Smed_v6_9736_0_1, [Score=86.7, Expect=1e-20]} {RNA1509_58567} {RNA1310_87689} {RNA815_53353}
23. MligTC455_32328 43 0.89 Mlig455_046579

Neo: -

Age: Down-Up-Down

 TRIM9 0.965 - - 0.965 - - - Mlig455_046579 {REF} {Length: 5213} {Pfam: SPRY domain [PF00622.30, score=46.9]; B-box zinc finger [PF00643.26, score=29.5]; zinc finger of C3HC4-type, RING [PF15227.8, score=24.6]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=24.4]; RING-type zinc-finger [PF13445.8, score=21.9]; Fibronectin type III domain [PF00041.23, score=21.0]; Tc5 transposase DNA-binding domain [PF03221.18, score=20.1]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=18.9]} {Human: ENSG00000100505, TRIM9, tripartite motif containing 9, [Score=476, Expect=2e-151]} {Mouse: ENSMUSG00000021071, Trim9, tripartite motif-containing 9, [Score=476, Expect=2e-151]} {Dmel: FBgn0051721, Trim9, Tripartite motif containing 9, [Score=446, Expect=7e-140]} {Celegans: WBGene00016539, madd-2, [Score=410, Expect=2e-126]} {Smed: dd_Smed_v6_8386_0_1, dd_Smed_v6_8386_0_1, [Score=530, Expect=7e-172]} {RNA1509_37451} {RNA1310_8634.1} {RNA815_9833}
24. MligTC455_53487 49 1.01 Mlig455_006106

Neo: -

Age: Down-Down-Up

 FBXL7 0.963 - - 0.963 - - - Mlig455_006106 {REF} {Length: 3312} {Pfam: F-box-like [PF12937.9, score=46.0]; Leucine Rich repeat [PF13516.8, score=39.7]; F-box domain [PF00646.35, score=28.7]} {Human: ENSG00000183580, FBXL7, F-box and leucine rich repeat protein 7, [Score=151, Expect=3e-39]} {Mouse: ENSMUSG00000043556, Fbxl7, F-box and leucine-rich repeat protein 7, [Score=152, Expect=2e-39]} {Dmel: FBgn0038385, Fbxl7, F-box and leucine-rich repeat protein 7, [Score=154, Expect=2e-39]} {Celegans: WBGene00015350, fbxl-1, Uncharacterized F-box/LRR-repeat protein C02F5.7, [Score=99.8, Expect=4e-22]} {Smed: dd_Smed_v6_10647_0_1, dd_Smed_v6_10647_0_1, [Score=102, Expect=8e-23]} {RNA1310_5789.1} {RNA815_11910}
25. MligTC455_53488 50 1.05 Mlig455_055274

Neo: -

Age: -

 FBXL7 0.963 - - 0.963 - - - Mlig455_055274 {REF} {Length: 3372} {Pfam: Leucine Rich repeat [PF13516.8, score=59.3]; F-box-like [PF12937.9, score=46.1]; Leucine Rich repeats (2 copies) [PF12799.9, score=35.0]; F-box domain [PF00646.35, score=27.2]} {Human: ENSG00000183580, FBXL7, F-box and leucine rich repeat protein 7, [RH, Score=174, Expect=5e-49]} {Mouse: ENSMUSG00000043556, Fbxl7, F-box and leucine-rich repeat protein 7, [RH, Score=176, Expect=2e-49]} {Dmel: FBgn0038385, Fbxl7, F-box and leucine-rich repeat protein 7, [Score=171, Expect=2e-46]} {Celegans: WBGene00015350, fbxl-1, Uncharacterized F-box/LRR-repeat protein C02F5.7, [Score=112, Expect=4e-27]} {Smed: dd_Smed_v6_10647_0_1, dd_Smed_v6_10647_0_1, [RH, Score=111, Expect=3e-26]} {RNA1310_5789.1} {RNA815_11910}
26. MligTC455_37713 37 0.77 Mlig455_071045

Neo: -

Age: -

 0.961 - - 0.961 - - - Mlig455_071045 {REF} {Length: 895} {TRANSSPLICED} {Pfam: Transcriptional Coactivator p15 (PC4) [PF02229.18, score=26.0]} {RNA1509_13774} {RNA1310_6053.2} {RNA815_16908}
27. MligTC455_11361 145 3.02 Mlig455_034224

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.480

 LRP8 0.96 - - 0.960 - - - Mlig455_034224 {REF} {Length: 4100} {Pfam: Low-density lipoprotein receptor domain class A [PF00057.20, score=47.2]} {Human: ENSG00000157193, LRP8, LDL receptor related protein 8, [Score=75.9, Expect=1e-13]; ENSG00000130164, LDLR, low density lipoprotein receptor, [Score=74.3, Expect=3e-13]; ENSG00000168702, LRP1B, LDL receptor related protein 1B, [Score=73.9, Expect=9e-13]; ENSG00000137642, SORL1, sortilin related receptor 1, [Score=72.8, Expect=1e-12]} {Mouse: ENSMUSG00000028613, Lrp8, low density lipoprotein receptor-related protein 8, apolipoprotein e receptor, [Score=75.5, Expect=1e-13]; ENSMUSG00000049252, Lrp1b, low density lipoprotein-related protein 1B (deleted in tumors), [Score=75.1, Expect=2e-13]; ENSMUSG00000049313, Sorl1, sortilin-related receptor, LDLR class A repeats-containing, [Score=72.0, Expect=2e-12]} {Dmel: FBgn0004649, yl, yolkless, [Score=68.9, Expect=1e-11]} {Celegans: WBGene00015083, egg-1, EGG sterile (Unfertilizable), [Score=74.3, Expect=1e-13]} {Smed: dd_Smed_v6_9829_0_1, dd_Smed_v6_9829_0_1, [Score=71.6, Expect=8e-13]} {RNA1509_15509} {RNA1310_7577, RNA1509_15509} {RNA1509_15509, RNA815_6380}
28. MligTC455_28344 63 1.32 Mlig455_043590

Neo: -

Age: -

 0.96 - - 0.960 - - - Mlig455_043590 {REF} {Length: 676} {NoTransDecoderORF} {RNA1509_51983} {RNA1310_29347} {RNA815_21467}
29. MligTC455_51984 22 0.47 Mlig455_043080

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=3.138

 0.96 - - 0.960 - - - Mlig455_043080 {REF} {Length: 2180} {TRANSSPLICED} {Pfam: Ubiquitin-conjugating enzyme [PF00179.28, score=40.1]} {Smed: dd_Smed_v6_3423_0_1, dd_Smed_v6_3423_0_1, [Score=80.9, Expect=6e-18]} {RNA1509_23666} {RNA1310_19234.1} {RNA815_18307}
30. MligTC455_37257 309 6.44 Mlig455_048693

Neo: -

Age: logFC(26M/2M)=-0.514

 GAS8 0.959 - - 0.959 - - - Mlig455_048693 {REF} {Length: 2216} {Pfam: Growth-arrest specific micro-tubule binding [PF13851.8, score=273.6]} {Human: ENSG00000141013, GAS8, growth arrest specific 8, [RH, Score=634, Expect=0.0]} {Mouse: ENSMUSG00000040220, Gas8, growth arrest specific 8, [RH, Score=628, Expect=0.0]} {Dmel: FBgn0029667, Gas8, Growth arrest specific protein 8, [RH, Score=370, Expect=8e-124]} {Smed: dd_Smed_v6_2848_0_1, dd_Smed_v6_2848_0_1, [RH, Score=667, Expect=0.0]} {RNA1509_4695} {RNA1310_10753.1} {RNA815_4143}
31. MligTC455_50846 98 2.04 Mlig455_063437, Mlig455_063465

Neo: -

Age: Down-Up-Down

 MPEG1 0.958 - - 0.958 - - -

Mlig455_063437 {REF} {Length: 2494} {Pfam: MAC/Perforin domain [PF01823.21, score=65.4]} {Human: ENSG00000197629, MPEG1, macrophage expressed 1, [Score=344, Expect=7e-108]} {Mouse: ENSMUSG00000046805, Mpeg1, macrophage expressed gene 1, [Score=335, Expect=1e-104]; ENSMUSG00000040065, Pfpl, pore forming protein-like, [Score=323, Expect=4e-100]} {Smed: dd_Smed_v6_983_0_1, dd_Smed_v6_983_0_1, [Score=322, Expect=3e-100]} {RNA1310_13506.2} {RNA815_6129.1}

Mlig455_063465 {REF} {Length: 2046} {Human: ENSG00000197629, MPEG1, macrophage expressed 1, [Score=174, Expect=2e-46]} {Mouse: ENSMUSG00000046805, Mpeg1, macrophage expressed gene 1, [Score=164, Expect=6e-43]; ENSMUSG00000040065, Pfpl, pore forming protein-like, [Score=160, Expect=7e-42]} {Smed: dd_Smed_v6_12605_0_1, dd_Smed_v6_12605_0_1, [Score=145, Expect=2e-38]} {RNA1310_13506.2} {RNA815_6129.1}
32. MligTC455_23983 21 0.44 Mlig455_025539, Mlig455_025557

Neo: -

Age: -

 0.957 - - 0.957 - - -

Mlig455_025539 {REF} {Length: 532} {NoTransDecoderORF}

Mlig455_025557 {REF} {Length: 3448} {RNA1509_50956} {RNA1310_70245} {RNA815_29876}
33. MligTC455_28250 29 0.6 Mlig455_023431, Mlig455_066326

Neo: -

Age: -

 0.957 - - 0.957 - - -

Mlig455_023431 {REF} {Length: 181} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_57805} {RNA1310_49040} {RNA815_8074.2}

Mlig455_066326 {REF} {Length: 616} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_57805} {RNA1310_9829} {RNA815_8074.2}
34. MligTC455_50664 138 2.87 Mlig455_035152

Neo: -

Age: -

Region-enriched R2: 3.712/0.01441

 LRRC74A 0.957 - - 0.957 - - - Mlig455_035152 {REF} {Length: 2523} {TRANSSPLICED} {Pfam: Leucine Rich repeat [PF13516.8, score=68.7]; Leucine Rich Repeat [PF00560.35, score=35.6]; Leucine Rich repeats (2 copies) [PF12799.9, score=31.8]; Leucine rich repeat [PF13855.8, score=22.7]} {Human: ENSG00000100565, LRRC74A, leucine rich repeat containing 74A, [Score=146, Expect=1e-37]; ENSG00000187905, LRRC74B, leucine rich repeat containing 74B, [Score=144, Expect=1e-37]} {Mouse: ENSMUSG00000059114, Lrrc74a, leucine rich repeat containing 74A, [Score=147, Expect=5e-38]; ENSMUSG00000022759, Lrrc74b, leucine rich repeat containing 74B, [Score=144, Expect=1e-37]} {Dmel: FBgn0033212, LRR, Leucine-rich repeat, [Score=51.6, Expect=2e-06]} {Celegans: WBGene00009201, F28C1.3, Protein phosphatase 1 regulatory subunit 37 homolog, [Score=55.5, Expect=8e-08]} {Smed: dd_Smed_v6_14506_0_1, dd_Smed_v6_14506_0_1, [Score=147, Expect=6e-38]} {RNA1509_21228} {RNA1310_12842} {RNA815_17243}
35. MligTC455_14602 75 1.57 Mlig455_048086

Neo: -

Age: -

 ANO4 0.956 - - 0.956 - - - Mlig455_048086 {REF} {Length: 3765} {Pfam: Calcium-activated chloride channel [PF04547.14, score=386.9]; Dimerisation domain of Ca+-activated chloride-channel, anoctamin [PF16178.7, score=62.2]} {Human: ENSG00000151572, ANO4, anoctamin 4, [Score=392, Expect=6e-123]; ENSG00000171714, ANO5, anoctamin 5, [Score=384, Expect=2e-120]; ENSG00000047617, ANO2, anoctamin 2, [Score=382, Expect=8e-119]; ENSG00000131620, ANO1, anoctamin 1, [Score=380, Expect=6e-120]; ENSG00000177119, ANO6, anoctamin 6, [Score=376, Expect=8e-118]; ENSG00000134343, ANO3, anoctamin 3, [Score=376, Expect=6e-117]} {Mouse: ENSMUSG00000035189, Ano4, anoctamin 4, [Score=387, Expect=3e-121]; ENSMUSG00000034107, Ano7, anoctamin 7, [Score=381, Expect=4e-120]; ENSMUSG00000055489, Ano5, anoctamin 5, [Score=379, Expect=3e-120]; ENSMUSG00000064210, Ano6, anoctamin 6, [Score=378, Expect=4e-118]; ENSMUSG00000031075, Ano1, anoctamin 1, calcium activated chloride channel, [Score=378, Expect=5e-118]; ENSMUSG00000038115, Ano2, anoctamin 2, [Score=377, Expect=3e-117]; ENSMUSG00000074968, Ano3, anoctamin 3, [Score=372, Expect=2e-115]} {Dmel: FBgn0036235, CG6938, [Score=385, Expect=1e-118]} {Celegans: WBGene00010138, anoh-1, Anoctamin, [Score=162, Expect=2e-41]} {Smed: dd_Smed_v6_19189_0_1, dd_Smed_v6_19189_0_1, [Score=352, Expect=9e-111]} {RNA1509_13805} {RNA1310_9037} {RNA815_32354}
36. MligTC455_17429 31 0.65 Mlig455_007460

Neo: -

Age: -

 IFT27 0.956 - - 0.956 - - - Mlig455_007460 {REF} {Length: 970} {Pfam: Ras family [PF00071.24, score=120.4]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=54.3]} {Human: ENSG00000100360, IFT27, intraflagellar transport 27, [Score=123, Expect=3e-34]} {Mouse: ENSMUSG00000016637, Ift27, intraflagellar transport 27, [Score=130, Expect=3e-37]} {Dmel: FBgn0015795, Rab7, [Score=84.7, Expect=1e-19]} {Celegans: WBGene00004271, rab-7, RAB family, [Score=85.1, Expect=7e-20]} {Smed: dd_Smed_v6_11026_0_1, dd_Smed_v6_11026_0_1, [Score=122, Expect=3e-34]} {RNA1310_14163} {RNA815_25254}
37. MligTC455_43454 36 0.74 Mlig455_043999

Neo: -

Age: -

 0.955 - - 0.955 - - - Mlig455_043999 {REF} {Length: 2456} {Dmel: FBgn0259222, CG42322, [RH, Score=101, Expect=3e-22]} {Smed: dd_Smed_v6_18554_0_1, dd_Smed_v6_18554_0_1, [Score=82.4, Expect=1e-17]} {RNA1310_20749} {RNA815_38231}
38. MligTC455_40497 258 5.37 Mlig455_005650

Neo: -

Age: -

Region-enriched R2: 3.635/0.02759

 SLC1A2 0.954 - - 0.954 - - - Mlig455_005650 {REF} {Length: 2712} {Pfam: Sodium:dicarboxylate symporter family [PF00375.20, score=259.1]} {Human: ENSG00000110436, SLC1A2, solute carrier family 1 member 2, [Score=214, Expect=1e-61]; ENSG00000162383, SLC1A7, solute carrier family 1 member 7, [Score=212, Expect=4e-61]; ENSG00000079215, SLC1A3, solute carrier family 1 member 3, [Score=211, Expect=6e-61]; ENSG00000106688, SLC1A1, solute carrier family 1 member 1, [Score=207, Expect=1e-59]; ENSG00000105143, SLC1A6, solute carrier family 1 member 6, [Score=204, Expect=7e-58]} {Mouse: ENSMUSG00000005089, Slc1a2, solute carrier family 1 (glial high affinity glutamate transporter), member 2, [Score=229, Expect=3e-67]; ENSMUSG00000020142, Slc1a4, solute carrier family 1 (glutamate/neutral amino acid transporter), member 4, [Score=225, Expect=3e-66]; ENSMUSG00000001918, Slc1a5, solute carrier family 1 (neutral amino acid transporter), member 5, [Score=221, Expect=1e-64]} {Dmel: FBgn0026439, Eaat1, Excitatory amino acid transporter 1, [Score=216, Expect=2e-63]} {Celegans: WBGene00001620, glt-1, Excitatory amino acid transporter, [Score=235, Expect=1e-70]} {Smed: dd_Smed_v6_1106_0_1, dd_Smed_v6_1106_0_1, [Score=231, Expect=2e-69]} {RNA1509_23441, RNA1509_40224, RNA1509_45320} {RNA1310_8169.3, RNA1509_23441, RNA1509_40224, RNA1509_45320} {RNA1509_23441, RNA1509_40224, RNA1509_45320, RNA815_2675.1}
39. MligTC455_41054 33 0.7 Mlig455_029071

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.560

 SLC24A2 0.952 - - 0.952 - - - Mlig455_029071 {REF} {Length: 3162} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=167.5]} {Human: ENSG00000155886, SLC24A2, solute carrier family 24 member 2, [Score=280, Expect=2e-84]} {Mouse: ENSMUSG00000037996, Slc24a2, solute carrier family 24 (sodium/potassium/calcium exchanger), member 2, [Score=278, Expect=8e-84]} {Dmel: FBgn0028704, Nckx30C, [Score=254, Expect=2e-73]} {Celegans: WBGene00003569, ncx-4, Na/Ca eXchangers, [Score=236, Expect=6e-69]} {Smed: dd_Smed_v6_9736_0_1, dd_Smed_v6_9736_0_1, [RH, Score=532, Expect=0.0]} {RNA1509_23781} {RNA1310_15750.1, RNA1509_23781} {RNA1509_23781, RNA815_4071}
40. MligTC455_42570 2049 42.69 Mlig455_053258, Mlig455_065035

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.321

 0.952 - - - 0.952 - -

Mlig455_053258 {REF} {Length: 1743} {Pfam: EF-hand domain pair [PF13499.8, score=31.4]; EF hand [PF00036.34, score=24.3]; EF hand [PF13202.8, score=19.7]; EF-hand domain [PF13405.8, score=19.2]} {Smed: dd_Smed_v6_9661_0_1, dd_Smed_v6_9661_0_1, [Score=63.9, Expect=2e-12]} {RNA1509_25077} {RNA1310_19802} {RNA815_7187.1}

Mlig455_065035 {REF} {Length: 1711} {Pfam: EF-hand domain pair [PF13499.8, score=31.4]; EF hand [PF00036.34, score=24.1]; EF hand [PF13202.8, score=19.3]; EF-hand domain [PF13405.8, score=18.9]} {Smed: dd_Smed_v6_9661_0_1, dd_Smed_v6_9661_0_1, [Score=62.8, Expect=7e-12]} {RNA1509_25077, RNA1509_34131, RNA1509_57236} {RNA1310_19802, RNA1509_34131, RNA1509_57236} {RNA1509_34131, RNA1509_57236, RNA815_7187.1}
41. MligTC455_32428 352 7.33 Mlig455_013946

Neo: -

Age: -

 NWD2 0.951 - - 0.951 - - - Mlig455_013946 {REF} {Length: 7112} {TRANSSPLICED} {Pfam: NACHT domain [PF05729.14, score=45.6]; AAA ATPase domain [PF13191.8, score=41.4]; Domain of unknown function (DUF4062) [PF13271.8, score=40.6]; AAA domain [PF13401.8, score=24.5]; ATPase domain predominantly from Archaea [PF01637.20, score=20.2]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=431, Expect=4e-131]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [Score=426, Expect=2e-129]} {Dmel: FBgn0038397, CG10185, [Score=520, Expect=4e-164]} {Celegans: WBGene00020254, T05C3.2, [Score=530, Expect=2e-167]} {Smed: dd_Smed_v6_11085_0_1, dd_Smed_v6_11085_0_1, [Score=323, Expect=7e-94]} {RNA1509_3054} {RNA1310_322} {RNA815_139.1}
42. MligTC455_17628 869 18.11 Mlig455_036459

Neo: -

Age: Down-Up-Up

 0.95 - - - - - 0.950 Mlig455_036459 {REF} {Length: 1261} {RNA1509_16798} {RNA1310_48718, RNA1509_16798} {RNA1509_16798, RNA815_24350}
43. MligTC455_34792 238 4.96 Mlig455_045574

Neo: -

Age: logFC(26M/2M)=-0.239

 0.95 - - 0.950 - - - Mlig455_045574 {REF} {Length: 4478} {Smed: dd_Smed_v6_27312_0_1, dd_Smed_v6_27312_0_1, [RH, Score=160, Expect=9e-40]} {RNA1509_6675} {RNA1310_2307, RNA1509_6675} {RNA1509_6675, RNA815_650}

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